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KR102722990B1 - Nutrient composition for improving joint health in pet dogs containing boswllia extract - Google Patents

Nutrient composition for improving joint health in pet dogs containing boswllia extract Download PDF

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KR102722990B1
KR102722990B1 KR1020230067873A KR20230067873A KR102722990B1 KR 102722990 B1 KR102722990 B1 KR 102722990B1 KR 1020230067873 A KR1020230067873 A KR 1020230067873A KR 20230067873 A KR20230067873 A KR 20230067873A KR 102722990 B1 KR102722990 B1 KR 102722990B1
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한상민
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/20Animal feeding-stuffs from material of animal origin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/40Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S426/00Food or edible material: processes, compositions, and products
    • Y10S426/805Pet food for dog, cat, bird, or fish

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Birds (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Fodder In General (AREA)

Abstract

본 발명은 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물에 관한 것으로, 더욱 상세하게는 당성분 100 중량부, 보스웰리아 추출물 1 내지 3 중량부, 치즈 분말 5 내지 10 중량부, 글루코사민 3 내지 5 중량부, 프로폴리스 0.5 내지 1 중량부, 산화아연 0.5 내지 1 중량부, 비타민 D3 0.01 내지 0.1 중량부, 오르니틴 염산염 0.1 내지 0.5 중량부, 홍화씨 혼합물 3 내지 5 중량부, 관절개선용 한약재 1 내지 3 중량부, 천연 보존제 0.01 내지 0.1 중량부, 난소화성말토덱스트린 10 내지 15 중량부 및 결정 셀룰로오스 15 내지 20 중량부로 이루어진다.
상기의 성분으로 이루어지는 반려견 관절건강 개선용 영양제 조성물은 관절에 유익한 영양성분이 풍부하게 함유되어 반려견의 관절건강을 개선하며, 우수한 기호도와 보존성을 나타낸다.
The present invention relates to a nutritional composition for improving joint health in dogs containing a Boswellia extract, and more specifically, the nutritional composition comprises 100 parts by weight of a sugar component, 1 to 3 parts by weight of a Boswellia extract, 5 to 10 parts by weight of cheese powder, 3 to 5 parts by weight of glucosamine, 0.5 to 1 part by weight of propolis, 0.5 to 1 part by weight of zinc oxide, 0.01 to 0.1 part by weight of vitamin D3 , 0.1 to 0.5 part by weight of ornithine hydrochloride, 3 to 5 parts by weight of a safflower seed mixture, 1 to 3 parts by weight of a herbal medicine for improving joints, 0.01 to 0.1 parts by weight of a natural preservative, 10 to 15 parts by weight of resistant maltodextrin, and 15 to 20 parts by weight of crystalline cellulose.
The nutritional composition for improving joint health in dogs, consisting of the above ingredients, contains abundant nutrients beneficial to joints, improves joint health in dogs, and exhibits excellent palatability and storability.

Description

보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물 {NUTRIENT COMPOSITION FOR IMPROVING JOINT HEALTH IN PET DOGS CONTAINING BOSWLLIA EXTRACT}{NUTRIENT COMPOSITION FOR IMPROVING JOINT HEALTH IN PET DOGS CONTAINING BOSWLLIA EXTRACT}

본 발명은 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물에 관한 것으로, 더욱 상세하게는 관절에 유익한 영양성분이 풍부하게 함유되어 반려견의 관절건강을 개선하며, 우수한 기호도와 보존성을 나타내는 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물에 관한 것이다.The present invention relates to a nutritional composition for improving joint health in dogs containing a Boswellia extract, and more specifically, to a nutritional composition for improving joint health in dogs containing a Boswellia extract, which is rich in nutrients beneficial to joints and improves joint health in dogs, and exhibits excellent palatability and storability.

종래에는 사람과 같이 생활하는 개나 고양이 등의 동물을 사람에게 즐거움을 주기 위해 기르는 동물이라는 뜻으로 '애완동물'이라 칭하였으나, 최근에는 동물이 사람과 함께 더불어 살아가며 심리적으로 안정감과 친밀감을 주는 친구나 가족과 같은 존재라는 뜻에서 '반려동물'이라 부르고 있다.In the past, animals such as dogs and cats that live with people were called 'pets' to mean animals that are kept to provide enjoyment to people, but recently, they are called 'companion animals' to mean that animals are like friends or family members who live with people and provide psychological stability and intimacy.

반려동물은 전통적인 반려동물인 개와 고양이뿐만 아니라 앵무새, 고슴도치, 토끼 및 햄스터 등으로 그 종류가 다양해지고 있는데, 최근에는 반려동물에 대한 애정의 표현 정도가 높아지고, 반려동물을 보살피기 위한 관련 산업이 각광을 받고 있다.Pets are becoming more diverse, not only in the traditional pets like dogs and cats, but also in parrots, hedgehogs, rabbits, and hamsters. Recently, the level of affection shown toward pets has increased, and related industries for caring for pets are gaining attention.

이에 반려동물의 사료나 간식과 관련한 산업은 반려동물의 건강과 직결된 산업에 해당하기 때문에 더욱 관심이 집중되는 분야이고, 반려동물의 사료나 간식도 사람이 섭취하는 음식과 비슷한 종류의 것까지 접근해 있는 추세이며, 반려동물의 사료나 간식이 될 수 있는 비스켓, 껌, 육포 또는 음료 등은 반려동물의 건강에 유익할 뿐만 아니라 스트레스도 줄여줄 수 있기 때문에 사람의 음식과 더욱 유사한 종류로 확장되고 있다.Accordingly, the industry related to pet food and snacks is a field that is receiving more attention because it is directly related to the health of pets, and the trend is for pet food and snacks to approach the type similar to food consumed by humans. Biscuits, gum, jerky, and drinks that can be pet food or snacks are not only beneficial to the health of pets but can also reduce stress, so they are expanding into types that are more similar to human food.

또한, 최근에는 반려동물의 사료나 간식이 단순히 영양 성분을 공급하기 위한 수단에서 벗어나, 각종 기능성 성분을 함유하여, 반려동물의 건강을 증진시킬 뿐만 아니라 기호도에 맞게 식감이나 향 등이 개선된 제품에 대한 소비자의 요구가 증가하고 있다.In addition, recently, there has been an increase in consumer demand for products that go beyond simply providing nutrients for pet food and snacks to products that contain various functional ingredients to not only improve the health of pets but also have improved texture and flavor to suit their preferences.

또한, 반려동물에 관심의 증가와 의료서비스의 질이 향상되면서, 그에 따른 반려동물의 수명도 점차 향상되고 있고, 반려동물의 수명이 향상됨에 따라 관절질환을 앓는 반려동물의 수도 점차 증가하고 있으나, 이러한 문제점을 개선하기 위한 사료, 간식 및 영양제 등의 개발은 진행되지 못하고 있는 문제점이 있었다.In addition, as interest in companion animals increases and the quality of medical services improves, the life expectancy of companion animals is gradually increasing, and as the life expectancy of companion animals improves, the number of companion animals suffering from joint diseases is also gradually increasing. However, there has been a problem in that the development of feed, snacks, and nutritional supplements to improve these problems has not progressed.

한국특허등록 제10-2168587호(2020.10.15.)Korean Patent Registration No. 10-2168587 (October 15, 2020) 한국특허등록 제10-2287247호(2021.08.02.)Korean Patent Registration No. 10-2287247 (2021.08.02.)

본 발명의 목적은 관절에 유익한 영양성분이 풍부하게 함유되어 반려견의 관절건강을 개선하며, 우수한 기호도와 보존성을 나타내는 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제공하는 것이다.The purpose of the present invention is to provide a nutritional composition for improving joint health in dogs, which contains abundant nutrients beneficial to joints, improves joint health in dogs, and contains a boswellia extract exhibiting excellent palatability and storability.

본 발명의 목적은 당성분 100 중량부, 보스웰리아 추출물 1 내지 3 중량부, 치즈 분말 5 내지 10 중량부, 글루코사민 3 내지 5 중량부, 프로폴리스 0.5 내지 1 중량부, 산화아연 0.5 내지 1 중량부, 비타민 D3 0.01 내지 0.1 중량부, 오르니틴 염산염 0.1 내지 0.5 중량부, 홍화씨 혼합물 3 내지 5 중량부, 관절개선용 한약재 1 내지 3 중량부, 천연 보존제 0.01 내지 0.1 중량부, 난소화성말토덱스트린 10 내지 15 중량부 및 결정 셀룰로오스 15 내지 20 중량부로 이루어지며, 상기 보스웰리아 추출물은 보스웰리아 100 중량부에 질량농도가 80 내지 90%인 에탄올 500 내지 1000 중량부를 혼합하고 65 내지 75℃의 온도에서 5 내지 7시간 동안 2 내지 4회 반복추출한 후에, 여과 및 진공농축하여 제조되는 것을 특징으로 하는 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제공함에 의해 달성된다.The purpose of the present invention is to provide a composition comprising 100 parts by weight of a sugar component, 1 to 3 parts by weight of a Boswellia extract, 5 to 10 parts by weight of cheese powder, 3 to 5 parts by weight of glucosamine, 0.5 to 1 part by weight of propolis, 0.5 to 1 part by weight of zinc oxide, 0.01 to 0.1 parts by weight of vitamin D3 , 0.1 to 0.5 parts by weight of ornithine hydrochloride, 3 to 5 parts by weight of a safflower seed mixture, 1 to 3 parts by weight of a herbal medicine for improving joints, 0.01 to 0.1 parts by weight of a natural preservative, 10 to 15 parts by weight of indigestible maltodextrin, and 15 to 20 parts by weight of crystalline cellulose, wherein the Boswellia extract is prepared by mixing 100 parts by weight of Boswellia with 500 to 1,000 parts by weight of ethanol having a mass concentration of 80 to 90% and mixing the mixture at a temperature of 65 to 75°C for 5 to 10 minutes. This is achieved by providing a nutritional composition for improving joint health in companion dogs containing a Boswellia extract, characterized in that it is manufactured by repeated extraction 2 to 4 times over 7 hours, followed by filtration and vacuum concentration.

본 발명의 바람직한 특징에 따르면, 상기 홍화씨 혼합물은 홍화씨 100 중량부, 미역귀 30 내지 50 중량부 및 난각 10 내지 30 중량부로 이루어지는 것으로 한다.According to a preferred feature of the present invention, the safflower seed mixture is composed of 100 parts by weight of safflower seeds, 30 to 50 parts by weight of seaweed, and 10 to 30 parts by weight of eggshell.

본 발명의 더 바람직한 특징에 따르면, 상기 한약재는 황칠, 우슬, 마가목 및 헛개로 이루어진 그룹에서 선택된 하나 이상으로 이루어지는 것으로 한다.According to a more preferred feature of the present invention, the herbal medicine is composed of at least one selected from the group consisting of Phellodendron amurense, Usul, Maga tree, and Houttuynia cordata.

본 발명의 더욱 바람직한 특징에 따르면, 상기 천연보존제는 녹차, 머스타드, 로즈마리 및 세이지로 이루어진 그룹에서 선택된 하나의 동결건조 분말인 것으로 한다.According to a further preferred feature of the present invention, the natural preservative is a freeze-dried powder selected from the group consisting of green tea, mustard, rosemary and sage.

본 발명의 더욱 더 바람직한 특징에 따르면, 상기 당성분은 무수결정포도당, 프락토올리고당, 이소말토올리고당, 갈락토올리고당, 말토올리고당, 자일로올리고당 및 겐티오올리고당으로 이루어진 그룹에서 선택된 하나 이상으로 이루어지는 것으로 한다.According to a further preferred feature of the present invention, the sugar component is composed of at least one selected from the group consisting of anhydrous glucose, fructooligosaccharide, isomaltooligosaccharide, galactooligosaccharide, maltooligosaccharide, xylooligosaccharide and gentiooligosaccharide.

본 발명에 따른 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물은 관절에 유익한 영양성분이 풍부하게 함유되어 반려견의 관절건강을 개선하며, 우수한 기호도와 보존성을 나타내는 영양제 조성물을 제공하는 탁월한 효과를 나타낸다.The nutritional composition for improving joint health in dogs containing a Boswellia extract according to the present invention is rich in nutrients beneficial to joints, and exhibits excellent effects by providing a nutritional composition that improves joint health in dogs and exhibits excellent palatability and storability.

이하에는, 본 발명의 바람직한 실시예와 각 성분의 물성을 상세하게 설명하되, 이는 본 발명이 속하는 기술분야에서 통상의 지식을 가진 자가 발명을 용이하게 실시할 수 있을 정도로 상세하게 설명하기 위한 것이지, 이로 인해 본 발명의 기술적인 사상 및 범주가 한정되는 것을 의미하지는 않는다.Hereinafter, preferred embodiments of the present invention and the properties of each component will be described in detail. However, this is intended to be a detailed description to enable a person having ordinary skill in the art to which the present invention pertains to easily carry out the invention, and does not mean that the technical idea and scope of the present invention are limited thereby.

본 발명에 따른 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물은 당성분, 보스웰리아 추출물, 치즈 분말, 글루코사민, 프로폴리스, 산화아연, 비타민 D3, 오르니틴 염산염, 홍화씨 혼합물, 관절개선용 한약재, 천연 보존제, 난소화성말토덱스트린 및 결정 셀룰로오스로 이루어지며, 당성분 100 중량부, 보스웰리아 추출물 1 내지 3 중량부, 치즈 분말 5 내지 10 중량부, 글루코사민 3 내지 5 중량부, 프로폴리스 0.5 내지 1 중량부, 산화아연 0.5 내지 1 중량부, 비타민 D3 0.01 내지 0.1 중량부, 오르니틴 염산염 0.1 내지 0.5 중량부, 홍화씨 혼합물 3 내지 5 중량부, 관절개선용 한약재 1 내지 3 중량부, 천연 보존제 0.01 내지 0.1 중량부, 난소화성말토덱스트린 10 내지 15 중량부 및 결정 셀룰로오스 15 내지 20 중량부로 이루어지는 것이 바람직하다.The nutritional composition for improving joint health of companion dogs containing a Boswellia extract according to the present invention comprises a sugar component, a Boswellia extract, cheese powder, glucosamine, propolis, zinc oxide, vitamin D3, ornithine hydrochloride, a safflower seed mixture, a herbal medicine for improving joints, a natural preservative, indigestible maltodextrin, and crystalline cellulose, and comprises 100 parts by weight of a sugar component, 1 to 3 parts by weight of a Boswellia extract, 5 to 10 parts by weight of a cheese powder, 3 to 5 parts by weight of glucosamine, 0.5 to 1 part by weight of propolis, 0.5 to 1 part by weight of zinc oxide, 0.01 to 0.1 parts by weight of vitamin D3 , 0.1 to 0.5 parts by weight of ornithine hydrochloride, 3 to 5 parts by weight of a safflower seed mixture, 1 to 3 parts by weight of a herbal medicine for improving joints, 0.01 to 0.1 parts by weight of a natural preservative, It is preferably composed of 10 to 15 parts by weight of indigestible maltodextrin and 15 to 20 parts by weight of crystalline cellulose.

상기 당성분은 본 발명에 따른 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물에 단맛을 부여하여 기호도를 향상 시키는 역할을 하는데, 무수결정포도당, 프락토올리고당, 이소말토올리고당, 갈락토올리고당, 말토올리고당, 자일로올리고당, 겐티오올리고당 및 아가베시럽으로 이루어진 그룹에서 선택된 하나 이상으로 이루어지는 것이 바람직하며, 무수결정포도당 100 중량부에 프락토올리고당, 이소말토올리고당, 갈락토올리고당, 말토올리고당, 자일로올리고당 및 겐티오올리고당으로 이루어진 그룹에서 선택된 하나 이상의 올리고당 5 내지 10 중량부를 혼합하여 이루어지는 것이 더욱 바람직하다.The above-mentioned sugar component serves to improve palatability by providing a sweet taste to the nutritional composition for improving joint health of companion dogs containing the Boswellia extract according to the present invention, and is preferably composed of at least one selected from the group consisting of anhydrous crystalline glucose, fructooligosaccharide, isomaltooligosaccharide, galactooligosaccharide, maltooligosaccharide, xylooligosaccharide, gentioligosaccharide, and agave syrup, and is more preferably composed by mixing 5 to 10 parts by weight of at least one oligosaccharide selected from the group consisting of fructooligosaccharide, isomaltooligosaccharide, galactooligosaccharide, maltooligosaccharide, xylooligosaccharide, and gentioligosaccharide with 100 parts by weight of anhydrous crystalline glucose.

상기 무수결정포도당은 단맛을 부가할 뿐만 아니라, 본 발명에 따른 영양제 조성물을 분말형태로의 제조하는 과정에서 분말화 공정의 효율성을 증진시키는 역할을 하며, 상기 프락토올리고당, 이소말토올리고당, 갈락토올리고당, 말토올리고당, 자일로올리고당 및 겐티오올리고당은 단맛을 부여하면서도 체내 흡수율이 낮은 성분으로 이루어져 반려 동물의 건강을 증진시키는 역할을 한다.The above anhydrous crystalline glucose not only adds sweetness, but also plays a role in improving the efficiency of the powdering process in the process of manufacturing the nutritional composition according to the present invention in powder form, and the fructooligosaccharide, isomaltooligosaccharide, galactooligosaccharide, maltooligosaccharide, xylooligosaccharide, and gentiooligosaccharide are composed of components that provide sweetness but have a low absorption rate in the body, and thus play a role in improving the health of companion animals.

상기 무수결정포도당 100 중량부 대비 올리고당의 함량이 5 중량부 미만이면 영양제 조성물의 단맛과 기호도가 저하될 수 있으며, 올리고당의 함량이 10 중량부를 초과하게 되면 영양제 조성물의 분말화 공정의 효율성이 저하될 수 있다.If the content of oligosaccharide is less than 5 parts by weight based on 100 parts by weight of the anhydrous crystalline glucose, the sweetness and palatability of the nutritional composition may be reduced, and if the content of oligosaccharide exceeds 10 parts by weight, the efficiency of the powdering process of the nutritional composition may be reduced.

상기 보스웰리아(Boswellia) 추출물은 1 내지 3 중량부가 함유되며, 보스웰리아 100 중량부에 질량농도가 80 내지 90%인 에탄올 500 내지 1000 중량부를 혼합하고 65 내지 75℃의 온도에서 5 내지 7시간 동안 2 내지 4회 반복추출한 후에, 여과 및 진공농축하여 제조되는 것이 바람직한데, 본 발명을 통해 제조되는 반려견 관절건강 개선용 영양제 조성물에 관절염 증상 완화, 면역력 증진, 항염 및 항암, 상처 치유, 근육 강화, 두통 예방 및 피부 건강 증진 등의 효과를 부여하는 역할을 한다.The above Boswellia extract is contained in an amount of 1 to 3 parts by weight, and is preferably manufactured by mixing 500 to 1,000 parts by weight of ethanol having a mass concentration of 80 to 90% with 100 parts by weight of Boswellia, repeatedly extracting the mixture 2 to 4 times for 5 to 7 hours at a temperature of 65 to 75°C, and then filtering and concentrating under vacuum. The nutritional composition for improving joint health in dogs manufactured through the present invention has the effects of alleviating arthritis symptoms, enhancing immunity, anti-inflammation and anti-cancer, wound healing, muscle strengthening, headache prevention, and skin health promotion.

보스웰리아(Boswellia)는 유향나무의 유향을 일컬으며, 유향의 수지를 가공해 얻어지는 보스웰리아 추출물에는 β-보스웰산(β-boswellic acid), AKBA, 테르페노이드(terpenoid) 등이 함유되어 있는데, 이 중 β-보스웰산은 연골세포 괴사방지, 연골세포 증식촉진, 항염증 반응 등에 관련되어 있어 반려견의 관절 건강 증진 효과를 나타낸다.Boswellia refers to the frankincense of the frankincense tree, and the boswellia extract obtained by processing the resin of the frankincense tree contains β-boswellic acid, AKBA, and terpenoids. Among these, β-boswellic acid is related to preventing cartilage cell necrosis, promoting cartilage cell proliferation, and anti-inflammatory reactions, and thus shows the effect of promoting joint health in companion dogs.

상기의 과정으로 진행되는 보스웰리아 추출물의 제조과정은 상기 β-보스웰산이 다량 함유되어 있는 상기 보스웰리아 추출물을 제공하여 반려견의 관절 건강 증진 효과가 우수한 보스웰리아 추물을 제공하게 되는데, 상기 보스웰리아 추출물의 함량이 1 중량부 미만이면 상기의 효과가 미미하며, 상기 보스웰리아 추출물의 함량이 3 중량부를 초과하게 되면 상기의 효과는 크게 향상되지 않으면서 영양제 조성물의 기호도를 저하시키고 제조비용을 지나치게 증가시키기 때문에 바람직하지 못하다.The manufacturing process of the Boswellia extract carried out through the above process provides the Boswellia extract containing a large amount of the β-boswellic acid, thereby providing a Boswellia extract having an excellent effect of promoting joint health in companion dogs. However, if the content of the Boswellia extract is less than 1 part by weight, the effect is minimal, and if the content of the Boswellia extract exceeds 3 parts by weight, the effect is not significantly improved, while lowering the palatability of the nutritional composition and excessively increasing the manufacturing cost, which is not preferable.

상기 치즈 분말은 5 내지 10 중량부가 함유되며, 고소한 맛과 칼슘과 같은 다양한 영양성분이 풍부하게 함유되어 기호도가 우수하면서도 영양성분이 풍부하게 함유되어 있으며, 반려견의 관절 건강 개선효과를 나타내는 영양제 조성물을 제공하는 역할을 한다.The cheese powder is contained in an amount of 5 to 10 parts by weight, and is rich in various nutrients such as calcium and has excellent palatability while being rich in nutrients, and serves to provide a nutritional composition that shows the effect of improving the joint health of companion dogs.

상기 치즈 분말의 함량이 5 중량부 미만이면 상기의 효과가 미미하며, 상기 치즈 분말의 함량이 10 중량부를 초과하게 되면 상기의 효과는 크게 향상되지 않으면서 제조비용을 지나치게 증가시키기 때문에 바람직하지 못하다.If the content of the above cheese powder is less than 5 parts by weight, the above effect is minimal, and if the content of the above cheese powder exceeds 10 parts by weight, the above effect is not significantly improved, but the manufacturing cost increases excessively, which is not preferable.

상기 글루코사민은 3 내지 5 중량부가 함유되며, 본 발명을 통해 제조되는 반려견 관절건강 개선용 영양제 조성물에 관절 건강 개선 효과를 부여하는 역할을 하는데, 더욱 상세하게 설명하면 글루코사민은 체내에서 발견되는 천연물질로서, 생체중의 여러 가지 복합 당질의 당쇄중에 구성단위로 존재하는데, 대표적인 것으로는 콘드로이친황산이나 히아론산의 뮤코다당류를 포함하는 프로테오글리칸이며, 종합조직, 피부조직, 연골 및 관절액 등에 많이 분포되어 있다.The above glucosamine is contained in an amount of 3 to 5 parts by weight, and plays a role in providing a joint health improvement effect to the nutritional composition for improving joint health in companion dogs manufactured through the present invention. To explain in more detail, glucosamine is a natural substance found in the body, and exists as a structural unit in the sugar chains of various complex carbohydrates in the body. Representative examples include proteoglycans including mucopolysaccharides such as chondroitin sulfate or hyaluronic acid, and are widely distributed in general tissues, skin tissues, cartilage, and synovial fluid.

이러한 글루코사민은 높은 보습효과를 가지고 세포의 기능이나 형태를 유지하며 윤활작용, 세포접착, 증식 및 분화 등의 세포표면에 있어서 중요한 기능을 담당하기 때문에, 반려견의 관절 건강을 개선하는 역할을 하게 된다.These glucosamines have a high moisturizing effect, maintain cell function and shape, and play important roles in cell surface functions such as lubrication, cell adhesion, proliferation, and differentiation, so they play a role in improving the joint health of companion dogs.

상기 글루코사민의 함량이 3 중량부 미만이면 관절 건강 개선 효과가 미미하며, 상기 글루코사민의 함량이 5 중량부를 초과하게 되면 상기의 효과는 크게 향상되지 않으면서 영양제 조성물의 제조비용을 지나치게 증가시키게 된다.If the content of the above glucosamine is less than 3 parts by weight, the effect of improving joint health is minimal, and if the content of the above glucosamine exceeds 5 parts by weight, the effect is not significantly improved, while the manufacturing cost of the nutritional composition excessively increases.

상기 프로폴리스는 0.5 내지 1 중량부가 함유되며, 분말형태로 적용되는 것이 바람직하고 반려견의 관절염을 개선하는 역할을 하는데, 더욱 상세하게 설명하면 프로필로스는 꿀벌이 자신의 생존과 번식을 위해 여러 식물에서 뽑아낸 수지와 같은 물질에 자신의 침과 효소 등을 섞어서 만든 물질로 유기물과 미네랄(무기염류)이 다량 함유되어 있는데, 미네랄, 비타민, 아미노산, 지방, 유기산 및 플라보노이드(flavonoid)는 세포대사에 중요한 역할을 하며, 전체적으로 항염, 항산화 및 항균 에 효과를 나타낸다.The above propolis is contained in an amount of 0.5 to 1 part by weight, and it is preferable to apply it in powder form, and it plays a role in improving arthritis in companion dogs. To explain in more detail, propylose is a substance made by bees by mixing their saliva and enzymes with resin-like substances extracted from various plants for their survival and reproduction, and contains a large amount of organic matter and minerals (inorganic salts). Minerals, vitamins, amino acids, fats, organic acids, and flavonoids play an important role in cell metabolism, and overall, it exhibits anti-inflammation, antioxidant, and antibacterial effects.

상기 프로폴리스 분말의 함량이 0.5 중량부 미만이면 상기의 효과가 미미하며, 상기 프로폴리스 분말의 함량이 1 중량부를 초과하게 되면 상기의 효과는 크게 향상되지 않으면서 제조비용을 지나치게 증가시키게 된다.If the content of the above propolis powder is less than 0.5 parts by weight, the above effect is minimal, and if the content of the above propolis powder exceeds 1 part by weight, the above effect is not significantly improved, while the manufacturing cost increases excessively.

상기 산화아연은 0.5 내지 1 중량부가 함유되며, 산소와 아연의 화합물로 가벼운 백색 분말이며 아연화, 아연백이라고도 하는데, 천연에서는 홍아연석으로 존재하며 연소 및 가열 등을 통해 제조되는데, 본 발명을 통해 제조되는 반려견 관절건강 개선용 영양제 조성물에 관절 건강 개선 및 면역력 향상 효과를 부여하는 역할을 한다.The above zinc oxide is contained in an amount of 0.5 to 1 part by weight, and is a light white powder made of a compound of oxygen and zinc, also called zincite or zinc white. It exists in nature as red zinc stone and is manufactured through combustion and heating, etc., and plays a role in providing joint health improvement and immunity enhancement effects to the nutritional composition for improving joint health in dogs manufactured through the present invention.

상기 비타민 D3는 0.01 내지 0.1 중량부가 함유되며, 칼슘의 정상적인 흡수를 돕기 때문에, 반려견 뼈의 올바른 형성을 촉진하여 관절을 튼튼하게하는 역할을 한다.The above vitamin D3 is contained in 0.01 to 0.1 parts by weight, and helps the normal absorption of calcium, thereby promoting the proper formation of the dog's bones and strengthening the joints.

최근 반려견은 대부분의 시간을 실내에서 보내기 때문에, 햇빛에 노출되는 시간이 적어 반료견의 체내에서 비타민 D3가 합성되는 비율이 낮기 때문에, 비타민 D3를 섭취하게 되면 반려견의 골밀도를 향상시키는 효과가 나타나게 된다.These days, since companion dogs spend most of their time indoors, their exposure to sunlight is limited, and the rate at which vitamin D3 is synthesized in their bodies is low. Therefore, consuming vitamin D3 has the effect of improving bone density in companion dogs.

상기 오르니틴 염산염은 0.1 내지 0.5 중량부가 함유되며, 향미 증진제의 역할을 할 뿐만 아니라, 성장호르몬을 분비해 근육 합성을 촉진하고 기초대사를 향상시켜 반려견의 관절건강과 비만을 개선하며, 간장장애를 개선하는 효과를 나타내는데, L-오르니틴이나 L-아스파트산염 형태를 나타내는 것을 사용하는 것이 바람직하다.The above ornithine hydrochloride is contained in an amount of 0.1 to 0.5 parts by weight, and not only acts as a flavor enhancer, but also secretes growth hormones to promote muscle synthesis and improve basal metabolism, thereby improving joint health and obesity in companion dogs and improving liver disorders. It is preferable to use one in the form of L-ornithine or L-aspartate.

상기 홍화씨 혼합물은 3 내지 5 중량부가 함유되며, 홍화씨에 함유된 금속 이온 중 백금 성분은 전기적 작용을 유발하여 골절 시 조골모유사세포의 증식과 분The above safflower seed mixture contains 3 to 5 parts by weight, and the platinum component among the metal ions contained in the safflower seed induces an electrical action, thereby promoting the proliferation and division of osteoblast-like cells when fractured.

화를 활성화시켜 골 재생을 촉진하며, 홍화씨에 함유된 구리 성분은 칼슘을 다양한 골 세포와 서로 연결시키는 작용을 통해 반려견의 골 형성 및 재생을 촉진시켜 관절 건강을 유지하는데 도움을 준다.It activates calcium and promotes bone regeneration, and the copper contained in safflower seeds helps maintain joint health by promoting bone formation and regeneration in dogs through the action of linking calcium with various bone cells.

이때, 상기 홍화씨 혼합물은 홍화씨 100 중량부, 미역귀 30 내지 50 중량부 및 난각 10 내지 30 중량부로 이루어지는 것이 바람직하다.At this time, it is preferable that the safflower seed mixture is composed of 100 parts by weight of safflower seeds, 30 to 50 parts by weight of seaweed, and 10 to 30 parts by weight of eggshell.

상기 미역귀는 후코이단과 오메가-3 지방산이 다량 함유되어 있는데, 상기 후코이단은 관절염을 비롯한 염증성 질환을 개선하며, 상기 오메가-3 지방산은 관절염을 유발하는 염증의 정도를 줄여 반려견의 관절 건강을 향상시키는 역할을 한다.The above seaweed contains a large amount of fucoidan and omega-3 fatty acids. The fucoidan improves inflammatory diseases including arthritis, and the omega-3 fatty acids reduce the degree of inflammation that causes arthritis, thereby improving the joint health of companion dogs.

또한, 상기 난각은 알의 가장 바깥쪽에 위치한 단단한 막으로, 글리코사미노글리칸(glycosaminoglycans)이 다량 함유되어 있는데, 관절염에서 연골 회전율의 상태를 확인하는 혈청 CTX- II(C-telopeptide fragments of type II collagen) 수치를 개선시키는 것으로 조사되었다. CTX- II 수치의 개선은 유의미한 연골 보호 효과를 시사하므로, 난각이 연골 보호 효과를 가진다고 할 수 있다. 더욱이, 난각은 칼슘이 풍부하여 칼슘 보충제의 주 재료로 사용되고 있다. 따라서 난각은 반려견의 관절 건강을 유지시키는 효과를 나타낸다.In addition, the eggshell is a hard membrane located at the outermost part of the egg and contains a large amount of glycosaminoglycans, and it has been investigated to improve the serum CTX-II (C-telopeptide fragments of type II collagen) level, which determines the status of cartilage turnover in arthritis. Since the improvement in the CTX-II level suggests a significant cartilage protective effect, it can be said that the eggshell has a cartilage protective effect. Furthermore, the eggshell is rich in calcium and is used as the main ingredient in calcium supplements. Therefore, the eggshell shows the effect of maintaining the joint health of companion dogs.

상기의 성분으로 이루어지는 홍화씨 혼합물의 함량이 3 중량부 미만이면 상기의 효과가 미미하며, 상기 홍화씨 혼합물의 함량이 5 중량부를 초과하게 되면 상기의 효과는 크게 향상되지 않으면서 제조되는 반려견 관절건강 개선용 영양제 조성물의 기호도가 지나치게 저하될 수 있기 때문에 바람직하지 못하다.If the content of the safflower seed mixture comprising the above ingredients is less than 3 parts by weight, the above effect is minimal, and if the content of the safflower seed mixture exceeds 5 parts by weight, the above effect is not significantly improved, and the palatability of the nutritional composition for improving joint health in companion dogs may be excessively reduced, which is not preferable.

상기 관절개선용 한약재는 1 내지 3 중량부가 함유되며, 황칠, 우슬, 마가목 및 헛개로 이루어진 그룹에서 선택된 하나 이상으로 이루어지는 것이 바람직한데, 황칠, 우슬, 마가목 및 헛개가 1:1:1:1의 중량부로 이루어지는 것이 더욱 바람직하며, 상기의 성분으로 이루어지는 관절개선용 한약재는 반려견의 관절건강을 개선하는 효과를 나타낸다.The above herbal medicine for improving joints contains 1 to 3 parts by weight, and is preferably composed of at least one selected from the group consisting of Phellodendron amurense, Usul, Maga tree, and Heutgae. It is more preferable that the herbal medicine for improving joints consists of Phellodendron amurense, Usul, Maga tree, and Heutgae in a weight ratio of 1:1:1:1. The herbal medicine for improving joints composed of the above ingredients exhibits the effect of improving the joint health of companion dogs.

상기 황칠은 뼈 세포를 활성화하며 재생을 촉진하기 때문에 골다공증이나 관절염과 같은 질환을 개선하며, 어린 반려견의 뼈 골격 및 성발발육을 촉진하는 효과를 나타낸다. 또한, 상기 우슬은 우수한 항염 작용을 통해 관절염을 개선하여 반려견의 관절건강을 개선하는 효과를 나타낸다. 또한, 상기 마가목은 퇴행성 관절염이나 류마티스 관절염 등으로 인해 발생하는 관절 통증에 효과적이고, 상기 헛개는 우수한 항염효과를 나타내어 반려견의 관절염을 개선하는 효과를 나타낸다.The above-mentioned Hwangchil improves diseases such as osteoporosis and arthritis by activating bone cells and promoting regeneration, and has the effect of promoting bone skeleton and growth and development in young companion dogs. In addition, the above-mentioned Usul has the effect of improving arthritis through excellent anti-inflammatory action, thereby improving the joint health of companion dogs. In addition, the above-mentioned Ma-ga-mok is effective for joint pain caused by degenerative arthritis or rheumatoid arthritis, and the above-mentioned Heot-gae has an excellent anti-inflammatory effect and has the effect of improving arthritis in companion dogs.

상기 관절개선용 한약재의 함량이 1 중량부 미만이면 상기의 효과가 미미하며, 상기 관절개선용 한약재의 함량이 3 중량부를 초과하게 되면 상기의 효과는 크게 향상되지 않으면서 제조되는 반려견 관절건강 개선용 영양제 조성물의 기호도가 현저하게 저하되기 때문에 바람직하지 못하다.If the content of the above herbal medicine for improving joints is less than 1 part by weight, the above effect is minimal, and if the content of the above herbal medicine for improving joints exceeds 3 parts by weight, the above effect is not significantly improved, but the palatability of the nutritional composition for improving joint health in companion dogs is significantly reduced, which is not preferable.

상기 천연 보존제는 0.01 내지 0.1 중량부가 함유되며, 녹차 분말, 머스타드 분말, 로즈마리 분말 및 세이지 분말로 이루어진 그룹에서 선택된 하나로 이루어지는 것이 바람직하며, 녹차 분말, 머스타드 분말, 로즈마리 분말 및 세이지 분말이 1:1:1:1의 중량부로 혼합되어 이루어지는 것이 더욱 바람직하다.The above natural preservative is contained in an amount of 0.01 to 0.1 parts by weight, and is preferably composed of one selected from the group consisting of green tea powder, mustard powder, rosemary powder, and sage powder, and is more preferably composed of green tea powder, mustard powder, rosemary powder, and sage powder mixed in a weight ratio of 1:1:1:1.

상기와 같이 성분으로 이루어지는 천연보존제는 강력한 항산화, 항균 및 보존력을 나타내어 본 발명을 통해 제조되는 영양제 조성물에 항산화 효과를 부여할 뿐만 아니라, 영양제 조성물의 변질이나 세균의 증식을 억제하여 보존성을 월등하게 향상시키는 역할을 한다.As described above, the natural preservative composed of the ingredients exhibits strong antioxidant, antibacterial and preservative properties, and thus not only provides an antioxidant effect to the nutritional composition manufactured through the present invention, but also plays a role in significantly improving the preservability by inhibiting deterioration or bacterial growth of the nutritional composition.

상기 천연보존제의 함량이 0.01 중량부 미만이면 상기의 효과가 미미하며, 상기 천연보존제의 함량이 0.1 중량부를 초과하게 되면 상기의 효과는 크게 향상되지 않으면서 영양제 조성물의 기호도를 저하시키기 때문에 바람직하지 못하다.If the content of the above natural preservative is less than 0.01 part by weight, the above effect is minimal, and if the content of the above natural preservative exceeds 0.1 part by weight, the above effect is not significantly improved, but the palatability of the nutritional composition is lowered, which is not preferable.

상기 난소화성말토덱스트린은 10 내지 15 중량부가 함유되며, 본 발명을 통해 제조되는 반려견 관절건강 개선용 영양제 조성물에 혈당상승억제 효과를 부여하는 역할을 한다.The above-mentioned indigestible maltodextrin is contained in an amount of 10 to 15 parts by weight and has a role in providing a blood sugar level suppressing effect to the nutritional composition for improving joint health in companion dogs manufactured through the present invention.

본 발명을 통해 제조되는 반려견 관절건강 개선용 영양제 조성물은 당성분의 함량이 높기 때문에, 비교적 체내 흡수율이 낮은 무수결정포도당, 프락토올리고당, 이소말토올리고당, 갈락토올리고당, 말토올리고당, 자일로올리고당 및 겐티오올리고당 등으로 이루어진 당 성분을 사용한다고 하더라도 영양제 조성물을 섭취하는 반려견의 체내 혈당이 상승하게 되는데, 상기와 같이 난소화성말토덱스트린으로 이루어진 혈당상승억제제를 혼합하게 되면 반려견의 체내 혈당 상승을 억제할 수 있다.Since the nutritional composition for improving joint health in companion dogs manufactured through the present invention has a high sugar content, even if it uses sugar components such as anhydrous crystalline glucose, fructooligosaccharide, isomaltooligosaccharide, galactooligosaccharide, maltooligosaccharide, xytooligosaccharide, and gentiooligosaccharide, which have relatively low absorption rates in the body, the blood sugar level in the body of a companion dog consuming the nutritional composition increases. However, if a blood sugar increase suppressant composed of indigestible maltodextrin is mixed as described above, the increase in blood sugar level in the body of a companion dog can be suppressed.

또한, 상기 난소화성말토덱스트린은 수용성 식이섬유로, 혈당 상승 억제 효과 외에도, 장내 유익균 증가의 정장작용 및 혈중 지질 저하의 효과를 나타내어 반려견의 건강을 증진시키는 역할을 한다.In addition, the above-mentioned indigestible maltodextrin is a water-soluble dietary fiber that, in addition to the effect of suppressing blood sugar increase, has the effect of increasing intestinal beneficial bacteria and lowering blood lipids, thereby playing a role in promoting the health of companion dogs.

상기 난소화성말토덱스트린의 함량이 10 중량부 미만이면 상기의 효과가 미미하며, 상기 난소화성말토덱스트린의 함량이 15 중량부를 초과하게 되면 상기의 효과는 크게 향상되지 않으면서 영양제 조성물의 기호도가 지나치게 저하될 수 있기 때문에 바람직하지 못하다.If the content of the above-mentioned resistant maltodextrin is less than 10 parts by weight, the above-mentioned effect is minimal, and if the content of the above-mentioned resistant maltodextrin exceeds 15 parts by weight, the above-mentioned effect is not significantly improved, but the palatability of the nutritional composition may be excessively reduced, which is not preferable.

결정 셀룰로오스 15 내지 20 중량부가 함유되며, 발명을 통해 제조되는 영양제 조성물에 식이섬유 등을 공급할 뿐만 아니라, 고결방지효과를 나타내어 본 발명을 통해 제조되는 반려견 관절건강 개선용 영양제 조성물이 오랜 기간 동안 굳지 않고 분말형태를 유지할 수 있도록 하여 보존성을 향상시키는 역할을 한다.It contains 15 to 20 parts by weight of crystalline cellulose, and not only supplies dietary fiber, etc. to the nutritional composition manufactured through the invention, but also exhibits an anti-caking effect, thereby enabling the nutritional composition for improving joint health of companion dogs manufactured through the invention to maintain a powder form without hardening for a long period of time, thereby improving the preservation property.

상기 결정 셀룰로오스의 함량이 15 중량부 미만이면 영양제 조성물이 미량의 수분으로도 쉽게 뭉치는 현상이 발생할 수 있으며, 상기 결정 셀룰로오스의 함량이 20 중량부를 초과하게 되면 영양제 조성물의 고결방지효과는 크게 향상되지 않으면서 기호도가 지나치게 저하되기 때문에 바람직하지 못하다.If the content of the above-mentioned crystalline cellulose is less than 15 parts by weight, the nutritional composition may easily clump together even with a small amount of moisture, and if the content of the above-mentioned crystalline cellulose exceeds 20 parts by weight, the anti-caking effect of the nutritional composition is not significantly improved, but the palatability is excessively reduced, which is not preferable.

이하에서는, 본 발명에 따른 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물의 제조방법 및 그 제조방법으로 제조된 영양제 조성물의 물성을 실시예를 들어 설명하기로 한다.Hereinafter, a method for manufacturing a nutritional composition for improving joint health in dogs containing a Boswellia extract according to the present invention and the properties of a nutritional composition manufactured by the method will be described with reference to examples.

<제조예 1> 보스웰리아 추출물의 제조<Manufacturing Example 1> Manufacturing of Boswellia extract

보스웰리아 검레진 300g을 집기병에 담은 후 95% 에탄올 18ℓ를 혼합하고 70℃의 온도에서 6시간으로 3회 반복 추출한 후에, 추출물을 여과지(whatman No1, England)로 감압 여과한 후, 진공회전농축기를 이용하여 60℃의 온도에서 감압 농축하고 열풍 건조하여 분말 형태의 보스웰리아 추출물을 제조하였다.After placing 300 g of Boswellia gum resin in a spray bottle, mixing in 18 liters of 95% ethanol, extraction was repeated three times for 6 hours at a temperature of 70℃, and the extract was filtered under reduced pressure through a filter paper (Whatman No1, England), concentrated under reduced pressure at a temperature of 60℃ using a vacuum rotary evaporator, and dried with hot air to produce a Boswellia extract in powder form.

<제조예 2> 홍화씨 혼합물의 제조<Manufacturing Example 2> Manufacturing of safflower seed mixture

홍화씨 100 중량부, 미역귀 40 중량부 및 난각 20 중량부를 혼합하여 홍화씨 혼합물을 제조하였다.A safflower seed mixture was prepared by mixing 100 parts by weight of safflower seeds, 40 parts by weight of seaweed, and 20 parts by weight of egg shell.

<제조예 3> 관절개선용 한약재의 제조<Manufacturing Example 3> Manufacturing of herbal medicine for improving joints

황칠, 우슬, 마가목 및 헛개를 1:1:1:1의 중량부로 혼합하여 한약재 혼합물을 제조하였다.A mixture of herbal medicines was prepared by mixing Hwangchil, Usul, Maga tree, and Hutgae in a weight ratio of 1:1:1:1.

<제조예 4> 천연보존제의 제조<Manufacturing Example 4> Manufacturing of Natural Preservative

녹차 분말, 머스타드 분말, 로즈마리 분말 및 세이지 분말을 1:1:1:1의 중량부로 혼합하여 천연보존제를 제조하였다.A natural preservative was prepared by mixing green tea powder, mustard powder, rosemary powder, and sage powder in a weight ratio of 1:1:1:1.

<실시예 1><Example 1>

당성분(무수결정포도당) 100 중량부, 상기 제조예 1을 통해 제조된 보스웰리아 추출물 2 중량부, 치즈 분말 8 중량부, 글루코사민 4 중량부, 프로폴리스 0.8 중량부, 산화아연 0.8 중량부, 비타민 D3 0.05 중량부, 오르니틴 염산염 0.3 중량부, 상기 제조예 2를 통해 제조된 홍화씨 혼합물 4 중량부, 상기 제조예 3을 통해 제조된 관절개선용 한약재 2 중량부, 상기 제조예 4를 통해 제조된 천연 보존제 0.05 중량부, 난소화성말토덱스트린 12.5 중량부 및 결정 셀룰로오스 17.5 중량부를 교반기가 구비된 혼합장치에 투입하고 150rpm의 속도로 10분 동안 혼합하여 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.100 parts by weight of anhydrous glucose, 2 parts by weight of the Boswellia extract manufactured through the above Manufacturing Example 1, 8 parts by weight of cheese powder, 4 parts by weight of glucosamine, 0.8 parts by weight of propolis, 0.8 parts by weight of zinc oxide, 0.05 parts by weight of vitamin D 3 , 0.3 parts by weight of ornithine hydrochloride, 4 parts by weight of the safflower seed mixture manufactured through the above Manufacturing Example 2, 2 parts by weight of the herbal medicine for improving joints manufactured through the above Manufacturing Example 3, 0.05 parts by weight of the natural preservative manufactured through the above Manufacturing Example 4, 12.5 parts by weight of resistant maltodextrin, and 17.5 parts by weight of crystalline cellulose were placed into a mixing device equipped with a stirrer and mixed at a speed of 150 rpm for 10 minutes to manufacture a nutritional composition for improving joint health in companion dogs containing the Boswellia extract.

<실시예 2><Example 2>

상기 실시예 1과 동일하게 진행하되, 상기 제조예 1을 통해 제조된 보스웰리아 추출물 1 중량부, 상기 제조예 2를 통해 제조된 홍화씨 혼합물 3 중량부, 상기 제조예 3을 통해 제조된 관절개선용 한약재 1 중량부 및 상기 제조예 4를 통해 제조된 천연 보존제 0.01 중량부를 혼합하여 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.Proceed in the same manner as in Example 1, but mix 1 part by weight of the Boswellia extract manufactured through Manufacturing Example 1, 3 parts by weight of the safflower seed mixture manufactured through Manufacturing Example 2, 1 part by weight of the herbal medicine for improving joints manufactured through Manufacturing Example 3, and 0.01 part by weight of the natural preservative manufactured through Manufacturing Example 4 to manufacture a nutritional composition for improving joint health in companion dogs containing the Boswellia extract.

<실시예 3><Example 3>

상기 실시예 1과 동일하게 진행하되, 상기 제조예 1을 통해 제조된 보스웰리아 추출물 3 중량부, 상기 제조예 2를 통해 제조된 홍화씨 혼합물 5 중량부, 상기 제조예 3을 통해 제조된 관절개선용 한약재 3 중량부 및 상기 제조예 4를 통해 제조된 천연 보존제 0.1 중량부를 혼합하여 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.Proceed in the same manner as in Example 1, but mix 3 parts by weight of the Boswellia extract manufactured through Manufacturing Example 1, 5 parts by weight of the safflower seed mixture manufactured through Manufacturing Example 2, 3 parts by weight of the herbal medicine for improving joints manufactured through Manufacturing Example 3, and 0.1 part by weight of the natural preservative manufactured through Manufacturing Example 4 to manufacture a nutritional composition for improving joint health in companion dogs containing the Boswellia extract.

<실시예 4><Example 4>

상기 실시예 1과 동일하게 진행하되, 당성분(무수결정포도당 100 중량부 및 이소말토 올리고당 8 중량부가 혼합)을 사용하여 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.A nutritional composition for improving joint health in companion dogs containing a Boswellia extract was manufactured in the same manner as in Example 1, except that a sugar component (a mixture of 100 parts by weight of anhydrous crystalline glucose and 8 parts by weight of isomaltooligosaccharide) was used.

<실시예 5><Example 5>

상기 실시예 2와 동일하게 진행하되, 당성분(무수결정포도당 100 중량부 및 이소말토 올리고당 8 중량부가 혼합)을 사용하여 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.The same procedure as in Example 2 was followed, but a sugar component (100 parts by weight of anhydrous crystalline glucose and 8 parts by weight of isomaltooligosaccharide) was used to prepare a nutritional composition for improving joint health in companion dogs containing a Boswellia extract.

<실시예 6><Example 6>

상기 실시예 3과 동일하게 진행하되, 당성분(무수결정포도당 100 중량부 및 이소말토 올리고당 8 중량부가 혼합)을 사용하여 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.A nutritional composition for improving joint health in companion dogs containing a Boswellia extract was manufactured in the same manner as in Example 3 above, except that a sugar component (100 parts by weight of anhydrous crystalline glucose and 8 parts by weight of isomaltooligosaccharide mixed) was used.

<비교예 1><Comparative Example 1>

상기 실시예 1과 동일하게 진행하되, 상기 당성분을 사용하지 않고 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.A nutritional composition for improving joint health in companion dogs containing a Boswellia extract was manufactured in the same manner as in Example 1 above, but without using the sugar component.

<비교예 2><Comparative Example 2>

상기 실시예 1과 동일하게 진행하되, 상기 제조예 1을 통해 제조된 보스웰리아 추출물 5 중량부, 상기 제조예 2를 통해 제조된 홍화씨 혼합물 10 중량부, 상기 제조예 3을 통해 제조된 관절개선용 한약재 5 중량부 및 상기 제조예 4를 통해 제조된 천연 보존제 1 중량부를 혼합하여 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.Proceed in the same manner as in Example 1, except that 5 parts by weight of the Boswellia extract manufactured through Manufacturing Example 1, 10 parts by weight of the safflower seed mixture manufactured through Manufacturing Example 2, 5 parts by weight of the herbal medicine for improving joints manufactured through Manufacturing Example 3, and 1 part by weight of the natural preservative manufactured through Manufacturing Example 4 were mixed to manufacture a nutritional composition for improving joint health in companion dogs containing the Boswellia extract.

<비교예 3><Comparative Example 3>

상기 실시예 1과 동일하게 진행하되, 상기 천연 보존제를 사용하지 않고 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.A nutritional composition for improving joint health in companion dogs containing a Boswellia extract was manufactured in the same manner as in Example 1 above, but without using the natural preservative.

<비교예 4><Comparative Example 4>

상기 실시예 1과 동일하게 진행하되, 결정 셀룰로오스를 사용하지 않고 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.A nutritional composition for improving joint health in companion dogs containing a Boswellia extract was manufactured in the same manner as in Example 1 above, but without using crystalline cellulose.

<비교예 5><Comparative Example 5>

상기 실시예 1과 동일하게 진행하되, 결정 셀룰로오스 5g을 사용하여 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.The same procedure as in Example 1 was followed, but 5 g of crystalline cellulose was used to prepare a nutritional composition containing a Boswellia extract for improving joint health in companion dogs.

<비교예 6><Comparative Example 6>

상기 실시예 1과 동일하게 진행하되, 결정 셀룰로오스 50g을 사용하여 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물을 제조하였다.The same procedure as in Example 1 was followed, but 50 g of crystalline cellulose was used to manufacture a nutritional composition containing a Boswellia extract for improving joint health in companion dogs.

상기 실시예 1 내지 6 및 비교예 1 내지 6을 통해 제조된 반려견 관절건강 개선용 영양제 조성물의 기호도를 측정하여 아래 표 1에 나타내었다.The preference of the nutritional compositions for improving joint health in companion dogs manufactured through Examples 1 to 6 and Comparative Examples 1 to 6 was measured and shown in Table 1 below.

{단, 기호도는 견사육 시험장에서 급이기가 2개인 케이지에 개를 한 마리씩 배치하고, 매일 오전 10시부터 11시까지 1시간 동안 영양제 조성물 100g씩을 3일 동안 급여한 후에 용기에 남아있는 영양제의 잔량을 확인하여 평균값으로 나타내는 방법을 이용하였다. 이때, 상기 개는 체중이 3kg 내외인 소형견 5두를 사용하였다.}{However, the preference was measured by placing one dog in a cage with two feeders in a breeding test facility, feeding 100 g of nutritional composition every day for 1 hour from 10:00 to 11:00 for 3 days, and then checking the remaining nutritional composition in the container and expressing it as an average value. At this time, the dogs used were 5 small dogs weighing approximately 3 kg.}

<표 1><Table 1>

상기 표 1에 나타낸 것처럼, 본 발명의 실시예 1 내지 6를 통해 제조된 영양제 조성물은 비교예 1 내지 2 및 6을 통해 제조된 영양제 조성물에 비해 우수한 기호도를 나타내는 것을 알 수 있으며, 특히, 상기 실시예 1 내지 3에 비해서 당성분에 이소말토 올리고당이 더 함유된 실시예 4 내지 6을 통해 제조된 영양제 조성물의 기호도가 더욱 향상되는 것을 알 수 있다.As shown in Table 1 above, it can be seen that the nutritional compositions manufactured through Examples 1 to 6 of the present invention exhibit superior palatability compared to the nutritional compositions manufactured through Comparative Examples 1 to 2 and 6, and in particular, it can be seen that the palatability of the nutritional compositions manufactured through Examples 4 to 6, which contain more isomaltooligosaccharide in the sugar component, is further improved compared to Examples 1 to 3.

또한, 상기 실시예 1 내지 6 및 비교예 1 내지 6을 통해 제조된 반려견 관절건강 개선용 영양제 조성물의 제형안정성을 측정하여 아래 표 2에 나타내었다.In addition, the formulation stability of the nutritional compositions for improving joint health in companion dogs manufactured through Examples 1 to 6 and Comparative Examples 1 to 6 was measured and shown in Table 2 below.

{단, 제형안정성은 실시예 1 내지 6 및 비교예 1 내지 6을 통해 제조된 반려견 관절건강 개선용 영양제 조성물을 20℃의 온도와 상대습도 50%의 조건에서 72시간 동안 방치하여 고결여부를 육안과 지촉(指觸)으로 확인하는 방법을 이용하였다.{However, the stability of the formulation was checked by visually and tactilely checking whether the nutritional composition for improving joint health in dogs, manufactured through Examples 1 to 6 and Comparative Examples 1 to 6, was solidified for 72 hours under conditions of a temperature of 20°C and a relative humidity of 50%.

○:완전 고결, △:부분 고결, ×:고결 없음}○: Completely fixed, △: Partially fixed, ×: No fixed}

<표 2><Table 2>

상기 표 2에 나타낸 것처럼, 본 발명의 실시예 1 내지 6을 통해 제조된 영양제 조성물은 우수한 제형안정성을 나타내는 것을 알 수 있다.As shown in Table 2 above, it can be seen that the nutritional compositions manufactured through Examples 1 to 6 of the present invention exhibit excellent formulation stability.

반면, 비교예 4 내지 5를 통해 제조된 영양제 조성물은 고결방지 효과를 나타내는 결정 셀룰로오스가 함유되지 않거나 미량 함유되어 제형안정성이 낮은 것을 알 수 있다.On the other hand, it can be seen that the nutritional compositions manufactured through Comparative Examples 4 to 5 do not contain crystalline cellulose exhibiting an anti-caking effect or contain only a small amount, resulting in low formulation stability.

또한, 상기 실시예 1 내지 6 및 비교예 1 내지 6을 통해 제조된 반려견 관절건강 개선용 영양제 조성물의 항균성을 측정하여 아래 표 3에 나타내었다.In addition, the antibacterial activity of the nutritional compositions for improving joint health in dogs manufactured through Examples 1 to 6 and Comparative Examples 1 to 6 was measured and shown in Table 3 below.

{단, 항균성은 ASTM E2149-10에 의거하여 실시예 1 내지 6 및 비교예 1 내지 6을 통해 제조된 영양제 조성물의 시료를 10±0.1g 로 준비한 후, 각 시료별로 무균 250ml 진탕플라스크를 준비하여 세균 접종물의 실행 희석액 50±0.5ml를 각 플라스크에 추가하였다. 각 플라스크 속에 제조된 영양제 조성물의 시료를 각각 배치한 후, 각 플라스크들을 진탕기(wrist-action shaker) 위에 놓고 60±5분 동안 최대 속도로 흔들고 희석하여 평판 배지에 분주하고 24시간, 35±2℃ 인큐베이터에서 배양한 후 현미경으로 배양 페드리디쉬 내 집락수를 확인하는 방법을 이용하였다.{However, for antibacterial activity, 10±0.1 g of samples of the nutritional compositions manufactured through Examples 1 to 6 and Comparative Examples 1 to 6 were prepared according to ASTM E2149-10, and 50±0.5 ml of the running dilution of the bacterial inoculum was added to each flask. After placing a sample of the manufactured nutritional composition in each flask, each flask was placed on a wrist-action shaker and shaken at maximum speed for 60±5 minutes, and the diluted solution was dispensed onto a flat plate and cultured in an incubator at 35±2℃ for 24 hours, and the number of colonies in the cultured Pedri dishes was checked under a microscope.

또한, 하기 식에 의해 항균력을 계산하였다.Additionally, the antibacterial activity was calculated using the following formula.

항균력(%) = (B-A)/B × 100 Antibacterial power (%) = (B-A)/B × 100

A: 시료와 세균 희석액의 접촉시간 이후 세균수A: Bacterial count after contact time between sample and bacterial dilution solution

B: 시료를 처리하지 않은 대조군의 세균수B: Bacterial count in the untreated control group

* 음성대조군은 100%, 양성대조군 5.4%}* Negative control group 100%, positive control group 5.4%}

<표 3><Table 3>

상기 표 3에 나타낸 것처럼, 본 발명의 실시예 1 내지 6을 통해 제조된 영양제 조성물은 우수한 항균성능을 나타내었으나, 비교예 3과 같이 천연보존제가 함유되지 않은 영양제 조성물은 항균성능이 낮은 것을 알 수 있다.As shown in Table 3 above, the nutritional compositions manufactured through Examples 1 to 6 of the present invention exhibited excellent antibacterial performance, but it can be seen that the nutritional composition that did not contain a natural preservative, such as Comparative Example 3, had low antibacterial performance.

따라서, 본 발명에 따른 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물은 관절에 유익한 영양성분이 풍부하게 함유되어 반려견의 관절건강을 개선하며, 우수한 기호도와 보존성을 나타내는 영양제 조성물을 제공한다.Therefore, the nutritional composition for improving joint health in dogs containing a Boswellia extract according to the present invention contains an abundance of nutrients beneficial to joints, thereby improving joint health in dogs and providing a nutritional composition exhibiting excellent palatability and storability.

Claims (5)

당성분 100 중량부, 보스웰리아 추출물 1 내지 3 중량부, 치즈 분말 5 내지 10 중량부, 글루코사민 3 내지 5 중량부, 프로폴리스 0.5 내지 1 중량부, 산화아연 0.5 내지 1 중량부, 비타민 D3 0.01 내지 0.1 중량부, 오르니틴 염산염 0.1 내지 0.5 중량부, 홍화씨 혼합물 3 내지 5 중량부, 관절개선용 한약재 1 내지 3 중량부, 천연 보존제 0.01 내지 0.1 중량부, 난소화성말토덱스트린 10 내지 15 중량부 및 결정 셀룰로오스 15 내지 20 중량부로 이루어지며,
상기 보스웰리아 추출물은 보스웰리아 100 중량부에 질량농도가 80 내지 90%인 에탄올 500 내지 1000 중량부를 혼합하고 65 내지 75℃의 온도에서 5 내지 7시간 동안 2 내지 4회 반복추출한 후에, 여과 및 진공농축하여 제조되며,
상기 홍화씨 혼합물은 홍화씨 100 중량부, 미역귀 30 내지 50 중량부 및 난각 10 내지 30 중량부로 이루어지고,
상기 한약재는 황칠, 우슬, 마가목 및 헛개가 1:1:1:1의 중량부로 혼합되어이루어지며,
상기 천연보존제는 녹차, 머스타드, 로즈마리 및 세이지의 동결건조 분말이 1:1:1:1의 중량부로 혼합되어 이루어지는 것을 특징으로 하는 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물.
It consists of 100 parts by weight of a sugar component, 1 to 3 parts by weight of a boswellia extract, 5 to 10 parts by weight of cheese powder, 3 to 5 parts by weight of glucosamine, 0.5 to 1 part by weight of propolis, 0.5 to 1 part by weight of zinc oxide, 0.01 to 0.1 part by weight of vitamin D3 , 0.1 to 0.5 part by weight of ornithine hydrochloride, 3 to 5 parts by weight of a safflower seed mixture, 1 to 3 parts by weight of a herbal medicine for improving joints, 0.01 to 0.1 part by weight of a natural preservative, 10 to 15 parts by weight of indigestible maltodextrin, and 15 to 20 parts by weight of crystalline cellulose.
The above Boswellia extract is prepared by mixing 500 to 1,000 parts by weight of ethanol having a mass concentration of 80 to 90% with 100 parts by weight of Boswellia, repeatedly extracting the mixture 2 to 4 times for 5 to 7 hours at a temperature of 65 to 75°C, and then filtering and concentrating under vacuum.
The above safflower seed mixture is composed of 100 parts by weight of safflower seeds, 30 to 50 parts by weight of seaweed, and 10 to 30 parts by weight of eggshell.
The above herbal medicine is made up of a mixture of Phellodendron amurense, Usul, Maga tree, and Houttuynia cordata in a weight ratio of 1:1:1:1.
A nutritional composition for improving joint health in companion dogs containing a Boswellia extract, characterized in that the natural preservative is a mixture of freeze-dried powders of green tea, mustard, rosemary, and sage in a weight ratio of 1:1:1:1.
삭제delete 삭제delete 삭제delete 청구항 1에 있어서,
상기 당성분은 무수결정포도당, 프락토올리고당, 이소말토올리고당, 갈락토올리고당, 말토올리고당, 자일로올리고당 및 겐티오올리고당으로 이루어진 그룹에서 선택된 하나 이상으로 이루어지는 것을 특징으로 하는 보스웰리아 추출물이 함유된 반려견 관절건강 개선용 영양제 조성물.
In claim 1,
A nutritional composition for improving joint health in companion dogs containing a Boswellia extract, characterized in that the above-mentioned sugar component comprises at least one selected from the group consisting of anhydrous glucose, fructooligosaccharide, isomaltooligosaccharide, galactooligosaccharide, maltooligosaccharide, xytooligosaccharide, and gentiooligosaccharide.
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