KR20040047215A - 소의 유선염 치료방법 및 치료제 - Google Patents
소의 유선염 치료방법 및 치료제 Download PDFInfo
- Publication number
- KR20040047215A KR20040047215A KR1020020075342A KR20020075342A KR20040047215A KR 20040047215 A KR20040047215 A KR 20040047215A KR 1020020075342 A KR1020020075342 A KR 1020020075342A KR 20020075342 A KR20020075342 A KR 20020075342A KR 20040047215 A KR20040047215 A KR 20040047215A
- Authority
- KR
- South Korea
- Prior art keywords
- cow
- carrier
- mastitis
- casein
- milk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 208000004396 mastitis Diseases 0.000 title claims abstract description 18
- 238000000034 method Methods 0.000 title claims abstract description 15
- 241000283690 Bos taurus Species 0.000 title claims description 29
- 239000000203 mixture Substances 0.000 title claims 2
- 210000000481 breast Anatomy 0.000 title abstract description 14
- 239000005018 casein Substances 0.000 claims abstract description 22
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims abstract description 22
- 235000021240 caseins Nutrition 0.000 claims abstract description 22
- 239000006260 foam Substances 0.000 claims abstract description 19
- 230000000845 anti-microbial effect Effects 0.000 claims abstract description 10
- 210000005075 mammary gland Anatomy 0.000 claims abstract description 10
- 239000000126 substance Substances 0.000 claims abstract description 8
- 239000004599 antimicrobial Substances 0.000 claims abstract description 7
- 230000006835 compression Effects 0.000 claims abstract description 7
- 238000007906 compression Methods 0.000 claims abstract description 7
- 244000005700 microbiome Species 0.000 claims abstract description 6
- 231100000252 nontoxic Toxicity 0.000 claims abstract description 5
- 230000003000 nontoxic effect Effects 0.000 claims abstract description 5
- 239000003755 preservative agent Substances 0.000 claims abstract description 5
- 230000002335 preservative effect Effects 0.000 claims abstract description 5
- 235000019871 vegetable fat Nutrition 0.000 claims abstract description 3
- 238000002347 injection Methods 0.000 claims description 10
- 239000007924 injection Substances 0.000 claims description 10
- 210000002445 nipple Anatomy 0.000 claims description 10
- 208000031462 Bovine Mastitis Diseases 0.000 claims description 3
- 238000005507 spraying Methods 0.000 claims description 3
- 102000011632 Caseins Human genes 0.000 claims 2
- 108010076119 Caseins Proteins 0.000 claims 2
- 235000020247 cow milk Nutrition 0.000 claims 1
- 239000002075 main ingredient Substances 0.000 claims 1
- 239000008267 milk Substances 0.000 abstract description 27
- 210000004080 milk Anatomy 0.000 abstract description 27
- 239000003814 drug Substances 0.000 abstract description 8
- 239000003242 anti bacterial agent Substances 0.000 abstract description 7
- 229940088710 antibiotic agent Drugs 0.000 abstract description 6
- 244000144972 livestock Species 0.000 abstract description 4
- 229940124597 therapeutic agent Drugs 0.000 abstract description 4
- 241000283707 Capra Species 0.000 abstract description 3
- 239000007921 spray Substances 0.000 abstract description 3
- 241001465754 Metazoa Species 0.000 abstract description 2
- 238000001802 infusion Methods 0.000 abstract description 2
- 230000000694 effects Effects 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 description 22
- 108010062877 Bacteriocins Proteins 0.000 description 15
- 239000002674 ointment Substances 0.000 description 9
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 8
- 239000006199 nebulizer Substances 0.000 description 7
- 241000894006 Bacteria Species 0.000 description 6
- 230000003115 biocidal effect Effects 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 235000014655 lactic acid Nutrition 0.000 description 4
- 239000004310 lactic acid Substances 0.000 description 4
- 210000004216 mammary stem cell Anatomy 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 238000005187 foaming Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 102000044503 Antimicrobial Peptides Human genes 0.000 description 1
- 108700042778 Antimicrobial Peptides Proteins 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical group [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 229940127089 cytotoxic agent Drugs 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000036186 satiety Effects 0.000 description 1
- 235000019627 satiety Nutrition 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0041—Mammary glands, e.g. breasts, udder; Intramammary administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/122—Foams; Dry foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
Claims (5)
- 항균물질과 거품(foaming)을 형성하는 캐리어가 혼합되어 압축 내장된 압축용기가 구비되고, 상기 압축용기와 연통된 주입관을 소의 유두관에 삽입한 후, 상기 항균물질이 혼합된 캐리어를 젖소의 유선조직내로 분사하여서 젖소의 유선염을 치료하는 것을 특징으로 하는 소의 유선염 치료방법.
- 제1항에 있어서, 상기 항균물질은 미생물이 생산하는 무독성 방부제인 박테리오신(bacteriosins)인 것을 특징으로 하는 소의 유선염 치료방법.
- 제1항에 있어서, 상기 캐리어는 카세인(casein)을 주성분으로 하여 상기 유두관 내부에서 발포(發泡)되는 것을 특징으로 하는 소의 유선염 치료방법.
- 제1항에 있어서, 상기 캐리어는 식물성 지방을 주성분으로 하여 상기 유두관 내부에서 발포(發泡)되는 것을 특징으로 하는 소의 유선염 치료방법.
- 소의 유선염을 치료하는 조성물에 있어서, 미생물이 생산하는 무독성 방부제인 박테리오신(bacteriosins)인 항균물질;과 카세인(casein)을 주성분으로 하여 소의 유두관 내부에서 발포(發泡)되는 캐리어;가 포함되는 것을 특징으로 하는 소의 유선염 치료제.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020020075342A KR20040047215A (ko) | 2002-11-29 | 2002-11-29 | 소의 유선염 치료방법 및 치료제 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020020075342A KR20040047215A (ko) | 2002-11-29 | 2002-11-29 | 소의 유선염 치료방법 및 치료제 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20040047215A true KR20040047215A (ko) | 2004-06-05 |
Family
ID=37342643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020020075342A Ceased KR20040047215A (ko) | 2002-11-29 | 2002-11-29 | 소의 유선염 치료방법 및 치료제 |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR20040047215A (ko) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4983634A (en) * | 1987-12-24 | 1991-01-08 | Corby Michael P | Treatment of mastitis and applicator therefor |
| WO1991000030A1 (de) * | 1989-06-30 | 1991-01-10 | Waldemar Voigt | Schmuckblende |
| KR19990022064A (ko) * | 1995-06-07 | 1999-03-25 | 스폰 벤자민 티. | 습식 박테리오신 소독 와이프 및 이의 사용방법 |
| JPH11146799A (ja) * | 1997-09-10 | 1999-06-02 | Snow Brand Milk Prod Co Ltd | 新規プライマー及びその利用 |
-
2002
- 2002-11-29 KR KR1020020075342A patent/KR20040047215A/ko not_active Ceased
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4983634A (en) * | 1987-12-24 | 1991-01-08 | Corby Michael P | Treatment of mastitis and applicator therefor |
| WO1991000030A1 (de) * | 1989-06-30 | 1991-01-10 | Waldemar Voigt | Schmuckblende |
| KR19990022064A (ko) * | 1995-06-07 | 1999-03-25 | 스폰 벤자민 티. | 습식 박테리오신 소독 와이프 및 이의 사용방법 |
| JPH11146799A (ja) * | 1997-09-10 | 1999-06-02 | Snow Brand Milk Prod Co Ltd | 新規プライマー及びその利用 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 20021129 |
|
| PA0201 | Request for examination | ||
| PG1501 | Laying open of application | ||
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20040930 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20050628 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20040930 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |