KR101736478B1 - Method for manufacturing lotions with effective in treating acne - Google Patents

Abstract

The present invention relates to a method for producing a lotion which is effective for the treatment of acne, and more particularly, to a method for producing a lotion which is effective for treating skin itching and acne by alleviating dry and rough skin and lchthyosis vulgaris by utilizing ammonium lactate. And to a method for manufacturing lotions.

Description

Technical Field [0001] The present invention relates to a method for manufacturing an acne-treating lotion,

The present invention relates to a method for producing a lotion which is effective for the treatment of acne, and more particularly, to a method for producing a lotion which is effective for treating skin itching and acne by alleviating dry and rough skin and lchthyosis vulgaris by utilizing ammonium lactate. And to a method for manufacturing lotions.

As is well known, when cells are damaged or deteriorated due to changes in regulation, medication, surgery, food, environmental conditions, chemical and physical factors, pressure, temperature, pH, etc., mitochondria Of ATP is reduced.

At this time, the core temperature is lowered, and in the hypothalamus, which is the central body of temperature control, the pores are closed to reduce sweat discharge to preserve and maintain the body temperature.

However, when the pores are closed, the daily work, the excessive work, the stress, the meal, the exercise, etc., are reduced, and the skin is reduced as the water is supplied to the skin. As a result, When it occurs, it is diagnosed as lchthyosis Vulgaris.

These imaginary lines begin with dry skin and eventually itch.

In this regard, a medical treatment called pereethetherapy is being carried out, which is the main concept of increasing the temperature of the deep part, lowering the skin temperature and smoothing the pore opening and closing.

In addition, medication therapy, diet, lifestyle therapy and exercise therapy are accompanied by professional and intensive and continuous management is possible only through time, busy daily life, Is a difficult treatment to treat unless accompanied by extreme pain.

Therefore, many lotion type skin moisturizers that can be easily contacted and used even in the busy daily life of the general public have been developed and on the market.

However, they are limited to the skin moisturizing function, and it is too expensive for a product having an effect of alleviating itching and prolonging the time for preventing dryness of the skin, which is a very expensive cost to the general public.

In addition, as the skin becomes dry, the activity of the sebaceous glands is stimulated and an excessive amount of sebum is secreted, which is directly related to the generation of acne.

Of course, in relation to acne, hormonal abnormalities, irregular eating habits, and excessive stress can also be caused by a complex action. However, the most fundamental and fundamental cause of acne is the skin dryness.

Korean Patent Registration No. 10-1419621 (Apr. 20, 2014), "Wipes Containing Lotion Composition Containing Omega-6 Fatty Acids" Korean Patent Laid-Open No. 10-2005-0000693 (2005.01.06.), 'External skin preparation having skin moisturizing and anti-inflammatory effect' Korean Patent Registration No. 10-1015909 (Feb. 11, 2011), 'Cosmetic Composition for External Skin Containing Chi- Korean Patent Laid-Open No. 10-2015-0070100 (June 25, 2014), "Cosmetic or pharmaceutical moisturizing ingredient" Korea Patent Registration No. 10-0357824 (Oct., 2002), 'Cosmetics containing natural products effective for the treatment and prevention of acne' Korean Patent Publication No. 10-0861978 (Sep. 30, 2008), 'Cosmetic Composition for Treatment of Acne Using Azelaic Acid and Method for Producing the Same' Korean Patent Laid-Open No. 10-2012-0052991 (May 24, 2012), "Cosmetic composition for treating acne including omiza peptide extract" Korean Patent Registration No. 10-0981038 (Sep. 1, 2010), "Composition for treating atopy and acne"

The present invention has been made in view of the above-described problems in the prior art, and it is an object of the present invention to provide a method for treating skin irritation and acne by using ammonium lactate to alleviate dry and rough skin and lchthyosis vulgaris, The present invention is directed to a method for manufacturing a lotion.

Disclosure of the Invention In order to achieve the above-mentioned object, the present invention provides a method for producing a water-based cosmetic composition, comprising: a dispersion step of mixing a lotion composition as a solvent at low speed; An emulsifying step of heating the dispersion obtained in the dispersing step to 50-60 캜 and cooling to room temperature to keep the viscosity stably; A mixing step of adding a pigment, a brightener and a functional pigment to the emulsified emulsion; A packaging step of filling the mixed lotion with a container and packaging the mixed lotion; In the dispersion step, a dispersion solution obtained by mixing and dispersing a lotion composition as a solvent in a solvent is mixed with 5 wt% of ammonium lactate, 2 wt% of glycerin, 3 wt% of propylene glycol, 0.5 wt% of trehalose, 0.2 wt% of xanthan gum, 1% by weight of a clay compound prepared by mixing kaolin and montmorillonite having a particle size of -2 탆 in a weight ratio of 1: 1, 3.5% by weight of glyceryl stearate as an emulsifier, 12% by weight of ester oil, citrus peel, 2% by weight of complex fermented extract, 0.5% by weight of preservative, 0.5% by weight of aroma oil, 0.5% by weight of pH adjusting agent 0.5% by weight of corn oil, 1: 1: 1: 1 by weight of a mixed microorganism, By weight, and the remaining purified water. The present invention also provides a method for producing an effective lotion for treating acne.

At this time, the purified water used as the solvent used in the dispersion step was prepared by mixing distilled water heated at 50-50 ° C with 50% by volume of filtered water obtained by filtering a mixture of tourmaline powder and talc powder mixed at a weight ratio of 2: 1 ; And 50 vol% of alkaline ion electrolytic reduced water obtained by electrolysis of tap water.

The dispersion step is also characterized in that it is configured to stir at 100-200 rpm for 10-15 minutes.

According to the present invention, ammonium lactate can be used to alleviate dry and rough skin and lchthyosis vulgaris, and skin itching and acne formation inhibiting effect due to skin moisturization can be obtained.

Hereinafter, preferred embodiments according to the present invention will be described in detail.

Before describing the present invention, the following specific structural or functional descriptions are merely illustrative for the purpose of describing an embodiment according to the concept of the present invention, and embodiments according to the concept of the present invention may be embodied in various forms, And should not be construed as limited to the embodiments described herein.

In addition, it should be understood that the embodiments according to the concept of the present invention include various modifications, equivalents, and alternatives included in the spirit and technical scope of the present invention, .

A method for preparing a lotion having efficacy for treating acne according to the present invention comprises: a dispersion step of mixing a lotion composition as a solvent at low speed into purified water as a solvent; An emulsifying step of heating the dispersion obtained in the dispersing step to 50-60 캜 and cooling to room temperature to keep the viscosity stably; A mixing step of adding a pigment, a brightener and a functional pigment necessary for the emulsified emulsion; And a packaging step of filling the mixed lotion into a container and packaging the mixed lotion.

At this time, the purified water used as the solvent used in the dispersion step was prepared by mixing distilled water heated at 50-50 ° C with 50% by volume of filtered water obtained by filtering a mixture of tourmaline powder and talc powder mixed at a weight ratio of 2: 1 ; An electrolytic reduced water of alkaline ion obtained by electrolysis of tap water, that is, 50 vol% of alkaline ionized water is used.

Here, tourmaline is a silicate mineral that contains selenium, magnesium, boron, silicon, and silver, which have cell activation, skin and mucous strengthening, relieve itching, inhibit skin troubles and antioxidants. Used for; Talc is a monoclinic basic magnesium silicate mineral which is added to achieve skin mucosal protection, detoxification and anti-inflammatory function, in particular to prevent excessive skin moisturization.

Alkali ionized water is used in the present invention because blood in the body is weakly alkaline, and therefore, absorption is rapid and it is effective to supply minerals and the like to the skin to keep the skin moist.

In addition, the lotion composition as a solvent is composed of ammonium lactate, glycerin, propylene glycol, trehalose, xanthan gum, clay compound, emulsifier, ester oil, complex fermentation extract, preservative, aroma oil and pH regulator; The dispersion in which the lotion composition as a solvent is mixed and dispersed in the solvent is composed of 5 wt% of ammonium lactate, 2 wt% of glycerin, 3 wt% of propylene glycol, 0.5 wt% of trehalose, 0.2 wt% of xanthan gum, 1% by weight of a clay compound prepared by mixing kaolin and montmorillarite in a weight ratio of 1: 1, 3.5% by weight of glyceryl stearate as an emulsifier, 12% by weight of an ester oil, citrus peels, : 1, the complex microorganism was added and the mixture was extracted after fermentation, and then the mixture was composed of 2% by weight of the combined fermented extract of lyophilized powder, 0.5% by weight of preservative, 0.5% by weight of aroma oil, 0.5% .

Ammonium lactate is a synthetic substance that maximizes the original function of lactic acid by neutralizing the oxidized lactic acid by adding ammonium to lactic acid and contains lactic acid having excellent natural moisturizing function, Provides excellent moisturizing effect for sun, atopy and dry skin.

In the present invention, 5% by weight is added in order to enhance skin dryness inhibition by rapidly melting at 18 DEG C and rapidly absorbing moisture from the atmosphere and rapidly absorbing the skin.

The glycerin is a wetting agent containing a fat component. The glycerin absorbs moisture in the air and replenishes moisture to the skin, thereby moisturizing the dry skin and thereby reducing sebum production thereby suppressing the occurrence of acne. For this, in the present invention, it is added in the range of 2 wt%. If it is added in an excess amount in excess of 2 wt%, the adverse effect of moisture escaping from the skin occurs.

In addition, the propylene glycol is added in order to suppress the growth of fungi and to impart antimicrobial properties while supporting excess of glycerin. However, if it exceeds 3% by weight, skin irritation may be caused, so that it should be limited to the above range.

In addition, Trehalose belongs to the disaccharide, and is added for the purpose of preserving the moisture of the skin such as protein, lipid and the like while keeping the moisture very strong. However, it is preferable to not add more than 0.5 wt.

In addition, the Xanthan Gum is a mixture containing glucose, mannose, and sodium, potassium and calcium salts of mannose and glucuronic acid after purifying the polymer polysaccharide gum obtained by fermentation into isopropyl alcohol, followed by drying and pulverization . In the present invention, a minor amount of surfactant and emulsifying agent are added for skin conditioning. That is, when the content exceeds 0.2% by weight, the viscosity is greatly increased to inhibit solubilization.

The clay compound is a mixture of kaolin and montmorillonite in a weight ratio of 1: 1, which is a kind of silicate, which is a fine particle (1-2 탆) and suitable for smooth and white color development. In particular, in the case of montmorillonite, It is added for the function of activating the cells in the skin by radiation to inhibit sebaceous formation and to prevent the skin from drying out and turning into imaginary young lines.

In addition, the above-mentioned emulsifier is preferably a substance which makes two kinds of liquids which are not mixed with each other into a stable emulsion (emulsion), and glyceryl stearate. However, if it exceeds 3.5% by weight, the emulsion will be excessively formed, so that it should be limited to the above range.

In addition, the ester oil is a moisturizing and skin coating agent, which forms a film in a moist state in a state of supplying an influence to the skin, thereby suppressing the occurrence of sebum by blocking skin psoriasis, thereby preventing the occurrence of acne and preventing itching do. However, if it is more than 12% by weight, skin softening is inhibited, and therefore, the use should be limited to the above range.

In addition, the complex fermentation extract is added for skin soothing effect, and the complex microorganism is added in a weight ratio of 1: 1: 1: 1 of citrus peel, bokbunja, It is a natural vegetable fermented extract in a dry powder form.

In addition, the preservative is added in a trace amount for the purpose of preservation, and imidazolidinyl urea is preferable. The aroma oil is a vegetable oil and is added as a vegetable oil in order to prevent the moisture coming from the skin surface from evaporating, And triethanolamine, which is a weakly alkaline buffering agent, is added to adjust the pH of the pH adjusting agent.

In addition, to further realize the functionality, 2 parts by weight of water-based ginseng powder (0.1-0.2 mu m), 2 parts by weight of Aronia powder (0.1-0.2 mu m), 2 parts by weight of isopropyl myristate 2 parts by weight of petrolatum, 1.5 parts by weight of petrolatum, 0.5 part by weight of carbomer, 5 parts by weight of raw chloe extract and 3 parts by weight of phytosphingosine.

In this case, the water-based ginseng powder is obtained by hydroponically cultivating ginseng and then drying and pulverizing it. It is possible to make a series as compared with the cultivation of the soil, and it is possible to cultivate environmentally friendly without pollution and saponin content is 14.3 -15.8mg / g, and the leaf is 140.8-180mg / g, which is 9 times higher than rhizome, and contains vitamin C of 65.9mg / g or more, so that it is possible to use all of leaves, stems and roots.

Especially, saponin is a generic name of glycosides containing agaric acid as a triglypene and steroid distributed in the vegetable field. It is known that ginseng contains 22 kinds of saponin. Among them, Rh2 ginsenoside and Rh1 ginsenoside have skin immunity It is known that it has excellent strengthening and soothing effect and is excellent at atopy sedative function. Moreover, oleic saponin is known to enhance heat retention, skin soothing effect and immunity.

The Aronia is a deciduous shrub of Rosaceae and has a very high content of polyphenols and anthocyanins, and thus has excellent antioxidant capacity (ORAC: Oxygen Radical Absorbent Capacity). The fruit has a skin antioxidant effect, collagen synthesis The effect of reducing skin wrinkles, the effect of preventing acne and the effect of reducing inflammation have been reported to be excellent.

In addition, the isopropyl myristate is added to provide flexibility as an ester of isopropyl alcohol and myristic acid; The petrolatum is a white ointment-like substance composed mainly of amorphous solid hydrocarbons and is waterproof and added to protect the skin by forming a film on the skin; The carbomer is added to give skin a cooling sensation.

In addition, Live Chlorella is a kind of plankton living in freshwater. Although it is a single-celled organism with a diameter of 2-10 μm, it has much more chlorophyll than ordinary plants, and its photosynthesis activity is active. -8 divided into 55% of high-quality protein and nutrients essential to the human body, as well as fiber, essential amino acids are abundant, CGF is a creature that contains a large amount of growth-promoting factors.

Such raw chlo is excellent in fat decomposition and sugar disinfection ability of meat and promotes cell activation, thus enhancing the immunity of the human body, and has the ability to neutralize heavy metals and toxins. However, simple addition is difficult, and it should be constructed so as to increase the safety through the addition of the extractive water addition method. As a method of generating the raw chloe extract water, the raw chloe is left in the purified water for 8-10 hours, .

The above-mentioned phytosphingosine is a lipid having a structure similar to bio-lipid, which is added in order to prevent skin damage due to the inhibition of acne occurrence and increase the skin barrier effect to inhibit infection.

On the other hand, the dispersion step should be stirred at a low speed, and it is preferable to stir at 100-200 rpm for 10-15 minutes in order to form a homogeneous dispersion.

Thereafter, the dispersion is commercialized through the above-described emulsification step, mixing step, and packaging step.

In this case, the reason for heating to 50-60 占 폚 in the emulsification step is to promote emulsification while preventing the undissolved components from occurring in the water-soluble substance.

Hereinafter, examples will be described.

[Example 1]

The lotion is made by the manufacturing method according to the present invention, wherein the dispersion contains 5 wt% of ammonium lactate, 2 wt% of glycerin, 3 wt% of propylene glycol, 0.5 wt% of trehalose, 0.2 wt% of xanthan gum, 1: 1: 1: 1 mixture of 1% by weight of a clay compound obtained by mixing 1: 1 and montmorillonite in a weight ratio of 1: 1, 3.5% by weight of glyceryl stearate as an emulsifier, 12% by weight of an ester oil, citrus peels, 1, the complex microorganism was added, followed by extraction after fermentation. The resulting mixture was then lyophilized to prepare 2% by weight of complex fermented extract, 0.5% by weight of preservative, 0.5% by weight of aroma oil, 0.5% by weight of pH adjusting agent and remaining purified water .

[Example 2]

2 parts by weight of water-based ginseng powder (0.1 to 0.2 mu m), 2 parts by weight of Aronia powder (0.1 to 0.2 mu m), 2 parts by weight of isopropyl myristate, 1.5 parts by weight of petrolatum, 0.5 parts by weight of carbomer, 5 parts by weight of raw chloe extract and 3 parts by weight of phytosphingosine were further added to the above dispersion.

In order to confirm whether or not the lotion according to the present invention is effective in alleviating acne and juvenile acne, 40 juveniles (20 males and 20 females) aged 18 to 20 years were selected, The lotion was applied to the affected part and the change in the affected part was confirmed for 2 months. Especially, for comparison, 'Avino Skin Relief Body Lotion 354ml (Korea Johnson & Johnson, manufactured in 2016)', a commercially available skin moisturizer, was divided into comparative examples.

At this time, the improvement effect of the acne and the imaginary line was photographed and stored as a reference image for the reference lesion (forehead, back, nose) of 40 persons, and after 2 months, the reference lesion of all 40 persons was imaged again After 3 - dimensional image analysis, the reference image and the comparative image were compared and analyzed on a micro scale. Of course, daily skin conditions were also confirmed by the eye and recorded as changes. In this case, the lotion of Example 1 was applied to the forehead, the comparative example was applied to the back, and the lotion of Example 2 was applied to the nose.

Here, 3D image analysis is a well-known method of analyzing the changes in the shape of the contour pattern, acne, and imaginary lines of the lesion to the micro-scale through the Machine Vision Algorithm.

As a result of analysis, it was confirmed that occurrence of sebum was significantly reduced in the forehead and nose of the lotions of Examples 1 and 2, and occurrence of acne was alleviated, and it was also confirmed that the skin dryness was alleviated and the skin cracks (imaginary lining) were remarkably reduced.

On the other hand, in the case of the comparative example, in addition to the general moisturizing function, the improvement of the treatment was not effective and the improvement of acne was not found. In the case of 3 women and 5 men,

In addition, in order to confirm the occurrence of skin trouble, the stability of lotion was tested through a skin patch test.

At this time, the test subjects were tested at the same time in the test group of the above-mentioned test group 40 in the test of the acne and dermal tenderness change, and after the lotion of Examples 1, 2 and Comparative Example was applied to the skin for 24 hours, The degree of stimulation was determined by a sensory test.

As a result, the average of the sensory scores of the skin was 0, 0, and 5, respectively. As a result, skin irritation was extremely small at 0.5 and 0.6 in Examples 1 and 2 , And 2.5 for the comparative example.

In addition, although it was visually confirmed whether inflammation, rash, erythema and itching occurred in the patch area, no inflammation, rash, erythema or itching occurred in Examples 1 and 2. However, in the case of the comparative example, four women were accompanied by skin swelling and itching.

Through such evaluation results, although the lotion according to the present invention can not fundamentally cure acne and juvenile glands, it moisturizes the area around the affected area and activates the skin cells to prevent excessive secretion of sebum, To calm the skin and to alleviate acne and imaginary lines.

Claims (3)

A dispersion step of mixing the lotion composition as a solvent at low speed with purified water as a solvent; An emulsifying step of heating the dispersion obtained in the dispersing step to 50-60 캜 and cooling to room temperature to keep the viscosity stably; A mixing step of adding at least one of a pigment, a polishing agent and a functional pigment to the emulsified emulsion; A packaging step of filling the mixed lotion with a container and packaging the mixed lotion;
In the dispersion step, a dispersion solution obtained by mixing and dispersing a lotion composition as a solvent in a solvent is mixed with 5 wt% of ammonium lactate, 2 wt% of glycerin, 3 wt% of propylene glycol, 0.5 wt% of trehalose, 0.2 wt% of xanthan gum, 1% by weight of a clay compound obtained by mixing kaolin and montmorillonite having a particle size of -2 탆 in a weight ratio of 1: 1, 3.5% by weight of glyceryl stearate as an emulsifier, 12% by weight of ester oil, citrus peel, 2% by weight of complex fermented extract, 0.5% by weight of preservative, 0.5% by weight of aroma oil, 0.5% by weight of pH adjusting agent 0.5% by weight of corn oil, 1: 1: 1: 1 by weight of a mixed microorganism, By weight, and the remaining purified water.
The method according to claim 1,
The purified water used as the solvent used in the dispersion step was prepared by mixing distilled water heated to 50-50 ° C with 50% by volume of filtered water obtained by filtering a mixture of tourmaline powder heated to 40-50 ° C and talc powder in a weight ratio of 2: 1; And 50 vol% of alkaline ion electrolytic reduced water obtained by electrolysis of tap water.
The method of claim 2,
Wherein the dispersing step is configured to agitate at 100-200 rpm for 10-15 minutes.