JP4980892B2 - Chemical injection device - Google Patents

Description

  The present invention relates to a chemical injection device that injects a chemical into a subject by relatively moving a cylinder member and a piston member of the chemical syringe, and in particular, a chemical injection device in which an injection execution head to which a chemical syringe is attached rotates in a vertical direction. About.

At present, CT (Computed) is used as a fluoroscopic imaging apparatus for capturing a fluoroscopic image of a subject.
Tomography) scanner, MRI (Magnetic Resonance Imaging) equipment, PET (PositronEmission)
Tomography) apparatus, ultrasonic diagnostic apparatus, CT angio apparatus, MRA (MR Angio) apparatus, and the like.

  When using the fluoroscopic imaging apparatus as described above, a chemical solution such as a contrast medium or physiological saline may be injected into a subject, and a chemical solution injection apparatus that automatically executes this injection has also been put into practical use. Such a chemical injection device has, for example, a syringe drive mechanism including a drive motor and a slider mechanism, and the chemical syringe is detachably attached to an injection execution head in which the syringe drive mechanism is built.

  The chemical solution syringe has a structure in which a piston member is slidably inserted into a cylinder member, and there are a prefilled type and a refill type. The pre-filled type chemical syringe is shipped in a state where the cylinder member is filled with the chemical solution and the whole is sealed with a packing material, and the refill type chemical syringe is filled with a desired chemical solution by the user.

  When injecting a drug solution from a prefilled type drug solution syringe to a subject, for example, a drug solution syringe connected with an injection tube is attached to an injection execution head in an injection posture with the tip positioned below the end. In this injection posture, since the tip of the chemical syringe to which the injection tube is connected is also positioned below, the air bubbles mixed in the chemical when the injection tube is connected are positioned at the end of the chemical syringe.

  Therefore, the injection execution head is manually rotated together with the chemical solution syringe, and a preparation posture is established in which the tips of the chemical solution syringe and the injection execution head are positioned upward. In this preparation posture, the air bubbles mixed in the chemical liquid are located at the tip of the chemical liquid syringe. When the syringe drive mechanism is operated in this state and the piston member is press-fitted into the cylinder member to a predetermined position, the air bubbles are mixed with a small amount of chemical liquid. It is discharged from the inside of the drug solution syringe and the injection tube.

  Therefore, in this state, the injection tube is connected to the blood vessel of the subject, and the injection execution head is manually rotated together with the chemical syringe to be in the injection posture. When the syringe drive mechanism is operated in this state and the piston member is press-fitted into the cylinder member, the chemical solution in the chemical solution syringe is injected into the subject from the injection tube. At this time, even if minute bubbles are mixed in the chemical solution of the chemical syringe, since the bubbles are located at the end of the chemical syringe, they are not mixed into the chemical solution injected into the subject from the tip.

  In addition, when injecting a chemical solution from a refill type chemical solution syringe to a subject, for example, a large chemical solution tank filled with the chemical solution is connected to the chemical solution syringe with a dedicated suction tube, and the chemical solution syringe is injected in an injection posture. Mounted on the head. In this state, the injection execution head is manually rotated to the ready posture, the syringe drive mechanism is operated, and the piston member is pulled out from the cylinder member to a predetermined position.

  Then, since the chemical solution in the chemical solution tank is drawn into the chemical solution syringe from the suction tube, the chemical solution tank is removed together with the suction tube from the chemical solution syringe after the completion of the suction. In this state, the injection tube is connected to the chemical syringe, and the syringe drive mechanism is operated to a predetermined position so that the air bubbles mixed in the chemical solution of the chemical syringe are discharged. Thereafter, the same as in the case of the prefilled type An injection operation is performed.

  Since the refill type chemical syringe as described above is shipped with the piston member positioned near the rear end of the cylinder member, the positional relationship of the piston member relative to the cylinder member is a new prefilled type chemical syringe. Is the same. Moreover, since chemical solutions such as physiological saline and contrast media are generally colorless and transparent, new refill type and prefilled type chemical syringes may not be distinguished at a glance.

  For this reason, there is a possibility that a new refill type chemical syringe is attached to the chemical injection device and that the chemical syringe is mistaken as a prefilled type and air is injected into the subject. Therefore, in order to eliminate this possibility, it is determined whether the installed chemical syringe is a prefilled type or a refill type, and in the case of the refill type, a piston member is automatically press-fitted so that a chemical solution inhalation can be started. (For example, refer to Patent Document 1).

Further, as described above, in the chemical solution injection device in which the injection execution head rotates in the vertical direction, the piston member is moved back and forth when the tip of the chemical solution syringe is positioned upward, and only forward when the tip is positioned downward. Thus, there is also a proposal of inhaling a chemical solution after discharging air from the chemical solution syringe to the chemical solution tank and injecting the chemical solution from the chemical solution syringe to the subject (for example, see Patent Document 2).
JP 2003-70911 A JP-T-2004-501737

  However, in the chemical injection device of Patent Document 1 described above, it is possible to prevent the operation of the chemical injection from being performed with a new refill type chemical syringe, but the refill type chemical syringe or the new prefilled type in which the chemical liquid has been inhaled can be prevented. Therefore, it is not possible to prevent the liquid medicine from being injected into the subject from the liquid medicine syringe in which the air bubble removal has not been completed.

  Moreover, in the chemical | medical solution injection apparatus of the patent document 2 mentioned above, since operation | movement of the injection | pouring execution head is only controlled corresponding to an attitude | position, it is difficult to prevent an improper operation | movement reliably reliably in fact. For example, in general, when the injection execution head is in the injection posture, not only the injection of the chemical solution from the chemical solution syringe to the subject but also the attachment / detachment of the chemical solution syringe is executed.

  For this reason, if the injection execution head can be operated in the injection posture simply, there is a possibility that the chemical solution may be injected into the subject from the chemical solution syringe in which bubble elimination has not been completed. In particular, when the drug solution syringe is a refill type, air may be injected into the subject from the drug solution syringe that has not inhaled the drug solution.

  Therefore, in order to solve the above-described problems, the chemical injection device proposed by the applicant of the present application can only perform bubble elimination and chemical solution inhalation operations when the attachment of the chemical syringe is detected. When the operator visually confirms the removal of bubbles and manually operates the dedicated release switch, it is also possible to inject the chemical solution. Will not be injected. However, in this case, a dedicated release switch or the like needs to be added to the chemical solution injector, and the work load such as visual inspection and switch operation increases.

  The present invention has been made in view of the above-described problems, and without requiring the addition of a release switch or an increase in the work load, the chemical solution injection is performed with a chemical syringe that has not completed bubble elimination or chemical solution suction. It aims at providing the chemical | medical solution injection device which can prevent being performed.

  The first chemical liquid injector of the present invention relatively moves the cylinder member and the piston member of the chemical syringe in which the piston member is slidably inserted from the opening at the end of the cylinder member having the conduit portion formed at the tip. A chemical liquid injection device for injecting a chemical liquid from a chemical syringe to a subject, an injection execution head, a syringe drive mechanism, a chemical liquid injection means, an initial setting means, a manual operation means, an operation drive means, a completion detection means, an injection control means, have.

  An injection execution head is detachably mounted with a chemical solution syringe, and a syringe drive mechanism relatively moves a cylinder member and a piston member of the chemical solution syringe mounted on the injection execution head. The medicinal solution injection means press-fits the piston member into the cylinder member by the operation control of the syringe drive mechanism for injecting medicinal solution from the medicinal solution syringe to the subject, and the initial setting means initializes the medicinal solution injection means to be inoperable. . The manual operation means accepts an input operation for causing the syringe drive mechanism to execute, in real time, bubble elimination for removing bubbles from the chemical solution of the chemical syringe in real time, and the operation drive means supports the input operation to the manual operation means in real time. Then, the syringe drive mechanism is operated. The completion detection means detects the completion of bubble elimination based on at least one of the movement distance and the movement position of the syringe drive mechanism, and the injection control means makes the chemical solution injection means operable when the completion of bubble removal is detected. .

  Therefore, in the first chemical liquid injector of the present invention, the chemical liquid injection cannot be executed in the initial state, and when the bubble elimination is performed on the chemical syringe manually from the initial state, the completion of the bubble exclusion is detected and the chemical liquid is detected. Only injection can be executed.

  The second and third chemical liquid injectors of the present invention are chemical liquid injectors that inject a chemical liquid from a chemical liquid tank into a chemical syringe by relatively moving a cylinder member and a piston member of the chemical liquid syringe and then injecting the liquid into a subject. In the second liquid injector, the injection execution head is detachably mounted with a refill type liquid syringe that sucks the liquid from an external liquid tank, and the manual operation means transfers at least the liquid from the liquid tank to the liquid syringe. An input operation for causing the syringe drive mechanism to execute inhalation of the medical solution to be inhaled in real time is received. The completion detection means detects the completion of the chemical liquid inhalation based on at least one of the movement distance and the movement position of the syringe drive mechanism, and the injection control means makes the chemical liquid injection means operable when the completion of the chemical liquid inhalation is detected. .

  Therefore, in the second chemical liquid injector of the present invention, the chemical liquid injection cannot be executed in the initial state, and when the chemical liquid suction is executed to the chemical syringe manually from the initial state, the completion of the chemical liquid suction is detected and the chemical liquid is detected. Only injection can be executed.

  In the third chemical liquid injector of the present invention, the manual operation means executes in real time at least a chemical liquid inhalation for inhaling the chemical liquid from the chemical liquid tank into the chemical liquid syringe and a bubble elimination for excluding bubbles from the chemical liquid in the chemical syringe in the syringe drive mechanism. The completion detection means individually detects the completion of the chemical solution inhalation and the bubble elimination by at least one of the movement distance and the movement position of the syringe drive mechanism, and the injection control means When the completion of the removal is detected in order, the chemical solution injection means can be operated.

  Therefore, the third chemical injection device according to the present invention cannot perform the chemical injection in the initial state, and when the chemical injection and the bubble elimination are sequentially performed in the chemical syringe from the initial state by manual operation, Completion of bubble elimination is detected individually, and only chemical liquid injection can be executed.

  In the fourth liquid injector of the present invention, the cylinder member and the piston member of the liquid syringe, in which the piston member is slidably inserted from the opening at the end of the cylinder member having the conduit portion formed at the tip, are moved relative to each other. Thus, it is a chemical solution injection device that injects at least a chemical solution from a chemical solution syringe to a subject, and also has a syringe discrimination means.

  In the fourth chemical injection device of the present invention, the injection execution head can select and remove the prefilled type chemical syringe filled with the chemical from the beginning and the refill type chemical syringe that sucks the chemical from the external chemical tank. Syringe discriminating means discriminates whether the liquid syringe attached to the injection execution head is a prefilled type or a refill type, and the injection control means detects completion of bubble elimination when the prefilled type is discriminated. Then, when the refill type is determined as the state in which the chemical solution injection means can be operated, the completion of the chemical solution inhalation and the bubble elimination is detected in order, so that the chemical solution injection means can be operated.

  Therefore, the fourth chemical liquid injection device of the present invention cannot perform chemical liquid injection in the initial state, and in the prefilled type chemical liquid syringe, when the bubble elimination is executed manually from the initial state, the completion of the bubble elimination is not completed. In the refill type liquid syringe, when the liquid inhalation and the bubble elimination are sequentially executed by manual operation from the initial state, the completion of the liquid inhalation and the bubble elimination is individually performed. It will be detected and it will be in the state which can perform only chemical | medical solution injection | pouring.

  The various means referred to in the present invention need only be formed so as to realize the function. For example, dedicated hardware that exhibits a predetermined function, a data processing apparatus provided with a predetermined function by a computer program It can be realized as a predetermined function implemented in the data processing apparatus by a computer program, a combination thereof, or the like.

  In addition, the various constituent elements referred to in the present invention do not have to be independent of each other, a plurality of constituent elements are formed as one member, and a constituent element is a part of another constituent element. It is also possible that a part of a certain component and a part of another component overlap.

  The first chemical injection device of the present invention cannot perform chemical injection in the initial state, and when bubble elimination is performed on the chemical syringe manually from the initial state, the completion of the bubble exclusion is detected and only chemical injection is performed. By being ready for execution, it is possible to automatically prevent chemical injection from being performed with chemical syringes that have not completed bubble elimination without requiring an additional release switch or an increased work load. it can.

  The second chemical injection device according to the present invention cannot execute chemical injection in the initial state, and when the chemical injection is performed by the manual operation from the initial state, the completion of the chemical injection is detected and only the chemical injection is performed. By being ready for execution, it is possible to automatically prevent chemical injection from being performed with a chemical syringe that has not been inhaled, without requiring an additional release switch or an increased work load. it can.

  In the third liquid injector of the present invention, the liquid injection cannot be performed in the initial state, and when the liquid suction and the bubble elimination are sequentially performed on the liquid syringe by manual operation from the initial state, the liquid suction and the bubble exclusion are performed. And the completion of the individual detection, and only the injection of the chemical solution can be executed, so that the bubble elimination is executed by the chemical syringe in which the chemical solution inhalation is not properly completed, and the chemical solution in which the bubble exclusion is not completed. It is possible to automatically prevent the chemical injection from being performed by the syringe without requiring an additional release switch or an increased work load.

  In the fourth liquid injector of the present invention, the liquid injection cannot be executed in the initial state, and in the prefilled type liquid syringe, when the bubble removal is executed manually from the initial state, the completion of the bubble removal is detected. In the refill type liquid syringe, when the chemical liquid suction and the bubble elimination are sequentially executed from the initial state by manual operation, the completion of the liquid suction and the bubble elimination is individually detected. In the state where only chemical liquid injection can be performed, chemical liquid injection is executed with a prefilled type chemical liquid syringe for which bubble elimination has not been completed, and bubbles are generated with a refill type chemical liquid syringe for which chemical liquid inhalation has not been properly completed. Exclusion is performed, and chemical injection is performed with a refill type chemical syringe that has not completed this bubble exclusion. , It can be automatically prevented without the need for such an increase in the expansion and work burden of the release switch.

It is a typical block diagram which shows the logic structure of the chemical injection device of embodiment of this invention. It is a block diagram which shows the circuit structure of a fluoroscopic imaging system. It is a perspective view which shows the external appearance of a chemical injection device. It is a perspective view which shows the state which attaches a chemical | medical solution syringe with a pressure | voltage resistant cover to the injection execution head of a chemical | medical solution injection device. It is a perspective view which shows the external appearance of a fluoroscopic imaging system. (a) is a side view showing an injection posture of an injection execution head, and (b) is a side view showing a preparation posture. It is a flowchart which shows the first half part of processing operation of a chemical injection device. It is a flowchart which shows a latter half part.

Explanation of symbols

DESCRIPTION OF SYMBOLS 100 Chemical liquid injection apparatus 110 Injection execution head 112 Movable arm which is a head support mechanism 117 Syringe drive mechanism 120 Attachment / detachment detection sensor which is attachment / detachment detection means 122 Inclination detection sensor which is posture determination means 141 Chemical liquid injection means 142 Initial setting means 143 Operation drive means 144 Completion detection means 145 Injection control means 146 Drive restriction means 200 Chemical liquid syringe 210 Cylinder member 212 Conduit portion 220 Piston member 1000 Fluoroscopic imaging system

[Configuration of the embodiment]
An embodiment of the present invention will be described below with reference to the drawings. As shown in FIGS. 1 to 3, a fluoroscopic imaging system 1000 according to an embodiment of the present invention includes a chemical injection device 100, a chemical syringe 200, a CT angio device 400 that is a fluoroscopic imaging device, a pressure-resistant cover 300 that is a cylinder adapter, As will be described in detail later, a contrast medium or the like is injected into a subject (not shown) as a drug solution.

  As shown in FIG. 5, the CT angiography apparatus 400 includes a fluoroscopic imaging unit 401 and an imaging control unit 402 that are imaging execution mechanisms. The fluoroscopic imaging unit 401 and the imaging control unit 402 are connected via a communication network 403. Wired connection. The fluoroscopic imaging unit 401 captures a fluoroscopic image from the subject, and the imaging control unit 402 controls the operation of the fluoroscopic imaging unit 401.

  As shown in FIG. 4, the chemical syringe 200 includes a cylinder member 210 and a piston member 220, and the piston member 220 is slidably inserted into the cylinder member 210. The cylinder member 210 has a cylindrical hollow main body portion 211, and a conduit portion 212 is formed on the closed end surface of the main body portion 211. The end surface of the main body 211 of the cylinder member 210 is opened, and the piston member 220 is inserted into the main body 211 from this opening.

  The pressure-resistant cover 300 also has a cylindrical hollow main body 301, and a through hole 302 is formed in the closed front end surface of the main body 301. The end face of the pressure-resistant cover 300 is opened, and the cylinder member 210 of the chemical syringe 200 is disposed inside the main body 301 from this opening. An annular cover flange 303 is integrally formed on the outer periphery of the end face of the pressure-resistant cover 300. For example, a magnetic body 310 is built in a convex portion below the cover flange 303.

  As shown in FIG. 3, the chemical injection device 100 of the present embodiment includes an injection control unit 101 and an injection execution head 110 that are formed separately, and the injection control unit 101 and the injection execution head 110 are connected to a communication cable 102. Wired connection. The injection execution head 110 is attached to the upper end of the caster stand 111 by a movable arm 112 as a head support mechanism, and a flange holding is attached to the front surface of the head main body 113 so as to detachably hold the pressure-resistant cover 300 together with the chemical syringe 200. A mechanism 114 is formed.

  Since the movable arm 112 pivotally supports the injection execution head 110 so as to be rotatable in the vertical direction, as shown in FIG. 6A, the distal end of the attached chemical syringe 200 is at the end. As shown in FIG. 6 (b), the pouring posture positioned further downward and the preparatory posture positioned above are movably supported.

  As shown in FIG. 4, the flange holding mechanism 114 rotates in the vertical direction at the positions of the left and right ends of the fixed holding member 115 and a semicircular arc shaped fixed holding member 115 fixed to the lower front surface of the head body 113. The cover flange 303 of the pressure-resistant cover 300 is engaged with the fixed holding member 115 from above, and a pair of left and right movable members are mounted on the upper portion of the cover flange 303. The holding member 116 is engaged from above.

  A recess (not shown) is formed in the lower part of the flange holding mechanism 114, and the magnetic body 310 of the cover flange 303 is detachably inserted into the recess. An attachment / detachment detection sensor 120 made of a hall element or the like is built in the recess of the flange holding mechanism 114 as attachment / detachment detection means, and the attachment / detachment detection sensor 120 detects the magnetic body 310. That is, when the chemical syringe 200 is attached to the injection execution head 110 together with the pressure-resistant cover 300, the attachment of the chemical syringe 200 is detected by the attachment / detachment detection sensor 120.

  The injection execution head 110 has a syringe drive mechanism 117 disposed on the front surface located at the center inside the flange holding mechanism 114. The syringe drive mechanism 117 holds the piston member 220 of the chemical syringe 200 and press-fits into the cylinder member 210. To do. The syringe drive mechanism 117 has a drive motor 118 as a drive source, and slides the piston member 220 by a screw mechanism (not shown) or the like.

  The syringe drive mechanism 117 also includes a linear encoder 119, and the linear encoder 119 detects the position of the piston member 220 that the syringe drive mechanism 117 slides. The injection execution head 110 is provided with a sub-touch panel 121 as a manual operation means on the upper front part, and various guidance messages are displayed on the sub-touch panel 121.

  In the chemical injection device 100 of this embodiment, an inclination detection sensor 122 including an acceleration sensor or the like is built in the injection execution head 110 as an attitude determination unit, and the attitude of the injection execution head 110 is determined by the inclination detection sensor 122. That is, since the injection execution head 110 is pivotally supported so as to be rotatable in the vertical direction, as shown in FIGS. 6A and 6B, the injection head is positioned above the injection posture in which the tip is positioned below the end. It is supported so that it can be displaced in the preparation posture. Then, the inclination detection sensor 122 detects, for example, whether the injection execution head 110 is in the injection posture or the preparation posture by detecting the direction of gravity acting on itself.

  The injection execution head 110 as described above is wired to the injection control unit 101, and the control unit 101 controls the operation of the injection execution head 110. For this reason, as shown in FIG. 2, the injection control unit 101 includes a computer unit 130, and is also wired to the imaging control unit 402 of the CT angio apparatus 400 via a communication network 404. The injection control unit 101 includes an operation panel 103, a main touch panel 104, a speaker unit 105, and the like arranged on the front surface of the main body housing 106, and the various devices described above are connected to the computer unit 130.

The computer unit 130 includes a so-called one-chip microcomputer and a CPU (Central
It has hardware such as a processing unit (131), a ROM (Read Only Memory) 132, a RAM (Random Access Memory) 133, and an I / F (Interface) 134. In the computer unit 130, an appropriate computer program is mounted as firmware on an information storage medium such as the ROM 132, and the CPU 131 executes various processing operations corresponding to the computer program.

  As shown in FIG. 1, the liquid injector 100 according to the present embodiment operates as the computer unit 130 corresponds to the computer program installed as described above, so that the liquid injector 141, the initial setting unit 142, the operation Various means such as a drive means 143, a completion detection means 144, an injection control means 145, and a drive restriction means 146 are logically provided.

  The chemical solution injection means 141 corresponds to the function of the CPU 131 controlling the operation of the syringe drive mechanism 117 in response to the computer program stored in the ROM 132 and the input operation to the main touch panel 104, and is for injecting the chemical solution from the chemical solution syringe 200 to the subject. The piston member 220 is press-fitted into the cylinder member 210.

  More specifically, in chemical injection, for example, when injection conditions such as injection speed / time / pressure / volume / pattern are input in advance to the main touch panel 104 by an operator, the injection conditions are stored in the RAM 133 or the like. Data is retained. Then, when the operator inputs the start of injection to the operation panel 103 or the like, the CPU 131 automatically controls the operation of the syringe drive mechanism 117 in accordance with the injection conditions stored, thereby automatically executing a series of chemical injections. Is done.

  The initial setting means 142 corresponds to the function of the CPU 131 controlling the operation of the syringe drive mechanism 117 in response to the computer program and the detection data of the attachment / detachment detection sensor 120. The attachment / detachment detection sensor 120 detects the attachment of the chemical syringe 200. Then, the chemical solution injection means 141 is initially set to be inoperable.

  The operation driving unit 143 corresponds to a function of the CPU 131 controlling the operation of the syringe driving mechanism 117 in response to the computer program and the input data of the sub touch panel 121, and is a sub touch panel that is a manual operation unit after initial setting is completed. The syringe drive mechanism 117 is operated corresponding to the input operation to 121 in real time.

  More specifically, as described above, the chemical syringe 200 includes a prefilled type and a refill type. However, in the chemical injection device 100 of this embodiment, only the refill type chemical syringe 200 is basically used. The chemical solution inhalation in which the chemical solution 200 is inhaled from an external chemical solution tank (not shown) 200 and the bubble elimination in which the bubbles are excluded from the chemical solution of the chemical solution syringe 200 are performed.

  When the chemical solution inhalation is executed, the chemical solution tank is connected to a new empty chemical solution syringe 200 by an intake tube (not shown), and the chemical solution syringe 200 is attached to the injection execution head 110. Then, when a manual operation for inhaling a chemical solution is executed on the sub-touch panel 121 of the injection execution head 110, the syringe drive mechanism 117 is driven in response to the manual operation in real time to execute the inhalation of the chemical solution.

  When bubble elimination is executed, an injection tube (not shown) is connected to the chemical syringe 200 into which the chemical solution has been inhaled as described above, and the operator performs the injection execution head 110 in a ready posture. When a manual operation for removing bubbles is performed on the sub-touch panel 121, the syringe drive mechanism 117 is driven in response to the manual operation in real time, thereby removing the bubbles. For this reason, the operation driving means 143 is in a state in which the bubble removal that causes the piston member 220 to move backward by the syringe driving mechanism 117 can be operated only when the inclination detection sensor 122 determines the preparation posture.

  The completion detection unit 144 corresponds to a function of the CPU 131 executing predetermined data processing corresponding to the computer program and the detection data of the linear encoder 119, and the like, depending on the moving position and moving distance of the syringe drive mechanism 117, Detect the completion with exclusion individually.

  More specifically, in the chemical injection device 100 of the present embodiment, the shape of the chemical syringe 200 to be attached is defined, and therefore the positions of the front end and the rear end of the cylinder member 210 are known. Therefore, the chemical injection device 100 recognizes the position of the piston member 220 moved by the syringe drive mechanism 117 based on the detection data of the linear encoder 119, and detects the completion of the chemical liquid inhalation when the position moves from the front end to the end of the cylinder member 210. To do.

  In addition, in the liquid injector 100 of this embodiment, for example, the minimum moving distance of the piston member 220 necessary for removing bubbles is also registered, and the piston member 220 that the syringe drive mechanism 117 moves forward after the liquid suction is completed. Is recognized by the detection data of the linear encoder 119, and when the detected distance exceeds the registered distance, the completion of the bubble removal is detected.

  For this reason, in the state where the initial setting is completed, the above-described operation driving means 143 is in a state in which only the chemical solution suction for retracting the piston member 220 by the syringe driving mechanism 117 can be operated, and the bubble for retracting the piston member 220 by the syringe driving mechanism 117. Exclusion is disabled until completion of inhalation of the chemical is detected.

  The injection control means 145 corresponds to a function in which the CPU 131 controls the operation of the syringe drive mechanism 117 corresponding to the computer program and the detection data of the linear encoder 119 and the inclination detection sensor 122, and the completion of the chemical solution suction and the bubble removal is completed. When the injection posture is determined after the detection in order, the chemical solution injection means 141 is made operable.

  The drive restricting means 146 corresponds to a function of the CPU 131 controlling the operation of the syringe drive mechanism 117 in response to the computer program and the detection data of the attachment / detachment detection sensor 120. If the attachment of the chemical syringe 200 is not detected, the drive is driven. The mechanism 117 is forcibly stopped.

  The various means of the chemical injection device 100 as described above are realized by using hardware such as the main / sub touch panel 104 or 121 as necessary, but the main means are resources stored in the information storage medium such as the ROM 132 and the like. This is realized by the function of the CPU 131 as hardware corresponding to the computer program.

  Such a computer program causes the CPU 131 to control the operation of the syringe drive mechanism 117 in accordance with, for example, input operations to the main / sub touch panels 104 and 121, detection data of the attachment / detachment detection sensor 120 and the inclination detection sensor 122, and the like. As software for this purpose, it is stored in an information storage medium such as the ROM 132.

[Operation of the embodiment]
In the configuration as described above, when the chemical injection device 100 of this embodiment is used, as shown in FIG. 5, the chemical injection device 100 is disposed in the vicinity of the imaging unit 401 of the CT angio device 400, and a new empty A chemical syringe 200, a pressure-resistant cover 300, a chemical tank filled with the chemical, an intake tube, an injection tube (not shown), and the like are prepared.

  Next, as shown in FIGS. 3 and 4, the chemical syringe 200 is attached to the injection execution head 110 of the chemical injection device 100 together with the pressure-resistant cover 300, and the chemical solution tank is connected to the chemical syringe 200 through an intake tube. Note that the attachment / detachment of the chemical syringe 200 to / from the injection execution head 110 as described above and the attachment / detachment of the suction tube to the chemical syringe 200 are usually performed as shown in FIG. Is executed while the injection execution head 110 is in the injection posture.

  When the chemical syringe 200 is attached to the injection execution head 110 together with the pressure-resistant cover 300, in the chemical injection device 100 of this embodiment, the attachment / detachment detection sensor 120 detects the attachment of the chemical syringe 200 as shown in FIG. 7 (step S1). In response to this detection, initial setting is executed (step S2).

  In the chemical injection device 100 of this embodiment, in the initial state where the initial setting is completed as described above, the bubble elimination and the chemical injection are inoperable, and only the chemical inhalation can be operated. The main / sub touch panel indicates that the mounting of the chemical syringe 200 has been detected, the initial setting has been completed, the chemical liquid inhalation, the bubble elimination and the chemical liquid injection have not been completed, and the chemical liquid inhalation should be executed first. The operator is notified by the message display of 104, 121 or the like.

  Thus, for example, when an operator inputs a chemical solution inhalation to the sub-touch panel 104 of the injection execution head 110 after connecting the chemical solution tank to the chemical solution syringe 200 of the injection execution head 110 in the injection posture with an intake tube (step S3). In response to this input operation, chemical solution inhalation is executed (step S5).

  In this chemical solution inhalation, since the piston member 220 is pulled out from the inner tip of the cylinder member 210 by the syringe driving mechanism 117 at a predetermined speed and a predetermined pressure, the chemical solution is sucked from the chemical solution tank into the chemical solution syringe 200. During the execution of the chemical solution inhalation, it is always monitored that the chemical solution syringe 200 is attached (step S4), and if this is not detected, the occurrence of an error is determined. In this case, for example, the drive mechanism 117 is forcibly stopped, and the operator is notified of the occurrence of an error by displaying messages on the main / sub touch panels 104 and 121.

  In the chemical solution injection device 100 of the present embodiment, the above-described chemical solution suction is executed only when the operator manually operates the sub-touch panel 104 of the injection execution head 110 (steps S3 and S5). Inhalation of chemicals is not performed without confirmation. Since the position where the syringe drive mechanism 117 moves the piston member 220 is detected by the linear encoder 119 when the chemical solution is being sucked in this way, when the moving position reaches a predetermined position, the suction completion is completed. Detected and the chemical solution inhalation is stopped (step S6).

  When this chemical solution inhalation is completed, for example, the fact that the chemical solution inhalation has been completed and that the bubble removal should be executed with the injection execution head 110 as the preparation posture is output to the operator via the main / sub touch panel 104, 121 or the like. The Therefore, the operator removes the suction tube from the chemical solution syringe 200 of the injection execution head 110 in the injection posture, attaches the injection tube, sets the injection execution head 110 to the preparation posture, and then eliminates bubbles on the sub-touch panel 104 of the injection execution head 110. Is input (step S7), bubble elimination is executed in response to the input operation (step S10).

  In this bubble elimination, since the piston member 220 is press-fitted into the cylinder member 210 at a predetermined speed and a predetermined pressure by the syringe drive mechanism 117, the bubbles are excluded from the drug solution syringe 200 and the injection tube is filled with the drug solution. At this time, since the chemical syringe 200 is arranged in the preparation posture together with the injection execution head 110, the bubbles are well excluded from the chemical syringe 200 and the injection tube.

  During the execution of the bubble removal, it is constantly monitored that the injection execution head 110 is in the ready posture and the chemical syringe 200 is mounted (steps S8 and S9), and an error occurs if neither of them is detected. Occurrence is determined. In this case, for example, the drive mechanism 117 is forcibly stopped, and the occurrence of an error is notified by a message display on the main / sub touch panel 104, 121. When the liquid syringe 200 is rotated or when the chemical syringe 200 is dropped, the bubble removal is stopped and an error is notified to the operator.

  Since this bubble removal is also executed only when the operator manually operates the sub-touch panel 104 of the injection execution head 110 (steps S7, S10, S12), the bubble removal is executed without confirmation by the operator. There is nothing to do. Since the distance at which the syringe drive mechanism 117 press-fits the piston member 220 is detected by the linear encoder 119 when the chemical solution is being sucked in this way, the completion of removal is detected when the press-fit distance reaches a predetermined distance. (Step S11).

  In a state where this exclusion completion is not detected (step S11), a state where only bubble elimination is executed is maintained (steps S7 to S10), and when completion is detected (step S11), a preparation posture is detected. If so, the bubble removal is executed manually (steps S12 and S13). For this reason, the completion of the bubble elimination is confirmed twice by the apparatus and the operator, and the bubble elimination is not completed in a state where the bubbles are not completely eliminated from the chemical solution of the chemical solution syringe 200. .

  Then, after completion of the bubble removal is detected (step S11), when the bubble removal input operation is stopped (step S12), for example, the bubble removal is completed, and the liquid injection is performed with the injection execution head 110 as the injection posture. Is notified to the operator via the main / sub touch panel 104, 121 or the like. Therefore, the operator connects the injection tube filled with the chemical solution to the blood vessel of the subject, and rotates the injection execution head 110 from the preparation posture to the injection posture as shown in FIG.

  Then, since the injection posture of the injection execution head 110 is detected by the inclination detection sensor 122 (Step S13), only the chemical injection can be executed in response to this detection (Step S17). For example, the injection of the chemical is executed. The main / sub touch panel 104, 121 and the like are notified and output to the operator.

  Therefore, when this operator inputs the chemical liquid injection on the main touch panel 104 (step S14), for example, in response to the injection speed, injection pressure, injection volume, etc., which are input to the main touch panel 104 in advance by the operator, Since the piston member 220 is press-fitted into the cylinder member 210, the drug solution is injected from the drug solution syringe 200 to the subject (step S17).

  At this time, since the liquid syringe 200 is arranged in an injection posture together with the injection execution head 110, even if minute bubbles are present inside the liquid syringe 200, this is not injected into the subject. Even during the execution of this chemical solution injection, it is constantly monitored that the injection execution head 110 is in the injection posture and the chemical solution syringe 200 is mounted (steps S15 and S16), and if one of them is not detected, an error occurs. Determined.

  Also in this case, for example, the drive mechanism 117 is forcibly stopped, and the occurrence of an error is notified by displaying a message on the main / sub touch panel 104, 121. Therefore, the injection execution head 110 performs the injection when the chemical solution is being injected. When the medical solution syringe 200 is dropped from the posture or the chemical solution syringe 200 is dropped, the chemical solution injection is stopped and the operator is notified of the occurrence of an error.

  Note that the position where the syringe drive mechanism 117 moves the piston member 220 is detected by the linear encoder 119 even when the above-described chemical liquid injection is being performed, so that the injection completion is detected when the movement position reaches the set position. Then, the chemical liquid injection is finished (step S18).

  In the fluoroscopic imaging system 1000 of this embodiment, since the chemical solution injection device 100 and the CT angiography device 400 communicate with each other to link each operation, until the chemical solution injection device 100 starts the chemical solution injection as described above, The CT angiography apparatus 400 is automatically started when the imaging of the CT angiography apparatus 400 is not started and, for example, a predetermined time elapses after the chemical injection apparatus 100 starts the chemical injection.

[Effect of the embodiment]
In the fluoroscopic imaging system 1000 of this embodiment, as described above, in the initial state, only the chemical solution can be sucked into the chemical syringe 200, and when the chemical solution suction is completed and the injection execution head 110 is set in the ready posture, only the bubble removal is performed. When the injection execution head 110 is in the injection posture after the bubble removal is completed, only the chemical solution injection can be executed.

  For this reason, it is necessary to add a release switch or to perform operations to eliminate bubbles with the chemical syringe 200 that has not been inhaled, and to perform chemical injection with the chemical syringe 200 that has not completed the bubble exclusion. This can be automatically prevented without requiring an increase in burden. In particular, the chemical solution inhalation and the bubble elimination are executed corresponding to the manual operation in real time, but the completion is detected by the moving distance and the moving position of the syringe drive mechanism 117. Completion of bubble removal can be determined.

  In addition, it is monitored whether or not the injection execution head 110 is arranged in the preparation posture when the bubble elimination is executed, and it is also monitored whether or not the injection execution head 110 is arranged in the injection posture when the chemical solution injection is executed. Is done. When the posture change is detected, the above operation is forcibly stopped, so that it is possible to automatically prevent the bubble removal or the chemical solution injection from being performed in an inappropriate posture.

  Furthermore, the attachment / detachment of the chemical syringe 200 is also detected, and when the attachment of the chemical syringe 200 is detected, the bubble elimination and the chemical injection are initially set to be unexecutable, so this initial setting is accurately executed. Moreover, it is also monitored whether the chemical syringe 200 is attached when the chemical solution inhalation, bubble elimination, and chemical solution injection are being performed, and the operation is forcibly stopped when the attachment is not detected. It is possible to automatically prevent various operations from being continued in a state in which 200 is dropped.

  Moreover, since the sub-touch panel 121 for inputting the execution of the chemical solution inhalation and the bubble elimination to the chemical solution injection apparatus 100 is mounted on the injection execution head 110 to which the chemical solution syringe 200 is mounted, the execution of the chemical solution inhalation and the bubble elimination is input. The operating operator can surely confirm the state of the chemical solution inhalation and the bubble elimination.

  Furthermore, in the fluoroscopic imaging system 1000 of this embodiment, since the chemical injection of the chemical injection device 100 and the image imaging of the CT angiography device 400 are automatically linked, a fluoroscopic image can be obtained from the subject into which the contrast agent is injected at an accurate timing. An image can be taken.

[Modification of Embodiment]
The present invention is not limited to the above embodiment, and various modifications are allowed without departing from the scope of the present invention. For example, in the above embodiment, the chemical solution injection device 100 in which the chemical solution inhalation, the bubble elimination, and the chemical solution injection are sequentially executed by the refill type chemical solution syringe 200 is illustrated, but the bubble removal and the chemical solution injection are performed by the refill type or prefilled type chemical solution syringe. It is also possible to implement a chemical solution injection device in which only the steps are executed sequentially (not shown). In addition, in the chemical solution injection device in which only the bubble elimination and the chemical solution injection are executed with the refill type chemical solution syringe, for example, it is preferable to cause the chemical solution syringe to execute the chemical solution inhalation with a dedicated chemical solution suction device (not shown). .

Moreover, although the chemical | medical solution injection apparatus 100 which uses only the refill type chemical | medical solution syringe 200 was illustrated in the said form, the chemical | medical solution injection | pouring apparatus etc. which use a refill type and a prefilled type chemical | medical solution syringe together is also implementable (not shown). . When implementing such a chemical injection device, for example, RFID (Radio) in which refill / prefilled syringe types are registered as data is used.
(Frequency Identification) chip is attached to a chemical syringe, and an RFID reader that reads data from the RFID chip is mounted on the chemical injection device as syringe discrimination means (both not shown).

  Therefore, it is determined whether the liquid syringe attached to the injection execution head is a prefilled type or a refill type, and in the prefilled type liquid syringe, when the injection execution head is in the preparation posture from the initial state, only the bubble elimination can be executed, When the injection execution head is in the injection posture after the bubble elimination is completed, only the chemical solution injection can be executed.

  In the refill type liquid syringe, only the liquid solution inhalation can be executed in the initial state, and when the liquid injection is completed and the injection execution head is in the preparation posture, only the bubble removal can be performed, and the bubble removal is completed. When the injection execution head is in the injection posture, only the chemical solution injection can be executed.

  In such a chemical liquid injector, chemical liquid injection is executed with a prefilled type chemical liquid syringe in which bubble elimination has not been completed, and air bubble exclusion is executed with a refill type chemical syringe that has not been inhaled with chemical liquid. Then, it is possible to automatically prevent the chemical liquid injection from being executed by the refill type chemical liquid syringe in which the bubble elimination has not been completed without requiring an additional release switch or an increase in work load.

  In addition, as described above, the system in which the RFID chip is attached to the chemical syringe and the RFID reader is attached to the chemical injection device is disclosed in Japanese Patent Application No. 2004-059034, Japanese Patent Application No. 2004-207345, Applications are filed as Japanese Patent Application Nos. 2004-327479, 2004-334492, and 2004-345493.

  Further, in the above embodiment, for the sake of simplicity of explanation, it is exemplified that the chemical liquid inhalation is immediately performed on the refill type chemical liquid syringe 200 in the initial state, but the current general refill type chemical liquid syringe 200 is in the initial state. Then, since the piston member 220 is located in the vicinity of the end of the cylinder member 210, it is necessary to prepare for inhalation to move the piston member 220 to the vicinity of the tip of the cylinder member 210 prior to inhalation of the chemical solution.

  Therefore, in such a chemical injection device using the chemical syringe 200, only the preparation for inhalation can be activated in the initial state, and after the preparation for inhalation is completed, the chemical inhalation can be activated, and the chemical inhalation is completed. Therefore, it is preferable that the bubble removal can be activated according to the preparation posture. It should be noted that the completion of the preparation for inhalation in such a chemical liquid injector is also preferably detected based on the movement distance and movement position of the syringe drive mechanism 117.

  Further, in the above embodiment, for simplification of description, it has been described that the bubble removal by the chemical solution injection device 100 is simultaneously performed on the injection tube together with the chemical solution syringe 200. However, the bubble removal by the chemical solution injection device 100 is performed on the chemical solution syringe 200. However, it is possible to eliminate the bubbles in the injection tube by using a dedicated exhaust valve.

  Further, in the above embodiment, it is exemplified that the inclination detection sensor 122, which is a posture determination unit for determining whether the injection execution head 110 is in the preparation posture or the injection posture, includes an acceleration sensor. However, such a posture determination unit has various configurations. For example, it can be realized by a device that independently detects its own direction, such as a mercury switch, a direction sensor, a geomagnetic sensor, or a device that detects a relative angle with respect to the movable arm 112 such as a rotary encoder. (Not shown).

  Moreover, in the said form, although the chemical | medical solution injection device 100 which has one syringe drive mechanism 117 illustrated inject | pouring only a contrast agent, the chemical | medical solution which inject | pours a contrast agent and physiological saline with two syringe drive mechanisms 117 An injection device or a chemical solution injection device that injects three or more types of chemical solutions with three or more syringe drive mechanisms 117 can also be implemented (not shown).

  Furthermore, in the above embodiment, the CT angiography apparatus 400 is used as the fluoroscopic imaging apparatus, and the chemical injection apparatus 100 injects the CT contrast agent. However, for example, an MRI apparatus or a PET apparatus is used as the fluoroscopic imaging apparatus. However, it is also possible for the drug solution injection device to inject a contrast medium for that purpose.

  Moreover, in the said form, it was illustrated that various means are logically implement | achieved as various functions of the chemical | medical solution injection apparatus 100, when CPU131 operate | moves corresponding to the computer program stored in RAM133 grade | etc.,. However, each of these various means can be formed as unique hardware, and a part can be stored in the RAM 133 or the like as software, and a part can be formed as hardware.

Claims (10)

A chemical member is inserted from a chemical solution tank into a cylinder member having a conduit portion formed at the tip thereof, and a piston member is slidably inserted from an opening at the end thereof, thereby moving the chemical solution from the chemical solution tank to the chemical solution. A chemical liquid injection device for injecting into a subject after inhaling into a syringe,
(A) an injection execution head to which the chemical syringe is detachably attached;
(B) a syringe drive mechanism for relatively moving the cylinder member and the piston member of the chemical syringe mounted on the injection execution head;
(C) Chemical liquid injection means for press-fitting the piston member into the cylinder member by operation control of the syringe drive mechanism for injecting the chemical liquid from the chemical liquid syringe to the subject.
(D) initial setting means for initially setting the chemical injection means to be inoperable;
(E) a manual operating unit for accepting an input operation for running the chemical suction and to be taken at least the chemical into the liquid syringe from the liquid tank into the syringe driving mechanism,
(F) an operating drive means for the input operation to the manual operating unit paired with response actuating the syringe driving mechanism,
(G) completion detection means for detecting completion of the chemical solution inhalation by at least one of a movement distance and a movement position of the syringe drive mechanism;
Injection control means for enabling the chemical liquid injection means to be activated when completion of the chemical liquid inhalation is detected;
A chemical injection device. A chemical member is inserted from a chemical solution tank into a cylinder member having a conduit portion formed at the tip thereof, and a piston member is slidably inserted from an opening at the end thereof, thereby moving the chemical solution from the chemical solution tank to the chemical solution. A chemical liquid injection device for injecting into a subject after inhaling into a syringe,
(A) an injection execution head to which the chemical syringe is detachably attached;
(B) a syringe drive mechanism for relatively moving the cylinder member and the piston member of the chemical syringe mounted on the injection execution head;
(C) Chemical liquid injection means for press-fitting the piston member into the cylinder member by operation control of the syringe drive mechanism for injecting the chemical liquid from the chemical liquid syringe to the subject.
(D) initial setting means for initially setting the chemical injection means to be inoperable;
(E1) manual operation at least the chemical accepts an input operation for execution and a bubble elimination to eliminate air bubbles from the liquid chemical of the liquid syringe with a chemical solution suction and to be taken in the liquid syringe from the liquid tank to the syringe drive mechanism Means,
(F) an operating drive means for the input operation to the manual operating unit paired with response actuating the syringe driving mechanism,
(G1) completion detection means for individually detecting the completion of the chemical solution inhalation and the bubble elimination by at least one of a movement distance and a movement position of the syringe drive mechanism;
(H1) An injection control means for operating the chemical liquid injection means when completion of the chemical liquid inhalation and the bubble elimination is detected in sequence;
A chemical injection device. At least the drug solution is injected into the subject by relatively moving the cylinder member and the piston member of the drug solution syringe in which the piston member is slidably inserted from the opening at the end of the cylinder member having a conduit portion formed at the tip. A chemical injection device,
(A1) An injection execution head on which the prefilled type liquid chemical syringe filled with the liquid chemical from the beginning and the refill type liquid chemical syringe for sucking the liquid chemical from an external liquid chemical tank are selectively and detachably mounted. ,
(B1) a syringe drive mechanism that relatively moves the cylinder member and the piston member of the chemical syringe attached to the injection execution head;
(C) Chemical liquid injection means for press-fitting the piston member into the cylinder member by operation control of the syringe drive mechanism for injecting the chemical liquid from the chemical liquid syringe to the subject.
(D) initial setting means for initially setting the chemical injection means to be inoperable;
(E1) manual operation at least the chemical accepts an input operation for execution and a bubble elimination to eliminate air bubbles from the liquid chemical of the liquid syringe with a chemical solution suction and to be taken in the liquid syringe from the liquid tank to the syringe drive mechanism Means,
(F) an operating drive means for the input operation to the manual operating unit paired with response actuating the syringe driving mechanism,
(G1) completion detection means for individually detecting the completion of the chemical solution inhalation and the bubble elimination by at least one of a movement distance and a movement position of the syringe drive mechanism;
(I) Syringe discrimination means for discriminating whether the liquid syringe attached to the injection execution head is the prefilled type or the refill type;
(H2) When the prefilled type is determined, if the completion of the bubble elimination is detected, the chemical solution injecting means can be operated, and when the refill type is determined, the chemical solution inhalation and the bubble elimination are performed. Injection control means for enabling the medicinal solution injection means when the completion of the is detected in turn,
A chemical injection device. The operation driving means causes the syringe drive mechanism to execute only the bubble elimination corresponding to the input operation when the prefilled type is determined, and performs the input operation when the refill type is determined. Correspondingly, the chemical solution injection device according to claim 3 , wherein the syringe drive mechanism sequentially performs the chemical solution inhalation and the bubble elimination. The chemical syringe that performs the chemical liquid suction is, in the initial state, the piston member is disposed near the end of the cylinder member,
The manual operation means also accepts an input operation for inhalation preparation for moving the piston member of the chemical liquid syringe in which the chemical liquid inhalation is executed from the vicinity of the end of the cylinder member to the vicinity of the tip,
The completion detection means also detects completion of the inhalation preparation by at least one of a movement distance and a movement position of the syringe drive mechanism,
The chemical injection device according to any one of claims 1 to 4 , wherein the injection control means does not allow the chemical injection means to operate unless completion of the inhalation preparation and the chemical liquid inhalation is detected in order. A head support mechanism that supports the injection execution head movably in an injection posture in which the tip of the chemical syringe is positioned below the end and a preparation posture in the upper position;
Attitude determination means for determining whether the injection execution head is the injection attitude or the preparation attitude;
Also has
The chemical injection device according to any one of claims 2 to 4 , wherein the completion detection unit detects completion of the bubble removal only when the preparation posture is determined. A head support mechanism that supports the injection execution head movably in an injection posture in which the tip of the chemical syringe is positioned below the end and a preparation posture in the upper position;
Attitude determination means for determining whether the injection execution head is the injection attitude or the preparation attitude;
Also has
The chemical injection device according to any one of claims 1 to 6 , wherein the injection control means is in a state where the chemical injection means can be operated only when the injection posture is determined. It also has attachment / detachment detection means for detecting attachment of the chemical syringe to the injection execution head,
The said initial setting means is a chemical injection device as described in any one of Claims 1-7 which performs the said initial setting, when mounting | wearing of the said chemical | medical solution syringe is detected. Attachment / detachment detection means for detecting attachment of the chemical syringe;
Drive regulation means for disabling the syringe drive mechanism when the mounting of the chemical syringe is not detected, and
The said initial setting means is a chemical injection device as described in any one of Claims 1-7 which performs the said initial setting, when mounting | wearing of the said chemical | medical solution syringe is detected. The liquid medicine injection device according to any one of claims 1 to 9 , wherein the manual operation means is mounted on the injection execution head.

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