KR102837801B1 - Manufacturing method of porous absorbent and porous absorbent manufactured therefrom - Google Patents

Abstract

The present specification relates to a method for manufacturing a porous absorbent and a porous absorbent manufactured therefrom. The method for manufacturing a porous absorbent and the porous absorbent manufactured therefrom according to one embodiment of the present invention prevent leakage of a liquid composition for an electronic cigarette and provide an environmentally friendly effect.

Description

Method for manufacturing porous absorbent and porous absorbent manufactured thereby {MANUFACTURING METHOD OF POROUS ABSORBENT AND POROUS ABSORBENT MANUFACTURED THEREFROM}

The present specification discloses a method for manufacturing a porous absorbent and a porous absorbent manufactured thereby.

Various types of aerosol generating devices are being developed to improve the side effects that may occur when smoking cigarettes. These aerosol generating devices are largely divided into types that generate aerosol by heating cigarettes wrapped in paper together with a filter by compressing tobacco leaves, and liquid types that generate aerosol by vaporizing a liquid filled in a liquid cartridge. Korean Patent Publication No. 10-2016-0119459 discloses an electronic cigarette liquid containing a natural concentrate as an active ingredient. However, there is a problem that the target ingredient may leak. In addition, there is a need for the development of a technology to apply moisture absorption of an electronic cigarette liquid composition that is directly inhaled into the human body to an environmentally friendly material that is harmless to the human body.

Korean Patent Publication No. 10-2016-0119459

An object of one aspect of the present invention is to provide a method for producing an environmentally friendly porous absorbent body and a porous absorbent body produced thereby, which prevents leakage of a liquid composition for an electronic cigarette.

In one aspect of the present invention, the present invention provides a method for manufacturing a porous absorbent, comprising the steps of: impregnating a porous absorbent with an eco-friendly powder aqueous solution or spraying an eco-friendly powder aqueous solution onto a porous absorbent to form a porous absorbent coated with eco-friendly powder; and drying the porous absorbent coated with the eco-friendly powder to form a porous absorbent coated with eco-friendly powder.

In another aspect, the present invention provides a porous absorbent manufactured by the above manufacturing method.

In another aspect, the present invention provides a cartridge for an electronic cigarette comprising the porous absorbent material.

In another aspect, the present invention provides an electronic cigarette comprising the cartridge for the electronic cigarette.

A method for manufacturing a porous absorbent according to one embodiment of the present invention and a porous absorbent manufactured thereby prevent leakage of a liquid composition for an electronic cigarette and provide an environmentally friendly effect.

FIG. 1 is a schematic diagram showing the structure of a cartridge for an electronic cigarette according to one embodiment of the present invention.
FIGS. 2a and 2b are photographs showing the appearance of a porous absorbent before and after coating according to one embodiment of the present invention.
FIG. 3a and FIG. 3b are photographs showing the liquid absorption pattern over time of a porous absorbent according to one embodiment of the present invention.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the attached drawings.

The embodiments of the present invention disclosed in the text are merely exemplified for the purpose of explanation, and the embodiments of the present invention may be implemented in various forms and should not be construed as limited to the embodiments described in the text. The present invention may have various modifications and may have various forms, and the embodiments are not intended to limit the present invention to a specific disclosed form, but should be understood to include all modifications, equivalents, or substitutes included in the spirit and technical scope of the present invention.

In this specification, when a part is said to “include” a component, this does not mean that it excludes other components, but rather that it may include other components, unless otherwise specifically stated.

Throughout the specification, similar parts are designated by the same reference numerals. Throughout the specification, when a layer, film, region, plate, etc., is referred to as being “on” or “over” another part, this includes not only cases where it is directly over the other part, but also cases where there are other parts in between. Throughout the specification, the terms first, second, etc. may be used to describe various components, but the components should not be limited by the terms. The terms are used only to distinguish one component from another.

Terminology

As used herein, “Nicotine” is an alkaloid molecule containing two basic nitrogens. Nicotine is a chemical stimulant and increases heart rate and blood pressure when administered to an individual or animal. Nicotine delivery to an individual is associated with physical and/or emotional gratification. Nicotine can occur in different states of protonation. For example, if no protonation is present, nicotine is referred to as “free-base nicotine.” If one nitrogen is protonated, nicotine will be “mono-” protonated, and if two nitrogens are protonated, nicotine will be “di-” protonated. The nicotine is naturally occurring nicotine (e.g., an extract of a nicotine species such as tobacco) or synthetic nicotine. The nicotine is (-)-nicotine, (+)-nicotine, or a mixture thereof. The nicotine is used in a relatively pure form (e.g., having a purity of greater than about 80%, 85%, 90%, 95%, or 99%). The nicotine is “colorless and transparent” in appearance to minimize or avoid the formation of tar residues.

As used herein, “free-base nicotine” refers to the unprotonated nicotine molecule. Also called nicotine or stem nicotine.

In this specification, the “Nicotine Salt” is formed by combining the basic molecule, free base nicotine, with an acid component, and as shown in the chemical formula 1 below, when nicotine and an acid component combine in an aqueous solution, the pH is lowered and the free base or unprotonated nicotine molecule changes into one of two protonation forms, such as monoprotonated and diprotonated.

[Chemical Formula 1]

The above monoprotonated nicotine salt is nonvolatile, exists in a liquid state in the aerosol droplets, is acidic (positively charged) when pK _a1 = 3.12 ≤ pH ≤ pK _a2 = 8.02, is slowly absorbed in the lungs, has a high inhalation concentration, low impact, and low unpleasant taste. Diprotonated nicotine salts such as nicotine salts using tartaric acid can also be used, and pK _a1 = pH ≥ 3.12. On the other hand, the free base nicotine is volatile, reverts to a gaseous state in the aerosol droplets, is neutral (uncharged) when pH > pK _a2 = 8.02, is rapidly absorbed in the oral cavity and the upper part of the trachea, has a low inhalation concentration, high impact, and high unpleasant taste.

As used herein, “organic acid” means an organic compound having acidic properties (e.g., according to the Bronsted-Lowry definition or the Lewis definition). Common organic acids are carboxylic acids, whose acidity is associated with their carboxyl group (-COOH). Dicarboxylic acids have two carboxylic acid groups. The relative acidity of an organic substance is measured by its pKa value, and those skilled in the art know how to determine the acidity of an organic acid based on a given pKa value.

In this specification, “aerosol” means fine particles of solid or liquid suspended in the air. In electronic cigarettes, the components are vaporized through heating, and then inhaled as aerosols in the form of small liquid droplets through condensation.

In this specification, the “aerosol target substance” refers to a substance to be inhaled in the form of an aerosol. Here, it refers to glycerin and propylene glycol, and the glycerin and propylene glycol are hydrophilic. The aerosol target substance is monovalent having one -OH group, divalent having two -OH groups, trivalent having three -OH groups, and polyvalent having two or more -OH groups.

Examples of the above monohydric substances may include alcohols (monohydric alcohols), and examples thereof include methanol, ethanol, isopropyl alcohol (propan-2-ol), butanol (butan-1-ol), pentanol (pentan-1-ol), and cetyl alcohol (hexadecan-1-ol).

Examples of the above dihydric substances may include alcohols (dihydric alcohols), and examples thereof include ethylene glycol (1,2-Ethanediol), propylene glycol (propane-1,2-diol), 1,3-propanediol, 1,4-butanediol, 1,5-pentanediol, and 1,6-hexanediol.

An example of the above trivalent substance may be alcohol (trihydric alcohol), and an example of this may be glycerol.

Examples of the above polyhydric substances may include polyhydric alcohols or polyols, and examples thereof include Erythritol, Threitol, Arabitol, Xylitol, Ribitol, Mannitol, Sorbitol, Galactitol, Fucitol, Iditol, Inositol, Menthol, Volemitol, Isomalt, Maltitol, Lactitol, Maltotriitol, Maltotetraitol, Pentaerythritol, Polyglycitol, Examples include polyglycerol, polypropylene glycol, and polyethylene glycol, as well as derivatives that contain or are processed from these, or naturally occurring derivatives.

As used herein, “electronic cigarette” or “e-cigarette” means an electronic inhaler that simulates the effects of smoking. There are many electronic cigarettes that do not at all resemble conventional cigarettes. The amount of nicotine contained can be selected by the user through inhalation. Typically, an electronic cigarette contains three essential components: a cartridge that acts as a mouthpiece and a container for storing the formulation, a heater, and a battery.

Method for manufacturing porous absorbent

In exemplary embodiments of the present invention, a method for manufacturing a porous absorbent is provided, including the steps of impregnating a porous absorbent with an eco-friendly powder aqueous solution or spraying an eco-friendly powder aqueous solution onto a porous absorbent to form a porous absorbent coated with eco-friendly powder; and the step of drying the porous absorbent coated with the eco-friendly powder to form a porous absorbent coated with eco-friendly powder.

The inventors of the present invention have discovered that a porous absorbent coated with an eco-friendly powder prevents leakage of a liquid composition for an electronic cigarette and provides an eco-friendly effect, and thus completed the present invention.

In one embodiment, the eco-friendly powder is derived from at least one selected from the group consisting of rice, wheat, potatoes, barley, beans, sorghum, sweet potatoes, mung beans, and glutinous rice. These are types of eco-friendly powders having a starch component containing amylopectin, and any eco-friendly material having a starch component can be used. The eco-friendly powder includes a polysaccharide containing a plurality of glucose units. Examples of the polysaccharide include starch, amylose, and amylopectin.

In one embodiment, the eco-friendly powder contains amylopectin. Amylopectin is a type of polysaccharide found in plants and is one of the main components of starch. Amylose, another polysaccharide, does not dissolve well in water, but amylopectin has the characteristic of soluble in water. The reason why amylopectin was selected as the coating material is, firstly, that it is an eco-friendly material that is harmless to the human body, and secondly, that it dissolves well in a solvent (water) that is easily available in the surroundings. The eco-friendly powder can use natural materials whose components have not been modified. The eco-friendly powder can use materials whose components have been modified to increase the amylopectin content.

In one embodiment, the eco-friendly powder may have a high amylopectin content of up to 100 wt%. The high amylopectin content may mean having amylopectin of 50 wt% or more.

“Low amylose” starches are not expected to be suitable because low amylose starches are generally broken down by the small intestine enzymes. Preferred starches have less than 50 wt % amylopectin. Particularly suitable starches have from about 25 wt % to about 35 wt % amylopectin, for example about 30 wt % amylopectin.

In one embodiment, the eco-friendly powder is dissolved in water at 80 to 150° C. This temperature range refers to a temperature range in which starch can be dissolved relatively quickly without burning.

In one embodiment, the content of the eco-friendly powder is 5 to 60 wt% based on the total weight of the eco-friendly powder aqueous solution. If the content of the eco-friendly powder is less than the lower limit, the amylopectin content is insufficient, and thus the coating of the porous absorbent is not completely formed. If the content of the eco-friendly powder exceeds the upper limit, the powder does not completely dissolve in water, and thus uniform coating by amylopectin is not formed.

In one embodiment, the step of forming a porous absorbent coated with the eco-friendly powder is performed by directly immersing the porous absorbent in water containing an amylopectin component dissolved therein or spraying the porous absorbent using a sprayer or the like, and then drying and coating the porous absorbent.

In one embodiment, the porous absorbent comprises at least one selected from the group consisting of metal silicate, alumina, halloysite, kaolinite, sericite, bentonite, quartzite and clay. The materials may be selectively used depending on the intended use of the porous absorbent. The porous absorbent may be used alone or in combination of two or more materials, and may be used by being made into spherical particles having a certain size range through a spray drying method.

In one embodiment, the metal-silicate comprises a metal ion derived from at least one selected from the group consisting of Mg, Al, Zr, Li, Ba, Na, and Ca. The materials are selectively used depending on the application, and are materials synthesized singly or in combination of two or more.

In one embodiment, the particle size of the eco-friendly powder is 5 to 500 μm. If it is less than the lower limit, the amount of powder added increases, and accordingly, it is difficult to spray dry the eco-friendly powder aqueous solution. In addition, if it exceeds the upper limit, the relative specific surface area of the powder decreases, and the bonding between the powders is not smooth, making it difficult to manufacture perfectly spherical granules.

In one embodiment, the specific surface area of the eco-friendly powder is 5 to 500 m ² /g. The specific surface area of the eco-friendly powder is related to the particle size of the eco-friendly powder.

In one embodiment, the step of forming a porous absorbent coated with the eco-friendly powder is performed by drying the porous absorbent coated with the eco-friendly powder at a temperature of room temperature to 150° C. or lower for 1 to 2 hours.

porous absorbent

In exemplary embodiments of the present invention, a porous absorbent body manufactured by the above manufacturing method is provided. The porous absorbent body according to the present invention can prevent leakage of a liquid composition for an electronic cigarette much better than conventional liquid electronic cigarettes.

In one embodiment, the porous absorbent forms a liquid storage portion that stores a liquid composition for an electronic cigarette therein. FIG. 1 is a schematic diagram showing the structure of a cartridge for an electronic cigarette according to one embodiment of the present invention. According to FIG. 1, the porous absorbent according to the present invention is a cartridge-type porous absorbent, which is a ceramic porous body having a space capable of storing a liquid component. Different materials for each part may be applied depending on the intended use. The coating according to the present invention refers to a coating of the body and the bottom portion excluding the head portion (liquid injection portion), and its main purpose is to prevent leakage of the liquid.

The above liquid composition for an electronic cigarette comprises an active ingredient and an aerosol forming agent.

In one embodiment, the active ingredient is at least one selected from the group consisting of nicotine, caffeine, taurine, theine, vitamins, melatonin, and cannabinoids. When the active ingredient is nicotine, the nicotine and the acid component form a nicotine salt, or the nicotine is in a free base nicotine state.

When nicotine and an acid component react to form a nicotine salt, it is a polar substance that dissolves well in hydrophilic components, so it can dissolve well in polymers and polar solvents that exhibit hydrophilic portions. A salt is an ionic compound that is divided into (+) and (-) charges when dissolved in a solvent. In the case of a nicotine salt, it forms a salt by meeting nicotine in a specific molar ratio depending on the type of acid component. Nicotine exhibits a (+) charge by taking a proton (H ⁺ ) of the acid component, and the acid component exhibits a (-) charge by giving up a proton (H ⁺ ). These two components form a compound through a certain ratio to exhibit electrical neutrality. Ionic compounds can dissolve in polar solvents as they dissociate into ions, and solidifying agents that have hydrophilic portions form ionic bonds, hydrogen bonds, and van der Waals forces with them to solidify in the form of a solid.

The above “acid component” is an organic acid added to change free-base nicotine into nicotine salt.

In one embodiment, the aerosol former is at least one selected from the group consisting of glycerol, sorbitol, propylene glycol, triethylene glycol, lactic acid, diacetin, triacetin, triethylene glycol diacetate, triethyl citrate, ethyl myristate, isopropyl myristate, methyl stearate, dimethyl dodecanedioate, and dimethyl tetradecanedioate.

In one embodiment, the acid component is at least one selected from the group consisting of benzoic acid, lactic acid, salicylic acid, lauric acid, sorbic acid, levulinic acid, pyruvic acid, formic acid, acetic acid, propionic acid, butyric acid, valeric acid, caproic acid, caprylic acid, capric acid, citric acid, myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, linolenic acid, phenylacetic acid, tartaric acid, succinic acid, fumaric acid, gluconic acid, saccharic acid, malonic acid, and malic acid. In one embodiment, the acid component comprises a carboxylic acid, a sulfinic acid, a sulfonic acid, an alcohol, an amino acid, a phenol, a thiophenol, an oxime, an enol, an imide, an aromatic sulfonamide, a primary nitro compound, a secondary nitro compound, other organic acids and inorganic acids, or a derivative processed thereof such as an ester, a naturally occurring derivative, or a combination including at least one of these. Organic acids corresponding to carboxylic acid and amino acids are most suitable for use.

Examples of the above carboxylic acids and carboxylic acid derivatives include carboxylic acids having one carbon atom, examples of which include formic acid and carbonic acid; carboxylic acids having two carbon atom ... 2,3-dioxopropanoic acid, malonic acid, tartronic acid, dihydroxymalonic acid, mesoxalic acid, glycidic acid, alanine, serine, and carboxylic acids with four carbon atoms may be included, examples of which include butyric acid, isobutyric acid, crotonic acid, isocrotonic acid, (methacrylic acid), vinylacetic acid, tetrolic acid, 2-hydroxybutyric acid, β-hydroxybutyric acid, γ-hydroxybutyric acid, Alpha-ketobutyric acid, acetoacetic acid, succinic semialdehyde, succinic acid, methylmalonic acid, fumaric acid, maleic acid, acetylenedicarboxylic acid, malic acid, tartaric acid, oxaloacetic acid, dioxosuccinic acid, asparagine, aspartic acid, threonine, and carboxylic acids with 5 carbon atoms can be included, examples of which include valeric acid, isovaleric acid, 2-methylbutanoic acid, pivalic acid, β-hydroxyvaleric acid, γ-hydroxyvaleric acid, β-hydroxy-β-methylbutyric acid, glutaric acid, α-ketoglutaric acid, 2-hydroxyglutaric acid, 3-hydroxyglutaric acid, acetonedicarboxylic acid, 2-furoic acid, tetrahydro-2-furoic acid, glutamate, methionine, proline, valine, and carboxylic acids with six carbon atoms may be included, examples of which include caproic acid, Adipic acid, 2,3-dimethylbutanoic acid, 3,3-dimethylbutanoic acid, citric acid, aconitic acid, isocitric acid, sorbic acid, gluconic acid, nicotinic acid (niacin), 2-hydroxyisocaproic acid, arginine, histidine, and carboxylic acids with 7 carbon atoms can be included, and examples of these include enanthic acid, pimelic acid, cyclohexanecarboxylic acid, benzoic acid, salicylic acid, and 3-hydroxybenzoic acid. 4-hydroxybenzoic acid, 2,3-dihydroxybenzoic acid, 2,4-dihydroxybenzoic acid, 2,5-dihydroxybenzoic acid (gentisic acid), 2,6-dihydroxybenzoic acid, 3,4-dihydroxybenzoic acid (protocatechuic acid), 3,5-dihydroxybenzoic acid, 2,4,6-Trihydroxybenzoic acid, leucine, isoleucine, lysine, gallic acid, 2,2-dimethylpentanoic acid, 2,3-dimethylpentanoic acid, 2,4-dimethylpentanoic acid, 3,3-dimethylpentanoic acid, 2-ethylpentanoic acid, 3-ethylpentanoic acid, 2-methylhexanoic acid, 3-methylhexanoic acid, 2,2,3-trimethylbutanoic acid, 2-ethyl-2-methylbutanoic acid, 2-ethyl-3-methylbutanoic acid, and carboxylic acids with 8 carbon atoms may be applicable, and examples of these include caprylic acid, phthalic acid, isophthalic acid, terephthalic acid, phenylacetic acid, vanillin, vanillic acid, homogentisic acid, orsellinic acid, and 2-methylheptanoic acid. acid, 3-methylheptanoic acid, 4-methylheptanoic acid, 5-methylheptanoic acid, 6-methylheptanoic acid, 2,2-dimethylhexanoic acid, 2,3-dimethylhexanoic acid, 2,4-dimethylhexanoic acid, 2,5-dimethylhexanoic acid, 3,3-dimethylhexanoic acid, 3,4-dimethylhexanoic acid, 3,5-dimethylhexanoic acid, 4,4-dimethylhexanoic acid, 4,5-dimethylhexanoic acid, 5,5-dimethylhexanoic acid, 2-ethanehexanoic acid, 3-ethanehexanoic acid, 4-ethanehexanoic acid, 5-ethaneehexanoic acid, 2-octenoic acid, 3-octenoic acid, 4-octenoic acid, 5-octenoic acid, 6-octenoic acid, 7-octenoic acid, carboxylic acids with 9 carbon atoms can be applicable, examples of which include pelargonic acid, trimesic acid, cinnamic acid, acetylsalicylic acid, phenylalanine, tyrosine, syringic acid, caffeic acid, coumaric acid, and levodopa, carboxylic acids with 10 carbon atoms can be applicable, examples of which include decanoic acid (capric acid), sebacic acid, eudesmic acid, α-Cyano-4-hydroxycinnamic acid, and ferulic acid, carboxylic acids with 11 carbon atoms can be applicable, examples of which include undecanoic acid. Examples of carboxylic acids that can be included include tryptophan, 5-hydroxytryptophan, and sinapinic acid. Examples of carboxylic acids that can be included include lauric acid and mellitic acid. Examples of carboxylic acids that can be included include 13 carbon atoms, such as tridecylic acid and 4-Hydroxybenzoic acid 4-O-glucoside. Examples of carboxylic acids that can be included include 14 carbon atoms, such as myristic acid, chebulic acid, theogallin, and ellagic acid. Examples of carboxylic acids that can be included include 15 carbon atoms, such as pentadecanoic acid. Examples of carboxylic acids that can be included include 16 carbon atoms. Examples of such acids include palmitic acid and chlorogenic acid; carboxylic acids with 17 carbon atoms include heptadecanoic acid; carboxylic acids with 18 carbon atoms include stearic acid, oleic acid, linoleic acid, α-linolenic acid, γ-linolenic acid, and stearidonic acid; carboxylic acids with 19 carbon atoms include nonadecylic acid; carboxylic acids with 20 carbon atoms include arachidic acid, mead acid, and arachidonic acid; Examples of carboxylic acids that can be included include eicosapentaenoic acid (EPA), pimaric acid, and carboxylic acids with 21 carbon atoms, such as heneicosanoic acid; examples of carboxylic acids that can be included include behenic acid, docosahexaenoic acid (DHA), and chicoric acid; examples of carboxylic acids that can be included include tricosylic acid; examples of carboxylic acids that can be included include lignoceric acid, cholic acid, deoxycholic acid, chenodeoxycholic acid, and lithocholic acid; and examples of carboxylic acids that can be included include lignoceric acid, cholic acid, deoxycholic acid, chenodeoxycholic acid, and lithocholic acid; and examples of carboxylic acids that can be included include 25 carbon atoms. It may be applicable, and an example of this is pentacosanoic acid, and a carboxylic acid having 26 carbon atoms may be applicable, and an example of this is cerotic acid, glycocholic acid, glycochenodeoxycholic acid, etc., or a processed derivative thereof, a naturally occurring derivative thereof, or a combination comprising at least one of these.

The derivatives of the above acid component include ethyl protocatechuate, bergenin, ethyl gallate, norbergenin, coumarin, esters of acids, or derivatives processed thereof, or naturally occurring derivatives thereof, or combinations including at least one of these.

The above sulfinic acid and sulfinic acid derivatives include phenylsulfinic acid, formamidinesulfinic acid (Thiourea dioxide), hypotaurine, Rongalite, sulfinate, etc., or derivatives processed thereof, derivatives naturally occurring thereof, or combinations including at least one of these.

The above sulfonic acids and sulfonic acid derivatives include perfluorooctanesulfonic acid, vinylsulfonic acid, p-toluenesulfonic acid, benzenesulfonic acid, methanesulfonic acid, Taurochenodeoxycholic acid, taurocholic acid, perfluorooctanesulfonic acid, Nafion, Sodium dodecylbenzenesulfonate, alkylbenzenesulfonate, Coenzyme M, Sulfate, etc., or are composed of processed derivatives thereof, naturally occurring derivatives thereof, or a combination including at least one or more of these.

The above amino acids and amino acid derivatives include Glycine, Alanine, Valine, Isoleucine, Leucine, Phenylalanine, Proline, Serine, Threonine, Asparagine, Glutamine, Cysteine, Methionine, Phenylalanine, Tyrosine, Tryptophan, Aspartate, Glutamic acid, Histidine, Lysine, Arginine, Selenocysteine, Pyrrolysine, etc., or their processed derivatives or naturally occurring derivatives. A derivative or a combination including at least one of these.

The type of the acid component can be determined by the vapor pressure of the acid component. The solid according to one embodiment of the present invention comprises an acid component having a vapor pressure similar to the vapor pressure of free base nicotine. The solid according to one embodiment of the present invention is formed from an acid component having a vapor pressure similar to the vapor pressure of free base nicotine at a heating temperature. A nicotine salt formed from nicotine and benzoic acid; nicotine and salicylic acid; or nicotine and levulinic acid is a salt that produces a satisfaction in an individual user consistent with efficient delivery of nicotine and a rapid rise in nicotine plasma levels. If the nicotine and acid components have similar vapor pressures, they are simultaneously aerosolized, delivering both free base nicotine and the acid component to the user. The acid component can have a vapor pressure of 20-4000 mmHg at 200° C. The acid component for the solid according to one embodiment of the present invention can have a vapor pressure of 20 to 200 mmHg at 200° C., and is non-corrosive to the electronic cigarette or non-toxic to humans. In some embodiments, the suitable acid for forming the nicotine salt is selected from the group consisting of salicylic acid, benzoic acid, lauric acid, and levulinic acid. If an acid component having a lower vapor pressure than nicotine at a specific temperature is used, the acid component does not sufficiently vaporize and form an aerosol upon heating. Since it does not exist in the aerosol together with free base nicotine, nicotine is not sufficiently protonated. The hit and unpleasant taste of free base nicotine increase (vapor pressure: pyruvic acid > benzoic acid > lauric acid).

The type of the acid component can be determined by the melting point and boiling point of the acid component. It may have a melting point <160°C, a boiling point >160°C, a difference between the melting point and the boiling point of 50°C or more, and is non-corrosive to the electronic cigarette or non-toxic to humans. In some embodiments, the suitable acid for forming a nicotine salt has a melting point at least 40°C lower than the operating temperature of the electronic cigarette, a boiling point no more than 40°C lower than the operating temperature of the electronic cigarette, a difference between the melting point and the boiling point of 50°C or more, and is non-corrosive to the electronic cigarette or non-toxic to humans; wherein the operating temperature is 200°C. In some embodiments, the suitable acid for forming a nicotine salt is selected from the group consisting of salicylic acid, sorbic acid, benzoic acid, pyruvic acid, lauric acid, and levulinic acid.

In one embodiment, the stoichiometric ratio of the nicotine and acid components is 1:1, 1:2, 1:3, 1:4, 2:3, 2:5, 2:7, 3:4, 3:5, 3:7, 3:8, 3:10, 3:11, 4:5, 4:7, 4:9, 4:10, 4:11, 4:13, 4:14, 4:15, 5:6, 5:7, 5:8, 5:9, 5:11, 5:12, 5:13, 5:14, 5:16, 5:17, 5:18 or 5:19.

The sensation known as the “throat hit” due to nicotine in the inhaled vapor can be controlled by the stoichiometric ratio of the above nicotine and acid components. If more acid components are added than a certain molar ratio, the pH is lowered, the throat hit is reduced, and the soft characteristic increases. If more acid components are added to the component with a molar ratio of 1:1 to form a molar ratio of 1:2 or 1:3, the protonation of nicotine increases, further reducing the throat hit, so the intensity can be controlled by controlling the amount of acid added. Nicotine salts are absorbed more slowly than stem nicotine, so there is less of a sudden throat hit, and since they have a soft characteristic, the sensory region for nicotine absorption can be controlled by controlling the ratio of nicotine salts. The more acid components are added, the greater the ratio of nicotine salts, so they have a softer characteristic. When more acid components are added to a nicotine salt with a 1:1 bond, an acid component with a 1:2 bond also exists, which exhibits a softer characteristic. As the pH decreases, nicotine and nicotine salts are additionally protonated, so it takes more time for the protons to dissociate when absorbed by the human body, so it is absorbed late and has a softer characteristic. The absorption rate of diprotonated nicotine salts is slower than that of monoprotonated nicotine salts, so the impact is reduced and it gives a softer feeling. When the acid component is insufficient, free base nicotine that is not protonated remains, so the impact and unpleasant taste increase.

The degree of protonation of the nicotine molecule depends on the stoichiometric ratio of the nicotine and acid components in the salt formation reaction. The degree of protonation of the nicotine molecule can also vary with the solvent. In some embodiments, monoprotonated nicotine salts produce a high degree of user satisfaction. For example, nicotine benzoate and nicotine salicylate are monoprotonated nicotine salts and both produce a high degree of user satisfaction. The reason for this tendency can be explained by a mechanism of action in which nicotine is first deprotonated before being delivered into the vapor along with the acid component, and then is maintained and stabilized after being reprotonated by the acid as it travels downstream into the user's lungs. It may be easier to remove one proton than two protons, and thus a better delivery efficiency is obtained. Nicotine salts may perform best when they are in the optimal protonation range for the salt. For example, nicotine pyruvate is a nicotine salt having a nicotine:acid ratio of 1:2. A formulation containing nicotine pyruvate (1:2) can deliver a higher level of satisfaction to the user than one containing the same amount of nicotine but only half the amount of pyruvate, i.e. nicotine pyruvate (1:1). This can be explained by the fact that one mole of nicotine forms a salt with two moles of pyruvate. When there is not enough pyruvate to associate with all the nicotine molecules, the free base nicotine remaining in the formulation that is not protonated can reduce the level of satisfaction provided by the formulation.

Cartridges and electronic cigarettes

In exemplary embodiments of the present invention, a cartridge for an electronic cigarette is provided, comprising the porous absorbent material.

In exemplary embodiments of the present invention, an electronic cigarette is provided, comprising the cartridge for the electronic cigarette.

Hereinafter, the present invention will be described in detail with reference to preferred embodiments so that those skilled in the art can easily practice the present invention. However, the present invention may be implemented in various different forms and is not limited to the embodiments described herein.

{Example}

<Manufacturing Example> Manufacturing of porous absorbent material

A beaker was filled with 400 ml of water, placed on a hot plate, and heated at 120°C for 10 minutes. Then, 50 to 200 g of glutinous rice powder was added, and heated for 30 minutes until completely dissolved to obtain a glutinous rice powder aqueous solution.

A cartridge-shaped porous absorbent containing metal (Mg)-silicate was prepared with a structure as in Fig. 1. The porous absorbent was immersed in a glutinous rice powder aqueous solution at 80 to 90°C for 5 seconds to form a porous absorbent coated with an eco-friendly powder. Subsequently, the porous absorbent coated with the eco-friendly powder was dried in a dryer at a temperature of 80 to 100°C for 1 to 2 hours to form a porous absorbent coated with an eco-friendly powder.

<Experimental Example 1> Evaluation of the Appearance of Porous Hygroscopic Body

The appearance of the porous absorbent manufactured in the manufacturing example was visually evaluated. The results are shown in FIGS. 2a and 2b. FIGS. 2a and 2b are photographs showing the appearance of the porous absorbent before and after coating according to one embodiment of the present invention. FIG. 2a shows the porous absorbent before coating, and FIG. 2b shows the porous absorbent after coating.

From FIGS. 2a and 2b, it can be confirmed that the eco-friendly powder is uniformly coated on the porous absorbent according to the present invention.

<Experimental Example 3> Evaluation of liquid absorption characteristics of porous absorbents

The liquid absorption state of the porous absorbent manufactured in the manufacturing example was evaluated. More specifically, after dropping a drop of water on the porous absorbent, the liquid absorption state over time was visually evaluated. The results are shown in FIGS. 3a and 3b. FIGS. 3a and 3b are photographs showing the liquid absorption state over time of the porous absorbent according to one embodiment of the present invention. FIG. 3a shows the liquid absorption state of the uncoated porous absorbent (time points at 0 sec 00, 0 sec 38, 0 sec 72, 1 sec 75, and 3 sec 59, respectively), and FIG. 3b shows the liquid absorption state of the coated porous absorbent (time points at 0 sec 00, 0 sec 30, 0 sec 87, 5 sec 68, and 8 sec 85, respectively).

From FIGS. 3a and 3b, it can be confirmed that the coating power of the porous absorbent according to the present invention is excellent, thereby preventing leakage of the liquid composition for an electronic cigarette.

While exemplary embodiments of the present invention have been described above with respect to the above-mentioned preferred embodiments, it will be appreciated that various modifications and variations may be made without departing from the spirit and scope of the invention. Accordingly, the appended claims will encompass such modifications and variations as fall within the spirit of the invention.

Claims (13)

A step of impregnating a porous absorbent with an eco-friendly powder solution or spraying an eco-friendly powder solution onto a porous absorbent to form a porous absorbent coated with an eco-friendly powder; and
A step of drying the porous absorbent coated with the eco-friendly powder to form a porous absorbent coated with the eco-friendly powder;
The above porous absorbent material stores a liquid composition for an electronic cigarette inside,
The above eco-friendly powder contains amylopectin,
A method for producing a porous absorbent, the method comprising: producing a porous absorbent derived from at least one selected from the group consisting of rice, wheat, potatoes, barley, soybeans, sorghum, sweet potatoes, mung beans, and glutinous rice. delete delete In the first paragraph,
A manufacturing method wherein the above-mentioned eco-friendly powder is dissolved in water at 80 to 150°C, and the content of the above-mentioned eco-friendly powder is 5 to 60 wt% based on the total weight of the eco-friendly powder aqueous solution. delete delete In the first paragraph,
The particle size of the above eco-friendly powder is 5 to 500 μm,
A manufacturing method wherein the surface area of the above eco-friendly powder is 5 to 500 m ² /g. delete In the first paragraph,
A manufacturing method, wherein the step of forming a porous absorbent coated with the above-mentioned eco-friendly powder is performed by drying the porous absorbent coated with the above-mentioned eco-friendly powder at a temperature of room temperature to 150°C or lower for 1 to 2 hours. A porous absorbent manufactured by the manufacturing method of any one of claims 1, 4, 7 and 9. delete A cartridge for an electronic cigarette, comprising the porous absorbent of claim 10. An electronic cigarette comprising a cartridge for an electronic cigarette according to claim 12.