JPH08157386A - Athlete's foot treating agent - Google Patents

Abstract

PURPOSE: To obtain a nontoxic and safe athlete's foot treating agent capable of providing high sterilizing effect on trichophyton. CONSTITUTION: This athlete's foot contains vinegar, garlic and extract of Houttuynia cordata as main ingredients and contains at least one selected from hen's egg, squeezed juice of citrus fruits and cow milk as other ingredient.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a therapeutic agent for athlete's foot.

[0002]

BACKGROUND OF THE INVENTION Athlete's foot is caused by infection with a filamentous fungus called Trichophyton, and conventionally, anti-trichophyton agents such as tincture of iodine and vaseline salicylate have been used for its treatment.

[0003]

By the way, as a therapeutic agent for athlete's foot of this kind, a highly safe agent which is effective and has no side effects or irritation is desired. Therefore, plants such as those containing an extract of mandarin orange described in JP-A-49-20319 as a main component and those containing an extract of aloe described in JP-A-57-134420 as a main component It has been proposed that the main component of the extract is to reduce side effects and irritation. Therefore, the present inventor
Plants that contain ingredients that are effective in sterilizing Trichophyton (medicinal herbs, wild plants, etc.)
The present invention has been completed by paying attention to the bactericidal action of vinegar and the action of penetrating human stratum corneum. That is, in view of the above-mentioned circumstances, the present invention also aims to provide a therapeutic agent for athlete's foot that contains a plant extract as a main component, is harmless, is safe, and has a high bactericidal effect on Trichophyton.

[0004]

For this reason, the therapeutic agent for athlete's foot of the present invention is characterized by containing vinegar, garlic, and extract of Dodami edible grass as main components. As other components, at least one selected from chicken eggs, citrus juice and milk can be included.

[0005]

[Action] The athlete's foot remedy of the present invention has the effect that vinegar penetrates into the stratum corneum of humans, and the garlic and the ingredient effective in sterilizing Trichophyton in the extract of Dokudami grass penetrate into the affected area. It is presumed that it will work. Further, since a large amount of mucilage is contained in garlic, it is possible to suppress the volatilization of the drug after application and maintain the action on the affected area.

By the way, the metabolism of normal human skin is
New cells are constantly created in the basal layer of the epidermis and migrate to the surface while maturing. And it becomes anucleated cell keratin,
The so-called turnover activity, which is a natural activity of the skin that eventually peels off into horn pieces, is carried out. This drug reacted only with the part affected by Trichophyton without inhibiting the normal skin turnover activity, and was observed to promote exfoliation of corneous horn fragments only in the diseased part.

The main component of garlic is alliin,
Upon grinding, allicin is generated by the activity of oxygen allinase. It is well known that this allicin has sufficient antibacterial activity even when diluted to a considerably low concentration. The main component of the extract of Dokudami grass is decanoylacetaldehyde. It has been found that this decanoylacetaldehyde also has a strong antibacterial action against staphylococci and filamentous fungi. It is also presumed that chlorophyll (chlorophyll) contained in Dokudomi-kusa helps recovery of the granulation tissue of the skin, which has been lost due to exfoliation of the horny horny piece of the affected area.

[0008]

EXAMPLES The present invention will be specifically described below with reference to examples. Mix 300 ml of vinegar (with 20% acidity) with the following ingredients and pulverize with a mixer to obtain a mixed solution 1 in the dark.
After storing for about a week, filter to remove fibrous material,
A remedy for athlete's foot was obtained. 50 g raw garlic 50 g raw dodami grass 50 g citrus fruits (yuzu / lemon) 50 g

Next, a method of using the remedy for athlete's foot and a result of use will be shown. This agent is used by diluting it with distilled water to an acidity of about 5% to 18% in consideration of the feeling of irritation to the affected area, but it may be diluted with milk instead of distilled water.

Six subjects were mild (2 dry and 1 wet each) and 2 moderate (dry
3 for wetness (1 person each) and 2 severe persons (1 each for dry and wetness)
The product was divided into two groups, and the product was diluted to 18% acidity and applied to the affected area twice a day in the morning and evening, and a clinical trial was conducted. The observation results of the healing state are shown below. (1). From the 4th day after the start of use, three people with dry disease were gradually able to confirm the exfoliation phenomenon of the stratum corneum on the skin surface. After that, the peeling phenomenon of the exfoliated pieces was repeated in all three persons, and the normal skin was regenerated for about 4 weeks for the mild person and after 45 days for the moderate and severe persons. (2). When a person with mild wetness was observed after 1 week, the stratum corneum of the affected area was white and swollen and thickened, and after 17 days, the thickened part was about to peel off, so after bathing, that part When peeled, it peeled off without difficulty. After that, the thin skin on the skin surface was repeatedly peeled off, and normal skin was regenerated after 33 days had passed. (3). A person with moderate wetness had a tear in the crotch of the fingers and complained of irritation pain. So, after switching from the second time to one with an acidity of 9%, after 1 week, the affected area was observed. , The part that had been torn was closed and the skin was regenerated, and the part that had not been torn was white and thickened and thickened. After that, since the irritation pain disappeared, the acid level was switched to 18% again. Then 3
Normal skin regenerated after 7 days. (4) .In severe cases, the affected area was in an erosive state at the beginning of application of this drug, but one week later, when the affected area was observed,
The erosive part fell off and was covered with thin skin, and the skin was reddish. Thereafter, the thin skin on the skin surface was repeatedly peeled off, and normal skin was regenerated after 42 days had passed.

As described above, this product may be left as it is after being applied to the affected area of athlete's foot, but if it is prevented from volatilizing from the affected area after application of this product, the effect of penetration of this product into the stratum corneum and It has been found that the bactericidal effect lasts and a favorable effect is obtained. Therefore, socks made of highly airtight rubber,
After making gloves, finger cots, and bandage-like envelopes, using them together and wearing cut cotton coated with this drug on the affected area,
A more preferable healing effect can be obtained by sealing or sealing with these encapsulants. In addition, this drug
It was also found that since it is composed of a liquid having a high acid property, it is possible to obtain a favorable effect by applying it to skin diseases (especially heat rash) in summer. Furthermore, 2 chicken eggs (excluding the shell portion) were mixed and contained in the product obtained in this example with a mixer, and the solution was dipped in cut cotton and applied to spots formed on the skin, and the outside was airtight. It was also confirmed that the spots disappeared when the product was sealed or sealed with a highly adhesive bandage.

No side effects such as abnormalities of the skin after the treatment are observed.

[0013]

As described above, the therapeutic agent for athlete's foot of the present invention comprises:
Since it contains a plant extract as a main component, it has an excellent effect that it is harmless, safe, and has a high bactericidal effect of Trichophyton.

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Claims (2)

[Claims] 1. A remedy for athlete's foot, which comprises vinegar, garlic, and extract of Dodami Doshimi as the main components. 2. A remedy for athlete's foot, which comprises at least one selected from chicken eggs, citrus juice and milk as other components.