KR101663053B1 - Composition for hair surface modification - Google Patents

Abstract

The present invention relates to a composition for modifying a surface of hair. According to the present invention, a composition for modifying a surface of hair contains a particular carbodiimide-based compound, and forms a covalent bond without damaging hair, thereby providing a desired effect of semi-permanently modifying a surface of the hair. The carbodiimide-based compound is represented by chemical formula 2.

Description

[Composition for hair surface modification]

The present invention relates to a hair surface modifying composition.

In general, a person's haircuticle consists of flatly superimposed cells (scales). Cuticle cells are attached from the root to the tip of the hair as if they were roof tiles. Each cuticle layer has a thickness of about 0.3 to 0.5 mu m, and a portion of the cuticle shown is about 5 to 10 mu m. Cuticles of human hair are generally stacked five to ten layers. Each cuticle cell in the hair is composed of various sublamella layers such as an epicuticle, an A-layer, an exocuticle, an endocuticle, and an inner layer, and a cell membrane (Cell membrane complex). The outermost epicuticle layer is covered with covalently bound lipid (fatty acid), and the most abundant component is 18-Methyl Eicosanoic Acid (18-MEA). This layer constitutes the outer β-layer of the cuticle cell membrane complex and acts like lubrication, friction reduction, and hydrophobic surface formation.

In the hair, the portion that goes out from the scalp is called the morning sock, which varies with the lifespan and length of the hair. Also, when cutting hair, using shampoo, hair dryer, brushing, perming, hair coloring, etc., it is affected by environmental stresses such as drying, ultraviolet rays, seawater and limestone in the pool. In particular, the morpheme surrounding the outer part of the moraine is damaged if it is accumulated in a complex manner even if it is not directly affected by such stress. Damaged hair is peeled off or partially peeled off from the tip of the mosquito. These hairs lose their gloss and become non-smooth due to diffuse reflection of light. More damage to the hair leads to the complete removal of the layer of mosquito, which exposes the inner follicle and eventually breaks or breaks the hair.

Various treatments have been attempted to improve the surface of hair damaged by 18-MEA. In particular, a product that provides a hair surface modifying effect, that is, a hair strengthening effect, such as hair manicure or hair essence, Have been sold or are being applied through hairdressing rooms. Especially, there have been many products such as shampoos for strengthening the hair through coating of the hair surface or penetration of amino acids into the hair.

However, in the case of using the hair-modifying ingredient as the hair-modifying ingredient, it only provides a temporary and short-term effect until the next washing after the treatment, but there is always the inconvenience of reprocessing after cleaning. Therefore, although various methods for increasing the conditioning effect of the hair cosmetic and personal care products have been continuously studied, most of them are one-time even if the conditioning effect is excellent.

Patent Document 1 discloses a cosmetic treatment method for keeping cosmetic properties on hair for a long time. In the above technique, a process of activating the hair primarily through physical methods such as heat, electromagnetic wave, electric field, sound wave, and plasma, or chemical method except for the reduction method, which causes a change in the surface of the hair before the hair make- . However, such hair activating process must apply high energy such as heat, electromagnetic wave, electric field, sound wave, and plasma to hair, and oxidizing agents such as hydrogen peroxide and bromate, which are used as chemical inactivating substances except reduction method, cause serious damage to hair, Other polyamines or polysaccharide polymers can be activated, but these polymers are not active in covalent form on the hair and are easily removed by washing.

Patent Document 2 discloses a non-aqueous personal care product for skin or hair, which comprises a non-water-based functional group capable of forming a covalent bond with a hair or a protein moiety on the surface of a skin, such as carbonate, aldehyde, propionaldehyde ), Butylaldehyde, nitrophenyl carbonate, aziridine, isocyanate, thiocyanate, epoxide, tresylate, succinimide, succinimide, hydroxysuccinimidyl ester, imidazole, oxycarbonylamidazole, imine, thiol, vinylsulfone, ethyleneimine, , Thioether, acrylonitrile, acrylic acid or methacrylic ester, disulfi (disulfide) (wherein R is any one selected from the group consisting of alkyl, aryl, aralkyl, cyclic and unsaturated rings and X is I, Br or Cl) selected from the group consisting of de, ketone and RX. Discloses a personal care product for hair or skin characterized in that it is separated into a non-aqueous part and a water-based part containing a hair surface modifying component having at least any one of them and is mixed immediately before use. However, (1.9-3.1%) and skin keratin (3.1 ~ 6.9%) in the amino acids of the proteins constituting the skin of the hair, 18%) and skin keratin (2.3 ~ 3.8%) are targeted and reacted, so that the reaction efficiency is lowered and each substance must be synthesized separately There is a problem.

Japanese Laid-Open Patent Application No. 2004-182731 Korean Patent Publication No. 2008-0064467

It is an object of the present invention to provide a hair surface modifying composition capable of continuously imparting a semi-permanent surface modifying effect without damaging the hair.

As a means for solving the above problems, the present invention provides a carbodiimide compound represented by the following formula (1): And a hair-modifying component.

[Chemical Formula 1]

In the above formula (1), A represents a monomer having at least one of the structures listed below and having isocyanate (*) groups at both ends of the repeating unit, wherein two A's are homopolymers having the same structure or different (Hetero Polymer), R is hydrogen; Or a linear or branched chain or cyclic hydrocarbon having 1 to 500 carbon atoms; Or a benzene ring-type hydrocarbon, and the hydrocarbon molecule includes a double bond in a part of the molecule; At least one compound selected from the group consisting of O, N, S, P, and Si is substituted; Anion, cation, amphoteric form; Or a structure in which metal ions are bonded in the form of a salt, and m is an integer of 1 to 100.

As another means for solving the above problems, the present invention provides a hair care product comprising the hair surface modifying composition.

The hair surface modifying composition according to the present invention contains a specific hair surface modifying component and / or a specific carbodiimide compound into which a specific functional group capable of covalent bonding with a protein residue of hair is introduced, thereby forming a covalent bond without damaging the hair Thereby providing a semi-permanent surface modification effect.

The present invention relates to a hair surface modifying composition comprising a carbodiimide compound and a hair surface modifying component.

The hair surface modifying composition according to the present invention can be prepared, for example, by reacting a carbodiimide compound with a known hair surface modifying component to form a covalent bond with the hair protein through a reactive hair surface modifying component to which a carbodiimide group is bonded It is possible to maximize the effect of modifying the hair surface.

The carbodiimide compound is collectively referred to as a compound having a structure represented by the following formula (1) in its molecule:

[Chemical Formula 1]

M represents an integer of 1 to 100, A represents one or more monomers selected from the structures listed below and has isocyanate (*) groups at both terminals of the repeating unit, wherein two A have the same structure Homopolymer or heteropolymer of different structure, R is hydrogen; A straight chain, branched chain or cyclic hydrocarbon having 1 to 500 carbon atoms; Or a benzene ring-type hydrocarbon, and the hydrocarbon molecule includes a double bond in a part of the molecule; At least one compound selected from the group consisting of O, N, S, P, and Si is substituted; Anion, cation, amphoteric form; Or a structure in which metal ions are bonded in a salt form, but the present invention is not limited thereto. The cyclic hydrocarbon may include a structure including at least one compound selected from the group consisting of O, N and Si in the ring and / or a structure including a double bond.

An example of the carbodiimide polymer preferred in the present invention may be a carbodiimide compound represented by the following formula (2) wherein the terminal of the polymer is blocked with polyethylene glycol or polypropylene glycol.

(2)

In formula (2), A represents one or more monomers selected from the structures listed below and has isocyanate (*) groups at both ends of the repeating unit, wherein two A's are homopolymers having the same structure or different structures M is an integer of 1 to 100, and n is an integer of 1 to 1000. The term " Heteropolymer "

Further, an example of the carbodiimide-based polymer that is more preferable in the present invention may be a carbodiimide-based compound represented by the following general formula (3).

(3)

In the formula (3), n is an integer of 1 to 120 (preferably an integer of 1 to less than 100, more preferably an integer of 1 to less than 70), and m is an integer of 1 to less than 100 An integer of less than 30, more preferably an integer of 1 to less than 10).

An example of the most preferable carbodiimide polymer in the present invention is a polymer comprising 1, 1'-methylene-bis- (4-isocyanate) in which m is 1 to 7 and n is 5 to 50, (3-isocyanatocyclohexane), homopolymer, polyethylene glycol, mono-Me-ether-blocked) have.

When the number of carbodiimide groups present in one molecule is more than 100, the viscosity of the starting material is too large, the molecular weight is excessively large, the reaction position in which the reaction can be performed becomes excessively large, The molecule having the bodymide group becomes too large, and the efficiency is lowered by blocking the portion showing the functional effect of the molecule having the substantial function.

Specific examples of the carbodiimide compound in the present invention include 1,1'-methylene-bis- (4-isocyanatocyclohexane) -, homopolymer, polyethylene glycol mono-Me-ether- Methylene-bis- (4-isocyanatocyclohexane) -, homopolymer, polyethylene glycol mono-Me-ether-blocked, 1,1'- , Polyethylene glycol mono-Me-ether-blocked (1,1'-methylene-bis- (3-isocyanatocyclohexane) -, homopolymer, polyethylene glycol mono-Me- (4-isocyanatocycloheptane) -, homopolymer, polyethylene glycol mono-Me-ether-block (4-isocyanatocycloheptane), homopolymer, polyethylene glycol mono-Me- ether-blocked, 1,1'-methylene-bis- (3-isocyanatocycloheptane) -, homopolymer, polyethylene glycol mono-Mee- isocyanatocy (3-isocyanatocyclopentane) -, a homopolymer, a polyethylene glycol mono-Me-ether-block, a polyethylene glycol mono-Me- (3-isocyanatocyclopentane), homopolymer, and polyethylene glycol mono-Me-ether-blocked), but the present invention is not limited thereto.

The carbodiimide compound may be used in an amount of 0.0001 to 10 parts by weight, 0.001 to 7 parts by weight, or 0.01 to 5 parts by weight based on 100 parts by weight of the entire cosmetic composition. When the content is less than 0.0001 part by weight, there is a problem that the surface modification effect is not continuously exhibited. When the content exceeds 10 parts by weight, the carbodiimide compound, which exists excessively at the reaction position existing in the hair, There is a problem in that it can act as a component to be lost without reacting with the substance to improve persistence.

In the present invention, the term 'hair surface modification' refers to changing the properties of the surface of hair by applying to the hair to change the properties of the surface of the hair by coating the hair or bonding effective materials to make the hair look thicker, It can be used to improve damaged hair, prevent cracking, prevent breakage, strengthen tensile strength, increase thickness, increase hair, nutrition, increase elasticity, increase gloss, moisturize, prevent damage, repair damage, dye, decolorize, It imparts beneficial qualities such as removal, salting, anti-static, reduced porosity, volume, curl reduction, curl enhancement, film and film formation, softness, calmness or smoothness, Or to change the appearance of the hair or to impart moisture to the hair or to block the ultraviolet rays, It may be applied to hair, dispersed, etc. in a similar way to keep it strong. Hair surface modifying effect can exhibit effects such as antioxidation, conditioning, moisturizing, ultraviolet shielding, fragrance, dye, powder, bio junction, prevention and improvement of antibacterial and dandruff, wool, hair growth, hair growth, etc. However, It does not.

In the present invention, the term "hair surface modifying component" refers to a component that modifies an antioxidant component, conditioning (tensile strength, increase in thickness, elasticity, gloss, moisturization, prevention of damage, restoration of damage, prevention of cracking, Moisturizing, UV-blocking, anti-aging, anti-static, anti-static, anti-static, anti-static, Flavor components, dyes, bio-bonding components, antibacterial components, wool, hair growth or hair growth components, and the like.

The antioxidant component has an ability to significantly reduce or prevent the phenomenon that the oxidized skin function and structure are destroyed and exhausted, such as extracts derived from natural materials such as copper, plants and minerals, fermentation extracts, amino acids, peptides and proteins But are not limited to, antioxidant components. For example, acetamidocaproic acid, acetyl benzoyloxy prasterone, acetyl cysteine, 2-acetylhydroquinone, adamantanyl carbosamidohydride, But are not limited to, adamantanylcarboxamido hydroxylbenzamide, aminoethanesulfinic acid, aminopropyl ascorbyl phosphate, angoroside C, anserine, apigenin, arbutin but are not limited to, arbutin, alpha-albutin, ascorbic acid, asiaticoside, benzoquanamine, BHA (butylhydroxyanisol), BHT (butylated hydroxytoluene) Bis-hydroxyethyl tocopherylsuccinoylamido hydroxypropane, bis-tetramethylhydroxypyridinyl sebacate (b butylated xylenol, t-butylbenzamido hydroxylbenzamide, 4-butylresorcinol, caffeine, and the like. But are not limited to, caffeic acid, calcium ascorbate, carnosic acid, carotenoids, chitosan ascorbate, chlorogenic acid, cobalt DNA, , Copper adenosine triphosphate (ATP), copper pyridoxal 5-phosphate, curcumin, cysteine, cysteine HCl, decapeptide-6, Decapeptide-7, decursinol, decyl mercaptomethylimidazole, diamylhydroquinone, di-t-butyl hydroquinone, di-t- butylhydroquinone), dicetylthio But are not limited to, dicetyl thiodipropionate, dicyclopentadiene / t-butylcresol copolymer, digalloyl trioleate, diisooctyl sebacate, But are not limited to, dilauryl thiodipropionate, dimethoxybenzamido phenylhydroxylacetamide, dimethoxy di-p-cresol, dimethylmethoxy chromanol dimethylmethoxy chromanol, dimyristyl thiodipropionate, dioleyl tocopheryl methylsilanol, diosmine, diretinyl ether, dihoshodium ascorbyl sulfate disodium ascorbyl sulfate, distearyl thiodipropionate, ditridecyl thiodipropionate, dodecyl thiodipropionate, Dodecyl gallate, dunaliella bardawil powder, ellagic acid, epigallocatechin gallate, ergothioneine, protoplasmic bipartite protoplasts eriobotrya japonica leaf protoplasts, erythorbic acid, ethylbisiminomethylguaiacol manganese chloride, ethyl ferulate, ethylhexyl ferulate, ferulic acid, feruloyl soy glycerides, furfuryl palmitate, genistein glucoside, ginkgo leaf terpenoids, glucosylrutin, , Glyceryl chromonyl ether, glyceryl diferulate, hesperetin, hexyloxy trimethyl phenol ( hexyloxy trimethylphenol, honokiol, hydrolyzed proanthocyanidin, hydroquinone, p-hydroxyanisole, hydroxydecyl ubiquinone, Hydroxyamine hydrochloride, hydroxylamine sulfate, hydroxyphenyl dihydroxybenzamide, inositol hexaniacinate hexaascorbate, and the like. But are not limited to, isooctyl caprylate / caprate, isooctyl thioglycolate, isoquercitrin, kaempferol, kojic acid, kojyl glucoside, Kojyl methylenedioxycinnamate, black tea extract (kou-cha ekisu), lycopene, (Eg, magnesium, magnesium ascorbate, magnolol, manganese adenosine triphosphate (ATP), matrine, melatonin, methoxy PEG-7 aspartic acid PEG-7 ascorbic acid, methoxytrimethylphenyl dihydroxyphenyl propanol, methyl-di-t-butylhydroxyhydrocinnamate, methylenedithi-t-butyl Methyl methacrylate / trimethoxysilylpropyl methacrylate crosspolymer, methyl myristic acid, niacinamide hyde (methyl methacrylate / trimethoxysilylpropyl methacrylate crosspolymer), methylene di-t-butylcresol, methyl methacrylate / trimethoxysilylpropyl methacrylate crosspolymer, Niacinamide hydroxybenzoate, nictoflorin, nordihydroguaiaretic acid, octanicotinoyl epigallocate, < RTI ID = 0.0 > Octaicotinoyl epigallocatechin gallate, octapeptide-4, oligopeptide-28, paeonol, palmatine, PEG / PPG-2/5 tocopheryl- (PEG / PPG-2/5 tocopheryl ether), perillyl alcohol, phenethyl caffeate, phenylethyl resorcinol, phenylthioglycolic acid, Phlorotin, phloroglucinol, piceatannol, piperlonguminine, porphyridium polysaccharide, potassium ascorbyl tocopheryl phosphate, and the like. , Potassium sulfite, PPG-2 tocophereth-5, propyl gallate, protocatechuicaldehyde, puerarin, pyridoxine, Pyridoxine hydr oxybenzoate, phridyloxide t-butylnitrone, quercetin, resacetophenone, resorcinol, resveratrol, retinyl formylasparate, Rutin succinate, ryoku-cha ekisu, salnacedin, sodium ascorbate, sodium ascorbate, and the like. Sodium sulfite, sodium tocopheryl phosphate, sodium erythorbate, sodium phosphono-pyridoxylidenerhodanine, sodium thioglycolate sodium thioglycolate, sodium zinc histidine dithiooctanamide, sorbityl furfural, stearyl gallate, succinoyl ascorbate pentaerythritol, But are not limited to, succinoyl ascorbate pentapeptide-6, tangeritin, tert-butylhydroquinone (TBHQ), tetrabutyl ethylidine bisphenol, tetrahydrodemethoxydiferuloylmethane, But are not limited to, tetrahydrocurcumin diacetate, tetrahydrodiferuloylmethane, tetramethylbutyl dihydroxybenzamide, tetramethylchromanol glucoside, thioctic acid, Thiodiglycol, thiolactic acid, thiosalicylic acid, thioaurine, thymol trimethoxycinnamate, tococysteamide, tocopherol, Tocophereth-5, tocopherol, tocophersolan, tocopheryl acetone, Tocopheryl acetate, tocoquinone, toluene, o-tolyl biguanide, totarol, triprophylene glycol, Tris-BHT mesitylene ( tris-BHT mesitylene, tris (nonylphenyl) phosphate, trisodium ascorbyl isopalmitate phosphate, tyrosyl histidine HCl, ubiquinone ubiquinol, ubiquinone, ulva lactuca powder, uuron-cha ekisu, xylyl dibutylbenzofuranone, zinc adenosine triphosphate (ZTP), zinc Zinc dibutyldithiocarbamate, zinc fructose diphosphate, zinc pyridoxal 5-phosphate, and derivatives thereof. The term " zinc dibutyldithiocarbamate, zinc fructose diphosphate, zinc pyridoxal 5-phosphate, It is at least, but not limited to this.

The conditioning component may include, but is not limited to, natural ingredients extracts such as copper, plants, and minerals, amino acids, peptides, proteins, and the like, which can fill skin or hair damaged areas. For example, there may be mentioned natural extracts, amino acids, peptides, proteins, polymers, silicones, fatty alcohols, fatty acids, waxes, esters, fatty amidoamines, hydrocarbons, alkyl glyceryl esters, polyhydric alcohols, But are not limited to, active agents, powders and dyes, polyethylene, polypropylene, ceramides, vitamins, alkylamines, alkylamidoamines and derivatives thereof.

The extracts from natural products include seaweed extracts, sunflower seed extracts, ginseng extracts, ginseng extracts, chrysanthemum extracts, marigold extracts, birch sap, birch extract, flower extract, chrysanthemum extract, bergamot extract, Extracts, Chrysanthemum extract, Chrysanthemum extract, Chrysanthemum extract, Ginseng extract, Fennel extract, Lily of the valley, Cassis extract, Pomegranate extract, Lemon extract, Solanum extract, Green tea extract, Broccoli extract, Honeycomb extract, Honey extract, Propolis, Royal jelly, Cranberry The proteins and peptides may include proteins and peptides obtained from silk, silk, polylysine, seaweed, wool and hair, wheat, etc., and the like. But is not limited thereto.

Examples of the amino acid include glycine, alanine, valine, leucine, isoleucine, threonine, serine, cysteine, cystine, methionine, aspartic acid, asparagine, glutamic acid, diiodothyrosine, lysine, arginine, histidine, phenylalanine, tyrosine, tryptophan, Proline, and the like.

The polymer may be a linear polymer network compound having a molecular weight of 1,000 to 1,000,000 or a branched polymer network compound and may have a double bond or a ring structure if they contain a variety of substituents it may also be used, within the molecule terminal to any one -COONa to facilitate the reaction for attaching a reactive functional group in _{vivo, -COOK, -COOH, -NH 2,} -NHR, -NR 2, -Cl , -Br, -I, or -F group, it is preferable to include at least one reactive moiety in the molecule. More preferably a carbon number of about 10,000 to 500,000 chain and branched chain-like polymer, yet -COONa, to facilitate the reaction for attaching a reactive functional group in the living body within any one molecule the terminal -COOK, -COOH, -NH _2, -NHR a , -NR _2, -Cl, -Br, -I, or -F group may be used as the compound having at least one reactive moiety in the molecule. For example, a polyamine polymer, a polycarboxylic acid polymer, a polymer such as methacryloylethyl betaine / methacrylate copolymer, octyl acrylamide / acrylate / butylaminoethyl methacrylate copolymer Amphoteric polymers such as octylacrylamide / acrylates / butylaminoethyl methacrylate copolymer or polyvinylpyrrolidone, PVP / VA copolymer, PVP / dimethylaminoethyl methacrylate copolymer (PVP / Dimethylaminoethylmethacrylate Copolymer), and nonionic polymers such as acrylate methacrylate copolymer, Vie / crotonate / vinyl neodecanoate copolymer (VA / Crotonates / Vinyl Neodecanoate Copolymer) Anionic polymers, and the like, but are not limited thereto.

Examples of the silicone oils include dimethicone, trimethicone, phenylamodimethicone, amodimethicone, amodimiphenyltrimethicone, amodi-pentaphenyltrimethicone, dimethylpolysiloxane, methylphenylpolysiloxane, deca But are not limited to, compounds of the form of methylcyclopentasiloxane, methyltrimethicone, phenyltrimethicone, mechicone, cyclomethicone, alkylmethylsiloxane, dimethicone polyol, trimethylsilylamodimethicone.

The fatty alcohols are preferably chain and branched fatty alcohol compounds having about 10 to 50 carbon atoms such as lauryl alcohol, cetyl alcohol, stearyl alcohol, isostearyl alcohol and behenyl alcohol. It is not limited.

The fatty acids are chain and branched fatty acid compounds having about 10 to 50 carbon atoms, and examples thereof include 18-methylecycanoic acid, lauric acid, stearic acid, isostearic acid, and the like, but are not limited thereto.

The waxes may be, for example, but not limited to, candelilla wax, carnauba wax, rice wax, beeswax, lanolin, ozokerite, ceresin wax, paraffin wax, microcrystalline wax, polyethylene wax .

The ester oil may be selected from, for example, isopropyl myristate, butyl myristate, isopropyl palmitate, ethyl stearate isopropyl rinolate, decyl myristate, cetyl myristate, cetyl palmitate, hydrogenated polyisobutene Hydrogenated polyisobutaine, and the like.

The fatty amidoamines include, for example, stearylamidopropylamine, isostearylpropylamidoamine, stearylamidoamine, isostearylpropylamidoamine, methylecycloaminoamidopropylamine, Butanoylamidoamine, beanoamidopropylamine, behenylamidoamine, and the like, but are not limited thereto.

The saccharide is a monosaccharide and is a monosaccharide such as glycoaldehyde, glyceraldehyde, dihydroacetone, eridroside, erythrulose, ribose, arabinose, xylose, ribulose, xylose, glucose, fructose, There is provided a method for producing an oligosaccharide which comprises reacting galactose, mannose and disaccharides sucrose, maltose, lactose, trehalose, melibiose, cellobiose and polysaccharides raffinose, meleletose, maltotriose stearate, oligosaccharide, galactooligosaccharide, But are not limited to, fructooligosaccharide, jalanin, araban, starch, starch, dextrin, glycogen, cellulose, proctane, galactan, mannan and complex polysaccharides such as agar, algin, carrageenan, chitin, hemicellulose, Do not.

The ceramide is a substance having a structure in which a fatty acid is bound to the amino group of sphingosine, and includes natural and synthetic ceramides. The sphingosine, sphinganine, spinjenin, 2-amino- But are not limited to, sideromyelin, cerabroside, ganglioside, sphingolipids, derivatives thereof, and the like.

The moisturizing component may include, but is not limited to, extracts derived from natural products such as copper, plants and minerals, amino acids, peptides, proteins, saccharides, vitamins and the like. Examples of the solvent include glycerin, propylene glycol, butylene glycol, dipropylene glycol, caprylyl glycol, diglycerol, methylglucose, ethoxydiglycol, glycerol, propanediol, diethoxydigly But are not limited to, sorbitol, sorbitol, sorbitol, sorbitol, sorbitol, sorbitol, sorbitol, sorbitol, sorbitol, sorbitol, sorbitol, Chitosan, chitosan succinamide, vitamin E (tocopherol), urea, hydroxy, carboxymethyl chitin, ceramide, glucosyl ceramide, glycosaminoglycan, alpha-glucan, hyaluronic acid, hydrolized hyaluronic acid, Ethyl urea, glucosides, gamma PGA, xylityl glucoside, xylitol, pentaerythritol tetraisostearate, sodium chondroitin sulfate, Sodium polygamma-glutamate, polyglutamic acid, glyceryl polyacrylate, galactoarabanane, polyglycerin-3, polyglycerol-3, But are not limited to, crosspolymer, sodium hyaluronate, bis-phage-18 methyl ether dimethylsilane, bis-ethoxydiglycol stearate, lecithin, ascorbyl tetraisopalmitate, glycosyltrehalose, Citrate, glycogen, histidine HCI, alanine, threonine, glutamic acid, lysine HCI, phosphate buffered cellulain, creatine, cholecysteine, Stearyl isostearate, cholesteryl chloride, cholesteryl nanoate, VITECH, sodium diureamidoglutamide Shin, maltodextrin, polyquaternium -39, Collet knife when not fetch rolpi -12 ethers, saccharide iso Murray rate, but sorbitol, and be at least one selected from the group consisting of a derivative thereof, but is not limited thereto.

The ultraviolet shielding component may be selected from ultraviolet absorbing agents such as p-aminobenzoic acid derivatives, cinnamic acid derivatives, salicylic acid derivatives and benzophenone derivatives, ultraviolet light scattering agents such as titanium oxide and zinc oxide, cellulosic, A silicone resin, a fluorine-modified silicone resin, and the like, and a polymer film-forming agent. Examples of the components having an actual ultraviolet shielding function include, for example, cinnamic acid, glyceryl paraben, drometrizole, digallol trioleate, 3, (4-methylbenzylidene) campa, menthyl anthranilate, , Benzophenone-4, benzophenone-8, butylmethoxybenzoylmethane, cyoxsite, adenine riboside, octocrylene, octyldimethylpara, octylmethoxycinnamate, octyl salicylate, octyltriazone, paraamino Benzoic acid, benzoimidazole-5-sulfonic acid, homosalate, zinc oxide, titanium dioxide, isoamyl-p-methoxy cinnamate, bisethylhexyloxyphenol methoxyphenyltriazine, disodium phenyldibenzimide (Dimethicodimethylbenzalmalonate), methylenebis-benzotriazolyltetramethylbutylphenol, terephthalic acid, terephthalic acid, terephthalic acid, terephthalic acid, Dendy Camposulphone And be at least one selected from the group consisting of a salt thereof, but is not limited thereto.

The fragrant component includes, for example, aldehydes, phenols, alcohols, ethers, esters, hydrocarbons, ketones, lactones, screw, terpene skeleton, natural fats and animal fats . Examples of the aldehydes include, but are not limited to, undecylenaldehyde, laurylaldehyde, aldehyde C-12MNA, amalacaldehyde,? -Amylcinnamic aldehyde, ethyl vanillin, Aldehyde,? -Hexylcinnamaldehyde, octanal, ligustral, lily, ralal, triplal, vanillin, heliolal and the like. Examples of the phenols include, but are not limited to, ogenol, isoeugenol, and the like. Examples of the alcohols include, but are not limited to, glutaraldehyde, dihydromyrcenol, dihydrolinalol, linalool, nerol, acid valerate, santalex, terpineol, , Phenylethyl alcohol, and the like. Examples of the ethers include, but are not limited to, Sedramba, Glysalba, methyl ogenol, methylisoisoenol, and the like. Examples of the esters include, but are not limited to, cis-3-hexenylacetate, cis-3-hexenylpropionate, cis-3-hexenyl salicylate, p- Benzyl salicylate, benzyl benzoate, benzyl acetate, cedar acetate, citronelylacetate, decahydro-p-naphthylacetate, methylcyclohexyl acetate, amyl acetate, methyl dihydrozamate, , Dimethylbenzylcarbinyl acetate, erica propionate, ethyl acetoacetate, erica acetate, geranyl acetate, geranyl formate, herdion, linalyl acetate,? -Phenyl ethyl acetate, hexyl salicylate, styryl acetate Butyl acetate, isobutyl acetate, isopropyl acetate, isobutyl acetate, isobutyl acetate, The site can be like. Examples of the hydrocarbons include, but are not limited to, myrcene and the like. Examples of the ketones include, but are not limited to, α-ionone, β-ionone, methyl-β-naphthyl ketone, α-damascone, β-damascone, δ-damascone, , Methylionone, allylionone, cashemenol, dihydroadzone, iso super, bertopics, isolon zipporanone, corbone, rose penone, raspberry ketone, dynascon and the like. Examples of the lactones include, but are not limited to,? -Decalactone,? -Undecaractone,? -Nonaracetone,? -Dodecalactone, coumarin, and anbrocano. Examples of the screw include, but are not limited to, cyclopentadecanolide, ethylene brassylate, galactosol, musk ketone, tonalide, and nitromuscule. Examples of the gluten having the terpene skeleton include, but are not limited to, geraniol (geraniol), nerol, linalool, citral, citronellol, menthol, mint, citronellal, , Pinene, limonene, terpineolol, carbone, yonon, camphor, borneol, and the like. Examples of the natural flavoring include, but are not limited to, orange oil, lemon oil, lime oil, petit grain oil, oil free, neroli oil, bergamot oil, lavender oil, lavandin oil, The present invention relates to a medicinal herb such as a herb, a bouillard oil, a ylang ylang oil, a citronellular oil, a geranium oil, peppermint oil, peppermint oil, spearmint oil, eucalyptus oil, lemon grass oil, , Essential oils such as osmosis oil, pine oil, camphor oil, petunia oil, persimmon oil, terfen oil, clove oil, black clove oil, cacao oil, nutmeg oil, canal oil, and time oil. Examples of the animal fats include, but are not limited to, musk, marjoram, hazel flavor, miscellaneous flavor, and the like.

The dye is a chromophore having at least one atomic group selected from the group consisting of -NO ₂ , -N═N-, C═O, C═C, C═N-, C═S, -N═O and -N═NO But are not limited thereto. Further, the dye may be a dye having a chromophore group consisting of -OCH ₃ , -N (CH ₃ ) ₂ , -NH (CH ₃ ), -NO ₂ , -CF ₃ , -OH, -OCH ₃ , -Cl and -NH ₂ But are not limited to, one or more atomic groups selected from the group. Further, the dye is _{-COONa, -COOK, -COOH, -NH 2} , -NHR, -NR 2, -Cl, -Br, but may include one or more reactors selected from the group consisting of -F and -I, But is not limited thereto. The dyes may be natural dyes or synthetic dyes used for hair, skin, fibers, leather, etc., and the natural dyes may be purpurin, Munjistin, Melanin or melanin precursor , And the synthetic dyes include red 3, red 104, red 105, red 201, red 202, red 220, red 227, black 401, red 230, red 231, Red No. 232, Red No. 401, Red No. 405, Yellow No. 4, Yellow No. 202, Voltage No. 207, Red No. 106, Red No. 213, Red No. 214, Red No. 215, Amber No. 404, Amber No. 405, Disperse Blue 1, Disperse Violet 1, Disperse Orange 3, Disperse Black 9, and HC Blue 2, ), HC Red 3, HC Yellow 5, HC Red 1, Basic Orange 1, Bay 1, Orange, but 2 days, but it not limited thereto.

The bioadhesive component may include fibrin, albumin, glucosamine, n-acetylglucosamine, alginate, hydrogel, growth factors, physiologically active factors, glue binders, antimicrobial coatings and the like. Examples of the growth factor include FGF (Fibroblast Growth Factor), Keratinocyte Growth Factor (KGF), Vascular Endothelial Growth Factor (VEGF), Epidermal Growth Factor (EGF), Platelet Derived Growth Factor AA -AB (Platelet Derived Growth Factor AB), PDGF-BB (Platelet Derived Growth Factor BB), TGF-alpha (Transforming Growth Factor-?), TGF-beta, Insulin-like Growth Factor (IGF), Tumor Necrosis Factor ), GM-CSF (Granulocyte Macrophage Colony Stimulating Factor), NGF (NGF (Nerve Growth Factor)), etc. The physiologically active factors include interferon, erythropoietin, 1L- , IL-6, IL-8, etc. The glue conjugate may be N- (4-carboxy-3-hydroxy-phenyl) maleimide, transglutaminase, lauryldiamine, Benzalkonium chloride, benzethonium chloride, halocarbane, 2,4,4-trichloro-2-hydroxyphenol, triclosan, trichlorocarbide, isoprop Methylphenol, pinion, allantoin, ε- aminocaproic acid, or the like, but glycidyl chili parent acids, but is not limited thereto.

Wherein the antimicrobial component is selected from the group consisting of ceramide, glycerin, hyaluronic acid, betaine, chitosan, vitamin E (tocopherol), Urea, d- panthenol, sulfur, lesionsin, serine, allantoin, AHA, salicylic acid, Benzoquinone chloride, benzethonium chloride, chlorohexidine, hinocidol, phenol, isopropylmethylphenol, phenoxyethanol, isothiazolinone, methylchloroisobutyrate, methylcyclohexanone, (Stearyl Glycyrrhetinate (Glycyrrhizinate), Glycyrrhizinate, Glycyrrhizinate, Glycyrrhizinate, Glycyrrhizinate, Glycyrrhizic Acid, Hydrocortisone Acetic Acid, Hydrocortisone Succinate, Prednisolone, Chlorophenylamine Hydrochloride, Chlorophenylamine Maleate, Campa, Menthol, Alanine Glutamine, Bisabolol, ) / DPG (dipotassium Glycyrrhizinate), phytosphingosine and derivatives thereof, and the like.

The wool, hair growth or hair growth component may be selected from the group consisting of common extract, caproium chloride, cephalanthin, benzyl nicotinate, l-menthol, estradiol, ethinyl estradiol, pyridoxine hydrochloride, salicylic acid, resorcin, The present invention relates to a method for the production of glycyrrhetinic acid, which comprises administering to a patient in need thereof a therapeutically effective amount of a compound selected from the group consisting of benzethonium chloride, isopropylmethylphenol, pylontonolamine, climbazole, pantothenic acid, placenta extract, biotin, mononitroguacol, (Acetic acid) hydrocortisone, prednisolone, diphenhydramine hydrochloride, dipotassium glycyrrhizinate, pyridoxine dicarboxylate, tricosaccharide, tocopherol / tocopherol acetate, hinokitiol, Dexpanthenol, pantothenyl ethyl ether, sodium pantothenate / calcium, isopropyl ethyl phenol, mononitroguacol, gluconate chlorocarbonate A cholesterol, a sulchiol, a soluble cystine, a ginseng tincture, a seschin tincture, a hypocotyl extract, a frequently used pectin, a cefalcin, a gamma-oryzarol, a kantarystin, vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin E, cystine, cysteine, methionine, leucine, tryptophan, glycerin, pyrrolidone carboxylic acid, camphor and derivatives thereof, etc. But are not limited thereto.

The hair surface modifying component is preferably used in an amount of 0.0001 to 50 parts by weight, 0.001 to 30 parts by weight, 0.01 to 10 parts by weight, or 0.1 to 5 parts by weight based on 100 parts by weight of the entire cosmetic composition. When the content thereof is less than 0.0001 part by weight, there is a limit in providing an effect by the active ingredient. When the content is more than 50 parts by weight, there is a problem in stability of formulation and formulation with time,

Particularly, in the present invention, the hair surface modifying component can increase the reaction efficiency with the carbodiimide compound by including a carboxyl group, a hydroxyl group, a phosphate group or an amine group in the molecule.

In addition, in the present invention, the hair surface modifying component may further include a component having a functional group capable of covalently bonding to protein residues on the surface of hair or having a functional group capable of forming a covalent bond with a protein residue on the surface of hair.

The functional groups covalently bonded to the protein residues include carbodiimide, imidoesters, aryl azides, diazylines, hydroxymethylphosphines, pentafluorophenyl esters, pyridyl disulfides, sulfo-hydroxysuccinimide esters, alkoxyamines , Hydrazide, haloacetyl, azide, carbonate, aldehyde, propionaldehyde, butylaldehyde, nitrophenyl carbonate, aziridine, isocyanate, thiocyanate, epoxide, tresylate, succinimide, At least one member selected from the group consisting of ester, imidazole, oxycarbonylamidazole, imine, thiol, maleimide, vinylsulfone, ethyleneimine, thioether, acrylonitrile, acrylic acid or methacrylic acid ester, disulfide and ketone But is not limited thereto.

In addition, the functional group may react with thiol, hydroxyl, carboxyl or amine residues of amino acids constituting the protein.

In one preferred embodiment of the hair surface modifying composition according to the present invention, a hair surface modifying component having a carboxyl group is directly made into a form of a surface modifying component of a reactive ester hair having a bioreactivity, or an excessive amount of hair (17.5 to 21.9% Reactive esterification of amino acids (ex, aspartic acid, glutamic acid) to produce reactive ester forms (reactive hair surface modifying components) using carbodiimide compounds that can be targeted by hair surface modifying components including amine groups, The effect can be remarkably increased. In addition, it is also possible to use carbodiimide, imidoesters, aryl azides, diazylenes, hydroxymethylphosphines, pentafluorophenyl esters, pyridyl disulfides, sulfo-hy- droides, etc. which target other amino acids or enhance the carbodiimide reaction It is possible to further enhance the effect by using a hair surface modifying component containing a functional group such as a hydroxy-succinimide ester, hydroxy succinimide ester, alkoxyamine, hydrazide, haloacetyl, or azide in the molecule.

In a more preferred embodiment, a polymeric carbodiimide compound of the formula (1) is firstly reacted first on the surface of a hair surface modifying component molecule having a carboxyl group or hair to form a reactive ester, and then an amine is reacted with the reactive ester functional group formed An excellent hair surface modifying effect can be obtained by reacting a hair surface modifying component contained in the molecule or by reacting with an amine on the hair surface. The reaction is preferably carried out at a pH of from 2 to 10, more preferably at a pH of from 3 to 9, and most preferably at a pH of from 4 to 6.5 in an acidic to slightly acidic aqueous solution The reaction efficiency can be increased most. The reaction is completed within 1 minute to 30 minutes.

In the following reaction scheme 1, a hair surface modifying component molecule having a carboxyl group is firstly reacted with a carbodiimide compound to form a reactive ester, followed by reaction with an amino acid having an amine residue to form a covalent bond.

[Reaction Scheme 1]

In the following Reaction Scheme 2, asparaginic acid and glutamic acid, which are carboxylamino group-bearing biogenic amino acids on the protein surface of hair, first react with a carbodiimide compound to form a reactive ester, and then react with a hair surface modifying component having an amine residue to form a covalent bond .

[Reaction Scheme 2]

The carbodiimide compound increases the reaction efficiency of the hair protein and the hair surface modifying component so that the reactive hair surface modifying component bound to the hair or the skin does not fall off well during general washing due to shampoo or soap, It can be kept attached to hair or skin.

The present invention also relates to a hair surface modifying composition comprising at least one compound selected from the group consisting of carbodiimide groups, imidoesters, aryl azides, diazylenes, hydroxymethylphosphines, pentafluorophenyl esters, pyridyl disulfides, sulfo- But are not limited to, alkoxyamine, hydrazide, haloacetyl, azide, carbonate, aldehyde, propionaldehyde, butylaldehyde, nitrophenyl carbonate, aziridine, isocyanate, thiocyanate, epoxide, tresylate, succinimide, One selected from the group consisting of an imidyl ester, imidazole, oxycarbonylamidazole, imine, thiol, maleimide, vinylsulfone, ethyleneimine, thioether, acrylonitrile, acrylic acid or methacrylic acid ester, disulfide and ketone A reactive hair surface modifying component having a functional group covalently bonded to the above protein May be further included.

In addition, the present invention may include a hair surface modifying composition comprising the reactive hair surface modifying component.

In order to further enhance the effect of formulating the hair surface modifying composition according to the present invention into cosmetics, fatty acids such as palmitic acid and stearic acid, fatty alcohols, long-chain alkyl quaternary When mixed with a cationic surfactant such as an ammonium salt, a cationized cellulose, a cationic guar, a cationic polymer such as cationized polyvinylpyrrolidone, silicone, etc., formulation can be facilitated. In order to formulate cosmetics such as solvents, surfactants, thickeners, stabilizers, preservatives, coloring agents, pH adjusters, metal ion sequestering agents, coloring agents, pearlizing agents, external appearance improvers, pigments and powder particles, Components may be incidentally included. The components for the formulation may be used in an amount of 0.0001 to 30 parts by weight based on 100 parts by weight of the total composition.

The hair surface modifying composition according to the present invention can be used in the hair care product prescription including the hair surface modifying component having the functional group. Hair care products include shampoos, rinse, trimming, hair pack, hair essence, wax, gel, spray, mousse, hair dye, decolorant, And may include all agents that can be used in hair, such as formulations.

More preferably, the hair surface modifying composition according to the present invention comprises a hair surface modifying component containing a carbodiimide compound and at the same time having a reactive functional group (particularly an amine or carboxyl group, a hydroxyl group, a phosphate group) When the activity is lowered in a water-based system, it is easier to maintain its activity in a non-aqueous formulation, and a reaction occurs by mixing with a buffer for pH control just before use, or by contacting with water in a washing process . Examples of non-aqueous formulations include liquid, sheet, powder, tablet, oil, wax, ampoule, gel and the like which are used as ordinary non-aqueous cosmetic preparations. In addition, the carbodiimide compound and the hair surface modifying component can be formulated as a single agent in an encapsulated form or as two separate forms of each. In addition, a method of blocking a derivative in which a functional group having reactivity and a component having a hair surface modifying function is coupled through encapsulation from moisture can also be used.

In order to enhance the surface modifying effect of hair having a functional group in the hair surface modifying composition according to the present invention, it is preferred to use a mixture of a 2-basic acid ester oil such as dioctyl succinate, dioctyl adipate, diethyl sebacate and the like, a polyol, Glycol, hexylene glycol, butanediol and isomers thereof, glycerol, benzyl alcohol, ethoxydiglycol and derivatives thereof can be used. The above-mentioned solvents increase the permeability of hair and are used as a solvent of a poorly soluble substance. More preferably, the solvent used to increase the activity maintaining effect of the conditioning component having a functional group is diethyl sebacate, ethoxy glycol, bis-ethoxy glycol cyclohexane 1,4-dicarboxylate, and the like.

Hereinafter, the present invention will be described in detail by the following examples. However, the following examples are illustrative of the present invention, and the present invention is not limited to the following examples.

Comparative Example  1 to 8 and Example  1 to 4: Preparation of shampoo composition

In terms of composition and content shown in Table 1, stearylamidopropylamine, which is generally used as a conditioning component in hair shampoos, Phenyl Amodimethicone, which is used as a conditioning (hair shine) component, Comparative Examples 1 to 4, which contained poly (lysine) used as a conditioning (hair thickness increasing) component, chitosan polymer used as a hair moisturizing component and did not contain a carbodiimide polymer; Comparative Examples 5 to 8 including benzene, 1,3-bis (1-isocyanato-1-methylethyl) -, homopolymer and polyethylene glycol mono-Me-ether-blocked as the carbodiimide polymer; And the hair shampoo compositions of Examples 1 to 4 including the carbodiimide-based polymer of the present invention, 1,1'-methylene-bis- (3-isocyanatocyclohexane) -, homopolymer and polyethylene glycol mono-Me- .

division
(weight%) Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 Comparative Example 7 Comparative Example 8 Example 1 Example 2 Example 3 Example 4 Water 47 47 47 47 46 46 46 46 46 46 46 46 Polyquaternium-10 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 EDTA 4Na 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 Sodium Lauryl Ether (2 mole) Sulfate (30%) 35.0 35.0 35.0 35.0 35.0 35.0 35.0 35.0 35.0 35.0 35.0 35.0 Cocamidopropyl Betaine (30%) 15.0 15.0 15.0 15.0 15.0 15.0 15.0 15.0 15.0 15.0 15.0 15.0 incense 0.9 0.9 0.9 0.9 0.9 0.9 0.9 0.9 0.9 0.9 0.9 0.9 Stearylamidopropyl Amine 1.0 - - 1.0 - - 1.0 - - - Phenyl Amodimethicone - 1.0 - - 1.0 - - 1.0 - - Poly-Lysine - - 1.0 - - 1.0 - - 1.0 - Chitosan Polymer - - - 1.0 - - - 1.0 - - - 1.0 Benzene, 1,3-bis (1-isocyanato-1-methylethyl) -, homopolymer, polyethylene glycol mono-Me-ether-blocked - - - 1.0 1.0 1.0 1.0 - - - - 1,1'-methylene-bis- (3-isocyanatocyclohexane) -, homopolymer, polyethylene glycol mono-Me-ether-blocked - - - - - - 1.0 1.0 1.0 1.0 pH adjuster Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Sum 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0

Experimental Example  1: Check conditioning and moisturizing effect

 Each of the hair tresses having a length of 12 cm and a weight of 3 g was shampooed 10 times with the shampoo compositions of Examples 1 to 4 and Comparative Examples 1 to 8 to induce surface modification. Each of the tresses was washed with 15% of sodium lauryl ethyl sulfate, (5 points: Excellent, 4 points: Slightly superior, 3 points (5 points: Excellent), 4 points (Good: Excellent), and 3 points (Hair thickness measurement device using a laser), moisturizing (moisture level measurement), and the like), shine (using a hair gloss measuring device through measurement of light reflectance), hair thickness The results are compared in Table 2, and the results are shown in Table 2 below.

division Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 Comparative Example 7 Comparative Example 8 Example 1 Example 2 Example 3 Example 4 Conditioning effect 2.3 - - - 3.7 - - - 4.5 - - - Shiny increase rate (%) - 1.2 - - - 28 - - - 53 - - Thickness Growth Rate (%) - - 0.23 - - - 3.6 - - - 7.3 - Hair moisture content (%) - - - 10.3 - - - 17.2 - - - 25.6

As shown in Table 2, it was confirmed that the conditioning, gloss, hair thickness and moisturizing effect were significantly superior to those of Comparative Examples 1 to 8 in Examples 1 to 4 in which the present invention was applied.

Comparative Example  9-12 and Example  5 ~ 6: Preparation of shampoo composition

In the same contents as shown in the following Table 3, the hair shampoo generally contained red 227, which is used as a dye component, and lauryldiamine, which has a structure capable of joining cleaved hair, and contains a carbodiimide polymer Comparative Examples 11 and 12 in which benzene, 1,3-bis (1-isocyanato-1-methylethyl) -, homopolymer and polyethylene glycol mono-Me-ether-blocked were contained as carbodiimide- And the shampoo composition for hair of Examples 5 and 6 including the carbodiimide-based polymer of the present invention, 1,1'-methylene-bis- (3-isocyanatocyclohexane) -, homopolymer and polyethylene glycol mono-Me- .

Category (% by weight) Comparative Example 9 Comparative Example 10 Comparative Example 11 Comparative Example 12 Example 5 Example 6 Water 47 47 46 46 46 46 Polyquaternium-10 0.5 0.5 0.5 0.5 0.5 0.5 EDTA 4Na 0.05 0.05 0.05 0.05 0.05 0.05 Sodium Lauryl Ether (2 mole) Sulfate (30%) 35.0 35.0 35.0 35.0 35.0 35.0 Cocamidopropyl Betaine (30%) 15.0 15.0 15.0 15.0 15.0 15.0 incense 0.9 0.9 0.9 0.9 0.9 0.9 Red 227 1.0 - 1.0 - 1.0 - Lauryl Diamine - 1.0 - 1.0 - 1.0 Benzene, 1,3-bis (1-isocyanato-1-methylethyl) -, homopolymer, polyethylene glycol mono-Me-ether-blocked - - 1.0 1.0 - - 1,1'-methylene-bis- (3-isocyanatocyclohexane) -, homopolymer, polyethylene glycol mono-Me-ether-blocked - - - - 1.0 1.0 pH adjuster Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Sum 100.0 100.0 100.0 100.0 100.0 100.0

The white shampoos were shampooed 10 times each using the present shampoo composition Comparative Examples 9, 11, and 5. The shampoo composition Comparative Examples 10, 12, and Example 6 were used to shuffle 30 shredded hair each time with 10 shampoos And the surface of each tress was washed with a 15% solution of sodium lauryl ethyl sulfate as a cleaning surfactant three times to remove the covalent bonds and remove the adsorbed components. In the case of yachm, And the recovery of cracked hair was confirmed by the microscope in the case of the split hair, and the results are shown in Table 4 below.

division Comparative Example 9 Comparative Example 10 Comparative Example 11 Comparative Example 12 Example 5 Example 6 Red Growth Rate (%) 13 - 27 - 49 - Rate of splicing (%) - 0 - 35 - 48

As shown in Table 4, it was confirmed that the dyeing and bioadhesion effects of Examples 5 and 6 to which the present invention was applied were remarkably superior to those of Comparative Examples 9 to 12.

Formulation example  1: Conditioning shampoo manufacturing

The conditioning hair shampoo of Table 5 was prepared using the general hair shampoo manufacturing method.

Raw material content Water 44.6 Polyquaternium-10 0.5 EDTA 4Na 0.05 Sodium Lauryl Ether (2 mole) Sulfate (30%) 35.0 Cocamidopropyl Betaine (30%) 15.0 incense 0.9 Stearylamidopropyl Amine 1.0 1,1'-methylene-bis- (3-isocyanatocyclohexane) -, homopolymer, polyethylene glycol mono-Me-ether-blocked 1.0 pH adjuster Suitable amount Sum 100.0

Formulation example  2: hair  Product Manufacturing (Conditioning) mist , Lotion, cream, pack)

The conditioning hair products of Table 6 below were prepared using conventional hair conditioning mists, lotions, creams, and packs.

Component (% by weight) Conditioning mist Conditioning Lotion Conditioning Cream Conditioning Pack Stearylamidopropylamine One One One One Phenyl amodimethicone One One One One Polylysine One One One One Chitosan polymer One One One One 1,1'-methylene-bis- (3-isocyanatocyclohexane) -, homopolymer, polyethylene glycol mono-Me-ether-blocked One One One One glycerin 3 3 3 3 Butylene glycol 3 3 3 - Propylene glycol 3 3 - - Carboxyvinyl polymer 0.1 0.1 0.1 - Polyvinyl alcohol - - - 15 Phage-12 nonylphenyl ether 0.3 - - 0.5 Polysorbate 80 0.5 - - - Polysorbate 60 - 1.5 1.5 1.5 Sorbitacecequioleate - 1.5 - - Sorbitan stearate - - 0.5 - Liquid paraffin - 0.5 10 - Caprylic / capric triglyceride - 5 5 - Squalane - 5 5 - Cetearyl glucoside - - 2 - ethanol 10 - - - Triethanolamine 0.1 0.1 0.1 - Cetearyl alcohol - One - - Wax - 5 - - antiseptic Suitable amount Suitable amount Suitable amount Suitable amount Spices Suitable amount Suitable amount Suitable amount Suitable amount Purified water Buffer (pH 4.5) Balance Balance Balance Balance

Claims (9)

delete A carbodiimide compound represented by the following formula (2); And a hair modifying component,
Wherein the hair-modifying component comprises an antioxidant component; Conditioning component; UV blocking ingredients; Fragrance component; dyes; Bio junction components; Antimicrobial component; Or wool, hair growth or hair growth component:
(2)

In formula (2), A represents one or more monomers selected from the structures listed below and has isocyanate (*) groups at both ends of the repeating unit, wherein two A's are homopolymers having the same structure or different structures (N is an integer of 1 to 1000, and m is an integer of 1 to 100).

A carbodiimide compound represented by the following formula (3); And a hair modifying component,
Wherein the hair-modifying component comprises an antioxidant component; Conditioning component; UV blocking ingredients; Fragrance component; dyes; Bio junction components; Antimicrobial component; Or wool, hair growth or hair growth component:
(3)

In Formula 3, n is an integer of 1 to less than 120, and m is an integer of 1 to less than 100.
The method according to claim 2 or 3,
Wherein the hair modifying component comprises a carboxyl group, a hydroxyl group, a phosphate group or an amine group in the molecule.
The method according to claim 2 or 3,
Wherein the hair modifying component has a functional group capable of covalent bonding with a protein residue on the surface of hair.
6. The method of claim 5,
The functional groups capable of forming a covalent bond with the protein residue include imidoesters, aryl azides, diazines, hydroxymethylphosphines, pentafluorophenyl esters, pyridyl disulfides, sulfo-hydroxysuccinimide esters, alkoxy amines, And examples thereof include aliphatic hydrocarbons such as benzene, toluene, xanthan gum, zeolite, zeolite, haloacetyl, azide, carbonate, aldehyde, propionaldehyde, butylaldehyde, nitrophenylcarbonate, aziridine, isocyanate, thiocyanate, epoxide, Wherein the composition is at least one selected from the group consisting of at least one member selected from the group consisting of a hydroxyl group, a hydroxyl group, a hydroxyl group, a hydroxyl group, a hydroxyl group, a hydroxyl group, a hydroxyl group, a hydroxyl group, .
The method according to claim 2 or 3,
Wherein the carbodiimide compound is 0.0001 to 10 parts by weight per 100 parts by weight of the total composition.
The method according to claim 2 or 3,
The carbodiimide compound and the hair-modifying component are formulated into a single preparation in an encapsulated form; Wherein the carbodiimide compound and the hair modifying component are separated from each other.
A hair care product comprising the hair surface modifying composition of claim 2 or 3.