JP2014018172A - Pet food inhibiting production of lipid peroxide - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide pet food having a function of inhibiting accumulation of lipid peroxide in a living body such as a dog and a cat, and capable of maintaining health of a pet while reducing industrial waste by utilizing a byproduct of meat which cannot be used for food for a human, as a raw material.SOLUTION: Glutathione is added to pet food for a dog and a cat. An addition amount of glutathione per 1 kg dry weight of pet food is preferably 50 to 1000 mg, and more preferably 100 to 400 mg. A byproduct of meat may be used as a raw material of the pet food.

Description

  The present invention relates to a pet food for maintaining the health of pets such as dogs and cats.

  In the human body, lipid peroxide accumulation in the body is considered to be a cause of diseases and aging such as arteriosclerosis, diabetes, dementia, and cancer, and it is almost the same in dogs and cats.

  On the other hand, internal products such as bones, blood, and intestines that are produced when cattle, pigs, and other livestock are slaughtered and parts that are consumed by humans are removed. It is used. This by-product contains a very large amount of iron, for example, the raw meat meal contains 500 mg / kg of iron. While the standard value of human iron intake is 2.25-10mg / day / person, the standard value of iron defined by AAFCO, the standard for pet food, is 80-3000mg / kg (dog food dry weight). Widely set. Therefore, most common pet foods are considered to be iron-rich due to raw materials.

  In the body, oxygen breaks down food and produces peroxide when it generates energy, but if excessively accumulated iron is present in the body, it reacts with oxygen and increases peroxide. End up. In other words, it is considered that pet food with a high iron content increases the lipid peroxide in the body of dogs and cats who consume it.

In recent years, there has been a growing need to make pets such as dogs and cats live as long as possible, and pet foods that meet such requirements have been developed. One of them is pet food with low iron content that does not use bi-product as a raw material. However, such a pet food naturally has a very high manufacturing cost and a high product unit price.
There is a demand for the development of pet food that does not promote lipid peroxide accumulation at a low cost while effectively using a by-product that is a waste part in human consumption.

  Patent Document 1 describes that glutathione has a lipid peroxide scavenging action. However, this document only describes in vitro data in which TBA value was measured after adding glutathione to an oxidized linoleic acid suspension and stirring. It was not known whether lipid peroxide in the living body could be eliminated.

JP-A-5-276895

An object of the present invention is to provide a pet food having a function of suppressing lipid peroxide accumulation in living bodies of dogs and cats. Another object of the present invention is to provide a pet food that can maintain the health of pets while reducing industrial waste by using raw meat by-products that cannot be used for human consumption as raw materials.

  The inventors of the present invention can significantly reduce the lipid peroxide level in the blood of a dog that has consumed glutathione by adding glutathione to the pet food, that is, a pet food with a high iron content using a bi-product as a raw material. In addition, it was found that lipid peroxide accumulation can be suppressed by adding glutathione.

That is, the present invention
(1) Dog and cat food supplemented with glutathione,
(2) Provided is a lipid peroxide reducing agent for dogs or cats that contains glutathione as an active ingredient and is orally ingested by dogs or cats.

  The pet food of the present invention can reduce the amount of lipid peroxide in the body of dogs and cats. In addition, even if it is contained in pet food that contains a lot of iron, the effect is demonstrated, so that it is possible to use livestock by-products with confidence as a raw material for pet food, contributing to the reduction of industrial waste. .

As used herein, glutathione refers to reduced glutathione, oxidized glutathione, or a mixture thereof.
The form of glutathione to be added may be anything as long as it contains glutathione. Examples include yeast or yeast extract containing glutathione, vegetables such as broccoli and pumpkin, fruits such as orange and avocado, meat such as chicken, pork and cow liver, beef shank, and refined glutathione.
Examples of yeasts containing glutathione include “Hythion Cobo MG” (manufactured by Kojin), and yeast extracts containing glutathione include “Hythione extract YH” (manufactured by Kojin).

  The pet food referred to in the present invention is a dog or cat food or beverage. The shape may be any of a dry solid, a solid containing water, a bowl, a liquid, and the like. In order to maintain glutathione stably for a long period of time, a dry solid state is desirable during storage.

  In the present invention, the pet food may be a so-called by-product that is not edible for human consumption among livestock meat as a raw material. Usually, the pet food using the bi-product has an iron content of 80 mg / kg or more and an excessive amount of iron. However, the addition of glutathione eliminates the harmful effects caused by the addition.

  When glutathione or a substance containing the same is fed to a pet as a lipid peroxide reducing agent, the amount of glutathione per individual is preferably 5 mg to 500 mg / day, and more preferably 10 mg to 100 mg / day. Therefore, when glutathione or a product containing it is added to pet food, the amount depends on the type of dog or cat, but the glutathione addition amount per kg of pet food dry weight is desirably 50 mg to 1000 mg, and 100 mg to 400 mg. Is more desirable. When the amount is less than 50 mg, the effect of reducing lipid peroxide is difficult to be obtained. When the amount is more than 1000 mg, the taste may change and the palatability may be lowered.

  Since glutathione is unstable to heat, it is desirable not to overheat after compounding. Therefore, glutathione or a substance containing the same can be added to pet food at the time of feeding.

Hereinafter, the present invention will be specifically described with reference to examples.
<Example 1>
Twelve 2-14 year old dogs (7 males and 5 females) were used as test dogs. All are healthy, castrated and uncontraceptive, and are not pregnant.
Using “Imus adult lamb and rice” (manufactured by P & G Pet) having an iron content of 34 mg / g as a dog food, this was used as a standard food. Moreover, what added Haithion Cobo MG (glutathione content 3% or more, manufactured by Kojin) to 330 mg / kg (test dog body weight) / day was prepared as a test meal.
The above 12 test dogs that had been fed with a standard diet for 3 months or longer were fed with the test diet for 4 weeks. Blood was collected once before feeding the test meal and after giving the test meal for 4 weeks. The blood was stored at −30 ° C. after serum separation until analysis. For the measurement of the lipid peroxide content of this serum, an MDA (malondialdehyde) measurement kit (manufactured by Japan Aging Control Laboratory) was used. This kit is generally used as a major marker of lipid peroxidation.
The results are shown in Table 1.

As shown in Table 1, the blood lipid peroxide concentration of dogs fed with a standard diet hardly changed after 4 weeks, but dogs fed with a test diet supplemented with glutathione for 4 weeks The lipid concentration was reduced to 46% before the feeding test, and the effect of adding glutathione was noticeable.

Glutathione is given orally to dogs and cats to reduce lipid peroxidation in the body, so it can be added to dog foods, cat foods, beverages, etc. .

Claims (2)

Pet food for dogs and cats with glutathione added. An agent for reducing lipid peroxide in dogs or cats, which contains glutathione as an active ingredient and is orally ingested by dogs or cats.