JPH07504152A - 生物活性ペプチドおよび標的細胞、ウイルス、あるいはウイルス感染細胞の成長を抑制する方法 - Google Patents

生物活性ペプチドおよび標的細胞、ウイルス、あるいはウイルス感染細胞の成長を抑制する方法

Info

Publication number: JPH07504152A
Authority: JP; Japan
Prior art keywords: peptide; administered; identification number; sequence; amino acid
Prior art date: 1990-02-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP3504910A

Other languages

English (en)

Japanese (ja)

Inventor

バーコウィッツ，バリー

マロイ，ダブリュー．，リー

カーリ，ユー．，プラサド

Original Assignee

マゲイニン　ファーマスーティカルズ，　インコーポレーテッド

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-08

Filing date

1991-02-04

Publication date

1995-05-11

1991-02-04 Application filed by マゲイニン　ファーマスーティカルズ，　インコーポレーテッド filed Critical マゲイニン　ファーマスーティカルズ，　インコーポレーテッド

1995-05-11 Publication of JPH07504152A publication Critical patent/JPH07504152A/ja

Status Pending legal-status Critical Current

Links

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LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 description 1
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229940049954 penicillin Drugs 0.000 description 1
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150000002978 peroxides Chemical class 0.000 description 1
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BPLBGHOLXOTWMN-MBNYWOFBSA-N phenoxymethylpenicillin Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)COC1=CC=CC=C1 BPLBGHOLXOTWMN-MBNYWOFBSA-N 0.000 description 1
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239000003910 polypeptide antibiotic agent Substances 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
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WSOSYBUSMXEYDO-UHFFFAOYSA-N propamidine isethionate Chemical compound OCCS(O)(=O)=O.OCCS(O)(=O)=O.C1=CC(C(=N)N)=CC=C1OCCCOC1=CC=C(C(N)=N)C=C1 WSOSYBUSMXEYDO-UHFFFAOYSA-N 0.000 description 1
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LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 description 1
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BTVYFIMKUHNOBZ-QXMMDKDBSA-N rifamycin s Chemical class O=C1C(C(O)=C2C)=C3C(=O)C=C1NC(=O)\C(C)=C/C=C\C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C(C)C(OC)\C=C/OC1(C)OC2=C3C1=O BTVYFIMKUHNOBZ-QXMMDKDBSA-N 0.000 description 1
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NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 description 1
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239000012138 yeast extract Substances 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Virology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

JP3504910A 1990-02-08 1991-02-04 生物活性ペプチドおよび標的細胞、ウイルス、あるいはウイルス感染細胞の成長を抑制する方法 Pending JPH07504152A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US47662990A	1990-02-08	1990-02-08
US476,629		1990-02-08
PCT/US1991/000725 WO1991012015A1 (fr)	1990-02-08	1991-02-04	Peptides amphiphiles biologiquement actifs et procede pour inhiber la croissance de cellules cibles, de virus ou de cellules contaminees par virus

Publications (1)

Publication Number	Publication Date
JPH07504152A true JPH07504152A (ja)	1995-05-11

Family

ID=23892624

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP3504910A Pending JPH07504152A (ja)	1990-02-08	1991-02-04	生物活性ペプチドおよび標的細胞、ウイルス、あるいはウイルス感染細胞の成長を抑制する方法

Country Status (4)

Country	Link
EP (1)	EP0514464A4 (fr)
JP (1)	JPH07504152A (fr)
CA (1)	CA2035959A1 (fr)
WO (1)	WO1991012015A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0533795A4 (en) *	1990-05-14	1993-10-20	Magainin Sciences, Inc.	Composition of and treatment with biologically active peptides having d-amino acid residues
JPH07502979A (ja) *	1991-07-25	1995-03-30	マゲイニン　ファーマス−ティカルズ，インコーポレーテッド	生物活性ペプチドを利用する口腔内の有害な状態の予防と治療
EP0644769A4 (fr) *	1992-06-01	1995-08-09	Magainin Pharma	Peptides biologiquement actifs presentant des substitutions n-terminales.
US5654274A (en) *	1992-06-01	1997-08-05	Magainin Pharmaceuticals, Inc.	Biologically active peptides having N-terminal substitutions
US6348445B1 (en)	1992-06-01	2002-02-19	Magainin Pharmaceuticals, Inc.	Biologically active peptides with reduced toxicity in animals and a method for preparing same
US5593866A (en) *	1992-08-21	1997-01-14	The University Of British Columbia	Cationic peptides and method for production
US5455253A (en) *	1992-10-20	1995-10-03	Zeneca Limited	Heterocyclic derivatives
US5424290A (en) *	1992-10-26	1995-06-13	Magainin Pharmaceuticals Inc.	Biologically active peptides and uses therefor
WO1995019370A1 (fr) *	1994-01-18	1995-07-20	Magainin Pharmaceuticals Inc.	Peptides amphiphiliques formant des canaux ioniques et presentant des modifications n-terminales
GB9504761D0 (en) *	1995-03-09	1995-04-26	Unilever Plc	Amphiphilic peptide and analogs thereof
US6057291A (en)	1995-06-02	2000-05-02	University Of British Columbia	Antimicrobial cationic peptides
AU6940796A (en) *	1995-08-23	1997-03-19	University Of British Columbia, The	Antimicrobial cationic peptides and methods of screening for the same
US8318899B2 (en)	2008-01-24	2012-11-27	Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College	Lytic domain fusion constructs and methods of making and using same
LT2379096T (lt) *	2008-12-19	2019-12-27	Baxalta GmbH	Tfpi inhibitoriai ir vartojimo būdai
EP4035685A1 (fr)	2012-10-30	2022-08-03	Esperance Pharmaceuticals, Inc.	Conjugués anticorps-médicament et procédés d'utilisation

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE436645C (sv) *	1976-04-29	1996-07-22	Bonnierfoeretagen Ab	Antigeniskt aktiv polypeptid, som kan användas vid cancerdiagnosticering och vid framställning av antikroppar
US4659692A (en) *	1982-11-19	1987-04-21	The Regents Of The University Of California	Cationic oligopeptides having microbicidal activity
DE3324534A1 (de) *	1983-07-07	1985-01-17	Ciba-Geigy Ag, Basel	Modifizierte protease-inhibitoren, verfahren zu ihrer herstellung und daraus bereitete pharmazeutische mittel
US4617149A (en) *	1983-09-21	1986-10-14	Eli Lilly And Company	Growth hormone release factor analogs
DE3438296A1 (de) *	1984-04-18	1985-11-07	Hoechst Ag, 6230 Frankfurt	Neue polypeptide mit blutgerinnungshemmender wirkung, verfahren zu deren herstellung bzw. gewinnung, deren verwendung und diese enthaltende mittel
DE3689525D1 (de) *	1985-07-17	1994-02-24	Hoechst Ag	Neue Polypeptide mit blutgerinnungshemmender Wirkung, Verfahren zu deren Herstellung bzw. Gewinnung, deren Verwendung und diese enthaltende Mittel.

1991
- 1991-02-04 WO PCT/US1991/000725 patent/WO1991012015A1/fr not_active Application Discontinuation
- 1991-02-04 EP EP19910904427 patent/EP0514464A4/en not_active Withdrawn
- 1991-02-04 JP JP3504910A patent/JPH07504152A/ja active Pending
- 1991-02-07 CA CA002035959A patent/CA2035959A1/fr not_active Abandoned

Also Published As

Publication number	Publication date
EP0514464A1 (fr)	1992-11-25
CA2035959A1 (fr)	1991-08-09
EP0514464A4 (en)	1993-04-28
WO1991012015A1 (fr)	1991-08-22

Publication	Publication Date	Title
US5470950A (en)	1995-11-28	Biologically active amphiphilic peptide compositions and uses therefor
JPH08505854A (ja)	1996-06-25	修飾された末端を有するアミノ酸及びペプチド
AU657781B2 (en)	1995-03-23	Novel biologically active peptide compositions and uses therefor
JPH07504152A (ja)	1995-05-11	生物活性ペプチドおよび標的細胞、ウイルス、あるいはウイルス感染細胞の成長を抑制する方法
US5424290A (en)	1995-06-13	Biologically active peptides and uses therefor
US5792831A (en)	1998-08-11	Analogues of magainin peptides containing D-amino acids
AU652261B2 (en)	1994-08-18	Novel biologically active peptide compositions and uses therefor
AU654714B2 (en)	1994-11-17	Novel peptide compositions and uses therefor
JPH06511234A (ja)	1994-12-15	Ｃ末端置換を有する生物活性ペプチド組成物および治療法
US5654274A (en)	1997-08-05	Biologically active peptides having N-terminal substitutions
US5459237A (en)	1995-10-17	Peptide compositions and uses therefor
US5208220A (en)	1993-05-04	Composition and treatment with biologically active peptides and antibiotics which inhibit DNA gyrase
JPH07501820A (ja)	1995-02-23	生物活性ペプチドおよびキレート剤による組成物および治療法
AU693518B2 (en)	1998-07-02	Ion-channel forming amphiphilic peptides having n-terminal modifications
JPH05507273A (ja)	1993-10-21	Ｄアミノ酸残基を有する生物活性ペプチドの組成物およびそれによる治療方法
JPH07500342A (ja)	1995-01-12	生物学的活性ペプチドおよび抗生物質を有する組成物およびこれを用いた治療
JP2001510164A (ja)	2001-07-31	動物に対する毒性を減じた生物活性ペプチドおよび同ペプチドを調製する方法。
JPH06509062A (ja)	1994-10-13	新規なペプチド組成物およびその用途
EP0559647A4 (fr)	1993-07-15	COMPOSITION ET TRAITEMENT A L'AIDE DE PEPTIDES BIOLOGIQUEMENT ACTIFS ET D'ANTIBIOTIQUES INHIBANT LA GYRASE d'ADN.