JPS5711970A - Quinazolinone compound and its preparation - Google Patents
Quinazolinone compound and its preparationInfo
- Publication number
- JPS5711970A JPS5711970A JP8604480A JP8604480A JPS5711970A JP S5711970 A JPS5711970 A JP S5711970A JP 8604480 A JP8604480 A JP 8604480A JP 8604480 A JP8604480 A JP 8604480A JP S5711970 A JPS5711970 A JP S5711970A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- ring
- compound expressed
- phenyl
- expressed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The titled compound expressed by formula I (ring A is benzene ring which may have a substituent group selected from F, Cl, Br, OCH3 and CH3 at the 5-, 6- or 7-position of the quinazoline ring; ring B is phenyl which may have one or two substituent groups selected from F, Cl, Br and CH3 at the 2-, 3- and 4-positions) or a salt thereof.
EXAMPLE: 1-Isopropyl-2-phenyl-4(1H)-quinazolinone.
USE: A medicine having improved anti-inflammatory, analgesic and antiallergic actions.
PROCESS: A benzamide derivative expressed by formula II is condensed with a benzoyl halide compound expressed by formula III (X is Cl or Br) in a suitable solvent at room temperature or under heating at 100°C or below, and the resultant 2-(N-benzoyl-N-isopropylamino)benzamide compound is dehydrated and cyclized through the condensing and cyclizing reaction to give the compound expressed by formula I.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8604480A JPS5711970A (en) | 1980-06-24 | 1980-06-24 | Quinazolinone compound and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8604480A JPS5711970A (en) | 1980-06-24 | 1980-06-24 | Quinazolinone compound and its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5711970A true JPS5711970A (en) | 1982-01-21 |
Family
ID=13875670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8604480A Pending JPS5711970A (en) | 1980-06-24 | 1980-06-24 | Quinazolinone compound and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5711970A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008086730A1 (en) * | 2007-01-16 | 2008-07-24 | Beijing Molecule Science And Technology Co. , Ltd | Tetrahydroquinazoline compounds and their use in preparing medicaments for treating and preventing virosis |
| CN100432059C (en) * | 2002-10-11 | 2008-11-12 | 诺瓦提斯公司 | Quinazolinone derivatives useful as anti-hyperalgesic agents |
-
1980
- 1980-06-24 JP JP8604480A patent/JPS5711970A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100432059C (en) * | 2002-10-11 | 2008-11-12 | 诺瓦提斯公司 | Quinazolinone derivatives useful as anti-hyperalgesic agents |
| WO2008086730A1 (en) * | 2007-01-16 | 2008-07-24 | Beijing Molecule Science And Technology Co. , Ltd | Tetrahydroquinazoline compounds and their use in preparing medicaments for treating and preventing virosis |
| JP2010515763A (en) * | 2007-01-16 | 2010-05-13 | ベイジン・モレキュール・サイエンス・アンド・テクノロジー・カンパニー・リミテッド | Tetrahydroquinazoline compounds and their use in preparing drugs for treating and preventing viral diseases |
| US8188091B2 (en) | 2007-01-16 | 2012-05-29 | Beijing Molecule Science And Technology Co., Ltd. | Tetrahydroquinazoline compounds and their use in preparing medicaments for treating and preventing virosis |
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