KR100553078B1 - 2-layer hydrophilic polyurethane foam dressing material - Google Patents

Abstract

The present invention relates to a hydrophilic polyurethane foam dressing material effective for wound healing. The hydrophilic poly of the two-layered structure of the present invention comprises a sponge-like absorbent layer 10 having a water absorption of 400 to 2,000% by weight, and a film-like protective layer 20 having a water vapor transmission rate of 200 to 1500 g / m 2 · day. Provided urethane foam dressing material. In addition, the sponge structure of the absorber layer 10 is composed of an open cell 12 having an average diameter of 50 to 400 µm, and the cells 12 and 12 have pores 15 having an average diameter of 10 to 80 µm. It is penetrated by, and the density is characterized by having a range of 0.20 to 0.40 g / cm 3. The present invention provides a dressing material capable of efficient wound repair by maintaining an appropriate wet environment for the wound from its structural features and at the same time preventing the dressing material from adhering to the wound surface.

Wound, Wet Environment, Polyurethane Foam Dressing Material, Absorption Layer, Protective Layer

Description

Hydrophilic polyurethane foam dressing with double-layer structure

1 is a schematic cross-sectional view of the polyurethane foam dressing material of the present invention.

Figure 2 is a scanning electron micrograph of the cross section of the absorbent layer of the polyurethane foam dressing material prepared according to the present invention.

Figure 3 is a scanning electron micrograph of the cross-section of the absorption layer according to the prior art.

Figure 4 is a scanning electron micrograph of the cross-section of the absorption layer according to the prior art.

<Description of Symbols for Main Parts of Drawings>

10: absorber layer 12: open cell

15: pore 20: protective layer

FIELD OF THE INVENTION The present invention relates to wound dressings for use in the protection of wounds and, in particular, to occlusive dressings that provide a moist environment. More specifically, a polyurethane foam dressing material having a two-layer structure consisting of an absorbent layer and a protective layer, wherein the absorbent layer has a sponge-like structure of an open cell having an average diameter of 50 to 400 μm, The average diameter of the pores penetrating the cell is 10-80 μm, the density is in the range of 0.20-0.40 g / cm 3, and the absorbance is 400-2,000% by weight. The film-like protective layer has a moisture permeability of 200 to 1500 g / m 2 · day and has a function of waterproofing of moisture. The polyurethane foam dressing material of the two-layer structure according to the present invention is simply manufactured as a structure in which the absorbent layer and the protective layer are laminated and provide excellent wound healing effects.

When a wound is formed on the skin, it passes through the inflammatory phase during which a large amount of exudate is generated, and then goes through a proliferative phase in which granulation occurs in earnest, and a maturation phase that strengthens the new skin. The most important thing in the treatment of the wound is the absorption and wetting of the early inflammatory exudates. It is non-adhesive property of wound surface of environmental maintenance and dressing material.

Ordinary gauze dressings are easy to absorb wound secretions, but they do not have the ability to protect against infections such as bacteria from the outside and keep the wound dry so that treatment is delayed. But there are problems such as accompanied by damage to the new tissue and pain. In addition, since the exudates are generated in the early stages of healing, there is also the need to change the dressing material several times a day. Currently, various closed dressing materials have been developed and used to improve the problems of gauze dressing materials, but due to their high price and lack of controllability of absorbency and moisture permeability, they are not widely applied to various wounds and are mainly applied to specific wounds.

Types of currently closed dressing materials that are mainly used include film type, hydrocolloid type, hydrogel type, polyurethane foam type and the like. In particular, the dressing material having a high therapeutic effect may include a hydrocolloid type, a hydrogel type, and a polyurethane foam type.

The hydrocolloid type shown in U.S. Patent Nos. 5,503,847 and 5,830,932 is composed of a pressure-sensitive adhesive composition layer, a hydrocolloid layer that mitigates the impact from the outside world and absorbs the exudates, and a film layer that prevents the penetration of bacteria and foreign substances. The hydrocolloid-type dressing material absorbs a small amount of wound secretion to form a gel, provides a wet environment, and maintains pH at a weak acidity for a long time, thereby providing an environment for preventing tissue damage and promoting cell growth. However, it lacks the moisture permeability and the ability to absorb exudates, and because the gel remains on the wound surface when it is replaced or removed, it needs a second removal operation and it is not suitable to be applied to wounds with a large amount of discharge. There is this.

The hydrogel types shown in US Pat. Nos. 5,501,661 and 5,489,262 form a form in which hydrogel is applied to a polymer film layer having no permeability, the polymer film layer prevents the hydrogel from being dehydrated or dried, and the hydrogel layer is wound. It absorbs the exudates from the cotton and promotes wound healing by maintaining a moist environment. However, due to low moisture permeability and absorbency, it is impossible to use a wound with a large amount of exudates, and when excessive absorption occurs, the dressing material is deformed and causes inflammation of the normal skin.

The hydrophilic polyurethane foam dressing material disclosed in US Pat. Nos. 5,445,604 and 5,065,752 has a structure in which the film is laminated on both sides of the polyurethane foam, and the film contacting the wound surface is mechanically drilled with fine holes to exudate the effluent well. To be absorbed. However, if it is applied to a wound that has a large amount of exudate, the exudation capacity per unit area is insufficient, so frequent exchange is necessary.If the exudate is not generated, the exudation of the exudate from the area without the pores is generated. There is such a problem that it is not smooth, there is a problem such that the regeneration tissue is attached due to the large holes present in the film on the wound side.

Accordingly, the present invention provides a polyurethane foam dressing material, which is a closed dressing material which can improve the low water absorption, low moisture permeability, wound surface adhesion, low physical properties and manufacturing complexity and expect an effective wound healing effect of the conventional dressing material. The purpose is.

In order to achieve the above object, the present invention is a hydrophilic dressing material, characterized in that the two-layer structure in which the water-absorbing layer 400 to 2,000% by weight of the water-absorbing layer of the film-like protective layer of 200 to 1500g / ㎡ · day is laminated It provides a polyurethane foam dressing material. Further, it consists of an open cell (penetrated by pores having an average diameter of 10 to 80 µm) having an average diameter of 50 to 400 µm having a sponge structure of the absorbing layer, and has a density of 0.20 to 0.40 g / It is characterized by a range of cm 3.

MEANS TO SOLVE THE PROBLEM After earnestly researching, in the structure of a polyurethane foam dressing material, it has a 2-layer structure of a film-form protective layer and a sponge-like absorbing layer. The protective layer has a moisture-permeable waterproofing property with a moisture permeability of 200-1,500 g / m 2 · day, and the absorbing layer has a water absorption of 400-2,000 wt%, a density of 0.20-0.40 g / cm 3 and an average diameter of 10-80 μm. It has a high density sponge-like structure composed of open cells having an average diameter of 50 to 400 μm penetrated by pores. In addition, the high-density sponge-like absorbent layer was prepared by molding a high-density block foam (Block Foam) and then slicing to a predetermined thickness. In the present invention, the sponge-like absorbent layer and the film-like protective layer prepared by lamination were prepared, and the efficient closing dressing completely solved the above-mentioned problems of low absorption and wound surface adhesion from the simple manufacturing method and the structural features of the absorbent layer. Provide ash.

Hereinafter, with reference to the accompanying drawings will be described in detail the present invention.

1 is a schematic cross-sectional view of a polyurethane foam dressing material of the present invention. Polyurethane foam dressing material according to the present invention is a two-layer structure consisting of the absorbent layer 10 and the protective layer 20, the protective layer 20 is a film of 10 ~ 300㎛ thickness of 200 ~ 1,500g / ㎡ · day moisture permeability Has The protective layer 20 has a non-porous structure that is free of pores so that bacteria or foreign substances from the outside cannot enter. Non-porous means that when observed by scanning electron microscope or transmission electron microscope, pores cannot be observed at their resolution and no pores of 20 nm or more are not present in an unswelled state. It means that it does not include the independent bubbles and pin holes generated inside the film in the manufacturing process. The protective layer 20 is a film of a variety of materials are used, but a polyurethane film is preferred, in the production of a polyurethane film is dissolved in a solvent, coated on a release paper, etc., dried and prepared as a solvent, dimethylformamide (DMF), methyl ethyl ketone (MEK) and the like are used. In general, various polyurethanes may be used, and an adhesive polyurethane film having an adhesive applied to the film may also be used. In addition, a natural rubber or other synthetic polymer film can be used, and even when such a film is used, a soft thin film having a moisture permeability of 200 to 1,500 g / m 2 · day is used.

The absorber layer 10 has an open cell 12 having an average diameter of 50 to 400 μm, and an average diameter of 10 to 80 penetrating between the cell 12 and the cell 12 formed on the wall of the open cell 12. It has a pore 15 of 탆, and has a sponge-like structure in which the ratio of the open cells 12 accounts for 60% or more. It has a high density with a density of 0.20 to 0.40 g / cm 3 and a high water absorption of 400 to 2,000% by weight.

2 is a scanning electron microscope (SEM) picture of the absorbing layer 10 manufactured according to an embodiment of the present invention, which is clearly distinguished from the scanning electron microscope picture of another product. That is, Fig. 3 is an Allevyn product of S Company having an average diameter of 600 μm and a pore of 300 μm, and Fig. 4 is an average diameter of the cell. It is a polymem product manufactured by F Company having a diameter of 700 µm and an average diameter of pores of 300 µm. As compared to FIGS. 2 to 4, the absorbing layer 10 according to the present invention has a high density sponge structure having microcells and pores.

The sponge-like absorbent layer 10 is a polyurethane prepolymer obtained by reacting at least one polyol with an isocyanate compound in an amount of 15 to 45% by weight of a blowing agent, 5 to 35% by weight of a crosslinking agent, and a surfactant, a humectant, and a pigment. 0.5-15 weight% of additives containing these etc. are added, and it manufactures from the mixture which mixed and stirred. In this case, the additive may further include a wound healing accelerator, a release agent, an antimicrobial agent, a cell growth factor, and the like. The mixed and stirred mixture is injected into a mold release container and manufactured by free foaming at room temperature, or preferably by foaming into a mold of a constant shape. At this time, the temperature of the mold is 20 ~ 60 ℃ and 5 to 60 minutes after the injection and demoulding. The foamed polyurethane foam is cut into the desired shape and size to suit the application and applied to the absorbent layer 10. The foam molding in the mold has a simple process and can be cut and used in various shapes and thicknesses, thereby providing excellent manufacturing convenience and various shapes.

In the production of the polyurethane prepolymer, the polyether polyols are preferably synthesized in a ratio of 0.15 to 0.95 moles per 1 to 3 moles of isocyanate.

Isocyanates include isophorone diisocyanate, 2,4-toluene diisocyanate and its isomers, diphenylmethane diisocyanate, hexamethylene diisocyanate, lysine diisocyanate, trimethylhexamethylene diisocyanate, bis (2-isocyanate ether) -fumarate , 3,3'-dimethyl-4,4'-diphenylmethane diisocyanate, 1,6-hexanediisocyanate, 4,4'-biphenylene diisocyanate, 3,3'-dimethylphenylene diisocyanate, p-phenyl Rendiisocyanate, m-phenylenediisocyanate, 1,5-naphthalene diisocyanate, 1,4-xylene diisocyanate, 1,3-xylene diisocyanate and the like can be used, preferably diphenylmethane diisocyanate, 2,4 Toluene diisocyanate and isomers thereof, p-phenylenedi isocyanate, isophorone diisocyanate, hexamethylene diisocyane It is better to use an agent.

The polyether polyols have an ethylene oxide / propylene oxide random copolymer having three or more hydroxyl groups in a molecule having a molecular weight of 3,000 to 6,000 and an ethylene oxide content of 50 to 80%, and two or more hydroxyl groups in a molecule and having a molecular weight of 1,000 to A ethylene oxide / propylene oxide random copolymer having a molecular weight of 3,000 to 6,000 and an ethylene oxide content of 50 to 80% having three hydroxyl groups in a molecule, and may be mixed at 30:70 to a weight of 4,000 polypropylene glycol. It is better to use alone. However, other isocyanate compounds and polyols not mentioned above may be mixed for controlling physical properties.

The blowing agent may be used chlorofluorocarbon (CFC-141b), methylene chloride (Methylenecholride) and distilled water, preferably distilled water.

 The crosslinking agent has 1,3-butanediol, 1,4-butanediol, 1,5-pentanediol, 1,6-hexanediol, neopentylglycol, propylene glycol, ethylene glycol, and molecular weight of 200 to 2 or more hydroxyl groups in the molecule. 2,000 polyethylene glycol, glycerol, trimethylol ethane, trimethylol propane, pentaerythritol, sorbose, sorbitol (sorbitiol) and the like can be used alone or in combination, preferably glycerol, sorbitol And polyethylene glycol and trimethylolpropane having a molecular weight of 200 to 2,000 are preferred.

As an additive, the surfactant is ethylene oxide propylene oxide block copolymer L-62, L-64, P-84, P-85, P-105, F-68, F-87, F-88, F from BASF, Germany. -108, F-127 or a mixture thereof and one or two or more selected from O-Si's L-508, L-5305, L-5302, L-3150, etc., which are silicone-based surfactants, can be mixed and used as a moisturizing agent. As for polyacrylic acid, polyvinyl alcohol, polyoxyethylene, polyethylene oxide, polysaccharide, polymethacrylic acid, polyacrylamide, polyethylene oxide and cellulose, carboxymethylcellulose, pectin, guar gum, sodium alginate, chitin, chitosan, One or a mixture of two or more selected from super absorbent polymers and natural products consisting of gelatin, starch, hydroxyethyl cellulose, xanthan gum, pulp, karaya gum and the like can be used.

The lamination of the film-like protective layer 20 and the sponge-like absorbent layer 10 may be performed by a simple process of heat or pressurization, or may be performed by simultaneously performing heat and pressurization as necessary. In addition, the adhesive layer may be laminated on one surface of the protective layer 20 or the absorption layer 10 in a state where the adhesive is applied.

Hereinafter, specific synthesis examples, examples, and comparative examples of the present invention will be described.

[Film Production Example]

18-25 g of polyurethane elastomer was mixed in a mixed solvent of dimethylformamide (DMF) and methyl ethyl ketone (MEK) (DMF: MEK = 30: 70) and melted while heating and stirring at 60 ℃ to form a viscous liquid. The urethane solution was obtained. Then, both sides of the release paper treated with silicon were fixed with a gauge bar having a predetermined thickness, the polyurethane solution was poured onto the release treated paper, and the film was coated with a film coater in a uniform thickness, and then in a 100 ° C. oven. It dried over 1 hour. At this time, by varying the coating thickness, several polyurethane films having a thickness of 20, 50, 100, 200 μm after drying were obtained.

[Synthesis example of absorbing layer polyurethane prepolymer]

Polyurethane prepolymers having isocyanate end groups were prepared using a 3 liter round bottom flask equipped with a stirrer, and 354 g of diphenylmethane diisocyanate and 314 g of isophorone diisocyanate were heated and heated to 60 ° C., followed by two or more hydroxyl groups. And a small amount of ethylene oxide / propylene oxide random copolymer was added and reacted for 7 hours until the theoretical NCO% 12 was reached. At this time, a sample was taken in the middle of the reaction to measure NCO%, and NCO% was determined by titrimetry using n-butylamine standard solution.

Example 1

57.1 wt% of the polyurethane prepolymer prepared in the above synthesis example, 26.7 wt% of distilled water as a blowing agent, 14 wt% of glycerin as a crosslinking agent, 1.0 wt% of F-127 (BASF) as an additive, 0.4 wt% of L-64, as a moisturizing agent 5.7% by weight of carboxymethyl cellulose was added and stirred at 4,000 rpm for 5 seconds, and then injected into a mold of a predetermined shape to prepare a foam. At this time, the temperature of the mold was 25 ℃ and opened and closed demolding 10 minutes after the injection. And after removing the skin layer using a horizontal cutting machine was cut to a thickness of 5mm, a foam dressing material was completed by attaching a 20㎛ thick polyurethane film obtained in the film manufacturing example on one side of the cut polyurethane foam. The density of the hydrophilic polyurethane foam dressing material according to the present example was 0.20 g / cm 3.

The hydrophilic polyurethane foam dressing material obtained as described above measured physical properties by the following method and the results are shown in Table 1 below.

(1) density

Taking a hydrophilic polyurethane foam dressing material in a constant size and measuring the weight (W) divided by the unit volume (V), it was calculated using the following equation.

                     Density (g / cm 3) = W / V

(2) Absorbance (%)

Take the hydrophilic polyurethane foam dressing material in the size of 3cm × 3cm and measure the initial weight (A), impregnate and store it in 25 ℃ distilled water for 24 hours, remove it, wipe the water on the surface with dust-free tissue, and then measure the weight (B). And it calculated using the following formula.

                   Absorbance (%) = (B-A) / A × 100

(3) retention

The weight (C) after placing the weight of 6kg weight for 20 seconds on the foam dressing material (3cm x 3cm) of the absorbance measurement was measured, and calculated using the following equation.

                   Retention (%) = (C-A) / A × 100

(4) moisture permeability

It was measured according to the test method of KS M 6886 using a thermo-hygrostat. At this time, the temperature was 37.5 ℃ and the relative humidity was 90% and the moisture permeability was calculated according to the following equation.

                   P = A / S

A = ((a ₁ -a ₀ ) + (a ₂ -a ₁ ) + (a ₃ -a ₂ )) / 3

                   Where P: water vapor permeability (g / ㎡ / 24hr)

                            A: average amount of increase per hour (g)

                            S: moisture permeation area of the test piece (㎡)

a ₀ : Weight measured after 1 hour

a ₁ , a ₂ , a ₃ : Weight measured after 2 hours, 3 hours and 4 hours

(5) cell and pore size measurement

The effluent absorption capacity varies depending on the size of the cells and pores of the foam as well as the hydrophilicity of the foam itself. That is, capillary suction per specific surface area varies depending on the size of the cell and the pore, which affects the effluent absorption capacity. Mercury Intrusion porosimetry may be used as a method for measuring cell and pore size, but a scanning electron microscope (SEM) is more commonly used. In the present invention, the size of the cells and pores of the hydrophilic polyurethane foam dressing material was measured using a scanning electron microscope.

Example 2

In the same manner as in Example 1, except that the surfactant composition was changed to 1.0% by weight of F-127 (BASF) and the composition of the moisturizer was changed to 1.6% by weight of carboxymethylcellulose to prepare a polyurethane foam. And the same film as Example 1 was stuck to one surface of the polyurethane foam, and it was completed. The density of the obtained foam dressing material was 0.26 g / cm <3>. Physical properties were measured by the method exemplified in Example 1 and the experimental results are shown in Table 1 below.

Example 3

66.7% by weight of the polyurethane prepolymer prepared in Synthesis Example compared to Example 1, 20.8% by weight of distilled water as a blowing agent, 10.9% by weight of glycerin as a crosslinking agent, 0.8% by weight of F-127 (BASF) as a surfactant, L- 64 0.3% by weight, carboxymethylcellulose 1.6% by weight as a moisturizing agent was injected into a mold of a predetermined shape to prepare a foam. At this time, the temperature of the mold was 25 ℃ and opened and closed demolding 10 minutes after the injection. And after removing the skin layer using a horizontal cutting machine was cut to 5mm thickness, the foam dressing material was completed by attaching a 20㎛ thick polyurethane film on one side of the cut polyurethane foam. The density of the obtained foam dressing material was 0.27 g / cm <3>. Physical properties were measured by the method exemplified in Example 1 and the experimental results are shown in Table 1 below.

Example 4

In the same manner as in Example 3, but was changed to 1.0% by weight of carboxymethyl cellulose with a moisturizing agent than Example 3 was injected into a mold of a predetermined shape to prepare a foam. Physical properties were measured by the method illustrated in Example 1. The experimental results are shown in Table 1 below.

Example 5

In the same manner as in Example 3, but the excess of the raw material was added to the mold than Example 3 to increase the density of the polyurethane foam dressing material to 0.31g / ㎠. Physical properties were measured by the method exemplified in Example 1 and the experimental results are shown in Table 1 below.

Example 6

In the same manner as in Example 3, but the excess of the raw material was added to the mold than Example 3 to increase the density of the polyurethane foam dressing material to 0.33g / cm 3. Physical properties were measured by the method illustrated in Example 1. The experimental results are shown in Table 1 below.

Example 7

In the same manner as in Example 3, except that excess raw material was added to the mold than Example 3 to prepare a density of the polyurethane foam dressing material 0.35g / cm3. Physical properties were measured by the method exemplified in Example 1 and the experimental results are shown in Table 1 below.

Example 8

The same method as in Example 7, except that the thickness of the polyurethane film was 50㎛. Physical properties were measured by the method illustrated in Example 1. The experimental results are shown in Table 1 below.

Example 9

The same method as in Example 7 was carried out, except that the polyurethane film had a thickness of 100 μm. Physical properties were measured by the method exemplified in Example 1, and the experimental results are shown in Table 1 below.

Example 10

The same method as in Example 7, except that the thickness of the polyurethane film was 200㎛. Physical properties were measured by the method exemplified in Example 1, and the experimental results are shown in Table 1 below.

Comparative Example 1

As a comparative example, a commercially available dressing product (Allevyn) in the form of a polyurethane foam of S company was applied. Physical properties were measured by the method exemplified in Example 1 and the experimental results are shown in Table 1 below.

Comparative Example 2

As a comparative example, a commercially available dressing product (Polymem) in the form of polyurethane foam of F company was applied. Physical properties were measured by the method exemplified in Example 1 and the experimental results are shown in Table 1 below.

  <Measurement results of the manufactured hydrophilic polyurethane foam dressing material> division Outer protective layer thickness (㎛) Density (g / cm 3) Average open cell size (μm) Average Pore Size (μm) Water vapor permeability (g / ㎡ / 24hr) Absorption test Absorbance (%) Retention degree (%) Example 1 20 0.20 300 70 800 1,500 560 Example 2 20 0.26 250 65 800 1,300 720 Example 3 20 0.27 200 60 800 1,200 750 Example 4 20 0.27 200 44 800 1,200 650 Example 5 20 0.31 195 40 800 1,200 450 Example 6 20 0.33 190 35 800 1,200 560 Example 7 20 0.35 180 40 800 1,100 640 Example 8 50 0.35 180 40 650 1,100 640 Example 9 100 0.35 180 40 400 1,100 640 Example 10 200 0.35 180 40 250 1,100 640 Comparative Example 1 - 0.14 600 300 1,400 600 300 Comparative Example 2 - 0.21 700 300 600 770 250

As can be seen in Table 1, when the density of the polyurethane foam dressing material is decreased, the size of the open cell 12 may be increased and the number and size of the pores 15 may be increased. In addition, it can be seen that the adjustment of the amount of absorption is easy by the amount of the moisturizer added during the production of polyurethane foam. That is, in Examples 5, 6, and 7 was added to the excess raw material during the production of polyurethane foam density change, as a result it can be seen that the swelling degree can be adjusted according to the density. That is, as the density increases, the size of the open cell 12 and the pore 15 decreases. In addition, as can be seen in Examples 3 and 4, it can be seen that as the amount of the moisturizer increases in the manufacture of the polyurethane foam, the hydrophilicity increases to increase the retention.

Accordingly, as shown in Table 1, the foam dressing material (example) according to the present invention is a two-layered structure having a film and has excellent moisture permeability, and has a suitable size of the cells 12 and pores 15 as compared. Compared with Examples 1 and 2 it can be seen that it has an excellent absorption and retention.

The foam dressing material according to the present invention maintains an appropriate wetting environment to the wound while preventing the invasion of bacteria or foreign substances by the protective layer 20 on the film having an appropriate moisture permeability and waterproof properties. Moreover, it consists of the open cell 12 of 50-400 micrometers of average diameters, and the pore 15 of 10-80 micrometers of average diameter which penetrates between this cell 12 and the cell 12, and 0.20-0.40 g / In cm 3, the absorbent layer 10 having a high-density sponge structure exhibits excellent absorbency, retention and wound surface non-adhesiveness. Accordingly, the foam dressing material of the present invention blocks foreign matters from the outside by the structural features as described above, and maintains an appropriate wet state by releasing the absorbed effluent to the outside in the form of water vapor or by storing it in a foam to make the wound surface wet. It has the effect of promoting wound healing while maintaining. The absorbent layer 10 in contact with the wound surface is easily exchanged due to its non-adhesive property from its structural characteristics, and a moisturizer selected from a super absorbent polymer is added to exhibit an excellent effluent absorption ability. .

In addition, the two-layer foam dressing material according to the present invention is laminated with a high-density sponge absorbent layer 10 prepared by slicing a block foam foamed from a mold onto a protective layer 20 on a film. It has a simple manufacturing process.

Claims (5)

A hydrophilic dressing material comprising an open cell 12 having an average diameter of 50 to 400 μm and a pore 15 having an average diameter of 10 to 80 μm that penetrates the cell 12 and the cell 12. In the absorbent layer 10 of the sponge structure that absorbs and stores 2,000% by weight, Polyurethane foam dressing material characterized by the two-layer structure in which the film-like protective layer 20 of moisture permeability of 200-1,500 g / m <2> * day is laminated. The polyurethane foam dressing material as claimed in claim 1, wherein the absorbent layer has a density in the range of 0.20 to 0.40 g / cm 3. The absorbing layer 10 is 40 to 70% by weight of polyurethane prepolymer, 15 to 45% by weight of blowing agent, 5 to 35% by weight of crosslinking agent, and 0.5 to 0.15% by weight of an additive including a surfactant, a humectant, and a pigment. Polyurethane foam dressing material, characterized in that prepared by mixing and stirring the injection foam in the mold to produce a polyurethane foam and then slicing it. The polyurethane foam dressing material according to claim 1, wherein the protective layer (20) is a moisture-permeable waterproof film having a thickness of 10 to 300 µm and is laminated after a lamination or an adhesive is directly applied to the absorbent layer (10) of the sponge structure. The moisturizing agent of claim 3, wherein the moisturizing agent is polyacrylic acid, polyvinyl alcohol, polyoxyethylene, polyethylene oxide, polysaccharide, polymethacrylic acid, polyacrylamide, polyethylene oxide and cellulose, carboxymethyl cellulose, pectin, guar gum, sodium Polyurethane foam characterized in that one or more mixtures selected from superabsorbent polymers and natural product groups consisting of alginate, chitin, chitosan, gelatin, starch, hydroxyethylcellulose, xanthan gum, pulp and karaya gum are used. Dressing material.

Images