JP2025065188A - Fungicide composition - Google Patents

Abstract

To provide a disinfectant composition that is applied to a cleaning aid with bacterial buildup to achieve both high disinfecting effects and low substrate damage, and a method for disinfecting a cleaning aid using the same.SOLUTION: A disinfectant composition includes the following component (a) of 0.001 mass% or more and 10 mass% or less, the following component (b) of 0.1 mass% or more, the following component (c) of 0.1 mass% or more and 10 mass% or less, and water. Component (a): a disinfectant, component (b): at least one surfactant selected from ampholytic surfactants and nonionic surfactants, and component (c): a penetrant.SELECTED DRAWING: None

Description

The present invention relates to a disinfectant composition and a method for sterilizing cleaning aids using the same. In particular, the present invention relates to a disinfectant composition suitable for sterilizing cleaning aids for toilets and/or bathrooms, a disinfectant product in a spray container in which the composition is filled in a container equipped with a sprayer, and a method for sterilizing cleaning aids.

When cleaning toilets, bathrooms, and kitchens, cleaning tools such as sponges and brushes are used to scrub. These cleaning tools accumulate a large amount of dirt that serves as food for bacteria and mold, and because they are constantly moist, they are an ideal environment for the proliferation of these microorganisms. Cleaning tools that have bacteria growing on them are not only prone to producing a foul odor, but also cause the bacteria to become more likely to become contaminated when contaminated cleaning tools are used to clean a surface that needs to be kept clean, so daily care of cleaning tools is required.

Patent Document 1 discloses technology related to a toilet cleaner that contains a β-glucuronidase inhibitor, a surfactant such as an alkyl glycoside, and an antibacterial agent such as didecyldimethylammonium chloride, and is therefore effective in both antibacterial properties and in eliminating malodors.

JP 2010-162321 A

Unlike hard surfaces, worn cleaning aids accumulate dirt over time as they are used for cleaning, allowing bacteria to grow and making it difficult to obtain the effects of bactericides or antibacterial agents, so there is a demand for further improvement in bactericidal power. However, in order to increase the bactericidal power, it is possible to consider a method of increasing the content of a bactericide, such as bleach or a bactericidal solvent, in the bactericidal composition. However, when this bactericidal composition is applied to a cleaning aid, there is a tendency for the cleaning aid to be more susceptible to damage to the substrate, such as dissolution or loss of strength, in a cleaning aid made of a sponge or the like made of a material containing urethane bonds.

The present invention provides a disinfectant composition that combines high disinfecting power with minimal damage to the substrate for cleaning aids on which bacteria have accumulated, and a method for disinfecting cleaning aids using the same.

The present invention relates to a disinfectant composition comprising: 0.001% by mass or more and 10% by mass or less of the following component (a); 0.1% by mass or more of the following component (b); 0.1% by mass or more and 10% by mass or less of the following component (c); and water:
Component (a): a disinfectant; Component (b): one or more surfactants selected from amphoteric surfactants and nonionic surfactants; Component (c): a penetrating agent

The present invention also relates to a disinfectant product in a spray container, which is a container equipped with a sprayer and contains the disinfectant composition of the present invention.

The present invention also relates to a method for sterilizing a cleaning aid by contacting the cleaning aid with the disinfectant composition of the present invention.

The present invention provides a disinfectant composition that has both high disinfecting power and low damage to the substrate of cleaning aids on which bacteria have accumulated, and a method for disinfecting cleaning aids using the same.

The reason why the disinfectant composition of the present invention and the method for disinfecting a cleaning aid using the same achieve both high disinfecting power and low damage to the substrate of a cleaning aid on which bacteria have accumulated is not entirely clear, but is presumed to be as follows.
In a worn-out cleaning aid, bacteria accumulate deep inside, and in order to obtain a high bactericidal power, it is important to make the bactericidal composition penetrate deep inside the cleaning aid and sterilize the bacteria accumulated inside.Usually, in order to increase the bactericidal power, a method is considered in which the bactericidal composition penetrates into the cleaning aid by using a large amount of the bactericidal composition or by lengthening the action time, but in this case, the damage to the substrate, such as dissolution or strength reduction of the cleaning aid, tends to increase.Therefore, in order to achieve both high bactericidal power and low damage to the substrate, it is required to make a small amount of the bactericidal composition act efficiently in a short time on the cleaning aid with accumulated bacteria.
Therefore, it is presumed that the germicide composition of the present invention contains the (a) component, the (b) component, and the (c) component, and the (a) component, which is a germicide, penetrates into the inside of the cleaning auxiliary tool efficiently by the (b) component and the (c) component, thereby enabling sterilization in a small amount and in a short time. Furthermore, since the germicide composition of the present invention has a specific foam property, it is preferable to use it in a foam form, and further, it is more preferable to use the germicide composition of the present invention in a foam form by containing the (a) component, the (b) component, and the (c) component in a specific ratio. In the preferred embodiment of the germicide composition of the present invention, by using it in a foam form, the (a) component, which is a germicide, can be uniformly applied to a wide range of the cleaning auxiliary tool due to an appropriate foam specific volume, and further, since the applied foam becomes unstable and breaks in a short time, it is presumed that the (a) component becomes liquid and efficiently penetrates into the inside of the cleaning auxiliary tool, enabling sterilization in a small amount and in a short time. In order to have such foam properties, it is preferable that the germicide composition of the present invention contains the (a) component, the (b) component, and the (c) component in a specific ratio.

[Fungicide composition]
<Component (a)>
The fungicide composition of the present invention contains a fungicide as component (a).
The (a) component may be one or more selected from (a1) a quaternary ammonium salt (hereinafter referred to as the (a1) component), (a2) an oxidizing agent-based bactericide (hereinafter referred to as the (a2) component), (a3) sulfamic acid or a salt thereof (hereinafter referred to as the (a3) component), (a4) a metal-based bactericide (hereinafter referred to as the (a4) component), (a5) a polyamino acid (hereinafter referred to as the (a5) component), and (a6) a polyhexamethylene biguanide or a salt thereof (hereinafter referred to as the (a6) component). From the viewpoint of bactericidal effect and substrate damage, one selected from the (a1), (a2), and (a4) components is preferred, and the (a1) component is more preferred.

From the viewpoint of the bactericidal effect, the (a1) component is preferably one or more selected from (a11) a compound represented by the following general formula (a11) (hereinafter referred to as the (a11) component) and (a12) a compound represented by the following general formula (a12) (hereinafter referred to as the (a12) component).

[In the formula, R ^11a is an aliphatic hydrocarbon group having from 8 to 18 carbon atoms, R ^12a is a group selected from an aliphatic hydrocarbon group having from 8 to 18 carbon atoms, an alkyl group having from 1 to 3 carbon atoms, and a hydroxyalkyl group having from 1 to 3 carbon atoms, R ^13a and R ^14a are each independently a group selected from an alkyl group having from 1 to 3 carbon atoms, and a hydroxyalkyl group having from 1 to 3 carbon atoms, and X ⁻ is an anion.]

[In the formula, R ^15a is a hydrocarbon group having 8 to 18 carbon atoms which may be interrupted by an oxygen atom or a nitrogen atom, R ^16a and R ^17a are each independently a group selected from an alkyl group having 1 to 3 carbon atoms and a hydroxyalkyl group having 1 to 3 carbon atoms, and X ⁻ is an anion.]

In general formula (a11), from the viewpoint of the bactericidal effect, the number of carbon atoms in R ^11a is 8 or more, preferably 10 or more, more preferably 12 or more, and preferably 18 or less, more preferably 16 or less, and even more preferably 14 or less. R ^11a is preferably an alkyl group or an alkenyl group, and more preferably an alkyl group.
In general formula (a11), R ^12a represents a group selected from an aliphatic hydrocarbon group having from 8 to 18 carbon atoms, an alkyl group having from 1 to 3 carbon atoms, and a hydroxyalkyl group having from 1 to 3 carbon atoms, and is preferably an alkyl group having from 1 to 3 carbon atoms.
When R ^12a is an aliphatic hydrocarbon group having from 8 to 18 carbon atoms, from the viewpoint of the bactericidal effect, R ^12a is preferably an alkyl or alkenyl group having 8 or more, preferably 10 or more, more preferably 12 or more, and preferably 18 or less, more preferably 16 or less, and even more preferably 14 or less, and is preferably an alkyl group.

In general formula (a11), R ^13a and R ^14a are each independently a group selected from an alkyl group having 1 to 3 carbon atoms and a hydroxyalkyl group having 1 to 3 carbon atoms. ^{R 13a} and R ^14a are each preferably independently an alkyl group having 1 to 3 carbon atoms. Examples of the alkyl group having 1 to 3 carbon atoms include a methyl group, an ethyl group, and a propyl group. Examples of the hydroxyalkyl group having 1 to 3 carbon atoms include a hydroxymethyl group, a hydroxyethyl group, and a hydroxypropyl group.

In general formula (a11), X ⁻ is an anion. Examples of the anion include halogen ions such as chloride ions, bromide ions, and iodide ions. Examples of the anion also include alkyl sulfate ions having 1 to 3 carbon atoms such as methyl sulfate ions, ethyl sulfate ions, and propyl sulfate ions.

Preferred compounds of the general formula (a11) include one or more selected from N-alkyl-N,N,N-trimethylammonium salts in which the alkyl group has 12 to 18 carbon atoms, N,N-dialkyl-N,N-dimethyl-ammonium salts in which the alkyl group has 8 to 16 carbon atoms, and N-alkyl-N,N-dimethyl-N-ethylammonium salts in which the alkyl group has 12 to 16 carbon atoms.

In formula (a12), R ^15a is preferably an aliphatic hydrocarbon group having from 8 to 18 carbon atoms or a group represented by the following formula:

and more preferably an aliphatic hydrocarbon group having from 8 to 18 carbon atoms. From the viewpoint of the bactericidal effect, the number of carbon atoms in ^{R 15a} is preferably 8 or more, more preferably 10 or more, and preferably 18 or less, more preferably 16 or less, and even more preferably 14 or less. R ^15a is preferably an alkyl group or an alkenyl group, and more preferably an alkyl group.

In general formula (a12), R ^16a and R ^17a are each independently a group selected from an alkyl group having 1 to 3 carbon atoms and a hydroxyalkyl group having 1 to 3 carbon atoms. ^{R 16a} and R ^17a are each preferably independently an alkyl group having 1 to 3 carbon atoms. Examples of the alkyl group having 1 to 3 carbon atoms include a methyl group, an ethyl group, and a propyl group. Examples of the hydroxyalkyl group having 1 to 3 carbon atoms include a hydroxymethyl group, a hydroxyethyl group, and a hydroxypropyl group.

In the general formula (a12), ^X- is an anion. Examples of the anion include halogen ions such as chloride ions, bromide ions, and iodide ions. Examples of the anion also include alkyl sulfate ions having 1 to 3 carbon atoms such as methyl sulfate ions, ethyl sulfate ions, and propyl sulfate ions.

Specific examples of the compound of general formula (a12) include N-octyl-N,N-dimethyl-N-benzyl ammonium salt, N-decyl-N,N-dimethyl-N-benzyl ammonium salt, N-dodecyl-N,N-dimethyl-N-benzyl ammonium salt, N-tridecyl-N,N-dimethyl-N-benzyl ammonium salt, N-tetradecyl-N,N-dimethyl-N-benzyl ammonium salt, N-pentadecyl-N,N-dimethyl-N-benzyl ammonium salt, N-hexadecyl-N,N-dimethyl-N-benzyl ammonium salt, N-dodecyl-N,N-diethyl-N-benzyl ammonium salt, N-tridecyl-N,N-diethyl-N-benzyl ammonium salt, and N-tetradecyl-N,N-diethyl-N-benzyl ammonium salt. , N-pentadecyl-N,N-diethyl-N-benzyl ammonium salt, N-hexadecyl-N,N-diethyl-N-benzyl ammonium salt, N-dodecyl-N-methyl-N-ethyl-N-benzyl ammonium salt, N-tridecyl-N-methyl-N-ethyl-N-benzyl ammonium salt, N-tetradecyl-N-methyl-N-ethyl-N-benzyl ammonium salt, N-pentadecyl-N-methyl-N-ethyl-N-benzyl ammonium salt, N-hexadecyl-N-methyl-N-ethyl-N-benzyl ammonium salt, and N,N-dimethyl-N-[2-[2-[4-(1,1,3,3-tetramethylbutyl)phenyl]oxy]ethoxy]ethyl]benzenemethanaminium salt.

The oxidizing agent-based disinfectant of the component (a2) may be one or more selected from hypochlorous acid or its salts, hydrogen peroxide, percarbonate, perborate, perphosphate, persilicate, and peracetic acid or its salts. The hypochlorite, percarbonate, perborate, perphosphate, persilicate, and peracetic acid salts are preferably alkali metal salts such as sodium salts.
From the viewpoint of bactericidal effect, the component (a2) is preferably one or more selected from hypochlorous acid or a salt thereof, hydrogen peroxide, percarbonate, and peracetic acid or a salt thereof, and more preferably hypochlorous acid or a salt thereof.

The component (a3) is sulfamic acid or a salt thereof. Examples of sulfamate salts include alkali metal salts such as sodium salts, and alkaline earth metal salts such as calcium salts.

The metal-based bactericide of the (a4) component includes a carrier in which a silver and/or zinc complex is ion-exchanged or supported, and an organic silver compound or a carrier in which it is ion-exchanged or supported. Examples of carriers in which a silver and/or zinc complex is ion-exchanged or supported include silica alumina magnesium, calcium phosphate, silica gel, glass, zeolite, zirconium phosphate, and calcium silicate. Specifically, silver zeolite, silver zirconium phosphate, etc. can be mentioned.
The organic silver compound is silver complexed with a polymer or an amino acid. The organic silver compound may be ion-exchanged or supported on a carrier. Specifically, those described in paragraphs 0012 to 0024 of JP-A-2020-076103 can be used.

The polyamino acid of component (a5) may be one or more selected from protamine, polylysine, lysozyme, and nisin, with polylysine being preferred from the standpoint of bactericidal effect.

Polylysine is a polyamino acid in which the essential amino acid L-lysine is polymerized in a linear chain, and examples of polylysine include α-polylysine produced by chemical synthesis and ε-polylysine produced by fermentation. From the viewpoint of bactericidal properties, polylysine is preferably ε-polylysine. From the viewpoint of bactericidal properties, the molecular weight of polylysine is preferably 3,000 or more, more preferably 4,000 or more, and preferably 10,000 or less, more preferably 8,000 or less, more preferably 6,000 or less, and more preferably 5,000 or less. This molecular weight is a weight average molecular weight measured by the GPC-LALLS method. Moreover, from the viewpoint of safety, polylysine is preferably polylysine of a quality level that can be used as a food additive.

The protamine is not particularly limited, but may be protamine purified from nucleoprotamine present in the sperm nucleus of one or more fish species selected from a group consisting of about 50 or more fish species, including salmon, herring, rainbow trout, and tuna, by treating the milt with acid. From the viewpoints of bactericidal properties, safety, economy, and availability, protamine is preferably protamine obtained from the milt of salmon, herring, rainbow trout, tuna, or mullet, and more preferably protamine obtained from the milt of salmon. From the viewpoint of safety, protamine is preferably protamine of a quality level that can be used as a food or food additive.
Examples of protamine include free protamine, protamine, or a salt thereof. From the viewpoints of bactericidal properties and compatibility, protamine is preferably one or more selected from protamine salts, more preferably protamine sulfate and protamine hydrochloride, and from the viewpoint of availability, more preferably protamine hydrochloride.

Examples of lysozyme include, but are not limited to, egg white lysozyme, which is a food additive separated and purified from chicken egg white, and lysozyme chloride.

Nisin is a peptide consisting of 34 amino acids produced by Lactococcus lactis subsp. lactis isolated from fermented milk. Nisin is not particularly limited, but a mixture of antibacterial polypeptides obtained from the culture medium of Lactococcus lactis subsp. lactis and sodium chloride, etc., can be used.

Specific examples of the polyhexamethylene biguanide or salt thereof that can be used as component (a6) include those described in paragraphs 0025 to 0027 of JP 2020-076103 A.

<Component (b)>
The disinfectant composition of the present invention contains, as component (b), one or more surfactants selected from (b1) an amphoteric surfactant (hereinafter referred to as component (b1)) and (b2) a nonionic surfactant (hereinafter referred to as component (b2)) for the purpose of improving disinfection properties due to basic surfactant actions such as wetting and cleaning of stains.

The amphoteric surfactant of component (b1) may be one or more selected from (b11) amine oxide surfactants (hereinafter referred to as component (b11)) and (b12) betaine surfactants (hereinafter referred to as component (b12)).

As the amine oxide surfactant of component (b11), a compound of the following general formula (b11) is preferred.

[In the formula, R ^11b represents an alkyl group or alkenyl group having 7 to 22 carbon atoms, more preferably an alkyl group; R ^12b and R ^13b may be the same or different and represent an alkyl group having 1 to 3 carbon atoms; D represents an -NHC(=O)- group or a -C(=O)NH- group; E represents an alkylene group having 1 to 5 carbon atoms; and q and p represent q=0 and p=0 or q=1 and p=1.]

In the above general formula (b11), when q = 1 and p = 1, R ^11b is, from the viewpoint of improving bactericidal activity, a hydrocarbon group, preferably an alkyl group, having 9 or more, preferably 11 or more, and 18 or less, preferably 16 or less, and more preferably 14 or less carbon atoms.
When q = 0 and p = 0, R ^11b is, from the viewpoint of improving the bactericidal activity, a hydrocarbon group, preferably an alkyl group, having 10 or more carbon atoms, preferably 12 or more, and 18 or less, preferably 16 or less, more preferably 14 or less. In the present invention, it is preferable that q = 0 and p = 0. ^{R 12b} and R ^13b are preferably a methyl group having 1 carbon atom.

Examples of the component (b12) include betaine type surfactants, preferably sulfobetaine type surfactants, or carbobetaine type surfactants having one or more, preferably one, alkyl or alkenyl group having 7 to 22 carbon atoms.
As the betaine surfactant, a compound represented by the following general formula (b12) is preferable.

[In the formula, R ^14b is an alkyl or alkenyl group having 7 to 18 carbon atoms, and R ^15b is an alkylene group having 1 to 6 carbon atoms. A is a group selected from -COO-, -CONH-, -OCO-, -NHCO-, and -O-, and r is the number 0 or 1. ^{R 16b} and R ^17b are alkyl or hydroxyalkyl groups having 1 to 3 carbon atoms, and R ^18b is an alkylene group having 1 to 5 carbon atoms which may be substituted with a hydroxy group. B is -SO ₃ ^- , -OSO ₃ ^- , or ^-COO- .]

In general formula (b12), R ^14b represents an alkyl or alkenyl group, preferably an alkyl group, having 7 or more, preferably 10 or more, and 18 or less, preferably 14 or less, more preferably 12 or less, carbon atoms, from the viewpoint of improving bactericidal activity.
A is preferably --COO-- or --CONH--, and more preferably --CONH--.
R ^15b preferably has 2 or 3 carbon atoms, and more preferably has 3 carbon atoms.
r is preferably 1.
R ^16b and R ^17b are preferably methyl groups.
R ^18b preferably has 1 carbon atom.
B is preferably ^--COO-- .

Specific examples of betaine surfactants include one or more selected from alkyl carboxybetaines, alkyl amido carboxybetaines, alkyl sulfobetaines, alkyl hydroxysulfobetaines, alkyl amido hydroxysulfobetaines, and alkyl amino fatty acid salts. From the viewpoints of improved disinfection properties, cleaning properties, and foaming properties, preferred are one or more selected from alkyl amido propyl-N,N-dimethyl carboxybetaines and alkyl-N,N-dimethyl acetate betaines. These alkyl groups have 7 or more carbon atoms, preferably 10 or more, and 18 or less, preferably 14 or less, and more preferably 12 or less.

From the viewpoint of improving bactericidal properties, the nonionic surfactant of component (b2) is preferably one or more selected from (b21) polyoxyalkylene alkyl or alkenyl ether (hereinafter referred to as component (b21)), (b22) alkyl (poly)glycoside (hereinafter referred to as component (b22)), and (b23) alkyl glyceryl ether (hereinafter referred to as component (b23)).

The alkyl group or alkenyl group in component (b21) is preferably an alkyl group, and the number of carbon atoms in the alkyl group or alkenyl group is preferably 10 or more, more preferably 12 or more, and preferably 20 or less, more preferably 18 or less, and even more preferably 16 or less, from the viewpoint of improving bactericidal activity.
The oxyalkylene group in the component (b21) is selected from an oxyethylene group and an oxypropylene group, and is preferably an oxyethylene group.
From the viewpoint of improving bactericidal activity, the average number of moles of oxyalkylene groups added in the (b21) component is preferably 2 or more, more preferably 4 or more, even more preferably 6 or more, and preferably 20 or less, more preferably 18 or less, even more preferably 13 or less, and still more preferably 10 or less.

As the alkyl (poly)glycoside of the component (b22), a compound of the following general formula (b22) is preferred.
R ^21b - (OR ^22b ) _p G _q (b22)
[In the formula, R ^21b is an alkyl group having 8 to 18 carbon atoms, R ^22b is an alkylene group having 2 to 4 carbon atoms, G is a residue derived from a reducing sugar, p is a number of 0 to 6 indicating the average number of moles of oxyalkylene groups added, and p R ^22b may be the same or different. q indicates the average degree of condensation of G and is a number of 1 to 10.]

In general formula (b22), R ^21b represents an alkyl group having 8 or more, preferably 9 or more, and 18 or less, preferably 16 or less, more preferably 14 or less, carbon atoms, from the viewpoint of improving bactericidal activity.
R ^22b is an alkylene group having 2 to 4 carbon atoms, preferably an ethylene group or a propylene group, and more preferably an ethylene group.
p represents the average number of moles of oxyalkylene groups added and is a number of 0 or more and 6 or less, preferably 3 or less, more preferably 1 or less, and further preferably 0.
q represents the average degree of condensation of G, and is a number from 1 to 10, preferably 5 or less, and more preferably 2 or less, from the viewpoint of improving bactericidal activity.
Examples of G include residues derived from monosaccharides such as glucose, galactose, xylose, mannose, lyxose, arabinose, fructose, or mixtures thereof, and examples of G include residues derived from disaccharides or more such as maltose, xylobiose, isomaltose, cellobiose, gentiobiose, lactose, sucrose, nigerose, turanose, raffinose, gentianose, menzitose, or mixtures thereof. Among these, preferred raw materials are glucose and fructose for monosaccharides and maltose and sucrose for disaccharides or more from the viewpoint of blend stability.

Specific examples of the (b23) component include alkyl glyceryl ethers having one alkyl group with 8 to 18 carbon atoms, preferably 8 to 14 carbon atoms, and more preferably 8 to 12 carbon atoms. Examples of the alkyl group of the (b23) component include branched alkyl groups having 8 to 12 carbon atoms, preferably 8 to 10 carbon atoms, and from the viewpoint of improving bactericidal properties, 2-ethylhexyl, isononyl, or isodecyl groups are preferred, and 2-ethylhexyl groups are more preferred. From the viewpoint of improving bactericidal properties, the (b23) component is preferably an alkyl glyceryl ether having one alkyl group with 8 to 12 carbon atoms, and 2-ethylhexyl glyceryl ether is more preferred.

<Component (c)>
The fungicide composition of the present invention contains a penetrant as component (c).
In the present invention, the penetrant refers to an agent that improves the penetration of the germicide (a) into bacteria present inside the cleaning auxiliary tool.

From the viewpoint of improving the bactericidal properties based on the improved permeability of component (a) to bacteria present inside the cleaning aid, component (c) is preferably one or more selected from alcohols, glycol ethers, alkanolamines, and silicates.

The alcohols include one or more selected from ethanol, 1-propanol, 2-propanol, ethylene glycol, diethylene glycol, triethylene glycol, low molecular weight polyethylene glycol, propylene glycol, dipropylene glycol, low molecular weight polypropylene glycol, glycerin, diglycerin, polyglycerin, and benzyl alcohol.

As the glycol ether, a compound represented by the following general formula (c1) is preferable.
R ^1c O-(R ^2c O) _n -H (c1)
(In the formula, R ^1c is a hydrocarbon group having 1 to 8 carbon atoms, preferably an alkyl group, an alkenyl group, or an aryl group; R ^2c is an alkylene group having 2 or 3 carbon atoms; and n is an integer of 1 or more and 4 or less, preferably 3 or less, and more preferably 2 or less.)

Specific examples of glycol ethers include one or more selected from methyl propylene glycol, phenoxyethanol, butyl diglycol, phenyl diglycol, 2-ethylhexyl glycol, hexyl glycol, hexyl diglycol, butyl propylene diglycol, butyl propylene glycol, propyl propylene diglycol, butyl glycol, propyl propylene glycol, 2-tert-butoxyethanol, isobutyl diglycol, methyl glycol, methyl dipropylene glycol, benzyl glycol, and benzyl diglycol.

The alkanolamine may be one or more selected from diisopropanolamine, monoethanolamine, diethanolamine, triethanolamine, N-methylmonoethanolamine, N-methyldiethanolamine, and N,N-dimethylmonoethanolamine.

Examples of silicates include one or more selected from sodium silicate and potassium silicate, and more specifically, one or more selected from sodium metasilicate, sodium orthosilicate, sodium silicate No. 1, sodium silicate No. 2, sodium silicate No. 3, sodium silicate No. 4, potassium silicate 1K, and potassium silicate 2K.

From the viewpoint of improving the bactericidal properties based on the improved permeability of component (a) to bacteria present inside the cleaning aid, component (c) is preferably one or more selected from ethanol, propylene glycol, benzyl alcohol, methylpropylene glycol, phenoxyethanol, butyl diglycol, phenyl diglycol, diisopropanolamine, and sodium silicate, more preferably one or more selected from ethanol, propylene glycol, benzyl alcohol, methylpropylene glycol, phenoxyethanol, butyl diglycol, and phenyl diglycol, and even more preferably one or more selected from ethanol, methylpropylene glycol, phenoxyethanol, and butyl diglycol.

<Composition, etc.>
From the viewpoint of the bactericidal effect, the bactericidal composition of the present invention contains component (a) in an amount of 0.0001 mass % or more, preferably 0.001 mass % or more, more preferably 0.1 mass % or more, even more preferably 0.2 mass % or more, still more preferably 0.5 mass % or more, and 10 mass % or less, preferably 5 mass % or less, more preferably 3 mass % or less.
In the present invention, when component (a1) is included as component (a), the mass of component (a1) is converted to the value of the chlorine salt. When component (a2) is included as component (a), the mass of component (a2) is converted to the value of the sodium salt. When component (a3) is included as component (a), the mass of component (a3) is converted to the value of the acid.

When the fungicide composition of the present invention contains component (a1), the fungicide composition contains component (a1) in an amount of 0.05% by mass or more, preferably 0.1% by mass or more, more preferably 0.2% by mass or more, even more preferably 0.5% by mass or more, and 10% by mass or less, preferably 5% by mass or less, more preferably 3% by mass or less, even more preferably 2% by mass or less, in terms of the fungicide effect.

When the fungicide composition of the present invention contains component (a2), the fungicide composition contains component (a2) in an amount of 0.5% by mass or more, preferably 1% by mass or more, more preferably 2% by mass or more, and 6% by mass or less, preferably 5% by mass or less, more preferably 3% by mass or less, from the viewpoint of the fungicide effect.

When the fungicide composition of the present invention contains component (a3), the fungicide composition contains component (a3) in an amount of 0.5% by mass or more, preferably 0.8% by mass or more, more preferably 1% by mass or more, and 10% by mass or less, preferably 5% by mass or less, more preferably 3% by mass or less, and even more preferably 2% by mass or less, from the viewpoint of the fungicide effect.

When the fungicide composition of the present invention contains component (a4), the fungicide composition contains component (a4) in an amount of 0.0001% by mass or more, more preferably 0.005% by mass or more, more preferably 0.01% by mass or more, and 0.1% by mass or less, preferably 0.05% by mass or less, more preferably 0.01% by mass or less, from the viewpoint of the fungicide effect.

When the fungicide composition of the present invention contains component (a5), the fungicide composition contains component (a5) in an amount of 0.001% by mass or more, more preferably 0.005% by mass or more, more preferably 0.01% by mass or more, and 0.5% by mass or less, preferably 0.1% by mass or less, more preferably 0.05% by mass or less, from the viewpoint of the fungicide effect.

When the fungicide composition of the present invention contains component (a6), the fungicide composition contains component (a6) in an amount of 0.0001% by mass or more, more preferably 0.0005% by mass or more, more preferably 0.001% by mass or more, and 0.1% by mass or less, preferably 0.01% by mass or less, more preferably 0.005% by mass or less, from the viewpoint of the fungicide effect.

From the viewpoint of improving bactericidal activity, the bactericide composition of the present invention contains component (b) in an amount of 0.1% by mass or more, preferably 0.3% by mass or more, more preferably 0.5% by mass or more, even more preferably 1% by mass or more, and preferably 10% by mass or less, more preferably 5% by mass or less, even more preferably 3% by mass or less.

The fungicide composition of the present invention contains component (c) in an amount of 0.1% by mass or more, preferably 1% by mass or more, more preferably 2% by mass or more, and 10% by mass or less, preferably 7% by mass or less, more preferably 5% by mass or less, in order to improve the fungicidal activity.

In the fungicide composition of the present invention, the mass ratio (a)/(b) of the content of the component (a) to the content of the component (b) is, from the viewpoint of the fungicidal effect, preferably 0.0001 or more, more preferably 0.01 or more, even more preferably 0.1 or more, and preferably 50 or less, more preferably 40 or less, even more preferably 30 or less, still more preferably 20 or less, still more preferably 10 or less, still more preferably 5 or less, and still more preferably 3.5 or less.

When the fungicide composition of the present invention contains the component (a1) as the component (a), the mass ratio (a1)/(b) of the content of the component (a1) to the content of the component (b) is, from the viewpoint of the fungicidal effect, 0.1 or more, preferably 0.3 or more, more preferably 0.5 or more, even more preferably 1 or more, still more preferably 2 or more, and preferably 50 or less, more preferably 40 or less, still more preferably 30 or less, still more preferably 20 or less, still more preferably 10 or less, still more preferably 5 or less, still more preferably 3.5 or less.

When the fungicide composition of the present invention contains the component (a2) as the component (a), the mass ratio (a2)/(b) of the content of the component (a2) to the content of the component (b) is, from the viewpoint of the fungicidal effect, preferably 0.1 or more, more preferably 1 or more, even more preferably 2 or more, and preferably 10 or less, more preferably 5 or less, even more preferably 3.5 or less, and even more preferably 3 or less.

When the fungicide composition of the present invention contains the component (a3) as the component (a), the mass ratio (a3)/(b) of the content of the component (a3) to the content of the component (b) is, from the viewpoint of the fungicidal effect, preferably 0.1 or more, more preferably 0.5 or more, even more preferably 1 or more, and preferably 10 or less, more preferably 5 or less, even more preferably 3 or less, and even more preferably 2.5 or less.

When the fungicide composition of the present invention contains the component (a4) as the component (a), the mass ratio (a4)/(b) of the content of the component (a4) to the content of the component (b) is, from the viewpoint of the fungicidal effect, preferably 0.0001 or more, more preferably 0.0002 or more, even more preferably 0.0003 or more, even more preferably 0.0005 or more, even more preferably 0.001 or more, even more preferably 0.01 or more, and preferably 0.1 or less, more preferably 0.05 or less.

When the fungicide composition of the present invention contains the component (a5) as the component (a), the mass ratio (a5)/(b) of the content of the component (a5) to the content of the component (b) is, from the viewpoint of the fungicidal effect, preferably 0.0001 or more, more preferably 0.001 or more, even more preferably 0.005 or more, even more preferably 0.02 or more, and preferably 1 or less, more preferably 0.5 or less, even more preferably 0.1 or less, and even more preferably 0.05 or less.

When the fungicide composition of the present invention contains the component (a6) as the component (a), the mass ratio (a6)/(b) of the content of the component (a6) to the content of the component (b) is, from the viewpoint of the fungicidal effect, preferably 0.0001 or more, more preferably 0.0002 or more, even more preferably 0.0003 or more, even more preferably 0.0005 or more, and preferably 0.1 or less, more preferably 0.01 or less, even more preferably 0.005 or less, and even more preferably 0.001 or less.

In the fungicide composition of the present invention, the mass ratio (c)/(b) of the content of the component (b) to the content of the component (c) is, from the viewpoint of the fungicidal effect, preferably 0.01 or more, more preferably 0.1 or more, even more preferably 1 or more, and preferably 50 or less, more preferably 40 or less, even more preferably 30 or less, even more preferably 25 or less, even more preferably 20 or less, even more preferably 15 or less, even more preferably 10 or less.

From the viewpoint of rinsing performance and cleaning performance, it is preferable that the disinfectant composition of the present invention contains an anionic surfactant as component (d).

Examples of the anionic surfactant of component (d) include one or more selected from alkylbenzenesulfonates, polyoxyalkylene alkyl or alkenyl ether sulfate salts, alkyl or alkenyl sulfate salts, olefinsulfonates, alkanesulfonates, saturated or unsaturated fatty acid salts, alkyl or alkenyl ether carboxylate salts, α-sulfofatty acid salts, N-acylamino acids, mono- or di-phosphate esters, and sulfosuccinate esters.
The carbon number of the alkyl group or alkenyl group of the anionic surfactant is, for example, 8 to 22 carbon atoms, preferably 10 to 16 carbon atoms, and more preferably 12 to 14 carbon atoms. In the polyoxyalkylene group of the anionic surfactant, the oxyalkylene group is preferably one or more groups selected from an oxyethylene group and an oxypropylene group, and is preferably an oxyethylene group. In the polyoxyalkylene group, the average number of moles of the oxyalkylene group added is, for example, 0 to 10, and preferably 1 to 3.
Examples of counter ions of the anionic groups of these anionic surfactants include alkali metal ions such as sodium ion and potassium ion; alkaline earth metal ions such as calcium ion and magnesium ion; ammonium ion; and alkanolamines having 1 to 3 alkanol groups having 2 or 3 carbon atoms (for example, monoethanolamine, diethanolamine, triethanolamine, triisopropanolamine, etc.).

From the viewpoint of rinsing ability and cleaning performance, the component (d) is preferably one or more selected from alkyl or alkenyl sulfate salts, alkanesulfonates, olefinsulfonates, and saturated or unsaturated fatty acid salts.
The alkyl or alkenyl group of the alkyl or alkenyl sulfate salt has 10 or more, preferably 12 or more, and 18 or less, preferably 14 or less, carbon atoms.
The alkyl group of the alkanesulfonate has 10 or more, preferably 12 or more, and 18 or less, preferably 14 or less, carbon atoms.
The olefin moiety of the olefin sulfonate has 10 or more, preferably 12 or more, and 18 or less, preferably 14 or less, carbon atoms.
The number of carbon atoms in the fatty acid portion of the saturated or unsaturated fatty acid salt is 10 or more, preferably 12 or more, and 18 or less, preferably 14 or less.

When the disinfectant composition of the present invention contains component (d), from the viewpoints of rinsability and cleaning performance, the disinfectant composition contains component (d) in an amount of preferably 0.1 mass % or more, more preferably 0.2 mass % or more, even more preferably 0.3 mass % or less, and preferably 10 mass % or less, more preferably 5 mass % or less, even more preferably 3 mass % or less, and still more preferably 2 mass % or less.
In the present invention, the mass of component (d) is expressed as a value converted into a sodium salt.

In order to increase the added value of the product, the fungicide composition of the present invention may contain any of a metal chelating agent, a water-soluble polymer, a fragrance, a colorant, a preservative, an enzyme, a pH adjuster, an antioxidant, etc., within the range that does not impair the effect of the present invention (excluding the above-mentioned components (a) to (d)).

The disinfectant composition of the present invention contains water. That is, the remainder other than the components (a) to (c) and any optional components is water. The disinfectant composition of the present invention contains water in an amount of preferably 50% by mass or more, more preferably 60% by mass or more, even more preferably 70% by mass or more, even more preferably 80% by mass or more, and preferably 99% by mass or less, more preferably 95% by mass or less. It is preferable to use ion-exchanged water, sterilized ion-exchanged water, etc. as the water.

The pH of the disinfectant composition of the present invention at 25°C is preferably 4 or more, more preferably 5 or more, even more preferably 6 or more, and preferably 12 or less, more preferably 11 or less, even more preferably 10 or less, and even more preferably 8 or less, from the viewpoint of substrate damage. The pH is measured by the glass electrode method.

The germicidal composition of the present invention has both high germicidal power and low damage to the substrate of cleaning aids on which bacteria have accumulated.
Therefore, the disinfectant composition of the present invention is suitable for use in disinfecting cleaning aids.
In the present invention, the cleaning aid refers to a cleaning aid used for cleaning hard surfaces such as toilets, bathrooms, kitchens, and washstands, and part or all of the cleaning aid is made of a flexible material such as a brush, sponge, etc. The flexible material such as a brush or sponge may be one or more materials selected from nylon resin, melamine resin, polyester resin, urethane resin, polypropylene resin, vinyl chloride resin, polyethylene terephthalate resin, plant fiber, animal fiber, metal wire, and elastomer resin.
In particular, the disinfectant composition of the present invention is suitable for a cleaning aid used for cleaning hard surfaces in toilets and/or bathrooms, specifically hard surfaces in toilets (walls, floors, toilet bowls, etc.), hard surfaces around the bathroom (walls, floors, bathtubs, etc.), and hard surfaces of products used in the bathroom (bathroom chairs, washbasins, etc.).
Furthermore, the disinfectant composition of the present invention can be suitably used for cleaning aids that are partially or entirely composed of sponges, since the disinfectant composition can penetrate into the sponge and disinfect it.

The bactericidal composition of the present invention is effective against a wide range of gram-positive and gram-negative bacteria, including gram-positive bacteria such as Staphylococcus aureus, Staphylococcus epidermidis, and Bacillus subtilis, and gram-negative bacteria such as Pseudomonas aeruginosa, Serratia marcescens, Escherichia coli, and Methylobacterium mesophilicum. Among these, the bactericidal composition is particularly effective against Staphylococcus aureus and Escherichia coli.

The germicide composition of the present invention is preferably sprayed or applied in droplet or foam form and brought into contact with a cleaning aid, and more preferably sprayed or applied in foam form and brought into contact with a cleaning aid. A spray means can be used for spraying or application. The present invention provides a germicide article in a spray container, which is prepared by filling a container equipped with a sprayer with the germicide composition of the present invention.

In the spray-container disinfectant article of the present invention, the container equipped with a sprayer into which the disinfectant composition of the present invention is filled may be a trigger-type spray container, a manual spray device that does not use a propellant such as a pump-type spray container, or an aerosol that uses a propellant. The container equipped with the sprayer is preferably a trigger-type spray that can spray or apply the contents in the form of droplets or foam, and more preferably a trigger-type spray equipped with a mechanism for spraying the contents in the form of droplets or a mechanism for forming foam (foam-forming mechanism).

When a trigger-type spray having a mechanism for spraying the fungicide composition of the present invention in the form of droplets is used in the spray-bottled fungicide article of the present invention, the nozzle diameter of the spray container containing the composition is preferably 0.1 mm or more, more preferably 0.3 mm or more, and preferably 2 mm or less, more preferably 1 mm or less, so that spraying is easy, the sprayed droplets are not rough, the sprayed droplets are not sprayed in a straight line, and the sprayable area is not extremely narrow.
When a trigger-type sprayer equipped with a mechanism for spraying droplets is used, the disinfectant article in a spray container of the present invention sprays preferably 0.1 ml or more, more preferably 0.3 ml or more, and preferably 5 ml or less, more preferably 2 ml or less of the composition in one operation.

When using a trigger-type spray equipped with a foam-forming mechanism in the disinfectant article in a spray container of the present invention, it is preferable to use one having a spin element and a liquid passage plate with several rod-shaped protrusions installed in a circular space with a diameter of 4 to 8 mm. Here, the spin element is a mechanism that gives a spin to the flow of liquid through the spin element and finally sprays it from the nozzle, and for detailed structure, reference can be made to JP-A-8-332422, FIG. 4(b) of JP-A-8-108102, FIG. 1 of JP-A-2002-68265, etc.

When using a trigger-type sprayer equipped with a foam-forming mechanism, the disinfectant article in a spray container of the present invention sprays preferably 0.5 ml or more, more preferably 1 ml or more, and preferably 30 ml or less, more preferably 15 ml or less, and even more preferably 5 ml or less of the composition in one operation.

The liquid passage plate, another component of the foam-forming mechanism, has preferably 3 to 8 rod-shaped protrusions installed in a circular space with a diameter of 5 to 7 mm, and when the plate is viewed in plan, the rod-shaped protrusions are preferably rectangular with a width of 0.8 to 1.2 mm and a length of 2 to 4 mm. Furthermore, the area occupied by the rod-shaped protrusions in relation to the space excluding the rod-shaped protrusions is preferably 30 area% or more, more preferably 40 area% or more, and preferably 90 area% or less, more preferably 80 area% or less, and even more preferably 70 area% or less. By installing such a liquid passage plate, the adhesion and retention of foam on the vertical surface is improved.

When the disinfectant composition of the present invention is used in a foam form for application to a cleaning aid, the foam specific volume (foam volume (ml) per unit mass (g)) 5 seconds after foam formation of the disinfectant composition of the present invention is preferably 2 ml/g or more, more preferably 3 ml/g or more, even more preferably 5 ml/g or more, and more preferably 20 ml/g or less, even more preferably 18 ml/g or less, and even more preferably 15 ml/g or less, from the viewpoint of improving the efficiency of action due to the expansion of the target area and improving the disinfecting effect based on the improvement of foam adhesion and retention, compared to when the disinfectant composition is applied in liquid form. The foam specific volume can be measured by the method described in the evaluation of the foam specific volume in the Examples.

When the disinfectant composition of the present invention is used in a foam form for application to a cleaning aid, the foam volume reduction rate 5 minutes after foam formation of the disinfectant composition of the present invention is preferably 15% or more, more preferably 20% or more, even more preferably 25% or more, and even more preferably 30% or more, from the viewpoint of the disinfecting performance of the cleaning aid. The foam volume reduction rate 5 minutes after foam formation is calculated from the foam volume 5 seconds after foam formation and the foam volume 5 minutes after foam formation. Specifically, it can be measured by the method described in the evaluation of the foam volume reduction rate in the Examples.

The disinfectant composition of the present invention is preferably one that, when used with a trigger-type sprayer equipped with a foam-forming mechanism, has a foam specific volume (foam volume (ml) per unit mass (g)) 5 seconds after foam formation of preferably 2 ml/g or more, more preferably 3 ml/g or more, even more preferably 5 ml/g or more, more preferably 20 ml/g or less, even more preferably 18 ml/g or less, and even more preferably 15 ml/g or less, and a foam volume reduction rate 5 minutes after foam formation of preferably 15% or more, more preferably 20% or more, even more preferably 25% or more, and even more preferably 30% or more, from the viewpoint of disinfecting performance of the cleaning auxiliary tool.

The container of the disinfectant article in a spray bottle of the present invention can be a commonly used container. For example, it can be obtained from polyethylene, polypropylene, or polyethylene terephthalate as a raw material, and can be manufactured by blow molding or the like. The thickness of the container may differ between the bottom and sides, and is preferably 0.01 to 2 mm, and the container capacity is preferably 100 to 1000 ml. For ease of handling, the amount of disinfectant composition filled into the container is preferably 200 to 500 ml. Furthermore, the liquid is filled while leaving a reasonable space.

[Method of sterilizing cleaning aids]
The present invention relates to a method for sterilizing a cleaning auxiliary tool, which comprises contacting the cleaning auxiliary tool with the sterilizing composition of the present invention.
The method for sterilizing a cleaning aid of the present invention uses the sterilizing composition of the present invention. The preferred embodiments of the composition are the same as those of the sterilizing composition of the present invention described above.
The cleaning aids of interest are the same as those described for the disinfectant composition of the present invention.

In the method for sterilizing a cleaning aid of the present invention, the sterilizing composition is brought into contact with the cleaning aid, particularly with parts of the cleaning aid that are made of flexible materials such as brushes and sponges.
Specifically, the sterilization method includes contacting the cleaning auxiliary tool with the sterilizing composition in an undiluted form, or contacting the cleaning auxiliary tool with the sterilizing composition in an undiluted form, that is, contacting the cleaning auxiliary tool with the sterilizing composition without dilution.Furthermore, the sterilization method includes contacting the cleaning auxiliary tool with the sterilizing composition without dilution.
The term "contacting the disinfectant composition with the cleaning aid without diluting it" means that the disinfectant composition is not contacted with the cleaning aid after being intentionally diluted with water, etc. For example, when the disinfectant composition is contacted with a cleaning aid having water droplets or the like attached thereto, or when water droplets are attached to the cleaning aid after the disinfectant composition is contacted with the cleaning aid, it can be understood that the disinfectant composition is contacted with the cleaning aid without diluting it.
In the present invention, it is preferable to contact the stock solution of the disinfectant composition with the cleaning aid as it is, that is, without changing the composition. After contacting with the cleaning aid, the composition of the disinfectant composition may change. That is, after contacting with the cleaning aid, the composition of the disinfectant composition may be diluted or concentrated.

The sterilization method of the cleaning aid of the present invention is to contact the cleaning aid with the germicide composition for a predetermined time.In addition, in the sterilization method of the cleaning aid of the present invention, from the viewpoint of familiarizing the germicide composition, it is preferable to apply an external force (physical force) such as pressing the cleaning aid onto a hard surface or kneading the cleaning aid with fingers or the like after contacting the germicide composition with the cleaning aid.In addition, after contacting the germicide composition with the cleaning aid, the cleaning aid may be used to clean a hard surface.
After contacting the cleaning aid with the disinfectant composition, if necessary for a predetermined period of time, the cleaning aid is rinsed with water. When rinsing, an external force (physical force) may be applied by hand or the like, or the cleaning aid may simply be rinsed with a water stream.

The method of contacting the cleaning aid with the disinfectant composition is preferably spraying or coating, more preferably spraying in droplet form or coating in foam form, and even more preferably coating in foam form. The method of disinfecting the cleaning aid of the present invention preferably uses the disinfectant article in a spray container of the present invention described above.

In the method for sterilizing a cleaning aid of the present invention, the disinfectant composition is contacted with the cleaning aid, which is the object, in an amount of preferably 0.1 g or ^more , more preferably 0.5 g or more, even more preferably 1 g or more, and preferably 100 g or less, more preferably 50 g or less, even more preferably 10 g or less, per 100 cm2 of surface area of the cleaning aid.

In the method for sterilizing a cleaning aid of the present invention, when the disinfectant composition is applied to the cleaning aid in the form of a foam, the specific foam volume (foam volume (ml) per unit mass (g)) 5 seconds after the disinfectant composition is foamed is preferably 2 ml/g or more, more preferably 3 ml/g or more, even more preferably 5 ml/g or more, and more preferably 20 ml/g or less, even more preferably 18 ml/g or less, and even more preferably 15 ml/g or less, from the viewpoint of improving the efficiency of action due to the expansion of the target area and improving the disinfecting effect based on the improvement of foam adhesion and retention, compared to when the disinfectant composition is applied in liquid form. The specific foam volume can be measured by the method described in the evaluation of the specific foam volume in the Examples.

In the method for sterilizing a cleaning aid of the present invention, when the aforementioned bactericide composition is used in a foam form for application to the cleaning aid, the foam volume reduction rate 5 minutes after foam formation of the bactericide composition of the present invention is preferably 15% or more, more preferably 20% or more, even more preferably 25% or more, and even more preferably 30% or more, from the viewpoint of the bactericidal performance of the cleaning aid. The foam volume reduction rate 5 minutes after foam formation is calculated from the foam volume 5 seconds after foam formation and the foam volume 5 minutes after foam formation. Specifically, it can be measured by the method described in the evaluation of the foam volume reduction rate in the examples.

In the method for sterilizing a cleaning aid of the present invention, the sterilizing composition is contacted with the cleaning aid for preferably 1 second or more, more preferably 30 seconds or more, even more preferably 60 seconds or more, even more preferably 3 minutes or more, even more preferably 5 minutes or more from the viewpoint of sterilizing effect, and preferably 120 minutes or less, more preferably 60 minutes or less from the viewpoint of substrate damage. In this case, the start of contact may be the time when the composition first contacts the cleaning aid. The predetermined time may be within this range.
The temperature of the disinfectant composition when it is brought into contact may be room temperature, for example, 10°C or higher and 30°C or lower.

The components used in the examples and comparative examples are shown below.
<Component (a)>
Lauryl trimethyl ammonium chloride: component (a1), a compound in which, in the general formula (a11), R ^11a is an alkyl group having 12 carbon atoms, R ^12a , R ^13a and R ^14a are methyl groups, and X ⁻ is a chloride ion, product name: Courtamine 20W, manufactured by Kao Corporation. Stearyl trimethyl ammonium chloride: component (a1), a compound in which, in the general formula (a11), R ^11a is an alkyl group having 18 carbon atoms, R ^12a , R ^13a and R ^14a are methyl groups, and X ⁻ is a chloride ion, product name: Courtamine 86W, manufactured by Kao Corporation. Didecyl dimethyl ammonium chloride: component (a1), a compound in which, in the general formula (a11), R ^11a is an alkyl group having 10 carbon atoms, R ^12a is an alkyl group having 10 carbon atoms, R ^13a and R ^14a are methyl groups, and X A compound in which ^- is a chloride ion, product name: Courtamine D10, manufactured by Kao Corporation; benzalkonium chloride: component (a1), in which in the general formula (a12), R ^15a is an alkyl group having 12 to 16 carbon atoms, R ^16a and R ^17a are methyl groups, and X ^- is a chloride ion; product name: Sanisol B-50, manufactured by Kao Corporation; benzyldecyl dimethyl ammonium chloride: component (a1), in which in the general formula (a12), R ^15a is an alkyl group having 10 carbon atoms, R ^16a and R ^17a are methyl groups, and X ^- is a chloride ion; benzyldodecyl dimethyl ammonium chloride, manufactured by Sigma-Aldrich: component (a1), in which in the general formula (a12), R ^15a is an alkyl group having 12 carbon atoms, R ^16a and R ^17a are methyl groups, and X a compound in which ^- is a chloride ion, benzyltetradecyldimethylammonium chloride (a1), manufactured by Tokyo Chemical Industry Co., Ltd.; a compound in which, in general formula (a12), R ^15a is an alkyl group having 14 carbon atoms, R ^16a and R ^17a are methyl groups, and X ^- is a chloride ion, sodium hypochlorite (a2), manufactured by Tokyo Chemical Industry Co., Ltd.; sulfamic acid (a3), manufactured by FUJIFILM Wako Pure Chemical Co., Ltd.; silver compound (a4), manufactured by FUJIFILM Wako Pure Chemical Co., Ltd.; trade name "CF-01", manufactured by MGC WoodChem Co., Ltd.
-ε-polylysine: component (a5), manufactured by JNC Corporation, trade name "Polylysine"
Polyhexamethylene biguanide hydrochloride: component (a6), product name: Proxel IB, manufactured by Lonza Japan Co., Ltd.

<Component (b)>
Lauramidopropyl betaine: component (b1), a compound in which, in the general formula (b12), R ^14b is an alkyl group having 12 carbon atoms, A is -CONH-, R ^15b is an alkylene group having 3 carbon atoms, r is 1, R ^16b and R ^17b are methyl groups, R ^18b is a methylene group, and B is ^-COO- , product name: Amphitol 20AB, manufactured by Kao Corporation; Lauryl dimethylamine oxide: component (b1), a compound in which, in the general formula (b11), R ^11b is an alkyl group having 12 carbon atoms, R ^12b and R ^13b are methyl groups, q = 0, and p = 0, product name: Amphitol 20N, manufactured by Kao Corporation; Alkyl glycoside: component (b2), a compound in which, in the general formula (b22), R ^21b is an alkyl group having 8 to 16 carbon atoms, p is 0, and q is 1.4; product name: Plantacare 2000UP, manufactured by BASF Ltd.; 2-ethylhexyl glyceryl ether: component (b2); manufactured by Kao Corporation; polyoxyethylene (7) lauryl ether: component (b2); the number in parentheses is the average number of moles of oxyethylene groups added; product name: Emulgen 108, manufactured by Kao Corporation

<Component (c)>
Ethanol: manufactured by Japan Alcohol Sales Co., Ltd. Propylene glycol: manufactured by Tokyo Chemical Industry Co., Ltd. Methylpropylene glycol: manufactured by Nippon Nyukazai Co., Ltd. Phenoxyethanol: manufactured by Tokyo Chemical Industry Co., Ltd. Butyl diglycol: manufactured by Nippon Nyukazai Co., Ltd. Benzyl alcohol: manufactured by Tokyo Chemical Industry Co., Ltd. Phenyl diglycol: manufactured by Tokyo Chemical Industry Co., Ltd. Sodium silicate: manufactured by Fuji Chemical Co., Ltd. Diisopropanolamine: manufactured by Tokyo Chemical Industry Co., Ltd.

<Component (d)>
Sodium lauryl sulfonate: manufactured by Tokyo Chemical Industry Co., Ltd. Sodium lauryl sulfate: product name: EMAL 10G, manufactured by Kao Corporation Sodium coconut oil fatty acid: product name: Lunac L-55, manufactured by Kao Corporation

[Preparation of fungicide composition]
Using the components shown in Tables 1 to 3, disinfectant compositions having the compositions shown in Tables 1 to 3 were prepared by the method described below. To obtain the disinfectant compositions in Tables 1 to 3, first, components (a) to (d) and other components were added to ion-exchanged water in the amounts shown in Tables 1 to 3, and dissolved at room temperature (25°C). After blending, hydrochloric acid and/or sodium hydroxide were added as a pH adjuster to adjust the pH at 25°C to the values shown in Tables 1 to 3. The pH was measured by a glass electrode method.
The contents of each compounded ingredient in Tables 1 to 3 are all effective amounts.

<Example 1 and Comparative Example 1>
[Bactericidal test method for toilet cleaning aids]
A loopful of Staphylococcus aureus (strain NBRC12732) was transferred to a tryptic soy agar plate and cultured at 37±1°C for 18-24 hours. A loopful of this cultured bacteria was transferred to a new tryptic soy agar plate and cultured at 37±1°C for 18-24 hours. The cultured test bacteria were taken with a loopful into a round-bottom test tube containing 20 ml of physiological saline with 5 g of sterilized glass beads (3-5 mm) added, and the bacteria were uniformly suspended to prepare a bacterial solution. The prepared bacterial solution was adjusted to OD600=0.1 (approximately 1.0× ¹⁰⁹ cfu/ml) using a spectrophotometer, and this was used as the test bacterial solution.
A toilet cleaning aid (brush type: KAKU toilet brush, made of polypropylene resin, manufactured by LEC Co., Ltd.; sponge type: MM toilet brush B, made of nylon resin, manufactured by Teramoto Co., Ltd.) was placed in a sterilized stomacher bag and inoculated with 50 ml of test bacteria liquid. The stomacher bag was rubbed more than 20 times so that the test bacteria liquid was evenly and thoroughly soaked into the toilet cleaning aid, and then the toilet cleaning aid was thoroughly drained and left to stand on a petri dish. 1 ml of 0.12 (w/v)% nutrient medium was sprayed evenly over the entire toilet cleaning aid using a small spray container to inoculate the dirt, and the toilet cleaning aid was left to stand at 25 ± 1 ° C. for 20 minutes. Each of the disinfectant compositions listed in Tables 1 and 2 was filled into a spray discharge container (a container of the product of Toilet Magiclean Deodorizing and Cleaning Spray was used, manufactured by Kao Co., Ltd.), and 10 ml of the disinfectant composition was applied in foam form to the toilet cleaning aid that had been inoculated with the test bacteria and dirt and left to stand for 20 minutes. Next, to ensure that the disinfectant composition was evenly and thoroughly absorbed into the toilet cleaning aid, the aid was pressed against a ceramic plate tilted at about 30 degrees and rubbed thoroughly for 30 seconds, after which it was left to stand on a petri dish for 5 minutes.
The toilet cleaning aids inoculated with the disinfectant composition and left to stand for 5 minutes were transferred to sterilized stomacher bags, 50 ml of inactivator was added to the stomacher bags containing the toilet cleaning aids inoculated with the disinfectant composition, and the bags were kneaded by hand 50 times or more to extract bacteria from the toilet cleaning aids. The concentration of bacteria in the extracted inactivation solution was counted by pour culture method.
The same procedure was carried out using a 0.05 (w/v)% polysorbate 80 aqueous solution instead of the disinfectant composition as a control procedure, and the logarithmic difference in the number of bacteria compared to the control procedure using the inactivation solution was calculated and used as an index of disinfection performance according to the following criteria. It was found that, for the compositions shown in Tables 1 and 2, sponge-type toilet cleaning aids tend to be less effective at disinfecting than brush-type toilet cleaning aids, so the tests described below were only performed with sponge-type toilet cleaning aids. Tables 1 and 2 show the results of the disinfection effect of the sponge-type toilet cleaning aids. It can be said that the higher the score, the better the disinfection effect.
5 points: logarithmic difference in the number of bacteria is 3.5 or more 4 points: logarithmic difference in the number of bacteria is 2.5 or more and less than 3.5 3 points: logarithmic difference in the number of bacteria is 2.0 or more and less than 2.5 2 points: logarithmic difference in the number of bacteria is 1.0 or more and less than 2.0 1 point: logarithmic difference in the number of bacteria is less than 1.0

[Method for measuring specific foam volume]
The mass (g) of a plastic 200 ml graduated cylinder with an inner diameter of 3.7 cm was measured using a two-digit balance (a). Each germicide composition listed in Tables 1 and 2 was filled into a spray-dispensing container (a container for the product Toilet Magiclean deodorizing and cleaning spray, manufactured by Kao Corporation), and each germicide composition in Tables 1 and 2 was discharged from the spray-dispensing container into a 200 ml graduated cylinder by pulling the trigger 10 times to be discharged in the form of foam. 5 seconds after the discharge, the mass (g) of the 200 ml graduated cylinder and the mixture of foam and liquid was measured using a two-digit balance (b), and the volume (ml) of the foam phase excluding the liquid phase portion of the mixture of foam and liquid in the graduated cylinder was measured (c). The foam specific volume of each germicide composition was calculated using the following formula. The results are shown in Tables 1 and 2. The measurement of the foam specific volume was performed in an environmental control room adjusted to 25 ° C.
Foam specific volume (ml/g) = (c)/{(b)-(a)}

[Method for measuring foam volume reduction rate]
The mixture of foam and liquid prepared by the above [Method for measuring specific foam volume] was left to stand for 5 minutes, and the volume (ml) of the foam phase excluding the liquid phase after 5 minutes was measured (d). The foam volume reduction rate after 5 minutes from discharge was calculated using the following formula. The results are shown in Tables 1 and 2. The measurement of the foam volume reduction rate was carried out in an environmentally controlled room adjusted to 25°C.
Foam volume reduction rate (%) = 100-{(d)/(c)}×100

[Method for measuring substrate damage]
Each of the disinfectant compositions shown in Tables 1 and 2 was filled into a spray-dispensing container (a product container for Toilet Magiclean deodorizing and cleaning spray, manufactured by Kao Corporation), and 10 ml of the disinfectant composition was applied in foam form from the spray-dispensing container to a toilet cleaning aid (brush type: KAKU toilet brush, made of polypropylene resin, manufactured by Reck Co., Ltd.), and the appearance of the toilet cleaning aid after 24 hours was visually confirmed according to the following criteria. The results are shown in Tables 1 and 2.
○: No change or discoloration in appearance ×: Change or discoloration in appearance

Example 2
[Bactericidal test method for bathroom cleaning aids]
A loopful of Staphylococcus aureus (strain NBRC12732) was transferred to a tryptic soy agar plate medium and cultured at 37±1° C. for 18 to 24 hours. A loopful of this cultured bacteria was transferred to a new tryptic soy agar plate medium and cultured at 37±1° C. for 18 to 24 hours. The cultured test bacteria were collected with a loopful into a round-bottom test tube containing 20 ml of physiological saline to which 5 g of sterilized glass beads (3-5 mm) had been added, and the bacteria were uniformly suspended to prepare a bacterial solution. A nutrient medium concentrate in an amount to give a final concentration of 0.3 (w/v)% and a hard water concentrate in an amount to give a final concentration of 3° DH were added to a sterilized container and mixed well, and the above-mentioned bacterial solution was added to the container in an amount to give a final concentration of 7.0 x ¹⁰ to 7.0 x ¹⁰ cfu/ml. Each component was adjusted to the specified final concentration using high-pressure steam sterilized or filtered sterilized water, and this was used as the test bacterial solution.
A bathroom cleaning aid (Polybath Sponge BL161, made of polyurethane foam, manufactured by Aisen Co., Ltd., processed to a diameter of 24 mm x thickness of 30 mm) was placed in a sterilized screw-top bottle, and 0.5 ml of the test bacteria liquid was inoculated into the bathroom cleaning aid. The test bacteria liquid was rubbed more than 10 times with a sterilized test piece rod so that it was evenly and thoroughly soaked into the bathroom cleaning aid, and the lid was placed in an incubator at 25 ± 1 ° C. for 1 hour. Each of the germicide compositions listed in Table 3 was filled into a spray discharge container (a container of the Bath Magiclean SUPERCLEAN product was used, manufactured by Kao Corporation), and 0.5 ml of each germicide composition was applied to the bathroom cleaning aid in a foam form. The germicide composition was rubbed more than 100 times with a sterilized test piece rod so that it was evenly and thoroughly soaked into the bathroom cleaning aid, and the lid was placed in an incubator at 25 ± 1 ° C. and left for 5 minutes. 20 ml of the inactivator (SCDLP medium) was added to a screw-cap bottle containing a bathroom cleaning aid inoculated with the disinfectant composition, and the bottle was rubbed with a sterilized test piece stick more than 20 times to extract bacteria from the test piece (bacterial extract). Exactly 1.0 ml of the bacterial extract was taken with a sterilized pipette, added to a test tube containing 9.0 ml of dilution solution, and thoroughly mixed. This operation was repeated to prepare 10-fold serial dilutions, and the number of live bacteria was counted by the pour culture method.
The same procedure was carried out using a 0.05 (w/v)% aqueous solution of polysorbate 80 instead of the disinfectant composition as a control, and the logarithmic difference in the number of bacteria from the control procedure using an inactivating agent was calculated and used as an index of disinfection performance according to the following criteria. The results are shown in Table 3. A higher score indicates a more excellent disinfection effect.
5 points: logarithmic difference in the number of bacteria is 3.5 or more 4 points: logarithmic difference in the number of bacteria is 2.5 or more and less than 3.5 3 points: logarithmic difference in the number of bacteria is 2.0 or more and less than 2.5 2 points: logarithmic difference in the number of bacteria is 1.0 or more and less than 2.0 1 point: logarithmic difference in the number of bacteria is less than 1.0

[Method for measuring specific foam volume]
The mass (g) of a plastic 200 ml graduated cylinder with an inner diameter of 3.7 cm was measured with a lower double-digit balance (a). Each germicide composition listed in Table 3 was filled into a spray discharge container (using a container of the product of Bath Magiclean SUPERCLEAN, manufactured by Kao Corporation), and the germicide composition in Table 3 was discharged from the spray discharge container into a 200 ml graduated cylinder by pulling the trigger 10 times to be discharged in the form of foam. 5 seconds after the discharge, the mass (g) of the 200 ml graduated cylinder and the mixture of foam and liquid was measured with a lower double-digit balance (b), and the volume (ml) of the foam phase excluding the liquid phase part of the mixture of foam and liquid in the graduated cylinder was measured (c). The foam specific volume of the germicide composition was calculated using the following formula. The results are shown in Table 3. The measurement of the foam specific volume was performed in an environmental control room adjusted to 25 ° C.
Foam specific volume (ml/g) = (c)/{(b)-(a)}

[Method for measuring foam volume reduction rate]
The mixture of foam and liquid prepared by the above [Method for measuring specific foam volume] was left to stand for 5 minutes, and the volume (ml) of the foam phase excluding the liquid phase after 5 minutes was measured (d). The foam volume reduction rate after 5 minutes from discharge was calculated using the following formula. The results are shown in Table 3. The measurement of the foam volume reduction rate was carried out in an environmentally controlled room adjusted to 25°C.
Foam volume reduction rate (%) = 100-{(d)/(c)}×100

[Method for measuring substrate damage]
Each of the disinfectant compositions shown in Table 3 was filled into a spray-dispensing container (a container of the Bath Magiclean SUPER CLEAN product, manufactured by Kao Corporation), and 10 ml of the disinfectant composition was applied in foam form from the spray-dispensing container to a bathroom cleaning aid (Polybath Sponge BL161, polyurethane foam, manufactured by Aisen Co., Ltd., diameter 24 mm x thickness 30 mm) that had been processed into a bathroom cleaning aid. After 24 hours, the appearance of the bathroom cleaning aid was visually confirmed according to the following criteria. The results are shown in Table 3.
○: No change or discoloration in appearance ×: Change or discoloration in appearance

<Composition Example>
Formulation examples of the disinfectant composition of the present invention suitable for toilet cleaning aids are shown in Tables 4 and 5, and formulation examples of the disinfectant composition of the present invention suitable for bathroom cleaning aids are shown in Tables 6 and 7. All of the formulation examples can achieve both high disinfecting power and low damage to the substrate against cleaning aids on which bacteria have accumulated.

In the table, the components other than those mentioned above are as follows.
<Component (a)>
Didecyldimethylammonium chloride: manufactured by Fujifilm Wako Pure Chemical Industries, Ltd. Benzethonium chloride: manufactured by Tokyo Chemical Industry Co., Ltd. <Component (c)>
Benzyl alcohol: manufactured by Tokyo Chemical Industry Co., Ltd. (component (d))
・Sodium α-olefin sulfonate: manufactured by Kao Corporation ・Sodium di(2-ethylhexyl) sulfosuccinate: manufactured by Tokyo Chemical Industry Co., Ltd. ・Sodium di(2-propylheptyl) sulfosuccinate: manufactured by Kao Corporation
・ Sodium polyoxyethylene (2) lauryl ether sulfate: manufactured by Kao Corporation <Other ingredients>
Citric acid: manufactured by Tokyo Chemical Industry Co., Ltd. EDTA: tetrasodium ethylenediaminetetraacetate, manufactured by Chubu Cherest Co., Ltd. Hydrophilic polymer: sulfobetaine methacrylate/methacryloyloxyethyl dimethylethylammonium ethyl sulfate copolymer, manufactured by Kao Corporation Fragrance: manufactured by Kao Corporation

Claims (13)

A disinfectant composition comprising: 0.001% by mass or more and 10% by mass or less of the following component (a); 0.1% by mass or more of the following component (b); 0.1% by mass or more and 10% by mass or less of the following component (c); and water.
Component (a): a disinfectant; Component (b): one or more surfactants selected from amphoteric surfactants and nonionic surfactants; Component (c): a penetrating agent The fungicide composition according to claim 1, wherein component (a) is one or more selected from quaternary ammonium salts, oxidizing agent-based fungicides, sulfamic acid or its salts, metal-based fungicides, polyamino acids, and polyhexamethylene biguanide or its salts. The fungicide composition according to claim 1 or 2, wherein the mass ratio (a)/(b) of the content of the (a) component to the content of the (b) component is 0.0001 or more and 50 or less, and the mass ratio (c)/(b) of the content of the (b) component to the content of the (c) component is 0.01 or more and 50 or less. The disinfectant composition according to claim 1 or 2, wherein component (c) is one or more selected from alcohols, glycol ethers, alkanolamines, and silicates. The disinfectant composition according to claim 1 or 2, further comprising an anionic surfactant as component (d). The fungicide composition according to claim 1 or 2, wherein the fungicide composition has a foam specific volume of 1 ml/g or more and 15 ml/g or less 5 seconds after foam formation using a trigger-type spray equipped with a foam forming mechanism, and a foam volume reduction rate of 10% or more 5 minutes after foam formation. The disinfectant composition according to claim 1 or 2, which is for use in a cleaning aid. The disinfectant composition according to claim 7, wherein the cleaning aid is for use in a toilet and/or a bathroom. A disinfectant product in a spray container, comprising a container equipped with a sprayer, and the disinfectant composition according to claim 1 or 2 filled in the container. A method for sterilizing a cleaning aid, comprising contacting the cleaning aid with the disinfectant composition according to claim 1 or 2. The method for sterilizing a cleaning aid according to claim 10, wherein the cleaning aid is used in a toilet and/or a bathroom. The method for sterilizing a cleaning aid according to claim 10, wherein the cleaning aid is made in part or in whole from a flexible material. The method for sterilizing a cleaning aid according to claim 10, wherein the disinfectant composition is brought into contact with the cleaning aid in the form of foam having a foam specific volume of 1 ml/g or more and 15 ml/g or less 5 seconds after foam formation and a foam volume reduction rate of 10% or more after 5 minutes.