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KR20040065524A - 백혈병을 검사 및 치료하는 방법 - Google Patents

백혈병을 검사 및 치료하는 방법 Download PDF

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KR20040065524A
KR20040065524A KR10-2003-7009841A KR20037009841A KR20040065524A KR 20040065524 A KR20040065524 A KR 20040065524A KR 20037009841 A KR20037009841 A KR 20037009841A KR 20040065524 A KR20040065524 A KR 20040065524A
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라포니미취
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오르토-클리니칼 다이아그노스틱스, 인코포레이티드
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Abstract

백혈병 환자를 치료하는 방법은 환자의 유전자 발현 프로필을 분석하여 상기 환자가 파네실 트란스퍼라제 저해제(FTI) 및 선택적으로, 다른 치료제 치료에 반응할 것 같은지를 결정하는 단계를 포함한다. 상기 발명은 또한 환자 치료를 모니터링하는데 및 치료 과정을 선택하는데 유용하다. FTI에 반응하여 조절되는 유전자가 제공되며, 상기 프로필을 제제화하는데 사용된다.

Description

백혈병을 검사 및 치료하는 방법{Method for assessing and treating leukemia}
암과 연관된 Ras와 같은, 일부 분자는 세포의 원형질 막의 내측 소엽(leaflet)과 반응하고 다양한 신호전달 경로에 관여하기 위하여 파네실 전이 효소(farnesyl transferase enzyme)에 의하여 파네실화되어야 한다. Ras는 프레닐화된 CAAX 박스를 가지며 암과 연관된 유일한 단백질인 것은 아니다. 파네실 전이효소 저해제(Farnesyl transferase inhibitor)(FTI)는 다양한 단백질의 C-말단 CAAX 모티프에 탄소 파네실 부위가 공유적으로 결합하는 것을 저해하는 치료제이다. 이들은 암 및 백혈병과 같은 증식성 질환에 유용하다. 급성 골수백혈병(Acute myelogenous leukemia)(AML)은 FTI에 의하여 가장 유익하게 처리될 수 있는 질병 중의 하나이다.
많은 치료 요법에 있어서와 마찬가지로, 일부 환자는 FTI 치료에 반응하나 일부는 그렇지 않다. 반응할 것 같지 않은 환자에게 치료를 처방하는 것은 바람직하지 않다. 따라서, 무반응자가 불필요하게 치료되지 않도록 하고, 약물로부터 가장 큰 이익을 받을 가능성이 있는 환자가 적절하게 치료되고 모니터링될 수 있도록 하기 위하여, 약물이 투여되기 전에 환자가 그러한 치료에 어떻게 반응할 것인지를 아는 것은 유용하다. 더욱이, 치료에 반응하는 환자 중, 반응의 정도에 차이가 있을 수 있다. FTI 이외의 치료제로 치료하는 것 또는 FTI에 다른 치료제를 부가하여 치료하는 것이 FTI에 반응하지 않는 자 또는 FTI만에 대한 반응성이 원하는 것보다 낮은 환자에게는 유용할 수 있다.
본 출원은 하기 미국 가출원의 이익을 주장한다: 60/340,938; 60/338,997; 60/340,081; 및 60/341,012. 본 발명은 백혈병 세포의 유전자 발현 프로필에 근거한 백혈병의 진단, 예후(prognostics), 및 치료에 관한 것이다.
도 1은 본 발명의 유전자 발현 프로필을 분석하기 위하여 사용되는 유전자 발현 패턴의 그래프 표시의 일 예이다.
도 2는 MAPK/ERK 경로의 도식적 다이아그램이다.
도 3은 TGFβ 및 Wnt 경로의 도식적 다이아그램이다.
도 4는 세포자가사 경로의 도식적 다이아그램이다.
본 발명은 FTI로 백혈병 환자를 치료하는 방법이다. 그러한 일 방법에 있어서, 환자의 유전자 발현 프로필을 분석하여 환자가 FTI에 반응할 것 같은지를 결정하고, 상기 환자가 반응할 것 같으면, 상기 환자를 FTI로 치료한다.
본 발명의 또다른 태양에 있어서, FTI 치료를 위하여 백혈병 환자를 모니터링하는 것으로서, 상기 환자의 유전자 발현 프로필을 분석하여 상기 환자가 FTI에 반응할 것 같은지를 결정하고, 환자가 바람직한 방식으로 반응할 것 같으면, FTI로 환자를 치료한다.
본 발명의 또다른 태양에 있어서, 상기 유전자 발현 프로필이 FTI 반응자(responder)를 표시하는 하나이상의 특정 유전자의 상향 조절(up regulation)을 나타내면, 환자를 치료한다.
본 발명의 또다른 태양에 있어서, FTI 반응자를 표시하는 유전자 발현 프로필은 FTI 비반응자(non-responder)에 비하여 1.5, 1.7, 또는 2 배이상의 차이를 보이는 환자이다.
본 발명의 또다른 태양에 있어서, 상기 유전자 발현 프로필이 FTI 반응자를 표시하는 하나이상의 특정 유전자의 하향 조절(down regulation)을 나타내면, 환자를 치료한다.
본 발명의 또다른 태양에 있어서, 상기 유전자 발현 프로필이 하기 표 1-3의 유전자 군으로부터 선택되는 유전자의 조절(modulation)을 나타내면, 환자를 치료한다.
본 발명의 또다른 태양에 있어서, 상기 FTI는 퀴놀린 또는 퀴놀린 유도체이다.
본 발명의 또다른 태양에 있어서, 상기 FTI는 (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)이다.
상기 방법을 실시하는데 사용되는 물품(article)도 또한 본 발명의 일 태양이다. 그러한 물품은 컴퓨터 판독 가능한 매체에 고정된 유전자 발현 프로필 또는 그의 표현물(representation)이 포함된다. 본 발명에 따른 다른 물품에는 본 발명의 상기 유전자 발현 프로필을 결정하기 위하여 사용되는 핵산 어레이를 포함한다.
본 발명의 또다른 태양에 있어서, 백혈병 환자를 치료하는 방법은 FTI 및 MAPK/ERK 신호전달 경로, TGFβ, WNT 또는 세포자가사 경로를 조절하는 치료용 조성물을 투여하는 단계를 포함한다.
본 발명의 또다른 태양에 있어서, 상기 환자는 FTI 및 티로신 키나제 저해제, MEK 키나제 저해제, PI3K 키나제 저해제, MAP 키나제 저해제, 세포자가사(apoptosis) 조절인자, 및 그의 조합물로 이루어지는 군으로부터 선택되는 치료용 조성물로 치료된다.
본 발명의 또다른 태양에 있어서, 백혈병 환자의 유전자 발현 프로필을 분석하여 상기 환자가 FTI에 반응할 것 같은지를 결정하거나, 상기 환자가 FTI와 다른 약물의 조합으로부터 이득을 얻을 수 있을 것 같은지를 결정한다. 다음으로, 상기 환자를 그러한 조합으로 치료하거나, 상기 환자가 FTI에 반응할 것 같지 않으면, 상기 환자를 티로신 키나제 저해제, MEK 키나제 저해제, PI3K 키나제 저해제, MAP 키나제 저해제, 세포자가사 조절인자, 및 그의 조합물로 이루어지는 군으로부터 선택되는 약물로 치료한다.
본 명세서에 언급되는 상기 "치료제(therapeutic agent)"는 FTI이다. FTI는 복수의 형태를 띠고 있으나, 암과 증식성 질병과 연관된 단백질의 파네실화를 저해하거나 감소시키는 필수적 저해기능을 공유한다.
바람직하게는, 상기 FTI는 AML과 같은 백혈병의 치료용으로 표시되는 것들이다. FTI에 반응하는 환자는 FTI로 치료한 후, 골수에서 50%이상의 모세포(blast cell)의 감소를 보이는 환자이다.
많은 FTI가 본 발명의 범위 내에 있으며, 하기의 미국특허에 개시된 것들을 포함하며, 이들 미국특허 문헌 각각은 참조에 의하여 본 명세서에 포함된다.: Brown 등의 제5,976,851호; Anthony 등의 제5,972,984호; deSolms 등의 제5,972,966호; Dinsmore 등의 제5,968,965호; Venet 등의 제5,968,952호 ; Venet등의 제6,187,786호; Venet 등의 제6,169,096호; Venet 등의 제6,037,350호; Angibaud 등의 제6,177,432호; Graham 등의 제5,965,578호; Sebti 등의 제5,965,539호; Afonso 등의 제5,958,939호; Anthony 등의 제5,939,557호; Commercon 등의 제5,936,097호; Anthony 등의 제5,891,889호; Baudin 등의 제5,889,053호; Anthony 등의 제5,880,140호; deSolms 등의 제5,872,135호; deSolms 등의 제5,869,682호; Baudoin 등의 제5,861,529호; Graham 등의 제5,859,015호; Clerc 등의 제5,856,439호; Anthony 등의 제5,856,326호; Graham 등의 제5,852,010호; Marsters 등의 제5,843,941호; Doll 등의 제5,807,852호; Dinsmore 등의 제3,780,492호; Dong 등의 제5,773,455호; Kim 등의 제5,767,274호; Anthony 등의 제5,756,528호; Baudoin 등의 제5,750,567호; Bishop 등의 제5,721,236호; Doll 등의 제5,700,806호; Anthony 등의 제5,661,161호; Sebti 등의 제5,602,098호; Breslin 등의 제5,585,359호; Ciccarone 등의 제5,578,629호; Ciccarone 등의 제5,534,537호; Marsters 등의 제5,532,359호; Patel 등의 제5,523,430호; de Solms 등의 제5,504,212호; deSolms 등의 제5,491,164호; Brown 등의 제5,420,245호; 및 Graham 등의 제5,238,922호. 비-펩티드성의, 소위 "소분자(small molecule)" 치료제가 바람직하다.
바람직한 FTI는 다음과 같은 퀴놀린 또는 퀴놀린 유도체이다:
7-(3-클로로페닐)-9-[(4-클로로페닐)-1H-이미다졸-1-일메틸]-2,3-디히드로- 1H,5H-벤조[ij]퀴놀리진-5-온,
7-(3-클로로페닐)-9-[(4-클로로페닐)-1H-이미다졸-1-일메틸]-1,2-디히드로-4H-피롤로[3,2,1-ij]퀴놀린-4-온,
8-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일),메틸]-6-(3-클로로페닐)1,2-디히드로-4H-피롤로[3,2,1-ij]퀴놀린-4-온,
8-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-6-(3-클로로페닐)-2,3-디히드로-1H,5H-벤조[ij]퀴놀리진-5-온.
가장 바람직한 FTI는 (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)이다.
FTI 및 다른 치료제로 백혈병을 치료하는 단계를 포함하는 본 발명의 일 태양에 있어서, 본 명세서에서 언급된 상기 치료제(therapeutic agent)는 퀴놀린-기초 FTI 치료를 받는 백혈병 세포(leukemic cell)의 유전자 발현 분석에 의하여 명확하게 된 생물학적 경로에 영향을 미치는 치료제이다.
게놈 내에 단백질 또는 펩티드를 발현할 수 있는 잠재성을 갖는 핵산 서열("유전자(genes)")이 단순히 존재한다고 하여, 단백질 또는 펩티드가 주어진 세포에서 발현될지 여부가 결정되는 것은 아니다. 주어진 유전자가 단백질 또는 펩티드를 그렇게 발현할 수 있는지 없는지 및 있다면, 어느 정도 그러한 발현이 일어날 수 있는지는, 다양한 복합 인자에 의하여 결정된다. 이러한 인자를 이해하고 검사하기가 어렵다는 점과는 별개로, 유전자 발현 분석은 약물 또는 다른 치료제의 도입과 같은 주어진 자극에 대한 세포 반응에 관한 유용한 정보를 제공할 수 있다. 유전자가 활성적이거나 불활성적인 정도의 상대적 표시를 유전자 발현 프로필에서 찾을 수 있다. 본 발명의 유전자 발현 프로필은 주어진 치료법으로부터 이득을 얻을 것같은 환자를 확인하고 치료하는데 또는 약물이나 치료법에 대하여 유익한 반응을 하지 않거나 거의 하지 않을 것 같은 환자를 상기 치료법으로부터 배제하는데 사용된다.
(관련 생물학적 경로를 밝혀내는데 사용되는 것을 포함한) 유전자 발현 프로필을 확립하는 바람직한 방법에는 단백질 또는 펩티드를 코딩할 수 있는 유전자에 의하여 생산되는 RNA의 양을 결정하는 단계를 포함한다. 이 방법은 역전사 PCR (RT-PCR), 경쟁적 RT-PCR, 실시간 RT-PCR, 분별 표시(differential display) RT-PCR, 노던 블롯 분석 및 다른 관련 시험에 의하여 이루어진다. 개별 PCR 반응을 사용하여 이들 기법을 수행하는 것이 가능하지만, mRNA로부터 생산된 사본 DNA (cDNA) 또는 사본 RNA (cRNA)를 증폭하고 마이크로어레이를 통하여 분석하는 것이 가장 좋다. 많은 어레이 구조 및 그의 제조방법이 당업자에게 알려져 있으며 하기와 같은 미국특허에 개시되어 있다: 5.445,934; 5,532,128; 5,556,752; 5,242,974; 5,384,261; 5,405,783; 5,412,087; 5,424,186; 5,429,807; 5,436,327; 5,472,672; 5,527,681; 5,529,756; 5,545,531; 5,554,501; 5,561,071; 5,571,639; 5,593,839; 5,599,695; 5,624,711; 5,658,734; 및 5,700,637; 상기 개시 내용은 참조에 의하여 본 명세서에 포함된다.
마이크로어레이 기술은 수천 개의 유전자의 정상상태 mRNA 수준을 동시에 측정할 수 있도록 하기 때문에, FTI가 세포 생물학에 미치는 영향과 그러한 영향의 분석에 근거한 치료의 예상 효과를 확인하기 위한 강력한 도구를 제공한다. 두가지의 마이크로어레이 기술이 현재 널리 사용되고 있다. 그 제1은 cDNA 어레이이고제2는 올리고뉴클레오티드 어레이이다. 이들 칩의 구성에는 차이가 존재하지만, 특히 모든 하류 데이터 분석 및 출력 결과(output)는 동일하다. 이들 분석의 산물은 일반적으로 상기 마이크로어레이 상의 알려진 위치(known location)에서 핵산 서열에 혼성화하는 시료로부터 cDNA 서열을 검출하기 위하여 사용되는 표지된 프로브로부터 얻어지는 신호의 강도를 측정한 결과이다. 일반적으로, 상기 신호의 강도는 cDNA의 양에 비례하고, 따라서, 시료 세포 중에서 발현된 mRNA에 비례한다. 많은 그러한 기술이 사용가능하고 유용하다. 유전자 발현을 결정하는 바람직한 방법은 참조에 의하여 그 개시 내용이 본 명세서에 포함되어지는, 하기 미국특허에서 찾을 수 있다: Linsley 등의 6,271,002; Friend 등의 6,218,122; Peck 등의 6,218,114; 및 Wang 등의 6,004,755.
발현 수준의 분석은 그러한 강도를 비교함으로써 이루어진다. 이는 대조군 시료 중에서의 유전자 발현에 대한 실험군 시료 중에서의 유전자 발현의 비율 행렬(matrix)을 생성시킴으로써 가장 잘 이루어진다. 예를 들면, 약물로 처리된 조직으로부터 생성된 유전자 발현 강도를 상기 약물로 처리되지 않은 동일한 조직으로부터 생성된 유전자 발현 강도와 비교할 수 있다. 이들 발현 강도의 비율은 상기 실험군과 대조군 시료 사이의 유전자 발현에 있어서의 배수-변화(fold-change)를 나타낸다.
유전자 발현 프로필은 또한 많은 방식으로 표시될 수 있다. 가장 흔한 방법은 열(column)은 실험군 시료를 나타내고, 행(row)은 유전자를 나타내는 그래픽 나무막대도형(dendogram)으로 비율 행렬(ratio matrix)를 배열하는 것이다. 비슷한발현 프로필을 갖는 유전자는 서로 가깝게 위치하도록 데이터를 배열한다(예, 도 1). 각 유전자에 대한 발현 비율은 색으로 가시화된다. 예를 들면, 1보다 작은 비율(하향조절(down-regulation)을 나타냄)은 스펙트럼의 파란색 부분으로 나타내고, 1보다 큰 비율(상향조절(up-regulation)을 나타냄)은 스펙트럼의 붉은색 부분의 색으로 나타낼 수 있다. Batelle의 "OMNIVIZ PRO" 소프트웨어와 Stanford의 "TREE VIEW" 소프트웨어를 포함한, 상업적으로 이용가능한 컴퓨터 소프트웨어 프로그램이 그러한 데이터를 표시하기 위하여 이용할 수 있다.
분별적으로(differentially) 발현되는 유전자는 FTI로 처리한 후, 질병 세포에서 상향 또는 하양 조절된다. 상향 조절 및 하향 조절은 상대적인 용어로서, 검출가능한 차이(차이를 측정하기 위하여 사용되는 시스템 내의 노이즈의 기여를 벗어나는 정도의 차이)가 기저선(baseline)에 대한 유전자의 발현 양에 있어서 발견된다는 것을 의미한다. 이 경우, 상기 기저선은 처리되지 않은 질병 세포에 대하여 측정된 유전자 발현양이다. 다음으로, 처리된 질병 세포 중에서의 유전자는 동일한 측정 방법을 사용한 상기 기저선 수준에 대하여 상대적으로 상향 또는 하향 조절된다. 바람직하게는, 상향 및 하향 조절의 수준은 혼성화된 마이크로어레이 프로브의 강도 측정결과의 배수 변화(fold change)에 근거하여 구별된다. 1.5 배 차이는 그러한 구별을 만들기에 바람직하다. 즉, 어떤 유전자가 처리된 질병 세포 대 처리되지 않은 질병 세포에서 분별적으로 발현된다고 하기 위하여는, 상기 처리된 세포는 상기 처리되지 않은 세포에 비하여 1.5 배 이상 또는 1.5배 보다 작은 강도를 생성시키는 것으로 밝혀져야 한다. 유전자 발현 측정 결과에 있어서 1.7배 차이가 더욱바람직하고, 2배 이상의 차이가 가장 바람직하다. 표 3은 모든 세포주에 걸쳐서 및 반응자 시료에 있어서 흔하게 조절되는 유전자를 목록화한 것이다.
유전자의 포토폴리오는 유전자의 집합(set)으로서, 상기 유전자의 집합에 대한 정보가 진단, 예후, 또는 치료 선택과 같은 임상 관련 판단을 하는데 근거를 제공하도록 분류된 것이다. 이 경우, 상기 포토폴리오에 의하여 지지되는 상기 판단은 FTI에 의한 백혈병 치료와 관련된다. 유전자 발현 프로필의 포토폴리오는 표 1-3에 나타낸 유전자의 조합을 포함할 수 있다.
본 발명의 한가지 방법은 다양한 유전자에 대한 유전자 발현 프로필을 비교하여 어떤 개체가 치료제의 사용에 반응할 것 같은지를 결정하는 단계를 포함한다. 반응자와 비반응자를 구별하는 상기 유전자 발현 프로필을 확립한 다음, 각각의 상기 유전자 발현 프로필은 하기하는 바와 같이 컴퓨터 판독가능한 매체와 같은 매체에 고정된다. (AML의 경우 조혈모세포(hematopoietic blast cell)와 같은) 질병 세포는 그를 포함하는 환자 시료를 얻은 다음, 그로부터 얻는다. 다음으로, 상기 질병 환자 세포로부터 시료 RNA를 얻어 증폭하고, 바람직하게는, 마이크로어레이를 통하여 적당한 포토폴리오 중의 유전자에 대한 유전자 발현 프로필을 얻는다. 다음으로, 시료의 상기 발현 포토폴리오를 반응자 및 비반응자로 이미 결정된 유전자 발현 프로필과 비교한다. 상기 시료 발현 패턴이 FTI 반응자 발현 패턴과 일관되면, (반대되는 의학적 소견이 없는 경우) FTI 치료를 표시할 수 있다. 상기 시료 발현 패턴이 FTI 비반응자 발현 패턴과 일관되면, FTI 치료를 표시되지 않을 수 있다. 바람직하게는, 발현 패턴의 일관성은 상기한 바와 같은 마이크로-어레이 판독상의 강도 측정 결과에 근거하여 결정된다.
비슷한 방식으로, 유전자 발현 프로필 분석은 치료 반응을 모니터링하기 위하여 수행될 수 있다. 이 방법의 일 태양에 있어서, 상기한 바와 같은 유전자 발현 분석은 치료 과정에 걸쳐 다양한 시기에서 FTI로 처리된 환자에 대하여 수행된다. 상기 유전자 발현 패턴이 FTI 반응자 발현 패턴과 일관되면, 환자의 치료법은 계속된다. 그렇지 않으면, 상기 환자의 치료법은 티로신 키나제 저해제와 같은 추가의 치료제와 함께 처리, 투여량의 변화, 또는 FTI 치료의 제거와 같은 치료법으로 변경된다. 그러한 분석에 의하여 검출가능한 임상적 지표가 나오기 전에, 또는 임상적 지표가 애매한 경우 개입(intervention) 및 치료법 조정을 할 수 있게 된다.
일부 유전자 발현 프로필이 어떤 관점에서는 반응자를 표시하는 것으로, 다은 관점에서는 비반응자를 표시하는 것으로 기록될 수 있는 애매한 결과가 얻어질 수도 있다. 예를 들면, 상기 포토폴리오는 3개의 유전자는 반응자와 일관되는 상향 조절된 것으로 나타날 수 있고, 다른 유전자는 반응자에 대하여 통상적인 바와 같이 상향-조절되지 않는 것으로 나타날 수 있다. 그러한 경우, 상기 환자가 상기 약물에 반응하거나 반응하지 않을 확률을 결정하기 위하여 통계적 알고리듬이 적용될 수 있다. 이 목적으로 적당한 통계적 알고리듬은 잘 알려져 있으며 이용가능하다.
본 발명의 물품(article)은 컴퓨터 판독가능한 매체(자기적, 광학적 등의)와 같은 자동적으로 판독될 수 있는 매체로 전환되고, 치료, 진단, 예후, 단계 결정(staging) 및 질병 검사에 유용한 상기 유전자 발현 프로필의 표현물(representation)이다. 상기 물품은 또한 그러한 매체 중의 상기 유전자 발현 프로필을 검사하기 위한 지침서를 포함할 수 있다. 예를 들면, 상기 물품은 상기한 유전자 포토폴리오의 유전자 발현 프로필을 비교하기 위한 컴퓨터 지침서를 갖는 CD ROM을 포함할 수 있다. 본 발명의 물품은 또한 환자 시료로부터 얻어진 유전자 발현 데이터와 비교될 수 있도록 매체 내에서 디지털로 기록된 유전자 발현 프로필을 가질 수 있다. 또한, 상기 프로필은 다른 표현적 형식(representational format)으로 기록될 수 있다. 그래프 기록이 그러한 양식 중 하나이다. 도 1은 그러한 기록 중 그래프 표시의 일예를 나타낸다. 상기한 "OMNIVIZ" 및 "TREE VIEW" 컴퓨터 프로그램에 포함되어 있는 것과 같은 클러스터링 알고리듬이 그러한 데이터의 가시화를 최적으로 도울 수 있다.
본 발명에 따른 추가의 물품은 본 발명의 상기 유전자 발현 프로필을 분간하는, 상기한 바와 같은, 핵산 어레이(예, cDNA 또는 올리고뉴클레오티드 어레이)이다.
(상기한 알고리듬을 포함한) 클러스터링 분석을 사용하여 특정한 통계적 신뢰도로 유전자간의 조절 관계를 확립하기 위하여 환자 시료의 상기 발현 수준을 비교할 수 있다. 그러한 발현 데이터에 근거하여 동적 지도(dynamic map)가 구축되었다. 그러한 유전적 네트워크 지도는 약물 발견에 유용하다. 예를 들면, 일단 관심을 갖는 기본 유전자가 확인되면, 그러한 유전적 네트워크 지도를 사용하여 잠재적 상류 조절 유전자의 목록을 찾는다. 다음으로, 그렇게 확인된 유전자 또는 그의 발현 산물을 약물 표적으로 사용할 수 있는지를 분석한다. 일부 구현예에서, 확인된 특정한 유전자의 상기 조절 기능은 백혈병 치료용 치료제를 확인하기 위하여 사용되었다.
전사, RNA 가공 및 RNA 편집의 조절은 그들 자신의 유전자에 의하여 코딩된 단백질에 의하여 모두 이루어진다. 더욱이, DNA 서열이 위치 효과(positional effect)에 의하여 다른 유전자의 발현에 대하여 원거리 조절을 할 수 있다. 그러므로, 유전자의 발현은 다른 유전자의 발현에 의하여 종종 조절된다. 그러한 조절 유전자(regulatory gene)를 조절되는 유전자 또는 하류 유전자에 대하여 상대적으로 상류 유전자라고 한다. 임의의 단순한 조절 경로에 있어서:
A++>B-->C++>D
여기서, A, B, C, D는 유전자이고, ++ 상향-조절하고, --는 하향-조절한다.
유전자 A는 유전자 B의 상류-유전자이고, B는 C의 상류-유전자이다. 당업자라면 상기 네트워크는 종종 루프화되어 있고 상호연결되어 있다는 것을 이해할 것이다. 일부의 경우, 유전자의 발현은 양성 또는 음성 피드백으로서 자기 자신의 산물에 의하여 조절된다.
클러스터 분석 방법은 발현 수준이 연관되어 있는 유전자를 분류하기 위하여 사용되었다. 클러스터 분석 방법은 참조에 의하여 어떠한 목적상으로도 본 명세서에 포함되어지는, Harfigan (1975) Clustering Algorithms, NY, John Wile and Sons, Inc, 및 Everritt, (1980) Cluster Analysis 2nd. Ed. London Heineman Educational books, Ltd.에 상세하게 기재되어 있다. 경로 분석은 변수들 간의 관계를 분해하고 상기 유전적 네트워크에 대한 원인 모델(causal model)을 시험하기 위하여 사용된다. 백혈병 세포에 있어서 약물의 복수 개의 일차 표적이 확인될 뿐만 아니라, 그러한 세포의 치료에 유용한 약물/약물 부류가 확인되었다. 본 발명에 따르면, 약물은 생물학적 시스템을 동요시키는 임의의 정도의 복잡성을 가진 임의의 화합물이다.
상기 약물의 생물학적 효과는 1종이상의 RNA의 전사 또는 분해 속도, 1이상의 폴리펩티드의 번역 또는 번역후 가공의 속도 또는 정도, 1이상의 단백질의 분해의 속도 또는 정도, 1이상의 단백질의 작용 또는 활성의 자극 또는 저해 등에 있어서의 약물-매개된 변화의 결과일 수 있다. 바람직한 FTI에 더하여, 본 발명의 바람직한 약물은 MAPK/ERK 신호전달 경로, TGFβ, WNT 또는 세포자가사 경로를 조절하는 것들이다. 이들 약물에는, 티로신 키나제 저해제, MEK 키나제 저해제, PI3K 키나제 저해제, MAP 키나제 저해제, 세포자가사 조절인자 및 그들의 조합이 포함되나, 여기에 한정되는 것은 아니다. 이들 중 가장 가장 바람직한 예시적 약물은 노바티스사의 "GLEEVEC" 티로신 키나제 저해제, U-0126 MAP 키나제 저해제, PD-098059 MAP 키나제 저해제, SB-203580 MAP 키나제 저해제, 및 안티센스, 리보자임 및 DNAzyme Bcl XL 항-세포자가사 약물(anti-apoptotics)이다. 다른 유용한 약물의 예에는, 미국특허 6,306,897의 칼라놀리드(calanolide); 6,284,764의 치환된 비시클릭크스(bicyclics); 6,133,305의 인돌린(indolines); 및 6,271,210의 안티센스 올리고뉴클레오티드가 포함되나, 여기에 한정되는 것은 아니다.
상기한 바와 같이, 본 발명의 약물은 유전자 치료 또는 안티센스 치료를 지향하는 치료제일 수 있다. mRNA 번역을 차단하기 위하여 mRNA 서열에 상보적인 서열을 갖는 올리고뉴클레오티드가 세포내로 도입되어, 상기 mRNA를 코딩하는 상기유전자의 기능을 차단할 수 있다. 유전자 발현을 차단하기 위하여 올리고뉴클레오티드를 사용한 예는 예를 들면, 참조에 의하여 본 명세서에 포함되어지는, Strachan and Read, Human Molecular Genetics, 1996에 기재되어 있다.
이들 안티센스 분자는 DNA, 포스포로티오에이트 또는 메틸포스포네이트와 같은 안정한 DNA 유도체, RNA, 2'-O-알킬RNA와 같은 안정한 RNA 유도체 또는 다른 안티센스 올리고뉴클레오티드 모사체(mimetics)일 수 있다. 안티센스 분자는 미세주입, 리포좀 포집화 또는 상기 안티센스 서열을 갖는 벡터로부터의 발현에 의하여 세포내로 도입될 수 있다.
유전자 치료의 경우, 상기 유전자는 수용체 숙주 세포의 감염에 의하여 치료용 DNA의 전달을 매개하는 바이러스 벡터에 연결될 수 있다. 적당한 바이러스 벡터에는 레트로바이러스, 아데노바이러스, 아데노-연관 바이러스, 헤르페스 바이러스, 폴리오 바이러스 등이 포함된다. 또한, 치료용 DNA는 리간드-DNA 접합체 또는 아데노바이러스-리간드-DNA 접합체를 사용한 수용체 매개 표적화된 DNA 전달, 리포펙션(lipofection) 막 융합 또는 직접적 미세주입을 포함한, 비바이러스성 기법에 의하여 유전자 치료용 세포내로 도입될 수 있다. 이들 과정 및 그의 변이된 과정은 인비보(in vivo) 유전자 치료 뿐만 아니라, 엑스 비보(ex vivo) 유전자 치료에 적합하다. 상기 유전자와 함께 사용하기에 적합한 유전자 치료의 분자 방법론에 관한 지침(protocol)은 Gene Therapy Protocols, edited by Paul D. Robbins, Human press, Totawa NJ, 1996에 개시되어 있다.
본 발명의 약물을 포함하는 약제학적으로 유용한 조성물은 약제학적으로 허용가능한 담체의 혼합물(admixture)에 의하는 것과 같은 알려진 방법에 따라 제제화될 수 있다. 그러한 담체 및 제제화 방법의 예는 Remington's Pharmaceutical Sciences에서 찾을 수 있다. 효과적인 투여에 적합한 약제학적으로 허용가능한 조성물을 형성하기 위하여는, 그러한 조성물은 효과적인 양의 상기 약물을 포함할 것이다. 상기 약물의 효과적인 양은 개체의 조건, 체중, 성별 및 나이와 같은 다양한 인자에 따라 달라질 수 있다. 다른 인자에는 투여의 방법이 포함된다. 상기 약제학적 조성물은 피하, 국부(topical), 경구 및 근육내와 같은 다양한 경로에 의하여 상기 개체에 제공될 수 있다.
본 발명의 상기 약물은 상기 약물의 기본 분자의 화학적 유도체를 포함한다. 즉, 일반적으로는 상기 기본 분자의 일부분이 아닌 추가의 화학적 부위를 포함할 수 있다. 그러한 부위는 기본 분자의 용해도, 반감기, 흡수 등을 개선시킬 수 있다. 또한, 상기 부위는 상기 기본 분자의 바람직하지 않은 부작용을 감소시키거나 상기 기본 분자의 독성을 감소시킬 수 있다. 그러한 부위의 예는 Remington's Pharmaceutical Sciences와 같은 다양한 문헌에 기재되어 있다.
본 명세서에 기재된 방법에 따라 확인된 화합물은 임의의 잠재적 독성을 최소화하면서, 최적 저해 또는 활성을 얻기 위하여 통상의 시험에 의하여 정의된 적절한 투여량으로 단독으로 사용될 수 있다. 더욱이, 다른 약제의 공동-투여 또는 순차적 투여가 바람직할 수도 있다.
본 발명의 약물은 투여를 위한 종래의 운반체(vehicle) 중에서 아주 다양한 치료적 투여 형태(dosage form)로 투여될 수 있다. 예를 들면, 상기 약물은 정제,캡슐제(각각 시간조절(timed) 방출 및 지속방출 제제를 포함함), 알약, 분말, 과립, 엑릭서(elixir), 팅크제, 용액, 현탁액, 시럽 및 유화액과 같은 경구 투여 형태로 투여될 수 있고, 또는 주사제에 의하여 투여될 수 있다. 비슷하게, 상기 약물은 또한 약제 업계의 당업자에게 모두 잘 알려진 행태를 사용하여, 정맥내(볼루스 및 주입 모두), 복강내, 피하, 폐색을 포함하거나 포함하지 않는 국부, 또는 근육내 형태로 투여될 수 있다. 원하는 화합물의 효과적이나 비독성적인 양이 조절 약제로서 채용될 수 있다.
상기 산물의 일별 투여량은 1일, 환자당 0.01 내지 1,000mg의 광범위에 걸처 변할 수 있다. 경우 투여에 대하여, 상기 조성물은 바람직하게는, 치료될 환자에 대하여 상기 투여량의 증상적 조정(symptomatic adjustment)를 위하여 활성 성분으로 0.01, 0.05, 0.1, 0.5, 1.0, 2.5, 5.0, 10.0, 15.0, 25.0, 및 50.0 mg을 포함하는 스코어된 또는 스코어되지 않은 정제의 형태로 제공되는 것이다. 상기 약물의 효과적인 양은 1일 약 0.0001mg/kg 체중 내지 100mg/kg 체중의 투여량 수준으로 통상 제공된다. 상기 범위는 더욱 구체적으로는, 1일 약 0.001mg/kg 체중 내지 10mg/kg 체중이다. 상기 투여량은 원하는 효과를 얻기 위하여 조합되어지는 경우 조정된다. 한편, 이들 다양한 약제의 투여량은 독립적으로 최적화되거나, 어느 하나의 약제가 단독으로 사용될 때 보다 병의 상태(pathology)가 더 감소되는 상승적 효과를 얻기 위하여 조합될 수 있다.
유익하게, 본 발명에 사용되는 화합물 또는 조절약제(modulator)는 단일 일일 용량(daily dose)으로 투여되거나, 총 일일 투여량(daily dosage)이 1일 2, 3또는 4회로 나눠진 용량으로 투여될 수 있다. 더욱이, 본 발명에 사용되는 화합물 또는 조절약제는 당업자에게 잘 알려진 적당한 비강내 운반체의 국부적 사용을 통한 비강내 형태로 투여되거나, 경피 피부 패치의 경피 형태를 사용하여 경피 경로를 통하여 투여될 수 있다. 경피 시스템의 형태로 투여되기 위하여는, 상기 투여량 투여는 물론, 상기 투여량 요법에 걸쳐서 간헐적인 것 보다는 당연히 연속적인 것이다.
2이상의 활성 약제로 조합 치료하기 위하여, 상기 활성 약제가 별도의 투여량 제제화(dosage formulation)로 되어 있는 경우, 상기 활성 약제는 동시에 투여되거나, 또는 각각이 별도로 번갈아 가면서 투여될 수 있다.
본 발명의 화합물 또는 조절약제를 사용하는 투여 계획(regimen)은 환자의 형태(type), 종, 나이, 체중, 성별 및 의약적 상태; 치료될 상태의 경중; 투여 경로; 환자의 신장 및 간장 기능; 및 사용될 특정한 약물을 포함한 다양한 인자에 따라 결정된다. 통상의 의사 또는 수의사이면 질병 상태의 진행을 예방, 반전 및 정지시키기 위하여 필요한 약물의 효과적인 양을 쉽게 결정하여 처방할 수 있다. 독성이 없이 효능을 나타내는 범위 내에서 약물의 농도를 얻는 최적의 정확도는 표적 부위에서 약물의 이용가능성의 속도론(kinetics)에 근거한 요법(regimen)을 필요로 한다. 이는 약물의 분포, 평형 및 제거를 고려하는 것과 관련된다.
본 발명의 약물은 활성 성분을 형성할 수 있고, 일반적으로 의도하는 투여 형태, 즉, 경구 정제, 캡슐, 엘릭서(elixir), 시럽 등에 관하여 적당하게 선택되고 종래의 약제학적 실시와 일관되는, 적당한 약제학 희석제(diluent), 부형제 또는담체(본 명세서에서는 집합적으로 "담체(carrier)" 물질이라 한다)와의 혼합물로 보통 투여된다.
예를 들면, 정제 또는 캡슐의 형태로 경구 투여되는 경우, 상기 활성 약물 성분은 에탄올, 글리세롤, 물 등과 같은 경구, 비독성 약제학적으로 허용가능한 불활성 담체와 조합되어질 수 있다. 더욱이, 바람직하거나 필요한 경우, 적당한 결합제(binder), 윤활제, 붕해제 및 착색제가 또한 상기 혼합물에 포함되어질 수 있다. 적당한 결합제에는 녹말, 젤라틴, 포도당 또는 베타-갈락토오즈, 옥수수 감미제, 아카시아, 트라가칸트 또는 소듐 알지네이트와 같은 천연 및 합성 검, 카르복시메틸셀룰로즈, 폴리에틸렌글리콜, 왁스 등을 포함하나, 여기에 한정되는 것은 아니다. 이들 투여량 형태에 사용되는 윤활제(lubricant)는 소듐 올레에이트(sodium oleate), 소듐 스테아레이트, 마그네슘 스테아레이트, 소듐 벤조에이트, 소듐 아세테이트, 소듐 클로라이드 등이 포함되나, 이들에 한정되는 것은 아니다. 붕해제에는 녹말, 메틸셀룰로즈, 한천, 벤토나이트, 잔탄검 등이 포함되나, 여기에 한정되는 것은 아니다.
액체 형태에 대하여, 상기 활성 약물 성분은 예를 들면, 트라가칸트, 아카시아, 메틸-셀룰로즈 등과 같은 합성 및 천연 검과 같은 적당하게 풍미가 가미된 현탁화 또는 분산제와 조합되어질 수 있다. 사용될 수 있는 다른 분산제에는 글리세린 등이 포함된다. 비경구 투여에 대하여, 멸균 현탁액 및 용액이 바람직하다. 정맥내 투여가 바람직한 경우, 일반적으로 적당한 보존제를 포함하는, 등장물(isotonic preparation)이 사용된다.
본 발명의 약물은 또한 작은 단일 라메라 소포체, 큰 단일 라멜라 소포체 및 다수 라멜라 소포체와 같은 리포좀 전달 시스템의 형태로 투여될 수 있다. 리포좀은 콜레스테롤, 스테아릴아민, 또는 포스파티딜콜린과 같은, 다양한 인지질로부터 형성될 수 있다.
본 발명의 약물은 상기 화합물 분자가 결합되는 개별 담체로서 단일클론 항체의 사용에 의하여 또한 전달될 수 있다. 본 발명의 약물은 또한 표적화가능한(targetable) 약물 담체로서 용해가능한 중합체와 결합되어질 수 있다. 그러한 중합체는 폴리비닐-피롤리돈, 피란 공중합체, 폴리히드록시프로필메타크릴-아미드페놀, 폴리히드록시-에틸아스파타이미드페놀, 또는 팔미토일 잔기로 치환된 폴리에틸-엔옥시드폴리라이신(polyethyl-eneoxidepolylysine)를 포함할 수 있다. 더욱이, 본 발명의 약물은 약물의 제어된 방출(controlled release)이 이루어지도록 하는데 유용한 생분해성 중합체의 일 부류, 예를 들면, 폴리락틱산, 폴리엡실론 카프로락톤, 폴리히드록시 부티르산, 폴리오르토에스테르, 폴리아세탈, 폴리디히드로-피란, 폴리시아노아크릴레이트 및 히드로젤의 가교된 또는 양쪽성 블록 공중합체에 결합되어질 수 있다.
경구 투여에 대하여, 상기 약물은 캡슐 또는 볼루스 형태로 투여될 수 있으며, 또한 음식물과 혼합물될 수 있다. 상기 캡슐, 정제 및 볼루스는 녹말, 탈크, 마그네슘 스테아레이트, 또는 디칼슘 포스페이트과 같은 적당한 담체 운반체와 조합된 활성 성분으로 이루어진다. 이들 단위 투여량 형태는 활성 성분을 희석제, 필러, 붕해제 및/또는 결합제를 포함하는 적당하게 미세-분말화된 불활성 성분과 균일한 혼합물이 얻어지도록 치밀하게 혼합함으로써 제조된다. 불활성 성분은 상기 약물과 결합하지 않고, 치료될 동물에 비독성적인 성분이다. 적당한 불활성 성분은 녹말, 락토즈, 탈크, 마그네슘 스테아레이트, 식물 검 및 오일 등이 포함된다. 이들 제제는 치료될 동물 종의 크기 및 형태(type) 및 감염의 경중과 같은 많은 인자에 따라 아주 다양한 양의 활성 및 불활성 성분을 포함할 수 있다. 상기 활성 성분은 또한 상기 화합물을 사료와 단순히 혼합함으로써 또는 상기 화합물을 사료의 표면에 적용함으로써 또한 투여될 수 있다.
상기 화합물 또는 조절제는 또한 불활성 액체 담체에 용해된 활성 성분으로 구성되는 제제의 주사를 통하여 비경구적으로 투여될 수 있다. 상기 주사는 근육내, 반추위내, 기관내, 또는 피하에 될 수 있다. 상기 주사가능한 제제는 적당한 불활성 액체 담체와 혼합된 상기 활성 성분으로 구성된다. 허용가능한 액체 담체에는 땅콩 기름, 면화씨 기름, 참깨 기름 등과 같은 식물유 뿐만 아니라, 졸케탈(solketal), 글리세롤 포말(glycerol formal) 등과 같은 유기 용매가 포함된다. 대안으로서, 수성 비경구 제제가 또한 사용될 수 있다. 상기 식물유가 바람직한 액체 담체이다. 상기 제제는 최종 제제가 상기 활성 성분 0.005 중량% 내지 1O% 중량 %를 포함하도록 상기 액체 담체 중에 용해 또는 현탁화시킴으로써 제조된다.
본 발명을 하기 비한정적인 실시예를 통하여 보다 상세하게 설명한다.
실시예 1: 세포 배양
AML-유사 세포주 HL-60 (전골수구성(promyelocytic)) 및 U-937 (전단핵세포성(promonocytic))를 ATCC로부터 얻었다. AML-193 (단핵세포성(monocytic)) 및 THP-I (단핵세포성(monocytic)) 세포는 샌디에고 소재의 RW Johnson Pharmaceutical Research Center로부터 얻었다. 세포를 20% 우태아혈청(FBS)로 보충된 로즈웰 파크 메모리얼 연구소(Roswell Park Memorial Institute)(RPMI) 배지에서 생장시켰다. AML-193은 또한 과립세포-대식세포집락-자극인자 (GM-CSF) (10 ng/ml), 인슐린 (0.005 mg/ml), 및 트란스페린 (0.005 mg/ml)으로 보충되었다.
실시예 2 : 독성 용량 분석
상기 실시예1의 세포를 1 x 105cell/ml의 초기 농도로 6-웰 플레이트에 접종하였다. (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)를 DMSO 3㎕ 중의 0.5 내지 500nM의 농도 범위로 상기 배양 배지에 직접적으로 첨가하였다. 실시예1로부터 얻은 대조군 세포를 배지에서 단독으로 생장시키거나 운반체(O.1% DMSO)로 보충된 배지에서 생육시켰다. 세포수는 4일 및 7일째에 헤마사이토미터로 계수하였고, 세포 생존성은 트리판 블루배제 분석법에 의하여 결정하였다. IC50는 7일째에 처리된 시료에서의 살아 있는 세포의 수가 대조군 시료에서의 세포 수의 50%인 용량(dose)으로서 정의된다. 계산은 반복 실험한 값에 근거하여 수행되었다. 4개 세포주의 IC50을 FTI 처리 후 7일째에 계산하였다. AML-193은 IC50가 134 nM이고, BL-60은 IC50가 24 nM이고, THP-1은 IC50가 19 nM이고, U-937은 IC50가 44nM이다. 이는 4개의 AML-유사 세포주가 FTI 치료에 민감하다는 것을 나타낸다.
실시예 3 : 경과 분석
실시예1의 세포의 2반복 배양액(duplicate culture)를 1x105cell/ml의 초기 농도로 6-웰 플레이트에 접종하였다. (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)를 DMSO 3㎕ 중의 100nM의 농도로 상기 배양 배지에 직접적으로 보충하였다. 100nM의 농도는 부분적으로 실시예 2의 결과에 근거한 치료 과정(protoccol)을 노말라이즈하기 위한 후속 경과(time course) 실험을 위하여 선택되었다. 2반복(duplicate) 대조군 배양물을 O.1% DMSO를 포함하는 배지에서 생육시켰다. 2 반복 배양물은 총 6일 동안 매일 회수하였다. 세포를 계수하고, 생존성을 분석하고, 총 RNA를 제조업자의 지침서(Qiagen RNeasy)에 따라 분리하였다. 분석 결과에 의하면, 다른 세포주로부터 유래한 세포는 다른 시기에 영향을 받는다는 것이 나타났다. RNA는 잔존 게놈 DNA를 제거하기 위하여 DNase 1 (Qiagen DNase 1 kit)으로 처리하였다. RNA의 선형증폭(linear amplification)이 Van Gelder의 미국특허 제5,545,533호에 개시된 과정에 따라서 수행되었다. RNA 5㎍ 분액을 cDNA 어레이 상에서의 혼성화용으로 제조하였다.
실시예4 : 골수 처리
골수 흡입물(aspirate)은 FTI로 처리된 AML로 진단된 2명의 환자로부터 얻었다. 이들 환자에 21일에 걸처서 1일 2회 600mg의 (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)을 투여하였다. 골수 흡입물은 기저선과 3주간의 처리 기간동안 일주일에 1회 취하여졌다. 이들 환자 중 한 사람은 반응하지 않았으나(RH), 다른 한 사람은 FTI에 반응하였다(BS). 반응은 골수 흡입물에서 모세포(blast cell)의 50%이상의 감소로서 결정되었다. 상기 흡입물을 PBS로 15ml로 희석하고, 피콜(Ficoll)-밀도 원심분리하였다. 백혈구를 PBS로 2회 세척하고, 10% DMSO를 갖는 FBS에 재부유하고, 곧바로 -80℃에서 냉동하였다. 세포를 세포 생존성을 유지하기 위하여 냉동 보존하였다. 시료를 37℃에서 해동하고, 20% FBS로 보충된 10X 부피의 RPMI를 5분에 걸쳐 점적하였다. 세포를 1600rpm에서 10분 동안 원심분리하고, 2 mM EDTA 및 0.5% BSA로 보충된 PBS 10ml에 현탁화하였다. 다음으로, 시료를 70μM 필터를 통과시켜 세포 덩어리(clump)를 제거하였다. 세포 생존성을 트리판 블루 분석법으로 결정하였다. 시료 생존성이 50%보다 작으면, Miltenyi Dead Cell Removal Kit를 사용하여 살아 있는 세포 분획을 풍부하게 하였다. 다음으로, 2xlO5의 살아 있는 세포를CD33-FITC과 CD34-PE 항체 (Pharminigen)로 이중 표지하고, FACS 분석을 수행하였다. (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)-처리 후 골수 시료를 CD33 또는 CD34 항체(Miltenyi)를 사용한 자기 비드 세포 분리에 의하여 백혈병 세포에 대하여 풍부하게 되었다. 상기 추출된 세포로부터 실시예3에 개시한 바와 같이 RNA를 추출하였다.
실시예 5 : 프로브 제조
실시예 3 및 4에서 얻어진 RNA 시료를 하기 과정에 따라 cDNA 마이크로어레이에 혼성화하기 위한 준비를 하였다. 출발 물질의 양에 따라 총 RNA에 대하여 1 내지 2회의 선형 증폭을 수행하였다. 먼저, 1-10㎍의 총 RNA를 Superscript cDNA transcription kit (Gibco BRL)를 사용하여 역전사하였다. 먼저, 10㎕의 총 RNA를 0.5 mg/ml T7-oligodT 프라이머 1㎕와 혼합하고, 70℃에서 1O 분 동안 배양한 다음, 얼음에서 식혔다. 다음으로, 8㎕의 5X 제1 가닥 반응 버퍼, 0.1 M DTT, 10 mM dNTPs, 및 1㎕ RNase Block을 첨가하고, 상기 용액을 42℃에서 5 분 동안 배양하였다. 다음으로, 1㎕의 Superscript II를 첨가하고, 상기 반응물을 42℃에서 2시간 동안 배양하였다. 상기 반응물을 70℃에서 10 분 동안 열불활성화시키고, PCR용으로 1㎕를 제거하였다. 다음으로, 92㎕ 무-RNase 물, 30 ㎕ 5X 제2-가닥 반응 버퍼, 3㎕ 1OmM dNTP, 4㎕ DNA polymerase 1, 1㎕E.coliRNase H, 1 ㎕E.coliDNA ligase를 첨가하고, 상기 혼합물을 16℃에서 2시간 동안 배양하였다. cDNA를 Ampliscribe T7-transcription kit (Epicenter)를 사용하여 선형 증폭하였다. 필요하다면, 랜덤 헥사머 접근법(random hexamer approach)에 의하여 제2회의 RNA 증폭을 수행하였다. 랜덤 헥서머를 갖는 RNA로 프라밍하고 뉴클레오티드 믹스 중에 Cy3-dCTP를 포함시킴으로써, 형광으로 표지된 cDNA 프로브를 합성하였다. 반응물은 QIAquick PCR purification kit (Qiagen)를 사용하여 정제하고, 프로브의 부피는 상대적 형광(Cytofluor)을 사용하여 노말라이즈하고, 50% 포름아미드 및 인간 Cot1 DNA(Life Technologies)로 보충된 버전 2 혼성화 버퍼(Amersham Pharmacia Biotech, Pistcataway, NJ) 50㎕ 중에 현탁화하였다.
실시예 6 : 어레이 혼성화 및 분석
상기 어레이는 IMAGE 컨소시움(Integrated Molecular Analysis of Genome and their Expression: Research Genetics, Huntsville, AL) 및 Incyte libraries로부터 얻은 7452 cDNA를 포함한다. 마이크로-어레이는 하기와 같이 제조되었고, 프로브는 실시예5에 기재된 바와 같이 혼성화되었다. cDNA는 Generation III Micro-array Spotter (Molecular Dynamics)를 사용하여 아미노 실란-코팅된 슬라이드(Corning) 상에 프린트되었다. 상기 cDNA는 PCR 증폭되고, 정제되고(Qiagen PCR purification kit), 10 M NaSCN 프린팅 버퍼와 1:1로 혼합되었다. 혼성화하기 전에 마이크로-어레이를 실온에서 10분 동안 이소프로판올에서 배양하였다. 상기 프로브를 95℃에서 2분 동안, 실온에서 5분 동안 배양한 다음, 3개의 사본(replicate) 슬라이드에 적용하였다. 커버 슬립을 DPX (Fluka)로 슬라이드 상에 밀봉하고 42℃에서 밤새 배양하였다. 다음으로, 슬라이드를 1X SSC/0.2% SDS 및 0.1X SSC/0.2% SDS에서 55℃에서 5분 동안 세척하고, 0.1X SSC에서 담그고 건조하여 GenIII Array Scanner (Molecular Dynamics)로 스캔하였다. 각 스팟에 대한 형광 강도를AUTOGENE 소프트웨어 (Biodiscovery, 로스앤젤레스)로 분석하였다.
발현 수준의 75번째 백분위수(percentile)가 마이크로-어레이에 걸처서 동일하도록 각 마이크로-어레이의 강도 수준을 노말라이즈하였다. 분산 계수(CV)가 평균의 50%보다 큰 값을 나타내는 클론을 분석으로부터 제외하였다. 배경 강도가 모든 실험에 대하여 최대 32 단위이었기 때문에, 이 보다 낮은 발현 수준을 보이는 모든 클론에 문턱치 32를 할당하였다. 다음으로, 처리된 시료와 대조군 시료의 쌍(pair-wise) 분석에 근거하여 비율 행렬을 생성하고, 유클리드 미터법(euclidean metric) 및 평균 연관법 (Omniviz ProTM)을 사용하여 계측적 클러스터링을 수행하였다.
각 시료를 3개의 동일 어레이에 혼성화하고, 평균 신호 강도를 스캐터-플롯(scatter-plot) 분석에 의하여 비교하였다. 대조군 시료를 동일자의 처리된 시료와 비교하였을 때, 높은 상관계수를 또한 관찰하였다. 이는 (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)으로 처리로 인한 유전자 발현의 순 변화는 없다는 것을 나타낸다. 더욱이, 다른 날의 대조군 시료사이의 변이를 검사하였다. 세포를 가짜로 처리하고(mock-treated), RNA를 1, 2, 3, 4, 5, 및 6 일후 분리하였다. 표지 및 혼성화 후, 2반복 시료의 평균 강도 및 각 클론(클론 당 3 스팟)의 분산계수(CV)를 계산하였다. 50%보다 큰 CV를 보이는 데이터 포인트는 추후 분석에서 제외하였다.
실시예 7 :처리된 세포주 시료에서 분별적 유전자 발현
OmniViz ProTM소프트웨어 (Battelle)를 사용하여 시간경과(time-course) 데이터 세트에 대하여 계층적 클러스터링을 수행하였다. 먼저, 시간경과의 각 일별에 대한 처리군과 대조군 강도 비율에 대하여 1.5, 1.7 및 2.0의 배수-변화를 필터로서 사용하였다. 이들 문턱치를 초과하여 조절되는 유전자의 상기 유전자 발현 프로필을 분석하여 3개 데이터 세트 사이에서 공통으로 조절되는 유전자를 검사하고 유사한 발현 프로필을 공유하는 유전자 클러스터를 확인하였다. 그 결과를 하기 표 1-3에 나타내었다.
본 발명에 따라서 분석된 유전자는 유전자 ID 번호(내부적으로 생성하였다) 및 유전자 젠뱅크(Genbank) 데이터베이스에 등록된 젠뱅크 데이터베이스의 등록번호(accession number)의 참조에 의하여 하기 표에서 확인된다. 참조에 의하여 본 명세서에 포함되어지는, 첨부된 서열 목록은 유전자 ID 번호에 해당하는 서열을 나타내고, 그 유전자 ID 번호로 명명된다. 일부 경우에 있어서, 목록화된 서열은 단백질 또는 펩티드의 산물을 코딩하는 전장 핵산 서열에 관한 것이다. 당업자라면 분석적 관점에서라면 전장 서열의 확인은 필요하지 않다는 것을 알 것이다. 즉, 프로브가 해당 유전자에 대하여 유전자 발현을 검사하기 위하여 디자인될 수 있다는 잘 알려진 원리에 따라, 서열의 일부분 또는 EST가 선택될 수 있다. 더욱이, 상기 목록의 일부 서열은 뉴클레오티드 표시 대신에 문자 "N"을 포함한다. 당업자라면 "N"은 상기 서열의 부분에서 임의의 뉴클레오티드가 위치함을 나타내다는 것을 알 것이다.
실시예 8 : 유전자 네트워크의 확인
약물 처리된 세포주에서 1.5배 이상으로 2이상의 세포주에서 조절되는 유전자(표 1)를 상기한 바와 같이 확인하였다. 이들 유전자의 목록을 사용하여 가장 바람직한 FTI, (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)에 의하여 조절되는 주요한 유전자 경로를 확인하였다. 클론이 완벽하게 매치되지 않는 경우, 상기 클론 서열의 최적 BLAST 결과로부터 얻어지는 알려진 유전자 주석(annotation)을 사용하였다. 이들 유전자의 조절 수준은 상기 세포주의 치료 과정에 걸처서 변하기 때문에, 이 FTI에 반응한 일차 AML 조직으로부터 상기 유전자 발현 프로필을 결정하였다.
MAPK/ERK (도 2) 신호전달 경로의 많은 유전자가 하향-조절되고, TGFβ (도 3) 및 WNT (도 3) 신호전달 경로의 유전자가 일반적으로 상향-조절되고, 세포자가사 경로는 또한 활성화(도 4)된다는 것이 밝혀졌다. 이에 의하여 알려진 또는 신규한 약물 화합물의 처리에 민감한 다른 유전자 표적을 확인할 수 있게 되었다. 예를 들면, 더 강력한 효과를 얻기 위하여 FTI를 티로신 키나제, MEK 키나제, PI3K 및/또는 MAP 키나제 저해제와 함께 사용함으로써 이로운 치료를 초래할 수 있다. 더욱이, 세포자가사 경로가 FTI 처리된 세포에서 활성화된다는 사실에 비추어 보면, 세포자가사를 조절하는 약물은 FTI와 함께 사용되는 경우, 이로운 효과를 낼 수 있다는 것을 예측할 수 있다. 이러한 형태의 화합물의 예에는 티로신 키나제 저해제(예, Gleevec, 노바티스), MAP 키나제 저해제(예 U-0126, PD-098059, SB-203580), 및 Bcl-XL (예, 안티센스, 리보자임, DNAzymes)과 같은 항-자가세포사 유전자의 저해제가 포함된다.
표 1 : 6일 시간 경과에 걸처서 2이상의 세포주에서 1.5배 이상으로 조절되는 유전자(젠뱅크 등록번호로 표시).
유전자 ID 등록 번호
3434105F7 AB026898
3881595H1 AC000134
AI939481 AC005155
AA961061 AC005670
3918104H1 AC006023
AI025519 AC008427
554336OF8 AC009220
AA744682 AC009289
AA932129 AC009756
AI148008 ACO11473
Y00052 AC013722
R52476 AC021078
AA864819 AC022087
AI815593 AC022150
AI141943 AC026448
AI300541 AC073585
2515486H1 AF161372
1731618H1 AJO03147
BE222911 AJ400879
R13802 AK022901
AI656222 AL021155
AI553823 AL022313
AA010251 AL034397
AA237071 AL035420
2445101F6 AL049824
AI638342 AL122004
AA779424 AL136980
H81171 AL137073
R77754 AL137790
AI209040 AL139082
6421806H1 AL139396
H61066 AL161787
R59209 AL355136
AA486141 AL355352
AI339252 AP001630
AW023438 BC009732
914979H1 BC013834
AA455969 D00015
T64335 D00017
X02308 D00596
X67098 D00596
X01023 D10493
D10493 D10493
Y00396 D10493
X69292 D10667
AA736561 D11094
S68252 D11139
M25315 D12592
AI186110 D13118
H84153 D13639
AA598561 D14043
D14695 D14695
2206642T6 D16889
AI878943 D17004
U38846 D17080
J03801 D21235
AI762926 D23660
D25215 D25215
U41078 D26512
AA485961 D30648
AA456408 D38441
AI311090 D38616
1869911H1 D42084
D43950 D43950
AW006368 D44467
U29092 D45050
D45887 D45887
W68193 D49489
3633286H1 D63874
N76967 D66904
AA985407 D82326
AI962797 D83260
M59829 D85730
3107995H1 D86322
AA279906 D86550
AI016874 D86586
556963H1 D86955
AI810687 D86997
AF045581 D87462
U41070 D89078
D90209 D90209
AA812265 D90767
2135769H1 J02763
1876511H1 J03072
J04088 J04088
AI590075 J04973
H30357 J05451
K00558 K03460
L10413 L00634
L01087 L01087
AI027898 L02426
L06139 L06139
U28936 L07914
M86400 L07955
AA428915 L08634
AA464627 L09604
M94859 L10284
R78541 L10717
L15189 L11066
L11284 L11284
T87908 L12387
T80827 L13802
L08044 L15203
AI278029 L16862
M60278 L17032
M60278 L17032
M65128 L18980
W49672 L20861
L22005 L22005
AI380522 L23822
AA988469 L25591
L26336 L26336
AI074564 L32866
M63175 L35233
2470939H1 L35848
AA19O648 L36055
AI243166 L38716
L39833 L39833
M97347 L41415
2005142H1 L42324
M11723 L43615
U04045 L47574
AA284067 L76938
M13142 M13142
W68291 M15395
5560880H1 M19483
3171275H1 M20199
M22489 M22489
AA070627 M22810
H39560 M24736
M25897 M25897
M27492 M27492
AA570304 M29366
205581R6 M29696
M84739 M32294
M84739 M32294
M35857 M32315
3801801H1 M33680
M63904 M63904
AI091579 M63971
M69215 M69215
M74782 M74782
M80254 M80254
M80647 M80647
M84526 M84526
6805226H1 M84526
S93414 M86553
M91556 M91556
M95678 M95678
2017923F6 M96326
H73054 NM_000551
AA488324 NM_001211
N73242 NM_001274
AF013611 NM_001335
AW163686 NM_0O1524
AI921879 NM_002287
AI652785 NM_002333
AI423526 NM_003332
3028719F6 NM_003600
ABO10882 NM_003601
AF030424 NM_003642
AW194791 NM_003668
AF075599 NM_003969
AF031141 NM_004223
2676931T6 NM_004412
AF053304 NM_004725
AF119815 NM_004885
AI816398 NM_004888
2185556H1 NM_004917
3357511Hl NM_004917
AA047585 NM_005109
AA448972 NM_005592
AW629084 NM_005817
AJO01015 NM_005854
AJO01016 NM_005856
U85055 NM_006480
3618886F6 NM_006536
AA906714 NM_006573
AF060153 NM_007037
1467864F6 NM_012089
AI097079 NM_012100
AF204944 NM_012105
W44673 NM_012428
AI522316 NM_013386
AI700673 NM_013439
AA057781 NM_014172
AI299795 NM_014251
1931159F6 NM_014397
AW630208 NM_014413
2821685T6 NM_014967
1539060H1 NM_015343
AI762738 NM_015449
AA401397 NM_015596
AW243944 NM_015596
AI436551 NM_016141
AI651159 NM_016440
AA527334 NM_016625
g922698 NM_017555
1693028H1 NM_017636
002783H1 NM_017860
AI368583 NM_017874
AW170305 NM_017903
H62827 NM_018321
M78706 NM_019020
BE048230 NM_020216
AI214466 NM_020334
AA452802 NM_021196
AI808824 NM_022082
W77977 NM_022336
AA535015 NM_022570
AA861140 NM_022829
AW078834 NM_023080
5122087H1 NM_024056
AF017182 NM_024101
AA449040 NM_024116
2792728F6 NM_024902
BE218593 NM_025230
AA669885 NM_030763
AI339565 NM_030908
AF038564 NM_031483
AI126706 NM_032038
1961084H1 NM_O32188
460981OF6 NM_032554
AA745592 NM_032844
AW612141 NM_033050
AI740538 NM_033280
U58522 S51O16
M57703 S63697
AA873257 S73591
AA521213 S77359
N77754 S79873
AA984230 S80071
R79935 S81439
T71391 T71391
AA598776 U05340
U11053 U11053
T55353 U12597
AA456616 U14970
U18300 U18300
AF017306 U20657
AA459663 U25182
U27699 U27699
AI884916 U29171
U29171 U29171
1671033F6 U33429
AA017042 U40989
AI126520 U48405
U48807 U48807
U49395 U49395
AA186542 U50078
U51586 U51586
AW150605 U54558
AA455800 U55206
AF029777 U57316
I19355 U58913
319095H1 U58913
AF027964 U59911
U60519 U60519
AI371158 U65378
U69883 U9883
H30148 U73641
R80718 U75283
U77180 U77180
U78180 U78180
U83115 U83115
AA938905 U86218
AI401546 U88844
2526681H1 U90904
AA773114 U95740
AA176596 U96781
X13274 V00543
I16618 V00595
R91899 X00226
AW519155 X00318
X87344 X00369
X02910 X01394
M15840 X02532
AA401046 X02592
X02812 X02812
X87344 X03066
X03084 X03084
M10901 X03225
X03225 X03225
R81823 X03742
X04011 X04011
K02400 X04076
X07036 X04408
X07036 X04408
Y00816 X05309
N20475 X05344
Ml1233 X05344
X02544 X05784
X52192 X06292
R33755 X06547
X06989 X06989
X07979 X07979
X14723 X08004
M20566 X12830
M20566 X12830
X13197 X13197
M21304 X13709
X00351 X13839
X60236 X14008
H57180 X14034
M33011 X14758
X14768 X14768
M31625 X14768
M31626 X14768
M30816 X14768
X52882 X14983
AA598758 X15187
X15606 X15606
K03515 X16539
AA868186 X17093
X51416 X51416
M23699 X51439
AA455222 X51675
X51757 X51757
X52195 X52195
U06434 X53682
J03198 X54048
M32304 X54533
AA487812 X56134
X56134 X56134
M16985 X56257
N31660 X56257
H27379 X57198
X57522 X57522
X57830 X57830
M57765 X58377
X58528 X58528
M81182 X58528
S60489 X60111
AI739095 X61157
R76314 X61587
M83665 X62534
X65921 X65921
M37722 X66945
AA453816 X69516
AA187162 X69654
X69819 X69711
X70070 X70070
X70697 X70697
S40706 X71427
T53775 X71874
X71877 X71877
X73458 X73468
X74801 X74801
AA454585 X75755
R43734 X76939
AI189206 X77303
2496221H1 X77303
H17504 X80692
R26434 X80910
X83688 X83688
U24231 X84709
3576337H1 X85030
X87212 X87212
T56477 X87212
AA464034 X89401
X89576 X89576
AA187458 X92396
M15887 X94565
X94991 X94991
X96427 X96427
X97058 X97058
AA425120 X98262
3283686H1 XM_005825
AW027188 XM_005958
1525902F6 XM_006646
R48796 XM_008099
AK000599 XM_027140
AA044653 XM_031608
AW665954 XM_O35574
H86407 XM_037453
R00285 XM_038150
X57447 XM_039395
778372H1 XM_040459
R82530 XM_041024
AI580830 XM_042041
3097063H1 XM_044784
3038910H1 XM_046691
H53340 XM_O48213
165421OF6 XM_048530
L42856 XM_054964
270727OF6 XM_056259
M23468 Y06062
Y00649 Y00649
Y00757 Y00757
Ml7017 Y00787
M28130 Y00787
L02932 Y07619
Y10256 Y10256
AA454813 Y12395
AA149850 Y12670
704183H1 Y13710
059476H1 Y13829
Y13834 Y13834
L11016 Y14768
3141315H1 Y17803
AI341167 Y18391
AI707852 Z12962
U51278 Z23115
AI686653 Z26876
AA043102 Z35102
AA136533 Z35481
U49083 Z49148
R70234 Z56852
257274R6 Z58168
U62027 Z73157
391237F1 Z73157
510997F1 Z73157
AI808621 Z82214
AA460801 Z98749
2673259F6 Z98752
R22977 Z98946
L03380 Z99995
AA425422
AA460392
AA508510
AA552028
AA576785
AA663307
AI015248
AI024468
AI086865
AI190605
AI203269
AI264420
AI333013
AI435052
AI671268
AI796718
AI990816
AW027164
AW167520
H24679
H66015
H91370
W07570
1274737F6
195337H1
2398102H1
2531082H1
264639H1
2794246F6
3290073H1
335737H1
4539942F8
6300669H1
938765H1
표 2: 일차 AML 시료에서 1.7 배 이상으로 조절되는 유전자(젠뱅크 등록 번호로 표시)
유전자 ID 등록번호
T94331 ABO26898
3881595H1 AC000134
1329021F6 AC002073
2858615H1 AC002325
AI791539 AC002428
AI821217 AC004258
AA774798 AC004671
H20666 AC004845
T95173 AC005071
AA814523 AC005160
590562OT9 AC005212
5986963H1 AC005280
5825251H1 AC005306
N36113 AC005670
1700438H1 AC005682
R48756 AC005757
5538589F6 AC005839
3918104H1 AC006023
AA443719 AC007240
AI867297 AC007883
R63067 AC008073
AW022174 AC008382
5537789F6 AC008525
H00249 AC008733
143624OH1 AC008860
2668191F6 AC008949
554336OF8 AC009220
AA737674 AC009892
5104579H1 AC009892
3335217F6 AC010311
BE326380 AC010521
3746214H1 AC011088
1671315F6 AC011500
H60969 AC012351
AA926944 AC012377
3100089H1 AC012454
Y00052 AC013722
R52476 AC021078
N45149 AC021106
AI742120 AC022137
4177228F6 AC022224
2676312H1 AC022415
H73476 AC022740
AA652121 AC046170
AI308320 AC046170
1956982H1 AC046170
1428534F6 AC051619
2914934H1 AC055707
AA621370 AC064807
5514511R6 AC073333
AI698737 AC074331
3406131H1 AC079118
N20072 AC096579
5911413H1 AC096667
AI458182 AF042782
2291436H1 AF074333
W32067 AF136745
6755801J1 AF157623
2397317F6 AF235100
R53190 AF384819
1731618H1 AJO03147
2959801H1 AJO03147
3123232H1 AJO03147
276011OH1 AJO06345
X64073 AJ239325
3986782F7 AJ249275
AI366098 AJ276674
AI695385 AJ289236
BE222911 AJ400879
AI400473 AK017738
AI299633 AK021499
R13802 AK022901
1489075H1 AK025775
AI656222 AL021155
W96144 AL021155
245954OH1 AL031282
3461693F6 AL031588
4333034Hl AL031726
3332309H1 AL031728
R61661 AL032821
U71321 AL033519
AA935151 AL034374
AA010251 AL034397
U43431 AL035367
AA237071 AL035420
AA609779 AL049610
AA167461 AL049612
4228729H2 AL049742
6712339H1 AL049766
AI051176 AL049872
1747028Hl AL078600
5164454H1 AL109840
7007735Hl AL117382
AA526337 AL121601
AI638342 AL122004
4835576H1 AL122035
W01596 AL133243
U64205 AL133367
4820983H1 AL135786
5594552Hl AL136381
H12102 AL136979
H81171 AL137073
AA151374 AL137790
AA578089 AL138787
AI209040 AL139082
6421806H1 AL139396
H60498 AL157776
3721604Hl AL160271
H61066 AL161787
2798009Hl AL162252
2225447F6 AL162430
AI885557 AL162729
2918417F6 AL163279
AA489975 AL355151
U77456 AL355794
5375277T9 AL356266
AI051860 AL356489
4019605F6 AL356489
U29607 AL356801
AA861429 AL359512
AA767859 AL359915
1362587H1 AL391122
R09122 AL391194
R93094 AP000173
AA954331 AP000432
R10535 AP000555
5327443Hl AP000936
1569726Hl AP001347
R92422 AP001672
3422674H1 AP002800
AI310451 AP002812
3568042H1 AP003900
AA455969 D00015
AF030575 D00015
T64335 D00017
D12614 D00102
X67098 D00596
R27585 D00759
AA465593 D00762
M80436 D10202
M80436 D10202
M80436 D10202
M80436 D10202
AA464600 D10493
AI147046 D10653
S68252 D11139
M25315 D12592
AI186110 D13118
S57708 D13515
D13626 D13626
AA682625 D13641
AA598561 D14043
D14695 D14695
D14825 D14825
855326R1 D16234
L20046 D16305
V00496 D17206
AA629808 D17554
M57285 D21214
J03801 D21235
AI700360 D21878
D25216 D25216
U41078 D26512
AF245447 D28468
AF245447 D28468
AA070997 D29012
2134847H1 D30756
AI147295 D30756
AA455067 D31839
AI311090 D38616
AW629690 D42084
18699llHl D42084
5122374Hl D43701
D43950 D43950
D45887 D45887
W68193 D49489
X72498 D50326
L11667 D63861
D63874 D63874
3633286Hl D63874
X61598 D83174
AA279906 D86550
AA729988 D86550
D86956 D86956
L36719 D87116
D89078 D89078
U41070 D89078
AI821897 D89675
D90209 D90209
2135769H1 J02763
J03040 J03040
18765llHl J03072
J03258 J03258
J03571 J03571
J04111 J04111
AI125073 J04132
1634342Hl J04794
H30357 J05451
K02054 K02054
X02415 K02569
K03000 K03000
H58873 K03195
AI791949 K03474
L10413 L00634
H22919 L03558
L04288 L04288
AA405769 L05144
H62473 L07594
L08177 L08177
L08177 L08177
AA234897 L08895
AA464627 L09604
M94859 L10284
R78541 L10717
L15189 L11066
M15400 L11910
L12168 L12168
L12350 L12350
L12350 L12350
T87908 L12387
L09600 L13974
M14221 L16510
M60278 L17032
M60278 L17032
M60278 L17032
M60278 L17032
2745317H1 L17411
M65128 L18980
W49672 L20861
AI380522 L23822
AA988469 L25591
NM_001168 L26245
R20939 L31848
2470939H1 L35848
AA442810 L36034
L36148 L36148
Ml1723 L43615
M14745 M14745
W68291 M15395
M16038 M16038
339598H1 M16038
M17783 M17783
3171275H1 M20199
5189380H1 M21121
4130807F7 M22440
M22612 M22612
AA070627 M22810
1445982H1 M23254
M28638 M24906
R45525 M28215
AI051962 M28983
736837R6 M29696
M29870 M29870
AI264247 M30309
1512407F6 M30310
M30471 M30471
M30704 M30703
AW467649 M31158
M84739 M32294
M84739 M32294
U52165 M32315
M35857 M32315
5077322H1 M32315
N72918 M34175
M63193 M58602
M59465 M59465
2294719H1 M60858
2992331H1 M63005
AA069596 M63582
M63904 M63904
AI091579 M63971
M74782 M74782
AA410680 M77016
M80647 M80647
M84526 M84526
S93414 M86653
AI310138 M91463
M95678 M95678
2017923F6 M96326
R60624 NM_000702
AA488324 NM_001211
AA488341 NM_001336
AF006823 NM002246
13223O5T6 NM_002250
AI921879 NM_002287
AW129770 NM_002349
AJO04977 NM-002873
AI423526 NM-003332
4516963H1 NM_003576
3028719F6 NM_003600
ABO10882 NM_003601
AF030424 NM_O03642
AF029899 NM_003814
AF055993 NM_003864
AI220935 NM_004142
AW665782 NM_004142
AI191941 NM_004226
1392516T6 NM_004621
AA449579 NM_004769
1810447H1 NM_004917
AA047585 NM_005109
4181072F6 NM_005468
AA448972 NM_005592
AA742351 NM_005739
3406436F6 NM_005845
AJO01015 NM_005854
311853OH1 NM_005880
AA906714 NM_006573
AI016020 NM_006672
AW770551 NM_006770
AW009940 NM_006871
864164H1 NM_007194
1467864F6 NM_012089
AF204944 NM_012105
W23427 NM_012115
3363678H2 NM_012226
AI652076 NM_012243
346874T6 NM_013308
AI522316 NM_013386
AI338030 NM_013439
AI700673 NM_013439
4540025H1 NM_O14322
W00842 NM_014331
AW511388 NM_014358
AW630208 NM-014413
H63640 NM_014834
AI743175 NM_014959
2821685T6 NM_014967
W38474 NM_015542
AW243944 NM_015596
W07181 NM_O15701
2997457H1 NM_015938
AA631149 NM_016205
AA527334 NM_016625
5543749F6 NM_017414
AW170305 NM_017903
AA160974 NM_018155
AA625433 NM_018404
AA074666 NM_018834
767295H1 NM_018983
M78706 NM_0l9020
AF245447 NM_020126
AF245447 NM_020126
4294821H1 NM_020344
2490994H1 NM_021624
3556218H1 NM_O21634
2435705R6 NM_022048
3092423H1 NM_022054
W77977 NM_022336
AA429219 NM_023930
1001514R6 NM_024022
AI031531 NM_024083
AA449040 NM_024116
2803571H1 NM_024586
139013OH1 NM_024671
3241088H1 NM_024850
H96170 NM_030779
1540906H1 NM_030779
AI824146 NM_030811
W90438 NM_032127
AA430653 NM_032177
3495438F6 NM_032294
AW612141 NM_033050
AA417237 NM_033225
AI740538 NM_033280
M57703 S63697
780099H1 S63912
AA714835 S67156
AA777347 S76736
AA521213 S77359
U39231 S79852
N77754 S79873
AA984230 S80071
U00672 U00672
U02478 U02478
AA019459 U02680
3401107H1 U03019
AI580044 U04816
3041874H1 U07563
2457652H1 U12465
U39318 U13175
U13666 U13666
U13695 U13695
AA056652 U14176
AA456616 U14970
U18242 U18242
U18300 U18300
AA465444 U18422
U20537 U20536
U25128 U25128
U35237 U26174
AI884916 U29171
AA481076 U31278
NM_002411 U33147
167lO33F6 U33429
AA664389 U35048
6313632H1 U43030
R09288 U43522
AA488645 U47007
U47077 U47077
5801413H1 U48449
2405358R6 U48729
AA186542 U50078
U51586 U51586
135514OF1 U51586
AA455800 U55206
U56390 U56390
U83410 U58088
AA121261 U58675
AF027964 U59911
U60519 U60519
2836805T6 U62293
U62433 U62433
3188135H1 U66673
3188135H1 U66673
3188135H1 U66673
3188135H1 U66673
1360938T6 U66679
809631T6 U66684
AA454652 U67058
AI214335 U68755
U69883 U69883
R98589 U81375
5695322H1 U82671
AA745989 U82979
AA188256 U83661
2526581H1 U90904
AA434064 U95000
AA773114 U95740
AA514978 U96776
Y07503 V00510
X96754 V00557
N67917 V01512
V01514 V01514
X87344 X00369
N53169 X00567
X02910 X01394
X01451 X01451
X01451 X01451
X01451 X01451
X01451 X01451
AA401046 X02592
5537736F6 X02592
X87344 X03066
M10901 X03225
M54894 X04403
M54894 X04403
M54894 X04403
M54894 X04403
X07036 X04408
X07036 X04408
N75719 X04744
M19507 X04876
Y00816 X05309
M11233 X05344
AA479102 X05972
N24824 X06182
R33755 X06547
N41062 X06820
M86511 X06882
X07549 X07549
1686702Hl X07730
X07979 X07979
X14723 X08004
J03561 X12510
J03561 Xl2510
J03561 X12510
J03561 X12510
M20566 X12830
M20566 X12830
M20566 X12830
M20566 X12830
U76549 X12882
M21304 X13709
X00351 X13839
X14830 X14830
X52882 X14983
AA598758 X15187
H27564 X15729
W15277 X15940
AA393214 X15949
M23502 X16166
K03515 X16539
M28880 X16609
2403512Hl X16674
AA868186 X17093
J03236 X51345
X51416 X51416
AA411440 X51521
AA058828 X51602
AA455222 X51675
X51804 X51804
T72877 X52015
X52195 X52195
X52947 X52947
U06434 X53682
3081284F6 X53702
M36821 X53799
AA490256 X54048
J03198 X54048
M60761 X54228
M11025 X55283
M33294 X55313
M33294 X65313
M31627 X55543
X55544 X55544
AA487812 X56134
X56134 X56134
X56777 X56777
H27379 X57198
M83652 X57748
X58528 X58528
M81182 X58528
S60489 X60111
X60592 X60592
R76314 X61587
M83665 X62534
R11490 X62947
AI436567 X63422
X63465 X63465
AA083577 X63527
X63547 X63546
215936OH1 X63692
X64074 X63926
X63926 X63926
X64083 X63926
2535659H1 X69168
AA87162 X69654
X69819 X69711
AI310990 X71491
T53775 X71874
3285272H1 X73568
U11087 X75299
X75299 X75299
AA454585 X75755
X75821 X75821
X75918 X75918
X76029 X76029
R43734 X76939
AI189206 X77303
H17504 X80692
R26434 X80910
AI521155 X81892
AA088861 X83228
U10440 X84849
407169Hl X84909
3576337Hl X85030
T55802 X85117
4407508H1 X85337
AA025432 X85373
T56477 X87212
AA464034 X89401
X89576 X89576
X89576 X89576
R83270 X89750
917064Hl X91249
X91809 X91809
X92106 X92106
AA187458 X92396
AJO00519 X92962
X94991 X94991
X96427 X96427
R85213 X98022
X98296 X98296
X99585 X99585
R48796 XM_008099
R50354 XM_009915
W15172 XM_016514
AK000599 XM_027140
7157414H1 XM_031246
AA044653 XM_031608
L16953 XM_032556
1266202T6 XM_033674
AA805691 XM_033788
AA861582 XM_036492
H86407 XM_037453
778372Hl XM_040459
AA016239 XM_041087
AI580830 XM_042041
AI732875 XM_042637
AA463411 XM_045320
AA648280 XM_O46411
303891OH1 XM_046691
H63831 XM_047328
165421OF6 XM_048530
AA460131 XM_049228
553962OF6 XM_049755
AA682896 XM_050250
L42856 XM_054964
1483347Hl XM_056259
AI307255 XM_O58135
H74265 Y00062
Y00064 Y00064
M17017 Y00787
M28130 Y00787
L02932 Y07619
AA504415 Y09781
AI809036 Y12336
AA516206 Y12851
000527Hl Y13829
059476Hl Y13829
Y13834 Y13834
L11016 Y14768
3141315H1 Y17803
551234R6 Y17803
AA426103 Y18000
H97778 Z13009
AA402431 Z15005
L07555 Z22576
U51278 Z23115
M58525 Z26491
AW772610 Z26652
Z29090 Z29090
H19371 Z32684
AA136533 Z35481
Z48810 Z48810
U49083 Z49148
R70234 Z56852
4902714H1 Z69918
150224T6 Z80147
M29871 Z82188
AI808621 Z82214
AA699919 Z83821
5538394Hl Z83843
5020377F9 Z97832
AA460801 Z98749
AI625585 Z98750
2673259F6 Z98752
R22977 Z98946
AA007596
AA188574
AA280754
AA283874
AA460392
AA508510
AA515469
AA526772
AA576785
AA634241
AA663307
AA663482
AA713864
AA714520
AA828809
AA868502
AI061445
AI086865
AI264420
AI378131
AI440504
AI567491
AI693066
AI709066
AI766478
AI821337
AI949694
AW439329
AW630054
H24679
H29257
H51856
H66015
H72339
N57580
N54592
W07570
T75463
R88730
R91509
T56441
T77711
W92423
1274737F6
1338107F6
1508571F6
1548205H1
1594182F6
1594701F6
1879290H1
1902928Hl
19437OH1
195337Hl
198381H1
2021568Hl
205203T6
2194064H1
224922R6
2398102Hl
2531082Hl
2630745F6
264639H1
2704982Hl
2716787Hl
279881OF6
2832401H1
2894096F6
2919406F6
2937644F6
2950021H1
3010621F6
3123948Hl
3253054R6
3290073Hl
3330472Hl
335737Hl
3674358H1
3749346F6
3820429H1
3978404F6
4031124H1
4056384H1
409706OH1
4288779H1
4301823H1
4558488F6
4570377H1
5058893F9
5541621H1
5546249F6
5546336H1
5771839H1
5804485H1
5849807H1
6530555H1
656258H1
6591535H1
869993H1
930273R6
938765H1
표 3 : 모든 세포주에서 1.5 배 이상으로 및 반응자 환자 시료에서 1.7 배 이상으로 조절되는 유전자(젠뱅크 등록번호로).
유전자 ID 등록번호
5543360F8 AC009220
AA237071 AL035420
AA455969 D00015
M25315 D12592
U41078 D26512
L10413 L00634
AA464627 L09604
2470939H1 L35848
M84526 M84526
AI921879 NM_002287
AF204944 NM_012105
W77977 NM_022336
AA449040 NM_024116
AA521213 S77359
AA984230 S80071
AA456616 U14970
AI884916 U29171
U60519 U60519
X00351 X13839
AA868186 X17093
H27379 X57198
AA454585 X75755
X89576 X89576
AI580830 XM_042041
U49083 Z49148
2398102H1
2531082H1
<110> Ortho-Clinical Diagnostics, Inc. <120> Methods For Assessing and Treating Leukemia <130> CDS 293 PCT <140> PCT/US 02/34784 <141> 2002-10-30 <150> 60/340,938 <151> 2001-10-30 <150> 60/338,997 <151> 2001-10-30 <150> 60/340,081 <151> 2001-10-30 <150> 60/341,012 <151> 2001-10-30 <160> 900 <170> PatentIn version 3.1 <210> 1 <211> 376 <212> DNA <213> HUMAN <400> 1 ctgtttaatt atctgtaata atccttaaaa atcagcacac aaatccattc caggtagctt 60 ttgcaaccca actgctgtgg tggcaattgt ccagatgcca caacccccta agagtgggtc 120 atcctggggg agcaaggcct gagaaaggaa aggaagggaa aggcccccta gtgcctgccc 180 cacagccctg aggaaggcac atatttagcc tggcctgaga caggacagga aggggccaca 240 gggctgaagt gcagggacaa aggggtcagg gtcccaagtg tccggggccc cagctaccca 300 ccccatgtct gtttttggtt ttgtcattaa aaaaaataaa gtgacaatac tggtggagac 360 cagttgttgc actgtc 376 <210> 2 <211> 500 <212> DNA <213> HUMAN <400> 2 gattggtaac ctaatttgtg gcctcctgac ttttaaggaa aacgtgtgca gccattacac 60 acagcctaaa gctgtcaaga gattgactcg gcattgcctt cattccttaa aattaaaaac 120 ctacaaaagt tggtgtaaat ttgtatatgt tatttacctt cagatctaaa tggtaatctg 180 aacccaaatt tgtataaaga cttttcaggt gaaaagactt gattttttga aaggattgtt 240 tatcaaacac aattctaatc tcttctctta tgtatttttg tgcactaggc gcagttgtgt 300 agcagttgag taatgctggt tagctgttaa ggtggcgtgt tgcagtgcag agtgcttggc 360 tgtttcctgt tttctcccga ttgctcctgt gtaaagatgc cttgtcgtgc agaaacaaat 420 ggctgtccag tttattaaaa tgcctgacaa ctgcacttcc agtcacccgg gccttgcata 480 taaataacgg agcatacagt 500 <210> 3 <211> 276 <212> DNA <213> HUMAN <400> 3 taagttgtaa aaaaaatttt gttatttata aatgaattac acaataaaat aattattttt 60 aaaagtcaca aatacaatcg ttgtataaag tcattttggc atcaagtatc tcttaaatat 120 gttgcaaact attttccaaa gagatgtggt ccaaaccctc tgaaggcttt ataattttgt 180 attagataac aagtgaacaa aactgacaat aaatactcca acaattattt tttaaaatac 240 taagtggcaa atgctattct aagtggcaaa acaatc 276 <210> 4 <211> 444 <212> DNA <213> HUMAN <400> 4 tatcaacatt tatatgcttt attgaaagtt gacaagtgca acagttaaat acagtgacac 60 cttacaattg tgtagagaac atgcacagaa acatatgcat ataactacta tacaggtgat 120 atgcagaaac ccctactggg aaatccattt cattagttag aactgagcat ttttcaaagt 180 attcaaccag ctcaattgaa agacttcagt gaacaaggat ttacttcagc gtattcagca 240 gctagatttc agattacaca aagtgagtaa ctgtgccaaa ttcttaaaat ttctttaggt 300 gtggtttttg tcatgtagca gtttttatgt agatctatat ataaaagtcc acacctcctc 360 agacagccaa tgaaacaact aaatttcaat ctgtacaacc taaatagtag ttacagtcct 420 ctattgtaca aaatagttac acta 444 <210> 5 <211> 381 <212> DNA <213> HUMAN <400> 5 aggctacata ctgccaacaa ccatgtgtct ctctagtcca cctcctgccc ctgagatccg 60 gactcacatc cgattgcctc tttaatctct ccgtttgaat gcccaacagg catctcaaaa 120 acacttcccc catggcctcc cagtttcccc catggtaaga aacagcccac cggctactct 180 gttcgagtca cactctcaga cagatttctc ctttctgtcc atcatctctt ccccacctct 240 gtctctaaag tatatcacag cttcgtgccc cagcacctag cacagcacat ggcaagcttc 300 ccgtaaatgt gtgctgagtc acctctggag gtcacctgct aatgagggag gtctctcctg 360 gcacaggtca cttaggaaag g 381 <210> 6 <211> 518 <212> DNA <213> HUMAN <400> 6 tttttttttt tcatcttaac aacctttaat agttatctaa atgcagagtt tgtttatgaa 60 atgaaccaaa gcagtttgtc atttcttact ataaaatatt gaaaatcaag tgcgaaactc 120 agccactatt ggctaaagaa actaaataaa aaacgttaat gacctagaaa agcaaaagcc 180 cattttaaac tacttaaagc ctctgcacta gtccaatgag tcaaaggcaa gggagaagta 240 aacctctaaa actgaagacg accctctaaa ggagaaaact atagaagtta aagtatgcat 300 gcttattata ctatgggaaa ccaggaagga agggagagaa aaagaaaaag cacagtctat 360 tcatccaggg caatcagtaa aaatctacag taacctgatc aaccacaaaa tccttaggtg 420 ttgtgaaatt acattggtca cttctgtaat cctaaaactt aaaatgattg gtctctttaa 480 aataaatggt ttcaaaataa taggatggtc ccattaaa 518 <210> 7 <211> 380 <212> DNA <213> HUMAN <400> 7 tttatttggg atctttttta tttttataca catgacaaga ttttacatca agaatagtca 60 gttaaatagt acaaatttac attcatgagg aatgttaaag aaaattcaac taaaaaaccc 120 actttttcct gtgacccata atcccacatt ttacagtgca ggggagaagg ggattagggg 180 gcatccaaaa caagtctctc ccaaaaagaa atgatgtaaa tttcacattc cctctccaca 240 caggatccaa atggtgagag tataatttac aattcatctt tttcagctgt agattccttt 300 gctgtttctt cttcttcatc tgttcccaca tccatttctg catcttcgtc ttgctctgtg 360 tcttctgttg tgtcttctgc 380 <210> 8 <211> 469 <212> DNA <213> HUMAN <400> 8 aaaaaaaaaa catgaaggga gacatgactt tattagaaaa ataaaaaaca actgaggtga 60 tgggttggtc ttcagcggat ccttggtgga tgaggctgct tttggctgca ctggccttct 120 cccgctcccg ccgccgcgca gggtccaact caaaacagcg ccatagcctc agggtctcat 180 ctgctgctgc ggatgccact gtggccccat ctgggctcat ggtcagactc aggacccggg 240 atgtgtgacc tttgagttca gccaccttgg ccatggttgg gtacttccaa ataactagct 300 gattctgtgc aaagccatgg cctgagatga gctccttgta agggggagac cagaggatgg 360 agcacacctg ggaatgggca tccacggcac tcagacaggc cccagagcaa aaattccaga 420 tgcgaatgtg tcgatcactg gtgcaccctc ctgtggcaag gacatttga 469 <210> 9 <211> 335 <212> DNA <213> HUMAN <400> 9 caacgagaag gtggagctgc aggagctgaa tgaccgcttc gccaactaca tcgacaaggt 60 gcgcttcctg gagcagcaga ataagatcct gctggccgag ctcgagcagc tcaagggcca 120 aggcaagtcg cgcctggggg acctctacga ggaggagatg cgggactgcg ccggcagtgg 180 accagctaac caacgacaaa gcccgcgtcg aggtggagcg cgacaacctg gccgaggaca 240 tcatgcgcct ccgggagaaa ttgcaggagg agatgcttca gagagaggaa gccgaaaaca 300 ccctgcaatc tttcagacag gatgttgaca atgcg 335 <210> 10 <211> 518 <212> DNA <213> HUMAN <400> 10 aagtcaccta taaatatact tacagaacca ccaagtcaaa atgtggagaa agagatgaat 60 tatccccaaa gagaattaaa gtggaggatg ggtttccaga tttccaggat tctgtgcaaa 120 cactcttcca gcaggctaga gctaagagtg aagaacttgc agctcttagt tcacagcagc 180 ctgaaaaggt gatggcaaag cagatggagt tcctttgcaa ccaagctggc tatgagagac 240 tgcagcatgc cgagaggagg ttgtctgcag ggctttacag gcagagctca gaagagcaca 300 gtcctaacgg cttgacttcc gataactcag atggacaagg agaaagacct ttgaatctcc 360 gaatgcctaa tttacagaac agacaacccc atcattttgt ggtggatggg gagctgagca 420 gactttaccc cagtgaggca aagtcccact catcagagag ccttgggatt ttaaaagact 480 accctcattc agcttttacc ttagaaaaga aagtcatc 518 <210> 11 <211> 460 <212> DNA <213> HUMAN <400> 11 tttttatttt tttttttttt tctttactca ccattttaat actgccgcca actataacag 60 attaaaaatg tacacatgac aaagtggaaa aaagtcccaa aatgcaacag tttcagcaaa 120 agaacatact ggctaaggat tactacagtt aacatcggta cagtaaaaac gatggcaaac 180 agggatttgg caccacattt acaaagtaaa agcatgcact gttaatacac tttagatgtt 240 tctcaacaga aaaggccatg aagatggaaa acaagaggca ccatgtacaa aactccctat 300 aactgggaca aacaagcaag aatcaaagtg gtcaatttag taaatatgta gcagcaaagt 360 cactggttct gtttggaatt tagcaatttg catttctgat tggcagctgc cctgggtgtg 420 tctgtatcca agaagctgac tttatccaac tacatcagca 460 <210> 12 <211> 493 <212> DNA <213> HUMAN <400> 12 tttttttttt ttgcatatat taattcagtt taatcatatc aattcttaaa caaaaaactt 60 cctccaagag acaatagttc acagtaactg caaagcttac tcacaatttt taaaaatatc 120 gctcatgctt agcattcaaa gaagatatta tagaataact gtaaaaactt ttaccaggaa 180 catcagcttc tgacttgaaa aattacaaat actgaagcat tttggtatca gacacagtag 240 ttttgacatt gtctgttcat ttgatgagtt tctggaagtt tggaaaattg tacctctata 300 attggataat gcgcttattc taaactaaac attttcaaat gtagaaaaca aactagcaag 360 ctacacatac aaagaaaagc cctctaagat ttgcttttca catgttgaat gccagcatgt 420 gcaccgtgaa tcctggaaga ctagaattga tacatacgct tggcttgaag tctatacccc 480 aggctcacga tgg 493 <210> 13 <211> 428 <212> DNA <213> HUMAN <400> 13 tttttttaaa acaaacttaa ctttatttcc tcactttcac ttaaaacttg attttataaa 60 acacatgaaa aaacattttt aagagttctg tatcacagaa cattaaacag tacaaatatc 120 cattgcttca taggttcaag ttacataaat taaagtcaaa taattggaaa ctgattcaat 180 agggaaaact atacatgaaa tgaaggtcaa aaggagctat acagcaatat ttcattgttt 240 atagattatg agttactttc aggaccttaa caaagattct gaatatttag acttcctttg 300 ttgtatttta tacttaaata tctccctacc tatactgagt caaactactt gaccaaaaca 360 tctgatttag gaaagcatct agctttatag cacaagtttt tccatctaca gttactatct 420 tcaaagga 428 <210> 14 <211> 473 <212> DNA <213> HUMAN <400> 14 gcactgtgtg ttcagtgaaa actagagaaa cacaataagc aaatcacatg aaggctgaga 60 tgattgagat gaaagttaac atagtgtgaa tgaaagtctg gccaacagag cagtagatga 120 tataacaaag aaagcatgct ttctgaggag atagtgggga taatccctga agagttggca 180 gtgtgagtgc actcatttat cttctgtgag gtgggatttt tgtgttcctc acacccatgt 240 aattattctt agaattgaga ttgctacacg gagcagtcct tgacgatcgt gtttctgacg 300 tttctcttcc ttgcctggac tgcctttgac aaggcagaaa tgaacatgaa aagtccccag 360 gagaggggag ctgtgtagtg agggatactg agggcagtcc tgtggctgag gggcacagat 420 tgaactgctg aactagttgg aggtctagat gaggtgcttt acgcatcagc tgc 473 <210> 15 <211> 411 <212> DNA <213> HUMAN <400> 15 cgatgactca atcggcactg ggtatgacct gtcagcctct acattctctc ctgacggaag 60 agtttttcaa gttgaatatg ctatgaaggc tgtggaaaat agtagtacag ctattggaat 120 cagatgcaaa gatggtgttg tctttggggt agaaaaatta gtcctttcta aactttatga 180 agaaggttcc aacaaaagac tttttaatgt tgatcggcat gttggaatgg cagtagcagg 240 tttgttggca gatgctcgtt ctttagcaga catagcaaga gaagaagctt ccaacttcag 300 atctaacttt ggctacaaca ttccactaaa acatcttgca gacagagtgg ccatgtatgt 360 gcatgcatat acactctaca gtgctgttag accttttggg ctgcagtttc a 411 <210> 16 <211> 287 <212> DNA <213> HUMAN <400> 16 gccggagagt ctacaatgtt acccagcatg ctgttggcat tgttgtaaac aaacaagtta 60 agggcaagat tcttgccaag agaattaatg tgcgtattga gcacattaag cactctaaga 120 gccgagatag cttcctgaaa cgtgtgaagg aaaatgatca gaaaaagaaa gaagccaaag 180 agaaaggtac ctgggttcaa ctaaagcgcc acgctgctcc acccagagaa gcacactttg 240 tgagaaccaa tgggaaggag cctgagctgc tggaacctat tccctat 287 <210> 17 <211> 473 <212> DNA <213> HUMAN <400> 17 tttcaatgat atatttgcca gttattttat tttttctaaa aacaatagaa aaaaatcaac 60 tttaaaaagc aaaatgtact taaataaaaa aaattagggt ttatagtacc tataatacta 120 ggtactatat actaggattg aaattctgtg taactgctat aaacgtttta ttaaagttat 180 ttacatttaa tggcaatatt tacagagaaa cattgtgtaa atcttaaaat tttttaaaaa 240 caattcttaa atacaaatct gttaaagaaa aaaaaaagat ggtaagcata aaaaagttct 300 tttatgccca aagtccaatt tgaggcagtt tacattatgg ctaaatcttt cagtctcaag 360 actcagccaa ggtttgtgag gttggcattg attctggcat ttgaaacaag ttcataggtg 420 attgctcggg gacatttcgg ttagaaggaa tcggtttccc gacttttgcc tta 473 <210> 18 <211> 344 <212> DNA <213> HUMAN <400> 18 tcatcaactg gccctggagt gatttcttcc gaaccctcat agcggcaatc ctctacctga 60 tcacctccat tgttgtcctt gttgagagag gaaccactcc aaatcgtcgc agggtactgg 120 gctaatcgta gtgccttggt agagctatgt acttccgtcg gagcagaata gagccatgcc 180 gagatggccg tgtaggactt cctcatctcc tgaactgaat actctcatga atatctccac 240 cacaaacatt cagcagcaat ccacctcttt gagtaaagtg cttattggga actttgcttc 300 cagctgcaat caccctcctg gtgtggcaca tatgtgtgtg ctag 344 <210> 19 <211> 295 <212> DNA <213> HUMAN <400> 19 ggtaatgaaa ccgtgaactt tattgagaac tttcaagcat cataacttga agaagtattt 60 ctcaattcag tttatcgaaa tacttcagct ttccagctgg atctgggatt attgtttcac 120 taccaggttt ccagccagca gggcagactt ctccgtgttt gtcagtgtac tggaatgctt 180 gaaccaaacg tagtgtctca tccactgatc tacccacagg aagatcattc agagtaattt 240 gtcttaggat tcctttgtca tcaataatga agagacctct aagagtgtgg cctga 295 <210> 20 <211> 387 <212> DNA <213> HUMAN <400> 20 tggtgctcat cttcgctcgt ttaatttcag tcagatatta aacatttaca atttttttat 60 ataacaaaac aagaacatgc aaagttacaa atatagaaaa tataaagtac atgcatattt 120 caaagacctg ttaatggtgt ccactttgga ttcttacatg aaacgattca gtgcacattg 180 taagcctaag gaccacgcaa aagggtttcc acatattaag tattcagtac cttacaaaag 240 ttaatgcatt agacacttca gatgttaact gctctaaaca aaactcctaa gtctgtccta 300 tgcaatatat attttatata catatatatt tttacataga atactcacaa agtgcaagcc 360 aataataaca ttgcagaaaa aaaaaaa 387 <210> 21 <211> 343 <212> DNA <213> HUMAN <220> <221> Unsure <222> (253)..(253) <223> Any base may occupy this position. <220> <221> misc_feature <222> (253)..(253) <223> Any base can occupy this position. <400> 21 ttcccagcca tgctttgcaa gatgggcttt gcggtacata ctagtgaact atcgtgaatc 60 cacgggcttt ggccaggaca gcatcctcac cctcccaggc aatgtgggac accaggatga 120 gaaggatgtc cagtttgcag tggaacaagg agcaccagga ggaacacatt gatgcaagcc 180 atgtggacct tatgggtgga tcccatggtg gcatcaatac cagccacatg attggtcagt 240 aaccagagac ctncagggcc tgagtggcac gagaacccgt gataaacata gccaccatgt 300 agggcaccac tgacatccct gactggtaag aggtggaggc tgg 343 <210> 22 <211> 502 <212> DNA <213> HUMAN <400> 22 tttttttttt ttttggctgg gactgcccca aaggcagacg aggtttattg ggcagcagct 60 gggaaaatca gcggttggac ttggccacac gctccagctc gtccttcttc ttaatggcat 120 aggagttcga ggagcccttg gcagcattga tgagctcatc tgccaggcac tcagcaatgg 180 tcttaatgtt ccggaaggca gcctcacgag cgcctgtgca cagcagccag atggcctggt 240 tcacacggcg caggggggac acatccacag cctgtcgtct cacagtcccg gcgcgcccaa 300 tgcgtgtgga gtcctcccgg ggaccactgt tgatgatggc gttcaccagg acctgcagag 360 ggttctcgcc tgtgagcagg tgtatgatct cgaaggcatg cttgacgatg cgcacagtca 420 tgagcttctt gccgttgttg cggccgtgca tcatcatgga gttagtgagg cgctccacaa 480 tgggacactg aactttggga aa 502 <210> 23 <211> 461 <212> DNA <213> HUMAN <400> 23 gcaatgagat aacgttttat tttaattctc accatttata tacaaacaca agtgaataaa 60 acacatcgca aaatggtaaa atttcatatt tagtatttat aggtgcatag tttcatgctc 120 acatattttt gagtattata tatattaaca aatttcacaa tacgtcatta ttcttagaca 180 gtatcattaa aagacaccta aaaatcttat aatatatgat agcaaatcac taacaacttc 240 tgaacaacag caacaaaaaa atagtgagga tttagaaata agtggtagtc acttaggtgt 300 ttttaatttg ttttaacatc gtagattgaa gccacaaaat ccacagcaca caaagaccct 360 gctaccatgt attcacttca gtgaaaggga agcaccgaaa tgctgagtgg gggcaggtac 420 agatacatca atcactgctg atggaagact tcgagataca c 461 <210> 24 <211> 539 <212> DNA <213> HUMAN <400> 24 aattcggaag aggaaggtga agaagggcgt ccaaaggatg accgccacct ccgtggctgt 60 ggctaccttc ccggctgccc gggctccaat ggtttccaca acaacgacac cttccacttc 120 ctgaaatgct gcaacaccac caaatgcaac gagggcccaa tcctggagct tgaaaatctg 180 ccgcagaatg gccgccagtg ttacagctgc aaggggaaca gcacccatgg atgctcctct 240 gaagagactt tcctcattga ctgccgaggc cccatgaatc aatgtctggt agccaccgga 300 ctcacgaacc gaaaaaccaa agctatatgg taagaggctg tgcaaccgcc tcaatgtgcc 360 aacatgccca cctgggtgac gccttcagca tgaaccacat tgatgtctcc tgctgtacta 420 aaagtggctg taaccaccca gacctggatg tccagtaccg cagtggggct gctcctcagc 480 ctggccctgc catctcagcc tcaccatcac cctgctaatg actgccagac tgtggggag 539 <210> 25 <211> 493 <212> DNA <213> HUMAN <400> 25 aatattttat aacttgtcca tacagagttt tgatgatgga gactattttc ctgtgtgggg 60 cacatgcctt ggatttgaag agctttcact gctgattagt ggagagtgct tattaactgc 120 cacagatact gttgacgtgg caatgccgct gaacttcact ggaggtcaat tgcacagcag 180 aatgttccag aattttccta ctgagttgtt gctgtcatta gcagtagaac ctctgactgc 240 caatttccat aagtggagcc tctccgtgaa gaattttaca atgaatgaaa agttaaagaa 300 gtttttcaat gtcttaacta caaatacaga tggcaagatt gagtttattt caacaatgga 360 aggatataag tatccagtat atggtgtcca gtggcatcca gagaaagcac cttatgagtg 420 gaagaatttg gatggcattt cccatgcagc taatgctgtg aaaaccgcat tttatttagc 480 agagtttttg tta 493 <210> 26 <211> 448 <212> DNA <213> HUMAN <400> 26 agtgactcca gaggccttca caaagggcag ctggagtggg gaagtaggac tcaaaggtgc 60 ggcagagagc cccagctggg cacttgttaa ctcctgaggt ccagtcccat cctctgtgcc 120 agttgctctt gcacgtgtgg gaggtgtgac aatcctccca ccagcgctga cagtcctctt 180 tgcataaggg cacatccagg aagcgttctt tgcgccagtc ctgattcacc tgctggatcc 240 agggccccag gttgggtgag cactcataga gacaggtgtc ctggatgaag tggcgcttgc 300 aggcgggctc catcttgccg cagtggtccc agttaaagtt gtacaggcgg gaggtgtcct 360 tgtgcagctc ctggctggtg ctggctgtgc agcaggcatt cttcttccag ggactgcatt 420 ggtcatgcag cttgtcctca ggacctgg 448 <210> 27 <211> 421 <212> DNA <213> HUMAN <400> 27 gtgatctgca tgtggcaggg ctgcgcagtg gagcggccag tgggcaggat gacgagccag 60 acccctctgc cccagtcccc ccggcccagg cggccaacga tgtctactgt tgtggagctg 120 aacgtcgggg gtgagttcca caccaccacc ctgggtaccc tgaggaagtt tccgggctca 180 aagctggcag agatgttctc tagcttagcc aaggcctcca cggacgcgga gggccgcttc 240 ttcatcgacc gccccagcac ctatttcaga cccatcctgg actacctgcg cactgggcaa 300 gtgccacaca gcacatccct gaagtgtacc gtgaggctca gttctacgaa atcaagcctt 360 tggtcaagct gctggaggac atgccacaga tctttggtga gcaggtgtct cggaagcagt 420 t 421 <210> 28 <211> 532 <212> DNA <213> HUMAN <400> 28 cactcccgac ggatctttgc ttctcacgcc agctggatgt gtggaatctg gtgaaaatgt 60 aatgaatacc acttatgttt tctccaggaa gaatcttaaa aggcccatcg ctcatcttcc 120 atgtcctgga aaagccactc ttgctgttcg ctgctgtccg gtctactttg aactgaggcc 180 aatggtggaa acaggtgtgg agctgatgag tctgccctac cgcctggtgt ttgctgtggc 240 ctcggaggat tccgtgcttc tgtatgacac ccagcagtcc ttcccttttg gttacgtgtc 300 taatatacat taccaaaccc tcagtgaaat ttcatggtcc agcgatggtg ccttcctggc 360 catttcttcc acggacggtt actgcccatt tgtgacattt gggaaaaatg aacttggaat 420 tcctttgaaa aagaagccac ttttgaaaat gggaactcct gttaaagcaa ggaaaaccac 480 gggtctgaga catcggggtg tttttccagg accccaaccg ctaaagggga cc 532 <210> 29 <211> 262 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (126)..() <223> Any base. <220> <221> misc_feature <222> (126)..(243) <223> N=any base <400> 29 ggcggctgcc aggatcccgg gcccggatcg cacgaagccc gcgcggccgt ctcctccgcg 60 gccacccctg cgcctcccgc gagctccact tcccatctgc gctaggccac cccagctggg 120 gaagtnntng tggctgtcga gaatgggggt ctgtgggtac ctgttcctgc cctggaagtg 180 cctcgtggtc gtgtctctca ggctgctgtt ccttgtaccc acaggagtgc ccgtgcgcag 240 gangatgcca ccttccccaa ag 262 <210> 30 <211> 449 <212> DNA <213> HUMAN <400> 30 cttttctata aaacttcatt ttgtaatttt tttccaagaa gtagtaaggg ggaaatattg 60 caattatgta aaggtaagga acaatggtgt ataaaaataa tttaagcaca atattaataa 120 caaagcaact ttttttcaag gaaaactagt aggtcatctt gcccaagatt tttccaaagg 180 tattaaatat attttcaata acagtacata caaatacaca tacacaaata taccacacag 240 acacatgtgc acatacatgc acacacacac acacacacac acacacacac acacatatat 300 atatacagct caagtatttt tttggtgtgc attctagcta atccacatag ctaaagtgaa 360 aaaacactga aaagatcaat gcctgagtaa ccttaaattt gaacaaacta tgcattggat 420 gtgaattttt ggaggcatgc taagatttc 449 <210> 31 <211> 483 <212> DNA <213> HUMAN <400> 31 aacagattta atattatatt gcagttttca gcgatgcaga atgagctgca attgtgtttt 60 aaggagaagc caaatgggga tggttgtccc tgcaacatgg tgccactcct gggccatgtg 120 cagcctcagt ggacactctt ccatagcgct gaggccctgc ccgcctccag ttaccctgta 180 ctgcccatgc cttacagtca gtgcgcaggc ttcacctttt catcaccagc ctctctgctc 240 agtgctctgg agttcttgac cttgtccttt atcatgagat ttgctgaaat cactaatgaa 300 aataactccc aaaagcaaca aacaaaaata ttagtttaac tggcactgtg gtatattaaa 360 aggcacaagg gcattgtggc ttaacacttt tgctggatcc caagagacgc acatgatgtt 420 aaaaagagat ctggcagcag tactaatact acatttcagt gtaatcatct tggggtggtt 480 tgg 483 <210> 32 <211> 569 <212> DNA <213> HUMAN <400> 32 tttttttttt tttttttttt tttgcctttg caaagctttt atttcatgtc tgcggcatgg 60 aatccacctg cacatggcat cttagctgtg aaggagaaag cagtgcacga gaaggaatga 120 gtgggcggaa ccaacggcct ccacaagctg ccttccagca gcctgccaag cgcatggcag 180 agagagactg caaacaaaca caagcaaaca gagtctcttc acagctggag tctgaaagct 240 catagtggca tgtgtgaatc tgacaaaatt aaaagtgtgc atagtccatt acatgcataa 300 aacactaata ataatcctgt ttacacgtga ctgcagcagg caggtccagc tccaccactg 360 gcctcctgcc acatcacatc aagtgccatg gtttagaggg tttttcatat gtaattcttt 420 tattctgtaa aaggtaacaa aatatacaga acaaaacttt ccctttttaa aactaatgtt 480 acaaatctgt attatcactt gtatataaat agtatatagc tgatcattaa taaggtgtat 540 aagtacaatg tattctaaaa ctgttaagc 569 <210> 33 <211> 466 <212> DNA <213> HUMAN <400> 33 atccgccaga catttgccaa gttgtagagg tgaccactga gagcgacgag agccggtcag 60 catgagcgag ctctaccctc tgcagatctc ccccgtgtct tcctatgcag aaagcgaaac 120 gactgatagt gtgcccagcg atgaagagag tgccgagggg cggccacact ggcggaagag 180 gaatattgaa ggcaaacagt acctcagcaa catggggact cgaggctcct acctgctgcc 240 cggcatggcg tccttcgtca cttccaacaa accggacctc caggtcacca tcaaagagga 300 gagcaatccg gtgccttaca acagctcctg gccccctttt caagacctcc ccctttcttc 360 ctccatgacc ccagcatcca gcagcagtcg gccagaccgt gagacccggg ccagcgtcat 420 caagaaaaca tcggatatca cccaggcccg cgtcaagagc tgttaa 466 <210> 34 <211> 446 <212> DNA <213> HUMAN <400> 34 tgaacatata aggctagaaa aagaaatttc taagttaaag cagcaaaatg aacagctaat 60 aaaacaaaag aatgaattgt taagcaataa tcagcatctt tccaatgagg tcaaaactct 120 ggaaggaaag aacccttaaa agagaggctc acaaacaagt aacttgtgag aattctccaa 180 agtctcctaa agtgactgga acagcttcta aaaagaaaca aattacaccc gtctcaatgc 240 aaggaacgga atttacaaga tcctgtgcca aaggaatcac caaaagcatt gtttttttga 300 tagccgatca aagtctttac catcactcat ccagttcgct attttgatac atcaagttta 360 ggcctttgtc agaggtgaaa atgcaggaca gagagtgtgg atctcagcca ggtcttggac 420 cgctctcagg aaggatgtgc tgagtg 446 <210> 35 <211> 529 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (392)..(529) <223> N=any base <400> 35 acctctctgt ggtggattta catggccaag ctgtgtgaag aaataggaaa gaagaagtta 60 ccattaacca aggatatgag agaacaagga gttaaaagca atccatgtga ctcaagcctt 120 tcacatactg acagatggta tctgccagtc tcttcaaccc tcttctcact ttttaaaatc 180 ttgttccatg cctccaggtt tatctttgtc ttatctacca gtttattcct gtgaacttca 240 gattgaacca ttcattgcag cagtagcctt aaaaaggctt ttgtttattt ctttggtttg 300 ttaactagtg tcatctattt agagaaacat ttttgttttt aattgctcaa agctgtccgc 360 cgctagtctt atgagccaat ctactaaaac tntggagaaa ctttgtatgt gcacacaaaa 420 gtattcaaga gacagtattg ctaacatctc atcttaatgg cctttggtaa tgagaagttt 480 taggtgcntc caaaccaata taaatgggat aatggtggta atttggggn 529 <210> 36 <211> 423 <212> DNA <213> HUMAN <400> 36 actctgctta cattttataa gtttaaggtc agctgtcaaa aggataacct gtggggttag 60 aacatatcac attgcaacac cctaaattgt ttttaataca ttagcaatct attgggtcaa 120 ctgacatcca ttgtatatac tagtttcttt catgctattt ttattttgtt ttttgcattt 180 ttatcaaatg cagggcccct ttctgatctc accatttcac catgcatctt ggaattcagt 240 aagtgcatat cctaacttgc ccatattcta aatcatctgg ttggttttca gcctagaatt 300 tgatacgctt tttagaaata tgcccagaat agaaaagcta tgttggggca catgtcctgc 360 aaatatggcc ctagaaacaa gtgatatgga atttacttgg tgaataagtt ataaattccc 420 act 423 <210> 37 <211> 403 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (187)..(187) <223> N=any base <400> 37 acagaaacaa gaaggcagct gctgcttcct gctcagcact ggggactatg cctgcgccga 60 tggtagtgtc cggaaagaga cctgccaaga cgccctctcg tccaactatg cccaggctga 120 agtcctcacc ctctcttaaa gcggcaccaa cgtgagagag acaggcagac agacagaaag 180 ccagagntta ggggaaactc tggaacccag acaagaatct tttcgctggg aaagactcag 240 atatccttgt ttgcacagga ctggtggaaa atctcccatg cgaccctcgg ggcccagagc 300 catctgggtc tgatgttctg ttccatttgt acatcgaaga gatatatatg cacatattag 360 tatctatatt cattacatat tatactcttg tgtgtagtgc aaa 403 <210> 38 <211> 363 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (283)..(343) <223> n=any base <400> 38 ttttcaattg tcattgtttt attttttcca aaataacata aaaatacttt ccagttgaat 60 tacataaaaa atttaatcca taaaaccatt atacagtcat gcattggata acaatgggaa 120 tgtgttctga tgaatgcatc cttgggcgat tttgtcactg tgtgaacatc ataagagtgt 180 acttacacaa acctagatgg tatagcctat tgttcctagg ctataagctt gtaaagtgtg 240 ttactgtact gagtactata ggcaactgta acacagtggt acntgtgtat ctaaacaaat 300 ctaaaacatt agaaaaggtn ccaaaaaata tgggtataat ggnttaaaaa aatgggtaca 360 cct 363 <210> 39 <211> 463 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (298)..(463) <223> n=any base <400> 39 tttttttgga aatccaaagg tctcatttat taatggcatt ttatgagtgt catagcattt 60 atttaaacat agagttgtca ttggtaatag aaagttaaac agaaacccaa ctcatgaatc 120 tgaaaatgat ccattaataa tatatagtat tgtccgaagc ctcccagctg ctgggaacat 180 tgggaaggca tgatatttgt cttcaataaa ccattttctt tgtcaggttc accagcttat 240 tttcctttcc cctataaaca tattcccctt gcttttgccc ttgatttaaa taaacatnaa 300 aaagataaca tttagntcca ttcacaagaa actggtaata tgnaaatatt ttgaatggaa 360 acatatctct ttggggagtg gaaatgcggg tngaagtagg acattttagg taaagagtaa 420 agaggtaatn aagggtaatc nctcagggga agtggtaata ntt 463 <210> 40 <211> 322 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(104) <223> n=any base <220> <221> misc_feature <222> (1)..(311) <223> n=any base <400> 40 ntgncaacac gtttaattct gtggccaggc tagcctgtct ccaaggcctg gtggacagca 60 cgtcaccaga ggctgccgna ggagcaggca gggccagccc tganagagga gtgcaggcaa 120 aggcgggggc tctgaagtgg ctgctggagg canagngccc cgggctggga gtgctcagta 180 gccgtcgtta gcccaggtga cctcgtagtc ggggtacttg gctttgattt tctcagttga 240 aatggcgtgc tgggcaagga ccataggcca tggaatagcc gtacacgtga atcttnttgt 300 cntgactctc ngtcgggaga tt 322 <210> 41 <211> 627 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(627) <223> n=any base <400> 41 gtgtttttgg aagtttatta tatgaagatg gtatacaaaa tacattcatc atgactagaa 60 atataggacc aaaccatgtc tgtcttatat ctgtagcata tattcttggt ttgtataaaa 120 gtaactttaa aattccagtt tccttaaata gttatgcaca aaacacacat acacccacac 180 acacacacac acacacacac acacatacag ttacaccact gtcggccaaa gatgcactcc 240 tcctttaatc aatttaaatg aggctagcga gtatctgttt gatgtttgca ttcttgtggg 300 ctaggaaaca aggcacgggt ccctaaaatt aacatctcgg tgtcacttct tggactgaca 360 agacacagac ttgcacatgg tttcagcccc attccaccca gactgttcca cgtacattat 420 ctcagaaact ctgaaaggaa gtgctcgttc tttgttagtg ccaaccattt ttgtcataaa 480 tggcaaatga ttgggatatt atcagttaat tcatgtttca atttcagtgc tattttaatg 540 gacaagcact tgtaactagc ccattattac aagtctccat ttttttccac attaanctcc 600 ngagggacca tctttggccg atggagg 627 <210> 42 <211> 458 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(458) <223> n=any base <400> 42 ttgattatct ggatgcaggt tttattatca ttaggatgac tgtcatcgac aagggatagg 60 ggcttagagg gttatataca aaccacaatt cctaggcgat gtttcaatat tcccacacac 120 atttatccca cagccagaca cagcacaaca ccacaggntt tgcccctaca tatgcttctc 180 caagcagtaa cacagctgtg ggtcagggct ctgcacccac aaagggatgc ccagaaagga 240 gaagatcctg ggtcctgggg gtgaagttta cacatggaga atcctgccag gttggggagg 300 ggatggaagc tggattttnc acacaacgct tcagtcccac cnccaccctt cacttggctt 360 gccctcccca gggggctccc tggtccccac ttggggggag tctttgncaa agacacagaa 420 gggaccatnt ttagccangg ctaanggaag gagcaggc 458 <210> 43 <211> 458 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(458) <223> N=any base <400> 43 tttttntttt tttttttttt tctctgtgac aaactttatt aaattttgca tcagtacagg 60 gcatctctta ttgcatacta gaatcccagg attcaggcgg gtggtaaagt ggcaacgacg 120 aatttgggta tctggtctcc caaaagtact tgccgctcta cccctgactc tgcaatggct 180 gccaggcgga tcactcctcc actggagcca tcccgctcca tggccaaagc gaganatntg 240 gcacgtgaat tgcagacact cttccttggt catgccttcc cggtaggtag catcaacata 300 gccatagatg taggagctcc cggagcctcc aatggcaaag gactgcctta ccatcatacc 360 ccccataggc actggagtac acctngccct ccttncttgg agggtcccag cctgcgaatg 420 atgattccng ccatcaggtc ttcccggtat cggtaaca 458 <210> 44 <211> 152 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(152) <223> N=any base <400> 44 attcggcacg atgggaagat ggcggaggtg ggggagataa tcgagngctg ccgctacccg 60 tgctgcggcg gaaccaggac aacgaagatg agtggcccct gncgaggatc ctgagcgtga 120 aggacatcag tggccggaag cttttctacg tc 152 <210> 45 <211> 305 <212> DNA <213> HUMAN <400> 45 ccagagccag aaatggaaag tacagacttc tgaaaatatc tattggaaaa tgagcaactt 60 gtgattggat catatagtca gccttcagat tcctgggata aggattatga ttcctttgtt 120 ttacccctgt tggaggacaa acaaccatgc tatatattat tcaggttaga ttctcagaat 180 gcccagggat atgaatggat attcattgca tggtctccag atcattctca tgttccgtca 240 aaaaatgttg tatgcagcaa caagagcaac tctgaagaag gaatttggag gtggccacat 300 taaag 305 <210> 46 <211> 240 <212> DNA <213> HUMAN <400> 46 caatcagtaa atatttatta ttttctgtaa ctaaagtact gggctgtggt aggggagaca 60 acaatcaaag acatagcctt gtcttccaga agctcacaat ctagttggga attcaagaat 120 accccttaga aaagttcatt gacaatttac gaggtgctat tagacagtag gagagaaagg 180 catacatacc agggcccagg gaagaagagc tttgtgaatg aagaaggaaa aagtgtaagt 240 <210> 47 <211> 1184 <212> DNA <213> HUMAN <400> 47 atctgccacg atgttgctgc tcagcctgac cctaagcctg gttctcctcg gctcctcctg 60 gggctgcggc attcctgcca tcaaaccggc actgagcttc agccagagga ttgtcaacgg 120 ggagaatgca gtgttgggct cctggccctg gcaggtgtcc ctgcaggaca gcagcggctt 180 ccacttctgc ggtggttctc tcatcagcca gtcctgggtg gtcactgctg cccactgcaa 240 tgtcagccct ggccgccatt ttgttgtcct gggcgagtat gaccgatcat caaacgcaga 300 gcccttgcag gttctgtccg tctctcgggc cattacacac cctagctgga actctaccac 360 catgaacaat gacgtgacgc tgctgaagct cgcctcgcca gcccagtaca caacacgcat 420 ctcgccagtt tgcctggcat cctcaaacga ggctctgact gaaggcctca cgtgtgtcac 480 caccggctgg ggtcgcctca gtggcgtggg caatgtgaca ccagcacatc tgcagcaggt 540 ggctttgccc ctggtcactg tgaatcagtg ccggcagtac tggggctcaa gtatcactga 600 ctccatgatc tgtgcaggtg gcgcaggtgc ctcctcgtgc cagggtgact ccggaggccc 660 tcttgtctgc cagaagggaa acacatgggt gcttattggt attgtctcct ggggcaccaa 720 aaactgcaat gtgcgcgcac ctgctgtgta tactcgagtt agcaagttca gcacctggat 780 caaccaggtc atagcctaca actgagctca ccacaggccc tccccagctc aacccattaa 840 agacccaggc cctgtcccat catgcattca tgtctgtctt cctggctcag gagaaagaag 900 aggctgttga gggtccgact ccctacttgg acttctggca cagaaggggc tgagtgactc 960 cttgagtagc agtggctctt cctagagtag ccatgccgag gccggggccc ccacccctcc 1020 tccagggcaa ccccttggtc ctacagcaag aagccagaac tgttggaatg aatggcagcc 1080 ctccctggag aggcagcctg tttactgaat acagaggata cgtttacaaa ctgaatacgc 1140 ataataaata actgcacatt ctccatccaa aaaaaaaaaa aaaa 1184 <210> 48 <211> 2684 <212> DNA <213> HUMAN <400> 48 cagggcagac catgcgcccg ccaagtccgc tgcccgcccg ctggctatgc gtgctggcag 60 gcgccctcgc ctgggccctt gggccggcgg gcggccaggc ggccaggctg caggaggagt 120 gtgactatgt gcagatgatc gaggtgcagc acaagcagtg cctggaggag gcccagctgg 180 agaatgagac aataggctgc agcaagatgt gggacaacct cacctgctgg ccagccaccc 240 ctcggggcca ggtagttgtc ttggcctgtc ccctcatctt caagctcttc tcctccattc 300 aaggccgcaa tgtaagccgc agctgcaccg acgaaggctg gacgcacctg gagcctggcc 360 cgtaccccat tgcctgtggt ttggatgaca aggcagcgag tttggatgag cagcagacca 420 tgttctacgg ttctgtgaag accggctaca ccattggcta cggcctgtcc ctcgccaccc 480 ttctggtcgc cacagctatc ctgagcctgt tcaggaagct ccactgcacg cggaactaca 540 tccacatgca cctcttcata tccttcatcc tgagggctgc cgctgtcttc atcaaagact 600 tggccctctt cgacagcggg gagtcggacc agtgctccga gggctcggtg ggctgtaagg 660 cagccatggt ctttttccaa tattgtgtca tggctaactt cttctggctg ctggtggagg 720 gcctctacct gtacaccctg cttgccgtct ccttcttctc tgagcggaag tacttctggg 780 ggtacatact catcggctgg ggggtaccca gcacattcac catggtgtgg accatcgcca 840 ggatccattt tgaggattat ggtctgctca ggtgctggga caccatcaac tcctcactgt 900 ggtggatcat aaagggcccc atcctcacct ccatcttggt aaacttcatc ctgtttattt 960 gcatcatccg aatcctgctt cagaaactgc ggcccccaga tatcaggaag agtgacagca 1020 gtccatactc aaggctagcc aggtccacac tcctgctgat ccccctgttt ggagtacact 1080 acatcatgtt cgccttcttt ccggacaatt ttaagcctga agtgaagatg gtctttgagc 1140 tcgtcgtggg gtctttccag ggttttgtgg tggctatcct ctactgcttc ctcaatggtg 1200 aggtgcaggc ggagctgagg cggaagtggc ggcgctggca cctgcagggc gtcctgggct 1260 ggaaccccaa ataccggcac ccgtcgggag gcagcaacgg cgccacgtgc agcacgcagg 1320 tttccatgct gacccgcgtc agcccaggtg cccgccgctc ctccagcttc caagccgaag 1380 tctccctggt ctgaccacca ggatcccagc ccaagcggcc cctcccgccc cttcccactc 1440 gcagcagacg ccggggacag aggcctgccc gggcgcgcca gccccggccc tgggctcgga 1500 ggctgccccc ggccccctgg tctctggtcc ggacactcct agagaacgca gccctagagc 1560 ctgcctggag cgtttctagc aagtgagaga gatgggagct cctctcctgg aggatgcagg 1620 tggaactcag tcattagact cctcctccaa aggcccccta cgccaatcaa gggcaaaaag 1680 tctacatact ttcatcctga ctctgccccc tgctggctct tctgcccaat tggaggaaag 1740 caaccggtgg atcctcaaac aacactggtg tgacctgagg gcagaaaggt tctgcccggg 1800 aaggtcacca gcaccaacac cacggtagtg cctgaaattt caccattgct gtcaagttcc 1860 tttgggttaa gcattaccac tcaggcattt gactgaagat gcagctcact accctattct 1920 ctctttacgc ttagttatca gctttttaaa gtgggttatt ctggagtttt tgtttggaga 1980 gcacacctat cttagtggtt ccccaccgaa gtggactggc ccctgggtca gtctggtggg 2040 aggacggtgc aacccaagga ctgagggact ctgaagcctc tgggaaatga gaaggcagcc 2100 accagcgaat gctaggtctc ggactaagcc tacctgctct ccaagtctca gtggcttcat 2160 ctgtcaagtg ggactctgtc acaccagcca ttcttatctc tctgtgctgt ggaagcaaca 2220 ggaatcaaga gactgccctc cttgtccacc cacctatgtg ccaactgttg taactaggct 2280 cagagatgtg cacccatggg ctctgacaga aagcagatcc tcaccctgct acacatacag 2340 gatttgaact cagatctgtc tgataggaat gtgaaagcac ggactcttac tgctaacttt 2400 tgtgtatcgt aaccagccag atcctcttgg ttatttgttt accacttgta ttattaatgc 2460 cattatccct gaattcccct tgccacccca ccctccctgg agtgtggctg aggaggcctc 2520 catctcatgt atcatctgga taggagcctg ctggtcacag cctcctctgt ctgcccttca 2580 ccccagtggc cactcagctt cctacccaca cctctgccag aagatcccct caggactgca 2640 acaggcttgt gcaacaataa atgttggctt ggaaaaaaaa aaaa 2684 <210> 49 <211> 309 <212> DNA <213> HUMAN <400> 49 atggcaggac aagcgtttag aaagtttctt ccactctttg accgagtatt ggttgaaagg 60 agtgctgctg aaactgtaac caaaggaggc attatgcttc cagaaaaatc tcaaggaaaa 120 gtattgcaag caacagtagt cgctgttgga tcgggttcta aaggaaaggg tggagagatt 180 caaccagtta gcgtgaaagt tggagataaa gttcttctcc cagaatatgg aggcaccaaa 240 gtagttctag atgacaagga ttatttccta tttagagatg gtgacattct tggaaagtac 300 gtagactga 309 <210> 50 <211> 1838 <212> DNA <213> HUMAN <400> 50 aattcttcac ctcttttctc agctccctgc agcatgggtg ctgggccctc cttgctgctc 60 gccgccctcc tgctgcttct ctccggcgac ggcgccgtgc gctgcgacac acctgccaac 120 tgcacctatc ttgacctgct gggcacctgg gtcttccagg tgggctccag cggttcccag 180 cgcgatgtca actgctcggt tatgggacca caagaaaaaa aagtagtggt gtaccttcag 240 aagctggata cagcatatga tgaccttggc aattctggcc atttcaccat catttacaac 300 caaggctttg agattgtgtt gaatgactac aagtggtttg ccttttttaa gtataaagaa 360 gagggcagca aggtgaccac ttactgcaac gagacaatga ctgggtgggt gcatgatgtg 420 ttgggccgga actgggcttg tttcaccgga aagaaggtgg gaactgcctc tgagaatgtg 480 tatgtcaaca cagcacacct taagaattct caggaaaagt attctaatag gctctacaag 540 tatgatcaca actttgtgaa agctatcaat gccattcaga agtcttggac tgcaactaca 600 tacatggaat atgagactct taccctggga gatatgatta ggagaagtgg tggccacagt 660 cgaaaaatcc caaggcccaa acctgcacca ctgactgctg aaatacagca aaagattttg 720 catttgccaa catcttggga ctggagaaat gttcatggta tcaattttgt cagtcctgtt 780 cgaaaccaag catcctgtgg cagctgctac tcatttgctt ctatgggtat gctagaagcg 840 agaatccgta tactaaccaa caattctcag accccaatcc taagccctca ggaggttgtg 900 tcttgtagcc agtatgctca aggctgtgaa ggcggcttcc cataccttat tgcaggaaag 960 tacgcccaag attttgggct ggtggaagaa gcttgcttcc cctacacagg cactgattct 1020 ccatgcaaaa tgaaggaaga ctgctttcgt tattactcct ctgagtacca ctatgtagga 1080 ggtttctatg gaggctgcaa tgaagccctg atgaagcttg agttggtcca tcatgggccc 1140 atggcagttg cttttgaagt atatgatgac ttcctccact acaaaaaggg gatctaccac 1200 cacactggtc taagagaccc tttcaacccc tttgagctga ctaatcatgc tgttctgctt 1260 gtgggctatg gcactgactc agcctctggg atggattact ggattgttaa aaacagctgg 1320 ggcaccggct ggggtgagaa tggctacttc cggatccgca gaggaactga tgagtgtgca 1380 attgagagca tagcagtggc agccacacca attcctaaat tgtagggtat gccttccagt 1440 atttcataat gatctgcatc agttgtaaag gggaattggt atattcacag actgtagact 1500 ttcagcagca atctcagaag cttacaaata gatttccatg aagatatttg tcttcagaat 1560 taaaactgcc cttaatttta atataccttt caatcggcca ctggccattt ttttctaagt 1620 attcaattaa gtgggaattt tctggaagat ggtcagctat gaagtaatag agtttgctta 1680 atcatttgta attcaaacat gctatatttt ttaaaatcaa tgtgaaaaca tagacttatt 1740 tttaaattgt accaatcaca agaaaataat ggcaataatt atcaaaactt ttaaaataga 1800 tgctcatatt tttaaaataa agttttaaaa ataactgc 1838 <210> 51 <211> 2306 <212> DNA <213> HUMAN <400> 51 aagagacaag aggtgccttg tgggcagata gggggctggg agggggcctg cccggaagca 60 gtggtggccc gtggcaggct tctcactggg taggaccggg ccctctgttg caccccctca 120 ccctgctctc tgccctcagg agtggctaag caggttcggt tacctgcccc cggctgaccc 180 cacaacaggg cagctgcaga cgcaagagga gctgtctaag gccatcacag ccatgcagca 240 gtttggtggc ctggaggcca ccggcatcct ggacgaggcc accctggccc tgatgaaaac 300 cccacgctgc tccctgccag acctccctgt cctgacccag gctcgcagga gacgccaggc 360 tccagccccc accaagtgga acaagaggaa cctgtcgtgg agggtccgga cgttcccacg 420 ggactcacca ctggggcacg acacggtgcg tgcactcatg tactacgccc tcaaggtctg 480 gagcgacatt gcgcccctga acttccacga ggtggcgggc agcaccgccg acatccagat 540 cgacttctcc aaggccgacc ataacgacgg ctaccccttc gacggccccg gcggcaccgt 600 ggcccacgcc ttcttccccg gccaccacca caccgccggg gacacccact ttgacgatga 660 cgaggcctgg accttccgct cctcggatgc ccacgggatg gacctgtttg cagtggctgt 720 ccacgagttt ggccacgcca ttgggttaag ccatgtggcc gctgcacact ccatcatgcg 780 gccgtactac cagggcccgg tgggtgaccc gctgcgctac gggctcccct acgaggacaa 840 ggtgcgcgtc tggcagctgt acggtgtgcg ggagtctgtg tctcccacgg cgcagcccga 900 ggagcctccc ctgctgccgg agcccccaga caaccggtcc agcgccccgc ccaggaagga 960 cgtgccccac agatgcagca ctcactttga cgcggtggcc cagatccggg gtgaagcttt 1020 cttcttcaaa ggcaagtact tctggcggct gacgcgggac cggcacctgg tgtccctgca 1080 gccggcacag atgcaccgct tctggcgggg cctgccgctg cacctggaca gcgtggacgc 1140 cgtgtacgag cgcaccagcg accacaagat cgtcttcttt aaaggagaca ggtactgggt 1200 gttcaaggac aataacgtag aggaaggata cccgcgcccc gtctccgact tcagcctccc 1260 gcctggcggc atcgacgctg ccttctcctg ggcccacaat gacaggactt atttctttaa 1320 ggaccagctg tactggcgct acgatgacca cacgaggcac atggaccccg gctaccccgc 1380 ccagagcccc ctgtggaggg gtgtccccag cacgctggac gacgccatgc gctggtccga 1440 cggtgcctcc tacttcttcc gtggccagga gtactggaaa gtgctggatg gcgagctgga 1500 ggtggcaccc gggtacccac agtccacggc ccgggactgg ctggtgtgtg gagactcaca 1560 ggccgatgga tctgtggctg cgggcgtgga cgcggcagag gggccccgcg cccctccagg 1620 acaacatgac cagagccgct cggaggacgg ttacgaggtc tgctcatgca cctctggggc 1680 atcctctccc ccgggggccc caggcccact ggtggctgcc accatgctgc tgctgctgcc 1740 gccactgtca ccaggcgccc tgtggacagc ggcccaggcc ctgacgctat gacacacagc 1800 gcgagcccat gagaggacag aggcggtggg acagcctggc cacagagggc aaggactgtg 1860 ccggagtccc tgggggaggt gctggcgcgg gatgaggacg ggccaccctg gcaccggaag 1920 gccagcagag ggcacggccc gccagggctg ggcaggctca ggtggcaagg acggagctgt 1980 cccctagtga gggactgtgt tgactgacga gccgaggggt ggccgctcca gaagggtgcc 2040 cagtcaggcc gcaccgccgc cagcctcctc cggccctgga gggagcatct cgggctgggg 2100 gcccacccct ctctgtgccg gcgccaccaa ccccacccac actgctgcct ggtgctcccg 2160 ccggcccaca gggcctccgt ccccaggtcc ccagtggggc agccctcccc acagacgagc 2220 cccccacatg gtgccgcggc acgtcccccc tgtgacgcgt tccagaccaa catgacctct 2280 ccctgctttg tagcggcccg gaattc 2306 <210> 52 <211> 1932 <212> DNA <213> HUMAN <400> 52 cagcgagccg cagcgcaatc ccggcgctcg cccaaggacc ctggaagcta ccgttacccc 60 gccggcagcg tgggcgccat gagcagctcg ggactgaatt cggagaaggt agctgctctg 120 atacagaaac tgaattccga cccccagttc gtacttgccc agaatgtcgg gaccacccac 180 gacctgctgg acatctgtct gaagcgggcc acggtgcagc gcgcgcagca tgtgttccag 240 cacgccgtgc cccaggaggg caagccaatc accaaccaga agagctcagg gcgatgctgg 300 atcttttctt gtctgaatgt tatgaggctt ccattcatga aaaagttaaa tattgaagaa 360 tttgagttta gccaatctta cctgtttttt tgggacaagg ttgaacgctg ttatttcttc 420 ttgagtgctt ttgtggacac agcccagaga aaggagcctg aggatgggag gctggtgcag 480 tttttgctta tgaaccctgc aaatgatggt ggccaatggg atatgcttgt taatattgtt 540 gaaaaatatg gtgttatccc taagaaatgc ttccctgaat cttatacaac agaggcaacc 600 agaaggatga atgatattct gaatcacaag atgagagaat tctgtatacg actgcggaac 660 ctggtacaca gtggagcaac caaaggagaa atctcggcca cacaggacgt catgatggag 720 gagatattcc gagtggtgtg catctgtttg ggtaatccac cagagacatt cacctgggaa 780 tatcgagaca aagataaaaa ttatcagaaa attggcccca taacaccctt ggagttttac 840 agggaacatg tcaagccact cttcaatatg gaagataaga tttgtttagt gaatgaccct 900 aggccccagc acaagtacaa caaactttac acagtggaat acttaagcaa tatggttggt 960 gggagaaaaa ctctatacaa caaccagccc attgacttcc tgaaaaagat ggttgctgcc 1020 tccatcaaag atggagaggc tgtgtggttt ggctgtgatg ttggaaaaca cttcaatagc 1080 aagctgggcc tcagtgacat gaatctctat gaccatgagt tagtgtttgg tgtctccttg 1140 aagaacatga ataaagcgga gaggctgact tttggtgagt cacttatgac ccacgccatg 1200 accttcactg ctgtctcaga gaaggatgat caggatggtg ctttcacaaa atggagagtg 1260 gagaattcat ggggtgaaga ccatggccac aaaggttacc tgtgcatgac agatgagtgg 1320 ttctctgagt atgtctacga agtggtggtg gacaggaagc atgtccctga agaggtgcta 1380 gctgtgttag agcaggaacc cattatcctg ccagcatggg accccatggg agctttggct 1440 gagtgatact gccctccagc tctttcctcc ttccatggaa cctgacgtag ctgcaaagga 1500 cagatccagg gactgaagcc aaagttatgc aagggactgt gtgttgccac aggacacagt 1560 cagatttcca gtctccacca ggaacctctt cagaaagtgt gctttatgct gaaacagaat 1620 actgttaaag gaaaaaaaag aggggggaag atcaggtcat actatctact ctcctcatct 1680 ctaacagctc aggatctctt agcattttaa ttagatgtaa ttgtttgtct ttaactgtca 1740 aaaagtttgg ttctgtgtct gtgttttaat aagacgagag gacgagcgat tgaggtgtat 1800 ggagagaaaa cagacctaat gctccttgtt cctagagtag agtggaggga gggtggccta 1860 agagttgagc tctcggaact gcatgctgct ggacagtatc actgtctttc ctagatggca 1920 gtcactgaat tc 1932 <210> 53 <211> 774 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(774) <223> N=any base <400> 53 cggcacgagg gtgctgcttg tgtgctcgtt tggtgcggac ctggtacctc ttyttgtgaa 60 gcggcagctg aggagactcc ggcgctcgcc atggccgacg aaaagcccaa ggaaggagtc 120 aagactgaga acaacgatca tattaatttg aaggtggcgg ggcaggatgg ttctgtggtg 180 cagtttaaga ttaagaggca tacaccactt agtaaactaa tgaaagccta ttgtgaacga 240 cagggattgt caatgaggca gatcagattc cgatttgacg ggcaaccaat caatgaaaca 300 gacacacctg cacagttgga aatggaggat gaagatacaa ttgatgtgtt ccaacagcag 360 acgggaggtg tctactgaaa agggaacctg cttctttact ccagaactct gttctttaaa 420 gaccaagatt acattctcaa ttagaaaact gcaatttggt tccaccacat cctgactact 480 accgtatagt tttctctatt ctttcatttc ccccttcccc attcctttat tgtacataaa 540 gtaactggta tatgtgcaca agcatattgc attttttttt tttttaacta aacagccaat 600 ggtatgtttt gattgacatc caagtggaga cggggatggg gaaaaatact gattctgtgg 660 aaaatacccc cctttctccc attagtggnc atgctccatt cagcccttaa acctttataa 720 tcccaggtaa ggtaatttng cccncaccgg ttttacccaa aaaaaaaaaa actt 774 <210> 54 <211> 723 <212> DNA <213> HUMAN <400> 54 gtgtactatt agccatggtc aaccccaccg tgttcttcga cattgccgtc gacggcgagc 60 ccttgggccg cgtctccttt gagctgtttg cagacaaggt cccaaagaca gcagaaaatt 120 ttcgtgctct gagcactgga gagaaaggat ttggttataa gggttcctgc tttcacagaa 180 ttattccagg gtttatgtgt cagggtggtg acttcacacg ccataatggc actggtggca 240 agtccatcta tggggagaaa tttgaagatg agaacttcat cctaaagcat acgggtcctg 300 gcatcttgtc catggcaaat gctggaccca acacaaatgg ttcccagttt ttcatctgca 360 ctgccaagac tgagtggttg gatggcaagc atgtggtgtt tggcaaagtg aaagaaggca 420 tgaatattgt ggaggccatg gagcgctttg ggtccaggaa tggcaagacc agcaagaaga 480 tcaccattgc tgactgtgga caactcgaat aagtttgact tgtgttttat cttaaccacc 540 agatcattcc ttctgtagct caggagagca cccctccacc ccatttgctc gcagtatcct 600 agaatctttg tgctctcgct gcagttccct ttgggttcca tgttttcctt gttccctccc 660 atgcctagct ggattgcaga gttaagttta tgattatgaa ataaaaacta aataacaatt 720 gtc 723 <210> 55 <211> 1291 <212> DNA <213> HUMAN <400> 55 gctctttcca acgctgtaaa aaaggacaga ggctgttccc tatggcagaa ggcaaccaca 60 gaaaaaagcc acttaaggtg ttggaatccc tgggcaaaga tttcctcact ggtgttttgg 120 ataacttggt ggaacaaaat gtactgaact ggaaggaaga ggaaaaaaag aaatattacg 180 atgctaaaac tgaagacaaa gttcgggtca tggcagactc tatgcaagag aagcaacgta 240 tggcaggaca aatgcttctt caaacctttt ttaacataga ccaaatatcc cccaataaaa 300 aagctcatcc gaatatggag gctggaccac ctgagtcagg agaatctaca gatgccctca 360 agctttgtcc tcatgaagaa ttcctgagac tatgtaaaga aagagctgaa gagatctatc 420 caataaagga gagaaacaac cgcacacgcc tggctctcat catatgcaat acagagtttg 480 accatctgcc tccgaggaat ggagctgact ttgacatcac agggatgaag gagctacttg 540 agggtctgga ctatagtgta gatgtagaag agaatctgac agccagggat atggagtcag 600 cgctgagggc atttgctacc agaccagagc acaagtcctc tgacagcaca ttcttggtac 660 tcatgtctca tggcatcctg gagggaatct gcggaactgt gcatgatgag aaaaaaccag 720 atgtgctgct ttatgacacc atcttccaga tattcaacaa ccgcaactgc ctcagtctga 780 aggacaaacc caaggtcatc attgtccagg cctgcagagg tgcaaaccgt ggggaactgt 840 gggtcagaga ctctccagca tccttggaag tggcctcttc acagtcatct gagaacctgg 900 aggaagatgc tgtttacaag acccacgtgg agaaggactt cattgctttc tgctcttcaa 960 cgccacacaa cgtgtcctgg agagacagca caatgggctc tatcttcatc acacaactca 1020 tcacatgctt ccagaaatat tcttggtgct gccacctaga ggaagtattt cggaaggtac 1080 agcaatcatt tgaaactcca agggccaaag ctcaaatgcc caccatagaa cgactgtcca 1140 tgacaagata tttctacctc tttcctggca attgaaaatg gaagccacaa gcagcccagc 1200 cctccttaat caacttcaag gagcaccttc attagtacag cttgcatatt taacattttg 1260 tatttcaata aaagtgaaga caaaaaaaaa a 1291 <210> 56 <211> 1552 <212> DNA <213> HUMAN <400> 56 ccgccgccgc gcatgggctg cctcggaacg agtaagaccg aggaccagcg caacgaggag 60 aaggcgcagc gtgaggccaa caaaaagatc gagaagcagc tgcagaagga caagcaggtc 120 taccgggcca cgcaccgcct gctgctgctg ggtgctggag aatctggtaa aagcaccatt 180 gtgaagcaga tgaggatcct gcatgttaat gggtttaatg gagagggcgg cgaagaggac 240 ccgcaggctg caaggagcaa cagcgatggt gagaaggcaa ccaaagtgca ggacatcaaa 300 aacaacctga aagaggcgat tgaaaccatt gtggccgcca tgagcaacct ggtgcccccc 360 gtggagctgg ccaaccccga gaaccagttc agagtggact acatcctgag tgtgatgaac 420 gtgcctgact ttgacttccc tcccgaattc tatgagcatg ccaaggctct gtgggaggat 480 gaaggagtgc gtgcctgcta cgaacgctcc aacgagtacc agctgattga ctgtgcccag 540 tacttcctgg acaagatcga cgtgatcaag caggctgact atgtgccgag cgatcaggac 600 ctgcttcgct gccgtgtcct gacttctgga atctttgaga ccaagttcca ggtggacaaa 660 gtcaacttcc acatgtttga cgtgggtggc cagcgcgatg aacgccgcaa gtggatccag 720 tgcttcaacg atgtgactgc catcatcttc gtggtggcca gcagcagcta caacatggtc 780 atccgggagg acaaccagac caaccgcctg caggaggctc tgaacctctt caagagcatc 840 tggaacaaca gatggctgcg caccatctct gtgatcctgt tcctcaacaa gcaagatctg 900 ctcgctgaga aagtccttgc tgggaaatcg aagattgagg actactttcc agaatttgct 960 cgctacacta ctcctgagga tgctactccc gagcccggag aggacccacg cgtgacccgg 1020 gccaagtact tcattcgaga tgagtttctg aggatcagca ctgccagtgg agatgggcgt 1080 cactactgct accctcattt cacctgcgct gtggacactg agaacatccg ccgtgtgttc 1140 aacgactgcc gtgacatcat tcagcgcatg caccttcgtc agtacgagct gctctaagaa 1200 ggaaccccca aatttaatta aagccttaag cacaattaat taaaagtgaa acgtaattgt 1260 acaagcagtt aatcacccac catagggcat gattaacaaa gcaacctttc ccttcccccg 1320 agtgattttg cgaaaccccc ttttcccttc agcttgctta gatgttccaa atttagaagc 1380 ttaaggcggc ctacagaaaa aggaaaaaag gccacaaaag ttccctctca ctttcagtaa 1440 aaataaataa aacagcagca gcaaacaaat aaaatgaaat aaaagaaaca aatgaaataa 1500 atattgtgtt gtgcagcatt aaaaaaaatc aaaataaaaa ttaaatgtga gc 1552 <210> 57 <211> 1106 <212> DNA <213> HUMAN <400> 57 ttgctgaaat aaaacacaag tatctctggt cagagcctca gaattgctca gccaccaaaa 60 gtaactacct tcgaggtact ggtccctacc caccttccgt ggactggcgg aaaaaaggaa 120 attttgtctc acctgtgaaa aatcagggtg cctgcggcag ttgctggact ttctccacca 180 ctggggccct ggagtctgca atcgccatcg caaccggaaa gatgctgtcc ttggcggaac 240 agcagctggt ggactgcgcc caggacttca ataattacgg ctgccaaggg ggtctcccca 300 gccaggcttt cgagtatatc ctgtacaaca aggggatcat gggtgaagac acctacccct 360 accagggcaa ggatggttat tgcaagttcc aacctggaaa ggccatcggc tttgtcaagg 420 atgtagccaa catcacaatc tatgacgagg aagcgatggt ggaggctgtg gccctctaca 480 accctgtgag ctttgccttt gaggtgactc aggacttcat gatgtataga acgggcatct 540 actccagtac ttcctgccat aaaactccag ataaagtaaa ccatgcagta ctggctgttg 600 ggtatggaga aaaaaatggg atcccttact ggatcgtgaa aaactcttgg ggtccccagt 660 ggggaatgaa cgggtacttc ctcatcgagc gcggaaagaa catgtgtggc ctggctgcct 720 gcgcctccta ccccatccct ctggtgtgag ccgtggcagc cgcagcgcag actggcggag 780 aaggagagga acgggcagcc tgggcctggg tggaaatcct gccctggagg aagttgtggg 840 gagatccact gggaccccca acattctgcc ctcacctctg tgcccagcct ggaaacctac 900 agacaaggag gagttccacc atgagctcac ccgtgtctat gacgcaaaga tcaccagcca 960 tgtgccttag tgtccttctt aacagactca aaccacatgg accacgaata ttctttctgt 1020 ccagaagggc tactttccac atatagagct ccagggactg tcttttctgt attcgctgtt 1080 caataaacat tgagtgagca cctcca 1106 <210> 58 <211> 725 <212> DNA <213> HUMAN <400> 58 ctaacccaga aacatccaat tctcaaactg aagctcgcac tctcgcctcc agcatgaaag 60 tctctgccgc ccttctgtgc ctgctgctca tagcagccac cttcattccc caagggctcg 120 ctcagccaga tgcaatcaat gccccagtca cctgctgtta taacttcacc aataggaaga 180 tctcagtgca gaggctcgcg agctatagaa gaatcaccag cagcaagtgt cccaaagaag 240 ctgtgatctt caagaccatt gtggccaagg agatctgtgc tgaccccaag cagaagtggg 300 ttcaggattc catggaccac ctggacaagc aaacccaaac tccgaagact tgaacactca 360 ctccacaacc caagaatctg cagctaactt attttcccct agctttcccc agacaccctg 420 ttttatttta ttataatgaa ttttgtttgt tgatgtgaaa cattatgcct taagtaatgt 480 taattcttat ttaagttatt gatgttttaa gtttatcttt catggtacta gtgtttttta 540 gatacagaga cttggggaaa ttgcttttcc tcttgaacca cagttctacc cctgggatgt 600 tttgagggtc tttgcaagaa tcattaatac aaagaatttt ttttaacatt ccaatgcatt 660 gctaaaatat tattgtggaa atgaatattt tgtaactatt acaccaaata aatatatttt 720 tgtac 725 <210> 59 <211> 2019 <212> DNA <213> HUMAN <400> 59 acgtgtatcg ctgccgtcaa gatggagggg cctttgtccg tgttcggtga ccgcagcact 60 ggggaaacga tccgctccca aaacgttatg gctgcagctt cgattgccaa tattgtaaaa 120 agttctcttg gtccagttgg cttggataaa atgttggtgg atgatattgg tgatgtaacc 180 attactaacg atggtgcaac catcctgaag ttactggagg tagaacatcc tgcagctaaa 240 gttctttgtg agctggctga tctgcaagac aaagaagttg gagatggaac tacttcagtg 300 gttattattg cagcagaact cctaaaaaat gcagatgaat tagtcaaaca gaaaattcat 360 cccacatcag ttattagtgg ctatcgactt gcttgcaagg aagcagtgcg ttatatcaat 420 gaaaacctaa ttgttaacac agatgaactg ggaagagatt gcctgattaa tgctgctaag 480 acatccatgt cttccaaaat cattgggata aatggtgatt tctttgctaa catggtagta 540 gatgctgtac ttgctattaa atacacagac ataagaggcc agccacgcta tccagtcaac 600 tctgttaata ttttgaaagc ccatgggaga agtcaaatgg agagtatgct catcagtggc 660 tatgcactca actgtgtggt gggatcccag ggcatgccca agagaatcgt aaatgcaaaa 720 attgcttgcc ttgacttcag cctgcaaaaa acaaaaatga agcttggtgt acaggtggtc 780 attacagacc ctgaaaaact ggaccaaatt agacagagag aatcagatat caccaaggag 840 agaattcaga agatcctggc aactggtgcc aatgttattc taaccactgg tggaattgat 900 gatatgtgtc tgaagtattt tgtggaggct ggtgctatgg cagttagaag agttttaaaa 960 agggacctta aacgcattgc caaagcttct ggagcaacta ttctgtcaac cctggccaat 1020 ttggaaggtg aagaaacttt tgaagctgca atgttgggac aggcagaaga agtggtacag 1080 gagagaattt gtgatgatga gctgatctta atcaaaaata ctaaggctcg tacgtctgca 1140 tcgattatct tacgtggggc aaatgatttc atgtgtgatg agatggagcg ctctttacat 1200 gatgcacttt gtgtagtgaa gagagttttg gagtcaaaat ctgtggttcc cggtgggggt 1260 gctgtagaag cagccctttc catatacctt gaaaactatg caaccagcat ggggtctcgg 1320 gaacagcttg cgattgcaga gtttgcaaga tcacttcttg ttattcccaa tacactagca 1380 gttaatgctg cccaggactc cacagatctg gttgcaaaat taagagcttt tcataatgag 1440 gcccaggtta acccagaacg taaaaatcta aaatggattg gtcttgattt gagcaatggt 1500 aaacctcgag acaacaaaca agcaggggtg tttgaaccaa ccatagttaa agttaagagt 1560 ttgaaatttg caacagaagc tgcaatcacc attcttcgaa ttgatgatct tattaaatta 1620 catccagaaa tccttcggat taaacatgga agttatgaag atgctgttca ctctggagcc 1680 cttaatgatt gatctgatgt tccttttatt tataacaatg ttaaatgcaa tgtcttgtac 1740 cttgagttga gtattacaca ttaaagtaaa gtacaagctg taaacttggg tttttgtgat 1800 gtaggaaatg gtttccatct gtactttggt cctctgattt cagatattgc aacctagtac 1860 tttattagtt taaaaagaaa ttgaggttgt tcaaagttta agcaattcat tctctctgaa 1920 cacacattgc tattcccatc ccacccccaa tgcacagggc tgcaacacca cgacttctgc 1980 ccattctctc cagtgtgtgt aacagggtca caagaattc 2019 <210> 60 <211> 3016 <212> DNA <213> HUMAN <400> 60 gaattcgggt gagccagctc cgggagaaca gcatgtacac cagcctcagt gttacagagt 60 gtgggtacat caaggtgaat ggtgagcaga aactataacc tgttagtcct tctacacctc 120 atctgctaca agttctggct tagacatgga tattctttgt gaagaaaata cttctttgag 180 ctcaactacg aactccctaa tgcaattaaa tgatgacacc aggctctaca gtaatgactt 240 taactctgga gaagctaaca cttctgatgc atttaactgg acagtcgact ctgaaaatcg 300 aaccaacctt tcctgtgaag ggtgcctctc accgtcgtgt ctctccttac ttcatctcca 360 ggaaaaaaac tggtctgctt tactgacagc cgtagtgatt attctaacta ttgctggaaa 420 catactcgtc atcatggcag tgtccctaga gaaaaagctg cagaatgcca ccaactattt 480 cctgatgtca cttgccatag ctgatatgct gctgggtttc cttgtcatgc ccgtgtccat 540 gttaaccatc ctgtatgggt accggtggcc tctgccgagc aagctttgtg cagtctggat 600 ttacctggac gtgctcttct ccacggcctc catcatgcac ctctgcgcca tctcgctgga 660 ccgctacgtc gccatccaga atcccatcca ccacagccgc ttcaactcca gaactaaggc 720 atttctgaaa atcattgctg tttggaccat atcagtaggt atatccatgc caataccagt 780 ctttgggcta caggacgatt cgaaggtctt taaggagggg agttgcttac tcgccgatga 840 taactttgtc ctgatcggct cttttgtgtc atttttcatt cccttaacca tcatggtgat 900 cacctacttt ctaactatca agtcactcca gaaagaagct actttgtgtg taagtgatct 960 tggcacacgg gccaaattag cttctttcag cttcctccct cagagttctt tgtcttcaga 1020 aaagctcttc cagcggtcga tccataggga gccagggtcc tacacaggca ggaggactat 1080 gcagtccatc agcaatgagc aaaaggcatg caaggtgctg ggcatcgtct tcttcctgtt 1140 tgtggtgatg tggtgccctt tcttcatcac aaacatcatg gccgtcatct gcaaagagtc 1200 ctgcaatgag gatgtcattg gggccctgct caatgtgttt gtttggatcg gttatctctc 1260 ttcagcagtc aacccactag tctacacact gttcaacaag acctataggt cagccttttc 1320 acggtatatt cagtgtcagt acaaggaaaa caaaaaacca ttgcagttaa ttttagtgaa 1380 cacaataccg gctttggcct acaagtctag ccaacttcaa atgggacaaa aaaagaattc 1440 aaagcaagat gccaagacaa cagataatga ctgctcaatg gttgctctag gaaagcagca 1500 ttctgaagag gcttctaaag acaatagcga cggagtgaat gaaaaggtga gctgtgtgtg 1560 ataggctagt tgccgtggca actgtggaag gcacactgag caagttttca cctatctgga 1620 aaaaaaaaat atgagattgg aaaaaattag acaagtctag tggaaccaac gatcatatct 1680 gtatgcctca ttttattctg tcaatgaaaa gcggggttca atgctacaaa atgtgtgctt 1740 ggaaaatgtt ctgacagcat ttcagctgtg agctttctga tacttattta taacattgta 1800 aatgatatgt ctttaaaatg attcactttt attgtataat tatgaagccc taagtaaatc 1860 taaattaact tctattttca agtggaaacc ttgctgctat gctgttcatt gatgacatgg 1920 gattgagttg gttacctatt gccgtaaata aaaatagcta taaatagtga aaattttatt 1980 gaatataatg gcctcttaaa aattatcttt aaaacttact atggtatata ttttgaaagg 2040 agaaaaaaaa aaagccacta aggtcagtgt tataaaatct gtattgctaa gataattaaa 2100 tgaaatactt gacaacattt ttcatagata ccattttgaa atattcacaa ggttgctggc 2160 atttgctgca tttcaagtta attctcagaa gtgaaaaaga cttcaaatgt tattcaataa 2220 ctattgctgc tttctcttct acttcttgtg ctttactctg aatttccagt gtggtcttgt 2280 ttaatatttg ttcctctagg taaactagca aaaggatgat ttaacattac caaatgcctt 2340 tctagcaatt gcttctctaa aacagcacta tcgaggtatt tggtaacttg ctgtgaaatg 2400 actgcatcat gcatgcactc ttttgagcag taaatgtata ttgatgtaac tgtgtcagga 2460 ttgaggatga actcaggttt ccggctactg acagtggtag agtcctagga catctctgta 2520 aaaagcaggt gactttccta tgacactcat caggtaaact gatgctttca gatccatcgg 2580 tttatactat ttattaaaac cattctgctt ggttccacaa tcatctattg agtgtacatt 2640 tatgtgtgaa gcaaatttct agatatgaga aatataaaaa taattaaaac aaaatccttg 2700 ccttcaaacg aaatggctcg gccaggcacg gaggctcgtg catgtaatcc tagcactttg 2760 ggaggctgag atgggaggat cacttgaggc caagagtttg agaccaacct gggtaacaaa 2820 gtgagacctc cctgtctcta caaaaaaaat caaaaaatta tctgatcctt gtggcacaca 2880 actgtggtcc cagctacagg ggaggctgag acgcaaggat cacttgagcc cagaagctca 2940 aggctgcagt gagccaagtt cacaccactg ccatttcctc ctgggcaaca gagtgagacc 3000 ctatcacccc gaattc 3016 <210> 61 <211> 4131 <212> DNA <213> HUMAN <400> 61 tcaagctcgc cccgcgcagc ccgagccggg ctgggcgctg tcctcggggg cctggggaac 60 cgcgcggttt ggagatcgga ggcacctgga acccgtggca agcgccgagc cgggagacag 120 cccgaggaac cacgggttct ggagctagga gccggaagct gggagtccgg aggagagcgg 180 agcccggagc ccggagcccg gggcggcgcg tctgggtctg gcgcttcccg actggacggc 240 gcgcccgctg gtcttcgcca cgcgccctcc cctgggctcg cgttcatcgg tccccgcctg 300 agacgcgccc actcctgccc ggacttccag ccccggaggc gccggacaga gccgcggact 360 ccagcgccca ccatgcgcct caacagctcc gcgccgggaa ccccgggcac gccggccgcc 420 gaccccttcc agcgggcgca ggccggactg gaggaggcgc tgctggcccc gggcttcggc 480 aacgcttcgg gcaacgcgtc ggagcgcgtc ctggcggcac ccagcagcga gctggacgtg 540 aacaccgaca tctactccaa agtgctggtg accgccgtgt acctggcgct cttcgtggtg 600 ggcacggtgg gcaacacggt gacggcgttc acgctggcgc ggaagaagtc gctgcagagc 660 ctgcagagca cggtgcatta ccacctgggc agcctggcgc tgtccgacct gctcaccctg 720 ctgctggcca tgcccgtgga gctgtacaac ttcatctggg tgcaccaccc ctgggccttc 780 ggcgacgccg gctgccgcgg ctactacttc ctgcgcgacg cctgcaccta cgccacggcc 840 ctcaacgtgg ccagcctgag tgtggagcgc tacctggcca tctgccaccc cttcaaggcc 900 aagaccctca tgtcccgaag ccgcaccaag aagttcatca gcgccatctg gctcgcctcg 960 gccctgctga cggtgcctat gctgttcacc atgggcgagc agaaccgcag cgccgacggc 1020 cagcacgccg gcggcctggt gtgcaccccc accatccaca ctgccaccgt caaggtcgtc 1080 atacaggtca acaccttcat gtccttcata ttccccatgg tggtcatctc ggtcctgaac 1140 accatcatcg ccaacaagct gaccgtcatg gtacgccagg cggccgagca gggccaagtg 1200 tgcacggtcg ggggcgagca cagcacattc agcatggcca tcgagcctgg cagggtccag 1260 gccctgcggc acggcgtgcg cgtcctacgt gcagtggtca tcgcctttgt ggtctgctgg 1320 ctgccctacc acgtgcggcg cctcatgttc tgctacatct cggatgagca gtggactccg 1380 ttcctctatg acttctacca ctacttctac atggtgacca acgcactctt ctacgtcagc 1440 tccaccatca accccatcct gtacaacctc gtctctgcca acttccgcca catcttcctg 1500 gccacactgg cctgcctctg cccggtgtgg cggcgcagga ggaagaggcc agccttctcg 1560 aggaaggccg acagcgtgtc cagcaaccac accctctcca gcaatgccac ccgcgagacg 1620 ctgtactagg ctgtgcgccc cggaacgtgt ccaggaggag cctggccatg ggtccttgcc 1680 cccgacagac agagcagccc ccacccggga gccttgatgg gggtcaggca gaggccagcc 1740 tgcactggag tctgaggcct gggacccccc cctcccaccc cctaacccat gtttctcatt 1800 agtgtctccc gggcctgtcc ccaactcctc cccacccctc ccccatctcc tctttgaaag 1860 ccagaacaag agagcgctcc tctcccagat aggaaaaggg cctctaacaa ggagaaatta 1920 gtgtgcggca aaaggcagtt ttctttgttc tcagactaat ggatggttcc agagaaggaa 1980 atgaaatgtg ctgggtgggg ccgggcctcc ggcggcccgg ctgctgttcc catgtccaca 2040 tctctgaggc ctgcaccccc tctgtctagc tcggggagtc cagccccagt cccgcaggct 2100 ccgtggcttt gggcctcacg tgcagaccct gccatgcaga cccatgcccc cctcccccag 2160 gcagctccaa gaaagctccc tgactcgccc cttcaggcct ggcaagctgg gggcccatcg 2220 ccgtggggag tccctcccac caccctcgcc gcaggcagct gcagccccca gaggggacca 2280 caagcccaaa aaggacaaaa atgggctggc ctggaatggc ccagacccca gcctcccctc 2340 ctccctccca tcctcaccca ggccaaggcc caggggctct gccaggacac cacatgggag 2400 ggggctcagg cctcagcctc aagatcttca gctgtggcct ctcgggctcg gcagaaggga 2460 cgccggatca ggggcctggt ctccagcacc tgcccgagtg gccgtggcca ggatggggtg 2520 cgcattccgt gtgctttgct tgtagctgtg caggctgagg tctggagcca ggcccagagc 2580 tggcttcagg gtggggcctt gagaagggga atgtgggaca ggggcgatgg tgcctggtct 2640 ctgagtaaga tgccaggtcc caggaactca ggcttcaggt gagaaggagc ggtgtgtcca 2700 ggcaccgctg gccggcagcc ctgggctgag gcacagactc atttgtcacc ttctggcggc 2760 ggcagccctg gccccggcct ccaagcagtt gaaaaagctg gcgcctcctt ggtctctagg 2820 atccaggctc cacagagcac atgactagcc aggcccctgg cttaagaagg tcgcctaagc 2880 ctaagagaag acagtcccag gagaagctgg ccgggaccag ccaggagctg ggagccacag 2940 gaagcaaaag tcagcctttt cttcaaggga tttccctgtc tcagagcagc ctttgcccca 3000 gggaaatggg ctctgggctg gctgcctgca ccggccatgt cgacccagga cccggacacc 3060 tggtcttggg ctgtgttcag ccactttgcc ttctctggac tcagtttccc cgtctgagaa 3120 atgagagtcg aatgctacag tatctgcagt cgcttggatc tggctgttga gttgacgggt 3180 tccttgaacc ccacaaaatc cctctccaac cacaggaccc ttcggctcac caagaacggg 3240 gcccagggga gtcaggccta ttcgctgcac ttcctgccaa actttgcccc cacaagcctg 3300 gtcatcagcc aggcagccct cccagtgccc aagggccacc aaccccaggg aaacagggcc 3360 agcacagagg ggccttcctc ccccacagag ctcccatgac atagtctgct ctgggcggaa 3420 gagctttgct gccagccagg gatgtccaga ggtcggtgca gcccctatcc ctgctcagga 3480 gtgggctcag agtctagcaa atgctaaggc ccctcaggct gggctctgaa cgaggacctg 3540 gactcagagc cagacagggc agcctcagac ccttctctgg ggctcctgga ccttgggcca 3600 taatttctga gcctcggttt ccccatctaa ggaacagatg tggtcgttcc gccctctcag 3660 ctggatgaga ctgtcctgga ggatccaccc cggaacagac agaacggtgt ctctcaggat 3720 ggtgctctga gagagggcag agtggatgcc ccactgccct agaccctcgg tagacgtggg 3780 gtctctgggg cggggtctgt ggctgtgact gaagtcggct ttcccgttga tgtcttgatg 3840 ctcctatctg tgcacttacc gtaggtaggg acacgtgtcc atgcaccaca gacacaccca 3900 cgacacctga tctcgtatca ctagcttgcg gccaggtcat gatgtggccc cggaagctgg 3960 ccctgcgtgc catgagtgcg tcggtcatgg agtccggagc ccctgagccg gcccctggtg 4020 acggcacagc cctcacagct caaacgccca cccccactcc caccatctgc aggtggtgaa 4080 aacaaacccc gtgtatctct caataaaggt ggccgaaggg cctcgatgtg g 4131 <210> 62 <211> 3536 <212> DNA <213> HUMAN <400> 62 tgaagtctct tcccaagcaa atgggagctt ctttggacct tggagcacac agaggattct 60 actttcttta aaactttgtt ttcaggcaat ttccctgaga accgtttact tccagaagat 120 tggtggagct tgatctgaag gctggccatg aaatctcaag gtcaacattg gtattccagt 180 tcagataaaa actgtaaagt gagctttcgt gagaagcttc tgattattga ttcaaacctg 240 ggggtccaag atgtggagaa cctcaagttt ctctgcatag gattggtccc caacaagaag 300 ctggagaagt ccagctcagc ctcagatgtt tttgaacatc tcttggcaga ggatctgctg 360 agtgaggaag accctttctt cctggcagaa ctcctctata tcatacggca gaagaagctg 420 ctgcagcacc tcaactgtac caaagaggaa gtggagcgac tgctgcccac ccgacaaagg 480 gtttctctgt ttagaaacct gctctacgaa ctgtcagaag gcattgactc agagaactta 540 aaggacatga tcttccttct gaaagactcg cttcccaaaa ctgaaatgac ctccctaagt 600 ttcctggcat ttctagagaa acaaggtaaa atagatgaag ataatctgac atgcctggag 660 gacctctgca aaacagttgt acctaaactt ttgagaaaca tagagaaata caaaagagag 720 aaagctatcc agatagtgac acctcctgta gacaaggaag ccgagtcgta tcaaggagag 780 gaagaactag tttcccaaac agatgttaag acattcttgg aagccttacc gagggcagct 840 gtgtacagga tgaatcggaa ccacagaggc ctctgtgtca ttgtcaacaa ccacagcttt 900 acctccctga aggacagaca aggaacccat aaagatgctg agatcctgag tcatgtgttc 960 cagtggcttg ggttcacagt gcatatacac aataatgtga cgaaagtgga aatggagatg 1020 gtcctgcaga agcagaagtg caatccagcc catgccgacg gggactgctt cgtgttctgt 1080 attctgaccc atgggagatt tggagctgtc tactcttcgg atgaggccct cattcccatt 1140 cgggagatca tgtctcactt cacagccctg cagtgcccta gactggctga aaaacctaaa 1200 ctctttttca tccaggcctg ccaaggtgaa gagatacagc cttccgtatc catcgaagca 1260 gatgctctga accctgagca ggcacccact tccctgcagg acagtattcc tgccgaggct 1320 gacttcctac ttggtctggc cactgtccca ggctatgtat cctttcggca tgtggaggaa 1380 ggcagctggt atattcagtc tctgtgtaat catctgaaga aattggtccc aagacatgaa 1440 gacatcttat ccatcctcac tgctgtcaac gatgatgtga gtcgaagagt ggacaaacag 1500 ggaacaaaga aacagatgcc ccagcctgct ttcacactaa ggaaaaaact agtattccct 1560 gtgcccctgg atgcactttc aatatagcag agagtttttg ttggttctta gacctcaaac 1620 gaatcattgg gtataacctc cagcctcctg cccagcacag gaatcggtgg tctccacctg 1680 tcattctaga aacaggaaac accgtgtttt ctgacacagt caattctgat tttctttttc 1740 ttttgcaagt ctaaatgtta gaaaactttc tttttttgga gatagtctca ttctgtcacc 1800 cagactggag tgcagggggg caatcacggc tcactgtagt ctcgacctcc caggctcaag 1860 ctgtcctccc acctcagcct cccaagtagc tgagactaca ggtgtgtgtc catgcacagc 1920 taacttttta ttttttttgt ggagatgggg tttcactatg ttgcctaagc tggtctcaaa 1980 ctcctgggct caagcgatcc tcccacctca gcttctcaaa gttctgggac tacaggcatg 2040 aaatactgtg cctggcctgg ggaccaggtg cattttaagg ttccttggtg ttcaaaaacc 2100 acgttcttag cctagattga gcttagattg cctctctaga caactacccc ttagttataa 2160 ttctgtgtcc cctctgcatg cccttaaaca ttggacagtg aggtcacagt ccacccaccc 2220 tctctctgat ctcccccttc ctaagacttc tcttttgcac atctagtgag gtgaaaattt 2280 ggtctatgcc aggcccattt cctgcttttg tgtaaggaag gtgctcacat aggaagtttt 2340 tatttggtta gagacaggtt tccctgtagg aagatgatgg ctcatttaca ctcagctgct 2400 ctgcaagcag aaactttaca acctgatgtc atattccatt ttggactggg tgcggtgact 2460 catgcctgta atcccagtac tctgggaagc caaggcaggc agatcacttg aggtcaggag 2520 ttcgagacca gcctggccaa tacggcaaaa cctcatcatt actaaaaaca caaaaattag 2580 ccaggtgtgg cggcgagcac ctgtaatccc agctactcgg gaggctgaga caggagaatc 2640 tcttgaatcc aggaggcaga ggctgtggtg agccaagatg acacaactgc actccagctt 2700 gggcaacagg gcgagacctt gtttaaaaaa aaaattcaat attggggttg gaacatttca 2760 gttgccattg acagaacacc caattcaaat tgactgaagc aaagaaggga atttattgcc 2820 tctttcacat tgaaacccag gagtggataa cactggcttc aggcaaagct tgaatcagga 2880 ctcaatctac aggccagcac ctttctcttg gccggatgtc ctcagggctg gcagatgcag 2940 tagactgcag tggacagtcc ccaccttgtt actgctacta cactttgctc ctctggccca 3000 aggcatgagg agagaggctg tgtcagaaac tgaagctgtt ctcaggatca ctgggctctt 3060 cttggcagag gggatgtctg gcttgcctga agggagtggc tctgtaagga cgccttgatg 3120 ctttcttcat taagattttg agcattttta cgtacttgag cttttttttt tttttttttc 3180 aatttctaga ggaacttttt ctctgttaat tcctggaact gtattttgaa tccttaaagg 3240 tgagccctca tagggagatc caaagtcctg tggttaacgc cttcatttat agatgaggca 3300 gctgaggcct ggggatgtga acaacctgct cacagtcctc atttactgga tttgacttca 3360 gccaggtgaa ctggaatgcc ttggggcgtg gaagggcatt aggagtgttt catttgatat 3420 gtgaatgctc ataaaaaaat gtcaaggaat gaagaacaac aactctcagt ggtgcctgca 3480 tttataatta tttatgtgaa agtcaaattc atgtacagta aatttgttat aagaat 3536 <210> 63 <211> 2040 <212> DNA <213> HUMAN <400> 63 cacgaggaga acagaagaag agaaagctca gcaaattttc ttgccatact tcatgacttc 60 actgtggcta agtgtgggga ccagacagga ctcgtggaga catccaggtg ctgaagcctt 120 cagctactgt ctcagttttt tgaagtttag caatggcgtc tttctctgct gagaccaatt 180 caactgacct actctcacag ccatggaatg agcccccagt aattctctcc atggtcattc 240 tcagccttac ttttttactg ggattgccag gcaatgggct ggtgctgtgg gtggctggcc 300 tgaagatgca gcggacagtg aacacaattt ggttcctcca cctcaccttg gcggacctcc 360 tctgctgcct ctccttgccc ttctcgctgg ctcacttggc tctccaggga cagtggccct 420 acggcaggtt cctatgcaag ctcatcccct ccatcattgt cctcaacatg tttgccagtg 480 tcttcctgct tactgccatt agcctggatc gctgtcttgt ggtattcaag ccaatctggt 540 gtcagaatca tcgcaatgta gggatggcct gctctatctg tggatgtatc tgggtggtgg 600 cttgtgtgat gtgcattcct gtgttcgtgt accgggaaat cttcactaca gacaaccata 660 atagatgtgg ctacaaattt ggtctctcca gctcattaga ttatccagac ttttatggag 720 atccactaga aaacaggtct cttgaaaaca ttgttcagcc gcctggagaa atgaatgata 780 ggttagatcc ttcctctttc caaacaaatg atcatccttg gacagtcccc actgtcttcc 840 aacctcaaac atttcaaaga ccttctgcag attcactccc taggggttct gctaggttaa 900 caagtcaaaa tctgtattct aatgtattta aacctgctga tgtggtctca cctaaaatcc 960 ccagtgggtt tcctattgaa gatcacgaaa ccagcccact ggataactct gatgcttttc 1020 tctctactca tttaaagctg ttccctagcg cttctagcaa ttccttctac gagtctgagc 1080 taccacaagg tttccaggat tattacaatt taggccaatt cacagatgac gatcaagtgc 1140 caacacccct cgtggcaata acgatcacta ggctagtggt gggtttcctg ctgccctctg 1200 ttatcatgat agcctgttac agcttcattg tcttccgaat gcaaaggggc cgcttcgcca 1260 agtctcagag caaaaccttt cgagtggccg tggtggtggt ggctgtcttt cttgtctgct 1320 ggactccata ccacattttt ggagtcctgt cattgcttac tgacccagaa actcccttgg 1380 ggaaaactct gatgtcctgg gatcatgtat gcattgctct agcatctgcc aatagttgct 1440 ttaatccctt cctttatgcc ctcttgggga aagattttag gaagaaagca aggcagtcca 1500 ttcagggaat tctggaggca gccttcagtg aggagctcac acgttccacc cactgtccct 1560 caaacaatgt catttcagaa agaaatagta caactgtgtg aaaatgtgga gcagccaaca 1620 agcaggggct cttaggcaat cacatagtga aagtttataa gaggatgaag tgatatggtg 1680 agcagcggac ttcaaaaact gtcaaagaat caatccagcg gttctcaaac ggtacacaga 1740 ctattgacat cagcatcacc tagaaacttg ttagaaatgc aaattctcaa gccgcatccc 1800 agacttgctg aatcggaatc tctgggggtt gggacccagc aagggcactt aacaaacccc 1860 cgtttctgat taatgctaaa tgtaagaatc attgtaaaca ttagttctat ttctatccca 1920 aactaagcta tgtgaaataa gagaagctac tttgttttta aatgatgttg aatatttgtc 1980 gatatttcca tcattaaatt tttccttagc attgtctaag tcaaaaaaaa aaaaaaaaaa 2040 <210> 64 <211> 3923 <212> DNA <213> HUMAN <400> 64 gagccagcga gccagcgcgc gcgggcgggc ggacagatcg gagccgagcg gggccgggcg 60 gggcgctccc tgcagggctc tgcgcggcgt gccgcggcgg ccgcgggctc cggccccggg 120 ccatgagccc ctccgcgact cggcgctgag cccgccaccg gtccagcgcc ccaggacccg 180 ccgccggctg ccggcttgcc gaagccccct caggatcccc tcaacaagga tggaactgaa 240 ggccgaggag gaggaggtgg gtggcgtcca gccggtgagc atccaggcct tcgccagcag 300 ctccacactg cacggcctgg cccacatctt ctcctacgag cggctgtctc tgaagcgggc 360 actgtgggcc ctgtgcttcc tgggctcgct ggctgtgctg ctgtgtgtgt gcacggagcg 420 tgtgcagtac tacttccact accaccatgt caccaagctc gacgaggtgg ctgcctctca 480 gcttaccttc cctgctgtca cgctgtgcaa cctcaacgag ttccgcttta gccaagtctc 540 caagaatgac ctgtatcatg ctggggagct gctggccctg ctcaacaaca ggtatgagat 600 accagacaca cagatggcag atgaaaagca gctggagata ctgcaggaca aagccaactt 660 ccgcagcttc aaacccaaac ccttcaacat gcgtgagttc tacgaccgag ctgggcacga 720 cattcgagac atgctgctct cctgccactt ccggggggag gtctgcagcg ctgaagactt 780 caaggtggtc ttcacacgct atggaaagtg ctacacgttc aactcgggcc gagatgggcg 840 gccgcggctg aagaccatga aggatgggac gggcaatggg ctggaaatca tgctggacat 900 ccagcaggac gagtacctgc ctgtgtgggg ggagactgac gagacgtcct tcgaagcagg 960 catcaaagtg cagatccata gtcaggatga acctcctttc atcgaccagc tgggctttgg 1020 cgtggcccca ggcttccaga cctttgtggc ctgccaggag cagcggctca tctacctgcc 1080 cccaccctgg ggcacctgca aagctgttac catggactcg gatttggatt tcttcgactc 1140 ctacagcatc actgcctgcc gcatcgactg tgagacgcgc tacctggtgg agaactgcaa 1200 ctgccgcatg gtgcacatgc caggggatgc cccatactgt actccagagc agtacaagga 1260 gtgtgcagat cctgctctgg acttcctggt ggagaaggac caggagtact gcgtgtgtga 1320 aatgccttgc aacctgaccc gctatggcaa agagctgtcc atggtcaaga tccccagcaa 1380 agcctcagcc aagtacctgg ccaagaagtt caacaaatct gagcaataca taggggagaa 1440 catcctggtg ctggacattt tctttgaagt cctcaactat gagaccattg aacagaagaa 1500 ggcctatgag attgcagggc tcctgggtga gctgctgatg acacctgtcc ccttctcatg 1560 ccatgggcat ggcgtggctc cctatcatcc aaaagcaggg tgctcacttc tgtcccatga 1620 gggtcctcca ccccagaggc ccttccccaa accctgttgt cttggtgaca tcgggggcca 1680 gatggggctg ttcatcgggg ccagcatcct cacggtgctg gagctctttg actacgccta 1740 cgaggtcatt aagcacaagc tgtgccgacg aggaaaatgc cagaaggagg ccaaaaggag 1800 cagtgcggac aagggcgtgg ccctcagcct ggacgacgtc aaaagacaca acccgtgcga 1860 gagccttcgg ggccaccctg ccgggatgac atacgctgcc aacatcctac ctcaccatcc 1920 ggcccgaggc acgttcgagg actttacctg ctgagccccg caggccgctg aaccaaaggc 1980 ctagatgggg aggactagga gagcgrgggg gcccccagct gcctcctcac atctgccctg 2040 ggractcccc acactccggg gcagatcttt cctcttgtct gtggtaagga aggagtcttg 2100 accatagagt cctctctctg cctctatccc attcytttta catttaacaa aactaatcta 2160 aaaaagaact aaaaagggag aacggggcaa gggacctcag gctgcccctc tctcctccat 2220 gctgcctccc ctagctccca gcctgaattc tgtctatcta gctgtctgcc atctgagtgt 2280 ccatctacat tctgctgcca ccagtcacca aaggcccttc ccagtgaggg gtggaaggga 2340 tctctggggt ctggaatttg gccccaaacc agagaatgta ccttaagggg gagggctagt 2400 gtgggggagg gaggcttccc cagccttaag agaccctctc agcccagtga ctgtccccaa 2460 acccaagtct cctggcagga actaaaacct cagccccact ctctcacacc atgtggaatc 2520 tcgtgggggt cggggatccc cttaagaagt ggtaatgggg acaagatgcg gccctggtgc 2580 tgtaggctac atcctgatac ctataagttc acccccaccc cacagctgct ggagagaaat 2640 cccaagaggc agcccttcct caccatccca ttaaagacck ggctggttag cgtccagctc 2700 agggagaagg gcgctagtgc ctaacctcac tggtccctct cccggaggcc cttgtagagg 2760 gccacgtcca taaattttct tatggaactc tcccacatcc tcttccccaa cttcatttgc 2820 ttctctcaac aacctcatct gcattttcta tttctatatg atacagactc tatattgcta 2880 tatctctgta tatactttcc cagccctgtc tgtctccacc ccatcccctc ttgtctctga 2940 gaaccattct cccaccccaa gttccacctt ctatgtttct actccctccc tggtctctga 3000 atgccttygc ctgtataaag agttggactc tctcccctgg tgtctgtact gtgtacacac 3060 atccctctga gaagcacaag gagacgacac gcgcattgta acctttgcac tgtctcagtg 3120 gcgacaaagg aagctgtgaa tcacaagctc tgcctctttc tggcctcacc ctctccccca 3180 acccgggcac cctcggccct ccctgcagcc ttaacattct cttcccctgc tcctcctatc 3240 ccattgccct ctgcccagct gacagtggca tccccaggga aggggttgct gtagagatag 3300 cccccaccca ggggatggag gtctaccctg gacactaagc caagtgtgtc agagacagaa 3360 gggagctggg gattggcgac tcctgaagtt ggggcagtgg gatgctgaca ggcagaagct 3420 gaggtcctca gtcagtggcc tttcctcctt ctgggtgccc agcccccttt cctcacctga 3480 tacccaagcc caccactttt attttctggt gaggtgggtt tgggaggaaa gagaggccta 3540 gaggaggagt tgaaagctct gctgttgtct caccctatct taatgagaga caagtgaggt 3600 ggagggcctg ccccccctcc ctccaccaga cactccttcc aggcctgagc cccaacccct 3660 cttcaggcct tccttcccta gctgtgtctt ggtcttcaat cccagaacag gacctgtgag 3720 cagctgcatt ggcctggagc tggagagtaa ggctgtagga tctttggaat ctcttggttc 3780 ctaagagttt cctcagagat catacctccc cagagggaag caggaatgag gccaaaaagt 3840 gtgcattgga taggggaaca gcaggcaggg ctctgggtga cgcatgcctc tggtctaata 3900 aactgggttt caaccaaaaa aaa 3923 <210> 65 <211> 2832 <212> DNA <213> HUMAN <400> 65 gcgagctgac agccgccgcc gccgccgcct ccgcccacct tcctcgccgg ggcttcgtct 60 ttcactcctt cgggctgcct ccccctcccc ttgtcccctg ccccttgccc tgcttctgca 120 gaagatttca acactacact tgcacaatgt ctttgaaacc aagagtagta gattttgatg 180 aaacatggaa caaacttttg acgacaataa aagccgtggt catgttggaa tacgtcgaaa 240 gagcaacatg gaatgaccgt ttctcagata tctatgcttt atgtgtggcc tatcctgaac 300 cccttggaga aagactttat acagaaacta agattttttt ggaaaatcat gttcggcatt 360 tgcataagag agttttggag tcagaagaac aagtacttgt tatgtatcat aggtactggg 420 aagaatacag caagggtgca gactatatgg actgcttata taggtatctc agcacccagt 480 ttattaaaaa gaataaatta acagaagcgg accttcagta tggctatggt ggtgtagata 540 tgaatgaacc acttatggaa ataggagagc tagcattgga tatgtggagg aaattgatgg 600 ttgaaccact tcaggccatc cttatccgaa tgctgctccg agaaatcaaa aatgatcgtg 660 gtggagaaga cccaaaccag aaagtaatcc atggggttat taactccttt gttcatgttg 720 aacagtataa gaaaaaattc cccttaaagt tttatcagga aatttttgag tctccctttc 780 tgactgaaac aggagagtat tacaaacaag aagcttcaaa tttattacaa gaatcaaact 840 gctcacagta tatggaaaag gttttaggta gattaaaaga tgaagaaatt cgatgtcgaa 900 aatacctaca tccaagttca tatactaagg tgattcatga atgtcaacaa cgaatggtag 960 cagaccactt acagttttta catgcagaat gtcataatat aattcgacaa gagaaaaaaa 1020 atgacatggc aaatatgtac gtcttactcc gtgctgtgtc cactggttta cctcatatga 1080 ttcaggagct gcaaaaccac atccatgatg agggccttcg agcaaccagc aaccttactc 1140 aggaaaacat gccaacacta tttgtggagt cagttttgga agtgcatggt aaatttgttc 1200 agcttatcaa cactgttttg aatggtgatc agcattttat gagtgcgttg gataaggccc 1260 ttacgtcagt tgtaaattac agagaaccta agtctgtttg caaagcacct gaactgcttg 1320 ctaagtactg tgacaactta ctgaagaagt cagcgaaagg gatgacagag aatgaagtgg 1380 aagacaggct tacgagcttc atcacagtgt tcaaatacat tgatgacaag gacgtctttc 1440 aaaagttcta cgcaagaatg ctggcaaaac gtttaattca tgggttatcc atgtctatgg 1500 actctgaaga agccatgatc aacaaattaa agcaagcctg tggttatgag tttaccagca 1560 agctacatcg gatgtataca gatatgagtg tcagcgctga tctcaacaat aagttcaaca 1620 attttatcaa aaaccaagac acagtaatag atttgggaat tagttttcaa atatatgttc 1680 tacaggctgg tgcgtggcct cttactcagg ctccttcatc tacgtttgca attccccagg 1740 aattagaaaa aagtgtacag atgtttgaat tattttatag ccaacatttc agtggaagga 1800 aacttacatg gttacattat ctgtgtacag gtgaagttaa aatgaactat ttgggcaaac 1860 catatgtagc catggttaca acataccaaa tggcagttct tcttgccttt aacaacagtg 1920 aaactgtcag ttataaagag cttcaggaca gcactcagat gaatgaaaag gaactgacaa 1980 aaacaatcaa atcattactt gatgtgaaaa tgattaacca tgattcagaa aaggaagata 2040 ttgatgcaga atcttcgttt tcattaaata tgaactttag cagtaaaaga acaaaattta 2100 aaattactac atcaatgcag aaagacacac cacaagaaat ggagcagact agaagtgcag 2160 ttgatgagga ccggaaaatg tatctccaag ctgctatagt tcgtatcatg aaagcacgaa 2220 aagtgcttcg gcacaatgcc cttattcaag aggtgattag ccagtcaaga gctaggttta 2280 atcccagtat cagcatgatt aagaagtgta ttgaagttct gatagacaaa caatacatag 2340 aacgcagcca ggcgtcggca gatgaataca gctacgtcgc gtgatgtcgc tctcctccag 2400 cgtggtgtga gaagatcatt gccatcacca tttggtgtgt tcctgtggga aaaagcagga 2460 ctgtgcctcc ataatttggt catttggcag cccctgtttt ctgctgttta caacatcacc 2520 agtgccacgt catgagcgtc aaagaaaatg cctagagata tttcaagctc atgacattat 2580 gacatttctt aaaactttat taaaagaatg agtgaagtat tgctgaaaag tggaaaatcg 2640 gttgggtacc atgctttttc tccccttcac gtttgcagtt gatgtgtctt tttttttttt 2700 tttaatgtat cttaaaggac ataaaattta aaaacttaaa tattgtaata tgacagataa 2760 cctaataatt gtatctacat taaaatgaca aacatgatac tgctgcttgt caaataaaaa 2820 aaaaaaaaaa aa 2832 <210> 66 <211> 2029 <212> DNA <213> HUMAN <400> 66 atattgtgct tccaccactg ccaataacaa aataactagc aaccatgaag tgggtggaat 60 caattttttt aattttccta ctaaatttta ctgaatccag aacactgcat agaaatgaat 120 atggaatagc ttccatattg gattcttacc aatgtactgc agagataagt ttagctgacc 180 tggctaccat attttttgcc cagtttgttc aagaagccac ttacaaggaa gtaagcaaaa 240 tggtgaaaga tgcattgact gcaattgaga aacccactgg agatgaacag tcttcagggt 300 gtttagaaaa ccagctacct gcctttctgg aagaactttg ccatgagaaa gaaattttgg 360 agaagtacgg acattcagac tgctgcagcc aaagtgaaga gggaagacat aactgttttc 420 ttgcacacaa aaagcccact ccagcatcga tcccactttt ccaagttcca gaacctgtca 480 caagctgtga agcatatgaa gaagacaggg agacattcat gaacaaattc atttatgaga 540 tagcaagaag gcatcccttc ctgtatgcac ctacaattct tctttgggct gctcgctatg 600 acaaaataat tccatcttgc tgcaaagctg aaaatgcagt tgaatgcttc caaacaaagg 660 cagcaacagt tacaaaagaa ttaagagaaa gcagcttgtt aaatcaacat gcatgtgcag 720 taatgaaaaa ttttgggacc cgaactttcc aagccataac tgttactaaa ctgagtcaga 780 agtttaccaa agttaatttt actgaaatcc agaaactagt cctggatgtg gcccatgtac 840 atgagcactg ttgcagagga gatgtgctgg attgtctgca ggatggggaa aaaatcatgt 900 cctacatatg ttctcaacaa gacactctgt caaacaaaat aacagaatgc tgcaaactga 960 ccacgctgga acgtggtcaa tgtataattc atgcagaaaa tgatgaaaaa cctgaaggtc 1020 tatctccaaa tctaaacagg tttttaggag atagagattt taaccaattt tcttcagggg 1080 aaaaaaatat cttcttggca agttttgttc atgaatattc aagaagacat cctcagcttg 1140 ctgtctcagt aattctaaga gttgctaaag gataccagga gttattggag aagtgtttcc 1200 agactgaaaa ccctcttgaa tgccaagata aaggagaaga agaattacag aaatacatcc 1260 aggagagcca agcattggca aagcgaagct gcggcctctt ccagaaacta ggagaatatt 1320 acttacaaaa tgcgtttctc gttgcttaca caaagaaagc cccccagctg acctcgtcgg 1380 agctgatggc catcaccaga aaaatggcag ccacagcagc cacttgttgc caactcagtg 1440 aggacaaact attggcctgt ggcgagggag cggctgacat tattatcgga cacttatgta 1500 tcagacatga aatgactcca gtaaaccctg gtgttggcca gtgctgcact tcttcatatg 1560 ccaacaggag gccatgcttc agcagcttgg tggtggatga aacatatgtc cctcctgcat 1620 tctctgatga caagttcatt ttccataagg atctgtgcca agctcagggt gtagcgctgc 1680 aaacgatgaa gcaagagttt ctcattaacc ttgtgaagca aaagccacaa ataacagagg 1740 aacaacttga ggctgtcatt gcagatttct caggcctgtt ggagaaatgc tgccaaggcc 1800 aggaacagga agtctgcttt gctgaagagg gacaaaaact gatttcaaaa actcgtgctg 1860 ctttgggagt ttaaattact tcaggggaag agaagacaaa acgagtcttt cattcggtgt 1920 gaacttttct ctttaatttt aactgattta acactttttg tgaattaatg aaatgataaa 1980 gacttttatg tgagatttcc ttatcacaga aataaaatat ctccaaatg 2029 <210> 67 <211> 1438 <212> DNA <213> HUMAN <400> 67 gggctgcagt gagccaaaag catgccattg cactccagct tgggcaacag agtgagaccc 60 tgtctcaaaa aaaagaaaaa ataatactat gtctggtcca taacctgaaa tatttttatc 120 ttcacgttcc ttatcattca ctgaactttt atttttcttt taaaattttt tcctttcttt 180 ttaaatttgc ttctacagat ttcttcattc tccatttagc aaggtcatgg aagatttgga 240 ggaaacatta tttgaagaat ttgaaaacta ttcctatgac ctagactatt actctctgga 300 gtctgatttg gaggagaaag tccagctggg agttgttcac tgggtctccc tggtgttata 360 ttgtttggct tttgttctgg gaattccagg aaatgccatc gtcatttggt tcacggggct 420 caagtggaag aagacagtca ccactctgtg gttcctcaat ctagccattg cggatttcat 480 ttttcttctc tttctgcccc tgtacatctc ctatgtggcc atgaatttcc actggccctt 540 tggcatctgg ctgtgcaaag ccaattcctt cactgcccag ttgaacatgt ttgccagtgt 600 ttttttcctg acagtgatca gcctggacca ctatatccac ttgatccatc ctgtcttatc 660 tcatcggcat cgaaccctca agaactctct gattgtcatt atattcatct ggcttttggc 720 ttctctaatt ggcggtcctg ccctgtactt ccgggacact gtggagttca ataatcatac 780 tctttgctat aacaattttc agaagcatga tcctgacctc actttgatca ggcaccatgt 840 tctgacttgg gtgaaattta tcattggcta tctcttccct ttgctaacaa tgagtatttg 900 ctacttgtgt ctcatcttca aggtgaagaa gcgaacagtc ctgatctcca gtaggcattt 960 ctggacaatt ctggttgtgg ttgtggcctt tgtggtttgc tggactcctt atcacctgtt 1020 tagcatttgg gagctcacca ttcaccacaa tagctattcc caccatgtga tgcaggctgg 1080 aatccccctc tccactggtt tggcattcct caatagttgc ttgaacccca tcctttatgt 1140 cctaattagt aagaagttcc aagctcgctt ccggtcctca gttgctgaga tactcaagta 1200 cacactgtgg gaagtcagct gttctggcac agtgagtgaa cagctcagga actcagaaac 1260 caagaatctg tgtctcctgg aaacagctca ataagttatt acttttccac aaatcagtat 1320 atggcttttt atgtgggtcc tctgactgat gctttcagat taaaattgtt tccaagatag 1380 agagccgact ccactttcat agttattgtt tctggtcaca tatatggcat cacatttt 1438 <210> 68 <211> 1350 <212> DNA <213> HUMAN <400> 68 cgccactgcc acccctccca gactgtggac gggaggatgg agtcgatggc cgtcgctacc 60 gacggcgggg agaggccggg ggtcccagcg ggctcaggtc tgtcggcttc ccagcgtcgg 120 gcggagctgc gtcggagaaa gctgctcatg aactcggaac agcgcatcaa ccggatcatg 180 ggctttcaca ggcccgggag cggcgcggaa gaagaaagtc aaacaaaatc aaagcagcag 240 gacagtgata aactgaactc cctcagcgtt ccttccgttt caaagcgagt agtgctgggt 300 gattcagtca gtacaggaac aactgaccag cagggtggtg tggccgaggt aaaggggacc 360 caactgggag acaaattgga ctcgttcatt aaaccacctg agtgcagtag tgatgtcaac 420 cttgagctcc ggcagcggaa cagaggggac ctgacagcgg actcggtcca gaggggttcc 480 cgccatggcc tagagcagta cctttccaga ttcgaagaag caatgaagct aaggaaacag 540 ctgattagtg aaaaacccag tcaagaggat ggaaatacaa cagaagaatt tgactctttt 600 cgaatattta gattggtggg atgtgctctt cttgctcttg gagtcagagc ttttgtttgc 660 aaatacttgt ccatatttgc tccatttctt actttacaac ttgcgtacat gggattatac 720 aaatattttc ccaagagtga aaagaagata aagacaacag tactaacagc tgcacttcta 780 ttgtcgggaa ttcctgccga agtgataaat cgatcaatgg atacctatag caaaatgggc 840 gaagtcttca cagatctctg tgtctacttt ttcactttta tcttttgtca tgaactgctt 900 gattattggg gctctgaagt accatgaagc ctgtagaact gagaaggaga agcttacgaa 960 aaaaatcctc ttctatattg cagtgtctct aaaggaggca aattggttta caccttcatg 1020 taattctttt actttagggg ttgtaaagct actttattag atatagaatg gcagattctc 1080 tgatttaaaa gggctgagtt tgtattatta ctgatatgaa gaatagagta ccaatgtcat 1140 taattgattt ttcttgttaa tcagaattcc tattctgtac ctttcctcta acttctcaga 1200 tttgtaattc ttcttttcgg gagctgagct agtgctttta ggagaacaga taaatgtggt 1260 ctcagccagc cctagagact gcttcttgtg tttgtgtcat tctgtcctga gaaatgaagt 1320 catctgaaaa ataaaaatgc agaaacccaa 1350 <210> 69 <211> 1313 <212> DNA <213> HUMAN <400> 69 atgagctcgg cctcggggct ccgcaggggg cacccggcag tgtcaactgt tagccacgca 60 gatgccgatt gctttgtgtg tgtcttcctg agccatggcg aaggcaatca catttatgca 120 tatgatgcta aaatcgaaat tcagacatta actggcttgt tcaaaggaga caagtgtcac 180 agcctggttg gaaaacccaa gatatttatc atccaggcat gtcggggaaa ccagcacgat 240 gtgccagtca ttcctttgga tgtagtagat aatcagacag agaagttgga caccaacata 300 actgaggtgg atgcagcctc cgtttacacg ctgcctgctg gagctgactt cctcatgtgt 360 tactctgttg cagaaggata ttattctcac cgggaaactg tgaacggctc atggtacatt 420 caagatttgt gtgagatgtt gggaaaatat ggctcctcct tagagttcac agaactcctc 480 acactggtga acaggaaagt ttctcagcgc cgagtggact tttgcaaaga cccaagtgca 540 attggaaaga agcaggttcc ctgttttgcc tcaatgctaa ctaaaaagct gcatttcttt 600 ccaaaatcta attaattaat agaggctatc taatttcaca ctctgtattg aaaatggctt 660 tctcagccag gcgtggttac tcacacctgt aatcccagca ctttgggagt ccaaggtggg 720 cggatcacct gaggtcggga gttcgagacc agcctgacca acatggcaga agccccgcct 780 ctactaaaaa tgcaaaaaaa aatttagcta ggcatggcgg cgcatgcctg caatcccagc 840 tacttggaag gctgaggcag gagaatcact tgaacccagg aggtggaggc tgcggtgagc 900 cgagcattgc gccattgcac tccagcctgg gcaacgagtg aaactccgtc tcaaaaaaaa 960 agaaaatgtc tttctcttcc ttttatataa atatcgttag ggtgaagcat tatggtctaa 1020 tgattcaaat gttttaaagt ttaatgccta gcagagaact gccttaaaaa aaaaaagttc 1080 atgttggcca tggtgaaagg gtttgatatg gagaaacaaa atcctcagga aattagataa 1140 atagaaattt ataagcattt gtattatttt ttaataaact gcagggttac accaaaatct 1200 agctgattta acttgtattt tgtcactttt ttataaaagt ttattgtttg atgtttttaa 1260 aggtttttga aatccaggaa ttaaatcatc ccttaataaa atattcgaaa ttc 1313 <210> 70 <211> 2641 <212> DNA <213> HUMAN <400> 70 ggccggtggc ccgggcccga ccaccccagc tgcgcgtcgt tactggccac aagtttgctc 60 tgggccagcc aagttggcaa cttggaagct tctcccgggc tctggaggag ggtccctgct 120 tcttcctaca gccgttccgg gcatggccgg gctgggggcg tcgctccacg tctggggttg 180 gctaatgctc ggcagctgcc tcctggccag agcccagctg gattctgatg gcaccattac 240 tatagaggag cagattgtcc ttgtgctgaa agcgaaagta caatgtgaac tcaacatcac 300 agctcaactc caggagggag aaggtaattg tttccctgaa tgggatggac tcatttgttg 360 gcccagagga acagtgggga aaatatcggc tgttccatgc cctccttata tttatgactt 420 caaccataaa ggagttgctt tccgacactg taaccccaat ggaacatggg attttatgca 480 cagcttaaat aaaacatggg ccaattattc agactgcctt cgctttctgc agccagatat 540 cagcatagga aagcaagaat tctttgaacg cctctatgta atgtataccg ttggctactc 600 catctctttt ggttccttgg ctgtggctat tctcatcatt ggttacttca gacgattgca 660 ttgcactagg aactatatcc acatgcactt atttgtgtct ttcatgctga gagctacaag 720 catctttgtc aaagacagag tagtccatgc tcacatagga gtaaaggagc tggagtccct 780 aataatgcag gatgacccac aaaattccat tgaggcaact tctgtggaca aatcacaata 840 tatcgggtgc aagattgctg ttgtgatgtt tatttacttc ctggctacaa attattattg 900 gatcctggtg gaaggtctct acctgcataa tctcatcttt gtggctttct tttcggacac 960 caaatacctg tggggcttca tcttgatagg ctgggggttt ccagcagcat ttgttgcagc 1020 atgggctgtg gcacgagcaa ctctggctga tgcgaggtgc tgggaactta gtgctggaga 1080 catcaagtgg atttatcaag caccgatctt agcagctatt gggctgaatt ttattctgtt 1140 tctgaatacg gttagagttc tagctaccaa aatctgggag accaatgcag ttgggcatga 1200 cacaaggaag caatacagga aactggccaa atcgacactg gtcctggtcc tagtctttgg 1260 agtgcattac atcgtgttcg tatgcctgcc tcactccttc actgggctcg ggtgggagat 1320 ccgcatgcac tgtgagctct tcttcaactc ctttcagggt ttctttgtgt ctatcatcta 1380 ctgctactgc aatggagagg ttcaggcaga ggtgaagaag atgtggagtc ggtggaatct 1440 ctccgtggac tggaaaagga caccgccatg tggcagccgc agatgcggct cagtgctcac 1500 caccgtgacg cacagcacca gcagccagtc acaggtggcg gccagcacac gcatggtgct 1560 tatctctggc aaagctgcca agatcgccag cagacagcct gacagccaca tcactttacc 1620 tggctatgtc tggagtaact cagagcagga ctgcctgcca cactctttcc acgaggagac 1680 caaggaagat agtgggaggc agggagatga tattctaatg gagaagcctt ccaggcctat 1740 ggaatctaac ccagacactg aaggatgcca aggagaaact gaggatgttc tctgaatgga 1800 catttgtggc tgactttcat gggctggtcc aatggctggt tgtgtgagag ggcttggctg 1860 atactcctat gcttgagttc aaaggctgaa aattcagtta aggtgttact taataatagt 1920 ttttaggctc catgaattgg ctcctgtaaa tactaacgac atgaaaatgc aagtgtcaat 1980 ggagtagttt attaccttct attggcatca agttttcctc taaattaatg tatggtattt 2040 gctctgtgat tgttcatttt tttctgctac ttttgggtag aaaaaagatt caattgcttg 2100 gctgtagctt tctctcatat atatcaccct aaatataatg aagatctttt agtgtgtatc 2160 attttccttt tagaaactag tattctctta tttcttactt taatgtactt ctatcactgc 2220 atttattttg cctgtgcata ggagcaatta ggatctaaaa aaatatatgg gaagataaaa 2280 gatctaagaa caagtacttg ctggaaaatt agttggctgg acattgataa aataatgcat 2340 ttataacaat tacatgtgtt tttgggaaca aggaaaattt ctcaaaaaag aatatttcac 2400 acatcccttc ttttgaatgg cctctttgtg accagccaga cctcaggtct tcactctttc 2460 ttctttgtaa accatgtcat gtggaaagat ttcctcagtt agtgagcttg tgtctgcaaa 2520 ttgattttgt ttgtaatgta ttttgatagc aaatcatgct gcatctatat ctttttcttg 2580 tttgagctgt tactacattg tacatggcat gtgggatcaa ttaaaaattt gttttaaaaa 2640 t 2641 <210> 71 <211> 792 <212> DNA <213> HUMAN <400> 71 atggatgatc gagaggatct ggtgtaccag gcgaagctgg ccgagcaggc tgagcgatac 60 gacgaaatgg tggagtcaat gaagaaagta gcagggatgg atgtggagct gacagttgaa 120 gaaagaaacc tcctatctgt tgcatataag aatgtgattg gagctagaag agcctcctgg 180 agaataatca gcagcattga acagaaagaa gaaaacaagg gaggagaaga caagctaaaa 240 atgattcggg aatatcggca aatggttgag actgagctaa agttaatctg ttgtgacatt 300 ctggatgtac tggacaaaca cctcattcca gcagctaaca ctggcgagtc caaggttttc 360 tattataaaa tgaaagggga ctaccacagg tatctggcag aatttgccac aggaaacgac 420 aggaaggagg ctgcggagaa cagcctagtg gcttataaag ctgctagtga tattgcaatg 480 acagaacttc caccaacgca tcctattcgc ttaggtcttg ctctcaattt ttccgtattc 540 tactacgaaa ttcttaattc ccctgaccgt gcctgcaggt tggcaaaagc agcttttgat 600 gatgcaattg cagaactgga tacgctgagt gaagaaagct ataaggactc tacacttatc 660 atgcagttgt tacgtgataa tctgacacta tggacttcag acatgcaggg tgacggtgaa 720 gagcagaata aagaagcgct gcaggacgtg gaagacgaaa atcagtgaga cataagccaa 780 caagagaaac ca 792 <210> 72 <211> 991 <212> DNA <213> HUMAN <400> 72 atgactaagt tttcttcctt ttctctgttt ttcctaatag ttggggctta tatgactcat 60 gtgtgtttca atatggaaat tattggaggg aaagaagtgt cacctcattc caggccattt 120 atggcctcca tccagtatgg cggacatcac gtttgtggag gtgttctgat tgatccacag 180 tgggtgctga cagcagccca ctgccaatat cggtttacca aaggccagtc tcccactgtg 240 gttttaggcg cacactctct ctcaaagaat gaggcctcca aacaaacact ggagatcaaa 300 aaatttatac cattctcaag agttacatca gatcctcaat caaatgatat catgctggtt 360 aagcttcaaa cagccgcaaa actcaataaa catgtcaaga tgctccacat aagatccaaa 420 acctctctta gatctggaac caaatgcaag gttactggct ggggagccac cgatccagat 480 tcattaagac cttctgacac cctgcgagaa gtcactgtta ctgtcctaag tcgaaaactt 540 tgcaacagcc aaagttacta caacggcgac ccttttatca ccaaagacat ggtctgtgca 600 ggagatgcca aaggccagaa ggattcctgt aagggtgact cagggggccc cttgatctgt 660 aaaggtgtct tccacgctat agtctctgga ggtcatgaat gtggtgttgc cacaaagcct 720 ggaatctaca ccctgttaac caagaaatac cagacttgga tcaaaagcaa ccttgtcccg 780 cctcatacaa attaagttac aaataatttt attggatgca cttgcttctt ttttcctaat 840 atgctcgcag gttagagttg ggtgtaagta aagcagagca catatggggt ccatttttgc 900 acttgtaagt cattttatta aggaatcaag ttctttttca cttgtatcac tgatgtattt 960 ctaccatgct ggttttattc taaataaaat t 991 <210> 73 <211> 1883 <212> DNA <213> HUMAN <400> 73 atgcccgaga atgtggcacc ccggagcggg gcgactgccg gggctgccgg cggccgcggg 60 aaaggcgcct atcaggaccg cgacaagcca gcccagatcc gcttcagcaa catttccgcc 120 gccaaagcgg ttgctgatgc tattagaaca agccttggac caaaaggaat ggataaaatg 180 attcaagatg gaaaaggtga tgtaaccatt acaaatgatg gtgctaccat tctgaaacaa 240 atgcaagtat tacatccagc agccagaatg ctggtggagc tgtctaaggc tcaagatata 300 gaagcaggag atggcaccac atcagtagtc atcattgctg gctccctctt agattcttgt 360 accaagcttc ttcagaaagg gattcatcca accatcattt ctgagtcatt ccagaaggcc 420 ctggaaaagg gcattgaaat cttgactgac atgtctcgac ctgtggaact gagtgacaga 480 gaaactttgt taaatagtgc aaccacttca ctgaactcaa aggtggtttc tcagtattca 540 agtctgcttt ctccaatgag tgtaaatgca gtgatgaaag tgattgaccc agccacagcc 600 accagtgtag atcttagaga tattaaaata gttaagaagc ttggtgggac aattgatgac 660 tgtgagttgg tggaagggct ggttctcacc caaaaagtgt caaattctgg cataaccaga 720 gttgaaaagg ccaagattgg gcttattcag ttttgcttat ctgctcccaa aacagacatg 780 gataatcaaa tagtggtttc tgactatgcc cagatggacc gagtgctgcg agaagagaga 840 gcctatattt taaatttagt gaagcaaatt aaaaaaacag gatgtaatgt ccttctcata 900 cagaaatcta ttctaagaga tgctcttagt gatcttgcat tacactttct gaataaaatg 960 aagatcatgg tgattaagga tattgaaaga gaagacattg aattcatttg taagacaatt 1020 ggaaccaagc cagttgctca tattgaccaa tttactgctg acatgctggg ttctgctgag 1080 ttagctgagg aggtcaattt aaatggttct ggcaaactgc tcaagattac aggctgtgcc 1140 agccctggaa aaacagttac aattgttgtt cgtggttcta acaaactggt gattgaagaa 1200 gctgagcgct ccattcatga tgccctatgt gttattcgtt gtttagtgaa gaagagggct 1260 cttattgcag gaggtggtgc tccagaaata gagttggccc tagcattaac tgaatattca 1320 cgaacactga gtggtatgga atcctactgc gttcgtgctt ttgcagatgc tatggaggtc 1380 attccatcta cactagctga aaatgccggc ctgaatccca tttctacagt aacagaacta 1440 agaaaccggc atgcccaggg agaaaaaact gcaggcatta atgtccgaaa gggtggtatt 1500 tccaacattt tggaggaact ggttgtccag cctctgttgg tatcagtcag tgctctgact 1560 cttgcaactg aaactgttcg gagcattctg aaaatagatg atgtggtaaa cactcgataa 1620 tctggataac tgactagcac cattatgatc accagtattg tggctggaat ggaagaagat 1680 caccttggtg ttccttgttt ggaagattat ttcctctgaa tttctgggct tggtcttcca 1740 gttggcattt gcctgaagtt gtattgaaac aatttaatga aaatattaaa tatttggttt 1800 caaaaggcag atttatcttc tcccaacatt ctgttatttc tgatactttt gaaaaactaa 1860 taaaaactaa taaaagaagc gta 1883 <210> 74 <211> 2025 <212> DNA <213> HUMAN <400> 74 ggcagcggtg gcaggggctg caggagcaag tgaccaggag caggactggg gacaggcctg 60 atcgcccctg cacgaaccag acccttcgcc gccctcacga tgactacctc tccgatcctg 120 cagctgctgc tgcggctctc actgtgcggg ctgctgctcc agagggcgga gacaggctct 180 aaggggcaga cggcggggga gctgtaccag cgctgggaac ggtaccgcag ggagtgccag 240 gagaccttgg cagccgcgga accgccttca ggcctcgcct gtaacgggtc cttcgatatg 300 tacgtctgct gggactatgc tgcacccaat gccactgccc gtgcgtcctg cccctggtac 360 ctgccctggc accaccatgt ggctgcaggt ttcgtcctcc gccagtgtgg cagtgatggc 420 caatggggac tttggagaga ccatacacaa tgtgagaacc cagagaagaa tgaggccttt 480 ctggaccaaa ggctcatctt ggagcggttg caggtcatgt acactgtcgg ctactccctg 540 tctctcgcca cactgctgct agccctgctc atcttgagtt tgttcaggcg gctacattgc 600 actagaaact atatccacat caacctgttc acgtctttca tgctgcgagc tgcggccatt 660 ctcagccgag accgtctgct acctcgacct ggcccctacc ttggggacca ggcccttgcg 720 ctgtggaacc aggccctcgc tgcctgccgc acggcccaga tcgtgaccca gtactgcgtg 780 ggtgccaact acacgtggct gctggtggag ggcgtctacc tgcacagtct cctggtgctc 840 gtgggaggct ccgaggaggg ccacttccgc tactacctgc tcctcggctg gggggccccc 900 gcgcttttcg tcattccctg ggtgatcgtc aggtacctgt acgagaacac gcagtgctgg 960 gagcgcaacg aagtcaaggc catttggtgg attatacgga cccccatcct catgaccatc 1020 ttgattaatt tcctcatttt tatccgcatt cttggcattc tcctgtccaa gctgaggaca 1080 cggcaaatgc gctgccggga ttaccggctg aggctggctc gctccacgct gacgctggtg 1140 cccctgctgg gtgtccacga ggtggtgttt gctcccgtga cagaggaaca ggcccggggc 1200 gccctgcgct tcgccaagct cggctttgag atcttcctca gctccttcca gggcttcctg 1260 gtcagcgtcc tctactgctt catcaacaag gaggtgcagt cggagatccg ccgtggctgg 1320 caccactgcc gcctgcgccg cagcctgggc gaggagcaac gccagctccc ggagcgcgcc 1380 ttccgggccc tgccctccgg ctccggcccg ggcgaggtcc ccaccagccg cggcttgtcc 1440 tcggggaccc tcccagggcc tgggaatgag gccagccggg agttggaaag ttactgctag 1500 ggggcgggat ccccgtgtct gttcagttag catggattta ttgagtgcca actgcgtgcc 1560 aggcccagta cggaggacgc tggggaaatg gtgaaggaaa cagaaaaaag gtccctgccc 1620 ttctggagat gacaactgag tggggaaaac agaccgtgaa cacaaaacat caagttccac 1680 acacgctatg gaatggttat gaagggaagc gagaaggggg cctagggtgg tctgggaggc 1740 gtctccaagg aggtgacact taagccatcc ccgaaagagg tgaaagagat cactttgggg 1800 agagctggag aacaggattc taggcggaag cgatagcata ggcaaaggcc cttgggcagg 1860 aaggcgctca gccttggctg gagtagaatt aagtcagagc caacaggttg gggagagaca 1920 gagaagtggg caggggcacc caagttggga tttcatttca ggtgcattgg agattcttag 1980 gagtgtctct tgggggtaat attttatttt ttaaaaaatg aggat 2025 <210> 75 <211> 1610 <212> DNA <213> HUMAN <400> 75 ggcggtgctc tacgtcttca ccgctggaga tctgctgccc cgggcaggtc cccgtttcct 60 cacgcggctc ttcgaaggct ctggggaggc ccgagggggc ggccgctcta gggaagggac 120 catggagctc cgaactaccc ctcagctgaa agtggtgggg cagggccgcg gcaatggaga 180 cccggggggt gggatggaga aggacggtcc ggaatgggac ctttgacagc agaccctaca 240 acctgctgcc cttccctgtc cctttccacc ccccacccac cctccagagg tcctcccgac 300 ggccatgaac actacatctt ctgcagcacc cccctcacta ggtgtagagt tcatctctct 360 gctggctatc atcctgctgt cagtggcgct ggctgtgggg cttcccggca acagctttgt 420 ggtgtggagt atcctgaaaa ggatgcagaa gcgctctgtc actgccctga tggtgctgaa 480 cctggccctg gccgacctgg ccgtattgct cactgctccc tttttccttc acttcctggc 540 ccaaggcacc tggagttttg gactggctgg ttgccgcctg tgtcactatg tctgcggagt 600 cagcatgtac gccagcgtcc tgcttatcac ggccatgagt ctagaccgct cactggcggt 660 ggcccgcccc tttgtgtccc agaagctacg caccaaggcg atggcccggc gggtgctggc 720 aggcatctgg gtgttgtcct ttctgctggc cacacccgtc ctcgcgtacc gcacagtagt 780 gccctggaaa acgaacatga gcctgtgctt cccgcggtac cccagcgaag ggcaccgggc 840 cttccatcta atcttcgagg ctgtcacggg cttcctgctg cccttcctgg ctgtggtggc 900 cagctactcg gacatagggc gtcggctaca ggcccggcgc ttccgccgca gccgccgcac 960 cggccgcctg gtggtgctca tcatcctgac cttcgccgcc ttctggctgc cctaccacgt 1020 ggtgaacctg gctgaggcgg gccgcgcgct ggccggccag gccgccgggt tagggctcgt 1080 ggggaagcgg ctgagcctgg cccgcaacgt gctcatcgta ctcgccttcc tgagcagcag 1140 cgtgaacccc gtgctgtacg cgtgcgccgg cggcggcctc gtgcgctcgg cgggcgtggg 1200 cttcgtcgcc aagctgctgg agggcacggg ctccgaggcg tccagcacgc gccgcggggg 1260 cagcctgggc cagaccgcta ggagcggccc cgccgctctg gagcccggcc cttccgagag 1320 cctcactgcc tccagccctc tcaagttaaa cgaactgaac taggcctggt ggaaggaggc 1380 gcactttcct cctggcagaa tgctagctct gagccagttc agtacctgga ggaggagcag 1440 gggcgtggag ggcgtggagg gcgtgggagc gtgggaggcg ggagtggagt ggaagaagag 1500 ggagagatgg agcaaagtga gggccgagtg agagcgtgct ccagcctggc tcccacaggc 1560 agctttaacc attaaaactg aagtctgaaa tttggtcaaa aaaaaaaaaa 1610 <210> 76 <211> 2834 <212> DNA <213> HUMAN <400> 76 gcccactccc accgccagct ggaaccctgg ggactacgac gtccctcaaa ccttgcttct 60 aggagataaa aagaacatcc agtcatggat aaaaatgagc tggttcagaa ggccaaactg 120 gccgagcagg ctgagcgata tgatgacatg gcagcctgca tgaagtctgt aactgagcaa 180 ggagctgaat tatccaatga ggagaggaat cttctctcag ttgcttataa aaatgttgta 240 ggagcccgta ggtcatcttg gagggtcgtc tcaagtattg aacaaaagac ggaaggtgct 300 gagaaaaaac agcagatggc tcgagaatac agagagaaaa ttgagacgga gctaagagat 360 atctgcaatg atgtactgtc tcttttggaa aagttcttga tccccaatgc ttcacaagca 420 gagagcaaag tcttctattt gaaaatgaaa ggagattact accgttactt ggctgaggtt 480 gccgctggtg atgacaagaa agggattgtc gatcagtcac aacaagcata ccaagaagct 540 tttgaaatca gcaaaaagga aatgcaacca acacatccta tcagactggg tctggccctt 600 aacttctctg tgttctatta tgagattctg aactccccag agaaagcctg ctctcttgca 660 aagacagctt ttgatgaagc cattgctgaa cttgatacat taagtgaaga gtcatacaaa 720 gacagcacgc taataatgca attactgaga gacaacttga cattgtggac atcggatacc 780 caaggagacg aagctgaagc aggagaagga ggggaaaatt aaccggcctt ccaacttttg 840 tctgcctcat tctaaaattt acacagtaga ccatttgtca tccatgctgt cccacaaata 900 gttttttgtt tacgatttat gacaggttta tgttacttct atttgaattt ctatatttcc 960 catgtggttt ttatgtttaa tattagggga gtagagccag ttaacattta gggagttatc 1020 tgttttcatc ttgaggtggc caatatgggg atgtggaatt tttatacaag ttataagtgt 1080 ttggcatagt acttttggta cattgtggct tcaaaagggc cagtgtaaaa ctgcttccat 1140 gtctaagcaa agaaaactgc ctacatactg gtttgtcctg gcggggaata aaagggatca 1200 ttggttccag tcacaggtgt agtaattgtg ggtactttaa ggtttggagc acttacaagg 1260 ctgtggtaga atcatacccc atggatacca catattaaac catgtatatc tgtggaatac 1320 tcaatgtgta cacctttgac tacagctgca gaagtgttcc tttagacaaa gttgtgaccc 1380 attttactct ggataagggc agaaacggtt cacattccat tatttgtaaa gttacctgct 1440 gttagctttc attatttttg ctacactcat tttatttgta tttaaatgtt ttaggcaacc 1500 taagaacaaa tgtaaaagta aagatgcagg aaaaatgaat tgcttggtat tcattacttc 1560 atgtatatca agcacagcag taaaacaaaa acccatgtat ttaacttttt tttaggattt 1620 ttgcttttgt gatttttttt tttttttttt gatacttgcc taacatgcat gtgctgtaaa 1680 aatagttaac agggaaataa cttgagatga tggctagctt tgtttaatgt cttatgaaat 1740 tttcatgaac aatccaagca taattgttaa gaacacgtgt attaaattca tgtaagtgga 1800 ataaaagttt tatgaatgga cttttcaact actttctcta cagcttttca tgtaaattag 1860 tcttggttct gaaacttctc taaaggaaat tgtacattct ttgaaattta ttccttattc 1920 cctcttggca gctaatgggc tcttaccaag tttaaacaca aaatttatca taacaaaaat 1980 actactaata taactactgt ttccatgtcc catgatcccc tctcttcctc cccaccctga 2040 aaaaaatgag ttcctatttt ttctgggaga gggggggatt gattagaaaa aaatgtagtg 2100 tgttccattt aaaattttgg catatggcat tttctaactt aggaagccac aatgttcttg 2160 gcccatcatg acattgggta gcattaactg taagttttgt gcttccaaat cactttttgg 2220 tttttaagaa tttcttgata ctcttatagc ctgccttcaa ttttgatcct ttattctttc 2280 tatttgtcag gtgcacaaga ttaccttcct gttttagcct tctgtcttgt caccaaccat 2340 tcttacttgg tggccatgta cttggaaaaa ggccgcatga tctttctggc tccactcagt 2400 gtctaaggca ccctgcttcc tttgcttgca tcccacagac tatttccctc atcctattta 2460 ctgcagcaaa tctctcctta gttgatgaga ctgtgtttat ctccctttaa aaccctacct 2520 atcctgaatg gtctgtcatt gtctgccttt aaaatccttc ctctttcttc ctcctctatt 2580 ctctaaataa tgatggggct aagttatacc caaagctcac tttacaaaat atttcctcag 2640 tactttgcag aaaacaccaa acaaaaatgc cattttaaaa aaggtgtatt ttttctttta 2700 gaatgtaagc tcctcaagag cagggacaat gttttctgta tgttctattg tgcctagtac 2760 actgtaaatg ctcaataaat attgatgatg ggaggcagtg agtcttgatg ataagggtga 2820 gaaactgaaa tccc 2834 <210> 77 <211> 5389 <212> DNA <213> HUMAN <400> 77 gcggccgcgc aagtcctcca ccatgtgaat gccaacatgg ccaggtcatt agagctgagg 60 gaaaactagt gcccaaagat atgaaaagag tgtggatctt ctggagaagt gctgttgttc 120 aacaggtaca aaattggaaa tgttggcttc accagaacct aagggccttg ttcccttcac 180 taaagagtct tttgaactta taaaacagca tattgctaaa acacataatg aagaccatga 240 agaagaagac ttaaagccaa atcctgattt ggaagttggc aaaaagcttc catttattta 300 tggaaacctt tctcaaggaa tggtgtcaga gcccttggaa gatgtggacc catattacta 360 caagaaaaaa aatactttca tagtattaaa taaaaataga acaatcttca gattcaatgc 420 ggcttccatc ttgtgtacat tgtctccttt caattgtatt agaagaacaa ctatcaaggt 480 tttggtacat ccctttttcc aactgtttat tctaattagt gtcctgattg attgcgtatt 540 catgtccctg actaatttgc caaaatggag accagtatta gagaatactt tgcttggaat 600 ttacacattt gaaatacttg taaaactctt tgcaagaggt gtctgggcag gatcattttc 660 cttcctcggt gatccatgga actggctcga tttcagcgta actgtgtttg aggttattat 720 aagatactca cctctggact tcattccaac gcttcaaact gcaagaactt tgagaatttt 780 aaaaattatt cctttaaatc aaggtctgaa atcccttgta ggggtcctga tccactgctt 840 gaagcagctt attggtgtca ttatcctaac tctgtttttt ctgagcatat tttctctaat 900 tgggatgggg ctcttcatgg gcaacttgaa acacaaatgt tttcgatggc cccaagagaa 960 tgaaaatgaa accctgcaca acagaactgg aaacccatat tatattcgag aaacagaaaa 1020 cttttattat ttggaaggag aaagatatgc tctcctttgt ggcaacagga cagatgctgg 1080 tcagtgtcct gaaggatatg tgtgtgtaaa agctggcata aatcctgatc aaggcttcac 1140 aaattttgac agttttggct gggccttatt tgccctattt cggttaatgg ctcaggatta 1200 ccctgaagta ctttatcacc tgatacttta tgcttctggg aaggtctaca tgatattttt 1260 tgtggtggta agttttttgt tttcctttta tatggcaagt ttgttcttag gcatacttgc 1320 catggcctat gaagaagaaa agcagagagt tggtgaaata tctaagaaga ttgaaccaaa 1380 atttcaacag actggaaaag aacttcaaga aggaaatgaa acagatgagg ccaagaccat 1440 acaaatagaa atgaagaaaa ggtcaccaat ttccacagac acatcattgg atgtgttgga 1500 agatgctact ctcagacata aggaagaact tgaaaaatcc aagaagatat gcccattata 1560 ctggtataag tttgctaaaa ctttcttgat ctggaattgt tctccctgtt ggttaaaatt 1620 gaaagagttt gtccatagga ttataatggc accatttact gatcttttcc ttatcatatg 1680 cataatttta aacgtatgtt ttctgacctt ggagcattat ccaatgagta aacaaactaa 1740 cactcttctc aacattggaa acctggtttt cattggaatt ttcacagcag aaatgatttt 1800 taaaataatt gcaatgcatc catatgggta tttccaagta ggttggaaca tttttgatag 1860 catgatagtg ttccatggtt taatagaact ttgtctagca aatgttgcag gaatggctct 1920 tcttcgatta ttcaggatgt taagaatttt caagttggga aagtattggc caacattcca 1980 gattttgatg tggtctctta gtaactcatg ggtggccctg aaagacttgg tcctgttgtt 2040 gttcacattc atcttctttt ctgctgcatt cggcatgaag ctgtttggta agaattatga 2100 agaatttgtc tgccacatag acaaagactg tcaactccca cgctggcaca tgcatgactt 2160 tttccactcc ttcctgaatg tgttccgaat tctctgtgga gagtgggtag agaccttgtg 2220 ggactgtatg gaggttgcag gccaatcctg gtgtattcct ttttacctga tggtcatttt 2280 aattggaaat ttactggtac tttacctgtt tctggcattg gtgagctcat ttagttcatg 2340 caaggatgta acagctgaag agaataatga agcaaaaaat ctccagcttg cagtggcaag 2400 aattaaaaaa ggaataaact atgtgcttct taaaatacta tgcaaaacac aaaatgtccc 2460 aaaggacaca atggaccatg taaatgaggt atatgttaaa gaagatattt ctgaccatac 2520 cctttctgaa ttgagcaaca cccaagattt tctcaaagat aaggaaaaaa gcagtggcac 2580 agagaaaaac gctactgaaa atgagagcca atcacttatc cccagtccta gtgtctcaga 2640 aactgtacca attgcttcag gagaatctga tatagaaaat ctggataata aggagattca 2700 gagtaagtct ggtgatggag gcagcaaaga gaaaataaag caatctagct catctgaatg 2760 cagtactgtt gatattgcta tctctgaaga agaagaaatg ttctatggag gtgaaagatc 2820 aaagcatctg aaaaatggtt gcagacgcgg atcttcactt ggtcaaatca gtggagcatc 2880 caagaaagga aaaatctggc agaacatcag gaaaacctgc tgcaagattg tagagaacaa 2940 ttggtttaag tgttttattg ggcttgttac tctgctcagc actggcactc tggcttttga 3000 agatatatat attgatcaga gaaagacaat taaaatttta ttagaatatg ctgacatgat 3060 ctttacttat atcttcattc tggaaatgct tctaaaatgg atggcatatg gttttaaggc 3120 ctatttctct aatggctggt acaggctgga cttcgtggtt gttattgtgt tttgtcttag 3180 cttaataggc aaaactcggg aagaactaaa acctcttatt tccatgaaat tccttcggcc 3240 cctcagagtt ctatctcaat ttgaaagaat gaaggtggtt gtgagagctt tgatcaaaac 3300 aaccttaccc actttgaatg tgtttcttgt ctgcctgatg atctggctga tttttagtat 3360 catgggagta gacttatttg ctggcagatt ctatgaatgc attgacccaa caagtggaga 3420 aaggtttcct tcatctgaag tcatgaataa gagtcggtgt gaaagccttc tgtttaacga 3480 atccatgcta tgggaaaatg caaaaatgaa ctttgataat gttggaaatg gtttcctttc 3540 tctgcttcaa gtagcaacat ttaatggatg gatcactatt atgaattcag caattgattc 3600 tgttgctgtt aatatacagc ctcattttga agtcaacatc tacatgtatt gttactttat 3660 caactttatt atatttggag tatttctccc tctgagtatg ctgattactg ttattattga 3720 taatttcaac aagcataaaa taaagctggg aggctcaaat atctttataa cggttaaaca 3780 gagaaaacag taccgcaggc tgaagaagct aatgtatgag gattctcaaa gaccagtacc 3840 tcgcccatta aacaagctcc aaggattcat ctttgatgtg gtaacaagcc aagcttttaa 3900 tgtcattgtt atggttctta tatgtttcca agcaatagcc atgatgatag acactgatgt 3960 tcagagtcta caaatgtcca ttgctctcta ctggattaac tcaatttttg ttatgctata 4020 tactatggaa tgtatactga agctcatcgc tttccgttgt ttttatttca ccattgcgtg 4080 gaacattttt gattttatgg tggttatttt ctccatcaca ggactatgtc tgcctatgac 4140 agtaggatcc taccttgtgc ctccttcact tgtgcaactg atacttctct cacggatcat 4200 tcacatgctg cgtcttggaa aaggaccaaa ggtgtttcat aatctgatgc ttcctttgat 4260 gctgtccctc ccagcattat tgaacatcat tcttctcatc ttcctggtca tgttcatcta 4320 tgccgtattt ggaatgtata attttgccta tgttaaaaaa gaagctggaa ttaatgatgt 4380 gtctaatttt gaaacctttg gcaacagtat gctctgtctt tttcaagttg caatatttgc 4440 tggttgggat gggatgcttg atgcaatttt caacagtaaa tggtctgact gtgatcctga 4500 taaaattaac cctgggactc aagttagagg agattgtggg aacccctctg ttgggatttt 4560 ttattttgtc agttatatcc tcatatcatg gctgatcatt gtaaatatgt acattgttgt 4620 tgtcatggag tttttaaata ttgcttctaa gaagaaaaac aagaccttga gtgaagatga 4680 ttttaggaaa ttctttcagg tatggaaaag gtttgatcct gataggaccc agtacataga 4740 ctctagcaag ctttcagatt ttgcagctgc tcttgatcct cctcttttca tggcaaaacc 4800 aaacaagggc cagctcattg ctttggacct ccccatggct gttggggaca gaattcattg 4860 cctcgatatc ttacttgctt ttacaaagag agttatgggt caagatgtga ggatggagaa 4920 agttgtttca gaaatagaat cagggttttt gttagccaac ccttttaaga tcacatgtga 4980 gccaattacg actactttga aacgaaaaca agaggcagtt tcagcaacca tcattcaacg 5040 tgcttataaa aattaccgct tgaggcgaaa tgacaaaaat acatcagata ttcatatgat 5100 agatggtgac agagatgttc atgctactaa agaaggtgcc tattttgaca aagctaagga 5160 aaagtcacct attcaaagcc agatctaata ccacttacca cctcttttca tatttcttca 5220 catatctgaa aaatgttgaa agcctaagcc aggaataaaa gaaaagtaga gataataatc 5280 agttctttac aaccgatggt aattaagctt gtattcacaa gacttcatgc caaattcact 5340 ttttagcatt atatctaaca aatcaagaga atccttaata ttgctgcag 5389 <210> 78 <211> 1255 <212> DNA <213> HUMAN <400> 78 ctaaagatga aacggctggt ttgtgtgctc ttggtgtgct cctctgcagt ggcacagttg 60 cataaagatc ctaccctgga tcaccactgg catctctgga agaaaaccta tggcaaacaa 120 tacaaggaaa agaatgaaga agcagtacga cgtctcatct gggaaaagaa tctaaagttt 180 gtgatgcttc acaacctgga gcattcaatg ggaatgcact catacgatct gggcatgaac 240 cacctgggag acatgaccag tgaagaagtg atgtctttga cgagttccct gagagttccc 300 agccagtggc agagaaatat cacatataag tcaaacccta atcggatatt gcctgattct 360 gtggactgga gagagaaagg gtgtgttact gaagtgaaat atcaaggttc ttgtggtgct 420 tgctgggctt tcagtgctgt gggggccctg gaagcacagc tgaagctgaa aacaggaaag 480 ctggtgactc tcagtgccca gaacctggtg gattgctcaa ctgaaaaata tggaaacaaa 540 ggctgcaatg gtggcttcat gacaacggct ttccagtaca tcattgataa caagggcatc 600 gactcagacg cttcctatcc ctacaaagcc atggatcaga aatgtcaata tgactcaaaa 660 tatcgtgctg ccacatgttc aaagtacact gaacttcctt atgggagaga agatgtcctg 720 aaagaagctg tggccaataa aggcccagtg tctgttggtg tagatgcgcg tcatccttct 780 ttcttcctct acagaagtgg tgtctactat gaaccatcct gtactcagaa tgtgaatcat 840 ggtgtacttg tggttggcta tggtgatctt aatgggaaag aatactggct tgtgaaaaac 900 agctggggcc acaactttgg tgaagaagga tatattcgga tggcaagaaa taaaggaaat 960 cattgtggga ttgctagctt tccctcttac ccagaaatct agaggatctc tcctttttat 1020 aacaaatcaa gaaatatgaa gcactttctc ttaacttaat ttttcctgct gtatccagaa 1080 gaaataattg tgtcatgatt aatgtgtatt tactgtacta atagaaaata tagtttgagg 1140 ccgggcactg tctggctcac gcctgtaatc ccagtacttg ggaggccaag gaggcatatc 1200 aacttgaggc caggagttaa agagcagcct ggctaactgt gaaaccctct ctact 1255 <210> 79 <211> 889 <212> DNA <213> HUMAN <400> 79 ctgcgcctct cttccccaga cctgcgcgct actgcggctc gggcggtcgc tcgcctggct 60 ctgctccatt tgactgtctg tgtgcagtcg cagaacttcg aagagggttt tgcgctccat 120 ccgtggcgtt tcgcttttgt tcggttttgt tgtttatttc attttttttt ttccggagag 180 aggcgaggcg gtggtccaca cccgcccgag gaggaagatg tcaaacgtga gagtgtctaa 240 cgggagcccg agcctggagc ggatggacgc cagacaagcg gatcacccca agccttccgc 300 ctgcagaaat ctcttcggcc cggtcaatca tgaagaacta acccgggact tggagaagca 360 ctgccgggat atggaagaag cgagtcagcg caagtggaat ttcgactttc agaatcataa 420 gcccctggag ggcagatacg aatggcagga ggtggagagg ggcagcttgc ccgagttcta 480 ctacaggccc ccgcgccccc ccaagagcgc ctgcaaggtg ctggcgcagg agagccagga 540 tgtcagcggg agccgccagg cggtgccttt aattgggtct caggcaaact ctgaggaccg 600 gcatttggtg gaccaaatgc ctgactcgtc agacaatcag gctgggttag cggagcagtg 660 tccagggatg aggaagcgac ctgctgcaga agattcttct tcgcaaaaca aaagggccaa 720 cagaacagaa gaaaatgttt cagacggttc cccgaacgct ggcactgtgg agcagacgcc 780 caagaagccc ggccttcgac gccagacgta aacagctccg aattaagaat atttccttgt 840 ttattagata catcactgct ttatgaagca aggaagatat acatgaaaa 889 <210> 80 <211> 1182 <212> DNA <213> HUMAN <400> 80 tgcagcactc accatggaat ccccgattca gatcttccgc ggggagcctg gccctacctg 60 cgccccgagc gcctgcctgc cccccaacag cagcgcctgg tttcccggct gggccgagcc 120 cgacagcaac ggcagcgccg gctcggagga cgcgcagctg gagcccgcgc acatctcccc 180 ggccatcccg gtcatcatca cggcggtcta ctccgtagtg ttcgtcgtgg gcttggtggg 240 caactcgctg gtcatgttcg tgatcatccg atacacaaag atgaagacag caaccaacat 300 ttacatattt aacctggctt tggcagatgc tttagttact acaaccatgc cctttcagag 360 tacggtctac ttgatgaatt cctggccttt tggggatgtg ctgtgcaaga tagtaatttc 420 cattgattac tacaacatgt tcaccagcat cttcaccttg accatgatga gcgtggaccg 480 ctacattgcc gtgtgccacc ccgtgaaggc tttggacttc cgcacaccct tgaaggcaaa 540 gatcatcaat atctgcatct ggctgctgtc gtcatctgtt ggcatctctg caatagtcct 600 tggaggcacc aaagtcaggg aagacgtcga tgtcattgag tgctccttgc agttcccaga 660 tgatgactac tcctggtggg acctcttcat gaagatctgc gtcttcatct ttgccttcgt 720 gatccctgtc ctcatcatca tcgtctgcta caccctgatg atcctgcgtc tcaagagcgt 780 ccggctcctt tctggctccc gagagaaaga tcgcaacctg cgtaggatca ccagactggt 840 cctggtggtg gtggcggttt tcgtcgtctg ctggactccc attcacatat tcatcctggt 900 ggaggctctg gggagcacct cccacagcac agctgctctc tccagctatt acttctgcat 960 cgccttaggc tataccaaca gtagcctgaa tcccattctc tacgcctttc ttgatgaaaa 1020 cttcaagcgg tgtttccggg acttctgctt tccactgaag atgaggatgg agcggcagag 1080 cactagcaga gtccgaaata cagttcagga tcctgcttac ctgagggaca tcgatgggat 1140 gaataaacca gtatgactag tcgtggagat gtcttcgtac ag 1182 <210> 81 <211> 1507 <212> DNA <213> HUMAN <400> 81 atggggcgcc cactgcacct cgtcctgctc agtgcctccc tggctggcct cctgctgctc 60 ggggaaagtc tgttcatccg cagggagcag gccaacaaca tcctggcgag ggtcacgagg 120 gccaattcct ttcttgaaga gatgaagaaa ggacacctcg aaagagagtg catggaagag 180 acctgctcat acgaagaggc ccgcgaggtc tttgaggaca gcgacaagac gaatgaattc 240 tggaataaat acaaagatgg cgaccagtgt gagaccagtc cttgccagaa ccagggcaaa 300 tgtaaagacg gcctcgggga atacacctgc acctgtttag aaggattcga aggcaaaaac 360 tgtgaattat tcacacggaa gctctgcagc ctggacaacg gggactgtga ccagttctgc 420 cacgaggaac agaactctgt ggtgtgctcc tgcgcccgcg ggtacaccct ggctgacaac 480 ggcaaggcct gcattcccac agggccctac ccctgtggga aacagaccct ggaacgcagg 540 aagaggtcag tggcccaggc caccagcagc agcggggagg cccctgacag catcacatgg 600 aagccatatg atgcagccga cctggacccc accgagaacc ccttcgacct gcttgacttc 660 aaccagacgc agcctgagag gggcgacaac aacctcacca ggatcgtggg aggccaggaa 720 tgcaaggacg gggagtgtcc ctggcaggcc ctgctcatca atgaggaaaa cgagggtttc 780 tgtggtggaa ctattctgag cgagttctac atcctaacgg cagcccactg tctctaccaa 840 gccaagagat tcaaggtgag ggtaggggac cggaacacgg agcaggagga gggcggtgag 900 gcggtgcacg aggtggaggt ggtcatcaag cacaaccggt tcacaaagga gacctatgac 960 ttcgacatcg ccgtgctccg gctcaagacc cccatcacct tccgcatgaa cgtggcgcct 1020 gcctgcctcc ccgagcgtga ctgggccgag tccacgctga tgacgcagaa gacggggatt 1080 gtgagcggct tcgggcgcac ccacgagaag ggccggcagt ccaccaggct caagatgctg 1140 gaggtgccct acgtggaccg caacagctgc aagctgtcca gcagcttcat catcacccag 1200 aacatgttct gtgccggcta cgacaccaag caggaggatg cctgccaggg ggacagcggg 1260 ggcccgcacg tcacccgctt caaggacacc tacttcgtga caggcatcgt cagctgggga 1320 gagggctgtg cccgtaaggg gaagtacggg atctacacca aggtcaccgc cttcctcaag 1380 tggatcgaca ggtccatgaa aaccaggggc ttgcccaagg ccaagagcca tgccccggag 1440 gtcataacgt cctctccatt aaagtgagat cccactcaaa aaaaaaaaaa aaaaaaaaaa 1500 aaaaaaa 1507 <210> 82 <211> 3330 <212> DNA <213> HUMAN <400> 82 ggatcctatg agcctgggag gtcaggactg cagtgagcca tgattacacc actgcagtgc 60 agcctgcgtg acaaaacgag accctgtctc taaaaaatga gaaaaaaaaa tggttgttac 120 caggcgataa agggagggga aaacgggagt tacttaatga gtatacagtt tcagttttgc 180 gagatgaaca gaattctgga aattggttga acaccgctgt gattgaactc actaccaaac 240 tctacactta aaaatggtta agatggtaca atttgtatgt attttaccac aataaaaaat 300 aaaaaaaagg ctgggcgaga tgttcactcc tgtaatccca gtacttgggg aggctggggc 360 tgaaggatcg tttgagccct gaaggagttt gagaccagcc tgagcaacat aaggagaccc 420 catctgtaca caaaattaaa acattagcca ggcagagagc tggtcacggt ggctcacgta 480 tgtaatccca gcactttggg aggccgaggc gggcgggcgg atcacctgag gtcaggagtt 540 tgagaccagc ctggccaaca tagtgaaacc gtgaaacccc atctctacta aaaatacaaa 600 aattagctgg gcgtggtggt gccctcataa tcccagccac tcgggaggct gagacaggag 660 aatcgcttga actcaggagg tggaggttgc agtgagccta gatcacacca ctgcagtcca 720 aagcaagact ccgtctcaaa aaaaaaaaaa attagcccgg ctgttgtctc cagttattct 780 ggaggctaag gcaggaagat tgctggagcc taggagatca aagctgcagt gagctatgac 840 tgcgcctctg cactccaacc tgggtgacag aggaagaccc tgtctcaaaa aaataaataa 900 cattgaaaag gaactctccc aaaagtatct tattctttct ccataggcct cagagaacca 960 tggctactgc caagggaatc gccataggaa tcgacctggg caccacctac tcctgtgtgg 1020 gggtgttcca gcacggcaag gtggagatca tcgccaacga ccagggcaac cgcaccaccc 1080 ccagctacgt ggccttcaca gacaccgagc ggctcattgg ggatgcggcc aagaaccagg 1140 tagcaatgaa tccccagaac actgtttttg atgctaaacg tctgatcggc aggaaattta 1200 atgatcctgt tgtacaagca gatatgaaac tttggccttt tcaagtgatt aatgaaggag 1260 gcaagcccaa agtccttgtg tcctacaaag gggagaataa agctttctac cctgaggaaa 1320 tctcttcgat ggtattgact aagttgaagg agactgctga ggcctttttg ggccaccctg 1380 tcaccaatgc agtgattacc gtgccagcct atttcaatga ctctcaacgt caggctacta 1440 aggatgcagg tgtgattgct ggacttaatg tgctaagaat catcaatgag cccacggctg 1500 ctgccattgc ctatggttta gataaaggag gtcaaggaga acgacatgtc ctgatttttg 1560 atctgggtgg aggcacattt gatgtgtcaa ttctgaccat agatgatggg atttttgagg 1620 taaaggccac tgctggggac actcacctgg gtggggagga ctttgacaac aggcttgtga 1680 gccacttcgt ggaggagttc aagaggaaac acaaaaagga catcagccag aacaagcgag 1740 ccgtgaggcg gctgcgcacc gcctgcgaga gggccaagag gaccctgtcg tccagcaccc 1800 aggccaacct agaaattgat tcactttatg aaggcattga cttctataca tccatcacca 1860 gagctcgatt tgaagagttg tgtgcagacc tgtttagggg taccctggag cctgtagaaa 1920 aagcgcttcg ggatgccaag atggataagg ctaaaatcca tgacattgtt ttagtagggg 1980 gctccacccg catccccaag gtgcagcggc tgcttcagga ctacttcaat ggacgtgatc 2040 tcaacaagag catcaaccct gatgaggccg tagcatatgg ggctgcggta caagcagcca 2100 tcctgatggg ggacaagtct gagaaggtac aggacctgct gctgctggac gtggctcccc 2160 tgtccctggg tctggagacg gttgggggcg tgatgactgc cctgataaag cgcaactcca 2220 ccatcccacc caagcagaca cagattttca ccacctactc tgacaaccaa cccggggtgc 2280 tgatccaggt gtatgagggc gagagggcca tgacaaagga caacaacctg ctggggcggt 2340 ttgatctgac tggaatccct ccagcaccca ggggagttcc tcagatcgag gtgacgtttg 2400 acattgatgc caatggtatt ctcaatgtca cagccacgga caagagcacc ggcaaggtga 2460 acaagatcac catcaccaat gacaagggcc gcctgagcaa ggaggagatt gagcggatgg 2520 ttctggatgc tgagaaatat aaagctgaag atgaggtcca gagggagaaa attgctgcaa 2580 agaatgcctt agaatcctat gcttttaaca tgaagagtgt tgtgagtgat gaaggtttga 2640 agggcaagat tagtgagtct gataaaaata aaatattgga taaatgcaac gagctccttt 2700 cgtggctgga ggtcaatcaa ctggcagaga aagatgagtt tgatcataag agaaaggaat 2760 tggagcagat gtgtaaccct atcatcacaa aactctacca aggaggatgc actgggcctg 2820 cctgcggaac agggtatgtg cctggaaggc ctgccacagg ccccacaatt gaagaagtag 2880 attaattctt tttagaactg aagcatccta ggatgcctct acatgtattt cattcccctc 2940 atgttgaaac atcattatta ttcttgacca gacctgaatc taagttacca tcccttggaa 3000 attctggaga aggagtctca tgcaccacct atcacactcc ctcacatcct gtttctgact 3060 ttggaatgga ctcaggaaaa ctaggcccct ctttaaccgt gtgatgtatt tgaatgtctg 3120 ttatttccag ccaccctaac attcttcttc ctgtgtggat gcttatttgt caatcagtaa 3180 atttgttcgt aaagaaaatt acttctggta tttaggctgt gaatgtacct tgaaggggag 3240 agttcatgga gagagcatgt gttctctgat tgtgaggtca ctgtgaatga ttaaattggt 3300 aagggtaaag tatttgaatt ttcatgaact 3330 <210> 83 <211> 2060 <212> DNA <213> HUMAN <400> 83 tgttcccagc actcaagcct tgccaccgcc gagccgggct tcctgggtgt ttcaggcaag 60 gaagtctagg tccctggggg gtgaccccca aggaaaaggc agcctccctg cgcacccggt 120 tgcccggagc cctctccagg gccggctggg ctgggggttg ccctggccag caggggcccg 180 ggggcgatgc cacccggtgc cgactgaggc caccgcacca tggcccgctc gctgacctgg 240 cgctgctgcc cctggtgcct gacggaggat gagaaggccg ccgcccgggt ggaccaggag 300 atcaacagga tcctcttgga gcagaagaag caggaccgcg gggagctgaa gctgctgctt 360 ttgggcccag gcgagagcgg gaagagcacc ttcatcaagc agatgcggat catccacggc 420 gccggctact cggaggagga gcgcaagggc ttccggcccc tggtctacca gaacatcttc 480 gtgtccatgc gggccatgat cgaggccatg gagcggctgc agattccatt cagcaggccc 540 gagagcaagc accacgctag cctggtcatg agccaggacc cctataaagt gaccacgttt 600 gagaagcgct acgctgcggc catgcagtgg ctgtggaggg atgccggcat ccgggcctgc 660 tatgagcgtc ggcgggaatt ccacctgctc gattcagccg tgtactacct gtcccacctg 720 gagcgcatca ccgaggaggg ctacgtcccc acagctcagg acgtgctccg cagccgcatg 780 cccaccactg gcatcaacga gtactgcttc tccgtgcaga aaaccaacct gcggatcgtg 840 gacgtcgggg gccagaagtc agagcgtaag aaatggatcc attgtttcga gaacgtgatc 900 gccctcatct acctggcctc actgagtgaa tacgaccagt gcctggagga gaacaaccag 960 gagaaccgca tgaaggagag cctcgcattg tttgggacta tcctggaact accctggttc 1020 aaaagcacat ccgtcatcct ctttctcaac aaaaccgaca tcctggagga gaaaatcccc 1080 acctcccacc tggctaccta tttccccagt ttccagggcc ctaagcagga tgctgaggca 1140 gccaagaggt tcatcctgga catgtacacg aggatgtaca ccgggtgcgt ggacggcccc 1200 gagggcagca agaagggcgc acgatcccga cgccttttca gccactacac atgtgccaca 1260 gacacacaga acatccgcaa ggtcttcaag gacgtgcggg actcggtgct cgcccgctac 1320 ctggacgaga tcaacctgct gtgacccagg ccccacctgg ggcaggcggc accggcgggc 1380 gggtgggagg tgggagtggc tgcagggacc ctagtgtcct ggtctatctc tccagcctcg 1440 gcccacacgc aagggagtcg ggggacggcc cgctgctggc cgctctcttc tctgcctctc 1500 accaggacag ccgcccccca gggtactcct gcccttgctt gactcagttt ccctcctttg 1560 aaagggaagg agcaaaacgg ccatttggga tgccagggtg gatgaaaagg tgaagaaatc 1620 aggggattga gacttgggtg ggtgggcatc tctcaggagc cccatctccg ggcgtgtcac 1680 ctcctgggca gggttctggg accctctgtg ggtgacgcac accctgggat ggggctagta 1740 gagccttcag gcgccttcgg gcgtggactc tggcgcactc tagtggacag gagaaggaac 1800 gccttccagg aacctgtgga ctaggggtgc agggacttcc ctttgcaagg ggtaacagac 1860 cgctggaaaa cactgtcact ttcagagctc ggtggctcac agcgtgtcct gccccggttt 1920 gcggacgaga gaaatcgcgg cccacaagca tcccccatcc cttgcaggct gggggctggg 1980 catgctgcat cttaaccttt tgtatttatt ccctcacctt ctgcagggct ccgtgcgggc 2040 tgaaattaaa gatttcttag 2060 <210> 84 <211> 550 <212> DNA <213> HUMAN <400> 84 ggccggggtt gactccgggg gcgcggcgag gagagacatg aggctgagct ggttccgggt 60 cctgacagta ctgtccatct gcctgagcgc cgtggccagc acggggaccg agggcaaaag 120 gaagctgcag atcggggtca agaagcgggt ggaccactgt cccatcaaat cgcgcaaagg 180 ggatgtcctg cacatgcact acacggggaa gctggaagat gggacagagt ttgacagcag 240 cctgccccag aaccagccct ttgtcttctc ccttggcaca ggccaggtca tcaagggctg 300 ggaccagggg ctgctgggga tgtatgaggg ggaaaagcgc aagctggtga tcccatccga 360 gctagggtat ggagagcggg gagctccccc aaagattcca ggcggtgcaa ccctggtgtt 420 cgaggtggag ctgctcaaaa tagagcgacg aactgagctg taaccagact gggaggggca 480 ggggagaggc ccccatcagg accagactgt tccaaaaaaa aaaaaacaaa aaacaaacaa 540 aaaaacactt 550 <210> 85 <211> 1264 <212> DNA <213> HUMAN <400> 85 tggtttgtgg tttttatgaa gagatgtgaa aaaggaagtg tggaatgatg ggatgagaag 60 ttgtatgggg aagatgaata gaagaattag gtggttgaat aaaattaaaa ggtgtgtggt 120 tggatgaatg aatgagtggg atgatagatg gacctaagtg gttagtggat ggacaggagg 180 atggatggat gtgagagccc cagaaggaca taaggaaaga tgggtggata gatggatggg 240 cggatggaag gatatttagg aggatgaatg agcatgtgtg tggagagagg tgcccattca 300 cactggcttg aacacatggg ttagctgagc caaatgccag ccctatgaca ggccatcagt 360 agctttccct gagctgttct gccaagaagc taaaattcat tcaagccatg tggacttgtt 420 attgagggga aaaagaatga gctctccctc tttccacttg gaagattcac caactcccca 480 cccctcactc cccactgtgg gcacggaggc actgcgccac ccagggcaag acctcgccct 540 ctctccagct cctctcccag gatatccaac atccctgtga aaccagagat cttgctccag 600 ccggattcag agaaatttag cgggaaagga gaggccaaag gctgaaccca atggtgcaag 660 gttttacggt tcggtcatcc tctgtcctga cgccgcgggg ccagcgggag aagaaagcca 720 gtgcgtctct gggcgcaggg gccagtgggg ctcggaggca caggcacccc gcgacactcc 780 aggttccccg acccacgtcc ctggcagccc cgattattta cagcctcagc agagcacggg 840 gcgggggcag aggggcccgc ccgggagggc tgctacttct taaaacctct gcgggctgct 900 tagtcacagc cccccttgct tgggtgtgtc cttcgctcgc tccctccctc cgtcttaggt 960 cactgttttc aacctcgaat aaaaactgca gccaacttcc gaggcagcct cattgcccag 1020 cggaccccag cctctgccag gttcggtccg ccatcctcgt cccgtcctcc gccggcccct 1080 gccccgcgcc cagggatcct ccagctcctt tcgcccgcgc cctccgttcg ctccggacac 1140 catggacaag ttttggtggc acgcagcctg gggactctgc ctcgtgccgc tgagcctggc 1200 gcagatcggt gagtgcccgc cgcaggctgg gcagcaagat gggtgcgggg tgctcagcgc 1260 ggac 1264 <210> 86 <211> 865 <212> DNA <213> HUMAN <400> 86 gaattccgga gttccgggcg cgcgcgacgt cagtttgagt tctgtgttct ccccgcccgt 60 gtcccgcccg acccgcgccc gcgatgctgg cgctgcgctg cggctcccgc tggctcggcc 120 tgctctccgt cccgcgctcc gtgccgctgc gcctccccgc ggcccgcgcc tgcagcaagg 180 gctccggcga cccgtcctct tcctcctcct ccgggaaccc gctcgtgtac ctggacgtgg 240 acgccaacgg gaagccgctc ggccgcgtgg tgctggagct gaaggcagat gtcgtcccaa 300 agacagctga gaacttcaga gccctgtgca ctggtgagaa gggcttcggc tacaaaggct 360 ccaccttcca cagggtgatc ccttccttca tgtgccaggc gggcgacttc accaaccaca 420 atggcacagg cgggaagtcc atctacggaa gccgctttcc tgacgagaac tttacactga 480 agcacgtggg gccaggtgtc ctgtccatgg ctaatgctgg tcctaacacc aacggctccc 540 agttcttcat ctgcaccata aagacagact ggttggatgg caagcatgtt gtgttcggtc 600 acgtcaaaga gggcatggac gtcgtgaaga aaatagaatc tttcggctct aagagtggga 660 ggacatccaa gaagattgtc atcacagact gtggccagtt gagctaatct gtggccaggg 720 tgctggcatg gtggcagctg caaatgtcca tgcacccagg tggccgcgtt gggctgtcag 780 ccaaggtgcc tgaaacgata cgtgtgccca ctccactgtc acagtgtgcc tgaggaaggc 840 tgctagggat gttagacgga attcc 865 <210> 87 <211> 1551 <212> DNA <213> HUMAN <400> 87 ctggtggcct ttaatacctg gctgttgctg aaaggtcttt agaaacggcg ctaacagcag 60 gtttgtggaa tgccggatcg ctcaacggcc tgacgtgggc aaaaacctcg ccttccgcac 120 ccatcattat attgatgctc attgccgccg ccttactggt acgccggatg cgcttgctgg 180 aaatgggaca cacggtcact gcagctgaag ccgctgcccc tgctacaggc accaccagga 240 ccagctgatc attccagccc acagcaatgg agccacatga ctcctcccac atggactctg 300 agttccgata cactctcttc ccgattgttt acagcatcat ctttgtgctc ggggtcattg 360 ctaatggcta cgtgctgtgg gtctttgccc gcctgtaccc ttgcaagaaa ttcaatgaga 420 taaagatctt catggtgaac ctcaccatgg cggacatgct cttcttgatc accctgccac 480 tttggattgt ctactaccaa aaccagggca actggatact ccccaaattc ctgtgcaacg 540 tggctggctg ccttttcttc atcaacacct actgctctgt ggccttcctg ggcgtcatca 600 cttataaccg cttccaggca gtaactcggc ccatcaagac tgctcaggcc aacacccgca 660 agcgtggcat ctctttgtcc ttggtcatct gggtggccat tgtgggagct gcatcctact 720 tcctcatcct ggactccacc aacacagtgc ccgacagtgc tggctcaggc aacgtcactc 780 gctgctttga gcattacgag aagggcagcg tgccagtcct catcatccac atcttcatcg 840 tgttcagctt cttcctggtc ttcctcatca tcctcttctg caacctggtc atcatccgta 900 ccttgctcat gcagccggtg cagcagcagc gcaacgctga agtcaagcgc cgggcgctgt 960 ggatggtgtg cacggtcttg gcggtgttca tcatctgctt cgtgccccac cacgtggtgc 1020 agctgccctg gacccttgct gagctgggct tccaggacag caaattccac caggccatta 1080 atgatgcaca tcaggtcacc ctctgcctcc ttagcaccaa ctgtgtctta gaccctgtta 1140 tctactgttt cctcaccaag aagttccgca agcacctcac cgaaaagttc tacagcatgc 1200 gcagtagccg gaaatgctcc cgggccacca cggatacggt cactgaagtg gttgtgccat 1260 tcaaccagat ccctggcaat tccctcaaaa attagtccct gcttccaggc ctgaagtctt 1320 ctcctccatg aacatcatgg actgagctgg gggaagaagg gatatctact gtggtctggg 1380 caccacctct gtgggcactg gtgggccatt agatttggag gctacctcac ctgggcaggg 1440 atgatggcag agccaggctg ttggaaaatc cagaactcaa atgagcccct tcatccgcct 1500 gtggggcata ctacagtaac tgtgacttga tgactttatc tgagtcctta t 1551 <210> 88 <211> 1071 <212> DNA <213> HUMAN <400> 88 gcagttctgg tcctcctagg agcggccgcc tgcgcggcgc ggccccgtgg tcggatgctg 60 ggcggcagag aggccgaggc gcacgcgcgg ccctacatgg cgtcggtgca gctgaacggc 120 gcgcacctgt gcgcaggcgt cctggtggcg gagcggtggg tgctgagcgc ggcgcactgc 180 ctggaggacg cggccgacgg gaaggtgcag gttctcctgg gcgcgcactc cctgtcgcag 240 ccggagccct ccaagcgcct gtacgacgtg ctccgcgcag tgccccaccc ggacagccag 300 cccgacacca tcgaccacga cctcctgctg ctacagctgt cggagaaggc cacactgggc 360 cctgctgtgc gccccctgcc ctggcagcgc gtggaccgcg acgtggcacc gggaactctc 420 tgcgacgtgg ccggctgggg catagtcaac cacgcgggcc gccgcccgga cagcctgcag 480 cacgtgctct tgccagtgct ggaccgcgcc acctgcaacc ggcgcacgca ccacgacggc 540 gccatcaccg agcgcttgat gtgcgcggag agcaatcgcc gggacagctg caagggtgac 600 tccgggggcc cgctggtgtg cgggggcgtg ctcgagggcg tggtcacctc gggctcgcgc 660 gtttgcggca accgcaagaa gcccgggatc tacacccgcg tggcgagcta tgcggcctgg 720 atcgacagcg tcctggccta gggtgccggg gcctgaaggt cagggtcacc caagcaacaa 780 agtcccgagc aatgaagtca tccactcctg catctggttg gtctttattg agcacctact 840 atatgcagaa ggggaggccg aggtgggagg atcattggat ctcaggagtt ggagatcagc 900 atgggccacg tagcgcgact ccatctctac aaataaataa aaattagctg ggcaattggc 960 gggcatggag gtgggtgctt gtagttccag ctactcagga ggctgaggtg ggaggatgac 1020 ttgaacgcag gaggctgagg ctgcagtgag ttgtgattgc accactgccc t 1071 <210> 89 <211> 653 <212> DNA <213> HUMAN <400> 89 acaggacaca gctgggttct gaagcttctg agttctgcag cctcaccctc tgagaaaacc 60 tcttttccac caataccatg aagctctgcg tgactgtcct gtctctcctc atgctagtag 120 ctgccttctg ctctccagcg ctctcagcac caatgggctc agaccctccc accgcctgct 180 gcttttctta cacccgagaa gcttcctcga actttgtggt agattactat gagaccagca 240 gcctctgctc ccagccagct gtggtattcc aaaccaaaag aagcaagcaa gtctgtgctg 300 atcccagtga atcctgggtc caggagtacg tgtatgacct ggaactgaac tgagctgctc 360 agagacagga agtcttcagg gaaggtcacc tgagcccgga tgcttctcca tgagacacat 420 ctcctccata ctcaggactc ctctccgcag ttcctgtccc ttctcttaat ttaatctttt 480 ttatgtgccg tgttattgta ttaggtgtca tttccattat ttatattagt ttagccaaag 540 gataagtgtc ccctatggat ggtccactgt cactgtttct ctgctgttgc aaatacatgg 600 ataacacatt tgattcgtgt gtgttttcat aataaaactt taaaataaaa tgc 653 <210> 90 <211> 775 <212> DNA <213> HUMAN <400> 90 gaattcccgg gcagcagaca gtggtcagtc ctttcttggc tctgctgaca ctcgagccca 60 cattccgtca cctgctcaga atcatgcagg tctccactgc tgcccttgct gtcctcctct 120 gcaccatggc tctctgcaac cagttctctg catcacttgc tgctgacacg ccgaccgcct 180 gctgcttcag ctacacctcc cggcagattc cacagaattt catagctgac tactttgaga 240 cgagcagcca gtgctccaag cccggtgtca tcttcctaac caagcgaagc cggcaggtct 300 gtgctgaccc cagtgaggag tgggtccaga aatatgtcag cgacctggag ctgagtgcct 360 gaggggtcca gaagcttcga ggcccagcga cctcggtggg cccagtgggg aggagcagga 420 gcctgagcct tgggaacatg cgtgtgacct ccacagctac ctcttctatg gactggttgt 480 tgccaaacag ccacactgtg ggactcttct taacttaaat tttaatttat ttatactatt 540 tagtttttgt aatttatttt cgatttcaca gtgtgtttgt gattgtttgc tctgagagtt 600 cccctgtccc ctcccccttc cctcacaccg cgtctggtga caaccgagtg gctgtcatca 660 gcctgtgtag gcagtcatgg caccaaagcc accagactga caaatgtgta tcggatgctt 720 ttgttcaggg ctgtgatcgg cctggggaaa taataaagat gctcttttaa aaggt 775 <210> 91 <211> 439 <212> DNA <213> HUMAN <400> 91 ccgcagcatg agctccgcag ccgggttctg cgcctcacgc cccgggctgc tgttcctggg 60 gttgctgctc ctgccacttg tggtcgcctt cgccagcgct gaagctgaag aagatgggga 120 cctgcagtgc ctgtgtgtga agaccacctc ccaggtccgt cccaggcaca tcaccagcct 180 ggaggtgatc aaggccggac cccactgccc cactgcccaa ctgatagcca cgctgaagaa 240 tggaaggaaa atttgcttgg acctgcaagc cccgctgtac aagaaaataa ttaagaaact 300 tttggagagt tagctactag ctgcctacgt gtgtgcattt gctatatagc atacttcttt 360 tttccagttt caatctaact gtgaaagaaa cttctgatat ttgtgttatc cttatgattt 420 taaataaaca aaataaatc 439 <210> 92 <211> 5191 <212> DNA <213> HUMAN <400> 92 gaattcagta acccaggcat tattttatcc tcaagtctta ggttggttgg agaaagataa 60 caaaaagaaa catgattgtg cagaaacaga caaacctttt tggaaagcat ttgaaaatgg 120 cattccccct ccacagtgtg ttcacagtgt gggcaaattc actgctctgt cgtactttct 180 gaaaatgaag aactgttaca ccaaggtgaa ttatttataa attatgtact tgcccagaag 240 cgaacagact tttactatca taagaaccct tccttggtgt gctctttatc tacagaatcc 300 aagacctttc aagaaaggtc ttggattctt ttcttcagga cactaggaca taaagccacc 360 tttttatgat ttgttgaaat ttctcactcc atcccttttg ctgatgatca tgggtcctca 420 gaggtcagac ttggtgtcct tggataaaga gcatgaagca acagtggctg aaccagagtt 480 ggaacccaga tgctctttcc actaagcata caactttcca ttagataaca cctccctccc 540 accccaacca agcagctcca gtgcaccact ttctggagca taaacatacc ttaactttac 600 aacttgagtg gccttgaata ctgttcctat ctggaatgtg ctgttctctt tcatcttcct 660 ctattgaagc cctcctattc ctcaatgcct tgctccaact gcctttggaa gattctgctc 720 ttatgcctcc actggaatta atgtcttagt accacttgtc tattctgcta tatagtcagt 780 ccttacattg ctttcttctt ctgatagacc aaactcttta aggacaagta cctagtctta 840 tctatttcta gatcccccac attactcaga aagttactcc ataaatgttt gtggaactga 900 tttctatgtg aagacatgtg ccccttcact ctgttaacta gcattagaaa aacaaatctt 960 ttgaaaagtt gtagtatgcc cctaagagca gtaacagttc ctagaaactc tctaaaatgc 1020 ttagaaaaag atttatttta aattacctcc ccaataaaat gattggctgg cttatcttca 1080 ccatcatgat agcatctgta attaactgaa aaaaaataat tatgccatta aaagaaaatc 1140 atccatgatc ttgttctaac acctgccact ctagtactat atctgtcaca tggtctatga 1200 taaagttatc tagaaataaa aaagcataca attgataatt caccaaattg tggagcttca 1260 gtattttaaa tgtatattaa aattaaatta ttttaaagat caaagaaaac tttcgtcata 1320 ctccgtattt gataaggaac aaataggaag tgtgatgact caggtttgcc ctgaggggat 1380 gggccatcag ttgcaaatcg tggaatttcc tctgacataa tgaaaagatg agggtgcata 1440 agttctctag tagggtgatg atataaaaag ccaccggagc actccataag gcacaaactt 1500 tcagagacag cagagcacac aagcttctag gacaagagcc aggaagaaac caccggaagg 1560 aaccattctc actgtgtgta aacatgactt ccaagctggc cgtggctctc ttggcagcct 1620 tcctgatttc tgcagctctg tgtgaaggta agcacatctt tctgacctac agcgttttcc 1680 tatgtctaaa tgtgatcctt agatagcaaa gctattcttg atgctttggt aacaaacatc 1740 ctttttattc agaaacagaa tataatctta gcagtcaatt aatgttaaat tgaagattta 1800 gaaaaaacta tatataacac ttaggaaata taaaggtttg atcaatatag atattctgct 1860 tttataattt ataccaggta gcatgcatat atttaacgta aataagtaat ttatagtatg 1920 tcctattgag aaccacggtt acctatatta tgtattaata ttgagttgag caaggtaact 1980 cagacaattc cactccttgt agtatttcat tgacaagcct cagatttgtc attaattcct 2040 gtctggttta aagataccct gattatagac caggcatgta taacttattt atatatttct 2100 gttaattctt tctgaaggca atttctatgc tggagagtct tagcttgcct actataaata 2160 acactgtggt atcacagagg attatgcaat attgaccaga taaaaatacc atgaagatgt 2220 tgatattgta caaaaagaac tctaactctt atataggaag ttgttcaatg ttgtcagtta 2280 tgactgtttt ttaaaacaaa gaactaactg aggtcaaggg ctaggagata ttcaggaatg 2340 agttcactag aaacatgatg ccttccatag tctccaaata atcatattgg aattagaagg 2400 aagtagctgg cagagctgtg cctgttgata aaatcaatcc ttaatcactt tttcccccaa 2460 caggtgcagt tttgccaagg agtgctaaag aacttagatg tcagtgcata aagacatact 2520 ccaaaccttt ccaccccaaa tttatcaaag aactgagagt gattgagagt ggaccacact 2580 gcgccaacac agaaattatg taagtacttt aaaaaagatt agatattttg ttttagcaaa 2640 cttaaaatta aggaaggtgg aaatatttag gaaagttcca ggtgttagga ttacagtagt 2700 aaatgaaaca aaacaaaata aaaatatttg tctacatgac atttaaatat ggtagcttcc 2760 acaactacta taaatgttat tttggactta gactttatgc ctgacttaag gaatcatgat 2820 ttgaatgcaa aaactaaata ttaatctgaa ccatttcttt cttatttcag tgtaaagctt 2880 tctgatggaa gagagctctg tctggacccc aaggaaaact gggtgcagag ggttgtggag 2940 aagtttttga agaggtaagt tatatatttt ttaatttaaa tttttcattt atcctgagac 3000 atataatcca aagtcagcct ataaatttct ttctgttgct aaaaatcgtc attaggtatc 3060 tgcctttttg gttaaaaaaa aaggaatagc atcaatagtg agtttgttgt acttatgacc 3120 agaaagacca tacatagttt gcccaggaaa ttctgggttt aagcttgtgt cctatactct 3180 tagtaaagtt ctttgtcact cccagtagtg tcctatttta gatgataatt tctttgatct 3240 ccctatttat agttgagaat atagagcatt tctaacacat gaatgtcaaa gactatattg 3300 acttttcaag aaccctactt tccttcttat taaacatagc tcatctttat atttttaatt 3360 ttattttagg gctgagaatt cataaaaaaa ttcattctct gtggtatcca agaatcagtg 3420 aagatgccag tgaaacttca agcaaatcta cttcaacact tcatgtattg tgtgggtctg 3480 ttgtagggtt gccagatgca atacaagatt cctggttaaa tttgaatttc agtaaacaat 3540 gaatagtttt tcattgtacc atgaaatatc cagaacatac ttatatgtaa agtattattt 3600 atttgaatct acaaaaaaca acaaataatt tttaaatata aggattttcc tagatattgc 3660 acgggagaat atacaaatag caaaattggg ccaagggcca agagaatatc cgaactttaa 3720 tttcaggaat tgaatgggtt tgctagaatg tgatatttga agcatcacat aaaaatgatg 3780 ggacaataaa ttttgccata aagtcaaatt tagctggaaa tcctggattt ttttctgtta 3840 aatctggcaa ccctagtctg ctagccagga tccacaagtc cttgttccac tgtgccttgg 3900 tttctccttt atttctaagt ggaaaaagta ttagccacca tcttacctca cagtgatgtt 3960 gtgaggacat gtggaagcac tttaagtttt ttcatcataa cataaattat tttcaagtgt 4020 aacttattaa cctatttatt atttatgtat ttatttaagc atcaaatatt tgtgcaagaa 4080 tttggaaaaa tagaagatga atcattgatt gaatagttat aaagatgtta tagtaaattt 4140 attttatttt agatattaaa tgatgtttta ttagataaat ttcaatcagg gtttttagat 4200 taaacaaaca aacaattggg tacccagtta aattttcatt tcagatatac aacaaataat 4260 tttttagtat aagtacatta ttgtttatct gaaattttaa ttgaactaac aatcctagtt 4320 tgatactccc agtcttgtca ttgccagctg tgttggtagt gctgtgttga attacggaat 4380 aatgagttag aactattaaa acagccaaaa ctccacagtc aatattagta atttcttgct 4440 ggttgaaact tgtttattat gtacaaatag attcttataa tattatttaa atgactgcat 4500 ttttaaatac aaggctttat atttttaact ttagtgtttt tatgtgctct ccaaattttt 4560 tttactgttt ctgattgtat ggaaatataa aagtaaatat gaaacattta aaatataatt 4620 tgttgtcaaa gtaatcaagt gtttgtcttt tttttagttt tagcttattg ggattctctt 4680 tgtttatatt taaaattata ctttgattta gaaaacataa atgcttcccc ttagcatttt 4740 gttatggaaa attacaaact tttattttta gaaaacagaa ctcctttcca gaaataggtt 4800 acaaacagta gtgtcctcca cagaatgttg gaaatgtttt caactcccca ctgtatacta 4860 tcttgctaat aagtctgtct tcagatttcg attaaccggt ttgtatgtct gtgcacttta 4920 gcatagctgg acattaaaga ggaaagagag tacatattat aagttgctta tcagtaactg 4980 aggagtaaaa ctgataaatg tgaggcaaag aagtttaaaa tatggttaaa gcctaagcat 5040 atttgcaaac aaatcaaaca atactctgag aagtaaaaac ataattattt aattaacaaa 5100 tttcagtgga taaattttat aacaaattag acacagttga aaataaaatt agaaaactag 5160 aaaatagaac aaaagaaact tctggaattc a 5191 <210> 93 <211> 4206 <212> DNA <213> HUMAN <400> 93 gtcgacacca cccaaaatag tgccgagcct cttggggggg gaggggctgg gagtgggggc 60 cctgagtgag agcaacgagg gtgtgaccag cgccgcccgg acccctagtc ccctcccccg 120 cacactcttc agctgtcgca gggggcctga gaggacagct gagggtcctg gctgggaacg 180 agctggggag ggggagctgg tggtgcctgg ggcatgaaga ggcctcgctg agaccctcac 240 aaacggtttg cacgtttcca cacctcattt tctcctcttc ggtggcaggc actgtgcacc 300 caattcctaa agcactcctg gatttaatgt tctgagagcc acatagaacg aaagatgcaa 360 gaaatctgtt tgctcttttt tcagggggtg gggtctttct gcccagatgt gggatcctct 420 cctaaaccca ggtcaaccca gggcacgagg cagatggctg gtgctgacat gttgaccatc 480 actgctctct tccaaggact cacaaagagt taatgtccct ggggctcagc ctaggaagat 540 tccagtccct gcccaggccc aagatagttg ctggcctgat tcccctggca ttcaggactg 600 gaaaggagga ggaggggcac actacgccgg ctcccatcct ccccccaccc cgcgtgcctg 660 cttgggattc ctgactctgt accagcttca gagaacaggg gtgggggtgg gtgccattgg 720 gtgtggacag aaagctagtg aaacaagacc atgacaagtc actggccggc tcagacgtgt 780 ttgtgtctct cttttcttag ctcagtgagt actgggtatg tgtcacattg ccaaatcccg 840 gatcacaagt ctccatgaac tgctggtgag ctaggataat aaaacccctg acatcaccat 900 tccagaagct tcacaagact gcatatataa ggggctggct gtagctgcag ctgaaggagc 960 tgaccagcca gctgacccct cacactcacc tagccaccat ggacatcgcc atccaccacc 1020 cctggatccg ccgccccttc tttcctttcc actcccccag ccgcctcttt gaccagttct 1080 tcggagagca cctgttggag tctgatcttt tcccgacgtc tacttccctg agtcccttct 1140 accttcggcc accctccttc ctgcgggcac ccagctggtt tgacactgga ctctcagagg 1200 tgagtctccc cacagctagg acgggagagt ccttactgga acctcctgga aacttctcca 1260 tccattttcc tttcctaccc tgcctaaacc attttaggca catgtgtgtc caaatgtgaa 1320 gaaaaatgag gaggttgcta gtgccttcct cccccatcac ctgtttctat ttgatagtcc 1380 tctgtatccc atttattaca ttttttcatg cactgtcaag tttatcctcc gtcccctaac 1440 ttctctacag gatacccctt tctggtttgg ttcatgacaa tctgcaggga aagagctgcc 1500 ttcaaactcc tttgcttatc tcttccaaca ccttggactc ttgaccgatt ttaccatctc 1560 aggtttcaga gccaggagag agccctgcct catcctgagc tgttcatccc catgggtatt 1620 ttctgccttt ctattccctc ttctatgatt ttctgggttt ctcagggcta cgacagggcg 1680 ctggcctggg tccaatcaag ccctacgagg aaacaatata gggacgccca tttgtcctaa 1740 gagggtggaa gaacagggtg aacaaataag gttgacagag ctgtcacaga taacactctg 1800 gtttaaaaat attcaagtgt gagtaaacag gagctgagtg ggcaagggct ttggaaggac 1860 aagcaggacc agcagaacat tccagattgg gtgggtggaa aactggcaaa gagacctgag 1920 ccagaagaag aggcctttgt ctcacagaca aaccacaaag ccaggcattg gagtcagaga 1980 ggcagcagat gccaggcttg cacccatcct tgcgactggt cccctgggtg atctgtcttc 2040 ttctctgtcc ctgtaaataa agtttgggtc tgatcaccat gagccttagg tatcactgtg 2100 gtggctccct gaagcagaca gctatgttta tttaaaaagg agatttttta agcagagaag 2160 agaaggatga attacccgga cagaaagcag ctctgcagaa taagacagca cctgtgtaat 2220 cagtattttt gccctctttc tcccatccca ttcccttacc ttgctatttc tagatgcgcc 2280 tggagaagga caggttctct gtcaacctgg atgtgaagca cttctcccca gaggaactca 2340 aagttaaggt gttgggagat gtgattgagg tgcatggaaa acatgaagag cgccaggtat 2400 gtagcttgtt tttttgtttt ctgctcattc attcagtgat actgtaatag tccaggtagt 2460 gctatcagct ttggaggctg gctacattcc agtcccaagc cataacagtc gggatcaggg 2520 gttacaaatc aatgtctaga agactaagtt aggatagaca tattgctgtt gttactatta 2580 tggccagaga tgtggccttt gatttgatcg ccttagatgg gatgatggga tgctgatgcc 2640 ccatttaagc cagtggttct gaatctgggc cacattagaa tcaccagggg aactttcaaa 2700 aacctaatgc tcgggcatcc tccagaccaa ttagcatatg tgctgccgaa gcgagcacta 2760 ctccagacca attaaatcag catttttaag ggtgggaccc aggcatcagc aatttttaag 2820 gtaattctaa tctacagtca aggttgagaa ccactgatta ggtatagggc tgtcagacac 2880 ctagttgctt tgcataatta cattaactac aggtacccta aaagcacttg agttgtgact 2940 tctcttttag ctgtgcaaga atccgtgtct cttctttagc ccatcttaat gctgaactac 3000 ttggtttgtc taaatttcag agctgtgctc agtctttaat cccctacagc ccatgtggta 3060 atcagttaac gagagcctgt ttggctacat gcttgagagt cagcaggcat acgggttaag 3120 gtcatctact ctttggggga gttctgacaa atggaacagc ttgttatgac tttataagag 3180 ggctttaaaa ttgcttctca ccatttaacg atagctcaga acctgtgcgt caaccagtac 3240 agtttgtcct cagtaatgtc ctcaggctgt ttcaattttg cttatatgat ttaggtttgg 3300 gtcatagtct ccttggatgg agtcattttt tttttttttt aatttcagca gcagtcctat 3360 tgttctggaa ccttctggga cattcctgaa gagtcaggac aatttcaggg cttcctcagg 3420 gactcagatt ctaaatgaga ttccaaattc tgtaggccca gccaacattg atctaaacct 3480 ttgggaaata cccctaaaca tatctatgcc tcagggtttg aaaaacaatg aagtgttgga 3540 ctgtttcaga cttctcagat tctcactggt aggagtgact acctaggcaa tttcatctta 3600 gctgcaaccc tgaaacgaag ctctatttat ttttcctatg ttgtcatggc atttggtctc 3660 acctaagggg aaatcaggat gcctgagttc tgggcaggtg ataatagttc ctgttcttat 3720 ctctctgcct ctttcctcat tcttttgggt taggatgaac atggtttcat ctccagggag 3780 ttccacagga aataccggat cccagctgat gtagaccctc tcaccattac ttcatccctg 3840 tcatctgatg gggtcctcac tgtgaatgga ccaaggaaac aggtctctgg ccctgagcgc 3900 accattccca tcacccgtga agagaagcct gctgtcaccg cagcccccaa gaaatagatg 3960 ccctttcttg aattgcattt tttaaaacaa gaaagtttcc ccaccagtga atgaaagtct 4020 tgtgactagt gctgaagctt attaatgcta agggcaggcc caaattatca agctaataaa 4080 atatcattca gcaacagata actgtcttgt gtttgaatat tccacacact tttaaataaa 4140 tatacagata ccacagatct atttatgatt gcattatgat ttagagggct ccaaggattt 4200 tagagt 4206 <210> 94 <211> 6192 <212> DNA <213> HUMAN <400> 94 agaggctgcg gtgagtccgc cagccccagc tgctcctcct caagccccca aggcccttcg 60 gcgggcccct gctgaaagac cggcatgccc tattctgtgg gcttccgcga agccgatgct 120 gctaccagct ttctgagagc agcaagatca ggtaacttgg acaaagcttt ggatcacctg 180 cggaatgggg tagatattaa cacctgtaac cagaatgggt tgaatggctt gcatctggct 240 tctaaggaag gccatgtgaa aatggtggtt gaacttctgc acaaagaaat cattctagaa 300 acgacaacca agaaggggaa cacggccctg cacatcgctg ctctagccgg gcaggatgag 360 gtggtccggg agcttgtcaa ctatggagcc aacgtcaatg cccagtcaca gaaaggtttt 420 acacccctgt acatggcagc acaagagaac cacttggaag tggttaagtt tttactggaa 480 aatggagcta accagaatgt agccacagaa gacggcttca cgcctctggc ggtagccctg 540 cagcagggcc atgagaacgt cgtcgcgcac ctcatcaact acggcaccaa ggggaaggtg 600 cgcctcccgg ccctgcacat cgcggcccgc aacgacgaca cgcgcacggc tgcggtgctg 660 ctgcagaacg accccaaccc ggacgtgctt tccaagacgg gattcacgcc cctgcacatt 720 gcggctcact acgagaacct caacgtggcc cagttgctcc tcaacagagg cagcagcgtc 780 aatttcacac cacagaacgg catcacgcca ctgcacatcg cctcccgcag gggcaacgtg 840 atcatggtgc ggctgctgct ggatcgggga gcccagatag aaaccaagac caaggacgaa 900 ttgacacctc tccactgtgc agctcgaaat gggcacgtgc gaatctcaga gatcctgctg 960 gaccacgggg caccaatcca agccaaaacc aagaacggcc tgtccccaat tcacatggcg 1020 gctcagggag accacctcga ctgtgtccgg ctcctgttgc aatacgacgc agagatagac 1080 gacatcaccc tggaccacct gaccccactc cacgtggctg cccactgtgg acaccacagg 1140 gtggctaagg tccttctgga taaaggggcc aaacccaact ccagagccct gaatggcttt 1200 acccccttac acatcgcctg caaaaagaac cacgtccgtg tcatggagct gctgctgaag 1260 acgggagcct cgatcgacgc ggtcaccgag tctggcctga cacctctcca cgtggcctcc 1320 ttcatggggc accttcccat cgtgaagaac ctcctgcagc ggggggcgtc gcccaacgtc 1380 tccaacgtga aagtggagac cccgctacac atggcagcca gagccgggca cacggaagtg 1440 gccaaatatt tactccagaa caaagccaaa gtcaatgcca aggccaagga tgaccagacc 1500 ccacttcact gtgcagctcg catcggccac acaaacatgg tgaagctcct gctggaaaat 1560 aacgccaacc ccaacctggc caccaccgcc gggcacaccc ccctgcacat tgcagcccgt 1620 gagggccatg tggaaacagt cctggccctt ctggaaaagg aagcatccca ggcctgcatg 1680 accaagaaag gatttacccc tctgcacgtg gcggccaagt acgggaaggt gcgggtggca 1740 gagctgctgc tggagcggga cgcacacccg aatgctgccg gaaaaaatgg cctgaccccc 1800 ctgcacgtgg ccgtccatca caacaacctg gacatcgtca agctgctgct tccccggggc 1860 ggctccccgc acagccctgc ctggaatggc tacacccctt tgcacatcgc tgccaagcag 1920 aaccaggtgg aggtggcccg tagtctgctg cagtatgggg gctcagcaaa cgccgagtcg 1980 gtgcaaggtg tgacgcccct tcacctggcc gcccaggagg gccacgcaga gatggtggct 2040 ctgctgctct cgaaacaagc caatggcaac ctggggaaca agagcggact cactcccctc 2100 catctggtag cacaagaagg ccacgttcca gtggcagatg tgctgatcaa acacggcgtc 2160 atggtggacg ccaccacccg gatgggctac actcccctcc atgtggccag tcactatgga 2220 aacatcaagc tggtgaagtt tctgctgcag caccaggcag atgtcaatgc caagaccaag 2280 ctaggataca gccccctgca ccaggcagcc cagcagggac acacagacat cgtgactctg 2340 cttctgaaaa acggtgcttc cccaaacgag gtcagctcgg atggaaccac acctctggcc 2400 atagccaagc gcttgggcta catttctgtc accgacgtgc tcaaggtcgt cacggatgaa 2460 accagtttcg tgttagtcag tgataagcat cgaatgagtt tccctgagac agttgatgag 2520 atcctggatg tctcggaaga tgaaggggaa gaactcatca gcttcaaggc tgagaggcgg 2580 gattccaggg atgttgatga agagaaggag ctgctggatt ttgtgccgaa gctagaccaa 2640 gtggtggaat ctccagccat ccccaggatt ccctgtgcca tgcctgagac agtggtgatc 2700 aggtcagaag agcaggagca ggcatctaaa gagtatgatg aggactccct catccccagc 2760 agcccggcca ccgagacctc agacaacatc agcccggtgg ccagcccggt gcatacaggg 2820 tttctggtga gcttcatggt tgacgcccgg ggtggttcca tgagaggaag tcgccacaac 2880 ggcctgcgag tggtgatccc gccacggacg tgcgcagcgc ccacccgcat cacctgccgc 2940 ctggtcaagc cccagaagct cagcacgccg cccccactgg ccgaggagga gggcctggcc 3000 agcaggatca tagcactggg gcccacgggc gcacagttcc tgagccctgt aatcgtggag 3060 atcccgcact ttgcctccca tggccgtgga gaccgcgagc tcgtggttct gaggagcgaa 3120 aacggctccg tgtggaagga gcacaggagc cgctatggag agagctacct ggatcagatc 3180 ctcaacggga tggacgaaga gctggggagc ctggaggagc tagagaagaa gagggtgtgc 3240 cgaatcatca ccaccgactt cccgctgtac ttcgtgatca tgtcacggct ctgccaggac 3300 tacgacatca tcggtcccga agggggctcc ctgaagagca agctggtgcc cctggtacag 3360 gcaacgttcc cggagaatgc cgtcaccaag agagtgaagc tggctctgca ggcccagcct 3420 gtcccggatg agcttgtcac taagctcctg ggcaaccagg ccacattcag ccccattgtc 3480 accgtggagc cccggcgccg gaagttccac cgccccattg ggcttcggat cccactacct 3540 ccttcctgga ccgacaaccc gagggacagt ggggagggag acaccaccag cctgcgcctg 3600 ctttgcagcg tcattggagg aacagaccaa gcccagtggg aagacataac aggaaccacc 3660 aaacttgtat atgccaacga gtgcgccaac ttcaccacca atgtctctgc caggttttgg 3720 ctgtcggact gtcctcggac tgctgaggct gtgaactttg ccaccctgct gtacaaagag 3780 ctcactgcag tgccctacat ggccaaattc gtcatctttg ccaagatgaa tgacccccga 3840 gaggggcgcc tgcgctgcta ctgcatgaca gatgataaag tggacaagac cctggagcag 3900 catgagaact tcgtggaggt ggcccggagc agggacatag aggtgttgga aggaatgtcc 3960 ctgtttgcag aactctctgg gaacctggtg cctgtgaaga aagctgccca gcagcggagc 4020 ttccacttcc agtcatttcg ggagaaccgt ctggccatgc ctgtaaaggt gagggacagc 4080 agtcgagagc cgggagggtc cctgtcgttt ctgcgcaagg cgatgaagta cgaggacacc 4140 cagcacattc tctgccacct gaacatcacc atgcccccct gcgctaaggg aagtggagcc 4200 gaagatagga gaaggacccc gacgcccctg gccctgcgat acagcattct cagtgagtcc 4260 acaccaggtt ctctcagtgg gacagagcag gcagagatga agatggctgt tatctcagag 4320 cacctcggtc tcagctgggc agagttggcc cgggagctgc agttcagtgt ggaagacatc 4380 aacaggatcc gagtggaaaa tcccaactcc ctgttggagc agagtgtggc cttgctgaac 4440 ctctgggtca tccgtgaagg ccaaaacgca aacatggaga atctgtacac agccctgcag 4500 agcattgacc gtggcgagat cgtgaacatg ctggagggtt ccggccgaca gagccgcaac 4560 ttgaagccag acaggcggca caccgaccgc gactactcgc tgtcaccctc ccagatgaat 4620 ggttactcct cactgcagga cgagctgctg tcccctgcct ccctgggctg tgcactttcc 4680 tctccgctac gtgcagacca gtactggaat gaggtggcca tcctagacgc catccccttg 4740 gcggccacgg agcatgacac catgctggag atgtctgaca tgcaggtgtg gtctgcgggc 4800 ctcacgcctt ctctggtcac tgctgaggac tcctctctgg agtgtagcaa ggctgaggac 4860 tctgatgcca caggtcacga gtggaagttg gagggggcac tctcagagga accgcggggc 4920 cccgagttgg gctctctgga acttgtggag gacgacacag tggattcaga tgccacaaat 4980 ggccttatcg atttgcttga acaggaggaa ggtcagaggt cagaagagaa gctgccaggt 5040 tctaagaggc aggatgacgc gacaggtgca gggcaggact cagagaatga agtgtctctt 5100 gtttcaggcc atcagagggg gcaagcccga atcacacatt cccccaccgt gagtcaggtg 5160 acggagagga gtcaggacag actgcaggac tgggatgcag acggctcgat tgtctcatac 5220 ctgcaagatg ctgcacaagg ttcctggcaa gaggaggtca cgcaaggtcc acactcattc 5280 cagggaacaa gtaccatgac tgaagggcta gagcccggtg gatctcagga gtacgagaag 5340 gtcctggtgt ctgtaagtga gcacacgtgg acagaacagc ccgaggctga gagctcccag 5400 gccgacaggg accggaggca gcaaggccaa gaagagcagg tgcaggaggc caagaacacc 5460 ttcacccaag tggtgcaggg gaatgagttt cagaatattc caggggagca ggtgacagag 5520 gagcaattca cggatgagca gggcaacatt gtcaccaaga agatcattcg caaggtggtt 5580 cgacagatag acttgtccag cgccgatgcc gcccaggagc acgaggaggt ggagctgaga 5640 gggagtggcc tacagccgga cctgatagag ggcaggaagg gggcgcagat agtgaagcgg 5700 gccagcctga aaagggggaa acagtgaccc cgagccgctc tccttggagt agcctctcgg 5760 gaggatcaca cctcgacacc caacccctga accccacaca ctctgccatg cacacaggag 5820 gagagctgga cctgagggcc accgcagcgg tgcacacatt cctctgggct gacggcatga 5880 cctctgtaag ggactcctgc tagtcccctc ttggcatgaa tgactgactg tagacgcatg 5940 acctccaggc ttcaatcctg cctcttgcaa tgacagctga tctgtcggaa ccaggacaca 6000 aaagcagcaa gaagcgggga gagagaggga tagaaaacaa gcgcaggaga gcctgcgaac 6060 gcaaaagtga atgagggctt tttgtggctg gggatgggtt ttggttttgg ggtttttttt 6120 ttaaattgtt ttgacttcgt acagggtact ttttcccggc ctcatctgtc agaaatccat 6180 gtgggcttcc tg 6192 <210> 95 <211> 681 <212> DNA <213> HUMAN <400> 95 gaattcagtt caatgtttac acaatcctac agttctgcta ggcttctatg atgctactat 60 tctgcatttg aatgagcaaa tggatttaat gcattgtcag ggagccggcc aaagcttgag 120 agctccttcc tggctgggag gccccttgga atgtggcctg aaggtaagct ggcagcgagc 180 ctgacatgct ttcatctagt ttcctcgctt ccttcctttt ctgcagtttt cgcttcacag 240 aaagcagaat ccttaaaaat aaccctctta gttcacatct gtggtcagtc tgggcttaat 300 ggcaccccat cctccccatt tgctcatttg gtctcagcag tgaatggaaa aagtgtctcg 360 tcctgacccc ctgcttccct ttcctacttc ctggaaatcc acaggatgct gcatttgctc 420 agcagattta acagcccact tatcactcat ggaagatccc tcctcctgct tgactccgcc 480 ctctctccct ctgcccgctt tcaataagag gcagagacag cagccagagg aaccgagagg 540 ctgagactaa cccagaaaca tccaattctc aaactgaagc tcgcactctc gcctccagca 600 tgaaagtctc tgccgccctt ctgtgcctgc tgctcatagc agccaccttc attccccaag 660 ggctcgctca gccaggtagg c 681 <210> 96 <211> 128 <212> DNA <213> HUMAN <400> 96 tccagatgca atcaatgccc cagtcacctg ctgctataac ttcaccaata ggaagatctc 60 agtgcagagg ctcgcgagct atagaagaat caccagcagc aagtgtccca aagaagctgt 120 gatgtgag 128 <210> 97 <211> 482 <212> DNA <213> HUMAN <400> 97 cacagcttca agaccattgt ggccaaggag atctgtgctg accccaagca gaagtgggtt 60 caggattcca tggaccacct ggacaagcaa acccaaactc cgaagacttg aacactcact 120 ccacaaccca agaatctgca gctaacttat tttcccctag ctttccccag acaccttgtt 180 ttattttatt ataatgaatt tgtttgttga tgtgaaacat tatgccttaa gtaatgttaa 240 ttcttattta agttattgat gttttaagta tctttcatgg tactagtgtt ttttagatac 300 agagacttgg ggaaattgct tttcctcttt tgaaccacag ttctacccct gggatgtttt 360 gagggtcttt gcaagaatca ttaatacaaa gaattttttt taacattcca atgcattgct 420 aaaatattat tgtggaaatg aatattttgt aactattaca ccaaataaat atatttttgt 480 ac 482 <210> 98 <211> 3328 <212> DNA <213> HUMAN <400> 98 ccggccgcgg agctcttgcg accccgccag gacccgaaca gagcccgggg gcggcgggcc 60 ggagccgggg acgcgggcac acgcccgctc gcacaagcca cggcggactc tcccgaggcg 120 gaacctccac gccgagcgag ggtcagtttg aaaaggagga tcgagctcac tgtggagtat 180 ccatggagat gtggagcctt gtcaccaacc tctaactgca gaactgggat gtggagctgg 240 aagtgcctcc tcttctgggc tgtgctggtc acagcaacac tctgcaccgc taggccgtcc 300 ccgaccttgc ctgaacaaga tgctctcccc tcctcggagg atgatgatga tgatgatgac 360 tcctcttcag aggagaaaga aacagataac accaaaccaa accccgtagc tccatattgg 420 acatccccag aaaagatgga aaagaaattg catgcagtgc cggctgccaa gacagtgaag 480 ttcaaatgcc cttccagtgg gaccccaaac cccacactgc gctggttgaa aaatggcaaa 540 gaattcaaac ctgaccacag aattggaggc tacaaggtcc gttatgccac ctggagcatc 600 ataatggact ctgtggtgcc ctctgacaag ggcaactaca cctgcattgt ggagaatgag 660 tacggcagca tcaaccacac ataccagctg gatgtcgtgg agcggtcccc tcaccggccc 720 atcctgcaag cagggttgcc cgccaacaaa acagtggccc tgggtagcaa cgtggagttc 780 atgtgtaagg tgtacagtga cccgcagccg cacatccagt ggctaaagca catcgaggtg 840 aatgggagca agattggccc agacaacctg ccttatgtcc agatcttgaa gactgctgga 900 gttaatacca ccgacaaaga gatggaggtg cttcacttaa gaaatgtctc ctttgaggac 960 gcaggggagt atacgtgctt ggcgggtaac tctatcggac tctcccatca ctctgcatgg 1020 ttgaccgttc tggaagccct ggaagagagg ccggcagtga tgacctcgcc cctgtacctg 1080 gagatcatca tctattgcac aggggccttc ctcatctcct gcatggtggg gtcggtcatc 1140 gtctacaaga tgaagagtgg taccaagaag agtgacttcc acagccagat ggctgtgcac 1200 aagctggcca agagcatccc tctgcgcaga caggtaacag tgtctgctga ctccagtgca 1260 tccatgaact ctggggttct tctggttcgg ccatcacggc tctcctccag tgggactccc 1320 atgctagcag gggtctctga gtatgagctt cccgaagacc ttcgctggga gctgcctcgg 1380 gacagactgg tcttaggcaa acccctggga gagggctgct ttgggcaggt ggtgttggca 1440 gaggctatcg ggctggacaa ggacaaaccc aaccgtgtga ccaaagtggc tgtgaagatg 1500 ttgaagtcgg acgcaacaga gaaagacttg tcagacctga tctcagaaat ggagatgatg 1560 aagatgatcg ggaagcataa gaatatcatc aacctgctgg gggcctgcac gcaggatggt 1620 cccttgtatg tcatcgtgga gtatgcctcc aagggcaacc tgcgggagta cctgcaggcc 1680 cggaggcccc cagggctgga atactgctac aaccccagcc acaacccaga ggagcagctc 1740 tcctccaagg acctggtgtc ctgcgcctac caggtggccc gaggcatgga gtatctggcc 1800 tccaagaagt gcatacaccg agacctggca gccaggaatg tcctggtgac agaggacaat 1860 gtgatgaaga tagcagactt tggcctcgca cgggacattc accacatcga ctactataaa 1920 aagacaacca acggccgact gcctgtgaag tggatggcac ccgaggcatt atttgaccgg 1980 atctacaccc accagagtga tgtgtggtct ttcggggtgc tcctgtggga gatcttcact 2040 ctgggcggct ccccataccc cggtgtgcct gtggaggaac ttttcaagct gctgaaggag 2100 ggtcaccgca tggacaagcc cagtaactgc accaacgagc tgtacatgat gatgcgggac 2160 tgctggcatg cagtgccctc acagagaccc accttcaagc agctggtgga agacctggac 2220 cgcatcgtgg ccttgacctc caaccaggag tacctggacc tgtccatgcc cctggaccag 2280 tactccccca gctttcccga cacccggagc tctacgtgct cctcagggga ggattccgtc 2340 ttctctcatg agccgctgcc cgaggagccc tgcctgcccc gacacccagc ccagcttgcc 2400 aatggcggac tcaaacgccg ctgactgcca cccacacgcc ctccccagac tccaccgtca 2460 gctgtaaccc tcacccacag cccctgctgg gcccaccacc tgtccgtccc tgtccccttt 2520 cctgctggca ggagccggct gcctaccagg ggccttcctg tgtggcctgc cttcacccca 2580 ctcagctcac ctctccctcc acctcctctc cacctgctgg tgagaggtgc aaagaggcag 2640 atctttgctg ccagccactt catcccctcc agatgttgga ccaacacccc tccctgccac 2700 caggcatctg ccggatgggc agagtggagc aatgaacagg catgcaagtg agagcttcct 2760 gagctttctc ctgtcggttt ggtctgtttt gccttcaccc ataagcccct cgcactctgg 2820 tggcaggtgc ttgtcctcag ggctacagca gtagggaggt cagtgcttcg tgcctcgatt 2880 gaaggtgacc tctgccccag ataggtggtg ccagtggctt attaattccg atactagttt 2940 gctttgctga ccaaatgcct ggtaccagag gatggtgagg cgaaggccag gttgggggca 3000 gtgttgtgcc ctggcccagc caaactgggg gctctgtggg ggctctgtat atagctatga 3060 agaaaacaca aagtgtataa atctgagtat atatttacat gtctttttaa aagggtcgtt 3120 accagagatt tacccatcgg gtaagatgct cctggtggct gggaggcatc agttgctata 3180 tattaaaaac aaaaaagaaa aaaaaggaaa atgtttttaa aaaggtcata tattttttgc 3240 tacttttgct gttttatttt tttaaattat gttctaaacc tattttcagt ttaggtccct 3300 caataaaaat tgctgctgct taaaaacc 3328 <210> 99 <211> 4788 <212> DNA <213> HUMAN <400> 99 tttttagaaa aaaaaaatat atttccctcc tgctccttct gcgttcacaa gctaagttgt 60 ttatctcggc tgcggcggga actgcggacg gtggcgggcg agcggctcct ctgccagagt 120 tgatattcac tgatggactc caaagaatca ttaactcctg gtagagaaga aaaccccagc 180 agtgtgcttg ctcaggagag gggagatgtg atggacttct ataaaaccct aagaggagga 240 gctactgtga aggtttctgc gtcttcaccc tcactggctg tcgcttctca atcagactcc 300 aagcagcgaa gacttttggt tgattttcca aaaggctcag taagcaatgc gcagcagcca 360 gatctgtcca aagcagtttc actctcaatg ggactgtata tgggagagac agaaacaaaa 420 gtgatgggaa atgacctggg attcccacag cagggccaaa tcagcctttc ctcgggggaa 480 acagacttaa agcttttgga agaaagcatt gcaaacctca ataggtcgac cagtgttcca 540 gagaacccca agagttcagc atccactgct gtgtctgctg cccccacaga gaaggagttt 600 ccaaaaactc actctgatgt atcttcagaa cagcaacatt tgaagggcca gactggcacc 660 aacggtggca atgtgaaatt gtataccaca gaccaaagca cctttgacat tttgcaggat 720 ttggagtttt cttctgggtc cccaggtaaa gagacgaatg agagtccttg gagatcagac 780 ctgttgatag atgaaaactg tttgctttct cctctggcgg gagaagacga ttcattcctt 840 ttggaaggaa actcgaatga ggactgcaag cctctcattt taccggacac taaacccaaa 900 attaaggata atggagatct ggttttgtca agccccagta atgtaacact gccccaagtg 960 aaaacagaaa aagaagattt catcgaactc tgcacccctg gggtaattaa gcaagagaaa 1020 ctgggcacag tttactgtca ggcaagcttt cctggagcaa atataattgg taataaaatg 1080 tctgccattt ctgttcatgg tgtgagtacc tctggaggac agatgtacca ctatgacatg 1140 aatacagcat ccctttctca acagcaggat cagaagccta tttttaatgt cattccacca 1200 attcccgttg gttccgaaaa ttggaatagg tgccaaggat ctggagatga caacttgact 1260 tctctgggga ctctgaactt ccctggtcga acagtttttt ctaatggcta ttcaagcccc 1320 agcatgagac cagatgtaag ctctcctcca tccagctcct caacagcaac aacaggacca 1380 cctcccaaac tctgcctggt gtgctctgat gaagcttcag gatgtcatta tggagtctta 1440 acttgtggaa gctgtaaagt tttcttcaaa agagcagtgg aaggacagca caattaccta 1500 tgtgctggaa ggaatgattg catcatcgat aaaattcgaa gaaaaaactg cccagcatgc 1560 cgctatcgaa aatgtcttca ggctggaatg aacctggaag ctcgaaaaac aaagaaaaaa 1620 ataaaaggaa ttcagcaggc cactacagga gtctcacaag aaacctctga aaatcctggt 1680 aacaaaacaa tagttcctgc aacgttacca caactcaccc ctaccctggt gtcactgttg 1740 gaggttattg aacctgaagt gttatatgca ggatatgata gctctgttcc agactcaact 1800 tggaggatca tgactacgct caacatgtta ggagggcggc aagtgattgc agcagtgaaa 1860 tgggcaaagg caataccagg tttcaggaac ttacacctgg atgaccaaat gaccctactg 1920 cagtactcct ggatgtttct tatggcattt gctctggggt ggagatcata tagacaatca 1980 agtgcaaacc tgctgtgttt tgctcctgat ctgattatta atgagcagag aatgactcta 2040 ccctgcatgt acgaccaatg taaacacatg ctgtatgttt cctctgagtt acacaggctt 2100 caggtatctt atgaagagta tctctgtatg aaaaccttac tgcttctctc ttcagttcct 2160 aaggacggtc tgaagagcca agagctattt gatgaaatta gaatgaccta catcaaagag 2220 ctaggaaaag ccattgtcaa gagggaagga aactccagcc agaactggca gcggttttat 2280 caactgacaa aactcttgga ttctatgcat gaagtggttg aaaatctcct taactattgc 2340 ttccaaacat ttttggataa gaccatgagt attgaattcc ccgagatgtt agctgaaatc 2400 atcaccaatc agataccaaa atattcaaat ggaaatatca aaaaacttct gtttcatcaa 2460 aagtgactgc cttaataaga atggttgcct taaagaaagt cgaattaata gcttttattg 2520 tataaactat cagtttgtcc tgtagaggtt ttgttgtttt attttttatt gttttcatct 2580 gttgttttgt tttaaatacg cactacatgt ggtttataga gggccaagac ttggcaacag 2640 aagcagttga gtcgtcatca cttttcagtg atgggagagt agatggtgaa atttattagt 2700 taatatatcc cagaaattag aaaccttaat atgtggacgt aatctccaca gtcaaagaag 2760 gatggcacct aaaccaccag tgcccaaagt ctgtgtgatg aactttctct tcatactttt 2820 tttcacagtt ggctggatga aattttctag actttctgtt ggtgtatccc ccccctgtat 2880 agttaggata gcatttttga tttatgcatg gaaacctgaa aaaaagttta caagtgtata 2940 tcagaaaagg gaagttgtgc cttttatagc tattactgtc tggttttaac aatttccttt 3000 atatttagtg aactacgctt gctcattttt tcttacataa ttttttattc aagttattgt 3060 acagctgttt aagatgggca gctagttcgt agctttccca aataaactct aaacattaat 3120 caatcatctg tgtgaaaatg ggttggtgct tctaacctga tggcacttag ctatcagaag 3180 accacaaaaa ttgactcaaa tctccagtat tcttgtcaaa aaaaaaaaaa aaaaagctca 3240 tattttgtat atatctgctt cagtggagaa ttatataggt tgtgcaaatt aacagtccta 3300 actggtatag agcacctagt ccagtgacct gctgggtaaa ctgtggatga tggttgcaaa 3360 agactaattt aaaaaataac taccaagagg ccctgtctgt acctaacgcc ctatttttgc 3420 aatggctata tggcaagaaa gctggtaaac tatttgtctt tcaggacctt ttgaagtagt 3480 ttgtataact tcttaaaagt tgtgattcca gataaccagc tgtaacacag ctgagagact 3540 tttaatcaga caaagtaatt cctctcacta aactttaccc aaaaactaaa tctctaatat 3600 ggcaaaaatg gctagacacc cattttcaca ttcccatctg tcaccaattg gttaatcttt 3660 cctgatggta caggaaagct cagctactga tttttgtgat ttagaactgt atgtcagaca 3720 tccatgtttg taaaactaca catccctaat gtgtgccata gagtttaaca caagtcctgt 3780 gaatttcttc actgttgaaa attattttaa acaaaataga agctgtagta gccctttctg 3840 tgtgcacctt accaactttc tgtaaactca aaacttaaca tatttactaa gccacaagaa 3900 atttgatttc tattcaaggt ggccaaatta tttgtgtaat agaaaactga aaatctaata 3960 ttaaaaatat ggaacttcta atatattttt atatttagtt atagtttcag atatatatca 4020 tattggtatt cactaatctg ggaagggaag ggctactgca gctttacatg caatttatta 4080 aaatgattgt aaaatagctt gtatagtgta aaataagaat gatttttaga tgagattgtt 4140 ttatcatgac atgttatata ttttttgtag gggtcaaaga aatgctgatg gataacctat 4200 atgatttata gtttgtacat gcattcatac aggcagcgat ggtctcagaa accaaacagt 4260 ttgctctagg ggaagaggga gatggagact ggtcctgtgt gcagtgaagg ttgctgaggc 4320 tctgacccag tgagattaca gaggaagtta tcctctgcct cccattctga ccacccttct 4380 cattccaaca gtgagtctgt cagcgcaggt ttagtttact caatctcccc ttgcactaaa 4440 gtatgtaaag tatgtaaaca ggagacagga aggtggtgct tacatcctta aaggcaccat 4500 ctaatagcgg gttactttca catacagccc tcccccagca gttgaatgac aacagaagct 4560 tcagaagttt ggcaatagtt tgcatagagg taccagcaat atgtaaatag tgcagaatct 4620 cataggttgc caataataca ctaattcctt tctatcctac aacaagagtt tatttccaaa 4680 taaaatgagg acatgttttt gttttctttg aatgcttttt gaatgttatt tgttattttc 4740 agtattttgg agaaattatt taataaaaaa acaatcattt gctttttg 4788 <210> 100 <211> 2038 <212> DNA <213> HUMAN <400> 100 ggctataagc gcacggcctc ggcgaccctc tccgacccgg ccgccgccgc catgcagccc 60 tccagccttc tgccgctcgc cctctgcctg ctggctgcac ccgcctccgc gctcgtcagg 120 atcccgctgc acaagttcac gtccatccgc cggaccatgt cggaggttgg gggctctgtg 180 gaggacctga ttgccaaagg ccccgtctca aagtactccc aggcggtgcc agccgtgacc 240 gaggggccca ttcccgaggt gctcaagaac tacatggacg cccagtacta cggggagatt 300 ggcatcggga cgccccccca gtgcttcaca gtcgtcttcg acacgggctc ctccaacctg 360 tgggtcccct ccatccactg caaactgctg gacatcgctt gctggatcca ccacaagtac 420 aacagcgaca agtccagcac ctacgtgaag aatggtacct cgtttgacat ccactatggc 480 tcgggcagcc tctccgggta cctgagccag gacactgtgt cggtgccctg ccagtcagcg 540 tcgtcagcct ctgccctggg cggtgtcaaa gtggagaggc aggtctttgg ggaggccacc 600 aagcagccag gcatcacctt catcgcagcc aagttcgatg gcatcctggg catggcctac 660 ccccgcatct ccgtcaacaa cgtgctgccc gtcttcgaca acctgatgca gcagaagctg 720 gtggaccaga acatcttctc cttctacctg agcagggacc cagatgcgca gcctgggggt 780 gagctgatgc tgggtggcac agactccaag tattacaagg gttctctgtc ctacctgaat 840 gtcacccgca aggcctactg gcaggtccac ctggaccagg tggaggtggc cagcgggctg 900 accctgtgca aggagggctg tgaggccatt gtggacacag gcacttccct catggtgggc 960 ccggtggatg aggtgcgcga gctgcagaag gccatcgggg ccgtgccgct gattcagggc 1020 gagtacatga tcccctgtga gaaggtgtcc accctgcccg cgatcacact gaagctggga 1080 ggcaaaggct acaagctgtc cccagaggac tacacgctca aggtgtcgca ggccgggaag 1140 accctctgcc tgagcggctt catgggcatg gacatcccgc cacccagcgg gccactctgg 1200 atcctgggcg acgtcttcat cggccgctac tacactgtgt ttgaccgtga caacaacagg 1260 gtgggcttcg ccgaggctgc ccgcctctag ttcccaaggc gtccgcgcgc cagcacagaa 1320 acagaggaga gtcccagagc aggaggcccc tggcccagcg gcccctccca cacacaccca 1380 cacactcgcc cgcccactgt cctgggcgcc ctggaagccg gcggcccaag cccgacttgc 1440 tgttttgttc tgtggttttc ccctccctgg gttcagaaat gctgcctgcc tgtctgtctc 1500 tccatctgtt tggtgggggt agagctgatc cagagcacag atctgtttcg tgcattggaa 1560 gaccccaccc aagcttggca gccgagctcg tgtatcctgg ggctcccttc atctccaggg 1620 agtcccctcc ccggccctac cagcgcccgc tgggctgagc ccctacccca caccaggccg 1680 tcctcccggg ccctcccttg gaaacctgcc ctgcctgagg gcccctctgc ccagcttggg 1740 cccagctggg ctctgccacc ctacctgttc agtgtcccgg gcccgttgag gatgaggccg 1800 ctagaggcct gaggatgagc tggaaggagt gagaggggac aaaacccacc ttgttggagc 1860 ctgcagggtg gtgctgggac tgagccagtc ccaggggcat gtattggcct ggaggtgggg 1920 ttgggattgg gggctggtgc cagccttcct ctgcagctga cctctgttgt cctccccttg 1980 ggcggctgag agccccagct gacatggaaa tacagttgtt ggcctccggc ctcccctc 2038 <210> 101 <211> 1959 <212> DNA <213> HUMAN <400> 101 ttggagtcaa cactttcgat tccaccttgg gaagccccca aggagcataa gtacaaagct 60 gaagagcaca cagtcgttct cactgtcacc ggggagccct gccacttccc cttccagtac 120 caccggcagc tgtaccacaa atgtacccac aagggccggc caggccctca gccctggtgt 180 gctaccaccc ccaactttga tcaggaccag cgatggggat actgtttgga gcccaagaaa 240 gtgaaagacc actgcagcaa acacagcccc tgccagaaag gagggacctg tgtgaacatg 300 ccaagcggcc cccactgtct ctgtccacaa cacctcactg gaaaccactg ccagaaagag 360 aagtgctttg agcctcagct tctccggttt ttccacaaga atgagatatg gtatagaact 420 gagcaagcag ctgtggccag atgccagtgc aagggtcctg atgcccactg ccagcggctg 480 gccagccagg cctgccgcac caacccgtgc ctccatgggg gtcgctgcct agaggtggag 540 ggccaccgcc tgtgccactg cccggtgggc tacaccggac ccttctgcga cgtggacacc 600 aaggcaagct gctatgatgg ccgcgggctc agctaccgcg gcctggccag gaccacgctc 660 tcgggtgcgc cctgtcagcc gtgggcctcg gaggccacct accggaacgt gactgccgag 720 caagcgcgga actggggact gggcggccac gccttctgcc ggaacccgga caacgacatc 780 cgcccgtggt gcttcgtgct gaaccgcgac cggctgagct gggagtactg cgacctggca 840 cagtgccaga ccccaaccca ggcggcgcct ccgaccccgg tgtcccctag gcttcatgtc 900 ccactcatgc ccgcgcagcc ggcaccgccg aagcctcagc ccacgacccg gaccccgtct 960 cagtcccaga ccccgggagc cttgccggcg aagcgggagc agccgccttc cctgaccagg 1020 aacggcccac tgagctgcgg gcagcggctc cgcaagagtc tgtcttcgat gacccgcgtc 1080 gttggcgggc tggtggcgct acgcggggcg cacccctaca tcgccgcgct gtactggggc 1140 cacagtttct gcgccggcag cctcatcgcc ccctgctggg tgctgacggc cgctcactgc 1200 ctgcaggacc ggcccgcacc cgaggatctg acggtggtgc tcggccagga acgccgtaac 1260 cacagctgtg agccgtgcca gacgttggcc gtgcgctcct accgcttgca cgaggccttc 1320 tcgcccgtca gctaccagca cgacctggct ctgttgcgcc ttcaggagga tgcggacggc 1380 agctgcgcgc tcctgtcgcc ttacgttcag ccggtgtgcc tgccaagcgg cgccgcgcga 1440 ccctccgaga ccacgctctg ccaggtggcc ggctggggcc accagttcga gggggcggag 1500 gaatatgcca gcttcctgca ggaggcgcag gtaccgttcc tctccctgga gcgctgctca 1560 gccccggacg tgcacggatc ctccatcctc cccggcatgc tctgcgcagg gttcctcgag 1620 ggcggcaccg atgcgtgcca gggtgattcc ggaggcccgc tggtgtgtga ggaccaagct 1680 gcagagcgcc ggctcaccct gcaaggcatc atcagctggg gatcgggctg tggtgaccgc 1740 aacaagccag gcgtctacac cgatgtggcc tactacctgg cctggatccg ggagcacacc 1800 gtttcctgat tgctcaggga ctcatctttc cctccttggt gattccgcag tgagagagtg 1860 gctggggcat ggaaggcaag attgtgtccc attcccccag tgcggccagc tccgcgccag 1920 gatggcgcag gaactcaata aagtgctttg aaaatgctg 1959 <210> 102 <211> 2087 <212> DNA <213> HUMAN <400> 102 ttattaagaa ttgcagcaag taagccaaca aggtcttttc aggatgattt tcttatatca 60 agtggtacat ttcattttat ttacttcagt ttctggtgaa tgtgtgactc agttgttgaa 120 ggacacctgc tttgaaggag gggacattac tacggtcttc acaccaagcg ccaagtactg 180 ccaggtagtc tgcacttacc acccaagatg tttactcttc actttcacgg cggaatcacc 240 atctgaggat cccacccgat ggtttacttg tgtcctgaaa gacagtgtta cagaaacact 300 gccaagagtg aataggacag cagcgatttc tgggtattct ttcaagcaat gctcacacca 360 aataagcgct tgcaacaaag acatttatgt ggacctagac atgaagggca taaactataa 420 cagctcagtt gccaagagtg ctcaagaatg ccaagaaaga tgcacggatg acgtccactg 480 ccactttttc acgtacgcca caaggcagtt tcccagcctg gagcatcgta acatttgtct 540 actgaagcac acccaaacag ggacaccaac cagaataacg aagctcgata aagtggtgtc 600 tggattttca ctgaaatcct gtgcactttc taatctggct tgtattaggg acattttccc 660 taatacggtg tttgcagaca gcaacatcga cagtgtcatg gctcccgatg cttttgtctg 720 tggccgaatc tgcactcatc atcccggttg cttgtttttt accttctttt cccaggaatg 780 gcccaaagaa tctcaaagaa atctttgtct ccttaaaaca tctgagagtg gattgcccag 840 tacacgcatt aaaaagagca aagctctttc tggtttcagt ctacaaagct gcaggcacag 900 catcccagtg ttctgccatt cttcatttta ccatgacact gatttcttgg gagaagaact 960 ggatattgtt gctgcaaaaa gtcacgaggc ctgccagaaa ctgtgcacca atgccgtccg 1020 ctgccagttt tttacctata ccccagccca agcatcctgc aacgaaggga agggcaagtg 1080 ttacttaaag ctttcttcaa acggatctcc aactaaaata cttcacggga gaggaggcat 1140 ctctggatac acattaaggt tgtgtaaaat ggataatgag tgtaccacca aaatcaagcc 1200 caggatcgtt ggaggaactg cgtctgttcg tggtgagtgg ccgtggcagg tgaccctgca 1260 cacaacctca cccactcaga gacacctgtg tggaggctcc atcattggaa accagtggat 1320 attaacagcc gctcactgtt tctatggggt agagtcacct aagattttgc gtgtctacag 1380 tggcatttta aatcaatctg aaataaaaga ggacacatct ttctttgggg ttcaagaaat 1440 aataatccat gatcagtata aaatggcaga aagcgggtat gatattgcct tgttgaaact 1500 ggaaaccaca gtgaattaca cagattctca acgacccata tgcctgcctt ccaaaggaga 1560 tagaaatgta atatacactg attgctgggt gactggatgg gggtacagaa aactaagaga 1620 caaaatacaa aatactctcc agaaagccaa gataccctta gtgaccaacg aagagtgcca 1680 gaagagatac agaggacata aaataaccca taagatgatc tgtgccggct acagggaagg 1740 agggaaggac gcttgcaagg gagattcggg aggccctctg tcctgcaaac acaatgaggt 1800 ctggcatctg gtaggcatca cgagctgggg cgaaggctgt gctcaaaggg agcggccagg 1860 tgtttacacc aacgtggtcg agtacgtgga ctggattctg gagaaaactc aagcagtgtg 1920 aatgggttcc caggggccat tggagtccct gaaggaccca ggatttgctg ggagagggtg 1980 ttgagttcac tgtgccagca tgcttcctcc acagtaacac gctgaagggg cttggtgttt 2040 gtaagaaaat gctagaagaa aacaaactgt cacaagttgt tatgtcc 2087 <210> 103 <211> 2002 <212> DNA <213> HUMAN <400> 103 aattccgcgg caaccgctcc ggcaacgcca accgctccgc tgcgcgcagg ctgggctgca 60 ggctctcggc tgcagcgctg ggctggtgtg cagtggtgcg accacggctc acggcagcct 120 cagccaccca gatgtaagcg atctggttcc cacctcagcc ttccgagtag tggatctagg 180 atctggcttc caacatgtgg cagctctggg cctccctctg ctgcctgctg gtgttggcca 240 atgcccggag caggccctct ttccatcccg tgtcggatga gctggtcaac tatgtcaaca 300 aacggaatac cacgtggcag gccgggcaca acttctacaa cgtggacatg agctacttga 360 agaggctatg tggtaccttc ctgggtgggc ccaagccacc ccagagagtt atgtttaccg 420 aggacctgaa gctgcctgca agcttcgatg cacgggaaca atggccacag tgtcccacca 480 tcaaagagat cagagaccag ggctcctgtg gctcctgctg ggccttcggg gctgtggaag 540 ccatctctga ccgcatctgc atccacacca atgcgcacgt cagcgtggag gtgtcggcgg 600 aggacctgct cacctgctgt ggcagcatgt gtggggacgg ctgtaatggt ggctatcctg 660 ctgaagcttg gaacttctgg acaagaaaag gcctggtttc tggtggcctc tatgaatccc 720 atgtagggtg cagaccgtac tccatccctc cctgtgagca ccacgtcaac ggctcccggc 780 ccccatgcac gggggaggga gataccccca agtgtagcaa gatctgtgag cctggctaca 840 gcccgaccta caaacaggac aagcactacg gatacaattc ctacagcgtc tccaatagcg 900 agaaggacat catggccgag atctacaaaa acggccccgt ggagggagct ttctctgtgt 960 attcggactt cctgctctac aagtcaggag tgtaccaaca cgtcaccgga gagatgatgg 1020 gtggccatgc catccgcatc ctgggctggg gagtggagaa tggcacaccc tactggctgg 1080 ttgccaactc ctggaacact gactggggtg acaatggctt ctttaaaata ctcagaggac 1140 aggatcactg cggaatcgaa tcagaagtgg tggctggaat tccacgcacc gatcagtact 1200 gggaaaagat ctaatctgcc gtgggcctgt cgtgccagtc ctgggggcga gatcggggta 1260 gaaagtcatt ttattcttta agttcacgta agatacaagt ttcaggcagg gtctgaagga 1320 ctggattggc caaagtcctc caaggagacc aagtcctggc tacatcccag cctgtggtta 1380 cagtgcagac aggccatgtg agccaccgct gccagcacag agcgtccttc cccctgtaga 1440 ctagtgccgt gggagtacct gctgcccagc tgctgtggcc ccctccgtga tccatccatc 1500 tccagggagc aagacagaga cgcaggatgg aaagcggagt tcctaacagg atgaaagttc 1560 ccccatcagt tcccccagta cctccaagca agtagctttc cacatttgtc acagaaatca 1620 gaggagagat ggtgttggga gccctttgga gaacgccagt ctccaggtcc ccctgcatct 1680 atcgagtttg caatgtcaca acctctctga tcttgtgctc agcatgattc tttaatagaa 1740 gttttatttt tcgtgcactc tgctaatcat gtgggtgagc cagtggaaca gcgggagcct 1800 gtgctggttt gcagattgcc tcctaatgac gcggctcaaa aggaaaccaa gtggtcagga 1860 gttgtttctg acccactgat ctctactacc acaaggaaaa tagtttagga gaaaccagct 1920 tttactgttt ttgaaaaatt acagcttcac cctgtcaagt taacaaggaa tgcctgtgcc 1980 aataaaaggt ttctccaact tg 2002 <210> 104 <211> 780 <212> DNA <213> HUMAN <400> 104 ggatataggc gcccccacac ccgggcccgg ctaagcgccg ccgccgctcc tcgcctcctt 60 gctgcacgat ggcctcgctc cgggtggagc gcgccggcgg cccgcgtctc cctaggaccc 120 gagtcgggcg gccggcagcc gtccgcctcc tccttctgct gggcgctgtc ctgaatcccc 180 acgaggccct ggctcagcct cttcccacca caggcacacc agggtcagaa ggggggacgg 240 tgaagaacta tgagacagct gtccaatttt gctggaatca ttataaggat caaatggatc 300 ctatcgaaaa ggattggtgc gactgggcca tgattagcag gccttatagc accctgcgag 360 attgcctgga gcactttgca gagttgtttg acctgggctt ccccaatccc ttggcagaga 420 ggatcatctt tgagactcac cagatccact ttgccaactg ctccctggtg cagcccacct 480 tctctgaccc cccagaggat gtactcctgg ccatgatcat agcccccatc tgcctcatcc 540 ccttcctcat cactcttgta gtatggagga gtaaagacag tgaggcccag gcctaggggg 600 cacgagcttc tcaacaacca tgttactcca cttccccacc cccaccaggc ctccctcctc 660 ccctcctact cccttttctc actctcatcc ccaccacaga tccctggatt gctgggaatg 720 gaagccaggg ttgggcatgg cacaagttct gtaatcttca aaataaaact ttttttttga 780 <210> 105 <211> 1312 <212> DNA <213> HUMAN <400> 105 gagcgtgacc cagctgcggc cggccagcca tggagactgg agcgctgcgg cgcccgcaac 60 ttctcccgtt gctgctgctg ctctgcggtg ggtgtcccag agcaggcggc tgcaacgaga 120 caggcatgtt ggagaggctg cccctgtgtg ggaaggcttt cgcagacatg atgggcaagg 180 tggacgtctg gaagtggtgc aacctgtccg agttcatcgt gtactatgag agtttcacca 240 actgcaccga gatggaggcc aatgtcgtgg gctgctactg gcccaacccc ctggcccagg 300 gcttcatcac cggcatccac aggcagttct tctccaactg caccgtggac agggtccact 360 tggaggaccc cccagacgag gttctcatcc cgctgatcgt tatacccgtc gttctgactg 420 tcgccatggc tggcctggtg gtgtggcgca gcaaacgcac cgacacgctg ctgtgagggt 480 cccggtgaga tggagtgggt cacacctggc aagctggaag aaagttccct ggggatggga 540 gatcgggtgg gtgctgccaa tctccagcta ctgtggccac accccacctg gtcatgggca 600 gacccctccc ttcctgggct gacctgctcc ctcgaggcca gcctgctccc tggctgaggc 660 tcaggctatc cgcccaagct ctttgctcat tctagggcca gtggaggaaa atgtgataag 720 gccagagctt gtgtgctggg caagaaatca cctgctgcat cctgtgctcc gcaggctggg 780 ccggaagcct ctgcctgcag gtttctatgc tgtttcttag cacagaatcc agcctagcct 840 tagccgcagt ctaggccctg cttggactag gactccttgc ttgaccccat ctctggttcc 900 tgccctggct cctgcaccag ccccagctcc tgcctacatc caggcagaaa tataggcagg 960 ggctcttgga agacgttccg tgctgtgacc tccgagccct cctggtggga agacagctgg 1020 aaaggctggg aggagaaggg aggggctggg ggttcccagg agccatgcgt ggcctgcaga 1080 gtccattcca tcatgatgct gtgcccgcta tgggctgtgt ccatgaccag aggctggagt 1140 gggggtgtgt tatagcccct caccgggact tgctgtgcgg atggggcctg ggcctccttc 1200 ctacaggggc tcctctgtgg gtgaggggcc ctctggaatg gcatcccatg agcttgtggc 1260 ctctatctgc taccatctgt gttttatctg agtaaagtta ccttacttct gg 1312 <210> 106 <211> 1938 <212> DNA <213> HUMAN <400> 106 attccggttg ttgcaccatg gcgtccatgg ggaccctcgc cttcgatgaa tatgggcgcc 60 ctttcctcat catcaaggat caggaccgca agtcccgtct tatgggactt gaggccctca 120 agtctcatat aatggcagca aaggctgtag caaatacaat gagaacatca cttggaccaa 180 atgggcttga taagatgatg gtggataagg atggagatgt gactgtaact aatgatgggg 240 ccaccatctt aagcatgatg gatgttgatc atcagattgc caagctgatg gtggaactgt 300 ccaagtctca ggatgatgaa attggagatg gaaccacagg agtggttgtc ctggctggtg 360 ccttgttaga agaagcggag caattgctag accgaggcat tcacccaatc agaatagccg 420 atggctatga gcaggctgct cgtgttgcta ttgaacacct ggacaagatc agcgatagcg 480 tccttgttga cataaaggac accgaacccc tgattcagac agcaaaaacc acgctgggct 540 ccaaagtggt caacagttgt caccgacaga tggctgagat tgctgtgaat gccgtcctca 600 ctgtagcaga tatggagcgg agagacgttg actttgagct tatcaaagta gaaggcaaag 660 tgggcggcag gctggaggac actaaactga ttaagggcgt gattgtggac aaggatttca 720 gtcacccaca gatgccaaaa aaagtggaag atgcgaagat tgcaattctc acatgtccat 780 ttgaaccacc caaaccaaaa acaaagcata agctggatgt gacctctgtc gaagattata 840 aagcccttca gaaatacgaa aaggagaaat ttgaagagat gattcaacaa attaaagaga 900 ctggtgctaa cctagcaatt tgtcagtggg gctttgatga tgaagcaaat cacttacttc 960 ttcagaacaa cttgcctgcg gttcgctggg taggaggacc tgaaattgag ctgattgcca 1020 tcgcaacagg agggcggatc gtccccaggt tctcagagct cacagccgag aagctgggct 1080 ttgctggtct tgtacaggag atctcatttg ggacaactaa ggataaaatg ctggtcatcg 1140 agcagtgtaa gaactccaga gctgtaacca tttttattag aggaggaaat aagatgatca 1200 ttgaggaggc gaaacgatcc cttcacgatg ctttgtgtgt catccggaac ctcatccgcg 1260 ataatcgtgt ggtgtatgga ggaggggctg ctgagatatc ctgtgccctg gcagttagcc 1320 aagaggcgga taagtgcccc accttagaac agtatgccat gagagcgttt gccgacgcac 1380 tggaggtcat ccccatggcc ctctctgaaa acagtggcat gaatcccatc cagactatga 1440 ccgaagtccg agccagacag gtgaaggaga tgaaccctgc tcttggcatc gactgtttgc 1500 acaaggggac aaatgatatg aagcaacagc atgtcataga aaccttgatt ggcaaaaagc 1560 aacagatatc tcttgcaaca caaatggtta gaatgatttt gaagattgat gacattcgta 1620 agcctggaga atctgaagaa tgaagacatt gagaaaacta tgtagcaaga tccacttctg 1680 tgattaagta aatggatgtc tcgtgatgca tctacagtta tttattgtta catccttttc 1740 cagacactgt agatgctata ataaaaatag ctgtttggta accatagttt cacttgttca 1800 aagctgtgta atcgtggggg taccatctca actgcttttg tattcattgt attaaaagaa 1860 tctgtttaaa caacctttat cttctcttcg ggtttaagaa acgtttattg taacagtaat 1920 taaatgctgc cttaattg 1938 <210> 107 <211> 3002 <212> DNA <213> HUMAN <400> 107 gccattctct cacatcccgt gcggtcagga agcccttcct gaactctgac ttcagttctt 60 gctgcggttt ctgcccattt ttttcatatc ctctgacagc tgcgaggtca tctctgctct 120 ggcttttctc caagcagaac aagtgggggc tctggaaagg ttaagggacc tcagtggcca 180 ccattatact ttgcatcttt cctgagaagt gagagttgaa agggaagcag gaaggcccat 240 ggtcagattg aaggaaggac tttttagttt cttttttttt tttttgaaat ggagtctcgc 300 tctgtcattc aggctggagt gcagtggtgc gatctcagct cactgcagcc tccacttcct 360 gggttcacat gattctcctg cctcagcctc ccaagtagct gagactacag gcacatgcca 420 ctacacccag ctaacttttg tatttttagt agagacgggg tttcaccatg ttggccaggc 480 tggtctcaaa ctgctaacat caagtgatct gctcccctca gcctcccaaa gtgctgggat 540 taccggtatg aaccaccaca acctgccagg aatttttagt ttttagcttt tgcaggagac 600 ttcaaggaaa ggagacattc ctctgtccag gaaacgggta aggggaccat ttctgcattg 660 ctggtttccc ctcttggcag ggtgggcatg aggcatcact gttcctgctc cctcactcct 720 gctcctcatg ctcagcctgc cagctcggcc tcaactttgt gtgtctaaag tggaactgaa 780 tagtagctgt gagaagatag gaaagaggta gtgccaatct ccttgcccag atcataaatc 840 cagactcagc agggtaacca catgggcaag cacaaggtag gtgcttgggg aaaggggaag 900 taattggcat tctgtgtgat accaaggaga ccatttggat tttggcttct accaaagaga 960 atggagaatt ggttgaccta aatggaacca gtccctttaa gtaaggggag gaaagggggt 1020 gctggaagat ggccctcttc ccaccaccta gatcatagct tgaactgaag ccaaggacag 1080 agtgctgccc ccttcggcat ttactgatgt gccctcttta aatcatgatg ttatctaacc 1140 caaacccaga cccaggacct agtcacagct ccaacctaca cttcctatta atcttaaaac 1200 aaagcgaaac aaacacaaaa agatatcagc attgtagcct ccaatctgag cccatttccc 1260 ttctctggct accatacctc cttctcctat atgataccat tcactacttt gttcaattat 1320 ccagtctaga cctgcatctt gaggccacac ccagccttct cactccccac acccctcttt 1380 cctctctcac tgctccttcc tggtctcttc tcatctggcc ccacctctaa ggagtcctcc 1440 tgccttctgg gttgccctgg aaaacagact atcccccctc ctagtgaagg gagtgggtag 1500 gggtttcagc cccaccctca ggaagatgcg tcttccctgt cctctgctct gtggtacttc 1560 ctctctggct gatttagcaa acagcaccta gacctggggc caggcctttg gcagtgggac 1620 agatccaggg ataggctaca ccaccctgcc ctgaccctgg gattggcatc agcttccaac 1680 cagttcctgc caaagcttgt aagtcctccc gacggccatg aacactacat cttctgcagc 1740 acccccctca ctaggtgtag agttcatctc tctgctggct atcatcctgc tgtcagtggc 1800 gctggctgtg gggcttcccg gcaacagctt tgtggtgtgg agtatcctga aaaggatgca 1860 gaagcgctct gtcactgccc tgatggtgct gaacctggcc ctggccgacc tggccgtatt 1920 gctcactgct ccctttttcc ttcacttcct ggcccaaggc acctggagtt ttggactggc 1980 tggttgccgc ctgtgtcact atgtctgcgg agtcagcatg tacgccagcg tcctgcttat 2040 cacggccatg agtctagacc gctcactggc ggtggcccgc ccctttgtgt cccagaagct 2100 acgcaccaag gcgatggccc ggcgggtgct ggcaggcatc tgggtgttgt cctttctgct 2160 ggccacaccc gtcctcgcgt accgcacagt agtgccctgg aaaacgaaca tgagcctgtg 2220 cttcccgcgg taccccagcg aagggcaccg ggccttccat ctaatcttcg aggctgtcac 2280 gggcttcctg ctgcccttcc tggctgtggt ggccagctac tcggacatag ggcgtcggct 2340 acaggcccgg cgcttccgcc gcagccgccg caccggccgc ctggtggtgc tcatcatcct 2400 gaccttcgcc gccttctggc tgccctacca cgtggtgaac ctggctgagg cgggccgcgc 2460 gctggccggc caggccgccg ggttagggct cgtggggaag cggctgagcc tggcccgcaa 2520 cgtgctcatc gcactcgcct tcctgagcag cagcgtgaac cccgtgctgt acgcgtgcgc 2580 cggcggcggc ctgctgcgct cggcgggcgt gggcttcgtc gccaagctgc tggagggcac 2640 gggttccgag gcgtccagca cgcgccgcgg gggcagcctg ggccagaccg ctaggagcgg 2700 ccccgccgct ctggagcccg gcccttccga gagcctcact gcctccagcc ctctcaagtt 2760 aaacgaactg aactaggcct ggtggaagga ggcgcacttt cctcctggca gaatgctagc 2820 tctgagccag ttcagtacct ggaggaggag caggggcgtg gagggcgtgg agggcgtggg 2880 agcgtgggag gcgggagtgg agtggaagaa gagggagaga tggagcaaag tgagggccga 2940 gtgagagcgt gctccagcct ggctcccaca ggcagcttta accattaaaa ctgaagtctg 3000 aa 3002 <210> 108 <211> 1854 <212> DNA <213> HUMAN <400> 108 ggcccaggct gaagctcagg gccctgtctg ctctgtggac tcaacagttt gtggcaagac 60 aagctcagaa ctgagaagct gtcaccacag ttctggaggc tgggaagttc aagatcaaag 120 tgccagcaga ttcagtgtca tgtgaggacg tgcttcctgc ttcatagata agagtagctt 180 ggagctcggc ggcacaacca gcaccatctg gtcgcgatgg tggacacgga aagcccactc 240 tgccccctct ccccactcga ggccggcgat ctagagagcc cgttatctga agagttcctg 300 caagaaatgg gaaacatcca agagatttcg caatccatcg gcgaggatag ttctggaagc 360 tttggcttta cggaatacca gtatttagga agctgtcctg gctcagatgg ctcggtcatc 420 acggacacgc tttcaccagc ttcgagcccc tcctcggtga cttatcctgt ggtccccggc 480 agcgtggacg agtctcccag tggagcattg aacatcgaat gtagaatctg cggggacaag 540 gcctcaggct atcattacgg agtccacgcg tgtgaaggct gcaagggctt ctttcggcga 600 acgattcgac tcaagctggt gtatgacaag tgcgaccgca gctgcaagat ccagaaaaag 660 aacagaaaca aatgccagta ttgtcgattt cacaagtgcc tttctgtcgg gatgtcacac 720 aacgcgattc gttttggacg aatgccaaga tctgagaaag caaaactgaa agcagaaatt 780 cttacctgtg aacatgacat agaagattct gaaactgcag atctcaaatc tctggccaag 840 agaatctacg aggcctactt gaagaacttc aacatgaaca aggtcaaagc ccgggtcatc 900 ctctcaggaa aggccagtaa caatccacct tttgtcatac atgatatgga gacactgtgt 960 atggctgaga agacgctggt ggccaagctg gtggccaatg gcatccagaa caaggaggtg 1020 gaggtccgca tctttcactg ctgccagtgc acgtcagtgg agaccgtcac ggagctcacg 1080 gaattcgcca aggccatccc agcgttcgca aacttggacc tgaacgatca agtgacattg 1140 ctaaaatacg gagtttatga ggccatattc gccatgctgt cttctgtgat gaacaaagac 1200 gggatgctgg tagcgtatgg aaatgggttt ataactcgtg aattcctaaa aagcctaagg 1260 aaaccgttct gtgatatcat ggaacccaag tttgattttg ccatgaagtt caatgcactg 1320 gaactggatg acagtgatat ctcccttttt gtggctgcta tcatttgctg tggagatcgt 1380 cctggccttc taaacgtagg acacattgaa aaaatgcagg agggtattgt acatgtgctc 1440 agactccacc tgcagagcaa ccacccggac gatatctttc tcttcccaaa acttcttcaa 1500 aaaatggcag acctccggca gctggtgacg gagcatgcgc agctggtgca gatcatcaag 1560 aagacggagt cggatgctgc gctgcacccg ctactgcagg agatctacag ggacatgtac 1620 tgagttcctt cagatcagcc acaccttttc caggagttct gaagctgaca gcactacaaa 1680 ggagacgggg gagcagcacg attttgcaca aatatccacc actttaacct tagagcttgg 1740 acagtctgag ctgtaggtaa ccggcatatt attccatatc tttgttttaa ccagtacttc 1800 taagagcata gaactcaaat gctgggggag gtggctaatc tcaggactgg gaag 1854 <210> 109 <211> 1643 <212> DNA <213> HUMAN <400> 109 ggaattccct gatatacacc tggaccacca ccaatggata tacaaatggc aaacaatttt 60 actccgccct ctgcaactcc tcagggaaat gactgtgacc tctatgcaca tcacagcacg 120 gccaggatag taatgcctct gcattacagc ctcgtcttca tcattgggct cgtgggaaac 180 ttactagcct tggtcgtcat tgttcaaaac aggaaaaaaa tcaactctac caccctctat 240 tcaacaaatt tggtgatttc tgatatactt tttaccacgg ctttgcctac acgaatagcc 300 tactatgcaa tgggctttga ctggagaatc ggagatgcct tgtgtaggat aactgcgcta 360 gtgttttaca tcaacacata tgcaggtgtg aactttatga cctgcctgag tattgaccgc 420 ttcattgctg tggtgcaccc tctacgctac aacaagataa aaaggattga acatgcaaaa 480 ggcgtgtgca tatttgtctg gattctagta tttgctcaga cactcccact cctcatcaac 540 cctatgtcaa agcaggaggc tgaaaggatt acatgcatgg agtatccaaa ctttgaagaa 600 actaaatctc ttccctggat tctgcttggg gcatgtttca taggatatgt acttccactt 660 ataatcattc tcatctgcta ttctcagatc tgctgcaaac tcttcagaac tgccaaacaa 720 aacccactca ctgagaaatc tggtgtaaac aaaaaggctc tcaacacaat tattcttatt 780 attgttgtgt ttgttctctg tttcacacct taccatgttg caattattca acatatgatt 840 aagaagcttc gtttctctaa tttcctggaa tgtagccaaa gacattcgtt ccagatttct 900 ctgcacttta cagtatgcct gatgaacttc aattgctgca tggacccttt tatctacttc 960 tttgcatgta aagggtataa gagaaaggtt atgaggatgc tgaaacggca agtcagtgta 1020 tcgatttcta gtgctgtgaa gtcagcccct gaagaaaatt cacgtgaaat gacagaaacg 1080 cagatgatga tacattccaa gtcttcaaat ggaaagtgaa atggattgta ttttggttta 1140 tagtgacgta aactgtatga caaactttgc aggacttccc ttataaagca aaataattgt 1200 tcagcttcca attagtattc ttttatattt ctttcattgg gcgctttccc atctccaact 1260 cggaagtaag cccaagagaa caacataaag caaacaacat aaagcacaat aaaaatgcaa 1320 ataaatattt tcatttttat ttgtaaacga atacaccaaa aggaggcgct cttaataact 1380 cccaatgtaa aaagttttgt tttaataaaa aattaattat tattcttgcc aacaaatggc 1440 tagaaaggac tgaatagatt atatattgcc agatgttaat actgtaacat actttttaaa 1500 taacatattt cttaaatcca aatttctctc aatgttagat ttaattccct caataacacc 1560 aatgttttgt tttgtttcgt tctgggtcat aaaactttgt taaggaactc ttttggaata 1620 aagagcagga tgctgcggaa ttc 1643 <210> 110 <211> 1812 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(1812) <223> N=any base <400> 110 cgtcgctgcc ggtctcccgg agaganctct ggagtttggg cggcccgggc ggccactagg 60 tactctgata ttccgtacta aacacgtctg caagtcaaga tgtcgcaccc gtccccccaa 120 gccaagccct ccaaccccag taaccctcga gtcttctttg acgtggacat cggaggggag 180 cgagttggtc gaattgtctt agaattgttt gcagatatcg tacccaaaac tgcggaaaat 240 tttcgtgcac tgtgtacagg agaaaaaggc attggacaca cgactgggaa acctctccat 300 ttcaaaggat gcccttttca tcgaattatt aagaaattta tgattcaggg tggagacttc 360 tcaaatcaga atgggacagg tggagaaagt atttatggtg aaaaatttga agatgaaaat 420 ttccattaca agcatgatcg ggagggttta ctgagcatgg caaatgcagg ccgcaacaca 480 aacggttctc agttttttat cacaacagtt ccaactcctc atttggatgg gaaacatgtg 540 gtgtttggcc aagtaattaa aggaatagga gtggcaagga tattggaaaa tgtggaagtg 600 aaaggtgaaa aacctgctaa attgtgcgtt attgcagaat gtggagaatt gaaggaagga 660 gatgacgggg gaatattccc aaaagatggc tctggcgaca gtcatccaga tttccctgag 720 gatgcggata tagatttaaa agatgtagat aaaattttat taataacaga agacttaaaa 780 aacattggaa atactttttt caaatcccag aactgggaga tggctattaa aaaatatgca 840 gaagttttaa gatacgtgga cagttcaaag gctgttattg agacagcaga tagagccaag 900 ctgcaaccta tagctttaag ctgtgtactg aatattggtg cttgtaaact gaagatgtca 960 aattggcagg gagcaattga cagttgttta gaggctcttg aactagaccc atcaaatacc 1020 aaagcattgt accgcagagc tcaaggatgg caaggattaa aagaatatga tcaagcattg 1080 gctgatctta agaaagctca ggggatagca ccagaagata aagctatcca ggcagaattg 1140 ctgaaagtca aacaaaagat aaaggcacag aaagataaag agaaggcagt atatgcaaaa 1200 atgtttgctt agaaaggatt cagttttgct tattgtgtgt tgattgtata aatgcaataa 1260 gaaaatgtaa aggtttttgt ctatgaatat gatccctaat gtgtttcttt tgacacctta 1320 gttccttact gtttacagtt taggagtact gataggggtt catgcttaat aaacatgtca 1380 caatacagta agtaaagtgg ttttgtttgt ttctttgaga tggagtcttg ctctgtcacc 1440 caggctggag tgcggtggcg caatctcggc tcactgcatc ctctgcctcc cgggttcaag 1500 caattctcct gcctcagctt cccaagtagc tgggattaca ggcacgtgcc accacgccca 1560 gactaatttt tgtattttta gtagagatgg ggtttcacca tattggtcac gtcacgttgg 1620 tcttgaactc ctgaccttgt gatccacccc gccttggcct cccaaagtgc tgggattaca 1680 ggtgtgagcc accgtgcccg gccaagtaaa atgtttttta aaatggttat gtgcattatt 1740 cataaaaaat aatggtgtcc agtcttttta aacttgtaaa gacacatctt attgaataaa 1800 gagatgagag cg 1812 <210> 111 <211> 1792 <212> DNA <213> HUMAN <400> 111 cagcgcgatg tgggttcccg gcttcggatc cgcgcgactt ccccagcgcc ggcgctccgg 60 gttggagtca tcctcggtgc ggccgctgtg gctgctgctg ctgttcctgc tggcagccgt 120 gcggccagtg cgcgcctggg agagcggaga cctggagttg ttcgacttgg tggaagaggt 180 gcagttgaac ttctacgagt tcctcggggt gcagcaggat gcttcatctg cagacatcag 240 aaaagcatat cgtaagcttt cactaacctt acatccagac aagaataaag atgaaaatgc 300 agaaactcaa tttagacaat tggtggccat ttatgaagtt ttaaaggatg atgaaagaag 360 gcagaggtat gatgatgttc tgatcaatgg acttccagat tggcgacagc ctgtattcta 420 ctacaggcga gtgagaaaaa tgagcaatgc tgagctggct ttgctcttgt tcattattct 480 cacagtgggt cactatgctg tggtttggtc catctacctg gaaaagcaac tggatgaact 540 gcttggtaga aaaaagagag aaaggaagaa gaagacagga agcaagagtg tggacgcagc 600 aaaacttggt gcttctgaaa agaacgaaag attgcttata aaaccacaat ggcatgattt 660 gcttccatgc aaactgggga tttggttttg ccttacacta aaagcattgc ctcatctaat 720 ccaggatgct gggcagtttt atgcaaaata taaggagaca aaattgaagg aaaaagaaga 780 cgcactggct agaattgaaa ttgaaaccct tcaaaaacag aagaaagtta aagttaaaaa 840 accaaaacca gaatttcctg tgtatatgcc tttagaaaat acgtatattc agtcttatga 900 tcatggaact tctattgaag aaattgagga gcaaatggat gactggctgg aaaacaggaa 960 aagaacacag aaaagacagg cacctgaatg gacagaagag gacctcagtc aactgacaag 1020 aagtatggtt aagttcccag gagggactcc aggtcgatgg gacaagattg cccatgaatt 1080 gggtcgatct gtgacagatg tgacaaccaa agccaaggaa ctgaaggact cagtcaccag 1140 ctcccccgga atgaccaggc tctctgaact taagtcaaat ggtcagaatt ccaggccaat 1200 caagatagcc acagccttgc cagatgacat catcacgcag cgggaggact cagcaggggc 1260 catggaggat gaggagcacg aggctgctga gggtgagcag gagtcagcga ccacagaagc 1320 ccgacctcgg aggcggaagt cagccagggc ggccgaggct gtaaccagag tggagccaga 1380 ggagaagctg agaggaaaga ggcaaaaaga ctttgatata tcagaacaaa acgattccag 1440 tgacgaagag aaacaacgaa aagaaagaac tcgtgctgca gaggaggcgt ggactcagag 1500 tcagcagaaa cttctggaat tggcattaca gcaataccct aaaggagctt ctgaccgctg 1560 ggacaaaata gccaaatgtg tcccgtctaa gagtaaggaa gactgcattg ctagatacaa 1620 gctgctggtt gaactggtcc aaaagaaaaa gcaggctaaa agctgaatct tctggaaggt 1680 gacgatcaat gaccatcatt ttccaaacaa gtactcgaga aatctcatgc agaaacttat 1740 attttgtacc tcagtatttc taaacatcat gtgccttagt aaaaaaaaaa aa 1792 <210> 112 <211> 3457 <212> DNA <213> HUMAN <400> 112 cctccacctc ccgggttcaa gcgattctcc tgcctcagcc tcccgagtag ctgagactac 60 aggcacgcgc caccacgccc agctaatttt tgtatcttta gtagagacgg gctttcacca 120 tgttggccag gatggtctcg atgtcttaac gtcgtgatcc ggccgcctcg gcctcccaag 180 tgctgggatt acaggcgtta gccactgcgc ccggccccag ccaggcagtt ttaatcgagc 240 gctcacaacc actgagacgc agcgaagcac ccaccataat atcccaggag gccgaccgcc 300 ggttcagact ttttcttttc tttaatcccc gtccaaggga tccgccctca ccccccaccc 360 cagccacccc aattccctat tccctcccct tggacggcgc cggggaaaac aagctgctcg 420 agctttattt cttcggtgca accaactcag aatgaattcc tccgcccctg cgtgctcagt 480 gagtcggcac cctagcagtg aactgcattt aaaacctcag gaattgagcg aactctccca 540 gtggctctcc tcaccgggat ccccttccac gcctcctccc cgtgccgcgc ctcagtccgc 600 actgctcatt ggccgcgtgc ctgccaatcc gatgcacgtc ggctagggca aagaccgcga 660 aaaagcgcgt acacctggct ctgggagcgc gcgcctaacg ccagccagca gcaggaggcg 720 cgcgaggcac cacggcctgg cggccgagag tcagggagga acctcattta cataacggcc 780 gcccctctgt ctcctggcgg gggccggagt cccgcccctc gtccaacttg aaatctgttg 840 ggtcacgggc cagtcactcc gacctaggca agcctgtggt ggagctggaa gagtttgtga 900 gggcggtccc gggagcggat tgggtctggg agttcccaga ggcggctata agaaccggga 960 actgggcgcg gggagctgag ttgctggtag tgcccgtggt gcttggttcg aggtggccgt 1020 tagttgactc cgcggagttc atctccctgg ttttcccgtc ctaacgtcgc tcgcctttca 1080 gtcaggatgt ctgcccgtgg cccggctatc ggcatcgacc tgggcaccac ctattcgtgc 1140 gtcggggtct tccaacatgg caaggtggag atcatcgcca acgaccaggg caatcgcacc 1200 acccccagct acgtggcctt cacggacacc gagcgcctca tcggcgacgc cgccaagaac 1260 caggtggcca tgaaccccac caacaccatc ttcgacgcca agaggctgat tggacggaaa 1320 ttcgaggatg ccacagtgca gtcggatatg aaacactggc cgttccgggt ggtgagcgag 1380 ggaggcaagc ccaaagtgca agtagagtac aagggggaga ccaagacctt cttcccagag 1440 gagatatcct ccatggtcct cacgaagatg aaggagatcg cggaagccta cctggggggc 1500 aaggtgcaca gcgcggtcat aacggtcccg gcctatttca acgactcgca gcgccaggcc 1560 accaaggacg caggcaccat cacggggctc aatgtgctgc gcatcatcaa cgagcccacg 1620 gcggcggcca tcgcctacgg cctggacaag aagggctgcg cgggcggcga gaagaacgtg 1680 ctcatctttg acctgggcgg tggcactttc gacgtgtcca tcctgaccat cgaggatggc 1740 atcttcgagg tgaagtccac ggccggcgat acccacctgg gcggtgagga cttcgacaac 1800 cgcatggtga gccacctggc ggaggagttc aagcgcaagc acaagaagga cattgggccc 1860 aacaagcgcg ccgtgaggcg gctgcgcacc gcttgcgagc gcgccaagcg caccctgagc 1920 tcgtccacgc aggcgagcat cgagatcgac tcgctctacg agggcgtgga cttctatacg 1980 tccatcacgc gcgcccgctt cgaggagctc aatgccgacc tctttcgcgg gaccctggag 2040 ccggtggaga aggcgctgcg cgacgccaag ctggacaagg gccagatcca ggagatcgtg 2100 ctggtgggcg gctccactcg tatccccaag atccagaagc tgctgcagga tttcttcaac 2160 ggcaaggagc tgaacaagag catcaacccc gacgaggcgg tggcctatgg cgccgcggtg 2220 caggcggcca tcctcatcgg cgacaaatca gagaatgtgc aggacctgct gctactcgac 2280 gtgaccccgt tgtcgctggg catcgagaca gctggcggtg tcatgacccc actcatcaag 2340 aggaacacca cgatccccac caagcagacg cagaccttca ccacctactc ggacaaccag 2400 agcagcgtac tggtgcaggt atacgagggc gaacgggcca tgaccaagga caataacctg 2460 ctgggcaagt tcgacctgac cgggattccc cctgcgcctc gcggggtccc ccaaatcgag 2520 gttaccttcg acattgacgc caatggcatc cttaacgtta ccgccgccga caagagcacc 2580 ggtaaggaaa acaaaatcac catcaccaat gacaaaggtc gtctgagcaa ggacgacatt 2640 gaccggatgg tgcaggaggc ggagcggtac aaatcggaag atgaggcgaa tcgcgaccga 2700 gtcgcggcca aaaacgccct ggagtcctat acctacaaca tcaagcagac ggtggaagac 2760 gagaaactga ggggcaagat tagcgagcag gacaaaaaca agatcctcga caagtgtcag 2820 gaggtgatca actggctcga ccgaaaccag atggcagaga aagatgagta tgaacacaag 2880 cagaaagagc tcgaaagagt ttgcaacccc atcatcagca aactttacca aggtggtcct 2940 ggcggcggca gcggcggcgg cggttcagga gcctccgggg gacccaccat cgaagaagtg 3000 gactaagctt gcactcaagt cagcgtaaac ctctttgcct ttctctctct ctcttttttt 3060 tttgtttgtt tctttgaaat gtccttgtgc caagtacgag atctattgtt ggaagtcttt 3120 ggtatatgca aatgaaagga gaggtgcaac aacttagttt aattataaaa gttccaaagt 3180 ttgtttttta aaaacattat tcgaggtttc tctttaatgc attttgcgtg tttgctgact 3240 tgagcatttt tgattagttc gtgcatggag atttgtttga gatgagaaac cttaagtttg 3300 cacacctgtt ctgtagaagc ttggaaacag taaaatatat aggagcttaa attgtttatt 3360 tttatgtact actttaaaac taaactgaac attgcagtaa tgttaaggac aggtatactt 3420 tttgcaaaca aatgcataaa tgcaaatgta aagtaaa 3457 <210> 113 <211> 1365 <212> DNA <213> HUMAN <400> 113 ataattccat ccctcctcca acttttccct ctcaagctct gcccttccca gcccagccca 60 gcctacccaa cctcatctct tccctgtaga ccacatccca ccatgttccc ctgagcctcc 120 aaggaagggg ctcaggggcc ccatggcctc ccgctccctg tggccccaca gcccccgtgg 180 gccaggggaa gcgccccaga agccgaagtg cccaccatgg gcaaccacac gtgggagggc 240 tgccacgtgg actcgcgcgt ggaccacctc tttccgccat ccctctacat ctttgtcatc 300 ggcgtggggc tgcccaccaa ctgcctggct ctgtgggcgg cctaccgcca ggtgcaacag 360 cgcaacgagc tgggcgtcta cctgatgaac ctcagcatcg ccgacctgct gtacatctgc 420 acgctgccgc tgtgggtgga ctacttcctg caccacgaca actggatcca cggccccggg 480 tcctgcaagc tctttgggtt catcttctac accaatatct acatcagcat cgccttcctg 540 tgctgcatct cggtggaccg ctacctggct gtggcccacc cactccgctt cgcccgcctg 600 cgccgcgtca agaccgccgt ggccgtgagc tccgtggtct gggccacgga gctgggcgcc 660 aactcggcgc ccctgttcca tgacgagctc ttccgagacc gctacaacca caccttctgc 720 tttgagaagt tccccatgga aggctgggtg gcctggatga acctctatcg ggtgttcgtg 780 ggcttcctct tcccgtgggc gctcatgctg ctgtcgtacc ggggcatcct gcgggccgtg 840 cggggcagcg tgtccaccga gcgccaggag aaggccaaga tcaagcggct ggccctcagc 900 ctcatcgcca tcgtgctggt ctgctttgcg ccctatcacg tgctcttgct gtcccgcagc 960 gccatctacc tgggccgccc ctgggactgc ggcttcgagg agcgcgtctt ttctgcatac 1020 cacagctcac tggctttcac cagcctcaac tgtgtggcgg accccatcct ctactgcctg 1080 gtcaacgagg gcgcccgcag cgatgtggcc aaggccctgc acaacctgct ccgctttctg 1140 gccagcgaca agccccagga gatggccaat gcctcgctca ccctggagac cccactcacc 1200 tccaagagga acagcacagc caaagccatg actggcagct gggcggccac tccgcctccc 1260 agggggacca ggtgcagctg aagatgctgc cgccagcaca atgaaccccg agtggcacag 1320 aatccccagt tttcccctct catcccacag tcccttctct cctgg 1365 <210> 114 <211> 444 <212> DNA <213> HUMAN <400> 114 tttttcatgc tcattgctgt ttattgaaac aaaagaatca gaagaagatc agaatgaaga 60 caataataaa aagcagaagc agaagtacaa gaagaataaa gaaagaaagg gaaagaattg 120 taggaaggaa aaacttgtag aagtagaggg tggagagtgc gaagaggtgg agtatgatgg 180 gcagtccgat cttttccatc tgggctttca gacaatggga tatgtcatgg aaggcttctt 240 taaacaccag aagaaattca ggataaagct caaaaagagc aggcaatcga taggggttga 300 aaatccactc agtaggccac ggaaggactt caagaaggtt gatcgttctg tcgctggatg 360 ttgtaggtgt cctacgtgaa ggcaatcgac atctggatgg ctgtgtgtcg gctctttgtg 420 ttcgctgcct tgctggagta tgcc 444 <210> 115 <211> 383 <212> DNA <213> HUMAN <400> 115 ggtgcgcatg cgcatcacct gggcggcacc cgcggtactg cgcctgcgcg gtctcgccgc 60 ttcccaggtc cgctccgcag ggcgagcgcg cgccagtccc actcgtgcgc cgctcttcat 120 gtccccgcgg tcgaagacgg tcacatacgc ccccaagaaa acgtcgccga ggatccacac 180 aggtactgga ggcgaacgat gtccaaggcc cggaagccgg acaagcagag gcggacgtca 240 ccctgagcaa actggatgac gtaatcctgg gccgtgagat taaaccagac ccccccaatg 300 aggagtgaga ctgcggggag ctttgggatt tctgagcacc ggatgatgta ctccccagcc 360 agcaaggggg attcccccaa tgg 383 <210> 116 <211> 343 <212> DNA <213> HUMAN <400> 116 gcggttctgg ccatgaagcc cacctcaggc ccagaggagg cccggcggca gcctcggaca 60 tccgcgtgtt cgccagcaac tgctcgatgc acgggctggg cacgtcttcg ggccaggcag 120 cctgagcctg cgccggggga tgtgggcagc ggcgtggtcc tgtcagtggc caccttcctc 180 taccaggtgg ctgagagggt gcgctactac agggagttcc accaccagac tgccctggat 240 gagcgagaaa gccaccggtc agtcttcccg gctgtcaccc tgtgcaacat caacccactg 300 cgccgctcgc gcctaacgcc caacgacctg cactgggctg ggt 343 <210> 117 <211> 308 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(308) <223> N=any base <400> 117 gggcaagtcc agtgcagacg tgcgggctct gacctactgc gacntgcana agatccagcg 60 ggcagatctg ctggaggtgc tggacatgta cccggccttt gcggagagct tctggagtaa 120 gctggaggtc accttcaacc tgcgggacnc acgggggtct ccactcatcc ccccgacagc 180 tcctggcagc caagaccacc aaggtttctt tctcagtgac aacagtcaga tgcagcccct 240 nccctggagc atctcagatg catctggcct ctgctggagn cttactgnag ggaaatgccc 300 ccaaggca 308 <210> 118 <211> 366 <212> DNA <213> HUMAN <400> 118 atgaaggtct ccgtggctgc cctctcctgc ctacatgcct ttttactgcc cttggtccca 60 gggccgggtc acaaaagatg cagagacaga gttcatgaat gtcaaagctt cattggaaag 120 atccagtact tctgggacag attccatgct actagtgctg actgctgcat ctcctacacc 180 ccacgaagca tcccgtgttc actcctggag agttactttg aaacgaacag cgagtgctcc 240 aagccgggtg tcatcttcct caccaagaag gggcgacgtt tctgtgccaa ccccagtgat 300 aagcaagttc aggtttgcat gagaatgctg aagctggaca cacggatcaa gaccaggaag 360 aattga 366 <210> 119 <211> 2313 <212> DNA <213> HUMAN <400> 119 ccgagccgca gtttccgtgt tgtgagtgag tccgggcccg tgtcccctct cccgccgccg 60 ccatgggctg cacgttgagc gccgaagaca aggcggcagt ggagcgaagc aagatgatcg 120 accgcaactt acgggaggac ggggaaaaag cggccaaaga agtgaagctg ctgctactcg 180 gtgctggaga atctggtaaa agcaccattg tgaaacagat gaaaatcatt catgaggatg 240 gctattcaga ggatgaatgt aaacaatata aagtagttgt ctacagcaat actatacagt 300 ccatcattgc aatcataaga gccatgggac ggctaaagat tgactttggg gaagctgcca 360 gggcagatga tgcccggcaa ttatttgttt tagctggcag tgctgaagaa ggagtcatga 420 ctccagaact agcaggagtg attaaacggt tatggcgaga tggtggggta caagcttgct 480 tcagcagatc cagggaatat cagctcaatg attctgcttc atattatcta aatgatctgg 540 atagaatatc ccagtctaac tacattccaa ctcagcaaga tgttcttcgg acgagagtga 600 agaccacagg cattgtagaa acacatttca ccttcaaaga cctatacttc aagatgtttg 660 atgtaggtgg ccaaagatca gaacgaaaaa agtggattca ctgttttgag ggagtgacag 720 caattatctt ctgtgtggcc ctcagtgatt atgaccttgt tctggctgag gacgaggaga 780 tgaaccgaat gcatgaaagc atgaaactgt ttgacagcat ttgtaataac aaatggttta 840 cagaaacttc aatcattctc ttccttaaca agaaagacct ttttgaggaa aaaataaaga 900 ggagtccgtt aactatctgt tatccagaat acacaggttc caatacatat gaagaggcag 960 ctgcctatat tcaatgccag tttgaagatc tgaacagaag aaaagatacc aaggagatct 1020 atactcactt cacctgtgcc acagacacga agaatgtgca gtttgttttt gatgctgtta 1080 cagatgtcat cattaaaaac aacttaaagg aatgtggact ttattgagaa gcatggatgt 1140 tagtgaaagt tactacagtg tggagtgttg agaccagaca ccttttgctg tctcatgggg 1200 cagctacaag catgaacggg accagggaat ggcagcagca tgcagaatct tagcactctt 1260 tagcacaata ttttgtatta gggaactttt aattgacatg agatgctaaa gtcagacatt 1320 ggaattggaa gaactataaa gtgtgattcg atcgtcaaga catcacttgg atttcttaat 1380 cttaaatgct tatggaagat gtgaagttga ggtgctgcat tctagaactt caatatgtag 1440 cttactcttt ttttcccccc ttcttaaacc accagtggtt catttttaag gttttttcat 1500 caagagaaga ataactttac taaattttat ttctttattt gcaaaagaat ctttattaaa 1560 acaaacaatc ttaactatgc acatgatgtg accagatcat cttgaaaata ttcctcttta 1620 gtaggaactc tttgttttta actcttggta tggtcagaat ataatacttc cataattact 1680 tataattctt tccggttact ggggctataa atacaacttt ttaaatgaaa tttatgttat 1740 tatcctgctc aaagtaccat tatggtttcc atatggtaat tacattggaa agttctgcaa 1800 taagattcta gttctctctt ttctttaagc ttatggttga aggttaacct tgtttgtgca 1860 gattaccaaa ttactgctga tgtagtatga taaagtcagc ttcttggata cagacacacc 1920 cagggcagct gccaatcaga aatgcaaatt gctaaattcc aaacagaacc agtgactttg 1980 ctgctacata tttactaaat tgaccacttt gattcttgct tgtttgtctc agttataggg 2040 agttttgtac atggtgcctc ttgttttcca tcttcatggc cttttctgtt gagaaacatc 2100 taaagtgtat taacagtgca tgcttttact ttgtaaatgt ggtgccaaat ccctgtttgc 2160 catcgttttt actgtaccga tgttaactgt agtaatcctt agccagtatg ttcttttgct 2220 gaaactgttg cattttggga cttttttcca ctttgtcatg tgtacatttt taatctgtta 2280 tagttggcgg cagtattaaa atggtgagta aag 2313 <210> 120 <211> 4604 <212> DNA <213> HUMAN <400> 120 ggaacagctt gtccacccgc cggccggacc agaagccttt gggtctgaag tgtctgtgag 60 acctcacaga agagcacccc tgggctccac ttacctgccc cctgctcctt cagggatgga 120 ggcaatggcg gccagcactt ccctgcctga ccctggagac tttgaccgga acgtgccccg 180 gatctgtggg gtgtgtggag accgagccac tggctttcac ttcaatgcta tgacctgtga 240 aggctgcaaa ggcttcttca ggcgaagcat gaagcggaag gcactattca cctgcccctt 300 caacggggac tgccgcatca ccaaggacaa ccgacgccac tgccaggcct gccggctcaa 360 acgctgtgtg gacatcggca tgatgaagga gttcattctg acagatgagg aagtgcagag 420 gaagcgggag atgatcctga agcggaagga ggaggaggcc ttgaaggaca gtctgcggcc 480 caagctgtct gaggagcagc agcgcatcat tgccatactg ctggacgccc accataagac 540 ctacgacccc acctactccg acttctgcca gttccggcct ccagttcgtg tgaatgatgg 600 tggagggagc catccttcca ggcccaactc cagacacact cccagcttct ctggggactc 660 ctcctcctcc tgctcagatc actgtatcac ctcttcagac atgatggact cgtccagctt 720 ctccaatctg gatctgagtg aagaagattc agatgaccct tctgtgaccc tagagctgtc 780 ccagctctcc atgctgcccc acctggctga cctggtcagt tacagcatcc aaaaggtcat 840 tggctttgct aagatgatac caggattcag agacctcacc tctgaggacc agatcgtact 900 gctgaagtca agtgccattg aggtcatcat gttgcgctcc aatgagtcct tcaccatgga 960 cgacatgtcc tggacctgtg gcaaccaaga ctacaagtac cgcgtcagtg acgtgaccaa 1020 agccggacac agcctggagc tgattgagcc cctcatcaag ttccaggtgg gactgaagaa 1080 gctgaacttg catgaggagg agcatgtcct gctcatggcc atctgcatcg tctccccaga 1140 tcgtcctggg gtgcaggacg ccgcgctgat tgaggccatc caggaccgcc tgtccaacac 1200 actgcagacg tacatccgct gccgccaccc gcccccgggc agccacctgc tctatgccaa 1260 gatgatccag aagctagccg acctgcgcag cctcaatgag gagcactcca agcagtaccg 1320 ctgcctctcc ttccagcctg agtgcagcat gaagctaacg ccccttgtgc tcgaagtgtt 1380 tggcaatgag atctcctgac taggacagcc tgtgcggtgc ctgggtgggg ctgctcctcc 1440 agggccacgt gccaggcccg gggctggcgg ctactcagca gccctcctca cccgtctggg 1500 gttcagcccc tcctctgcca cctcccctat ccacccagcc cattctctct cctgtccaac 1560 ctaacccctt tcctgcgggc ttttccccgg tcccttgaga cctcagccat gaggagttgc 1620 tgtttgtttg acaaagaaac ccaagtgggg gcagagggca gaggctggag gcaggccttg 1680 cccagagatg cctccaccgc tgcctaagtg gctgctgact gatgttgagg gaacagacag 1740 gagaaatgca tccattcctc agggacagag acacctgcac ctccccccac tgcaggcccc 1800 gcttgtccag cgcctagtgg ggtctccctc tcctgcctta ctcacgataa ataatcggcc 1860 cacagctccc accccacccc cttcagtgcc caccaacatc ccattgccct ggttatattc 1920 tcacgggcag tagctgtggt gaggtgggtt ttcttcccat cactggagca ccaggcacga 1980 acccacctgc tgagagaccc aaggaggaaa aacagacaaa aacagcctca cagaagaata 2040 tgacagctgt ccctgtcacc aagctcacag ttcctcgccc tgggtctaag gggttggttg 2100 aggtggaagc cctccttcca cggatccatg tagcaggact gaattgtccc cagtttgcag 2160 aaaagcacct gccgacctcg tcctccccct gccagtgcct tacctcctgc ccaggagagc 2220 cagccctccc tgtcctcctc ggatcaccga gagtagccga gagcctgctc ccccaccccc 2280 tccccagggg agagggtctg gagaagcagt gagccgcatc ttctccatct ggcagggtgg 2340 gatggaggag aagaattttc agaccccagc ggctgagtca tgatctccct gccgcctcaa 2400 tgtggttgca aggccgctgt tcaccacagg gctaagagct aggctgccgc accccagagt 2460 gtgggaaggg agagcggggc agtctcgggt ggctagtcag agagagtgtt tgggggttcc 2520 gtgatgtagg gtaaggtgcc ttcttattct cactccacca cccaaaagtc aaaaggtgcc 2580 tgtgaggcag gggcggagtg atacaacttc aagtgcatgc tctctgcagg tcgagcccag 2640 cccagctggt gggaagcgtc tgtccgttta ctccaaggtg ggtctttgtg agagtgagct 2700 gtaggtgtgc gggaccggta cagaaaggcg ttcttcgagg tggatcacag aggcttcttc 2760 agatcaatgc ttgagtttgg aatcggccgc attccctgag tcaccaggaa tgttaaagtc 2820 agtgggaacg tgactgcccc aactcctgga agctgtgtcc ttgcacctgc atccgtagtt 2880 ccctgaaaac ccagagagga atcagacttc acactgcaag agccttggtg tccacctggc 2940 cccatgtctc tcagaattct tcaggtggaa aaacatctga aagccacgtt ccttactgca 3000 gaatagcata tatatcgctt aatcttaaat ttattagata tgagttgttt tcagactcag 3060 actccatttg tattatagtc taatatacag ggtagcaggt accactgatt tggagatatt 3120 tatgggggga gaacttacat tgtgaaactt ctgtacatta attattattg ctgttgttat 3180 tttacaaggg tctagggaga gacccttgtt tgattttagc tgcagaactg tattggtcca 3240 gcttgctctt cagtgggaga aaaacacttg taagttgcta aacgagtcaa tcccctcatt 3300 caggaaaact gacagaggag ggcgtgactc acccaagcca tatataacta gctagaagtg 3360 ggccaggaca ggccgggcgc ggtggctcac gcctgtaatc ccagcagttt gggaggtcga 3420 ggtaggtgga tcacctgagg tcgggagttc gagaccaacc tgaccaacat ggagaaaccc 3480 tgtctctatt aaaaatacaa aaaaaaaaaa aaaaaaaaat agccgggcat ggtggcgcaa 3540 gcctgtaatc ccagctactc aggaggctga ggcagaagaa ttgaacccag gaggtggagg 3600 ttgcagtgag ctgagatcgt gccgttactc tccaacctgg acaacaagag cgaaactccg 3660 tcttagaagt ggaccaggac aggaccagat tttggagtca tggtccggtg tccttttcac 3720 tacaccatgt ttgagctcag acccccactc tcattcccca ggtggctgac ccagtccctg 3780 ggggaagccc tggatttcag aaagagccaa gtctggatct gggacccttt ccttccttcc 3840 ctggcttgta actccaccaa gcccatcaga aggagaagga aggagactca cctctgcctc 3900 aatgtgaatc agaccctacc ccaccacgat gtgccctggc tgctgggctc tccacctcag 3960 gccttggata atgctgttgc ctcatctata acatgcattt gtctttgtaa tgtcaccacc 4020 ttcccagctc tccctctggc cctgcttctt cggggaactc ctgaaatatc agttactcag 4080 ccctgggccc caccacctag gccactcctc caaaggaagt ctaggagctg ggaggaaaag 4140 aaaagagggg aaaatgagtt tttatggggc tgaacgggga gaaaaggtca tcatcgattc 4200 tactttagaa tgagagtgtg aaatagacat ttgtaaatgt aaaactttta aggtatatca 4260 ttataactga aggagaaggt gccccaaaat gcaagatttt ccacaagatt cccagagaca 4320 ggaaaatcct ctggctggct aactggaagc atgtaggaga atccaagcga ggtcaacaga 4380 gaaggcagga atgtgtggca gatttagtga aagctagaga tatggcagcg aaaggatgta 4440 aacagtgcct gctgaatgat ttccaaagag aaaaaaagtt tgccagaagt ttgtcaagtc 4500 aaccaatgta gaaagctttg cttatggtaa taaaaatggc tcatacttat atagcactta 4560 ctttgtttgc aagtactgct gtaaataaat gctttatgca aacc 4604 <210> 121 <211> 1050 <212> DNA <213> HUMAN <400> 121 ctcgccagct cttccgctcc tctcacagcc gccagacccg cctgctgagc cccatggccc 60 gcgctgctct ctccgccgcc cccagcaatc cccggctcct gcgagtggca ctgctgctcc 120 tgctcctggt agccgctggc cggcgcgcag caggagcgtc cgtggccact gaactgcgct 180 gccagtgctt gcagaccctg cagggaattc accccaagaa catccaaagt gtgaacgtga 240 agtcccccgg accccactgc gcccaaaccg aagtcatagc cacactcaag aatgggcgga 300 aagcttgcct caatcctgca tcccccatag ttaagaaaat catcgaaaag atgctgaaca 360 gtgacaaatc caactgacca gaagggagga ggaagctcac tggtggctgt tcctgaagga 420 ggccctgccc ttataggaac agaagaggaa agagagacac agctgcagag gccacctgga 480 ttgtgcctaa tgtgtttgag catcgcttag gagaagtctt ctatttattt atttattcat 540 tagttttgaa gattctatgt taatatttta ggtgtaaaat aattaagggt atgattaact 600 ctacctgcac actgtcctat tatattcatt ctttttgaaa tgtcaacccc aagttagttc 660 aatctggatt catatttaat ttgaaggtag aatgttttca aatgttctcc agtcattatg 720 ttaatatttc tgaggagcct gcaacatgcc agccactgtg atagaggctg gcggatccaa 780 gcaaatggcc aatgagatca ttgtgaaggc aggggaatgt atgtgcacat ctgttttgta 840 actgtttaga tgaatgtcag ttgttattta ttgaaatgat ttcacagtgt gtggtcaaca 900 tttctcatgt tgaaacttta agaactaaaa tgttctaaat atcccttgga cattttatgt 960 ctttcttgta aggcatactg ccttgtttaa tggtagtttt acagtgtttc tggcttagaa 1020 caaaggggct taattattga tgttttcgga 1050 <210> 122 <211> 2754 <212> DNA <213> HUMAN <400> 122 gaattccgcc agccccgcca gtccccgcgc agtccccgcg cagtcccagc gccaccgggc 60 agcagcggcg ccgtgctcgc tccagggcgc aaccatgtcg ccatttcttc ggattggctt 120 gtccaacttt gactgcgggt cctgccagtc ttgtcagggc gaggctgtta acccttactg 180 tgctgtgctc gtcaaagagt atgtcgaatc agagaacggg cagatgtata tccagaaaaa 240 gcctaccatg tacccaccct gggacagcac ttttgatgcc catatcaaca agggaagagt 300 catgcagatc attgtgaaag gcaaaaacgt ggacctcatc tctgaaacca ccgtggagct 360 ctactcgctg gctgagaggt gcaggaagaa caacgggaag acagaaatat ggttagagct 420 gaaacctcaa ggccgaatgc taatgaatgc aagatacttt ctggaaatga gtgacacaaa 480 ggacatgaat gaatttgaga cggaaggctt ctttgctttg catcagcgcc ggggtgccat 540 caagcaggca aaggtccacc acgtcaagtg ccacgagttc actgccacct tcttcccaca 600 gcccacattt tgctctgtct gccacgagtt tgtctggggc ctgaacaaac agggctacca 660 gtgccgacaa tgcaatgcag caattcacaa gaagtgtatt gataaagtta tagcaaagtg 720 cacaggatca gctatcaata gccgagaaac catgttccac aaggagagat tcaaaattga 780 catgccacac agatttaaag tctacaatta caagagcccg accttctgtg aacactgtgg 840 gaccctgctg tggggactgg cacggcaagg actcaagtgt gatgcatgtg gcatgaatgt 900 gcatcataga tgccagacaa aggtggccaa cctttgtggc ataaaccaga agctaatggc 960 tgaagcgctg gccatgattg agagcactca acaggctcgc tgcttaagag atactgaaca 1020 gatcttcaga gaaggtccgg ttgaaattgg tctcccatgc tccatcaaaa atgaagcaag 1080 gctgccatgt ttaccgacac cgggaaaaag agagcctcag ggcatttcct gggagtctcc 1140 gttggatgag gtggataaaa tgtgccatct tccagaacct gaactgaaca aagaaagacc 1200 atctctgcag attaaactaa aaattgagga ttttatcttg cacaaaatgt tggggaaagg 1260 aagttttggc aaggtcttcc tggcagaatt caagaaaacc aatcaatttt tcgcaataaa 1320 ggccttaaag aaagatgtgg tcttgatgga cgatgatgtt gagtgcacga tggtagagaa 1380 gagagttctt tccttggcct gggagcatcc gtttctgacg cacatgtttt gtacatttca 1440 gaccaaggaa aacctctttt ttgtgatgga gtacctcaac ggaggggact taatgtacca 1500 catccaaagc tgccacaagt tcgacctttc cagagcgacg ttttatgctg ctgaaatcat 1560 tcttggtctg cagttccttc attccaaagg aatagtctac agggacctga agctagataa 1620 catcctgtta gacaaagatg gacatatcaa gatcgcggat tttggaatgt gcaaggagaa 1680 catgttagga gatgccaaga cgaatacctt ctgtgggaca cctgactaca tcgccccaga 1740 gatcttgctg ggtcagaaat acaaccactc tgtggactgg tggtccttcg gggttctcct 1800 ttatgaaatg ctgattggtc agtcgccttt ccacgggcag gatgaggagg agctcttcca 1860 ctccatccgc atggacaatc ccttttaccc acggtggctg gagaaggaag caaaggacct 1920 tctggtgaag ctcttcgtgc gagaacctga gaagaggctg ggcgtgaggg gagacatccg 1980 ccagcaccct ttgtttcggg agatcaactg ggaggaactt gaacggaagg agattgaccc 2040 accgttccgg ccgaaagtga aatcaccatt tgactgcagc aatttcgaca aagaattctt 2100 aaacgagaag ccccggctgt catttgccga cagagcactg atcaacagca tggaccagaa 2160 tatgttcagg aacttttcct tcatgaaccc ccggatggag cggctgatat cctgaatctt 2220 gcccctccag agacaggaaa gaatttgcct tgtccctggg aactggttca agagacactg 2280 cttgggttcc tttttcaact tggaaaaaga aagaaacact caacaataaa gactgagacc 2340 cgttcgcccc catgtgactt ttatctgtag cagaaaccaa gtctacttca ctaatgacga 2400 tgccgtgtgt ctcgtctcct gacatgtctc acagacgctc ctgaagttag gtcattacta 2460 accatagtta tttacttgaa agatgggtct ccgcacttgg aaaggtttca agacttgata 2520 ctgcaataaa ttatggctct tcacctgggc gccaactgct gatcaacgaa atgcttgttg 2580 aatcaggggc aaacggagta cagacgtctc aagactgaaa cggccccatt gcctggtcta 2640 gtagcggatc tcactcagcc gcagacaagt aatcactaac ccgttttatt ctattcctat 2700 ctgtggatgg gtaaatgctg ggggccagcc ctggataggt ttttatggga attc 2754 <210> 123 <211> 3606 <212> DNA <213> HUMAN <400> 123 gcggaagagc agaacgtttg ggagtgtgca gctcctgggc ccggctcagg cccgtcgcgg 60 aggcgcggcg caggggagcg ctcgggtggg agtctcgctc ctccaccagt ttattgcgac 120 gtagcatcca ggcctaggcc tccccgtcca tccccgccgg actcgggcct ctggcagcag 180 cgggtgacgc agacggaaca tcatgtcgtc cgcggccgag cctccgccac ccccgcctcc 240 cgagagcgcg ccttccaagc ccgcagcctc gatcgccagc ggcgggagca acagcagcaa 300 caaaggcggc cccgaaggcg tcgcggcgca ggcggttgcg tctgcggcca gcgctggtcc 360 cgcagacgcc gagatggagg aaatatttga tgatgcgtca cctggaaagc aaaaggaaat 420 ccaagaacca gatcctacct atgaagaaaa aatgcaaact gaccgggcaa atagattcga 480 gtatttatta aagcagacag aactttttgc acatttcatt caacctgctg ctcagaagac 540 tccaacttca cctttgaaga tgaaaccagg gcgcccacga ataaaaaaag atgagaagca 600 gaacttacta tccgttggcg attaccgaca ccgtagaaca gagcaagagg aggatgaaga 660 gctattaaca gaaagctcca aagcaaccaa tgtttgcact cgatttgaag actctccatc 720 gtatgtaaaa tggggtaaac tgagagatta tcaggtccga ggattaaact ggctcatttc 780 tttgtatgag aatggcatca atggtatcct tgcagatgaa atgggcctag gaaagactct 840 tcaaacaatt tctcttcttg ggtacatgaa acattataga aacattcctg ggcctcatat 900 ggttttggtt cctaagtcta cattacacaa ctggatgagt gaattcaaga gatgggtacc 960 aacacttaga tctgtttgtt tgataggaga taaagaacaa agagctgctt ttgtcagaga 1020 cgttttatta ccgggagaat gggatgtatg tgtaacatct tatgaaatgc ttattaaaga 1080 gaagtctgtg ttcaaaaaat ttaattggag atacttagta atagatgaag ctcacaggat 1140 caaaaatgaa aaatctaagt tgtcagaaat agtgagggaa ttcaagacta caaatagact 1200 attattaact ggaacacctc ttcagaacaa cttgcatgag ctgtggtcac ttcttaactt 1260 tctgttgcca gatgtgttta attcagcaga tgactttgat tcctggtttg atacaaacaa 1320 ctgccttggg gatcaaaaac tagttgagag gcttcatatg gttttgcgtc cattcctcct 1380 tcgtcgaatt aaggctgatg ttgaaaagag tttgcctcca aagaaggaag taaaaatcta 1440 tgtgggcctc agcaaaatgc aaagggaatg gtatactcgg atattaatga aggatataga 1500 tatactcaac tcagcaggca agatggacaa aatgaggtta ttgaacatcc taatgcagtt 1560 gagaaaatgt tgtaatcatc catatctctt tgatggagca gaacctggtc caccttatac 1620 aacagatatg catctagtaa ccaacagtgg caaaatggtg gttttagaca agctgctccc 1680 taagttaaaa gaacaaggtt cacgagtact aatcttcagt caaatgacaa gggtattgga 1740 cattttggaa gattattgca tgtggagaaa ttatgagtac tgcaggttgg atggtcagac 1800 accccatgat gagagacaag actccatcaa tgcatacaat gaaccaaaca gcacaaagtt 1860 tgttttcatg ttaagcacgc gtgctggtgg tcttggcatc aatcttgcga ctgctgatgt 1920 agtaattttg tatgattctg attggaatcc ccaagtagat cttcaggcta tggaccgagc 1980 acatagaatt gggcagacta agacagtcag agtgttccgc tttataactg ataacactgt 2040 agaagaaaga atagtagaac gtgctgagat gaaactcaga ctggattcaa tagtcattca 2100 acaagggagg cttgtggatc agaatctgaa caaaattggg aaagatgaaa tgcttcaaat 2160 gattagacat ggagcaacac atgtgtttgc ttcaaaggaa agtgagatca ctgatgaaga 2220 tatcgatggt attttggaaa gaggtgcaaa gaagactgca gagatgaatg aaaagctctc 2280 caagatgggc gaaagttcac ttagaaactt tacaatggat acagagtcaa gtgtttataa 2340 cttcgaagga gaagactata gagaaaaaca aaagattgca ttcacagagt ggattgaacc 2400 acctaaacga gaaagaaaag ccaactatgc cgttgatgca tatttcaggg aagctcttcg 2460 tgttagtgaa cctaaagcac ccaaggctcc tcgacctcca aaacaaccca atgttcagga 2520 tttccagttc tttcctccac gtttatttga attactggaa aaagaaattc tgttttacag 2580 aaaaactatt gggtacaagg tacctcgaaa tcctgagctg cctaacgcag cacaggcaca 2640 aaaagaagaa cagcttaaaa ttgatgaagc tgaatccctt aatgatgaag agttagagga 2700 aaaagagaag cttctaacac agggatttac caattggaat aagagagatt ttaaccagtt 2760 tatcaaagct aatgagaagt ggggtcgtga tgatattgaa aatatagcaa gagaagtaga 2820 aggcaaaact ccagaagaag tcattgaata ttcagctgtg ttttgggaaa ggtgcaacga 2880 gctccaggac atagagaaga ttatggctca gattgaaagg ggagaggcga gaattcaaag 2940 aagaataagc atcaagaaag cacttgacac aaagattgga cggtacaaag caccttttca 3000 tcagctgaga atatcatatg gtactaacaa aggaaaaaac tatactgaag aagaagatcg 3060 ttttctgatt tgtatgcttc acaaacttgg atttgacaaa gaaaatgttt atgatgaatt 3120 gcgacagtgt attcgcaact ctcctcagtt cagatttgac tggtttctta agtccagaac 3180 tgcaatggag ctccagagga gatgtaatac cttaattact ttgattgaaa gagaaaacat 3240 ggaactagaa gaaaaggaga aggcagagaa aaagaaacga ggaccaaagc cttcaacaca 3300 gaaacgtaaa atggatggcg cacctgatgg tcgaggaaga aaaaagaagc tgaaactatg 3360 aatatgtttt tgtttcataa tcactaactt taaaccagta gttctttaat ttacgggtct 3420 tcataagatg tactgtacaa tgctcaattg ttatgtcatt taaagacatc aggttcatct 3480 gtttactgag ctagaaacat agtatgtagt ttcacttttt taaatgcaac agctgtgctg 3540 aaattttttt atcattaaca cttgaagtaa taaaataggc ttcatttatt aaaaaaaaaa 3600 aaaaaa 3606 <210> 124 <211> 2751 <212> DNA <213> HUMAN <400> 124 atggcggaag gtggaggctg ccgtgagcga ccggatgcgg agactcagaa gtccgagctt 60 ggacccttaa tgaggaccac actccaacgc ggggcgcagt ggtatcttat tgacagccgg 120 tggttcaagc agtggaagaa gtatgtgggc tttgacagct gggacatgta caatgtgggt 180 gaacataacc tatttcctgg cccaatagac aactctgggc tattttcaga tcctgagagt 240 cagaccttga aagaacactt aattgatgaa ttggactatg tattggtccc taccgaggcg 300 tggaataaac tactaaactg gtacggctgt gtagaaggcc agcaacccat cgtcagaaaa 360 gttgtggagc atggcctgtt tgtcaagcac tgcaaagtcg aggtgtattt gctggaactg 420 aagctctgtg agaacagtga ccccaccaat gtgctgagtt gccatttcag caaggcagac 480 accattgcaa ccatcgagaa agagatgcgg aagctattca acatccctgc ggagcgtgaa 540 acacggctct ggaacaaata catgagcaac acctacgagc agttgagcaa gctagacaac 600 actgtccagg atgctgggct ataccagggt caggtgctag taattgagcc tcaaaatgaa 660 gatggcacat ggcccaggca gaccttgcag tcaaatggat ctggcttttc tgcttcgtat 720 aattgtcagg agccaccatc ctctcatata caacctgggc tctgtggact tggaaacctg 780 ggaaacacct gcttcatgaa ctccgctttg cagtgtttga gcaacactgc accactgact 840 gactactttc tcaaagatga gtatgaagcc gaaatcaaca gagacaaccc tctggggatg 900 aaaggggaaa ttgcagaagc ctatgctgaa ctcattaagc agatgtggtc tggaagggac 960 gcccatgtgg cacctcgcat gttcaaaact caagtaggac gttttgctcc tcaattttct 1020 ggctaccagc aacaagattc tcaggagctg ctggcctttc ttctagatgg attgcatgaa 1080 gatctgaacc gggtaaagaa aaagccctac ttggagctga aggatgccaa tgggcggcca 1140 gatgcggtgg tggcaaagga agcctgggag aatcacaggt tgaggaatga ttctgtgatt 1200 gtggatactt tccatggcct cttcaaatct actttggttt gcccagaatg tgctaaggtt 1260 tctgtgacct ttgacccatt ttgctatcta acgctgccac tgcccttgaa gaaagatcga 1320 gttatggagg ttttcctggt tcctgctgac cctcactgca gacctactca gtaccgtgtg 1380 actgtgccgc tgatgggggc tgtgtccgac ctgtgcgagg ctctctccag gctgtctggc 1440 attgctgcag aaaatatggt ggtcgcagat gtgtataatc accgattcca caaaattttc 1500 caaatggatg aaggtttaaa ccacatcatg cctcgggatg acattttcgt gtacgaggtc 1560 tgcagcactt ccgtggatgg ctcggaatgt gtcacgcttc cagtctactt cagggagagg 1620 aagtccaggc catcaagcac ttcctccgca tcagcgctat atgggcagcc actattgctt 1680 tctgtcccca agcacaagtt aacccttgag tctttgtacc aggctgtttg tgatcgtatc 1740 agccgctatg tgaaacagcc tttacctgat gagtttggca gctcaccctt ggagccaggg 1800 gcctgcaatg gctccaggaa cagctgtgaa ggagaagatg aggaagaaat ggagcatcag 1860 gaagaaggca aagagcagct ttcagaaaca gaaggcagtg gggaagatga gccaggaaat 1920 gaccccagtg agaccaccca aaagaagatc aaaggccagc cctgcccaaa aaggcttttt 1980 accttcagtc ttgtgaactc ctatggaaca gctgacataa attcacttgc agctgatgga 2040 aaactactta aactcaactc tcgatctaca ctggccatgg attgggacag tgaaactcgg 2100 agactttact atgatgagca agaatctgag gcctacgaga agcatgtgag catgttgcag 2160 cctcagaaga agaagaagac cacagtggcc ctgagagact gcatcgagct cttcaccacc 2220 atggagaccc ttggggagca tgacccctgg tactgtccca actgtaagaa gcatcaacag 2280 gccacaaaaa agtttgacct atggtccttg cccaagatcc tggtggtcca cctcaaacgt 2340 ttctcctaca acagatactg gagggataag ctcgacacag tcgtagaatt cccaatcaga 2400 gggctgaaca tgtccgagtt tgtctgtaac ctgtcagcaa ggccttatgt gtacgacctc 2460 attgccgtgt ccaatcatta tggagccatg ggggttggcc actacactgc atatgcgaag 2520 aacaaactga atggtaaatg gtattacttt gatgatagca acgtgtccct ggcctctgag 2580 gatcagatag tgactaaagc agcttatgtg ctattttacc aacgtcgaga tgatgaattt 2640 tataagacac cttcacttag cagttctggt tcctctgatg gagggacacg accaagcagc 2700 tctcagcagg gctttgggga tgatgaggct tgcagcatgg acaccaacta a 2751 <210> 125 <211> 1710 <212> DNA <213> HUMAN <400> 125 ccgcggcggc ggagaagcag ctcgccagcc agcagcccgc cagccgccgg gaggttcgat 60 acaagaggct gttttcctag cgtggcttgc tgcctttggt aagaacatgt cgtccatctt 120 gccattcacg ccgccagttg tgaagagact gctgggatgg aagaagtcag ctggtgggtc 180 tggaggagca ggcggaggag agcagaatgg gcaggaagaa aagtggtgtg agaaagcagt 240 gaaaagtctg gtgaagaagc taaagaaaac aggacgatta gatgagcttg agaaagccat 300 caccactcaa aactgtaata ctaaatgtgt taccatacca agcacttgct ctgaaatttg 360 gggactgagt acaccaaata cgatagatca gtgggataca acaggccttt acagcttctc 420 tgaacaaacc aggtctcttg atggtcgtct ccaggtatcc catcgaaaag gattgccaca 480 tgttatatat tgccgattat ggcgctggcc tgatcttcac agtcatcatg aactcaaggc 540 aattgaaaac tgcgaatatg cttttaatct taaaaaggat gaagtatgtg taaaccctta 600 ccactatcag agagttgaga caccagtttt gcctccagta ttagtgcccc gacacaccga 660 gatcctaaca gaacttccgc ctctggatga ctatactcac tccattccag aaaacactaa 720 cttcccagca ggaattgagc cacagagtaa ttatattcca gaaacgccac ctcctggata 780 tatcagtgaa gatggagaaa caagtgacca acagttgaat caaagtatgg acacaggctc 840 tccagcagaa ctatctccta ctactctttc ccctgttaat catagcttgg atttacagcc 900 agttacttac tcagaacctg cattttggtg ttcaatagca tattatgaat taaatcagag 960 ggttggagaa accttccatg catcacagcc ctcactcact gtagatggct ttacagaccc 1020 atcaaattca gagaggttct gcttaggttt actctccaat gttaaccgaa atgccacggt 1080 agaaatgaca agaaggcata taggaagagg agtgcgctta tactacatag gtggggaagt 1140 ttttgctgag tgcctaagtg atagtgcaat ctttgtgcag agccccaatt gtaatcagag 1200 atatggctgg caccctgcaa cagtgtgtaa aattccacca ggctgtaatc tgaagatctt 1260 caacaaccag gaatttgctg ctcttctggc tcagtctgtt aatcagggtt ttgaagccgt 1320 ctatcagcta actagaatgt gcaccataag aatgagtttt gtgaaagggt ggggagcaga 1380 ataccgaagg cagacggtaa caagtactcc ttgctggatt gaacttcatc tgaatggacc 1440 tctacagtgg ttggacaaag tattaactca gatgggatcc ccttcagtgc gttgctcaag 1500 catgtcataa agcttcacca atcaagtccc atgaaaagac ttaatgtaac aactcttctg 1560 tcatagcatt gtgtgtggtc cctatggact gtttactatc caaaagttca agagagaaaa 1620 cagcacttga ggtctcatca attaaagcac cttgtggaat ctgtttccta tatttgaata 1680 ttagatggga aaattagtgt cataaagatc 1710 <210> 126 <211> 1568 <212> DNA <213> HUMAN <400> 126 cgtccttcct cagccgcggg tgatcgtagc tcggaaatgg cgggatttgg tgctatggag 60 aaatttttgg tagaatataa gagtgcagtg gagaagaaac tggcagagta caaatgtaac 120 accaacacag caattgaact aaaattagtt cgttttcctg aagatcttga aaatgacatt 180 agaactttct ttcctgagta tacccatcaa ctctttgggg atgatgaaac tgcttttggt 240 tacaagggtc taaagatcct gttatactat attgctggta gcctgtcaac aatgttccgt 300 gttgaatatg catctaaagt tgatgagaac tttgactgtg tagaggcaga tgatgttgag 360 ggcaaaatta gacaaatcat tccacctgga ttttgcacaa acacgaatga tttcctttct 420 ttactggaaa aggaagttga tttcaagcca ttcggaacct tacttcatac ctactcagtt 480 ctcagtccaa caggaggaga aaactttacc tttcagatat ataaggctga catgacatgt 540 agaggctttc gagaatatca tgaaaggctt cagacctttt tgatgtggtt tattgaaact 600 gctagcttta ttgacgtgga tgatgaaaga tggcactact ttctagtatt tgagaagtat 660 aataaggatg gagctacgct ctttgcgacc gtaggctaca tgacagtcta taattactat 720 gtgtacccag acaaaacccg gccacgtgta agtcagatgc tgattttgac tccatttcaa 780 ggtcaaggcc atggtgctca acttcttgaa acagttcata gatactacac tgaatttcct 840 acagttcttg atattacagc ggaagatcca tccaaaagct atgtgaaatt acgagacttt 900 gtgcttgtga agctttgtca agatttgccc tgtttttccc gggaaaaatt aatgcaagga 960 ttcaatgaag atatggcgat agaggcacaa cagaagttca aaataaataa gcaacacgct 1020 agaagggttt atgaaattct tcgactactg gtaactgaca tgagtgatgc cgaacaatac 1080 agaagctaca gactggatat taaaagaaga ctaattagcc catataagaa aaagcagaga 1140 gatcttgcta agatgagaaa atgtctcaga ccagaagaac tgacaaacca gatgaaccaa 1200 atagaaataa gcatgcaaca tgaacagctg gaagagagtt ttcaggaact agtggaagat 1260 taccggcgtg ttattgaacg acttgctcaa gagtaaagat tatactgctc tgtacaggaa 1320 gcttgcaaat tttctgtaca atgtgctgtg aaaaatctga tgactttaat tttaaaatct 1380 tgtgacattt tgcttatact aaaagttatc tatctttagt tgaatatttt cttttggaga 1440 gattgtatat tttaaaatac tgtttagagt ttatgagcat atattgcatt taaagaaaga 1500 taaagcttct gaaatactac tgcaattgct tcccttctta aacagtataa taaatgctta 1560 gttgtgat 1568 <210> 127 <211> 459 <212> DNA <213> HUMAN <400> 127 atggcgagca tgcgagtggt gaaggagctg gaggatcttc agaagaagcc tcccccatac 60 ctgcggaacc tgtccagcga tgatgccaat gtcctggtgt ggcacgctct cctcctaccc 120 gaccaacctc cctaccacct gaaagccttc aacctgcgca tcagcttccc gccggagtat 180 ccgttcaagc ctcccatgat caaattcaca accaagatct accaccccaa cgtggacgag 240 aacggacaga tttgcctgcc catcatcagc agtgagaact ggaagccttg caccaagact 300 tgccaagtcc tggaggccct caatgtgctg gtgaatagac cgaatatcag ggagcccctg 360 cggatggacc tcgctgacct gctgacacag aatccggagc tgttcagaaa gaatgccgaa 420 gagttcaccc tccgattcgg agtggaccgg ccctcctaa 459 <210> 128 <211> 2377 <212> DNA <213> HUMAN <400> 128 ggtgacaaag agccaacaga gacaatagga gacttgtcaa tttgtcttga tgggctacag 60 ttagagtctg aagttgttac caatggtgaa actacatgtt cagaaagtgc ttctcagaat 120 gatgatggct ccagatccaa ggatgaaaca agagtgagca caaatggatc agatgaccct 180 gaagatgcag gagctggtga aaataggaga gtcagtggga ataattctcc atcactctca 240 aatggtggtt ttaaaccttc tagacctcca agaccttcac gaccaccacc acccacccca 300 cgtagaccag catctgtcaa tggttcacca tctgccactt ctgaaagtga tgggtctagt 360 acaggctctc tgccgccgac aaatacaaat acaaatacat ctgaaggagc aacatctgga 420 ttaataattc ctcttactat atctggaggc tcaggcccta ggccattaaa tcctgtaact 480 caagctccct tgccacctgg ttgggagcag agagtggacc agcacgggcg agtttactat 540 gtagatcatg ttgagaaaag aacaacatgg gatagaccag aacctctacc tcctggctgg 600 gaacggcggg ttgacaacat gggacgtatt tattatgttg accatttcac aagaacaaca 660 acgtggcaga ggccaacact ggaatccgtc cggaactatg aacaatggca gctacagcgt 720 agtcagcttc aaggagcaat gcagcagttt aaccagagat tcatttatgg gaatcaagat 780 ttatttgcta catcacaaag taaagaattt gatcctcttg gtccattgcc acctggatgg 840 gagaagagaa cagacagcaa tggcagagta tatttcgtca accacaacac acgaattaca 900 caatgggaag accccagaag tcaaggtcaa ttaaatgaaa agcccttacc tgaaggttgg 960 gaaatgagat tcacagtgga tggaattcca tattttgtgg accacaatag aagaactacc 1020 acctatatag atccccgcac aggaaaatct gccctagaca atggacctca gatagcctat 1080 gttcgggact tcaaagcaaa ggttcagtat ttccggttct ggtgtcagca actggccatg 1140 ccacagcaca taaagattac agtgacaaga aaaacattgt ttgaggattc ctttcaacag 1200 ataatgagct tcagtcccca agatctgcga agacgtttgt gggtgatttt tccaggagaa 1260 gaaggtttag attatggagg tgtagcaaga gaatggttct ttcttttgtc acatgaagtg 1320 ttgaacccaa tgtattgcct gtttgaatat gcagggaagg ataactactg cttgcagata 1380 aaccccgctt cttacatcaa tccagatcac ctgaaatatt ttcgttttat tggcagattt 1440 attgccatgg ctctgttcca tgggaaattc atagacacgg gtttttcttt accattctat 1500 aagcgtatct tgaacaaacc agttggactc aaggatttag aatctattga tccagaattt 1560 tacaattctc tcatctgggt taaggaaaac aatattgagg aatgtgattt ggaaatgtac 1620 ttctccgttg acaaagaaat tctaggtgaa attaagagtc atgatctgaa acctaatggt 1680 ggcaatattc ttgtaacaga agaaaataaa gaggaataca tcagaatggt agctgagtgg 1740 aggttgtctc gaggtgttga agaacagaca caagctttct ttgaaggctt taatgaaatt 1800 cttccccagc aatatttgca atactttgat gcaaaggaat tagaggtcct tttatgtgga 1860 atgcaagaga ttgatttgaa tgactggcaa agacatgcca tctaccgtca ttatgcaagg 1920 accagcaaac aaatcatgtg gttttggcag tttgttaaag aaattgataa tgagaagaga 1980 atgagacttc tgcagtttgt tactggaacc tgccgattgc cagtaggagg atttgctgat 2040 ctcatgggga gcaatggacc acagaaattc tgcattgaaa aagttgggaa agaaaattgg 2100 ctacccagaa gtcatacctg ttttaatcgc ctggacctgc caccatacaa gagctatgag 2160 caactgaagg aaaagctgtt gtttgccata gaagaaacag aaggatttgg acaagagtaa 2220 cttctgagaa cttgcaccat gaatgggcaa gaacttattt gcaatgtttg tccttctctg 2280 cctgttgcac atcttgtaaa attggacaat ggctctttag agagttatct gagtgtaagt 2340 aaattaatgt tctcatttaa aaaaaaaaaa aaaaaaa 2377 <210> 129 <211> 3525 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(3525) <223> N=any base <400> 129 ggcacgaggc atggcgctga ggggccgccc cgcgggaaga tgaataaggg ctggctggag 60 ctggagagcg acccaggcct cttcaccctg ctcgtggaag atttcggtgt caagggggtg 120 caagtggagg agatctacga ccttcagagc aaatgtcagg gccctgtata tggatttatc 180 ttcctgttca aatggatcga agagcgccgg tcccggcgaa aggtctctac cttggtggat 240 gatacgtccg tgattgatga tgatattgtg aataacatgt tctttgccca ccagctgata 300 cccaactctt gtgcaactca tgccttgctg agcgtgctcc tgaactgcag cagcgtggac 360 ctgggaccca ccctgagtcg catgaaggac ttcaccaagg gtttcagccc tgagagcaaa 420 ggatatgcga ttggcaatgc cccggagttg gccaaggccc ataatagcca tgccaggccc 480 gagccacgcc acctccctga gaagcagaat ggccttagtg cagtgcggac catggaggcg 540 ttccactttg tcagctatgt gcctatcaca ggccggctct ttgagctgga tgggctgaag 600 gtctacccca ttgaccatgg gccctggggg gaggacgagg agtggacaga caaggcccgg 660 cgggtcatca tggagcgtat cggcctcgcc actgcagggg agccctacca cgacatccgc 720 ttcaacctga tggcagtggt gcccgaccgc aggatcaagt atgaggccag gctgcatgtg 780 ctgaaggtga accgtcagac agtactagag gctctgcagc agctgataag agtaacacag 840 ccagagctga ttcagaccca caagtctcaa gagtcacagc tgcctgagga gtccaagtca 900 gccagcaaca agtccccgct ggtgctggaa gcaaacaggg cccctgcagc ctctgagggc 960 aaccacacag atggtgcaga ggaggcggct ggttcatgcg cacaagcccc atcccacagc 1020 cctcccaaca aacccaagct agtggtgaag cctccaggca gcagcctcaa tggggttcac 1080 cccaacccca ctcccattgt ccagcggctg ccggcctttc tagacaatca caattatgcc 1140 aagtccccca tgcaggagga agaagacctg gcggcaggtg tgggccgcag ccgagttcca 1200 gtccgcccac cccagcagta ctcagatgat gaggatgact atgaggatga cgaggaggat 1260 gacgtgcaga acaccaactc tgcccttagg tataagggga agggaacagg gaagccaggg 1320 gcattgagcg gttctgctga tgggcaactg tcagtgctgc agcccaacac catcaacgtc 1380 ttggctgaga agctcaaaga gtcccagaag gacctctcaa ttcctctgtc catcaagact 1440 agcagcgggg ctgggagtcc ggctgtggca gtgcccacac actcgcagcc ctcacccacc 1500 cccagcaatg agagtacaga cacggcctct gagatcggca gtgctttcaa ctcgccactg 1560 cgctcgccta tccgctcagc caacccgacg cggccctcca gccctgtcac ctcccacatc 1620 tccaaggtgc tttttggaga ggatgacagc ctgctgcgtg ttgactgcat acgctacaac 1680 cgtgctgtcc gtgatctggg tcctgtcatc agcacaggcc tgctgcacct ggctgaggat 1740 ggggtgctga gtcccctggc gctgacagag ggtgggaagg gttcctcgcc ctccatcaga 1800 ccaatccaag gcagccaggg gtccagcagc ccagtggaga aggaggtcgt ggaagccacg 1860 gacagcagag agaagacggg gatggtgagg cctggcgagc ccttgagtgg ggagaaatac 1920 tcacccaagg agctgctggc actgctgaag tgtgtggagg ctgagattgc aaactatgag 1980 gcgtgcctca aggaggaggt agagaagagg aagaagttca agattgatga ccagagaagg 2040 acccacaact acgatgagtt catctgcacc tttatctcca tgctggctca ggaaggcatg 2100 ctggccaacc tagtggagca gaacatctcc gtgcggcggc gccaaggggt cagcatcggc 2160 cggctccaca agcagcggaa gcctgaccgg cggaaacgct ctcgccccta caaggccaag 2220 cgccagtgag gactgctggc cctgactctg cagcccactc ttgccgtgtg gccctcacca 2280 gggtccttcc ctgccccact tccccttttc ccagtattac tgaatagtcc cagctggaga 2340 gtccaggccc tgggaatggg aggaaccagg ccacattcct tccatcgtgc cctgaggcct 2400 gacacggcag atcagcccca tagtgctcag gaggcagcat ctggagttgg ggcacagcga 2460 ggtactgcag cttcctccac agccggctgt ggagcagcag gacctggccc ttctgcctgg 2520 gcagcagaat atatatttta cctatcagag acatctattt ttctgggctc caacccaaca 2580 tgccaccatg ttgacataag ttcctacctg actatgcttt ctctcctagg agctgtcctg 2640 gtgggcccag gtccttgtat catnccacgg tcccaactac agggtcctag ctgggggcct 2700 gggtgggccc tgggctctgg gccctgctgc tctagcccca gccaccagcc tgtccctgtt 2760 gtaaggaagc caggtcttct ctcttcattc ctcttaggag agtgccaaac tcagggaccc 2820 agcactgggc tgggttggga gtagggtgtc ccagtggggt tggggtgagc aggctgctgg 2880 gatcccatgg cctgagcaga gcatgtggga actgttcagt ggcctgtgaa ctgtcttcct 2940 tgttctagcc aggctgttca agactgctct ccatagcaag gttctagggc tcttcgcctt 3000 cagtgttgtg gccctagcta tgggcctaaa ttgggctcta ggtctctgtc cctggcgctt 3060 gaggctcaga agagcctctg tccagcccct cagtattacc atgtctccct ctcaggggta 3120 gcagagacag ggttgcttat aggaagctgg caccactcag ctcttcctgc tactccagtt 3180 tcctcagcct ctgcaaggca ctcagggtgg gggacagcag gatcaagaca acccgttgga 3240 gcccctgtgt tccagaggac ctgatgccaa ggggtaatgg gcccagcagt gcctctggag 3300 cccaggcccc aacacagccc catggcctct nccagatggc tttgnaaaag gtgatccaan 3360 caggcccctt tatctgtaca tagtgactga gtggggggtg ctggcaagtg tggcanctnc 3420 ctctgggctg agcacagctt gacccctcta gcccctgtaa anactggatc aatgaatgaa 3480 taaaactctc ctaagnatct cctgagaaaa aaaaaaaaaa aaagg 3525 <210> 130 <211> 2553 <212> DNA <213> HUMAN <400> 130 acgcgtccgg gaaacgttgc ttctgagggg agcccaagat gaccggttct aacgagttca 60 agctgaacca gccacccgag gatggcatct cctccgtgaa gttcagcccc aacacctccc 120 agttcctgct tgtctcctcc tgggacacgt ccgtgcgtct ctacgatgtg ccggccaact 180 ccatgcggct caagtaccag cacaccggcg ccgtcctgga ctgcgccttc tacgatccaa 240 cgcatgcctg gagtggagga ctagatcatc aattgaaaat gcatgatttg aacactgatc 300 aagaaaatct tgttgggacc catgatgccc ctatcagatg tgttgaatac tgtccagaag 360 tgaatgtgat ggtcactgga agttgggatc agacagttaa actgtgggat cccagaactc 420 cttgtaatgc tgggaccttc tctcagcctg aaaaggtata taccctctca gtgtctggag 480 accggctgat tgtgggaaca gcaggccgca gagtgttggt gtgggactta cggaacatgg 540 gttacgtgca gcagcgcagg gagtccagcc tgaaatacca gactcgctgc atacgagcgt 600 ttccaaacaa gcagggttat gtattaagct ctattgaagg ccgagtggca gttgagtatt 660 tggacccaag ccctgaggta cagaagaaga agtatgcctt caaatgtcac agactaaaag 720 aaaataatat tgagcagatt tacccagtca atgccatttc ttttcacaat atccacaata 780 catttgccac aggtggttct gatggctttg taaatatttg ggatccattt aacaaaaagc 840 gactgtgcca attccatcgg taccccacga gcatcgcatc acttgccttc agtaatgatg 900 ggactacgct tgcaatagcg tcatcatata tgtatgaaat ggatgacaca gaacatcctg 960 aagatggtat cttcattcgc caagtgacag atgcagaaac aaaacccaag tcaccatgta 1020 cttgacaaga tttcatttac ttaagtgcca tgttgatgat aataaaacaa ttcgtactcc 1080 ccaatggtgg atttattact attaaagaaa ccagggaaaa tattaatttt aatattataa 1140 caacctgaaa ataatggaaa agaggttttt gaattttttt ttttaaataa acaccttctt 1200 aagtgcatga gatggtttga tggtttgctg cattaaaggt atttgggcaa acaaaattgg 1260 agggcaagtg actgcagttt tgagaatcag ttttgacctt gatgattttt tgtttccact 1320 gtggaaataa atgtttgtaa ataagtgtaa taaaaatccc tttgcattct ttctggacct 1380 taaatggtag aggaaaaggc tcgtgagcca tttgtttctt ttgctggtta tagttgctaa 1440 ttctaaagct gcttcagact gcttcatgag gaggttaatc tacaattaaa caatatttcc 1500 tcttggccgt ccattatttt ctgaagcaga tggttcatca tttcctgggc tgttaaacaa 1560 agcgaggtta aggttagact cttgggaatc agctagtttt caatcttatt agggtgcaga 1620 aggaaaacta ataagaaaac ctcctaatat cattttgtga ctgtaaacaa ttatttatta 1680 gcaaacaatt gatcccagaa gggcaaattg tttgagtcag taatgagctg agaaaagaca 1740 gagcatatct gtgtatttgg aaaaataatt gtaacgtaat tgcagtgcat ttagacaggc 1800 atctatttgg acctgtttct atctctaaat gaatttttgg aaacattaat gaggtttaca 1860 tatttctctg acatttatat agttcttatg tccatttcag ttgaccagcc gctggtgatt 1920 aaagttaaaa agaaaaaaat tatagtgaga atgagattca tttcaatgta atgcactaaa 1980 gcagaacacg aacttagctt ggcctattct aggtagttcc aaatagtatt tttgttgtca 2040 aactttaaaa tttatattaa tttgcaaatg tatgtctctg agtaggactt ggacctttcc 2100 tgagatttat tttatccgtg atgtattttt tttaattctt ttgatacaga gaagggtctt 2160 tttttttttt ttaagtattt cagtgaaaac ttggtgtaag tctgaaccca tcttttgaaa 2220 tgtattttct tcattgcagg tccacctaat catcctgtga aagtggtttc tctatggaaa 2280 gctttgtttg cttcctacaa atacatgctt attccttaag ggatgtgtta gagttactgt 2340 ggatttctct gttttctgtc ttacaagaaa cttgtctatg taccttaata ctttgtttag 2400 gatgaggagt ctttgtgtcc ctgtacagta gtctgacgta tttccccttc tgtcccctag 2460 taagcccagt tgctgtatct gaacagtttg agctcttttt gtaatatact ctaaacctgt 2520 tatttctgtg ctaataaacg agatgcagaa ccc 2553 <210> 131 <211> 1125 <212> DNA <213> HUMAN <400> 131 cccccatgtg acagtgacgg ggtccccgct ccaggagacg ctcgagtctg cgtcccggcc 60 ctcagcactg tccactgttt cggtgccagc agagaccagc aggcccggga cagttggtgt 120 ttggccgtgc cgctgtctaa cttggtgtgc agagtgaatt gccgctgccg gagcggagag 180 aggcggagcg gccaggagag aggggatttc tgtcagcgcc ggcctcggga gctcggagac 240 atgaacggct tcacgcctga cgagatgagc cgcggcgggg atgcggccgc cgcagtggcc 300 gcagtggtcg ctgccgcggc cgccgccgcc tcggcgggga acgggaccgg cgcgggcacc 360 ggggctgagg tgccgggcgc gggggcggtc tcagcggctg ggcccccggg ggcggccggg 420 ccgggccccg ggcaactgtg ctgcctgcgg gaggatggtg agcggtgcgg ccgggcggca 480 ggcaacgcca gcttcagcaa gaggatccag aagagcatct cccagaagaa ggtgaagatc 540 gagctggata agagcgcaag gcatctttac atatgtgatt atcataaaaa cttaattcag 600 agtgttcgaa acagaagaaa gagaaaaggg agtgatgatg atggaggtga ttcacctgtt 660 caagatattg ataccccaga ggttgattta taccaattac aagtaaatac acttaggaga 720 tacaaaagac acttcaagct accaaccaga ccaggactta ataaagcaca acttgttgag 780 atagttggtt gccactttag gtctattcca gtgaatgaaa aagacacctt aacatatttc 840 atctactcag tgaagaatga caagaacaaa tcagatctca aggttgatag tggtgttcac 900 taggagacgt ggaattgaga ctaataactt ggatgttaac actgtttact gttttttcac 960 atgtagaaat gttctttgtg tattttttct acagaggatt ttctctgatt ttattttctt 1020 tgtttctgac tctaataatt agttggaaac tcatataaaa tgagctttcc taaattaaat 1080 ctattttaaa taaaggttat tactattaaa aaaaaaaaaa aaaaa 1125 <210> 132 <211> 751 <212> DNA <213> HUMAN <400> 132 aggatgatca agctgttctc gctgaagcag cagaagaagg aggaggagtc ggcgggcggc 60 accaagggca gcagcaagaa ggcgtcggcg gcgcagctgc ggatccagaa ggacataaac 120 gagctgaacc tgcccaagac gtgtgatatc agcttctcag atccagacga cctcctcaac 180 ttcaagctgg tcatctgtcc tgatgagggc ttctacaaga gtgggaagtt tgtgttcagt 240 tttaaggtgg gccagggtta cccgcatgat ccccccaagg tgaagtgtga gacaatggtc 300 tatcacccca acattgacct cgagggcaac gtctgcctca acatcctcag agaggactgg 360 aagccagtcc ttacgataaa ctccataatt tatggcctgc agtatctctt cttggagccc 420 aaccccgagg acccactgaa caaggaggcc gcagaggtcc tgcagaacaa ccggcggctg 480 tttgagcaga acgtgcagcg ctccatgcgg ggtggctaca tcggctccac ctactttgag 540 cgctgcctga aatagggttg gcgcataccc acccgccgcc acggccacaa gccctggcat 600 cccctgcaaa tatttattgg gggccatggg taggggtttg gggggcggcc ggtgggggaa 660 tcccctgcct tggccttgcc tccccttcct gccacgtgcc cctagttatt ttttttttaa 720 caccaggcta actaaagggg aatgttactg c 751 <210> 133 <211> 2845 <212> DNA <213> HUMAN <400> 133 agcaccaaat ccaagatggc ggccagcagg aggctgatga aggagcttga agaaatccgc 60 aaatgtggga tgaaaaactt ccgtaacatc caggttgatg aagctaattt attgacttgg 120 caagggctta ttgttcctga caaccctcca tatgataagg gagccttcag aatcgaaatc 180 aactttccag cagagtaccc attcaaacca ccgaagatca catttaaaac aaagatctat 240 cacccaaaca tcgacgaaaa ggggcaggtc tgtctgccag taattagtgc cgaaaactgg 300 aagccagcaa ccaaaaccga ccaagtaatc cagtccctca tagcactggt gaatgacccc 360 cagcctgagc acccgcttcg ggctgaccta gctgaagaat actctaagga ccgtaaaaaa 420 ttctgtaaga atgctgaaga gtttacaaag aaatatgggg aaaagcgacc tgtggactaa 480 aatctgccac gattggttcc agcaagtgtg agcagagacc ccgtgcagtg cattcagaca 540 ccccgcaaag caggactctg tggaaattga cacgtgccac cgcctggcgt tcgcttgtgg 600 cagttactaa ctttctacag ttttcttaat caaaagtggt ctaggtaacc tgtaaagaaa 660 ggattaaaaa tttaagatgt tctagttctg ctctctttgt tttaaaaatc actgcttcaa 720 tctacttcaa aagaatggtg tttcttttct tgtccaattt tatccaaaat cttcaagtta 780 catttaaccc ataaggttta aaaaaaagga aaaaaaacgg ttgtggttcc ctttcttccc 840 tacccttgcc actcccactt tctggcaccg agtttatttt tcacttactt acttccccag 900 accccgggct cgcctccaca aaggagaaga gactgccctg gcggtcctgg tggcttttct 960 tagcatgtgt ggcactgttg cccagtgtgg gagttggttt aaattctcct gactccagtt 1020 tataacatcc ttttaaaaaa tttaaaaaca aacagccaca cccctcctcc agtccttctc 1080 ctcagttctt gtgtgaaact ccagctgatg ttaccacagt aacatcagtt aattgggcaa 1140 gccctgatgt cagtgtgtgt aactgacctc tggcctggcc tgcacagaga agccctataa 1200 tcacaggtct gtggtggccc cgaaatgggg ggcctgctag tcaggaggat gctgtgcaca 1260 ctgtgtgtga tgaatctcgc cagaaaggct cctgaggtcc caggttggca cttctccctg 1320 cagccattgt agaagatctg ctggtccttg caggcaaagc tacagccaga atgtccgttt 1380 gaaactccta gctcatctgt caccgagctt catccgaatg tgccacggag cttgctctcc 1440 acttcctccg tgcagtggcc ctgccacagc cctccctcgg cacactttga ccctttgtag 1500 gattggaatt agcaggactc ggctatttaa agcaccagtc tggggtcgcc tgggcccctg 1560 ctgaccccct cctccagagc agccagccca gcccgggaac aagacggact tcctctccct 1620 tcggactcac agcctttgca gagtcaagct ccacttgaag ctcactcagt aatatccttt 1680 caatgtgttt tatattgttt tgactgcctt tttttgtaga aataaaaatt gaccttagaa 1740 tttatcgtca gataaacttg taaagatttg aatattaatg tcttttcaag gcaaatggga 1800 ttgtccccgc actagtagag aatccatgtc gctctgacac cccaaggaag ccgacgatcc 1860 aaatgccgtg tgtcaccaac cccgcttctg ccactggcgg cttcccttct tggctcttgg 1920 gggggactag atcctgtgga gaagatgact taaactttgc tttttgtttt aattttaatt 1980 ctataacttg agatctttcc ggggcctaca ggcgtgtaag acagcttggt ctggtctgtg 2040 cagaagtggg gagtgatggg caggttcggc agcctaacat tgttcaggcg catggcccct 2100 gcggtgtgta cacgaactcg gcttcttttg tcctaggtac gccaagggca ggtttctgga 2160 gactcccttg tgcccgggat ggcaagggca ccgggctggc gtttccacat ctgtcttcat 2220 tagcagaaaa gtgatgatgg attttatttc actcacactc cagtttgtaa taaaatgcca 2280 aattctgtca gctatccaaa caagccacca tttgttcttg ttgcttctct ggatccagaa 2340 atgttgccat tcttggaaac tgtcccattg cttcgtattt ctgccaacgt agctctgcct 2400 gcctgtcaac ccctcactgc actctgctca tcacgggagg atacctgtgt gccggcagcc 2460 cctcagggac tctcagccct ggcactggca ccccagggtt ggccccgtca gcagaggctt 2520 ggctttcgag ccagtgggtg tctctccttt gggcctgggc ggcttgctcc tgccagccat 2580 gccttcaggg taggctctga gcaagctggc gaacagccct ggctgctcca aaaccaaaaa 2640 gctgggtcct ctggaggagg ggcgagctgt ggagcagcca cccactgctg ccccaagctc 2700 actcaggaat tcacacccgc ctggtttctt gaagtgtgct gggtccttcc ctctgctccc 2760 tactccccac cacggcagag aataggcttt ctaagatgct gcgatcccgt tctgctgccc 2820 gtaataaaaa tgctctcaga cactg 2845 <210> 134 <211> 2816 <212> DNA <213> HUMAN <400> 134 atggtatttt acttttttgg gaaatacttg gaaatgaaga cctgcaactg taatttgaaa 60 taaggaaaac tttaattttc agtataaaaa ttgctcaaat agaattgcct gattttaatg 120 acaaaagtat atgggagtcc acatttatgt aagaaatgaa actataaaat gtataaataa 180 tttgcaaatc agaattgctg tcgaaagttt tactataatg aaagatattt tcatactctc 240 aaaaatatag aggaaagggg ccaagattat agtaccagtc acaatctttt gatgaggacg 300 aaatgaatca ggtaacagac tgggttgacc catcatttga tgattttcta gagtgtagtg 360 gcgtctctac tattactgcc acatcattag gtgtgaataa ctcaagtcat agaagaaaaa 420 atgggccttc tacattagaa agcagcagat ttccagcgag aaaaagagga aatctatctt 480 ccttagaaca gatttatggt ttagaaaatt caaaagaata tctgtctgaa aatgaaccat 540 gggtggataa atataaacca gaaactcagc atgaacttgc tgtgcataaa aagaaaattg 600 aagaagtcga aacctggtta aaagctcaag ttttagaaag gcaaccaaaa cagggtggat 660 ctattttatt aataacaggt cctcctggat gtggaaagac aacgacctta aaaatactat 720 caaaggagca tggtattcaa gtacaagagt ggattaatcc agttttacca gacttccaaa 780 aagatgattt caaggggatg tttaatactg aatcaagctt ccatatgttt ccctatcagt 840 ctcagatagc agttttcaaa gagtttctac taagagcgac aaagtataac aagttacaaa 900 tgcttggaga tgatctgaga actgataaga agataattct ggttgaagat ttacctaacc 960 agttttatcg ggattctcat actttacatg aagttctaag gaagtatgtg aggattggtc 1020 gatgtcctct tatatttata atctcggaca gtctcagtgg agataataat caaaggttat 1080 tgtttcccaa agaaattcag gaagagtgtt ctatctcaaa tattagtttc aaccctgtgg 1140 caccaacaat tatgatgaaa tttcttaatc gaatagtgac tatagaagct aacaagaatg 1200 gaggaaaaat tactgtccct gacaaaactt ctctagagtt gctctgtcag ggatgttctg 1260 gtgatatcag aagtgcaata aacagcctcc agttttcttc ttcaaaagga gaaaacaact 1320 tacggccaag gaaaaaagga atgtctttaa aatcagatgc tgtgctgtca aaatcaaaac 1380 gaagaaaaaa acctgatagg gtttttgaaa atcaagaggt ccaagctatt ggtggcaaag 1440 atgtttctct gtttctcttc agagctttgg ggaaaattct atattgtaaa agagcatctt 1500 taacagaatt agactcacct cggttgccct ctcatttatc agaatatgaa cgggatacat 1560 tacttgttga acctgaggag gtagtagaaa tgtcacacat gcctggagac ttatttaatt 1620 tatatcttca ccaaaactac atagatttct tcatggaaat tgatgatatt gtgagagcca 1680 gtgaatttct gagttttgca gatatcctca gtggtgactg gaatacacgc tctttactca 1740 gggaatatag cacatctata gctacgagag gtgtgatgca ttccaacaaa gcccgaggat 1800 atgctcattg ccaaggagga ggatcaagtt ttcgaccctt gcacaaacct cagtggtttc 1860 taataaataa aaagtatcgg gaaaattgcc tggcagcaaa agcacttttt cctgacttct 1920 gcctaccagc tttatgcctc caaactcagc tattgccata ccttgctcta ctaaccattc 1980 caatgagaaa tcaagctcag atttctttta tccaagatat tggaaggctc cctctgaagc 2040 gacactttgg aagattgaaa atggaagccc tgactgacag ggaacatgga atgatagacc 2100 ctgacagcgg agatgaagcc cagcttaatg gaggacattc tgcagaggaa tctctgggtg 2160 aacccactca agccactgtg ccggaaacct ggtctcttcc tttgagtcag aatagtgcca 2220 gtgaactgcc tgctagccag ccccagccct tttcagccca aggagacatg gaagaaaaca 2280 taataataga agactacgag agtgatggga catagaagcc agcctgctaa tcagattgct 2340 acttcacagc ttcatttttg tttcattcag tggtacttca gcagagttaa tatgcttttc 2400 tgatgaatta cacaacagtt tgttaattct tcattcttgt agtatttcat cacaagaaac 2460 ctactcttct gtcatcttga agtaaataga agatcaagcc ttcaaatctc ttaatttttt 2520 cggtatttat taaatctgtg agtggtttaa ggagcggtca gtgtgtataa agtgtgtttg 2580 aacattatgc caaatatcaa gatgtgaagg actaattcag gatgcaaaaa cgttattggg 2640 gggttgtaaa tatcaactat tcaacagttt aggatgcaat tacgagtgta aactgtgtgc 2700 cttatttaca ctttattgtc tcccgcttct cagatagttt tgatgtgttg tacagtggaa 2760 tatcttagat actttttgga aagtatttac ataagttata tcacaattaa aatgtt 2816 <210> 135 <211> 1386 <212> DNA <213> HUMAN <400> 135 gccccatctc cttgggctgc ccgtgcttcg tgctttggac taccgcccag cagtgtcctg 60 ccctctgcct gggcctcggt ccctcctgca cctgctgcct ggatccccgg cctgcctggg 120 cctgggcctt ggttctcccc atgacaccac ctgaacgtct cttcctccca agggtgtgtg 180 gcaccaccct acacctcctc cttctggggc tgctgctggt tctgctgcct ggggcccagg 240 ggctccctgg tgttggcctc acaccttcag ctgcccagac tgcccgtcag caccccaaga 300 tgcatcttgc ccacagcacc ctcaaacctg ctgctcacct cattggagac cccagcaagc 360 agaactcact gctctggaga gcaaacacgg accgtgcctt cctccaggat ggtttctcct 420 tgagcaacaa ttctctcctg gtccccacca gtggcatcta cttcgtctac tcccaggtgg 480 tcttctctgg gaaagcctac tctcccaagg ccacctcctc cccactctac ctggcccatg 540 aggtccagct cttctcctcc cagtacccct tccatgtgcc tctcctcagc tcccagaaga 600 tggtgtatcc agggctgcag gaaccctggc tgcactcgat gtaccacggg gctgcgttcc 660 agctcaccca gggagaccag ctatccaccc acacagatgg catcccccac ctagtcctca 720 gccctagtac tgtcttcttt ggagccttcg ctctgtagaa cttggaaaaa tccagaaaga 780 aaaaataatt gatttcaaga ccttctcccc attctgcctc cattctgacc atttcagggg 840 tcgtcaccac ctctcctttg gccattccaa cagctcaagt cttccctgat caagtcaccg 900 gagctttcaa agaaggaatt ctaggcatcc caggggacca cacctccctg aaccatccct 960 gatgtctgtc tggctgagga tttcaagcct gcctaggaat tcccagccca aagctgttgg 1020 tctgtcccac cagctaggtg gggcctagat ccacacacag aggaagagca ggcacatgga 1080 ggagcttggg ggatgactag aggcagggag gggactattt atgaaggcaa aaaaattaaa 1140 ttatttattt atggaggatg gagagagggg aataatagaa gaacatccaa ggagaaacag 1200 agacaggccc aagagatgaa gagtgagagg gcatgcgcac aaggctgacc aagagagaaa 1260 gaagtaggca tgagggatca cagggcccca gaaggcaggg aaaggctctg aaagccagct 1320 gccgaccaga gccccacacg gaggcatctg caccctcgat gaagcccaat aaacctcttt 1380 tctctg 1386 <210> 136 <211> 1860 <212> DNA <213> HUMAN <400> 136 cgtgaacggt cgttgcagag attgcgggcg gctgagacgc cgcctgcctg gcacctagga 60 gcgcagcgga gccccgacac cgccgccgcc gccatggagt ccgagaccga acccgagccc 120 gtcacgctcc tggtgaagag ccccaaccag cgccaccgcg acttggagct gagtggcgac 180 cgcggctgga gtgtgggcca cctcaaggcc cacctgagcc gcgtctaccc cgagcgtccg 240 cgtccagagg accagaggtt aatttattct gggaagctgt tgttggatca ccaatgtctc 300 agggacttgc ttccaaagca ggaaaaacgg catgttttgc atctggtgtg caatgtgaag 360 agtccttcaa aaatgccaga aatcaacgcc aaggtggctg aatccacaga ggagcctgct 420 ggttctaatc ggggacagta tcctgaggat tcctcaagtg atggtttaag gcaaagggaa 480 gttcttcgga acctttcttc ccctggatgg gaaaacatct caaggcctga agctgcccag 540 caggcattcc aaggcctggg tcctggtttc tccggttaca caccctatgg gtggcttcag 600 ctttcctggt tccagcagat atatgcacga cagtactaca tgcaatattt agcagccact 660 gctgcatcag gggcttttgt tccaccacca agtgcacaag agatacctgt ggtctctgca 720 cctgctccag cccctattca caaccagttt ccagctgaaa accagcctgc caatcagaat 780 gctgctcctc aagtggttgt taatcctgga gccaatcaaa atttgcggat gaatgcacaa 840 ggtggcccta ttgtggaaga agatgatgaa ataaatcgag attggttgga ttggacctat 900 tcagcagcta cattttctgt ttttctcagt atcctctact tctactcctc cctgagcaga 960 ttcctcatgg tcatgggggc caccgttgtt atgtacctgc atcacgttgg gtggtttcca 1020 tttagaccga ggccggttca gaacttccca aatgatggtc ctcctcctga cgttgtaaat 1080 caggacccca acaataactt acaggaaggc actgatcctg aaactgaaga ccccaaccac 1140 ctccctccag acagggatgt actagatggc gagcagacca gcccctcctt tatgagcaca 1200 gcatggcttg tcttcaagac tttctttgcc tctcttcttc cagaaggccc cccagccatc 1260 gcaaactgat ggtgtttgtg ctgtagctgt tggaggcttt gacaggaatg gactggatca 1320 cctgactcca gctagattgc ctctcctgga catggcaatg atgagttttt aaaaaacagt 1380 gtggatgatg atatgctttt gtgagcaagc aaaagcagaa acgtgaagcc gtgatacaaa 1440 ttggtgaaca aaaaatgccc aaggcttctc atgtgtttat tctgaagagc tttaatatat 1500 actctatgta gtttaataag cactgtacgt agaaggcctt aggtgttgca tgtctatgct 1560 tgaggaactt ttccaaatgt gtgtgtctgc atgtgtgttt gtacatagaa gtcatagatg 1620 cagaagtggt tctgctggta agatttgatt cctgttggaa tgtttaaatt acactaagtg 1680 tactacttta tataatcaat gaaattgcta gacatgtttt agcaggactt ttctaggaaa 1740 gacttatgta taattgcttt ttaaaatgca gtgctttact ttaaactaag gggaactttg 1800 cggaggtgaa aacctttgct gggttttctg ttcaataaag ttttactatg aatgaccctg 1860 <210> 137 <211> 1606 <212> DNA <213> HUMAN <400> 137 cgaggtcagc tacgtaaatc cctttgcggc gggataaata aagaaaacag gaaaggagga 60 aagcattgat tacaaatatc ttaacaatga gcaaatgtgc aaggaaaaaa tatattaaga 120 caaatccaag acaaatgacc atggaaacag ttgaatccca gcatgatgga agtataacag 180 cttctttgac agagagcaag tctgctcatg tgcagactca gactggccaa aattcaatcc 240 ctgctttagc tcaggtagca gcaattgcag agacagatga atctgcagaa tcagaaggtg 300 taattgactc tcataaacgt agagaaatcc tttcacgaag accctcttat aggaaaatac 360 tgaatgaact gtcctctgat gtgcctggtg ttccaaagat tgaagaagag agatcagagg 420 aagaaggaac accacctagt attgctacca tggcagtacc aactagcata tatcagacta 480 gcacggggca atacaatgag gaaactgaac ttgccccaag tcacatggct gctgccactg 540 gtgacatgcc aacttaccag atccgagctc ctactgctgc tttgccacag ggagtggtga 600 tggctgcatc gcccggaagt ttgcgcagtc cccagcagct ggcagaagaa gcaacacgca 660 aacgagagct gaggctaatg aaaaacaggg aagctgcccg ggagtgtcgc aggaagaaga 720 aagaatatgt caaatgtctt gaaaatcgtg tggctgtgct tgaaaaccaa aacaagactc 780 tcattgagga actcaaggcc ctcaaagatc tttattgcca taaagtagag taactgtctt 840 tgacttggac cttgtttact ctaactaagg caggagatgc agcagtccta cttattgcca 900 tgtggacttg tgggaaggac acgtgtgacc taagaatcca gtttggatta gtgtttgaaa 960 ttgaattggg aatgttgttc caggatgtgg aatgcagccg tgatcacact taccgagctt 1020 actttgatct gtttgtcaat agcatgcaaa aaagctttgt ttgccctttg cttctgcttt 1080 ttttcaggga agctgccaaa gaatgtcgac gtcgaaagaa agaatatgta aaatgtctgg 1140 agagccgagt tgcagtgctg gaagtccaga acaagaagct gatagaggaa cttgaaacct 1200 tgaaagacat ttgttctccc aaaacagatt actagaaatt atttaactat gaactgaagg 1260 cagcatgtat agttgctttt gaaggaatac aatatatagc tggcaagaat ggtggcttct 1320 tttctttgta tcattcatct tcttctttaa tcattcatct tcttctttaa tcacttaaca 1380 ttcctaaaaa tgcttcactg tacgtagtta agtcgtagct ataacttcaa attttttaaa 1440 agggacaaac tgtaaaaaat gtgtgtattc ttaaaatgca atatttgtaa ggcttgttcc 1500 aatgccacat acttgcagct cccattctat gtgtcatcaa tagtgtccta tgcaataaat 1560 tatttgcagg tctttaaatc attttaggaa ggatgacaaa ataagt 1606 <210> 138 <211> 4894 <212> DNA <213> HUMAN <400> 138 cgaaaacgga gaaaccccgg gtccggcgag aggggctgtg acagtcggag tcccaagctg 60 cggttcggct gctgccgaga actgcaaggt gtggaatatt tctggcttct agtccaatgc 120 caagtgtgtg acctgtggct acatgattcc ctgaaagata agaacaatgt tatgttgggg 180 atattggtct ctgggccaac ctggtatcag caccaacctg cagggaattg tggctgagcc 240 ccaggtgtgt gggttcatat ctgacagaag tgtcaaggaa gtggcctgtg ggggaaacca 300 ctctgtgttc ctgctggaag atggggaagt ttacacatgt ggtttgaaca ccaaggggca 360 actgggccat gagagggaag gaaacaagcc agaacaaatt ggagctctgg cagatcagca 420 tatcattcat gtggcatgtg gcgagtccca cagtctggcc ctcagtgacc gaggccagct 480 gttttcttgg ggtgcaggga gtgatggtca gctaggactc atgactactg aggattctgt 540 ggcagtgccc aggttaatac aaaagctgaa ccagcaaaca atattacaag tttcctgtgg 600 caactggcat tgcttggctc ttgcggctga tggccagttc ttcacctggg gaaagaacag 660 ccatgggcag cttggcttag ggaaggagtt cccctcccaa gccagcccac agagggtgag 720 gtccctggag gggatcccac tggctcaggt ggctgccgga ggggctcaca gctttgccct 780 gtctctctca ggagctgttt ttggctgggg gatgaataat gccgggcagc tagggctcag 840 tgatgaaaaa gatcgagaat ctccatgcca tgtaaaactc ttacgcacgc aaaaagttgt 900 ctatattagt tgtggagaag aacacacagc agttctcaca aagagtggag gtgtgtttac 960 ctttggcgct ggttcctgtg ggcaacttgg acacgactcc atgaatgatg aggttaaccc 1020 tagaagagtt ctagagctga tgggtagtga agtaactcaa attgcttgtg gcagacaaca 1080 taccctagcc ttcgtgcctt cttctggact catctatgca tttggttgtg gagcaagagg 1140 tcaattagga actgggcaca cttgtaatgt taagtgccca tctcctgtca agggttactg 1200 ggctgcccac agtggccagc tttcagcccg agctgatcgc tttaaatatc atatcgttaa 1260 gcagatcttc tctggaggag accagacttt tgtactttgc tccaaatacg agaattattc 1320 tcctgctgtt gacttcagga ctatgaacca agcacattat accagtttaa taaatgatga 1380 aaccatagca gtttggagac aaaaactctc agaacacaac aatgcaaata caatcaatgg 1440 tgttgttcag atattatctt ctgcagcctg ttggaatgga agttttcttg aaaaaaaaat 1500 tgatgaacat tttaaaacga gtcccaaaat ccctgggatt gacctgaact caactagggt 1560 gttatttgag aagttaatga actctcagca ctccatgatt ctagaacaga ttttgaacag 1620 ttttgaaagt tgtctgattc cccagttgtc aagctcacca ccagatgttg aagccatgag 1680 aatctattta atactacctg agtttcccct actccaggat tccaagtatt atataacatt 1740 gactattccc ttggctatgg ccattcttcg gctggataca aaccccagca aagtactaga 1800 taactggtgg tctcaggtat gcccgaaata tttcatgaag ctggtaaacc tctataaagg 1860 tgcagtcctt tatctactga ggggaagaaa gacattctta attcccgtac tgtttaacaa 1920 ttatatcaca gcagctctca aactcttgga gaagttatat aaggtaaatc ttaaagtgaa 1980 gcatgtggaa tatgatacat tttacattcc tgagatttcc aatctcgtgg acattcagga 2040 agactacctc atgtggttct tgcatcaagc agggatgaag gctagaccat caataataca 2100 ggatactgta acactttgtt cctacccttt catctttgat gcccaagcca agaccaaaat 2160 gttacagaca gatgctgaac tacagatgca ggtggcagtc aatggagcca acctgcagaa 2220 tgtcttcatg cttctcaccc tggagcctct gctggccaga agccccttcc tggtccttca 2280 cgttcgcagg aacaaccttg ttggagatgc cctaagagag ctgagcattc attctgatat 2340 tgatttgaaa aagcctctca aagtaatctt tgatggtgaa gaagcagtgg atgccggtgg 2400 tgttacaaag gaattttttc ttttgctgtt aaaagaactt ttgaatccca tctatggaat 2460 gtttacctac tatcaagatt caaatctctt gtggttttca gacacgtgtt ttgtagagca 2520 caactggttt cacttgattg gtataacctg tggactagct atctacaact ccactgtggt 2580 cgatctccac ttcccattgg ctctctacaa gaagttactc aatgtaaagc ctggcttgga 2640 agacttaaag gagttgtcac ccactgaagg aaggagtctc caagagcttt tagattaccc 2700 cggggaggat gtggaggaga ctttctgcct caacttcacg atctgccgag aaagctatgg 2760 agtgattgaa cagaagaagc tgatacctgg gggagataat gtaactgtgt gcaaggataa 2820 caggcaggaa tttgtggatg cttatgtgaa ttatgtcttc caaatctcag ttcatgaatg 2880 gtacacagcc ttctctagtg gcttcctaaa ggtgtgtggt ggcaaagtac ttgagctctt 2940 ccagccttca gaactgaggg ctatgatggt ggggaacagc aactacaact gggaagaact 3000 ggaagagact gccatctaca agggagatta ctcggccaca catcccactg taaaactatt 3060 ttgggaaaca tttcatgagt ttccattgga aaagaagaag aagtttctct tgttcctgac 3120 aggcagcgat cggattccca tctacggcat ggccagtctg cagattgtca tccagtccac 3180 agccagcggg gaggagtact tgccggtggc ccacacttgc tacaaccttc ttgacctccc 3240 caagtacagc agcaaagaga ttctgagtgc ccggctgacc caggcccttg acaactatga 3300 agggtttagt ttggcctgag gcttctcagc ttgtccagta tttcccttcg ttcctcagtg 3360 tccacattga ggcctataca gaaaatcatg gggagtgatt tctatttttt tattgtctaa 3420 gtgggttggg acttttaaat actgagcctg gttgatgtgt ttctgggatt gtatagcagt 3480 aaacaacctt tttgaaaaat tagaggttgg ggatggggtg aaaaattggc ccttgtatgg 3540 gaggtgtttt tgtttttgtt ttaaaccaaa ctacccagta ttccttgcac ttgtgaatgt 3600 gttgcactct gctggatgaa atggcagtgg atttttaaac tttaatttcc caaatgtctc 3660 tctcagccct gatgttttct cacagtgctt ccttgtcctt ctcttaactt ctcattcctc 3720 tataagaatg atttagactg acctgtcctt ttttatctgc gcatgcgaga acatcacctt 3780 cctctgtaca cttggaaatg cctctggctt gttgcagccc tcctttaacc caaaggagga 3840 aaggactgct tcagaaactc ccaattccaa aaagctgagt ctgggtccat tattttggca 3900 gaactcctaa gaatttatgg gagcctatat aaacatatct tgcttttaaa aagttcttga 3960 gggaatagca actttcccat ggctgtgcct atttcctaga ccttttaaaa gatgtgcaga 4020 gcagcttagc attcgttgca gctgagccta attttttctt gctcatcctt gtccctttga 4080 caataaggtt aattgataga cccaccacct cttgcactct cgcttttgga gcaagttgca 4140 ttaactattt tgagtctcta tattgtccaa gaaaagtaga aataataaat ttactttccc 4200 tttttctatc accttatgtc ctctaccatt ttctccttcc tcccttccct tattttctcc 4260 ttttcgtacc ctgtgtcctc cctgattttc ctttcgtttc ttctttattt tatcccattc 4320 tctgttactt gactcagtgc tcccttcctc tcctctcctt ctagtggatg catgcagcct 4380 ttttttcaat ttttatttaa attgcaaaat ttttactcag attttttttc ctcttcccta 4440 attgctaaga tttaaggacg ttctttatta tgaaacttta tcacattcga aatgtttgtt 4500 tacagtggga ttttaggggg gattgtgttt aaatcaaata tatgtatttt aaaaataatg 4560 acatgctcaa ccttcctcat catggagtaa gaaaattcta catgattaaa gaatccatgt 4620 aagtctaatt ttaaattcct agtaactaga gaaaagactt atttatataa aatgaagtat 4680 ttatgaactg tgataaagca tcaaatcttg atgaaggatt gtagattttt gctttttctt 4740 tttgttttta aaacttattc caattgctaa attggtagtt tttcagtctt tataaataca 4800 ggattaaaaa tatatataca gttatatgaa atgtttattt tctatgtgtg tgcatatagt 4860 tcaatattat gcaataaatt tggtgtttta actt 4894 <210> 139 <211> 5323 <212> DNA <213> HUMAN <400> 139 cggggctgga ggcggtggct gcggttgcgg gaccggcact atgctgggcc ttcctaccac 60 ttgtgtgtgg cttggtagtg gcctagggtc tctcctccct gctgaagtcc ctctcctgca 120 ggtggccgtc tgcccggccc agcaccatgc acacgcttgt gttcttgagc acacggcagg 180 tgctgcagtg ccagccagct gcctgccagg ccctgcccct gctgccacgc gaactcttcc 240 ccctgctgtt caaggtggcc ttcatggaca agaagacagt ggtactgcgc gagttggtac 300 acacgtggcc cttcccgctg ctcagtttcc agcagctgct acaggagtgt gcccactgca 360 gccgtgccct cctgcaggag cggcctagca ctgagagcat gcaggctgtt atcctggggc 420 tgactgcccg gctccacacc tcagagcctg gggccagcac acagcccctc tgcaggaagc 480 atgcgctgcg ggtgctggac atgacgggcc tcttggatga tggtgtggaa caggatcctg 540 gcaccatgag catgtgggac tgtactgctg ccgtagctcg cacatgcatt gcccagcagc 600 agggtggggc cgcagagcct gggccagccc ccatccccgt ggaggtgcgc gtggacctgc 660 gggtgaaccg ggcctcctat gcgttcctgc gggaggcact ccgaagcagc gtgggcagcc 720 cgctgcggct ctgctgccgg gacctgcgag ctgaggacct gcccatgcgc aacactgtgg 780 ccctgctgca gcttctggat gcaggctgcc tgcgccgcgt ggacctgcgc ttcaacaatc 840 tgggcctgcg cggcctgtct gtgatcatcc cacacgtggc ccgcttccag cacctggcca 900 gcctgcggct ccactatgtg catggggatt caaggcagcc ctccgtggat ggcgaggaca 960 acttccgcta cttccttgcc cagatgggcc gcttcacctg tctgcgtgag ctcagcatgg 1020 gctcctctct cctttcaggg aggctggacc agctgctcag caccctgcag agccccctgg 1080 agagcctgga gttggccttc tgtgctctgc tgcctgagga cctacgcttc ctggcacgga 1140 gcccacatgc tgcccacctc aagaagttgg acctgagtgg taacgacctg tctggcagcc 1200 agctggcacc cttccagggt ctgttgcagg catcagcagc cacactgttg catctggagc 1260 tgactgagtg tcagctcgca gacacccagc tgttggccac actacccatc ctgactcagt 1320 gcgccagtct ccggtacctt ggcctctatg gcaacccact gtccatggcg ggcctcaagg 1380 agctgctgcg ggactcagtg gcacaggctg agctgcgtac tgtggtgcac cccttccctg 1440 tggactgcta tgagggcttg ccctggccgc cgcctgcctc tgtcctgctg gaggcctcca 1500 tcaatgagga gaagtttgcc cgcgtagaag ctgagttgca ccagctgctt ctagcctcag 1560 gccgtgccca tgtgctctgg accacggaca tctacgggcg actggctgcg gactacttca 1620 gcctatgatg aagtagctct gggtgagaca caggccgccc tgcagtctct ttaggtaggc 1680 agggcctttg ctgggacccc tggtggaggc cttcacaaaa gcactggtta ctggtttcct 1740 gctgggtcta ccttgcttct gggcacacct caagcctccc ctgctttctg cagtgcccca 1800 cgcggttttc cctgcacttg ctccataatt ggctgatcat ctgtgggccc cggggctgga 1860 tgtcaggcct ccattgccct gctcagtttg gctgcatttg gctgccgtct ggggtcctgg 1920 tcctttgtgc aaatgctttg ggattccagt tgtgagctga gagagatgat ggcctctctg 1980 ggcctttcct ctccctttac tgagagctca gtgcttctgg ggttgaagtt ggacagaggc 2040 ctgcttcagg gaagctggga gtccccaggc actcacgcct cttacgtgtt ccctaccctg 2100 ccacccagcc accccactgg gctgggctcg ggctggaggg ggtcatcaag gtacacatgt 2160 gcctggaagt tgaatttgtg gctgtttttt tttctgtcca cgttggtcac ccttatcctt 2220 atctctgctg tcacccccaa catggccacc gggcaacaac tgccatccag cctgtcgccc 2280 cgcccttcgc ggggcagccc cgtcggcact gccggccagt ccttgctctt cccacctttc 2340 ggaggcccaa gatcctactg tggccggcca gggccagcga gggacccccc ccatgcagag 2400 ctggaggttg gggtgatgtc ttttcggaag agcttcaagg gaggtgttgg ggcctccccg 2460 gccaccttcc attgctaccc caggattccc gagtgcaacg ttcccggctc gcgccccaca 2520 cacggctcag cgcacactgc gcggcttcca cctttactga cggagcatgc gcgaggccgc 2580 accggccaat ctccggcgcc cacgtcatcc gcgcgcccgc ggccctagca gtggatctcg 2640 taggcgaccg gcgggggcac gcggagtccc ggccccgccc cctgttccgg gccgcagtca 2700 gcgggcgcct ccgccggacc ctcggcgaag agcggcttgg agcggttgat gacgaacatc 2760 tcgtggccgc gctcgtcgcg gagctcctct agctgtgcga acgtacaggg gccgtccaag 2820 tagtcgttga cgaacagcgc tccctccccc ggaggccccc gcgccttttt tcgcctgcgg 2880 cgccggcgac agatcatggc gaccaggagc agcgccgtga gcgccagcag cgcgatggcc 2940 gccgcaatgg ccgtctgtgt ggccacgccc agggcgcgga aggccatgct gcccgcctcg 3000 ggccggggct cgctgccggc ggggcgggcg gccggaggcg gcggttgcgc gggctgctgc 3060 ggctgctgcc gggacgcgtt gaccaggagc cggaagggca cgcgggcagc gccgccggcg 3120 ttggaggcct cgcactcgta cttaccggcg tgcgccagcg tgatgttgct gaggaagagc 3180 atgccgctgc ccgtgtcgga tgccgagtgt ccgcccaggc ccagcaaccc gccttctagc 3240 tgggcctggg ctcgcggccg gccctcgcga ggctggggca cctttctcca ggtcaccaat 3300 ggctgcgggt agccggaggc ttggcaggca acccgcaggt cctcacccag gttggctgtg 3360 agctccagcg gctgcacgtg gacagagggc ggaatgcaga tgaggctgct gtgggatacg 3420 tccaggagac tctggagcgc caggcgcggg ggctctgcac acatgatctt cctgtccctg 3480 gaggtgagca gccgctggcc gccctccttg atccaggccc ccagccagtg cagggcgcag 3540 tcacagcgcc atgggttctc tgtgggagag cagcgttagg caggtggctt gagggtgctg 3600 ctaaaacagc ctgtgcagtt ggggttttgc aggccaggac agaggcctct ttcccacctc 3660 ccacagcgtt ttcacacgga gtccaaggcc ctgccacccc ttccttgacc ccaagctcct 3720 tggggcggca ggcccttcac cctcgccccc ctccccttta gctctgtgat gcctgcctgt 3780 tacagatcac ttctccgtcg gtctctgaga aagcacctgc tccttaagtc ttcctgcaac 3840 aagtgccact gtttttagga acctgggcgt ccacatagac atctcaccag cactgaaacc 3900 tcacaagtcc tctcagcttt gcctttggat gccctctctt gggaatgtcc ccagtcctgg 3960 tcagctgtct ctctcctttg caattttgtc tgcctcccct cagcctaaaa gtgtgcagaa 4020 ccctcaattc tgttaagtca ccctgtggag ttcctgtctt ctgttttccc caggcagggt 4080 gcctgagctg tatcccccag cacacccact cccgcagccc tccagtgtgg ctgcaggcgg 4140 tggtgcagcc ttccagactg ctgcccagtt gcctgatgtc agagcccctc cacacatgag 4200 cctgctccct actgccaaca ccgtggccca gacagagacg ctttccgagg aagaggtacc 4260 tgtgaggcgc aggacttgca gactggccag gggctgcagg gcctctcggc tgatggtgcc 4320 cagctggttc ctgctgaggt ccagcagtgc tagggaggac agccccgcta gagcctggtc 4380 ctccagcagc tcaatgctgt tttcttgcag gtgaagctcc tgcagtcgct gaagtaagga 4440 cagcagatcg tgaggaaaaa gggcgccgag gttgggggca tgtctctctt cttaccaagc 4500 tagactgggt tgccttttct aactattcca gccctacagg gcgaggggcc ataatggagt 4560 atcccgcccc tttagacccc aggcgctcac cggcaggtgc aagaaggtga aatccagcag 4620 ccgcgccagc tggttgcccg ccaggtagag cacgcgcagc tgggccaggc ctacgaaggc 4680 gccgctgcgc aagccgcgca gccggttgct agtgagcgcc agctccagca ggcgcggctg 4740 cgcgcggaag gcgccggcct ccagggcgcg caggctgttg ttgtgcaggt agagccggcg 4800 cagagcggcg agtggcgcca gggctcccgg ctctaggcgg gcgatgttgt tgtcctgcag 4860 gaacagtgtc tgcaggccgg ggaaagagga ggcgcttacc ccgctgcggg ggtcttcctc 4920 tccctggggg caccccgtcc tcccgcagct ccacacggtg cccacctgcg tccctggcgg 4980 gattcccagc gggacgacgc gcaaccgcag ggcgccacac tccaccgtgg cgctgtagca 5040 gcggcaggct gctgggcagc cggcggcgcg gagcggcagt agtagcagca gcagcggcag 5100 cagttcgggg gccctcaggg ccatctcccg aggcccggtt cctcaccggc ccttccgcgg 5160 ttcagccgca gacgcgtgcc ctcctgaaac acaggttggc aggccagtct cggcagtcga 5220 gagccagcca atagatggaa tggaggcctg cacctgcgtc taacttttga cactataaat 5280 aggttcaaga aactaataaa acgttctggt tttctccttt gac 5323 <210> 140 <211> 1194 <212> DNA <213> HUMAN <400> 140 ttaattcggc ggccgcggat ccgagccgga cgggcactgg gcgactctgt gcttcgctga 60 ggaaaaataa ctaaacatgg gcaaaggaga tcctaagaag ccgagacgga aaatgtcatc 120 atatgcattt tttgtgcaaa cttgtcggga ggagcataag aagaagcacc cagatgcttc 180 agtcaacttc tcagagtttt ctaagaagtg ctcagagagg tggaagacca tgtctgctaa 240 agagaaagga aaatttgaag atatggcaaa agcggacaag gcccgttatg aaagagaaat 300 gaaaacctat atccctccca aaggggagac aaaaaagaag ttcaaggatc ccaatgcacc 360 caagaggcct ccttcggcct tcttcctctt ctgctctgag tatcgcccaa aaatcaaagg 420 agaacatcct ggcctgtcca ttggtgatgt tgcgaagaaa ctgggagaga tgtggaataa 480 cactgctgca gatgacaagc agccttatga aaagaaggct gaaaagctga aggaaaaata 540 cgaaaaggat attgctgcat atcgagctaa aggaaagcct gatgcagcaa aaaagggagt 600 tgtcaaggct gaaaaaagca agaaaaagaa ggaagaggag gaaggtgagg aagatgaaga 660 ggatgaggag gaggaggaag atgaagaaga tgaagatgaa gaagaagatg atgatgatga 720 ataagttggt tctagcgcag tttttttttt cttgtctata aagcatttaa cccccctgta 780 cacaactcac tccttttaaa gaaaaaaatt gaaatgtaag gctgtgtaag atttgttttt 840 aaactgtaca gtgtcttttt ttgtatagtt aacacactac cgaatgtgtc tttagatagc 900 cctgtcctgg tggtatcttc aatagccact aaccctgcct ggtacagtat gggggttgta 960 aattggcatg gaaatttaaa gcaggttctt gtttgggcac agcacaaatt agttatatat 1020 ggggatggta gttttttcat cttcagttgt ctctgatgca gctatacgaa ataattgttg 1080 ttctgttaac tgaataccac tctgtaattg caaaaaaaaa aaaaaagttg cagctgtttt 1140 gttgacattc tgaatgcttc taagtaaata caattttttt tattaaaaaa aaaa 1194 <210> 141 <211> 2015 <212> DNA <213> HUMAN <400> 141 gttttctact ttgcccgccc acagatgtag ttttctctgc gcgtgtgcgt tttccctcct 60 cccccgccct cagggtccac ggccaccatg gcgtattagg ggcagcagtg cctgcggcag 120 cattggcctt tgcagcggcg gcagcagcac caggctctgc agcggcaacc cccagcggct 180 taagccatgg cgtgagtacc ggggcgggtc gtccagctgt gctcctgggg ccggcgcggg 240 ttttggattg gtggggtgcg gcctggggcc agggcggtgc cgccaagggg gaagcgattt 300 aacgagcgcc cgggacgcgt ggtctttgct tgggtgtccc cgagacgctc gcgtgcctgg 360 gatcgggaaa gcgtagtcgg gtgcccggac tgcttcccca ggagccctac agccctcgga 420 ccccgagccc cgcaaggtcc caggggtctt ggctgttgcc ccacgaaacg tgcaggaacc 480 aagatggcgg cggcagggcg gcggcgcggg cgtgagtcaa gggcgggcgg tgggcggggc 540 gcggccgctg gccgtatttg gacgtgggga cggagcgctt tcctcttggc ggccggtgga 600 agaatcccct ggtctccgtg agcgtccatt ttgtggaacc tgagttgcaa gcagggaggg 660 gcaaatacaa ctgccctgtt cccgattctc tagatggccg atctagagaa gtcccgcctc 720 ataagtggaa ggatgaaatt ctcagaacag ctaacctcta atgggagttg gcttctgatt 780 ctcattcagg cttctcacgg cattcagcag cagcgttgct gtaaccgaca aagacacctt 840 cgaattaagc acattcctcg attccagcaa agcaccgcaa catgaccgaa atgagcttcc 900 tgagcagcga ggtgttggtg ggggacttga tgtccccctt cgacccgtcg ggtttggggg 960 ctgaagaaag cctaggtctc ttagatgatt acctggaggt ggccaagcac ttcaaacctc 1020 atgggttctc cagcgacaag gctaaggcgg gctcctccga atggctggct gtggatgggt 1080 tggtcagtcc ctccaacaac agcaaggagg atgccttctc cgggacagat tggatgttgg 1140 agaaaatgga tttgaaggag ttcgacttgg atgccctgtt gggtatagat gacctggaaa 1200 ccatgccaga tgaccttctg accacgttgg atgacacttg tgatctcttt gcccccctag 1260 tccaggagac taataagcag cccccccaga cggtgaaccc aattggccat ctcccagaaa 1320 gtttaacaaa acccgaccag gttgccccct tcaccttctt acaacctctt cccctttccc 1380 caggggtcct gtcctccact ccagatcatt cctttagttt agagctgggc agtgaagtgg 1440 atatcactga aggagatagg aagccagact acactgctta cgttgccatg atccctcagt 1500 gcataaagga ggaagacacc ccttcagata atgatagtgg catctgtatg agcccagagt 1560 cctatctggg gtctcctcag cacagcccct ctaccagggg ctctccaaat aggagcctcc 1620 catctccagg tgttctctgt gggtctgccc gtcccaaacc ttacgatcct cctggagaga 1680 agatggtagc agcaaaagta aagggtgaga aactggataa gaagctgaaa aaaatggagc 1740 aaaacaagac agcagccact aggtaccgcc agaagaagag ggcggagcag gaggctctta 1800 ctggtgagtg caaagagctg gaaaagaaga acgaggctct aaaagagagg gcggattccc 1860 tggccaagga gatccagtac ctgaaagatt tgatagaaga ggtccgcaag gcaaggggga 1920 agaaaagggt cccctagttg aggatagtca ggagcgtcaa tgtgcttgta catagagtgc 1980 tgtagctgtg tgttccaata aattattttg taggg 2015 <210> 142 <211> 457 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(457) <223> N=any base <400> 142 tttttttttt tttttttttt acgtttaacc taattttatt catgcttgcc ttgggatggg 60 gaatagatca ttcagtaaaa acatacagta aaaacaaaat gtcttatcat gtacaacttt 120 caaactacaa taatgatgta ccttaattac ttccatgcac acaagtctaa catttgtttt 180 tttaaaaaat aaacacaatt aagacttcta ggagcatttt ataataaagt aattcctaat 240 taattttnct ttgtagatag atcaagcacc tccaaaatac aaattcctat acacagtgag 300 gcacgttact taaaatgaac acttaagtaa attaaggtac gtgggacagg ccttaggggt 360 aagctggaca ttataggtgg cggctagggt agggcaacaa accntaggtg gcccantggg 420 gaaaagtttt tttggcaaat taatttttaa aaactag 457 <210> 143 <211> 393 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(393) <223> N=any base <400> 143 tttttttttt ntttttttta aggattttaa aaatatatct attttgaaaa tattctgaaa 60 gtaattaaga tcacctattg ggaaggaaag aaatcaacac aatgaaattt aggaagagaa 120 atgcaaaagc agctgcagaa tcctgcccct tccaccccaa ggggcacagc cggnaggatg 180 aagcttattt taggatcaca agtgcacgct ctggtaggac ggaggatgac tttgtcagtc 240 ttctgggctg aagggccttg tccaaagtca ggatcagaaa tagggtcagc tcatcatgct 300 tgggctttgt tgggtcttgg tagttaggat aagggttcaa gggctttntt tttccatgag 360 gggagagatt tgggacactt cgcagggttt acg 393 <210> 144 <211> 320 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(320) <223> N=any base <400> 144 gtgttgagtt ggaagaattg gcaaaatatc tggaccatta agaaaacgga ttttgtaact 60 agctttaaac taggccaagc aactagtttt cctgcaaatc aaatttttaa agcaacttgg 120 gttagacttt gtttttgacc taacatccct tccttaaatg ccttctgtag tttcagatca 180 gtagggagac catataataa ttttatggta cctgtttcaa aacatatttt ttctgttttt 240 ataagtaagt tgatattaat taaactcttg gcaatatttc tnctttctta aaggaaaata 300 taccttaact ttttttcttt 320 <210> 145 <211> 461 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(461) <223> N=any base <400> 145 atntatnttg ggcagggctt gatctggaaa gaagtttgga aaccctgggg agaaattagt 60 taaaaagaag tggaatcttg atgagctgcc taaatttgag aagaattttt atcaagagca 120 ccctgatttg gctaggcgca cagcacaaga ggtggaaaca tacagaagaa gcaaggaaat 180 tacagttaga ggtcacaact gcccgaagcc agttctaaat ttttatgaag ccaatttccc 240 tgcaaatgtc atgggatgtt attgcaagac agaattttca ctgaacccca ctgctatttc 300 aaggctcagg gggtgggcca gtttgctctt agtggggttt gggtatgggg ttgggagttg 360 gccacagact tggatcnttg ggggaaacat tgtccttatt tttgctttcc ccgcccattt 420 ttccccccat ncattcnttc aggcctttcc ncgggggaga g 461 <210> 146 <211> 478 <212> DNA <213> HUMAN <400> 146 gcctactatg ccagatgcct ttatggctga aaccgcaaca cccatcacca cttcaataga 60 tcaaagtcca gcaggcaagg acggccttca actgaaaaga ctcagtgttc cctttcctac 120 tctcaggatc aagaaagtgt tggctaatga agggaaagga tattttcttc caagcaaagg 180 tgaagagacc aagactctga aatctcagaa ttccttttct aactctccct tgctcgctgt 240 aaaatcttgg cacagaaaca caatattttg tggctttctt tcttttgccc ttcacagtgt 300 ttcgacagct gattacacag ttcctgtcat aaggaatgaa taattaatta tccagagttt 360 agaggaaaaa aatgactaaa aatattatta acttaaaaaa tggacaggtg ttggatgccc 420 acaggcaaat gcatgggggg gttgtttaat gggtgcaaat ccctacttga atgctctt 478 <210> 147 <211> 468 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(468) <223> N=any base <400> 147 ntnnnttnna agtctaagtg tttaattatt attcacatat ttcacagaaa aaaaggaatg 60 tagcaaaggg gtcaagattg tagcaaaaaa caaaaaatcc tggattttac gggtcactct 120 atttgtactt gggagcaggg ctgtcccgac atcaggcgca nagctgcact tctccgatgc 180 ccctttgcag atgcagccct gggcacactt ggcacagccc acaggnagnc aggagcagca 240 gctcttcttg caggaggtgc atttgcctct ttgcacttgc aggagctggc gcaggtgcag 300 gagacaccag cggcacagga gcagttgggg gtccatttgc aacccgaggg cgagactagg 360 agttcccaag gcgagaaggg gaaggagggc agtggggttg cacgtnggaa gggnttaggg 420 gtnccagcac gtggggttng taccccnggg cctngggttc agacaggg 468 <210> 148 <211> 425 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(425) <223> N=any base <400> 148 ctctcaatgg gcgcacgggc tacgttctgc agcctgagag catgaggaca gagaaatatg 60 acccgatgcc acccgagtcc cagaggaaga tcctgatgac gctgacagtc aaggttctcg 120 gtgctcgcca tctccccaaa cttggacgaa gtattgcctg tncctttgta gaagtggagn 180 tctgtggagc cgagtatgac aacaacaagt tcaagacgac ggttgtgaat gataatggcc 240 tcagncctat ctgggctcca acacaggaga aggtgacatt tganatttat gacccaaacc 300 tgggnatttt ttgcgcttng tggtttattg aaggaaggta ttgtttcagc gnttccccaa 360 ttttttttgg ntcatggcca ctttacccct ttaaaggcag tcaaaatcag ggnttcaggg 420 tncct 425 <210> 149 <211> 440 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(440) <223> N=any base <400> 149 actataactt agtgtctgta tttaatattg acaaccaaaa atatatatan ttttnttgca 60 tctatacaca acagggcagg agtctccatg tnttcttgag cagtgagttt gcaggctccc 120 acaggccctc ttctcatggt aatagtgtgg ccctagtgca aaggagacta gaacccggca 180 gcccagactg gcccttcccc tctcctccct gcactccagt gcttcccaac tggtctcagg 240 taaagaaagn ttantttgag tggttgggta ggaagagatg ggaaggggca aatcctaatg 300 ggagcctgac ccctagagtg gggagttcca gggccagcag aacgggtggg ccatagccct 360 ncctggggnt agaagctttg tagttcatag ttcgattagt ntgtccntag ggcatnaggt 420 nccagcccta cagattagct 440 <210> 150 <211> 253 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(253) <223> N=any base <400> 150 gcttatttta gctgcaaagt ggcatcatat tatnccattt aatgaaattc acctcaagcc 60 ctttttgaca tattaaatat atgggatata tttaaggcaa gagaagtaag gcaatccaaa 120 tgagtgccct ttcccaatct cagcactgtc ttggtggaat tggtgacact attcagataa 180 ccaactggag accgacagga tttgccatgc atttgcatct tgctagagtt tggtttttat 240 gaaagggcct att 253 <210> 151 <211> 382 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(382) <223> N=any base <400> 151 ccccaggctg gagtgcagtg gcatactcat ggctcactga cgcctccaat tcctaaactc 60 caatgacctt ctcacctcag cctgcaagta gctaggatta cagatgtgtg ccgccatgct 120 aattttnaaa aattttttgt atagatgggt nctcactatg agcccaggct catcttgaag 180 tnctgggctc aagcaatcct ctnaccttgg cttcccaaag tactgggatt acaggcggga 240 cacncatgcc agccgtcact ctcatttttg agcacaggaa ttgtgcccaa aggctaggat 300 aaggaattaa agatgcatgc caagaaatac ccacaaacat taattataaa aggggagact 360 atacnaatgt tttgtggaaa ag 382 <210> 152 <211> 408 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(408) <223> N=any base <400> 152 aaatagaaat aacagctaac aggaggtttg gagtttcctc atttatgtct tttcctatga 60 accttgattt aaagctggac ttgcaggacc attgacagaa tgttctggcc cctcagtgcc 120 actcgtgggt tcagaacctt cagcctgttc ctttgcttca gggagctttt ctggggcacc 180 aagtggatta acacagttag gcatcctgct ttactttgtc cacttcatta tcaaattcaa 240 ttttatcttc ttgatgggtt gtttttcttt acttgtccat tctgaggcag ggtagggtgc 300 tgggcaatga cgtcatatag ggaattgata ttgctcggaa tgtgggaaac catggcccgg 360 gnctaggctt tgcgtaggag gctttttacc acttgaaaaa tatccant 408 <210> 153 <211> 368 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(368) <223> N=any base <400> 153 ctcgnccacc acccaatcct cgcctctctt ctgctccacc ttctctctct gccctcacct 60 ctcccccgaa aaccccctat ttagccaaag gaaggaggtc aggggaacgc tctcccctcc 120 ccttccaaaa aacaaaaaca gaaaaaccct tttccaggcc ggggaaagca ggagggagag 180 gggccgccgg gctggccatg gagctgctgt gccacgaggt ggacccggtc cgcaggcctt 240 gcgggtaccg caacctgctc cgagacgacc gcgtcctgca gaacctgctt caccatcgag 300 gagcgnttac cttnccgcag tgnttcctaa ttncaagttg cgtgnagaag gacatccaaa 360 cctnacat 368 <210> 154 <211> 442 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(442) <223> N=any base <400> 154 cgtttaacaa aattgtttaa taaaatttat aaaaatgcat ctttgagaat acttttctca 60 gcttgaattg ttttcctttt ccacccccaa agaaaataca caattatcag cacccacaca 120 tgtatacact caaaactaca gtgacattct ctacacagaa ctatattcga tatagcttga 180 actgccgaaa aatcaagaca attccaaaaa gtgattgcag ggttgatttt tttctccaaa 240 acactttgag aaacacgtaa agctatttca acaaaagtct tttctttgat tgtcaaaagt 300 tgaaattcac atttaaataa aaagagatcc aaatcaagat cctcactnac cccctacccc 360 tcaactgaac ccccttttag ggccacattt tcttcttgct cctaagaaaa aaatttggaa 420 ttttgaatat tctcggtttt ct 442 <210> 155 <211> 1947 <212> DNA <213> HUMAN <400> 155 tgcagctgcc tggctgcctg gccctggctg ccctgtgtag ccttgtgcac agccagcatg 60 tgttcctggc tcctcagcaa gcacggtcgc tgctccagcg ggtccggcga gccaacacct 120 tcttggagga ggtgcgcaag ggcaacctag agcgagagtg cgtggaggag acgtgcagct 180 acgaggaggc cttcgaggct ctggagtcct ccacggctac ggatgtgttc tgggccaagt 240 acacagcttg tgagacagcg aggacgcctc gagataagct tgctgcatgt ctggaaggta 300 actgtgctga gggtctgggt acgaactacc gagggcatgt gaacatcacc cggtcaggca 360 ttgagtgcca gctatggagg agtcgctacc cacataagcc tgaaatcaac tccactaccc 420 atcctggggc cgacctacag gagaatttct gccgcaaccc cgacagcagc aacacgggac 480 cctggtgcta cactacagac cccaccgtga ggaggcagga atgcagcatc cctgtctgtg 540 gccaggatca agtcactgta gcgatgactc cacgctccga aggctccagt gtgaatctgt 600 cacctccatt ggagcagtgt gtccctgatc gggggcagca gtaccagggg cgcctggcgg 660 tgaccacaca tgggctcccc tgcctggcct gggccagcgc acaggccaag gccctgagca 720 agcaccagga cttcaactca gctgtgcagc tggtggagaa cttctgccgc aacccagacg 780 gggatgagga gggcgtgtgg tgctatgtgg ccgggaagcc tggcgacttt gggtactgcg 840 acctcaacta ttgtgaggag gccgtggagg aggagacagg agatgggctg gatgaggact 900 cagacagggc catcgaaggg cgtaccgcca caagtgagta ccagactttc ttcaatccga 960 ggacctttgg ctcgggagag gcagactgtg ggctgcgacc tctgttcgag aagaagtcgc 1020 tggaggacaa aaccgaaaga gagctcctgg aatcctacat cgacgggcgc attgtggagg 1080 gctcggatgc agagatcggc atgtcacctt ggcaggtgat gcttttccgg aagagtcccc 1140 aggagctgct gtgtggggcc agcctcatca gtgaccgctg ggtcctcacc gccgcccact 1200 gcctcctgta cccgccctgg gacaagaact tcaccgagaa tgaccttctg gtgcgcattg 1260 gcaagcactc ccgcaccagg tacgagcgaa acattgaaaa gatatccatg ttggaaaaga 1320 tctacatcca ccccaggtac aactggcggg agaacctgga ccgggacatt gccctgatga 1380 agctgaagaa gcctgttgcc ttcagtgact acattcaccc tgtgtgtctg cccgacaggg 1440 agacggcagc cagcttgctc caggctggat acaaggggcg ggtgacaggc tggggcaacc 1500 tgaaggagac gtggacagcc aacgttggta aggggcagcc cagtgtcctg caggtggtga 1560 acctgcccat tgtggagcgg ccggtctgca aggactccac ccggatccgc atcactgaca 1620 acatgttctg tgctggttac aagcctgatg aagggaaacg aggggatgcc tgtgaaggtg 1680 acagtggggg accctttgtc atgaagagcc cctttaacaa ccgctggtat caaatgggca 1740 tcgtctcatg gggtgaaggc tgtgaccggg atgggaaata tggcttctac acacatgtgt 1800 tccgcctgaa gaagtggata cagaaggtca ttgatcagtt tggagagtag ggggccactc 1860 atattctggg ctcctggaac caatcccgtg aaagaattat ttttgtgttt ctaaaactat 1920 ggttcccaat aaaagtgact ctcagcg 1947 <210> 156 <211> 4792 <212> DNA <213> HUMAN <400> 156 ggaccaccca gtaccgatcc cttcacgacc gtcaccatgg aagtgtcacc attgcagcct 60 gtaaatgaaa atatgcaagt caacaaaata aagaaaaatg aagatgctaa gaaaagactg 120 tctgttgaaa gaatctatca aaagaaaaca caattggaac atattttgct ccgcccagac 180 acctacattg gttctgtgga attagtgacc cagcaaatgt gggtttacga tgaagatgtt 240 ggcattaact atagggaagt cacttttgtt cctggtttgt acaaaatctt tgatgagatt 300 ctagttaatg ctgcggacaa caaacaaagg gacccaaaaa tgtcttgtat tagagtcaca 360 attgatccgg aaaacaattt aattagtata tggaataatg gaaaaggtat tcctgttgtt 420 gaacacaaag ttgaaaagat gtatgtccca gctctcatat ttggacagct cctaacttct 480 agtaactatg atgatgatga aaagaaagtg acaggtggtc gaaatggcta tggagccaaa 540 ttgtgtaaca tattcagtac caaatttact gtggaaacag ccagtagaga atacaagaaa 600 atgttcaaac agacatggat ggataatatg ggaagagctg gtgagatgga actcaagccc 660 ttcaatggag aagattatac atgtatcacc tttcagcctg atttgtctaa gtttaaaatg 720 caaagcctgg acaaagatat tgttgcacta atggtcagaa gagcatatga tattgctgga 780 tccaccaaag atgtcaaagt ctttcttaat ggaaataaac tgccagtaaa aggatttcgt 840 agttatgtgg acatgtattt gaaggacaag ttggatgaaa ctggtaactc cttgaaagta 900 atacatgaac aagtaaacca caggtgggaa gtgtgtttaa ctatgagtga aaaaggcttt 960 cagcaaatta gctttgtcaa cagcattgct acatccaagg gtggcagaca tgttgattat 1020 gtagctgatc agattgtgac taaacttgtt gatgttgtga agaagaagaa caagggtggt 1080 gttgcagtaa aagcacatca ggtgaaaaat cacatgtgga tttttgtaaa tgccttaatt 1140 gaaaacccaa cctttgactc tcagacaaaa gaaaacatga ctttacaacc caagagcttt 1200 ggatcaacat gccaattgag tgaaaaattt atcaaagctg ccattggctg tggtattgta 1260 gaaagcatac taaactgggt gaagtttaag gcccaagtcc agttaaacaa gaagtgttca 1320 gctgtaaaac ataatagaat caagggaatt cccaaactcg atgatgccaa tgatgcaggg 1380 ggccgaaact ccactgagtg tacgcttatc ctgactgagg gagattcagc caaaactttg 1440 gctgtttcag gccttggtgt ggttgggaga gacaaatatg gggttttccc tcttagagga 1500 aaaatactca atgttcgaga agcttctcat aagcagatca tggaaaatgc tgagattaac 1560 aatatcatca agattgtggg tcttcagtac aagaaaaact atgaagatga agattcattg 1620 aagacgcttc gttatgggaa gataatgatt atgacagatc aggaccaaga tggttcccac 1680 atcaaaggct tgctgattaa ttttatccat cacaactggc cctctcttct gcgacatcgt 1740 tttctggagg aatttatcac tcccattgta aaggtatcta aaaacaagca agaaatggca 1800 ttttacagcc ttcctgaatt tgaagagtgg aagagttcta ctccaaatca taaaaaatgg 1860 aaagtcaaat attacaaagg tttgggcacc agcacatcaa aggaagctaa agaatacttt 1920 gcagatatga aaagacatcg tatccagttc aaatattctg gtcctgaaga tgatgctgct 1980 atcagcctgg cctttagcaa aaaacagata gatgatcgaa aggaatggtt aactaatttc 2040 atggaggata gaagacaacg aaagttactt gggcttcctg aggattactt gtatggacaa 2100 actaccacat atctgacata taatgacttc atcaacaagg aacttatctt gttctcaaat 2160 tctgataacg agagatctat cccttctatg gtggatggtt tgaaaccagg tcagagaaag 2220 gttttgttta cttgcttcaa acggaatgac aagcgagaag taaaggttgc ccaattagct 2280 ggatcagtgg ctgaaatgtc ttcttatcat catggtgaga tgtcactaat gatgaccatt 2340 atcaatttgg ctcagaattt tgtgggtagc aataatctaa acctcttgca gcccattggt 2400 cagtttggta ccaggctaca tggtggcaag gattctgcta gtccacgata catctttaca 2460 atgctcagct ctttggctcg attgttattt ccaccaaaag atgatcacac gttgaagttt 2520 ttatatgatg acaaccagcg tgttgagcct gaatggtaca ttcctattat tcccatggtg 2580 ctgataaatg gtgctgaagg aatcggtact gggtggtcct gcaaaatccc caactttgat 2640 gtgcgtgaaa ttgtaaataa catcaggcgt ttgatggatg gagaagaacc tttgccaatg 2700 cttccaagtt acaagaactt caagggtact attgaagaac tggctccaaa tcaatatgtg 2760 attagtggtg aagtagctat tcttaattct acaaccattg aaatctcaga gcttcccgtc 2820 agaacatgga cccagacata caaagaacaa gttctagaac ccatgttgaa tggcaccgag 2880 aagacacctc ctctcataac agactatagg gaataccata cagataccac tgtgaaattt 2940 gttgtgaaga tgactgaaga aaaactggca gaggcagaga gagttggact acacaaagtc 3000 ttcaaactcc aaactagtct cacatgcaac tctatggtgc tttttgacca cgtaggctgt 3060 ttaaagaaat atgacacggt gttggatatt ctaagagact tttttgaact cagacttaaa 3120 tattatggat taagaaaaga atggctccta ggaatgcttg gtgctgaatc tgctaaactg 3180 aataatcagg ctcgctttat cttagagaaa atagatggca aaataatcat tgaaaataag 3240 cctaagaaag aattaattaa agttctgatt cagaggggat atgattcgga tcctgtgaag 3300 gcctggaaag aagcccagca aaaggttcca gatgaagaag aaaatgaaga gagtgacaac 3360 gaaaaggaaa ctgaaaagag tgactccgta acagattctg gaccaacctt caactatctt 3420 cttgatatgc ccctttggta tttaaccaag gaaaagaaag atgaactctg caggctaaga 3480 aatgaaaaag aacaagagct ggacacatta aaaagaaaga gtccatcaga tttgtggaaa 3540 gaagacttgg ctacatttat tgaagaattg gaggctgttg aagccaagga aaaacaagat 3600 gaacaagtcg gacttcctgg gaaagggggg aaggccaagg ggaaaaaaac acaaatggct 3660 gaagttttgc cttctccgcg tggtcaaaga gtcattccac gaataaccat agaaatgaaa 3720 gcagaggcag aaaagaaaaa taaaaagaaa attaagaatg aaaatactga aggaagccct 3780 caagaagatg gtgtggaact agaaggccta aaacaaagat tagaaaagaa acagaaaaga 3840 gaaccaggta caaagacaaa gaaacaaact acattggcat ttaagccaat caaaaaagga 3900 aagaagagaa atccctggcc tgattcagaa tcagatagga gcagtgacga aagtaatttt 3960 gatgtccctc cacgagaaac agagccacgg agagcagcaa caaaaacaaa attcacaatg 4020 gatttggatt cagatgaaga tttctcagat tttgatgaaa aaactgatga tgaagatttt 4080 gtcccatcag atgctagtcc acctaagacc aaaacttccc caaaacttag taacaaagaa 4140 ctgaaaccac agaaaagtgt cgtgtcagac cttgaagctg atgatgttaa gggcagtgta 4200 ccactgtctt caagccctcc tgctacacat ttcccagatg aaactgaaat tacaaaccca 4260 gttcctaaaa agaatgtgac agtgaagaag acagcagcaa aaagtcagtc ttccacctcc 4320 actaccggtg ccaaaaaaag ggctgcccca aaaggaacta aaagggatcc agctttgaat 4380 tctggtgtct ctcaaaagcc tgatcctgcc aaaaccaaga atcgccgcaa aaggaagcca 4440 tccacttctg atgattctga ctctaatttt gagaaaattg tttcgaaagc agtcacaagc 4500 aagaaatcca agggggagag tgatgacttc catatggact ttgactcagc tgtggctcct 4560 cgggcaaaat ctgtacgggc aaagaaacct ataaagtacc tggaagagtc agatgaagat 4620 gatctgtttt aaaatgtgag gcgattattt taagtaatta tcttaccaag cccaagactg 4680 gttttaaagt tacctgaagc tcttaacttc ctcccctctg aatttagttt ggggaaggtg 4740 tttttagtac aagacatcaa agtgaagtaa agcccaagtg ttctttagct tt 4792 <210> 157 <211> 3622 <212> DNA <213> HUMAN <400> 157 cccggggagg ggaccgggga acagagggcc gagaggcgtg cggcaggggg gagggtagga 60 gaaagaaggg cccgactgta ggagggcagc ggagcattac ctcatcccgt gagcctccgc 120 gggcccagag aagaatcttc tagggtggag tctccatggt gacgggcggg cccgcccccc 180 tgagagcgac gcgagccaat gggaaggcct tggggtgaca tcatgggcta tttttagggg 240 ttgactggta gcagataagt gttgagctcg ggctggataa gggctcagag ttgcactgag 300 tgtggctgaa gcagcgaggc gggagtggag gtgcgcggag tcaggcagac agacagacac 360 agccagccag ccaggtcggc agtatagtcc gaactgcaaa tcttattttc ttttcacctt 420 ctctctaact gcccagagct agcgcctgtg gctcccgggc tggtggttcg ggagtgtcca 480 gagagccttg tctccagccg gccccgggag gagagccctg ctgcccaggc gctgttgaca 540 gcggcggaaa gcagcggtac cccacgcgcc cgccggggga cgtcggcgag cggctgcagc 600 agcaaagaac tttcccggcg gggaggaccg gagacaagtg gcagagtccc ggagcgaact 660 tttgcaagcc tttcctgcgt cttaggcttc tccacggcgg taaagaccag aaggcggcgg 720 agagccacgc aagagaagaa ggacgtgcgc tcagcttcgc tcgcaccggt tgttgaactt 780 gggcgagcgc gagccgcggc tgccgggcgc cccctccccc tagcagcgga ggaggggaca 840 agtcgtcgga gtccgggcgg ccaagacccg ccgccggccg gccactgcag ggtccgcact 900 gatccgctcc gcggggagag ccgctgctct gggaagtgag ttcgcctgcg gactccgagg 960 aaccgctgcg cccgaagagc gctcagtgag tgaccgcgac ttttcaaagc cgggtagcgc 1020 gcgcgagtcg acaagtaaga gtgcgggagg catcttaatt aaccctgcgc tccctggagc 1080 gagctggtga ggagggcgca gcggggacga cagccagcgg gtgcgtgcgc tcttagagaa 1140 actttccctg tcaaaggctc cggggggcgc gggtgtcccc cgcttgccag agccctgttg 1200 cggccccgaa acttgtgcgc gcacgccaaa ctaacctcac gtgaagtgac ggactgttct 1260 atgactgcaa agatggaaac gaccttctat gacgatgccc tcaacgcctc gttcctcccg 1320 tccgagagcg gaccttatgg ctacagtaac cccaagatcc tgaaacagag catgaccctg 1380 aacctggccg acccagtggg gagcctgaag ccgcacctcc gcgccaagaa ctcggacctc 1440 ctcacctcgc ccgacgtggg gctgctcaag ctggcgtcgc ccgagctgga gcgcctgata 1500 atccagtcca gcaacgggca catcaccacc acgccgaccc ccacccagtt cctgtgcccc 1560 aagaacgtga cagatgagca ggaggggttc gccgagggct tcgtgcgcgc cctggccgaa 1620 ctgcacagcc agaacacgct gcccagcgtc acgtcggcgg cgcagccggt caacggggca 1680 ggcatggtgg ctcccgcggt agcctcggtg gcagggggca gcggcagcgg cggcttcagc 1740 gccagcctgc acagcgagcc gccggtctac gcaaacctca gcaacttcaa cccaggcgcg 1800 ctgagcagcg gcggcggggc gccctcctac ggcgcggccg gcctggcctt tcccgcgcaa 1860 ccccagcagc agcagcagcc gccgcaccac ctgccccagc agatgcccgt gcagcacccg 1920 cggctgcagg ccctgaagga ggagcctcag acagtgcccg agatgcccgg cgagacaccg 1980 cccctgtccc ccatcgacat ggagtcccag gagcggatca aggcggagag gaagcgcatg 2040 aggaaccgca tcgctgcctc caagtgccga aaaaggaagc tggagagaat cgcccggctg 2100 gaggaaaaag tgaaaacctt gaaagctcag aactcggagc tggcgtccac ggccaacatg 2160 ctcagggaac aggtggcaca gcttaaacag aaagtcatga accacgttaa cagtgggtgc 2220 caactcatgc taacgcagca gttgcaaaca ttttgaagag agaccgtcgg gggctgaggg 2280 gcaacgaaga aaaaaaataa cacagagaga cagacttgag aacttgacaa gttgcgacgg 2340 agagaaaaaa gaagtgtccg agaactaaag ccaagggtat ccaagttgga ctgggttcgg 2400 tctgacggcg cccccagtgt gcacgagtgg gaaggacttg gtcgcgccct cccttggcgt 2460 ggagccaggg agcggccgcc tgcgggctgc cccgctttgc ggacgggctg tccccgcgcg 2520 aacggaacgt tggactttcg ttaacattga ccaagaactg catggaccta acattcgatc 2580 tcattcagta ttaaaggggg gagggggagg gggttacaaa ctgcaataga gactgtagat 2640 tgcttctgta gtactcctta agaacacaaa gcggggggag ggttggggag gggcggcagg 2700 agggaggttt gtgagagcga ggctgagcct acagatgaac tctttctggc ctgctttcgt 2760 taactgtgta tgtacatata tatatttttt aatttgatta aagctgatta ctgtcaataa 2820 acagcttcat gcctttgtaa gttatttctt gtttgtttgt ttgggtatcc tgcccagtgt 2880 tgtttgtaaa taagagattt ggagcactct gagtttacca tttgtaataa agtatataat 2940 ttttttatgt tttgtttctg aaaattccag aaaggatatt taagaaaata caataaacta 3000 ttggaaagta ctcccctaac ctcttttctg catcatctgt agatcctagt ctatctaggt 3060 ggagttgaaa gagttaagaa tgctcgataa aatcactctc agtgcttctt actattaagc 3120 agtaaaaact gttctctatt agacttagaa ataaatgtac ctgatgtacc tgatgctatg 3180 tcaggcttca tactccacgc tcccccagcg tatctatatg gaattgctta ccaaaggcta 3240 gtgcgatgtt tcaggaggct ggaggaaggg gggttgcagt ggagagggac agcccactga 3300 gaagtcaaac atttcaaagt ttggattgca tcaagtggca tgtgctgtga ccatttataa 3360 tgttagaaat tttacaatag gtgcttattc tcaaagcagg aattggtggc agattttaca 3420 aaagatgtat ccttccaatt tggaatcttc tctttgacaa ttcctagata aaaagatggc 3480 ctttgtctta tgaatattta taacagcatt ctgtcacaat aaatgtattc aaataccaat 3540 aacagatctt gaattgcttc cctttactac ttttttgttc ccaagttata tactgaagtt 3600 tttattttta gttgctgagg tt 3622 <210> 158 <211> 1596 <212> DNA <213> HUMAN <400> 158 tgtcggggac ggtaaccggg acccgtgctc tgctcctgtc gccttcgcct cctgaatccc 60 tagccatatg cgtgagtgca tctccatcca cgttggccag gctggtgtcc agattggcaa 120 tgcctgctgg gagctctact gcctggaaca cggcatccag cccgatggcc agatgccaag 180 tgacaagacc attgggggag gagatgactc cttcaacacc ttcttcagtg agacgggcgc 240 tggcaagcac gtgccccggg ctgtgtttgt agacttggaa cccacagtca ttgatgaagt 300 tcgcactggc acctaccgcc agctcttcca ccctgagcag ctcatcacag gcaaggaaga 360 tgctgccaat aactatgccc gagggcacta caccattggc aaggagatca ttgaccttgt 420 gttggaccga attcgcaagc tggctgacca gtgcacccgt cttcagggct tcttggtttt 480 ccacagcttt ggtgggggaa ctggttctgg gttcacctcc ctgctcatgg aacgcctgtc 540 agttgattat ggcaagaaat ccaagctgga gttctccatt tacccggcac cccaggtttc 600 cacagctgta gttgagccct acaactccat cctcaccacc cacaccaccc tggagcactc 660 tgattgtgcc ttcatggtag acaatgaggc catctatgac atctgtcgta gaaacctcga 720 tatcgagcgc ccaacctaca ctaaccttaa ccgccttatt agccagattg tgtcctccat 780 cactgcttcc ctgagatttg atggagccct gaatgttgac ctgacagaat tccagaccaa 840 cctggtcccc tacccccgca tccacttccc tctggccaca tatgcccctg tcatctctgc 900 tgagaaagcc taccatgaac agctttctgt agcagacatc accaatgctt gctttgagcc 960 agccaaccag atggtgaaat gtgaccctgg ccatggtaaa tacatggctt gctgcctgtt 1020 gtaccgtggt gacgtggttc ccaaagatgt caatgctgcc attgccacca tcaaaaccaa 1080 gcgcacgatc cagtttgtgg attggtgccc cactggcttc aaggttggca tcaactacca 1140 gcctcccact gtggtgcctg gtggagacct ggccaaggta cagagagctg tgtgcatgct 1200 gagcaacacc acagccattg ctgaggcctg ggctcgcctg gaccacaagt ttgacctgat 1260 gtatgccaag cgtgcctttg ttcactggta cgtgggtgag gggatggagg aaggcgagtt 1320 ttcagaggcc cgtgaagata tggctgccct tgagaaggat tatgaggagg ttggtgtgga 1380 ttctgttgaa ggagagggtg aggaagaagg agaggaatac taattatcca ttccttttgg 1440 ccctgcagca tgtcatgctc ccagaatttc agcttcagct taactgacag atgttaaagc 1500 tttctggtta gattgttttc acttggtgat catgtctttt ccatgtgtac ctgtaatatt 1560 tttccatcat atctcaaagt aaagtcatta acatca 1596 <210> 159 <211> 1848 <212> DNA <213> HUMAN <400> 159 aaaggagcag gggcctttgg ctactttgag gtcacacatg acattaccaa atactccaag 60 gcaaaggtat ttgagcatat tggaaagaag actcccatcg cagttcggtt ctccactgtt 120 gctggagaat cgggttcagc tgacacagtt cgggaccctc gtgggtttgc agtgaaattt 180 tacacagaag atggtaactg ggatctcgtt ggaaataaca cccccatttt cttcatcagg 240 gatcccatat tgtttccatc ttttatccac agccaaaaga gaaatcctca gacacatctg 300 aaggatccgg acatggtctg ggacttctgg agcctacgtc ctgagtctct gcatcaggtt 360 tctttcttgt tcagtgatcg ggggattcca gatggacatc gccacatgaa tggatatgga 420 tcacatactt tcaagctggt taatgcaaat ggggaggcag tttattgcaa attccattat 480 aagactgacc agggcatcaa aaacctttct gttgaagatg cggcgagact ttcccaggaa 540 gatcctgact atggcatccg ggatcttttt aacgccattg ccacaggaaa gtacccctcc 600 tggacttttt acatccaggt catgacattt aatcaggcag aaacttttcc atttaatcca 660 ttcgatctca ccaaggtgag tcagtaaaca actatattgt tttctttttt aagtctcttc 720 ttacctaatt agaaaaaaaa tctagtcaaa caattataat aatggggaag tcatatacaa 780 aatacagagg gtaccacttc agagtgtcct aagctgtgaa tgagtgctta ccagcatctt 840 acttccacgt tcctgtttgt catttcattg agtatgtgta tgtggcttca tatattgtta 900 ttaacaggga acagattatg aaaagctgat gtactttttc ctggggaaac tgtcagtatt 960 taccacttac tattgtgaaa gatttaacta aggcactcat cttaaattct tatgttttat 1020 tggatttaaa aattattttc attggcttga ttgtatttga aatctggtat ttttgtgggt 1080 agctttgatt tccttcagtt gattgcctgg taattgtgaa tatgacatca ttttcaggtt 1140 tggcctcaca aggactaccc tctcatccca gttggtaaac tggtcttaaa ccggaatcca 1200 gttaattact ttgctgaggt tgaacagata gccttcgacc caagcaacat gccacctggc 1260 attgaggcca gtcctgacaa aatgcttcag ggccgccttt ttgcctatcc tgacactcac 1320 cgccatcgcc tgggacccaa ttatcttcat atacctgtga actgtcccta ccgtgctcga 1380 gtggccaact accaacgtga cggcccgatg tgcatgcagg acaatcaggg tggtgctcca 1440 aattactacc ccaacagctt tggtgctccg gaacaacagc cttctgcctt ggagcacagc 1500 atccaatatt ctggagaagt gcggagattc aacactgcca atgatgataa cgttactcag 1560 gtgcgggcat tctatgtgaa cgtgctgaat gaggaacaga ggaaacgtct gtgtgagaac 1620 attgccggcc acctgaagga tgcacaaatt ttcatccaga agaaagcggt caagaacttc 1680 actgaggtcc accctgacta cgggagccac atccaggctc ttctggacaa gtacaatgct 1740 gagaagccta agaatgcgat tcacaccttt gtgcagtccg gatctcactt ggcggcaagg 1800 gagaaggcaa atctgtgagg ccggggccct gcacctgtgc atgaagct 1848 <210> 160 <211> 1560 <212> DNA <213> HUMAN <400> 160 atatgtggcc aaatcattcc ttggaatttc ccgttggtta tgctcatttg gaagataggg 60 cctgcactga gctgtggaaa cacagtggtt gtcaaaccag cagagcaaac tcctctcact 120 gctctccacg tggcatcttt aataaaagag gcagggtttc ctcctggagt agtgaatatt 180 gttcctggtt atgggcctac agcaggggca gccatttctt ctcacatgga tatagacaaa 240 gtagccttca caggatcaac agaggttggc aagttgatca aagaagctgc cgggaaaagc 300 aatctgaaga gggtgaccct ggagcttgga ggaaagagcc cttgcattgt gttagctgat 360 gccgacttgg acaatgctgt tgaatttgca caccatgggg tattctacca ccagggccag 420 tgttgtatag ccgcatccag gatttttgtg gaagaatcaa tttatgatga gtttgttcga 480 aggagtgttg agcgggctaa gaagtatatc cttggaaatc ctctgacccc aggagtcact 540 caaggccctc agattgacaa ggaacaatat gataaaatac ttgacctcat tgagagtggg 600 aagaaagaag gggccaaact ggaatgtgga ggaggcccgt gggggaataa aggctacttt 660 gtccagccca cagtgttctc taatgttaca gatgagatgc gcattgccaa agaggagatt 720 tttggaccag tgcagcaaat catgaagttt aaatctttag atgacgtgat caaaagagca 780 aacaatactt tctatggctt atcagcagga gtgtttacca aagacattga taaagccata 840 acaatctcct ctgctctgca ggcaggaaca gtgtgggtga attgctatgg cgtggtaagt 900 gcccagtgcc cctttggtgg attcaagatg tctggaaatg gaagagaact gggagagtac 960 ggtttccatg aatatacaga ggtcaaaaca gtcacagtga aaatctctca gaagaactca 1020 taaagaaaat acaagagtgg agagaagctc ttcaatagct aagcatctcc ttacagtcac 1080 taatatagta gattttaaag acaaaatttt tcttttcttg atttttttta aacataagct 1140 aaatcatatt agtattaata ctacccatag aaaacttgac atgtagcttc ttctgaaaga 1200 attatttgcc ttctgaaatg tgacccccaa gtcctatcct aaataaaaaa agacaaattc 1260 ggatgtatga tctctctagc tttgtcatag ttatgtgatt ttcctttgta gctacttttg 1320 caggataata attttataga aaaggaacag ttgcatttag cttctttccc ttagtgactc 1380 ttgaagtact taacatacac gttaactgca gagtaaattg ctctgttccc agtagttata 1440 aagtccttgg actgttttga aaagtttcct aggatgtcat gtctgcttgt caaaagaaat 1500 aatccctgta atatttagct gtaaactgaa tataaagctt aataaaaaca accttgcata 1560 <210> 161 <211> 1987 <212> DNA <213> HUMAN <400> 161 ctcgagagct ccgccatggc cgctctcacc cgggaccccc agttccagaa gctgcagcaa 60 tggtaccgcg agcaccgctc cgagctgaac ctgcgccgcc tcttcgatgc caacaaggac 120 cgcttcaacc acttcagctt gaccctcaac accaaccatg ggcatatcct ggtggattac 180 tccaagaacc tggtgacgga ggacgtgatg cggatgctgg tggacttggc caagtccagg 240 ggcgtggagg ccgcccggga gcggatgttc aatggtgaga agatcaacta caccgagggt 300 cgagccgtgc tgcacgtggc tctgcggaac cggtcaaaca cacccatcct ggtagacggc 360 aaggatgtga tgccagaggt caacaaggtt ctggacaaga tgaagtcttt ctgccagcgt 420 gtccggagcg gtgactggaa ggggtacaca ggcaagacca tcacggacgt catcaacatt 480 ggcattgtcg gctccgacct gggacccctc atggtgactg aagcccttaa gccatactct 540 tcaggaggtc cccgcgtctg gtatgtctcc aacattgatg gaactcacat tgccaaaacc 600 ctggcccagc tgaacccgga gtcctccctg ttcatcattg cctccaagac ctttactacc 660 caggagacca tcacgaatgc agagacggcg aaggagtggt ttctccaggc ggccaaggat 720 ccttctgcag tggcgaagca ctttgttgcc ctgtctacta acacaaccaa agtgaaggag 780 tttggaattg accctcaaaa catgttcgag ttctgggatt gggtgggagg acgctactcg 840 ctgtggtcgg ccatcggact ctccattgcc ctgcacgtgg gttttgacaa cttcgagcag 900 ctgctctcgg gggctcactg gatggaccag cacttccgca cgacgcccct ggagaagaac 960 gcccccgtct tgctggccct gctgggtatc tggtacatca actgctttgg gtgtgagaca 1020 cacgccatgc tgccctatga ccagtacctg caccgctttg ctgcgtactt ccagcagggc 1080 gacatggagt ccaatgggaa atacatcacc aaatctggaa cccgtgtgga ccaccagaca 1140 ggccccattg tgtgggggga gccagggacc aatggccagc atgcttttta ccagctcatc 1200 caccaaggca ccaagatgat accctgtgac ttcctcatcc cggtccagac ccagcacccc 1260 atacggaagg gtctgcatca caagatcctc ctggccaact tcttggccca gacagaggcc 1320 ctgatgaggg gaaaatcgac ggaggaggcc cgaaaggagc tccaggctgc gggcaagagt 1380 ccagaggacc ttgagaggct gctgccacat aaggtctttg aaggaaatcg cccaaccaac 1440 tctattgtgt tcaccaagct cacaccattc atgcttggag ccttggtcgc catgtatgag 1500 cacaagatct tcgttcaggg catcatctgg gacatcaaca gctttgacca gtggggagtg 1560 gagctgggaa agcagctggc taagaaaata gagcctgagc ttgatggcag tgctcaagtg 1620 acctctcacg acgcttctac caatgggctc atcaacttca tcaagcagca gcgcgaggcc 1680 agagtccaat aaactcgtgc tcatctgcag cctcctctgt gactcccctt tctcttctcg 1740 tccctcctcc ccggagccgg cactgcatgt tcctggacac cacccagagc accctctggt 1800 tgtgggcttg gaccacgagc ccttagcagg gaaggctggt ctcccccagc ctaaccccca 1860 gcccctccat gtctatgctc cctctgtgtt agaattggct gaagtgtttt tgtgcagctg 1920 acttttctga cccatgttca cgttgttcac atcccatgta gaaaaacaaa gatgccacgg 1980 aggaggt 1987 <210> 162 <211> 1662 <212> DNA <213> HUMAN <400> 162 caagagctcc agcaaagact ttcactgtag cttgacttga cctgagatta actagggaat 60 cttgagaata aagatgagct ctgaaaattg tttcgtagca gagaacagct ctttgcatcc 120 ggagagtgga caagaaaatg atgccaccag tccccatttc tcaacacgtc atgaagggtc 180 cttccaagtt cctgtcctgt gtgctgtaat gaatgtggtc ttcatcacca ttttaatcat 240 agctctcatt gccttatcag tgggccaata caattgtcca ggccaataca cattctcaat 300 gccatcagac agccatgttt cttcatgctc tgaggactgg gttggctacc agaggaaatg 360 ctactttatt tctactgtga agaggagctg gacttcagcc caaaatgctt gttctgaaca 420 tggtgctact cttgctgtca ttgattctga aaaggacatg aactttctaa aacgatacgc 480 aggtagagag gaacactggg ttggactgaa aaaggaacct ggtcacccat ggaagtggtc 540 aaatggcaaa gaatttaaca actggttcaa cgttacaggg tctgacaagt gtgtttttct 600 gaaaaacaca gaggtcagca gcatggaatg tgagaagaat ttatactgga tatgtaacaa 660 accttacaaa taataaggaa acgtgttcac ttattgacta ttatagaatg gaactcaagg 720 aaatctgtgt cagtggatgc tgctctgtgg tccgaagtct tccatagaga ctttgtgaaa 780 aaaaatttta tagtgtcttg ggaattttct tccaaacaga actatggaaa aaaaggaaga 840 aattccagga aaatctgcac ttgtggcttt tattgccatg agctagaagc atcacaggtt 900 gaccaataac catgcccaag aatgagaaga atgactatgc aacctttgga tgcactttat 960 attattttga atccagaaat aatgaaataa ctaggcgtgg acttactatt aattgctgaa 1020 tgactaccaa cagtgagagc ccttcatgca tttgcactat tggaaggagt tagatgttgg 1080 tactagatac tgaatgtaaa caaaggaatt atggctggta acatagtttt tagtctaatt 1140 gaatccctta aactcaggga gcatttataa atggcaaatg cttatgaaac taagatttgt 1200 aatatttctc tctttttaga gaaatttgcc aatttacttt gttatttttc cccaaaaaga 1260 atgggatgat cgtgtattta tttttttact tcctcagctg tagacaggtc cttttcgatg 1320 gtacatattt ctttgccttt ataatctttt atacagtgtc ttacagagaa aagacataag 1380 caaagactat gaggaatatt tgcaagacat agaatagtgt tggaaaatgt gcaatatgtg 1440 atgtggcaaa tctctattag gaaatattct gtaatcttca gacctagaat aatactagtc 1500 ttataatagg tttgtgactt tcctaaatca attctattac gtgcaatact tcaatacttc 1560 atttaaaata tttttatgtg caataaaatg tatttgtttg tattttgtgt tcagtacaat 1620 tataagctgt ttttatatat gtgaaataaa agtagaataa ac 1662 <210> 163 <211> 398 <212> DNA <213> HUMAN <400> 163 gatgctgggg ctggtcctgg ccttgctgtc ctccagctct gctgaggagt acgtgggcct 60 gtctgcaaac cagtgtgccg tgccggccaa ggacagggtg gactgcggct acccccatgt 120 cacccccaag gagtgcaaca accggggctg ctgctttgac tccaggatcc ctggagtgcc 180 ttggtgtttc aagcccctga ctaggaagac agaatgcacc ttctgaggca cctccagctg 240 cccctgggat gcaggctgag cacccttgcc cggctgtgat tgctgccagg cactgttcat 300 ctcagttttt ctgtcccttt gctcccggca agctttctgc tgaaagttca tatctggagc 360 ctgatgtctt aacgaataaa ggtcccatgc tccacccg 398 <210> 164 <211> 1644 <212> DNA <213> HUMAN <400> 164 ggcgagatgg cggccaccga gggggtcggg gaggctgcgc aagggggcga gcccgggcag 60 ccggcgcaac ccccgcccca gccgcaccca ccgccgcccc agcagcagca caaggaagag 120 atggcggccg aggctgggga agccgtggcg tcccccatgg acgacgggtt tgtgagcctg 180 gactcgccct cctatgtcct gtacagggac agagcagaat gggctgatat agatccggtg 240 ccgcagaatg atggccccaa tcccgtggtc cagatcattt atagtgacaa atttagagat 300 gtttatgatt acttccgagc tgtcctgcag cgtgatgaaa gaagtgaacg agcttttaag 360 ctaacccggg atgctattga gttaaatgca gccaattata cagtgtggca tttccggaga 420 gttcttttga agtcacttca gaaggatcta catgaggaaa tgaactacat cactgcaata 480 attgaggagc agcccaaaaa ctatcaagtt tggcatcata ggcgagtatt agtggaatgg 540 ctaagagatc catctcagga gcttgaattt attgctgata ttcttaatca ggatgcaaag 600 aattatcatg cctggcagca tcgacaatgg gttattcagg aatttaaact ttgggataat 660 gagctgcagt atgtggacca acttctgaaa gaggatgtga gaaataactc tgtctggaac 720 caaagatact tcgttatttc taacaccact ggctacaatg atcgtgctgt attggagaga 780 gaagtccaat acactctgga aatgattaaa ctagtaccac ataatgaaag tgcatggaac 840 tatttgaaag ggattttgca ggatcgtggt ctttccaaat atcctaatct gttaaatcaa 900 ttacttgatt tacaaccaag tcatagttcc ccctacctaa ttgcctttct tgtggatatc 960 tatgaagaca tgctagaaaa tcagtgtgac aataaggaag acattcttaa taaagcatta 1020 gagttatgtg aaatcctagc taaagaaaag gacactataa gaaaggaata ttggagatac 1080 attggaagat cccttcaaag caaacacagc acagaaaatg actcaccaac aaatgtacag 1140 caataacacc atccagaaga acttgatgga atgcttttat tttttattaa gggaccctgc 1200 aggagtttca cacgagagtg gtccttccct ttgcctgtgg tgtaaaagtg catcacacag 1260 gtattgcttt ttaacaagaa ctgatgctcc ttgggtgctg ctgctactca gactagctct 1320 aagtaatgtg attcttctaa agcaaagtca ttggatggga ggaggaagaa aaagtcccat 1380 aaaggaactt ttgtagtctt atcaacatat aatctaatcc cttagcatca gctcctccct 1440 cagtggtaca tgcgtcaaga tttgtagcag taataactgc aggtcacttg tatgtaatgg 1500 atgtgaggta gccgaagttt ggttcagtaa gcagggaata cagtcgttcc atcagagctg 1560 gtctgcacac tcacattatc ttgctatcac tgtaaccaac taatgccaaa agaacggttt 1620 tgtaataaaa ttatagctgt atct 1644 <210> 165 <211> 6305 <212> DNA <213> HUMAN <400> 165 gaattcctgg gctcagaggt cctcccacct tagccttctg agtagctagg actacagaca 60 ccagctacca catgaggctt tgtagaaatg gggtcttact atgttgccca ggctgatttt 120 gaactcctgg tctcaagcaa tctttccacc ttagccttcc aaagtgctgg aattacagga 180 gtgggccact gcacctggct ctattaacat tttttatttg ctttatcaca tatttatcaa 240 tccatctcac ttttaaatat cttttaaaat tacaaatatc agtacatttt acatctaaac 300 ccttcagaag cttaacattg actggagttc agtatttatt tccccatttc ttttctggcc 360 tgaggaaggc aaattttaca tacaaatctc aagtcagtac tctttttttt ttttgagacg 420 gagtcttgct ctgttgccca ggctggagtc cagtggtgtg atcttggctc actgcaacct 480 ctgccttctg ggtacaagcg attctcctgt ctcagcctcc caagtagctg ggactacagg 540 tttgtgccac catatccagc taatttttgt atttttaatg gagaaggggt ttcaccatgt 600 tggccaggct ggtctcaaac tcttgacctc aagtgatcca cctgccttgg tctcctaaag 660 tgctgggatt ataggtgtga gccatctcgc ctggcctaat actgttttgt ttgtttgttt 720 ttgtttttaa gacagagtct tgttcttgtc acccaggctg gagtgcaatg gcatgatttc 780 ggctcactgc aacttccgcc tcctgggttc aagtgattct cctgcctcag cctcccaagt 840 agctggaatt aaaggtgcct accaccacgc cccgctaatt tttatatttt tagtagagat 900 ggggtttcac catgttgatc aggctgctct cgagctcctt acctcagatg atccaccttc 960 cttggcctcc caaagtgctg gtattatagg caagagccac tgcgcccagc cccagtattc 1020 agtttttaaa ctgtcttgtt atcaaggctc tggagccaga tgcctgggtt caaattctgg 1080 ttctgccact gactctgtga gctccataag tttcttaacc tctctgtacc tcagtttcct 1140 cttagggttt ttgtcaggat tataattatt ggctgggcat gatggctcat gcttgtaatc 1200 ccagcacttt aggaggccaa cacgggcaga tcacgtgagt ccaggagttt gagcccagcc 1260 tgggcaatgt ggcaaaaatc catctctaca aaaaatgcaa aaattagctg ggcatggtgg 1320 catgtgccta tagtcccagc tattcaggag gctgaggtag gtgaatccat agatcctggg 1380 aggtcaaggc tgcagtgagc catgatcctg ccattgcatt ccagtctggg tgacatagcg 1440 agaccctgtc tcaaaaaaaa aaattattaa agtgtgtaaa tcagtggcat aaacatgtta 1500 agtgcatttt gtgggtcagc tatattatta ttagtattac ggaaacacat agagatgtta 1560 ccaagaaggg gagatgattg gagccacttc cagcttcctt ggacctggtc tttcttccct 1620 tgactctttt tttttttttt tttttttttt tgagagagag agtctcagcc tgttgcccag 1680 gctggagtgc aatggtgcaa tcttggctca ctgcaacctc tgcctcccag gtttaagtga 1740 ttctcctgcc tcagcctcct gtgtagctgg aattacaggc gcgtgccacc acgcccggct 1800 aactttttgt atctttagta gagacagggt ttcaccatgt tggccaggct ggtctcgaac 1860 tcctgacctc aagtgatcca cctgcctcag cctcccaaag tgttgggatt acaggtgtaa 1920 gccactaccc cggctactcc cttgactctt aaccactcat gctgcctaca tctaccattc 1980 atgtggtcct tgctgctttg ttttggttat tcctgcattt atttgtcctt ttattcattt 2040 atgtataaac atttagtaag cacctactaa tggatagggc tcattgtaga cttggaagct 2100 ctctgagggt gggagtatgc ctcgtccatc tgtctttact ttttgtagca agggaggtaa 2160 agctccattt ccatccctcc ttagtgagtc agtagtcagt ggtgaggcta aggcttacct 2220 ctccctttct cactcagcac agggggctgg agatgagcaa gggaacggga ggaggtcagc 2280 ccagtatggg aatcagttct tctcagggaa cccagacatc catccctcaa gattccagtc 2340 cttgtcctag tccggccctt gacctcagag acgggatcag ctcttcctcc agcacctacc 2400 ttgagggtat agaagaatgc aaaccacatt ggaaacctgg agatctgtgt tctcatttca 2460 gctctgctga ctggcttcct gcaagctacc ttccctccct gggcctcagt ttctctctct 2520 gctgagccag aagatgtcta aagacccctt tggttccacc ctgagagcct gtctccctaa 2580 cctcaacttc ttccccagtt cagagaaccc aggcatccag ctgccccacc ccagctctgg 2640 gtaaacagga agctgggtga ggggagcagg ggtgtgcgga aagtcccagc caggtgtgca 2700 ggtctacagg gagggggtgg gcccgtccct gaggtatgaa agccccctgc tctggctctg 2760 gttcagtctc aatgggggca ctggggctgg agggcagggg tgggaggctc caggggaggg 2820 gttccctcct gctagctgtg gcaggagcca cttctctggt gaccttgttg ctggcggtgc 2880 ctatcactgt cctggctgtg ctggccttag tgccccagga tcagggagga ctggtgagtg 2940 gctgcaacag gccctggtgg agagttgtat cttgcggatg cttggctccc tctggttgtg 3000 cctgtggtct tttgccccct ctggctcagc tggctcggct gtccctggtg gggatgtctt 3060 gtctctttgc tgactctctt tccatgttcc tgtgatgttg tgcttgtgtc ccgacataag 3120 ccccttgtgt ctcctctcct cttcccgagg tacatctgtt tctccgccca agtacctatg 3180 ccttgcttgt tctcccttct aaggaggtgt gtgttgggga tggtgctggt aggagaaacc 3240 ccaggcctgc agcttgggtc cactttcaga ggggtagggg tgacatgagc tgaatctgaa 3300 ctctgggcac tgtgacccca cccaaccagg taacggagac ggccgacccc ggggcacagg 3360 cccagcaagg actgggtaag agcagactgt ctctccttcc ccgcttcaga ccctcagggg 3420 ctcccagctc cctgctgcgt ccccagatac ctcttcctct aggaatccag gctccccatc 3480 cctgcgccct gttctctcaa gggtagcctg catgggtggc tgccctgccc ccaatcgtgg 3540 actctttgcc ccttccaggg tttcagaagc tgccagagga ggagccagaa acagatctca 3600 gccccgggct cccagctgcc cacctcatag gtaaggacct ccaagacctg aataagagtg 3660 taaataatcc gaaggttcca gttctgctcg cccagagtcc ttcggctcca tgattccagt 3720 gctcggtttc ccacccgctt cacgaccttt tgtcgctcgt gcccactctt acgctcgtcc 3780 ccgcagtgta gtttcttctt ccctccggtg caagcaaaag ccggcctgga ggtccccact 3840 acagcgttct gcaccccaca tccgtgttcc ctcggccccc aactcgcact catcccagaa 3900 acagcaccat ccctcctccc ccggcccggc tcggctcccg caggggctaa aagccgccac 3960 ttccccagaa gtcccaagcc tttaggatcg cattcccaag agcgcgtcgg cccgtgtctc 4020 cgcaggcgct ccgctgaagg ggcaggggct aggctgggag acgacgaagg aacaggcgtt 4080 tctgacgagc gggacgcagt tctcggacgc cgaggggctg gcgctcccgc aggacggcct 4140 ctattacctc tactgtctcg tcggctaccg gggccgggcg ccccctggcg gcggggaccc 4200 ccagggccgc tcggtcacgc tgcgcagctc tctgtaccgg gcggggggcg cctacgggcc 4260 gggcactccc gagctgctgc tcgagggcgc cgagacggtg actccagtgc tggacccggc 4320 caggagacaa gggtacgggc ctctctggta cacgagcgtg gggttcggcg gcctggtgca 4380 gctccggagg ggcgagaggg tgtacgtcaa catcagtcac cccgatatgg tggacttcgc 4440 gagagggaag accttctttg gggccgtgat ggtggggtga gggaatatga gtgcgtggtg 4500 cgagtgcgtg aatattgggg gcccggacgc ccaggacccc atggcagtgg gaaaaatgta 4560 ggagactgtt tggaaattga ttttgaacct gatgaaaata aagaatggaa agcttcagtg 4620 ctgccgataa agatgctgag ttgcgacaca cgtcttaatt cagggtgggt gcacgggtgc 4680 gggttaaata ttctcagtac tcttctggtt gcttgaaaca attcatcaca acacagtgta 4740 tggcctttgc tcctagggat gatggtctgc ctgtcccacc ccctccctgc ctctgaatgg 4800 ccaggcccca ccattagccc agttggaggg tgggaggaag ggggacttct caaactccga 4860 agcttctcta ggcatcctga ttttcagggc cacatggtcc caaccagact ctgcaccata 4920 ctcttttctc ttgggtaccc cccaacagtg agaggggtca ttacagagcc cagcaagcac 4980 cactcagaaa ggcccagcag cagagtaagc ccctatcatg acagaggaat gaagcctgga 5040 ggggccccgc acttctcccc ctagagctgc ctgaaggcct ctctgtctcc tacccgacag 5100 tcaactcttc tcctccaagg agcttaattc aaggctcatg gggtctgaag ggaggaggct 5160 gaaggagaaa gaaggggaga atattagaga gagatgggga tggcaggaag gagcctgtgg 5220 tgcctgaaaa caccaggaag ttctggggag gaggaaaaac cgatgcccca cttagggtgt 5280 cccatttagg gtgagacgga aaatcctcac ctttttttca cactttaggt cccccttccc 5340 aaaagtgagt aagtgtgggt gcttctggga tgagtaacag tgtcccccat tacttcatgg 5400 ctgactttca gccacaggct ggaggaggca gagggtgacc caaggcccta tctaggtcac 5460 cccaatgggt caccctaccc cctcagccta ccacatggtt ttctcctgcc tggcacccca 5520 gggctggagg taaagcctaa tttccgaact cagtgggggc tcccagtcta ggggggctca 5580 atttccgtct ccatatttgt ttttggaatt attatttttt tgagacaggg tctcgttctg 5640 tcacccagac gggggtacag tggcatgatc atagcttact gtaacctcaa actcctgggc 5700 ttgagtgatc ctcctgcctc agcctcctga ggagctagga ttacaggcat gcaccactac 5760 acctgactaa tctttaattt tttttctaga aacaaggtct tgctatgttg cacaggctgg 5820 tcttgaacta gtgggctcaa gtggtcctcc cacctcagcc tcccaaagtg ttgggataac 5880 aggcatgagc cactgcgccc cacccttatt tgtctttgac tctctccaga agagccttca 5940 tccagggagg gggtgctttt ctctttccgg attacccacc tctcacctct cccctccttc 6000 accacaaaga ccagtgggac caagccggca tgtgagtcct tcacccacat cttattccta 6060 tgtttcattc ttttttaaaa aatagagaca ggatctcact atgttgccca ggttgctctg 6120 gaactcctgg gttcaagcga tcctctcacc ttggccttgc aaagtggtag gattacaggt 6180 gcatgccacc acgtccggca gttcggttcc ttgttcttta ttgtcctcag tctcttcgat 6240 ttcacccact gagagaatgg aaggggatag aacagctgga aactggttga aggaagccag 6300 aattc 6305 <210> 166 <211> 3702 <212> DNA <213> HUMAN <400> 166 aattagagta gaagttgtcg gggtccgctc ttaggacgca gccgcctcat gggggtccag 60 gggctctgga agctgctgga gtgctccggg cggcaggtca gccccgaagc gctggaaggg 120 aagatcctgg ctgttgatat tagcatttgg ttaaaccaag cacttaaagg agtccgggat 180 cgccacggga actcaataga aaatcctcat cttctcactt tgtttcatcg gctctgcaaa 240 ctcttatttt ttcgaattcg tcctattttt gtgtttgatg gggatgctcc actattgaag 300 aaacagactt tggtgaagag aaggcagaga aaggacttag cgtccagtga ctccaggaaa 360 acgacagaga agcttctgaa aacatttttg aaaagacaag ccatcaaaac tgccttcaga 420 agcaaaagag atgaagcact acccagtctt acccaagttc gaagagaaaa cgacctctat 480 gttttgcctc ctttacaaga ggaagaaaaa cacagttcag aagaggaaga tgaaaaagaa 540 tggcaagaaa gaatgaatca aaaacaagca ttacaggaag agttctttca taatcctcaa 600 gcgatagata ttgagtctga ggacttcagc agcctgcccc ctgaagtaaa gcatgaaatc 660 ttgactgata tgaaagagtt caccaagcgc agaagaacat tatttgaagc aatgccagag 720 gagtctgatg acttttcaca gtaccaactc aaaggcttgc ttaaaaagaa ctatctgaac 780 cagcatatag aacatgtcca aaaggaagtg aatcagcaac attcaggaca catccgaagg 840 cagtatgaag atgaaggggg ctttctgaag gaggtagagt caaggagagt ggtctctgaa 900 gacacttcac attacatctt gataaaaggt attcaagcta agacagttgc agaagtggat 960 tcagagtctc ttccttcttc cagcaaaatg cacggcatgt cttttgacgt gaagtcatct 1020 ccatgtgaaa aactgaagac agagaaagag cctgatgcta cccctccttc tccaagaact 1080 ttactagcta tgcaagctgc cctgctggga agtagctcag aagaggagct ggagagtgaa 1140 aatcgaaggc aggcccgtgg gaggaacgca cctgctgctg tagacgaagg ctccatatca 1200 ccccggactc tttcagccat taagagagct cttgacgatg acgaagatgt aaaagtgtgt 1260 gctggggatg atgtgcagac gggagggcca ggagcagaag aaatgcgtat aaacagctcc 1320 accgagaaca gtgatgaagg acttaaagtg agagatggaa aaggaatacc gtttactgca 1380 acacttgcgt catctagtgt gaactctgca gaggagcacg tagccagcac taatgagggg 1440 agagagccca cagactcagt tccaaaagaa caaatgtcac ttgttcacgt ggggactgaa 1500 gcctttccga taagtgatga gtctatgatt aaggacagaa aagatcggct gcctctggag 1560 agtgcagtgg ttagacatag tgacgcacct gggctcccga atggaaggga actgacaccg 1620 gcatctccaa cttgtacaaa ttctgtgtca aagaatgaaa cacatgctga agtgcttgag 1680 cagcagaacg aactttgccc atatgagagt aaattcgatt cttctcttct ttcaagtgat 1740 gatgaaacaa aatgtaaacc gaattctgct tctgaagtca ttggccctgt cagtttgcaa 1800 gaaacaagta gcatagtaag tgtcccttca gaggcagtag ataatgtgga aaatgtggtg 1860 tcatttaatg ctaaagagca tgagaatttt ctggaaacca tccaagaaca gcagaccact 1920 gaatctgcag gccaggattt aatttccatt ccaaaggccg tggaaccaat ggaaattgac 1980 tcggaagaaa gtgaatctga tggaagtttc attgaagtgc aaagtgtgat tagtgatgag 2040 gaacttcaag cagaattccc tgaaacttcc aaacctccct cagaacaagg cgaagaggaa 2100 ctggtaggaa ctagggaggg agaagcccct gctgagtccg agagcctcct gagggacaac 2160 tctgagaggg acgacgtgga tggtgagcca caggaagctg agaaagatgc ggaagattcg 2220 ctccatgaat ggcaagatat taatttggag gagttggaaa ctctggagag caacctctta 2280 gcacagcaga attcactgaa agctcaaaaa cagcagcaag aacggatcgc tgctactgtc 2340 accggacaga tgttcctgga aagccaggaa ctcctgcgcc tgttcggcat tccctacatc 2400 caggctccca tggaagcaga ggcgcagtgc gccatcctgg acctgactga tcagacttcc 2460 ggaaccatca ctgatgacag tgatatctgg ctgtttggag cgcggcatgt ctatagaaac 2520 ttttttaata aaaataagtt tgtagaatat tatcaatatg tggactttca caatcaattg 2580 ggattggacc ggaataagtt aataaatttg gcttatttgc ttggaagtga ttataccgaa 2640 ggaataccaa ctgtgggttg tgtaaccgcc atggaaattc tcaatgaatt ccctgggcat 2700 ggcctggaac ctctcctaaa attctcagaa tggtggcatg aagctcaaaa aaatccaaag 2760 ataagaccta atcctcatga caccaaagtg aaaaaaaaat tacggacatt gcaactcacc 2820 cctggctttc ctaacccagc tgttgccgag gcctacctca aacccgtggt ggatgactcg 2880 aagggatcct ttctgtgggg gaaacctgat ctcgacaaaa ttagagaatt ttgtcagcgg 2940 tatttcggct ggaacagaac gaagacagat gaatctctgt ttcctgtatt aaagcaactc 3000 gatgcccagc agacacagct ccgaattgat tccttcttta gattagcaca acaggagaaa 3060 gaagatgcta aacgtattaa gagccagaga ctaaacagag ctgtgacatg tatgctaagg 3120 aaagagaaag aagcagcagc cagcgaaata gaagcagttt ctgttgccat ggagaaagaa 3180 tttgagctac ttgataaggc aaaacgaaaa acccagaaga gaggcataac aaatacctta 3240 gaagagtcat caagcctgaa aagaaagagg ctttcagatt ctaaacgaaa gaatacatgc 3300 ggtggatttt tgggggagac ctgcctctca gaatcatctg atggatcttc aagtgaagat 3360 gctgaaagtt catctttaat gaatgtacaa aggagaacag ctgcgaaaga gccaaaaacc 3420 agtgcttcag attcgcagaa ctcagtgaag gaagctcccg tgaagaatgg aggtgcgacc 3480 accagcagct ctagtgatag tgatgacgat ggagggaaag agaagatggt cctcgtgacc 3540 gccagatctg tgtttgggaa gaaaagaagg aaactaagac gtgcgagggg aagaaaaagg 3600 aaaacctaat taaaaaatat gtatcctcta taattagtta tgacagccat ttgtaatgaa 3660 tttgtcgcaa agacgtaata aaattaactg gtagcacggt ca 3702 <210> 167 <211> 1374 <212> DNA <213> HUMAN <400> 167 attgcggcgg cgccagagct gctggagcgc tcggggtccc cgggcggcgg cggcggcgca 60 gaggaggagg caggcggcgg ccccggtggc tcccccccgg acggtgcgcg gcccggcccg 120 tctcgcgaac tcgcggtggt cgcgcggccc cgcgctgctc cgaccccggg cccctccgcc 180 gccgccatgg ctcggccgct agtgcccagc tcgcagaagg cgctgctgct ggagctcaag 240 gggctgcagg aagagccggt cgagggattc cgcgtgacac tggtggacga gggcgatcta 300 tacaactggg aggtggccat tttcgggccc cccaacacct actacgaggg cggctacttc 360 aaggcgcgcc tcaagttccc catcgactac ccatactctc caccagcctt tcggttcctg 420 accaagatgt ggcaccctaa catctacgag acgggggacg tgtgtatctc catcctccac 480 ccgccggtgg acgaccccca gagcggggag ctgccctcag agaggtggaa ccccacgcag 540 aacgtcagga ccattctcct gagtgtgatc tccctcctga acgagcccaa caccttctcg 600 cccgcaaacg tggacgcctc cgtgatgtac aggaagtgga aagagagcaa ggggaaggat 660 cgggagtaca cagacatcat ccggaagcag gtcctgggga ccaaggtgga cgcggagcgt 720 gacggcgtga aggtgcccac cacgctggcc gagtactgcg tgaagaccaa ggcgccggcg 780 cccgacgagg gctcagacct cttctacgac gactactacg aggacggcga ggtggaggag 840 gaggccgaca gctgcttcgg ggacgatgag gatgactctg gcacggagga gtcctgacac 900 caccagaata aacttgccga gtttacctca ctagggccgg acccgtggct ccttagacga 960 cagactacct cacggaggtt ttgtgctggt ccccgtctcc tctggttgtt tcgttttggc 1020 tttttctccc tccccatgtc tgttctgggt tttcacgtgc ttcagagaag aggggctgcc 1080 ccaccgccac tcacgtcact cggggctcgg tggacgggcc cagggtggga gcggccggcc 1140 cacctgtccc ctcgggaggg gagctgagcc cgacttctac cggggtcccc cagcttccgg 1200 actggccgca ccccggagga gccacggggg cgctgctggg aacgtgggcg gggggccgtt 1260 tcctgacact accagcctgg gaggcccagg tgtagcggtc cgaggggccc ggtcctgcct 1320 gtcagctcca ggtcctggag ccacgtccag cactgagtgg acggattcac caat 1374 <210> 168 <211> 357 <212> DNA <213> HUMAN <400> 168 atggacgtgt tcctcatgat ccggcgccac aagaccacca tcttcacgga cgccaaggag 60 tccagcacgg tgttcgaact gaagcgcatc gtcgagggca tcctcaagcg gcctcctgac 120 gagcagcggc tgtacaagga tgaccaactc ttggatgatg gcaagacact gggcgagtgt 180 ggcttcacca gtcaaacagc acggccacag gccccagcca cagtggggct ggccttccgg 240 gcagatgaca cctttgaggc cctgtgcatc gagccgtttt ccagcccgcc agagctgccc 300 gatgtgatga agccccagga ctcgggaagc agtgccaatg aacaagccgt gcagtga 357 <210> 169 <211> 1309 <212> DNA <213> HUMAN <400> 169 gccagggttg cctgcgggag ccaggcgtcc gctctccaca cctttcacag ccccagccct 60 cagagcaacc tcagcccagc ccagcccagc tccagctcca gctccagccc gggccccatc 120 atggccaagg actttcaaga tatccagcag ctgagctcgg aggaaaatga ccatcctttc 180 catcaaggtg aggggccagg cactcgcagg ctgaatccca ggagaggaaa tccatttttg 240 aaagggccac ctcctgccca gcccctggca cagcgtctct gctccatggt ctgcttcagt 300 ctgcttgccc tgagcttcaa catcctgctg ctggtggtca tctgtgtgac tgggtcccaa 360 agtgagggtc acagaggtgc acagctgcaa gccgagctgc ggagcctgaa ggaagctttc 420 agcaacttct cctcgagcac cctgacggag gtccaggcaa tcagcaccca cggaggcagc 480 gtgggtgaca agatcacatc cctaggagcc aagctggaga aacagcagca ggacctgaaa 540 gcagatcacg atgccctgct cttccatctg aagcacttcc ccgtggacct gcgcttcgtg 600 gcctgccaga tggagctcct ccacagcaac ggctcccaaa ggacctgctg ccccgtcaac 660 tgggtggagc accaaggcag ctgctactgg ttctctcact ccgggaaggc ctgggctgag 720 gcggagaagt actgccagct ggagaacgca cacctggtgg tcatcaactc ctgggaggag 780 cagaaattca ttgtacaaca cacgaacccc ttcaatacct ggataggtct cacggacagt 840 gatggctctt ggaaatgggt ggatggcaca gactataggc acaactacaa gaactgggct 900 gtcactcagc cagataattg gcacgggcac gagctgggtg gaagtgaaga ctgtgttgaa 960 gtccagccgg atggccgctg gaacgatgac ttctgcctgc aggtgtaccg ctgggtgtgt 1020 gagaaaaggc ggaatgccac cggcgaggtg gcctgacccc agcacacctc tggctaaccc 1080 ataccccaca cctgcccagc tctggcttct ctgttgagga ttttgaggaa aggaagaaac 1140 actgagacag gggtatgggg aagagctgag caaagagaga aaggaggtag tttaagagtc 1200 cctgaccctg gaggactgag atcccacctc cttctgtaat tcattgtaat tattataatc 1260 gtcagcctct tcaatggcgt aggaaagaag aaacaaatgc ttgaatctc 1309 <210> 170 <211> 6030 <212> DNA <213> HUMAN <400> 170 gttggccccc gttacttttc ctctgggaaa tatggcgcac gctgggagaa cagggtacga 60 taaccgggag atagtgatga agtacatcca ttataagctg tcgcagaggg gctacgagtg 120 ggatgcggga gatgtgggcg ccgcgccccc gggggccgcc cccgcgccgg gcatcttctc 180 ctcgcagccc gggcacacgc cccatacagc cgcatcccgg gacccggtcg ccaggacctc 240 gccgctgcag accccggctg cccccggcgc cgccgcgggg cctgcgctca gcccggtgcc 300 acctgtggtc cacctgaccc tccgccaggc cggcgacgac ttctcccgcc gctaccgccg 360 cgacttcgcc gagatgtcca ggcagctgca cctgacgccc ttcaccgcgc ggggacgctt 420 tgccacggtg gtggaggagc tcttcaggga cggggtgaac tgggggagga ttgtggcctt 480 ctttgagttc ggtggggtca tgtgtgtgga gagcgtcaac cgggagatgt cgcccctggt 540 ggacaacatc gccctgtgga tgactgagta cctgaaccgg cacctgcaca cctggatcca 600 ggataacgga ggctgggatg cctttgtgga actgtacggc cccagcatgc ggcctctgtt 660 tgatttctcc tggctgtctc tgaagactct gctcagtttg gccctggtgg gagcttgcat 720 caccctgggt gcctatctgg gccacaagtg aagtcaacat gcctgcccca aacaaatatg 780 caaaaggttc actaaagcag tagaaataat atgcattgtc agtgatgttc catgaaacaa 840 agctgcaggc tgtttaagaa aaaataacac acatataaac atcacacaca cagacagaca 900 cacacacaca caacaattaa cagtcttcag gcaaaacgtc gaatcagcta tttactgcca 960 aagggaaata tcatttattt tttacattat taagaaaaaa agatttattt atttaagaca 1020 gtcccatcaa aactcctgtc tttggaaatc cgaccactaa ttgccaagca ccgcttcgtg 1080 tggctccacc tggatgttct gtgcctgtaa acatagattc gctttccatg ttgttggccg 1140 gatcaccatc tgaagagcag acggatggaa aaaggacctg atcattgggg aagctggctt 1200 tctggctgct ggaggctggg gagaaggtgt tcattcactt gcatttcttt gccctggggg 1260 ctgtgatatt aacagaggga gggttcctgt ggggggaagt ccatgcctcc ctggcctgaa 1320 gaagagactc tttgcatatg actcacatga tgcatacctg gtgggaggaa aagagttggg 1380 aacttcagat ggacctagta cccactgaga tttccacgcc gaaggacagc gatgggaaaa 1440 atgcccttaa atcataggaa agtatttttt taagctacca attgtgccga gaaaagcatt 1500 ttagcaattt atacaatatc atccagtacc ttaagccctg attgtgtata ttcatatatt 1560 ttggatacgc accccccaac tcccaatact ggctctgtct gagtaagaaa cagaatcctc 1620 tggaacttga ggaagtgaac atttcggtga cttccgcatc aggaaggcta gagttaccca 1680 gagcatcagg ccgccacaag tgcctgcttt taggagaccg aagtccgcag aacctgcctg 1740 tgtcccagct tggaggcctg gtcctggaac tgagccgggg ccctcactgg cctcctccag 1800 ggatgatcaa cagggcagtg tggtctccga atgtctggaa gctgatggag ctcagaattc 1860 cactgtcaag aaagagcagt agaggggtgt ggctgggcct gtcaccctgg ggccctccag 1920 gtaggcccgt tttcacgtgg agcatgggag ccacgaccct tcttaagaca tgtatcactg 1980 tagagggaag gaacagaggc cctgggccct tcctatcaga aggacatggt gaaggctggg 2040 aacgtgagga gaggcaatgg ccacggccca ttttggctgt agcacatggc acgttggctg 2100 tgtggccttg gcccacctgt gagtttaaag caaggcttta aatgactttg gagagggtca 2160 caaatcctaa aagaagcatt gaagtgaggt gtcatggatt aattgacccc tgtctatgga 2220 attacatgta aaacattatc ttgtcactgt agtttggttt tatttgaaaa cctgacaaaa 2280 aaaaagttcc aggtgtggaa tatgggggtt atctgtacat cctggggcat taaaaaaaaa 2340 atcaatggtg gggaactata aagaagtaac aaaagaagtg acatcttcag caaataaact 2400 aggaaatttt tttttcttcc agtttagaat cagccttgaa acattgatgg aataactctg 2460 tggcattatt gcattatata ccatttatct gtattaactt tggaatgtac tctgttcaat 2520 gtttaatgct gtggttgata tttcgaaagc tgctttaaaa aaatacatgc atctcagcgt 2580 ttttttgttt ttaattgtat ttagttatgg cctatacact atttgtgagc aaaggtgatc 2640 gttttctgtt tgagattttt atctcttgat tcttcaaaag cattctgaga aggtgagata 2700 agccctgagt ctcagctacc taagaaaaac ctggatgtca ctggccactg aggagctttg 2760 tttcaaccaa gtcatgtgca tttccacgtc aacagaattg tttattgtga cagttatatc 2820 tgttgtccct ttgaccttgt ttcttgaagg tttcctcgtc cctgggcaat tccgcattta 2880 attcatggta ttcaggatta catgcatgtt tggttaaacc catgagattc attcagttaa 2940 aaatccagat ggcaaatgac cagcagattc aaatctatgg tggtttgacc tttagagagt 3000 tgctttacgt ggcctgtttc aacacagacc cacccagagc cctcctgccc tccttccgcg 3060 ggggctttct catggctgtc cttcagggtc ttcctgaaat gcagtggtgc ttacgctcca 3120 ccaagaaagc aggaaacctg tggtatgaag ccagacctcc ccggcgggcc tcagggaaca 3180 gaatgatcag acctttgaat gattctaatt tttaagcaaa atattatttt atgaaaggtt 3240 tacattgtca aagtgatgaa tatggaatat ccaatcctgt gctgctatcc tgccaaaatc 3300 attttaatgg agtcagtttg cagtatgctc cacgtggtaa gatcctccaa gctgctttag 3360 aagtaacaat gaagaacgtg gacgctttta atataaagcc tgttttgtct tctgttgttg 3420 ttcaaacggg attcacagag tatttgaaaa atgtatatat attaagaggt cacgggggct 3480 aattgctggc tggctgcctt ttgctgtggg gttttgttac ctggttttaa taacagtaaa 3540 tgtgcccagc ctcttggccc cagaactgta cagtattgtg gctgcacttg ctctaagagt 3600 agttgatgtt gcattttcct tattgttaaa aacatgttag aagcaatgaa tgtatataaa 3660 agcctcaact agtcattttt ttctcctctt cttttttttc attatatcta attattttgc 3720 agttgggcaa cagagaacca tccctatttt gtattgaaga gggattcaca tctgcatctt 3780 aactgctctt tatgaatgaa aaaacagtcc tctgtatgta ctcctcttta cactggccag 3840 ggtcagagtt aaatagagta tatgcacttt ccaaattggg gacaagggct ctaaaaaaag 3900 ccccaaaagg agaagaacat ctgagaacct cctcggccct cccagtccct cgctgcacaa 3960 atactccgca agagaggcca gaatgacagc tgacagggtc tatggccatc gggtcgtctc 4020 cgaagatttg gcaggggcag aaaactctgg caggcttaag atttggaata aagtcacaga 4080 atcaaggaag cacctcaatt tagttcaaac aagacgccaa cattctctcc acagctcact 4140 tacctctctg tgttcagatg tggccttcca tttatatgtg atctttgttt tattagtaaa 4200 tgcttatcat ctaaagatgt agctctggcc cagtgggaaa aattaggaag tgattataaa 4260 tcgagaggag ttataataat caagattaaa tgtaaataat cagggcaatc ccaacacatg 4320 tctagctttc acctccagga tctattgagt gaacagaatt gcaaatagtc tctatttgta 4380 attgaactta tcctaaaaca aatagtttat aaatgtgaac ttaaactcta attaattcca 4440 actgtacttt taaggcagtg gctgttttta gactttctta tcacttatag ttagtaatgt 4500 acacctactc tatcagagaa aaacaggaaa ggctcgaaat acaagccatt ctaaggaaat 4560 tagggagtca gttgaaattc tattctgatc ttattctgtg gtgtcttttg cagcccagac 4620 aaatgtggtt acacactttt taagaaatac aattctacat tgtcaagctt atgaaggttc 4680 caatcagatc tttattgtta ttcaatttgg atctttcagg gatttttttt ttaaattatt 4740 atgggacaaa ggacatttgt tggaggggtg ggagggagga acaattttta aatataaaac 4800 attcccaagt ttggatcagg gagttggaag ttttcagaat aaccagaact aagggtatga 4860 aggacctgta ttggggtcga tgtgatgcct ctgcgaagaa ccttgtgtga caaatgagaa 4920 acattttgaa gtttgtggta cgacctttag attccagaga catcagcatg gctcaaagtg 4980 cagctccgtt tggcagtgca atggtataaa tttcaagctg gatatgtcta atgggtattt 5040 aaacaataaa tgtgcagttt taactaacag gatatttaat gacaaccttc tggttggtag 5100 ggacatctgt ttctaaatgt ttattatgta caatacagaa aaaaatttta taaaattaag 5160 caatgtgaaa ctgaattgga gagtgataat acaagtcctt tagtcttacc cagtgaatca 5220 ttctgttcca tgtctttgga caaccatgac cttggacaat catgaaatat gcatctcact 5280 ggatgcaaag aaaatcagat ggagcatgaa tggtactgta ccggttcatc tggactgccc 5340 cagaaaaata acttcaagca aacatcctat caacaacaag gttgttctgc ataccaagct 5400 gagcacagaa gatgggaaca ctggtggagg atggaaaggc tcgctcaatc aagaaaattc 5460 tgagactatt aataaataag actgtagtgt agatactgag taaatccatg cacctaaacc 5520 ttttggaaaa tctgccgtgg gccctccaga tagctcattt cattaagttt ttccctccaa 5580 ggtagaattt gcaagagtga cagtggattg catttctttt ggggaagctt tcttttggtg 5640 gttttgttta ttataccttc ttaagttttc aaccaaggtt tgcttttgtt ttgagttact 5700 ggggttattt ttgttttaaa taaaaataag tgtacaataa gtgtttttgt attgaaagct 5760 tttgttatca agattttcat acttttacct tccatggctc tttttaagat tgatactttt 5820 aagaggtggc tgatattctg caacactgta cacataaaaa atacggtaag gatactttac 5880 atggttaagg taaagtaagt ctccagttgg ccaccattag ctataatggc actttgtttg 5940 tgttgttgga aaaagtcaca ttgccattaa actttccttg tctgtctagt taatattgtg 6000 aagaaaaata aagtacagtg tgagatactg 6030 <210> 171 <211> 4740 <212> DNA <213> HUMAN <400> 171 ttccggtttt tctcagggga cgttgaaatt atttttgtaa cgggagtcgg gagaggacgg 60 ggcgtgcccc gcgtgcgcgc gcgtcgtcct ccccggcgct cctccacagc tcgctggctc 120 ccgccgcgga aaggcgtcat gccgcccaaa accccccgaa aaacggccgc caccgccgcc 180 gctgccgccg cggaaccccc ggcaccgccg ccgccgcccc ctcctgagga ggacccagag 240 caggacagcg gcccggagga cctgcctctc gtcaggcttg agtttgaaga aacagaagaa 300 cctgatttta ctgcattatg tcagaaatta aagataccag atcatgtcag agagagagct 360 tggttaactt gggagaaagt ttcatctgtg gatggagtat tgggaggtta tattcaaaag 420 aaaaaggaac tgtggggaat ctgtatcttt attgcacgag ttgacctaga tgagatgtcg 480 ttcactttac tgagctacag aaaaacatac gaaatcagtg tccataaatt ctttaactta 540 ctaaaagaaa ttgataccag taccaaagtt gataatgcta tgtcaagact gttgaagaag 600 tatgatgtat tgtttgcact cttcagcaaa ttggaaagga catgtgaact tatatatttg 660 acacaaccca gcagttcgat atctactgaa ataaattctg cattggtgct aaaagtttct 720 tggatcacat ttttattagc taaaggggaa gtattacaaa tggaagatga tctggtgatt 780 tcatttcagt taatgctatg tgtccttgac tattttatta aactctcacc tcccatgttg 840 ctcaaagaac catataaaac agctgttata cccattaatg gttcacctcg aacacccagg 900 cgaggtcaga acaggagtgc acggatagca aaacaactag aaaatgatac aagaattatt 960 gaagttctct gtaaagaaca tgaatgtaat atagatgagg tgaaaaatgt ttatttcaaa 1020 aattttatac cttttatgaa ttctcttgga cttgtaacat ctaatggact tccagaggtt 1080 gaaaatcttt ctaaacgata cgaagaaatt tatcttaaaa ataaagatct agatcgaaga 1140 ttatttttgg atcatgataa aactcttcag actgattcta tagacagttt tgaaacacag 1200 agaacaccac gaaaaagtaa ccttgatgaa gaggtgaata taattcctcc acacactcca 1260 gttaggactg ttatgaacac tatccaacaa ttaatgatga ttttaaattc tgcaagtgat 1320 caaccttcag aaaatctgat ttcctatttt aacaactgca cagtgaatcc aaaagaaagt 1380 atactgaaaa gagtgaagga tataggatac atctttaaag agaaatttgc taaagctgtg 1440 ggacagggtt gtgtcgaaat tggatcacag cgatacaaac ttggagttcg cttgtattac 1500 cgagtaatgg aatccatgct taaatcagaa gaagaacgat tatccattca aaattttagc 1560 aaacttctga atgacaacat ttttcatatg tctttattgg cgtgcgctct tgaggttgta 1620 atggccacat atagcagaag tacatctcag aatcttgatt ctggaacaga tttgtctttc 1680 ccatggattc tgaatgtgct taatttaaaa gcctttgatt tttacaaagt gatcgaaagt 1740 tttatcaaag cagaaggcaa cttgacaaga gaaatgataa aacatttaga acgatgtgaa 1800 catcgaatca tggaatccct tgcatggctc tcagattcac ctttatttga tcttattaaa 1860 caatcaaagg accgagaagg accaactgat caccttgaat ctgcttgtcc tcttaatctt 1920 cctctccaga ataatcacac tgcagcagat atgtatcttt ctcctgtaag atctccaaag 1980 aaaaaaggtt caactacgcg tgtaaattct actgcaaatg cagagacaca agcaacctca 2040 gccttccaga cccagaagcc attgaaatct acctctcttt cactgtttta taaaaaagtg 2100 tatcggctag cctatctccg gctaaataca ctttgtgaac gccttctgtc tgagcaccca 2160 gaattagaac atatcatctg gacccttttc cagcacaccc tgcagaatga gtatgaactc 2220 atgagagaca ggcatttgga ccaaattatg atgtgttcca tgtatggcat atgcaaagtg 2280 aagaatatag accttaaatt caaaatcatt gtaacagcat acaaggatct tcctcatgct 2340 gttcaggaga cattcaaacg tgttttgatc aaagaagagg agtatgattc tattatagta 2400 ttctataact cggtcttcat gcagagactg aaaacaaata ttttgcagta tgcttccacc 2460 aggcccccta ccttgtcacc aatacctcac attcctcgaa gcccttacaa gtttcctagt 2520 tcacccttac ggattcctgg agggaacatc tatatttcac ccctgaagag tccatataaa 2580 atttcagaag gtctgccaac accaacaaaa atgactccaa gatcaagaat cttagtatca 2640 attggtgaat cattcgggac ttctgagaag ttccagaaaa taaatcagat ggtatgtaac 2700 agcgaccgtg tgctcaaaag aagtgctgaa ggaagcaacc ctcctaaacc actgaaaaaa 2760 ctacgctttg atattgaagg atcagatgaa gcagatggaa gtaaacatct cccaggagag 2820 tccaaatttc agcagaaact ggcagaaatg acttctactc gaacacgaat gcaaaagcag 2880 aaaatgaatg atagcatgga tacctcaaac aaggaagaga aatgaggatc tcaggacctt 2940 ggtggacact gtgtacacct ctggattcat tgtctctcac agatgtgact gtataacttt 3000 cccaggttct gtttatggcc acatttaata tcttcagctc tttttgtgga tataaaatgt 3060 gcagatgcaa ttgtttgggt gagtcctaag ccacttgaaa tgttagtcat tgttatttat 3120 acaagattga aaatcttgtg taaatcctgc catttaaaaa gttgtagcag attgtttcct 3180 cttccaaagt aaaattgctg tgctttatgg atagtaagaa tggccctaga gtgggagtcc 3240 tgataaccca ggcctgtctg actactttgc cttcttttgt agcatatagg tgatgtttgc 3300 tcttgttttt attaatttat atgtatattt ttttaattta acatgaacac ccttagaaaa 3360 tgtgtcctat ctatcttcca aatgcaattt gattgactgc ccattcacca aaattatcct 3420 gaactcttct gcaaaaatgg atattattag aaattagaaa aaaattacta attttacaca 3480 ttagatttta ttttactatt ggaatctgat atactgtgtg cttgttttat aaaattttgc 3540 ttttaattaa ataaaagctg gaagcaaagt ataaccatat gatactatca tactactgaa 3600 acagatttca tacctcagaa tgtaaaagaa cttactgatt attttcttca tccaacttat 3660 gtttttaaat gaggattatt gatagtactc ttggttttta taccattcag atcactgaat 3720 ttataaagta cccatctagt acttgaaaaa gtaaagtgtt ctgccagatc ttaggtatag 3780 aggaccctaa cacagtatat cccaagtgca ctttctaatg tttctgggtc ctgaagaatt 3840 aagatacaaa ttaattttac tccataaaca gactgttaat tataggagcc ttaatttttt 3900 tttcatagag atttgtctaa ttgcatctca aaattattct gccctcctta atttgggaag 3960 gtttgtgttt tctctggaat ggtacatgtc ttccatgtat cttttgaact ggcaattgtc 4020 tatttatctt ttattttttt aagtcagtat ggtctaacac tggcatgttc aaagccacat 4080 tatttctagt ccaaaattac aagtaatcaa gggtcattat gggttaggca ttaatgtttc 4140 tatctgattt tgtgcaaaag cttcaaatta aaacagctgc attagaaaaa gaggcgcttc 4200 tcccctcccc tacacctaaa ggtgtattta aactatcttg tgtgattaac ttatttagag 4260 atgctgtaac ttaaaatagg ggatatttaa ggtagcttca gctagctttt aggaaaatca 4320 ctttgtctaa ctcagaatta tttttaaaaa gaaatctggt cttgttagaa aacaaaattt 4380 tattttgtgc tcatttaagt ttcaaactta ctattttgac agttattttg ataacaatga 4440 cactagaaaa cttgactcca tttcatcatt gtttctgcat gaatatcata caaatcagtt 4500 agtttttagg tcaagggctt actatttctg ggtcttttgc tactaagttc acattagaat 4560 tagtgccaga attttaggaa cttcagagat cgtgtattga gatttcttaa ataatgcttc 4620 agatattatt gctttattgc ttttttgtat tggttaaaac tgtacattta aaattgctat 4680 gttactattt tctacaatta atagtttgtc tattttaaaa taaattagtt gttaagagtc 4740 <210> 172 <211> 7824 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(7824) <223> N=any base <400> 172 aaagtatgtg catgtataaa tctgtgtgtc ttccactttg tcccacatat actaaattta 60 aacattcttc taacgtggga aaatccagta ttttaatgtg gacatcaact gcacaacgat 120 tgtcaggaaa acaatgcata tttgcactgg tgatacattt gcaaaatctg tcatagtttg 180 ctactccttg cccttccatg aaccagagaa ttatctcagt ttattagtcc cctcccctaa 240 gaagcttcca ccaatactct tttccccttt cctttaactt gattgtgaaa tcaggtattc 300 aacagagaaa tttctcagcc tcctacttct gcttttgaaa gccataaaaa cagcgaggga 360 gaaactggca gataccaaac ctcttcgagg cacaaggcac aacaggctgc tctgggattc 420 tcttcagcca atcttcattg ctcaagtatg actttaatct tccttacaac taggtgctaa 480 gggagtctct ctgtctctct gcctctttgt gtgtatgcat attctctctc tctctctctt 540 tctttctctg tctctccctc tccttccctc tctgcctccc tctctcagct ttttgcaaaa 600 agccaggtgt aatataatgc ttatgactcg ggaaatattc tgggaatgga tactgcttat 660 ctaacagctg acaccctaaa ggttagtgtc aaagcctctg ctccagctct cctagcctaa 720 tacattgcta gttggggttt ggtttagcaa atgcttttct ctagacccaa aggacttctc 780 tttcacacat tcattcattt actcagagat catttctttg catgactgcc atgcactgga 840 tgctgagaga aatcacacat gaacgtagcc gtcatgggga agtcactcat tttctccttt 900 ttacacaggt gtctgaagca gccatggcag aagtacctga gctcgccagt gaaatgatgg 960 cttattacag gtcagtggag acgctgagac cagtaacatg agcaggtctc ctctttcaag 1020 agtagagtgt tatctgtgct tggagaccag atttttcccc taaattgcct ctttcagtgg 1080 caaacagggt gccaagtaaa tctgatttaa agactacttt cccattacaa gtccctccag 1140 ccttgggacc tggaggctat ccagatgtgt tgttgcaagg gcttcctgca gaggcaaatg 1200 gggagaaaag actccaagcc cacaatacaa ggaatccctt tgcaaagtgt ggcttggagg 1260 gagagggaga gctcagattt tagctgactc tgctgggcta gaggttaggc ctcaagatcc 1320 aacagggagc ncccagggtg cccacctgcc aggcctagaa tctgccttct ggactgttct 1380 gcgcatatca ctgtgaaact tgccaggtgt ttcaggcagc tttgagaggc aggctgtttg 1440 cagtttctta tgaacagtca agtcttgtac acagggaagg aaaaataaac ctgtttagaa 1500 gacataattg agacatgtcc ctgtttttat tacagtggca atgaggatga cttgttcttt 1560 gaagctgatg gccctaaaca gatgaaggta agactatggg tttaactccc aacccaagga 1620 agggctctaa cacagggaaa gctcaaagaa gggagttctg ggccactttg atgccatggt 1680 attttgtttt agaaagactt taacctcttc cagtgagaca caggctgcac cacttgctga 1740 cctggccact tggtcatcat atcaccacag tcactcacta acgttggtgg tggtggccac 1800 acttggtggt gacaggggag gagtagtgat aatgtttccc atttcatagt aggaagacaa 1860 ccaagtcttc aacataaatt tgattatcct tttaagagat ggattcagcc tatgccaatc 1920 acttgagtta aactctgaaa ccaagagatg atcttgagaa ctaacatatg tctacccctt 1980 ttgagtagaa tagttttttg ctacctgggg tgaagcttat aacaacaaga catagatgat 2040 ataaacaaaa agatcaattg agacttgaaa gaaaaccatt cacttgctgt ttgaccttga 2100 caagtcattt tacccgcttt ggacctcatc tgaaaaataa agggctgagc tggatgatct 2160 ctgagattcc agcatcctgc aacctccagt tctgaaatat tttcagttgt agctaagggc 2220 atttgggcag caaatggtca tttttcagac tcatccttac aaagagccat gttatattcc 2280 tgctgtccct tctgttttat atgatggctc agtagccttc ctagtggccc agccatcagc 2340 ctagctaggt cagttgtgca ggttggaggc agccactttt ctctggcttt attttattcc 2400 agtttgtgat agcctcccct agcctcataa tccagtcctc aatcttgtta aaaacatatt 2460 tctttagaag ttttaagact ggcataactt gttggctgca gctgtgggag gagcccattg 2520 gcttgtctgc ctggcctttg cccccattgc ctcttccagc agcttggcgc tgctccaggc 2580 aggaaattct ctcctgctca actttctttt gtgcacttac aggtctcttt aactgtcttt 2640 caagcctttg aaccattatc actgccttaa ggcaacctca gtgaagcctt aatacggagc 2700 ttctctgaat aagaggaaag tggtaacatt tcacaaaaag tactctcaca ggatttgcag 2760 aatgcctatg agacagtgtt atgaaaaagg aaaaaaaaga acagtgtaga aaaattgaat 2820 acttgctgag tgagcatagg tgaatggaaa atgttatggt catctgcatg aaaaagcaaa 2880 tcatagtgtg acagcattag ggatacaaaa agatatagag aaggtataca tgtatggtgt 2940 aggtggggca tgtacaaaaa agatgaacaa agtagaaatg ggatttattc taaagaatag 3000 cctgtaaggt gtcagaaagc ccacattcta gtcttgagtc tgtttctaac ctgctgtgtg 3060 cccttgagta cacacttaac ctcttgagct tcagagaggg ataatctttt tattttattt 3120 tattttattt tgttttgttt tgttttgttt tgttttatga gacagagtct cactctgttg 3180 cccaggctgg agtgcagtgg tacaatcttg gcttactgca tcctccacct cctgagttca 3240 agcgattctc cttcctcagt ctcctgaata gctaggatta caggtgcacc ccaccacacc 3300 cagctaattt ttgtattttt agtagagaag gggtttcgcc atgttggcca ggctggtttt 3360 gaagtcctga cctaaatgat tcatccacct cggcttccca aagtgctggg attacaggca 3420 tgagccacca cgcctggccc agagagggat gatctttaga agctcgggat tctttcaagc 3480 cctttcctcc tctctgagct ttctactctc tgatgtcaaa gcatggttcc tggcaggacc 3540 acctcaccag gctccctccc tcgctctctc cgcagtgctc cttccaggac ctggacctct 3600 gccctctgga tggcggcatc cagctacgaa tctccgacca ccactacagc aagggcttca 3660 ggcaggccgc gtcagttgtt gtggccatgg acaagctgag gaagatgctg gttccctgcc 3720 cacagacctt ccaggagaat gacctgagca ccttctttcc cttcatcttt gaagaaggta 3780 gttagccaag agcaggcagt agatctccac ttgtgtcctc ttggaagtca tcaagcccca 3840 gccaactcaa ttcccccaga gccaaagccc tttaaaggta gaaggcccag cggggagaca 3900 aaacaaagaa ggctggaaac caaagcaatc atctctttag tggaaactat tcttaaagaa 3960 gatcttgatg gctactgaca tttgcaactc cctcactctt tctcaggggc ctttcactta 4020 cattgtcacc agaggttcgt aacctccctg tgggctagtg ttatgaccat caccatttta 4080 cctaagtagc tctgttgctc ggccacagtg agcagtaata gacctgaagc tggaacccat 4140 gtctaatagt gtcaggtcca tgttcttagc caccccactc ccagcttcat ccctactggt 4200 gttgtcatca gactttgacc gtatatgctc agtgtcctcc aagaaatcaa attttgccgc 4260 ctcgcctcac gaggcctgcc cttctgattt tatacctaaa caacatgtgc tccacatttc 4320 agaacctatc ttcttcgaca catgggataa cgaggcttat gtgcacgatg cacctgtacg 4380 atcactgaac tgcacgctcc gggactcaca gcaaaaaagc ttggtgatgt ctggtccata 4440 tgaactgaaa gctctccacc tccagggaca ggatatggag caacaaggta aatggaaaca 4500 tcctggtttc cctgcctggc ctcctggcag cttgctaatt ctccatgttt taaacaaagt 4560 agaaagttaa tttaaggcaa atgatcaaca caagtgaaaa aaaatattaa aaaggaatat 4620 acaaactttg gtcctagaaa tggcacattt gattgcactg gccagtgcat ttgttaacag 4680 gagtgtgacc ctgagaaatt agacggtcaa gcactcccag gaccatgtcc acccaagtct 4740 cttgggcata gtgcaatgtc aattcttcca caatatcccc tcatttgatg gacatggcct 4800 aactgcctgt gggttctctc ttcctgttgt tgaggctgaa acaagagtgc tggagcgata 4860 atgtgtccat cccctcccca gtcttccccc cttgccccaa cagtccgtcc cacccaatgc 4920 aggtggttct tgtagggaaa ttttaccgcc cagcaggaac ttatatctct ccgctgtaac 4980 gggcaaaagt ttcaagtgcg gtgaacccat cattagctgt ggtgatctgc ctggcatcgt 5040 gccacagtag ccaaagcctc tgcacaggag tgtgggcaac taaggctgct gactttgaag 5100 gacagcctca ctcaggggga agctatttgc tctcagccag gccaagaaaa tcctgtttct 5160 ttggaatcgg gtagtaagag tgatcccagg gcctccaatt gacactgctg tgactgagga 5220 agatcaaaat gagtgtctct ctttggagcc actttcccag ctcagcctct cctctcccag 5280 tttcttccca tgggctactc tctgttcctg aaacagttct ggtgcctgat ttctggcaga 5340 agtacagctt cacctctttc ctttccttcc acattgatca agttgttccg ctcctgtgga 5400 tgggcacatt gccagccagt gacacaatgg cttccttcct tccttccttc agcatttaaa 5460 atgtagaccc tctttcattc tccgttccta ctgctatgag gctctgagaa acctcaggcc 5520 tttgagggga aaccctaaat caacaaaatg accctgctat tgtctgtgag aagtcaagtt 5580 atcctgtgtc ttaggccaag gaacctcact gtgggttccc acagaggcta ccaaattaca 5640 tgtatcctac tcatggggcc taggggttgg ggtgaccctg cactgctgtg tccctaacca 5700 caagaccccc ttctttcttc agtggtgttc tccatgtcct ttgtacaagg agaagaaagt 5760 aatgacaaaa tacctgtggc cttgggcctc aaggaaaaga atctgtacct gtcctgcgtg 5820 ttgaaagatg ataagcccac tctacagctg gaggtaagtg aatgctatgg aatgaagccc 5880 ttctcagcct cctgctacca cttattccca gacaaccacc ttctccccgc ccccatccct 5940 aggaaaagct gggaacaggt ctatttgaca attttgcatt aatgtaaata aatttaacat 6000 aatttttaac tgcgtgcaac cttcaatcct gctgcagaaa attaaatcat tttgccgatg 6060 ttattatgtc ctaccatagt tacaacccca acagattata tattgttagg gctgctctca 6120 tttgatagac accttgggaa atagatgact taaagggtcc cattatcacg tccactccac 6180 tcccaaaatc accaccacta tcacctccag ctttctcagc aaaagcttca tttccaagtt 6240 gatgtcattc taggaccata aggaaaaata caataaaaag cccctggaaa ctaggtactt 6300 caagaagctc tagcttaatt ttcacccccc aaaaaaaaaa aattctcacc tacattatgc 6360 tcctcagcat ttggcactaa gttttagaaa agaagagggc tcttttaaat aaattcacac 6420 agaaagttgg gcccagttac aactcaggag tctggctcct gatcatgtga cctgctcgtc 6480 agtttccttt ctggccaacc caaagaacat ctttcccata gcatctttgt cccttgcccc 6540 acaaaaattc ttctttctct ttcgtgcaga gtgtagatcc caaaaattac ccaaagaaga 6600 agatggaaaa gcgatttgtc ttcaacaaga tagaaatcaa taacaagctg gaatttgagt 6660 ctgcccagtt ccccaactgg tacatcagca cctctcaagc agaaaacatg cccgtcttcc 6720 tgggagggac caaaggcggc caggatataa ctgacttcac catgcaattt gtgtcttcct 6780 aaagagagct gtacccagag agtcctgtgc tgaatgtgga ctcaatccct agggctggca 6840 gaaagggaac agaaaggttt ttgagtacgg ctatagcctg gactttcctg ttgtctacac 6900 caatgcccaa ctgcctgcct tagggtagtg ctaagaggat ctcctgtcca tcagccagga 6960 cagtcagctc tctcctttca gggccaatcc ccagcccttt tgttgagcca ggcctctctc 7020 acctctccta ctcacttaaa gcccgcctga cagaaaccac ggccacattt ggttctaaga 7080 aaccctctgt cattcgctcc cacattctga tgagcaaccg cttccctatt tatttattta 7140 tttgtttgtt tgttttattc attggtctaa tttattcaaa gggggcaaga agtagcagtg 7200 tctgtaaaag agcctagttt ttaatagcta tggaatcaat tcaatttgga ctggtgtgct 7260 ctctttaaat caagtccttt aattaagact gaaaatatat aagctcagat tatttaaatg 7320 ggaatattta taaatgagca aatatcatac tgttcaatgg ttctgaaata aacttcactg 7380 aagaaaaaaa aagggtcttt cctgatcatt gacttgtctt ggatttgaca ctgaacagta 7440 aagacaaaca gggctgtgag agttcttggg ggactaaagc ccacctcctc attgctgagt 7500 gctgcaaagt cacctagaaa tatcccttgg ccaccgaaga ctatcctcct cacccatccc 7560 ctttatttct gttgttcaac agaaggatat tcagtgcaca tctggaacag gatcagctga 7620 agcactgcag ggagtcagga ctggtagtaa cagctaccag tgatttatct atcaatgcac 7680 caaacatctg ttgagcaagc gctatgtacg aggagctggg agtacagaga tgagaacagt 7740 cacaagtccc tcctcagata ggagaggcag ctagttataa gcagaaacaa ggtaacatga 7800 caagtagagt aagataaaga acaa 7824 <210> 173 <211> 405 <212> DNA <213> HUMAN <400> 173 ggttcctggt cctcgcctcc tccgctgtct ccctggagtt cttgcaagtc ggccaggatg 60 tctcaggctg agtttgagaa agctgcagag gaggttaggc accttaagac caagccatcg 120 gatgaggaga tgctgttcat ctatggccac tacaaacaag caactgtggg cgacataaat 180 acagaacggc ccgggatgtt ggacttcacg ggcaaggcca agtgggatgc ctggaatgag 240 ctgaaaggga cttccaagga agatgccatg aaagcttaca tcaacaaagt agaagagcta 300 aagaaaaaat acgggatatg agagactgga tttggttact gtgccatgtg tttatcctaa 360 actgagacaa tgccttgttt ttttctaata ccgtggatgg tggaa 405 <210> 174 <211> 2428 <212> DNA <213> HUMAN <400> 174 cgaggcgcta gggggaacgc tggcctctga aactagctct gggaccgggg tctgcggccg 60 gcccctagct ggccccgtct cccatcccca gaagggtatt cactggggat tctgagcttt 120 ggctactcca gtttcccacg acacgatgtt ccctttctac agctgctgga ggactggact 180 gctactacta ctcctggctg tggcagtgag agaatcctgg cagacagaag aaaaaacttg 240 cgacttggta ggagaaaagg gtaaagagtc agagaaagag ttggctctag tgaagaggct 300 gaaaccactg tttaataaaa gctttgagag cactgtgggc cagggttcag acacatacat 360 ctacatcttc agggtgtgcc gggaagctgg caaccacact tctggggcag gcctggtgca 420 aatcaacaaa agtaatggga aggagacagt ggtagggaga ctcaacgaga ctcacatctt 480 caacggaagt aattggatca tgctgatcta taaagggggt gatgaatatg acaaccactg 540 tggcaaggag cagcgtcgtg cagtggtgat gatctcctgc aatcgacaca ccctagcgga 600 caattttaac cctgtgtctg aggagcgtgg caaagtccaa gattgtttct acctctttga 660 gatggatagc agcctggcct gttcaccaga gatctcccac ctcagtgtgg gttccatctt 720 acttgtcacg tttgcatcac tggttgctgt ttatgttgtt ggggggttcc tataccagcg 780 actggtagtg ggagccaaag gaatggagca gtttccccac ttagccttct ggcaggatct 840 tggcaacctg gtagcagatg gctgtgactt tgtctgccgt tctaaacctc gaaatgtgcc 900 tgcagcatat cgtggtgtgg gggatgacca gctgggggag gagtcagaag aaagggatga 960 ccatttatta ccaatgtaga ttgcacttta tatgtccagc ctcttcctca gtcccccaaa 1020 ccaaagctac acagccagat ttctcaagca gtctcaactc cagtccctca tctcaccctt 1080 actattgctc ttgctttcca gtttgctttt gatttgcatc ttctcactag taaaactgcc 1140 ttccctttgt tccttatttt ctgttttttc tctagagagg tacagttgta agtcagagtt 1200 aatataatag ggcctgtgaa aacagaggct tttgcattgt ctcttgacat cagaagttac 1260 aataggcata tgggcaaaat ggtgtagcag gctcactggc cgtttgtttt ttaaacacat 1320 tttcacaagt ttttgagaca ctggatttct ttaattaaaa aaaaaatgcc aagaaacatt 1380 atttatacag ggttgattgc tttcatgttg ttattctgta ccctatagta gcctccatga 1440 gaatctggta tttcttgctg cttggaacta ctttgcagtg attacttggt tgcagtccaa 1500 gtactctcgt ttagtctgag cctggagatg ttctagactt gcttctccca cctctgagat 1560 taggacagga aaaatgtgaa atttcccaat tacaggatta tacggtacca tcacatcatt 1620 tgtggaaatt ggggtgactg tatagctggg attgggctaa ggactgtggt cttatctgtc 1680 cacatacagc caaaatgcct atccagaaat ccagttcgtt ggaaaggaaa attggtactc 1740 ctgtgccaca ggggttccag aaaagggaag tcactttacc ttgcggtggt gggatcctga 1800 tgtctttcat ccatttgtag taaaagctgg taaagctttt cttactcctg gttccctacc 1860 agtatttcta aacatgtcgc actttctcca caggcatgtg gttttgacct ttttttcaat 1920 cttctagaaa gggaacggaa gcagaagtgg gacatcgagg gctctgctgt cctctgcgct 1980 gggtgtggaa tgctgctgca cctgtccctt ctgctggctc agggaagtgt cttcttgccc 2040 acatttctgt ggggaaaggt ttttaatcct ctgatgcttc catcttcctg tttaggccat 2100 gtgcccagaa acctggactg atctttcttt aatagtgaac ccctgggcca ctgaagagta 2160 acatggctcc actggacaca aaagagggat ggaatcaaca ggcagggggc cttttataag 2220 ccttaggaaa agaaaatgaa actatttcat ctttggactt ttcaatacta ttggagtgat 2280 ttttttcttt ctaaacaggg aaaataatgt tacaaaagca tcttttttgt tatttgtttg 2340 catccctccc ccacaccctg gtgttttaaa atgaagaaaa aaaaccatca ccttttgtac 2400 aaaaactctt aatgattaaa aaacaaac 2428 <210> 175 <211> 1639 <212> DNA <213> HUMAN <400> 175 acaaactttc agagacagca gagcacacaa gcttctagga caagagccag gaagaaacca 60 ccggaaggaa ccatctcact gtgtgtaaac atgacttcca agctggccgt ggctctcttg 120 gcagccttcc tgatttctgc agctctgtgt gaaggtgcag ttttgccaag gagtgctaaa 180 gaacttagat gtcagtgcat aaagacatac tccaaacctt tccaccccaa atttatcaaa 240 gaactgagag tgattgagag tggaccacac tgcgccaaca cagaaattat tgtaaagctt 300 tctgatggaa gagagctctg tctggacccc aaggaaaact gggtgcagag ggttgtggag 360 aagtttttga agagggctga gaattcataa aaaaattcat tctctgtggt atccaagaat 420 cagtgaagat gccagtgaaa cttcaagcaa atctacttca acacttcatg tattgtgtgg 480 gtctgttgta gggttgccag atgcaataca agattcctgg ttaaatttga atttcagtaa 540 acaatgaata gtttttcatt gtaccatgaa atatccagaa catacttata tgtaaagtat 600 tatttatttg aatctacaaa aaacaacaaa taatttttga atataaggat tttcctagat 660 attgcacggg agaatataca aatagcaaaa ttgggccaag ggccaagaga atatccgaac 720 tttaatttca ggaattgaat gggtttgcta gaatgtgata tttgaagcat cacataaaaa 780 tgatgggaca ataaattttg ccataaagtc aaatttagct ggaaatcctg gatttttttc 840 tgttaaatct ggcaacccta gtctgctagc caggatccac aagtccttgt tccactgtgc 900 cttggtttct cctttatttc taagtggaaa aagtattagc caccatctta cctcacagtg 960 atgttgtgag gacatgtgga agcactttaa gttttttcat cataacataa attattttca 1020 agtgtaactt attaacctat ttattattta tgtatttatt taagcatcaa atatttgtgc 1080 aagaatttgg aaaaatagaa gatgaatcat tgattgaata gttataaaga tgttatagta 1140 aatttatttt attttagata ttaaatgatg ttttattaga taaatttcaa tcagggtttt 1200 tagattaaac aaacaaacaa ttgggtaccc agttaaattt tcatttcaga taaacaacaa 1260 ataatttttt agtataagta cattattgtt tatctgaaat tttaattgaa ctaacaatcc 1320 tagtttgata ctcccagtct tgtcattgcc agctgtgttg gtagtgctgt gttgaattac 1380 ggaataatga gttagaacta ttaaaacagc caaaactcca cagtcaatat tagtaatttc 1440 ttgctggttg aaacttgttt attatgtaca aatagattct tataatatta tttaaatgac 1500 tgcattttta aatacaaggc tttatatttt taactttaag atgtttttat gtgctctcca 1560 aatttttttt actgtttctg attgtatgga aatataaaag taaatatgaa acatttaaaa 1620 tataatttgt tgtcaaagt 1639 <210> 176 <211> 1191 <212> DNA <213> HUMAN <400> 176 atgaactggc atctccccct cttcctcttg gcctctgtga cgctgccttc catctgctcc 60 cacttcaatc ctctgtctct cgaggaacta ggctccaaca cggggatcca ggttttcaat 120 cagattgtga agtcgaggcc tcatgacaac atcgtgatct ctccccatgg gattgcgtcg 180 gtcctgggga tgcttcagct gggggcggac ggcaggacca agaagcagct cgccatggtg 240 atgagatacg gcgtaaatgg agttggtaaa atattaaaga agatcaacaa ggccatcgtc 300 tccaagaaga ataaagacat tgtgacagtg gctaacgccg tgtttgttaa gaatgcctct 360 gaaattgaag tgccttttgt tacaaggaac aaagatgtgt tccagtgtga ggtccggaat 420 gtgaactttg aggatccagc ctctgcctgt gattccatca atgcatgggt taaaaacgaa 480 accagggata tgattgacaa tctgctgtcc ccagatctta ttgatggtgt gctcaccaga 540 ctggtcctcg tcaacgcagt gtatttcaag ggtctgtgga aatcacggtt ccaacccgag 600 aacacaaaga aacgcacttt cgtggcagcc gacgggaaat cctatcaagt gccaatgctg 660 gcccagctct ccgtgttccg gtgtgggtcg acaagtgccc ccaatgattt atggtacaac 720 ttcattgaac tgccctacca cggggaaagc atcagcatgc tgattgcact gccgactgag 780 agctccactc cgctgtctgc catcatccca cacatcagca ccaagaccat agacagctgg 840 atgagcatca tggtccccaa gagggtgcag gtgatcctgc ccaagttcac agctgtagca 900 caaacagatt tgaaggagcc gctgaaagtt cttggcatta ctgacatgtt tgattcatca 960 aaggcaaatt ttgcaaaaat aacaaggtca gaaaacctcc atgtttctca tatcttgcaa 1020 aaagcaaaaa ttgaagtcag tgaagatgga accaaagctt cagcagcaac aactgcaatt 1080 ctcattgcaa gatcatcgcc tccctggttt atagtagaca gaccttttct gtttttcatc 1140 cgacataatc ctacaggtgc tgtgttattc atggggcaga taaacaaacc c 1191 <210> 177 <211> 3215 <212> DNA <213> HUMAN <400> 177 gacaatatca ggtgagctgt ggaggtgggg tccttggaag ctggatgaca gcagctggca 60 aggggataag agagcagtga gcccctccct caaggaggtc tggctttatc catagacagg 120 gccctctgag gtggggctga ggtacaaagg gggattgagc agcccaggag aagagagatg 180 ggggttccct tcttctcttc tctcagatgc atggtggact taggaccttg ctgggctggg 240 ggtctcactg cagagatgaa gctgcttctg gccctagcag ggctcctggc cattctggcc 300 acgccccagc cctctgaagg tgctgctcca gctgtcctgg gggaggtgga cacctcgttg 360 gtgctgagct ccatggagga ggccaagcag ctggtggaca aggcctacaa ggagcggcgg 420 gaaagcatca agcagcggct tcgcagcggc tcagccagcc ccatggaact cctatcctac 480 ttcaagcagc cggtggcagc caccaggacg gcggtgaggg ccgctgacta cctgcacgtg 540 gctctagacc tgctggagag gaagctgcgg tccctgtggc gaaggccatt caatgtcact 600 gatgtgctga cgcccgccca gctgaatgtg ttgtccaagt caagcggctg cgcctaccag 660 gacgtggggg tgacttgccc ggagcaggac aaataccgca ccatcaccgg gatgtgcaac 720 aacagacgca gccccacgct gggggcctcc aaccgtgcct ttgtgcgctg gctgccggcg 780 gagtatgagg acggcttctc tcttccctac ggctggacgc ccggggtcaa gcgcaacggc 840 ttcccggtgg ctctggctcg cgcggtctcc aacgagatcg tgcgcttccc cactgatcag 900 ctgactccgg accaggagcg ctcactcatg ttcatgcaat ggggccagct gttggaccac 960 gacctcgact tcacccctga gccggccgcc cgggcctcct tcgtcactgg cgtcaactgc 1020 gagaccagct gcgttcagca gccgccctgc ttcccgctca agatcccgcc caatgacccc 1080 cgcatcaaga accaagccga ctgcatcccg ttcttccgct cctgcccggc ttgccccggg 1140 agcaacatca ccatccgcaa ccagatcaac gcgctcactt ccttcgtgga cgccagcatg 1200 gtgtacggca gcgaggagcc cctggccagg aacctgcgca acatgtccaa ccagctgggg 1260 ctgctggccg tcaaccagcg cttccaagac aacggccggg ccctgctgcc ctttgacaac 1320 ctgcacgatg acccctgtct cctcaccaac cgctcagcgc gcatcccctg cttcctggca 1380 ggggacaccc gttccagtga gatgcccgag ctcacctcca tgcacaccct cttacttcgg 1440 gagcacaacc ggctggccac agagctcaag agcctgaacc ctaggtggga tggggagagg 1500 ctctaccagg aagcccggaa gatcgtgggg gccatggtcc agatcatcac ttaccgggac 1560 tacctgcccc tggtgctggg gccaacggcc atgaggaagt acctgcccac gtaccgttcc 1620 tacaatgact cagtggaccc acgcatcgcc aacgtcttca ccaatgcctt ccgctacggc 1680 cacaccctca tccaaccctt catgttccgc ctggacaatc ggtaccagcc catggaaccc 1740 aacccccgtg tccccctcag cagggtcttt tttgcctcct ggagggtcgt gctggaaggt 1800 ggcattgacc ccatcctccg gggcctcatg gccacccctg ccaagctgaa tcgtcagaac 1860 caaattgcag tggatgagat ccgggagcga ttgtttgagc aggtcatgag gattgggctg 1920 gacctgcctg ctctgaacat gcagcgcagc agggaccacg gcctcccagg atacaatgcc 1980 tggaggcgct tctgtgggct cccgcagcct gaaactgtgg gccagctggg cacggtgctg 2040 aggaacctga aattggcgag gaaactgatg gagcagtatg gcacgcccaa caacatcgac 2100 atctggatgg gcggcgtgtc cgagcctctg aagcgcaaag gccgcgtggg cccactcctc 2160 gcctgcatca tcggtaccca gttcaggaag ctccgggatg gtgatcggtt ttggtgggag 2220 aacgagggtg tgttcagcat gcagcagcga caggccctgg cccagatctc attgccccgg 2280 atcatctgcg acaacacagg catcaccacc gtgtctaaga acaacatctt catgtccaac 2340 tcatatcccc gggactttgt caactgcagt acacttcctg cattgaacct ggcttcctgg 2400 agggaagcct cctagaggcc aggtaagggg gtgcagcagt gaggggtata tctgggctgg 2460 ccagttggaa ccacggagat ctccttgccc tagatgagcc cagccctgtt ctgggtgcag 2520 ctgagaaaat gagtgactag acgttcattt gtgtgctcat gtatgtgcga agtatataaa 2580 ttggcttttc atgcgtgtgt gttgtctgaa catggggagt gtttcatggg ttatgtgtat 2640 gtgccattta tgtgagtgtg tgtttgtgct gatgagaata ctgagtatgt ggaaggcagc 2700 agagcggact ggtgaggagc acagctcagg aactagactg cctgggttcc aatcctggct 2760 ctgtggcttg ctagctatgt gaccttgagc aaattaccct ccttaaacaa gagttttctt 2820 ccttgtaaat tacatctgtc atggtttctt ggagggccca cttgtatcct ctggttcttc 2880 atttattgag cacctactac atgcaaggca ctgtactagg cgtgagaagc atatagaggc 2940 aagaaagaga taccaagatg ccatctgtgt cctggttagc agagctggac cagtggtgcc 3000 ttggagggat aagccagctg cagctgggct gtgtggttga cttatgggcc cagccagcca 3060 ggctcaggcc atggctcccc tttttcttcc tcaccctgat ttcttgctta ttcactgaag 3120 ttctcctgaa gaggaactgg gcctgttgcc ctttctgtac catttatttg ctcccaatgt 3180 ttatgataat aaaggcaccg ctgatgggga cctcc 3215 <210> 178 <211> 3319 <212> DNA <213> HUMAN <400> 178 ggcggtcccc tgttctcccc gctcaggtgc ggcgctgtgg caggaagcca ccccctcggt 60 cggccggtgc gcggggctgt tgcgccatcc gctccggctt tcgtaaccgc accctgggac 120 ggcccagaga cgctccagcg cgagttcctc aaatgttttc ctgcgttgcc aggaccgtcc 180 gccgctctga gtcatgtgcg agtgggaagt cgcactgaca ctgagccggg ccagagggag 240 aggagccgag cgcggcgcgg ggccgaggga ctcgcagtgt gtgtagagag ccgggctcct 300 gcggatgggg gctgcccccg gggcctgagc ccgcctgccc gcccaccgcc ccgccccgcc 360 cctgccaccc ctgccgcccg gttcccatta gcctgtccgc ctctgcggga ccatggagtg 420 gtagccgagg aggaagcatg ctggccgtcg gctgcgcgct gctggctgcc ctgctggccg 480 cgccgggagc ggcgctggcc ccaaggcgct gccctgcgca ggaggtggca agaggcgtgc 540 tgaccagtct gccaggagac agcgtgactc tgacctgccc gggggtagag ccggaagaca 600 atgccactgt tcactgggtg ctcaggaagc cggctgcagg ctcccacccc agcagatggg 660 ctggcatggg aaggaggctg ctgctgaggt cggtgcagct ccacgactct ggaaactatt 720 catgctaccg ggccggccgc ccagctggga ctgtgcactt gctggtggat gttccccccg 780 aggagcccca gctctcctgc ttccggaaga gccccctcag caatgttgtt tgtgagtggg 840 gtcctcggag caccccatcc ctgacgacaa aggctgtgct cttggtgagg aagtttcaga 900 acagtccggc cgaagacttc caggagccgt gccagtattc ccaggagtcc cagaagttct 960 cctgccagtt agcagtcccg gagggagaca gctctttcta catagtgtcc atgtgcgtcg 1020 ccagtagtgt cgggagcaag ttcagcaaaa ctcaaacctt tcagggttgt ggaatcttgc 1080 agcctgatcc gcctgccaac atcacagtca ctgccgtggc cagaaacccc cgctggctca 1140 gtgtcacctg gcaagacccc cactcctgga actcatcttt ctacagacta cggtttgagc 1200 tcagatatcg ggctgaacgg tcaaagacat tcacaacatg gatggtcaag gacctccagc 1260 atcactgtgt catccacgac gcctggagcg gcctgaggca cgtggtgcag cttcgtgccc 1320 aggaggagtt cgggcaaggc gagtggagcg agtggagccc ggaggccatg ggcacgcctt 1380 ggacagaatc caggagtcct ccagctgaga acgaggtgtc cacccccatg caggcactta 1440 ctactaataa agacgatgat aatattctct tcagagattc tgcaaatgcg acaagcctcc 1500 cagtgcaaga ttcttcttca gtaccactgc ccacattcct ggttgctgga gggagcctgg 1560 ccttcggaac gctcctctgc attgccattg ttctgaggtt caagaagacg tggaagctgc 1620 gggctctgaa ggaaggcaag acaagcatgc atccgccgta ctctttgggg cagctggtcc 1680 cggagaggcc tcgacccacc ccagtgcttg ttcctctcat ctccccaccg gtgtccccca 1740 gcagcctggg gtctgacaat acctcgagcc acaaccgacc agatgccagg gacccacgga 1800 gcccttatga catcagcaat acagactact tcttccccag atagctggct gggtggcacc 1860 agcagcctgg accctgtgga tgacaaaaca caaacgggct cagcaaaaga tgcttctcac 1920 tgccatgcca gcttatctca ggggtgtgcg gcctttggct tcacggaaga gccttgcgga 1980 aggttctacg ccaggggaaa atcagcctgc tccagctgtt cagctggttg aggtttcaaa 2040 cctccctttc caaatgccca gcttaaaggg gttagagtga acttgggcca ctgtgaagag 2100 aaccatatca agactctttg gacactcaca cggacactca aaagctgggc aggttggtgg 2160 gggcctcggt gtggagaagc ggctggcagc ccacccctca acacctctgc acaagctgca 2220 ccctcaggca ggtgggatgg atttccagcc aaagcctcct ccagccgcca tgctcctggc 2280 ccactgcatc gtttcatctt ccaactcaaa ctcttaaaac ccaagtgccc ttagcaaatt 2340 ctgtttttct aggcctgggg acggctttta cttaaacgcc aaggcctggg ggaagaagct 2400 ctctcctccc tttcttccct acagttcaaa aacagctgag ggtgagtggg tgaataatac 2460 agtatgtcag ggcctggtcg ttttcaacag aattataatt agttcctcat tagcagtttt 2520 gcctaaatgt gaatgatgat cctaggcatt tgctgaatac agaggcaact gcattggctt 2580 tgggttgcag gacctcaggt gagaagcaga ggaaggagag gagaggggca cagggtctct 2640 accatcccct gtagagtggg agctgagtgg gggatcacag cctctgaaaa ccaatgttct 2700 ctcttctcca cctcccacaa aggagagcta gcagcaggga gggcttctgc catttctgag 2760 atcaaaacgg ttttactgca gctttgtttg ttgtcagctg aacctgggta actagggaag 2820 ataatattaa ggaagacaat gtgaaaagaa aaatgagcct ggcaagaatg cgtttaaact 2880 tggtttttaa aaaactgctg actgttttct cttgagaggg tggaatatcc aatattcgct 2940 gtgtcagcat agaagtaact tacttaggtg tgggggaagc accataactt tgtttagccc 3000 aaaaccaagt caagtgaaaa aggaggaaga gaaaaaatat tttcctgcca ggcatggagg 3060 cccacgcact tcgggaggtc gaggcaggag gatcacttga gtccagaagt ttgagatcag 3120 cctgggcaat gtgataaaac cccatctcta caaaaagcat aaaaattagc caagtgtggt 3180 agagtgtgcc tgaagtccca gatacttggg gggctgaggt gggaggatct cttgagcctg 3240 ggaggtcaag gctgcagtga gccgagattg caccactgca ctccagcctg gggtgacaga 3300 gcaagtgaga ccctgtctc 3319 <210> 179 <211> 856 <212> DNA <213> HUMAN <400> 179 cttgttcggg gcgctccgct ggcttcttgg acaattgcgc catgtgtgct gctcggctag 60 cggcggcggc ggcccagtcg gtgtatgcct tctcggcgcg cccgttggcc ggcggggagc 120 ctgtgagcct gggctccctg cggggcaagg tactacttat cgagaatgtg gcgtccctct 180 gaggcaccac ggtccgggac tacacccaga tgaacgagct gcagcggcgc ctcggacccc 240 ggggcctggt ggtgctcggc ttcccgtgca accagtttgg gcatcaggag aacgccaaga 300 acgaagagat tctgaattcc ctcaagtacg tccggcctgg tggtgggttc gagcccaact 360 tcatgctctt cgagaagtgc gaggtgaacg gtgcgggggc gcaccctctc ttcgccttcc 420 tgcgggaggc cctgccagct cccagcgacg acgccaccgc gcttatgacc gaccccaagc 480 tcatcacctg gtctccggtg tgtcgcaacg atgttgcctg gaactttgag aagttcctgg 540 tgggccctga cggtgtgccc ctacgcaggt acagccgccg cttccagacc attgacatcg 600 agcctgacat cgaagccctg ctgtctcaag ggcccagctg tgcctagggc gcccctccta 660 ccccggctgc ttggcagttg cagtgctgct gtctcggggg ggttttcatc tatgagggtg 720 tttcctctaa acctacgagg gaggaacacc ttgatcttac agaaaatacc acctcgagat 780 gggtgctggt cctgttgatc ccagtctctg ccagaccaag gcgagtttcc ccactaataa 840 agtgccgggt gtcagc 856 <210> 180 <211> 369 <212> DNA <213> HUMAN <400> 180 atgaagcttc tcacgggcct ggttttctgc tccttggtcc tgagtgtcag cagccgaagc 60 ttcttttcgt tccttggcga ggcttttgat ggggctcggg acatgtggag agcctactct 120 gacatgagag aagccaatta catcggctca gacaaatact tccatgctcg ggggaactat 180 gatgctgcca aaaggggacc tgggggtgcc tgggccgcag aagtgatcag caatgccaga 240 gagaatatcc agagactcac aggccatggt gcggaggact cgctggccga tcaggctgcc 300 aataaatggg gcaggagtgg cagagacccc aatcacttcc gacctgctgg cctgcctgag 360 aaatactga 369 <210> 181 <211> 4910 <212> DNA <213> HUMAN <400> 181 tagacgcacc ctctgaagat ggtgactccc tcctgagaag ctggacccct tggtaaaaga 60 caaggccttc tccaagaaga atatgaaagt gttactcaga cttatttgtt tcatagctct 120 actgatttct tctctggagg ctgataaatg caaggaacgt gaagaaaaaa taattttagt 180 gtcatctgca aatgaaattg atgttcgtcc ctgtcctctt aacccaaatg aacacaaagg 240 cactataact tggtataaag atgacagcaa gacacctgta tctacagaac aagcctccag 300 gattcatcaa cacaaagaga aactttggtt tgttcctgct aaggtggagg attcaggaca 360 ttactattgc gtggtaagaa attcatctta ctgcctcaga attaaaataa gtgcaaaatt 420 tgtggagaat gagcctaact tatgttataa tgcacaagcc atatttaagc agaaactacc 480 cgttgcagga gacggaggac ttgtgtgccc ttatatggag ttttttaaaa atgaaaataa 540 tgagttacct aaattacagt ggtataagga ttgcaaacct ctacttcttg acaatataca 600 ctttagtgga gtcaaagata ggctcatcgt gatgaatgtg gctgaaaagc atagagggaa 660 ctatacttgt catgcatcct acacatactt gggcaagcaa tatcctatta cccgggtaat 720 agaatttatt actctagagg aaaacaaacc cacaaggcct gtgattgtga gcccagctaa 780 tgagacaatg gaagtagact tgggatccca gatacaattg atctgtaatg tcaccggcca 840 gttgagtgac attgcttact ggaagtggaa tgggtcagta attgatgaag atgacccagt 900 gctaggggaa gactattaca gtgtggaaaa tcctgcaaac aaaagaagga gtaccctcat 960 cacagtgctt aatatatcgg aaattgaaag tagattttat aaacatccat ttacctgttt 1020 tgccaagaat acacatggta tagatgcagc atatatccag ttaatatatc cagtcactaa 1080 tttccagaag cacatgattg gtatatgtgt cacgttgaca gtcataattg tgtgttctgt 1140 tttcatctat aaaatcttca agattgacat tgtgctttgg tacagggatt cctgctatga 1200 ttttctccca ataaaagctt cagatggaaa gacctatgac gcatatatac tgtatccaaa 1260 gactgttggg gaagggtcta cctctgactg tgatattttt gtgtttaaag tcttgcctga 1320 ggtcttggaa aaacagtgtg gatataagct gttcatttat ggaagggatg actacgttgg 1380 ggaagacatt gttgaggtca ttaatgaaaa cgtaaagaaa agcagaagac tgattatcat 1440 tttagtcaga gaaacatcag gcttcagctg gctgggtggt tcatctgaag agcaaatagc 1500 catgtataat gctcttgttc aggatggaat taaagttgtc ctgcttgagc tggagaaaat 1560 ccaagactat gagaaaatgc cagaatcgat taaattcatt aagcagaaac atggggctat 1620 ccgctggtca ggggacttta cacagggacc acagtctgca aagacaaggt tctggaagaa 1680 tgtcaggtac cacatgccag tccagcgacg gtcaccttca tctaaacacc agttactgtc 1740 accagccact aaggagaaac tgcaaagaga ggctcacgtg cctctcgggt agcatggaga 1800 agttgccaag agttctttag gtgcctcctg tcttatggcg ttgcaggcca ggttatgcct 1860 catgctgact tgcagagttc atggaatgta actatatcat cctttatccc tgaggtcacc 1920 tggaatcaga ttattaaggg aataagccat gacgtcaata gcagcccagg gcacttcaga 1980 gtagagggct tgggaagatc ttttaaaaag gcagtaggcc cggtgtggtg gctcacgcct 2040 ataatcccag cactttggga ggctgaagtg ggtggatcac cagaggtcag gagttcgaga 2100 ccagcccagc caacatggca aaaccccatc tctactaaaa atacaaaaat gagctaggca 2160 tggtggcaca cgcctgtaat cccagctaca cctgaggctg aggcaggaga attgcttgaa 2220 ccggggagac ggaggttgca gtgagccgag tttgggccac tgcactctag cctggcaaca 2280 gagcaagact ccgtctcaaa aaaagggcaa taaatgccct ctctgaatgt ttgaactgcc 2340 aagaaaaggc atggagacag cgaactagaa gaaagggcaa gaaggaaata gccaccgtct 2400 acagatggct tagttaagtc atccacagcc caagggcggg gctatgcctt gtctggggac 2460 cctgtagagt cactgaccct ggagcggctc tcctgagagg tgctgcaggc aaagtgagac 2520 tgacacctca ctgaggaagg gagacatatt cttggagaac tttccatctg cttgtatttt 2580 ccatacacat ccccagccag aagttagtgt ccgaagaccg aattttattt tacagagctt 2640 gaaaactcac ttcaatgaac aaagggattc tccaggattc caaagttttg aagtcatctt 2700 agctttccac aggagggaga gaacttaaaa aagcaacagt agcagggaat tgatccactt 2760 cttaatgctt tcctccctgg catgaccatc ctgtcctttg ttattatcct gcattttacg 2820 tctttggagg aacagctccc tagtggcttc ctccgtctgc aatgtccctt gcacagccca 2880 cacatgaacc atccttccca tgatgccgct cttctgtcat cccgctcctg ctgaaacacc 2940 tcccaggggc tccacctgtt caggagctga agcccatgct ttcccaccag catgtcactc 3000 ccagaccacc tccctgccct gtcctccagc ttcccctcgc tgtcctgctg tgtgaattcc 3060 caggttggcc tggtggccat gtcgcctgcc cccagcactc ctctgtctct gctcttgcct 3120 cgacccttcc tcctcctttg cctaggaggc cttctcgcat tttctctagc tgatcagaat 3180 tttaccaaaa ttcagaacat cctccaattc cacagtctct gggagacttt ccctaagagg 3240 cgacttcctc tccagccttc tctctctggt caggcccact gcagagatgg tggtgagcac 3300 atctgggagg ctggtctccc tccagctgga attgctgctc tctgagggag aggctgtggt 3360 ggctgtctct gtccctcact gccttccagg agcaatttgc acatgtaaca tagatttatg 3420 taatgcttta tgtttaaaaa cattccccaa ttatcttatt taatttttgc aattattcta 3480 attttatata tagagaaagt gacctatttt ttaaaaaaat cacactctaa gttctattga 3540 acctaggact tgagcctcca tttctggctt ctagtctggt gttctgagta cttgatttca 3600 ggtcaataac ggtcccccct cactccacac tggcacgttt gtgagaagaa atgacatttt 3660 gctaggaagt gaccgagtct aggaatgctt ttattcaaga caccaaattc caaacttcta 3720 aatgttggaa ttttcaaaaa ttgtgtttag attttatgaa aaactcttct actttcatct 3780 attctttccc tagaggcaaa catttcttaa aatgtttcat tttcattaaa aatgaaagcc 3840 aaatttatat gccaccgatt gcaggacaca agcacagttt taagagttgt atgaacatgg 3900 agaggacttt tggtttttat atttctcgta tttaatatgg gtgaacacca acttttattt 3960 ggaataataa ttttcctcct aaacaaaaac acattgagtt taagtctctg actcttgcct 4020 ttccacctgc tttctcctgg gcccgctttg cctgcttgaa ggaacagtgc tgttctggag 4080 ctgctgttcc aacagacagg gcctagcttt catttgacac acagactaca gccagaagcc 4140 catggagcag ggatgtcacg tcttgaaaag cctattagat gttttacaaa tttaattttg 4200 cagattattt tagtctgtca tccagaaaat gtgtcagcat gcatagtgct aagaaagcaa 4260 gccaatttgg aaacttaggt tagtgacaaa attggccaga gagtgggggt gatgatgacc 4320 aagaattaca agtagaatgg cagctggaat ttaaggaggg acaagaatca atggataagc 4380 gtgggtggag gaagatccaa acagaaaagt gcaaagttat tccccatctt ccaagggttg 4440 aattctggag gaagaagaca cattcctagt tccccgtgaa cttcctttga cttattgtcc 4500 ccactaaaac aaaacaaaaa acttttaatg ccttccacat taattagatt ttcttgcagt 4560 ttttttatgg cattttttta aagatgccct aagtgttgaa gaagagtttg caaatgcaac 4620 aaaaatattt aattaccggt tgttaaaact ggtttagcac aatttatatt ttccctctct 4680 tgcctttctt atttgcaata aaaggtattg agccattttt taaatgacat ttttgataaa 4740 ttatgtttgt actagttgat gaaggagttt tttttaacct gtttatataa ttttgcagca 4800 gaagccaaat tttttgtata ttaaagcacc aaattcatgt acagcatgca tcacggatca 4860 atagactgta cttattttcc aataaaattt tcaaactttg tactgttaaa 4910 <210> 182 <211> 579 <212> DNA <213> HUMAN <400> 182 atgcaggcca tcaagtgtgt ggtggtggga gacggagctg taggtaaaac ttgcctactg 60 atcagttaca caaccaatgc atttcctgga gaatatatcc ctactgtctt tgacaattat 120 tctgccaatg ttatggtaga tggaaaaccg gtgaatctgg gcttatggga tacagctgga 180 caagaagatt atgacagatt acgcccccta tcctatccgc aaacagatgt gttcttaatt 240 tgcttttccc ttgtgagtcc tgcatcattt gaaaatgtcc gtgcaaagtg gtatcctgag 300 gtgcggcacc actgtcccaa cactcccatc atcctagtgg gaactaaact tgatcttagg 360 gatgataaag acacgatcga gaaactgaag gagaagaagc tgactcccat cacctatccg 420 cagggtctag ccatggctaa ggagattggt gctgtaaaat acctggagtg ctcggcgctc 480 acacagcgag gcctcaagac agtgtttgac gaagcgatcc gagcagtcct ctgcccgcct 540 cccgtgaaga agaggaagag aaaatgcctg ctgttgtaa 579 <210> 183 <211> 579 <212> DNA <213> HUMAN <400> 183 atgcaggcca tcaagtgtgt ggtggtggga gatggggccg tgggcaagac ctgccttctc 60 atcagctaca ccaccaacgc ctttcccgga gagtacatcc ccaccgtgtt tgacaactat 120 tcagccaatg tgatggtgga cagcaagcca gtgaacctgg ggctgtggga cactgctggg 180 caggaggact acgaccgtct ccggccgctc tcctatccac agacggacgt cttcctcatc 240 tgcttctccc tcgtcagccc agcctcttat gagaacgtcc gcgccaagtg gttcccagaa 300 gtgcggcacc actgccccag cacacccatc atcctggtgg gcaccaagct ggacctgcgg 360 gacgacaagg acaccatcga gaaactgaag gagaagaagc tggctcccat cacctacccg 420 cagggcctgg cactggccaa ggagattgac tcggtgaaat acctggagtg ctcagccctc 480 acccagagag gcctgaaaac cgtgttcgac gaggccatcc gggccgtgct gtgccctcag 540 cccacgcggc agcagaagcg cgcctgcagc ctcctctag 579 <210> 184 <211> 2277 <212> DNA <213> HUMAN <400> 184 acatggcgaa cgaggttatc aagtgcaagg ctgcagttgc ttgggaggct ggaaagcctc 60 tctccataga ggagatagag gtggcacccc caaaggctca tgaagttcga atcaagatca 120 ttgccactgc ggtttgccac accgatgcct ataccctgag tggagctgat cctgagggtt 180 gttttccagt gatcttggga catgaaggtg ctggaattgt ggaaagtgtt ggtgagggag 240 ttactaagct gaaggcgggt gacactgtca tcccacttta catcccacag tgtggagaat 300 gcaaattttg tctaaatcct aaaactaacc tttgccagaa gataagagtc actcaaggga 360 aaggattaat gccagatggt accagcagat ttacttgcaa aggaaagaca attttgcatt 420 acatgggaac cagcacattt tctgaataca cagttgtggc tgatatctct gttgctaaaa 480 tagatccttt agcacctttg gataaagtct gccttctagg ttgtggcatt tcaaccggtt 540 atggtgctgc tgtgaacact gccaagttgg agcctggctc tgtttgtgcc gtctttggtc 600 tgggaggagt cggattggca gttatcatgg gctgtaaagt ggctggtgct tcccggatca 660 ttggtgtgga catcaataaa gataaatttg caagggccaa agagtttgga gccactgaat 720 gtattaaccc tcaggatttt agtaaaccca tccaggaagt gctcattgag atgaccgatg 780 gaggagtgga ctattccttt gaatgtattg gtaatgtgaa ggtcatgaga gcagcacttg 840 aggcatgtca caagggctgg ggcgtcagcg tcgtggttgg agtagctgct tcaggtgaag 900 aaattgccac tcgtccattc cagctggtaa caggtcgcac atggaaaggc actgcctttg 960 gaggatggaa gagtgtagaa agtgtcccaa agttggtgtc tgaatatatg tccaaaaaga 1020 taaaagttga tgaatttgtg actcacaatc tgtcttttga tgaaatcaac aaagcctttg 1080 aactgatgca ttctggaaag agcattcgaa ctgttgtaaa gatttaattc aaaagagaaa 1140 aataatgtcc atcctgtcgt gatgtgatag gagcagctta acaggcaggg agaagcgcct 1200 ccaacctcac agcctcgtag agcttcacag ctactccaga aaatagggtt atgtgtgtca 1260 ttcatgaatc tctataatca aggacaagga taattcagtc atgaacctgt tttctggatg 1320 ctcctccaca taaataattg ctagtttatt aaggaatatt ttaacataat aaaagtaatt 1380 tctacatttg tgtggaaatt gtcttgtttt atgctgtcat cattgtcacg gttgtctgcc 1440 attatcttca ttctgcaagg gaaagggaaa ggaagcaggg cagtggtggg tgtctgaaac 1500 ctcagaaaca taacgttgaa cttttaaggg tctcagtccc cgttgattaa agaacagatc 1560 ctagccatca gtgacaaagt taatcaggac ccaagtctgc ttctgtgata ttatcttgaa 1620 gggaggtact gtgccttgtt catacctgta ccccaaattc ctaggatgca tctgccttca 1680 gggggcacta aaatgtatta ttgaaacagc attctgggct taaataggtg tatgtatgtg 1740 ttggttgtga ctgtactatt ctagtatagt gaactacata ctgaatatcc aagttctcag 1800 cacctacttt tgtcaaatct taacattttg ccacttcgag atcacattgc cttcctcccc 1860 tccaagaggt aacaattatc cacaatttga tgtttatcat tcctgtgttg ttgtactttc 1920 actgtgtata acctaaacca tctactcttt agtactgttt tatatatttt taagcctcat 1980 acttgctcat tctacagctt ttttcactca ttattgtata attatatctg aagctctcgt 2040 tcattaattt tagtcctgtg tagcagaatt caattacggg aaactaccat aatttatctg 2100 ttctccagtc cagttgaagg catgaagttg ttgccagttt ctgtattata acactgtagt 2160 ggaacattct tctgcattgg gctactcgcg tgttacctaa gacgtatcac agaataaaca 2220 catttagcct tatagacatt gccaaattgc tcttcaaagt aaatgtgagt ttttgtg 2277 <210> 185 <211> 1230 <212> DNA <213> HUMAN <400> 185 agacgttcgc acacctgggt gccagcgccc cagaggtccc gggacagccc gaggcgccgc 60 gcccgccgcc ccgagctccc caagccttcg agagcggcgc acactcccgg tctccactcg 120 ctcttccaac acccgctcgt tttgcggcag ctcgtgtccc agagaccgag ttgccccaga 180 gaccgagacg ccgccgctgc gaaggaccaa tgagagcccc gctgctaccg ccggcgccgg 240 tggtgctgtc gctcttgata ctcggctcag gccattatgc tgctggattg gacctcaatg 300 acacctactc tgggaagcgt gaaccatttt ctggggacca cagtgctgat ggatttgagg 360 ttacctcaag aagtgagatg tcttcaggga gtgagatttc ccctgtgagt gaaatgcctt 420 ctagtagtga accgtcctcg ggagccgact atgactactc agaagagtat gataacgaac 480 cacaaatacc tggctatatt gtcgatgatt cagtcagagt tgaacaggta gttaagcccc 540 cccaaaacaa gacggaaagt gaaaatactt cagataaacc caaaagaaag aaaaagggag 600 gcaaaaatgg aaaaaataga agaaacagaa agaagaaaaa tccatgtaat gcagaatttc 660 aaaatttctg cattcacgga gaatgcaaat atatagagca cctggaagca gtaacatgca 720 aatgtcagca agaatatttc ggtgaacggt gtggggaaaa gtccatgaaa actcacagca 780 tgattgacag tagtttatca aaaattgcat tagcagccat agctgccttt atgtctgctg 840 tgatcctcac agctgttgct gttattacag tccagcttag aagacaatac gtcaggaaat 900 atgaaggaga agctgaggaa cgaaagaaac ttcgacaaga gaatggaaat gtacatgcta 960 tagcataact gaagataaaa ttacaggata tcacattgga gtcactgcca agtcatagcc 1020 ataaatgatg agtcggtcct ctttccagtg gatcataaga caatggaccc tttttgttat 1080 gatggtttta aactttcaat tgtcactttt tatgctattt ctgtatataa aggtgcacga 1140 aggtaaaaag tattttttca agttgtaaat aatttattta atatttaatg gaagtgtatt 1200 tattttacag ctcattaaac ttttttaacc 1230 <210> 186 <211> 1818 <212> DNA <213> HUMAN <400> 186 tagtctggag ctatggtggt ggtggcagcc gcgccgaacc cggccgacgg gacccctaaa 60 gttctgcttc tgtcggggca gcccgcctcc gccgccggag ccccggcggc caggctgccg 120 ctcatggtgc cagcccagag aggggccagc ccggaggcag cgagcggggg gctgccccag 180 gcgcgcaagc gacagcgcct cacgcacctg agccccgagg agaaggcgct gaggaggaaa 240 ctgaaaaaca gagtagcagc tcagactgcc agagatcgaa agaaggctcg aatgagtgag 300 ctggaacagc aagtggtaga tttagaagaa gagaaccaaa aacttttgct agaaaatcag 360 cttttacgag agaaaactca tggccttgta gttgagaacc aggagttaag acagcgcttg 420 gggatggatg ccctggttgc tgaagaggag gcggaagcca aggggaatga agtgaggcca 480 gtggccgggt ctgctgagtc cgcagcactc agactacgtg cacctctgca gcaggtgcag 540 gcccagttgt cacccctcca gaacatctcc ccatggattc tggcggtatt gactcttcag 600 attcagagtc tgatatcctg ttgggcattc tggacaactt ggacccagtc atgttcttca 660 aatgcccttc cccagagcct gccagcctgg aggagctccc agaggtctac ccagaaggac 720 ccagttcctt accagcctcc ctttctctgt cagtggggac gtcatcagcc aagctggaag 780 ccattaatga actaattcgt tttgaccaca tatataccaa gcccctagtc ttagagatac 840 cctctgagac agagagccaa gctaatgtgg tagtgaaaat cgaggaagca cctctcagcc 900 cctcagagaa tgatcaccct gaattcattg tctcagtgaa ggaagaacct gtagaagatg 960 acctcgttcc ggagctgggt atctcaaatc tgctttcatc cagccactgc ccaaagccat 1020 cttcctgcct actggatgct acagtgactg tggatacggg ggttcccttt ccccattcag 1080 tgacatgtcc tctctgcttg gtgtaaacat tcttgggagg acacttttgc caatgaactc 1140 tttccccagc tgattagtgt ctaaggaatg atccaatact gttgcccttt tccttgacta 1200 ttacactgcc tggaggatag cagagaagcc tgtctgtact tcattcaaaa agccaaaata 1260 gagagtatac agtcctagag aatccctcta tttgttcaga tctcatagat gacccccagg 1320 tattgccttt tgacatccag cagtccaagg tattgagaca tattactgga agtaagaaat 1380 attactataa ttgagaacta cagcttttaa gattgtactt ttaagattgt acttttatct 1440 taaaagggtg gtagttttcc ctaaaatact tattatgtaa gggtcattag acaaatgtct 1500 tgaagtagac atggaattta tgaatggtct ttatcatttc tcttccccct ttttggcatc 1560 ctggcttgcc tccagtttta ggtcctttag tttgcttctg caagcaacgg gaacacctgc 1620 tgagggggct ctttccctca tgtatacttc aagtaagatc aagaatcttt tgtgaaatta 1680 tagaaattta ctatgtaaat gcttgatgga attttttcct gctagtgtag cttctgaaag 1740 gtgctttctc catttattta aaaactaccc atgcaattaa aaggtacaat gcaaaaaaaa 1800 aaaaaaaaaa attttttt 1818 <210> 187 <211> 1035 <212> DNA <213> HUMAN <400> 187 gaattccggc ccgccgtccc ccaccccgcc gccccgcccg gcgaattgcg ccccgcgccc 60 ctcccctcgc gcccccgaga caaagaggag agaaagtttg cgcggccgag cggggcaggt 120 gaggagggtg agccgcgcgg gaggggcccg cctcggcccc ggctcagccc ccgcccgcgc 180 ccccagcccg ccgccgcgag cagcgcccgg accccccagc ggcggccccc gcccgcccag 240 ccccccggcc cgccatgggc gccgcggccc gcaccctgcg gctggcgctc ggcctcctgc 300 tgctggcgac gctgcttcgc ccggccgacg cctgcagctg ctccccggtg cacccgcaac 360 aggcgttttg caatgcagat gtagtgatca gggccaaagc ggtcagtgag aaggaagtgg 420 actctggaaa cgacatttat ggcaacccta tcaagaggat ccagtatgag atcaagcaga 480 taaagatgtt caaagggcct gagaaggata tagagtttat ctacacggcc ccctcctcgg 540 cagtgtgtgg ggtctcgctg gacgttggag gaaagaagga atatctcatt gcaggaaagg 600 ccgaggggga cggcaagatg cacatcaccc tctgtgactt catcgtgccc tgggacaccc 660 tgagcaccac ccagaagaag agcctgaacc acaggtacca gatgggctgc gagtgcaaga 720 tcacgcgctg ccccatgatc ccgtgctaca tctcctcccc ggacgagtgc ctctggatgg 780 actgggtcac agagaagaac atcaacgggc accaggccaa gttcttcgcc tgcatcaaga 840 gaagtgacgg ctcctgtgcg tggtaccgcg gcgcggcgcc ccccaagcag gagtttctcg 900 acatcgagga cccataagca ggcctccaac gcccctgtgg ccaactgcaa aaaaagcctc 960 caagggtttc gactggtcca gctctgacat cccttcctgg aaacagcatg aataaaacac 1020 tcatccccgg aattc 1035 <210> 188 <211> 2087 <212> DNA <213> HUMAN <400> 188 ctttggggtt caagatcact gggaccaggc cgtgatctct atgcccgagt ctcaaccctc 60 aactgtcacc ccaaagcact tgggacgtcc tggacagacc gagtcccggg aagccccagc 120 actgccgctg ccacactgcc ctgagcccaa atgggggagt gagaggccat agctgtctgg 180 catgggcctc tccaccgtgc ctgacctgct gctgccgctg gtgctcctgg agctgttggt 240 gggaatatac ccctcagggg ttattggact ggtccctcac ctaggggaca gggagaagag 300 agatagtgtg tgtccccaag gaaaatatat ccaccctcaa aataattcga tttgctgtac 360 caagtgccac aaaggaacct acttgtacaa tgactgtcca ggcccggggc aggatacgga 420 ctgcagggag tgtgagagcg gctccttcac cgcttcagaa aaccacctca gacactgcct 480 cagctgctcc aaatgccgaa aggaaatggg tcaggtggag atctcttctt gcacagtgga 540 ccgggacacc gtgtgtggct gcaggaagaa ccagtaccgg cattattgga gtgaaaacct 600 tttccagtgc ttcaattgca gcctctgcct caatgggacc gtgcacctct cctgccagga 660 gaaacagaac accgtgtgca cctgccatgc aggtttcttt ctaagagaaa acgagtgtgt 720 ctcctgtagt aactgtaaga aaagcctgga gtgcacgaag ttgtgcctac cccagattga 780 gaatgttaag ggcactgagg actcaggcac cacagtgctg ttgcccctgg tcattttctt 840 tggtctttgc cttttatccc tcctcttcat tggtttaatg tatcgctacc aacggtggaa 900 gtccaagctc tactccattg tttgtgggaa atcgacacct gaaaaagagg gggagcttga 960 aggaactact actaagcccc tggccccaaa cccaagcttc agtcccactc caggcttcac 1020 ccccaccctg ggcttcagtc ccgtgcccag ttccaccttc acctccagct ccacctatac 1080 ccccggtgac tgtcccaact ttgcggctcc ccgcagagag gtggcaccac cctatcaggg 1140 ggctgacccc atccttgcga cagccctcgc ctccgacccc atccccaacc cccttcagaa 1200 gtgggaggac agcgcccaca agccacagag cctagacact gatgaccccg cgacgctgta 1260 cgccgtggtg gagaacgtgc ccccgttgcg ctggaaggaa ttcgtgcggc gcctagggct 1320 gagcgaccac gagatcgatc ggctggagct gcagaacggg cgctgcctgc gcgaggcgca 1380 atacagcatg ctggcgacct ggaggcggcg cacgccgcgg cgcgaggcca cgctggagct 1440 gctgggacgc gtgctccgcg acatggacct gctgggctgc ctggaggaca tcgaggaggc 1500 gctttgcggc cccgccgccc tcccgcccgc gcccagtctt ctcagatgag gctgcgccct 1560 gcgggcagct ctaaggaccg tcctgcgaga tcgccttcca accccacttt tttctggaaa 1620 ggaggggtcc tgcaggggca agcaggagct agcagccgcc tacttggtgc taacccctcg 1680 atgtacatag cttttctcag ctgcctgcgc gccgccgaca gtcagcgctg tgcgcgcgga 1740 gagaggtgcg ccgtgggctc aagagcctga gtgggtggtt tgcgaggatg agggacgcta 1800 tgcctcatgc ccgttttggg tgtcctcacc agcaaggctg ctcgggggcc cctggttcgt 1860 ccctgagcct ttttcacagt gcataagcag ttttttttgt ttttgttttg ttttgttttg 1920 tttttaaatc aatcatgtta cactaataga aacttggcac tcctgtgccc tctgcctgga 1980 caagcacata gcaagctgaa ctgtcctaag gcaggggcga gcacggaaca atggggcctt 2040 cagctggagc tgtggacttt tgtacataca ctaaaattct gaagtta 2087 <210> 189 <211> 1080 <212> DNA <213> HUMAN <400> 189 cgcatctgca cctgcaggcc cggctggtac tgcgcgctga gcaagcagga ggggtgccgg 60 ctgtgcgcgc cgctgccgaa gtgccgcccg ggcttcggcg tggccagacc aggaactgaa 120 acatcagacg tggtgtgcaa gccctgtgcc ccggggacgt tctccaacac gacttcatcc 180 acggatattt gcaggcccca ccagatctgt aacgtggtgg ccatccctgg gaatgcaagc 240 agggatgcag tctgcacgtc cacgtccccc acccggagta tggccccagg ggcagtacac 300 ttaccccagc cagtgtccac acgatcccaa cacacgcagc caactccaga acccagcact 360 gctccaagca cctccttcct gctcccaatg ggccccagcc ccccagctga agggagcact 420 ggcgacttcg ctcttccagt tggactgatt gtgggtgtga cagccttggg tctactaata 480 ataggagtgg tgaactgtgt catcatgacc caggtgaaaa agaagccctt gtgcctgcag 540 agagaagcca aggtgcctca cttgcctgcc gataaggccc ggggtacaca gggccccgag 600 cagcagcacc tgctgatcac agcgccgagc tccagcagca gctccctgga gagctcggcc 660 agtgcgttgg acagaagggc gcccactcgg aaccagccac aggcaccagg cgtggaggcc 720 agtggggccg gggaggcgag gaccagcacc gggagctcag attcttcccc tggtggccat 780 gggacccagg tcaatgtcac ctgcatcgtg aacgtctgta gcagctctga ccacagctca 840 cagtgctcct cccaagccag ctccacaatg ggagacacag attccagccc ctcggagtcc 900 ccgaaggacg agcaggtccc cttctccaag gaggaatgtg cctttcggtc acagctggag 960 acgccagaga ccctgctggg gagcaccgaa gagaagcccc tgccccttgg agtgcctgat 1020 gctgggatga agcccagtta accaggccgg tgtgggctgt gtcgtagcca aggtgggctg 1080 <210> 190 <211> 741 <212> DNA <213> HUMAN <400> 190 gagaaatttt tcattttctt tcttgtttga ctgtatgcaa acatcaaact aagaatggca 60 aagatgaatc tctcttccta tatattaata ctaacttttt ctttgttttc tcaaggtatt 120 ttactttcag catccaagtc cataagaaat ttagatgatg acatggtatt taatacattc 180 aggttgggga aaggctttca gaaggaagac actgcagaaa aatcagttat tgctccttcc 240 ctggaacaat ataaaaatga tgagagcagt ttcatgaacg aagaggaaaa taaagtttca 300 aagaacacag gctccaaaca taatttctta aatcatggtc tgccactcaa tctggctata 360 aaaggatatc aagcactaaa aggatctgta gatttcccag ctgagaatgg agttcagaat 420 actgaatcaa cacaagaaaa gagagaaatt ggggatgaag aaaactcagc taaatttcct 480 ataggaagga gagattttga catgctcaga tgtatgctcg gaagagtcta ccgaccctgt 540 tggcaagtct gatacctgtt ggtccacatc atcttttcag aagaaaataa aagcatttaa 600 ttgccaatgg gaggagaagc ccatactgct actataactt gtgtatgtta aatgtctgtt 660 ttaaaagaaa gtagtgttaa atgtatcagt aactgaaatg atatgctttc tctgtgcatt 720 aaatttgtga aaattctgca t 741 <210> 191 <211> 1185 <212> DNA <213> HUMAN <400> 191 gctcagggca catgcctccc ctccccaggc cgcggcccag ctgaccctcg gggctccccc 60 ggcagcggac agggaagggt taaaggcccc cggctccctg ccccctgccc tggggaaccc 120 ctggccctgt ggggacatga actgtgtttg ccgcctggtc ctggtcgtgc tgagcctgtg 180 gccagataca gctgtcgccc ctgggccacc acctggcccc cctcgagttt ccccagaccc 240 tcgggccgag ctggacagca ccgtgctcct gacccgctct ctcctggcgg acacgcggca 300 gctggctgca cagctgaggg acaaattccc agctgacggg gaccacaacc tggattccct 360 gcccaccctg gccatgagtg cgggggcact gggagctcta cagctcccag gtgtgctgac 420 aaggctgcga gcggacctac tgtcctacct gcggcacgtg cagtggctgc gccgggcagg 480 tggctcttcc ctgaagaccc tggagcccga gctgggcacc ctgcaggccc gactggaccg 540 gctgctgcgc cggctgcagc tcctgatgtc ccgcctggcc ctgccccagc cacccccgga 600 cccgccggcg cccccgctgg cgcccccctc ctcagcctgg gggggcatca gggccgccca 660 cgccatcctg ggggggctgc acctgacact tgactgggcc gtgaggggac tgctgctgct 720 gaagactcgg ctgtgacccg gggcccaaag ccaccaccgt ccttccaaag ccagatctta 780 tttatttatt tatttcagta ctgggggcga aacagccagg tgatcccccc gccattatct 840 ccccctagtt agagacagtc cttccgtgag gcctggggga catctgtgcc ttatttatac 900 ttatttattt caggagcagg ggtgggaggc aggtggactc ctgggtcccc gaggaggagg 960 ggactggggt cccggattct tgggtctcca agaagtctgt ccacagactt ctgccctggc 1020 tcttccccat ctaggcctgg gcaggaacat atattattta tttaagcaat tacttttcat 1080 gttggggtgg ggacggaggg gaaagggaag cctgggtttt tgtacaaaaa tgtgagaaac 1140 ctttgtgaga cagagaacag ggaattaaat gtgtcataca tatcc 1185 <210> 192 <211> 1206 <212> DNA <213> HUMAN <400> 192 gaattcccgc cattgccgcc atcgtcgtgg ggcttctggg gcagctaggg ctggccgcgc 60 tgcctgcgcc ggaccggggc gggtccagtc ccgggcgggc cgtcgcggga gagaaataac 120 atctgctttg ctgccgagct cagaggagac cccagacccc tcccgcagcc agagggctgg 180 agcctgctca gaggtgcttt gaagatgccg gaggccccgc ctctgctgtt ggcagctgtg 240 ttgctgggcc tggtgctgct ggtggtgctg ctgctgcttc tgaggcactg gggctggggc 300 ctgtcgctta tcggctggaa cgagttcatc ctgcagccca tccacaacct gctcatgggt 360 gacaccaagg agcagcgcat cctgaaccat gtgctgcagc atgcggagcc cgggaacgca 420 cagagcgtgc tggaggccat tgacacctac tgcgagcaga aggagtgggc catgaacgtg 480 ggcgacaaga aaggcaagat cgtggacgcc gtgattcagg agcaccagcc ctccgtgctg 540 ctggagctgg gggcctactg tggctactca gctgtgcgca tggcccgcct gctgtcacca 600 ggggcgaggc tcatcaccat cgagatcaac cccgactgtg ccgccatcac ccagcggatg 660 gtggatttcg ctggcatgaa ggacaaggtc acccttgtgg ttggagcgtc ccaggacatc 720 atcccccagc tgaagaagaa gtatgatgtg gacacactgg acatggtctt cctcgaccac 780 tggaaggacc ggtacctgcc ggacacgctt ctcttggagg aatgtggcct gctgcggaag 840 gggacagtgc tactggctga caacgtgatc tgcccaggtg cgccagactt cctagcacac 900 gtgcgcggga gcagctgctt tgagtgcaca cactaccaat cgttcctgga atacagggag 960 gtggtggacg gcctggagaa ggccatctac aagggcccag gcagcgaagc agggccctga 1020 ctgccccccc cggcccccct ctcgggctct ctcacccagc ctggtactga aggtgccaga 1080 cgtgctcctg ctgaccttct gcggctccgg gctgtgtcct aaatgcaaag cacacctcgc 1140 cgagcctgcg ccctgacatg ctaacctctc tgaactgcaa cactggattg ttctttttta 1200 agactc 1206 <210> 193 <211> 4426 <212> DNA <213> HUMAN <400> 193 tgccttgacc aggacttggg actttgcgaa aggatcgcgg ggcccggaga ggtgttggag 60 agcacaatgg ctgaacaagt ccttcctcag gctttgtatt tgagcaatat gcggaaagct 120 gtgaagatac gggagagaac tccagaagac atttttaaac ctactaatgg gatcattcat 180 cattttaaaa ccatgcaccg atacacactg gaaatgttca gaacttgcca gttttgtcct 240 cagtttcggg agatcatcca caaagccctc atcgacagaa acatccaggc caccctggaa 300 agccagaaga aactcaactg gtgtcgagaa gtccggaagc ttgtggcgct gaaaacgaac 360 ggtgacggca attgcctcat gcatgccact tctcagtaca tgtggggcgt tcaggacaca 420 gacttggtac tgaggaaggc gctgttcagc acgctcaagg aaacagacac acgcaacttt 480 aaattccgct ggcaactgga gtctctcaaa tctcaggaat ttgttgaaac ggggctttgc 540 tatgatactc ggaactggaa tgatgaatgg gacaatctta tcaaaatggc ttccacagac 600 acacccatgg cccgaagtgg acttcagtac aactcactgg aagaaataca catatttgtc 660 ctttgcaaca tcctcagaag gccaatcatt gtcatttcag acaaaatgct aagaagtttg 720 gaatcaggtt ccaatttcgc ccctttgaaa gtgggtggaa tttacttgcc tctccactgg 780 cctgcccagg aatgctacag ataccccatt gttctcggct atgacagcca tcattttgta 840 cccttggtga ccctgaagga cagtgggcct gaaatccgag ctgttccact tgttaacaga 900 gaccggggaa gatttgaaga cttaaaagtt cactttttga cagatcctga aaatgagatg 960 aaggagaagc tcttaaaaga gtacttaatg gtgatagaaa tccccgtcca aggctgggac 1020 catggcacaa ctcatctcat caatgccgca aagttggatg aagctaactt accaaaagaa 1080 atcaatctgg tagatgatta ctttgaactt gttcagcatg agtacaagaa atggcaggaa 1140 aacagcgagc aggggaggag agaggggcac gcccagaatc ccatggaacc ttccgtgccc 1200 cagctttctc tcatggatgt aaaatgtgaa acgcccaact gccccttctt catgtctgtg 1260 aacacccagc ctttatgcca tgagtgctca gagaggcggc aaaagaatca aaacaaactc 1320 ccaaagctga actccaagcc gggccctgag gggctccctg gcatggcgct cggggcctct 1380 cggggagaag cctatgagcc cttggcgtgg aaccctgagg agtccactgg ggggcctcat 1440 tcggccccac cgacagcacc cagccctttt ctgttcagtg agaccactgc catgaagtgc 1500 aggagccccg gctgcccctt cacactgaat gtgcagcaca acggattttg tgaacgttgc 1560 cacaacgccc ggcaacttca cgccagccac gccccagacc acacaaggca cttggatccc 1620 gggaagtgcc aagcctgcct ccaggatgtt accaggacat ttaatgggat ctgcagtact 1680 tgcttcaaaa ggactacagc agaggcctcc tccagcctca gcaccagcct ccctccttcc 1740 tgtcaccagc gttccaagtc agatccctcg cggctcgtcc ggagcccctc cccgcattct 1800 tgccacagag ctggaaacga cgcccctgct ggctgcctgt ctcaagctgc acggactcct 1860 ggggacagga cggggacgag caagtgcaga aaagccggct gcgtgtattt tgggactcca 1920 gaaaacaagg gcttttgcac actgtgtttc atcgagtaca gagaaaacaa acattttgct 1980 gctgcctcag ggaaagtcag tcccacagcg tccaggttcc agaacaccat tccgtgcctg 2040 gggagggaat gcggcaccct tggaagcacc atgtttgaag gatactgcca gaagtgtttc 2100 attgaagctc agaatcagag atttcatgag gccaaaagga cagaagagca actgagatcg 2160 agccagcgca gagatgtgcc tcgaaccaca caaagcacct caaggcccaa gtgcgcccgg 2220 gcctcctgca agaacatcct ggcctgccgc agcgaggagc tctgcatgga gtgtcagcat 2280 cccaaccaga ggatgggccc tggggcccac cggggtgagc ctgcccccga agaccccccc 2340 aagcagcgtt gccgggcccc cgcctgtgat cattttggca atgccaagtg caacggctac 2400 tgcaacgaat gctttcagtt caagcagatg tatggctaac cggaaacagg tgggtcacct 2460 cctgcaagaa gtggggcctc gagctgtcag tcatcatggt gctatcctct gaacccctca 2520 gctgccactg caacagtggg cttaagggtg tctgagcagg agaggaaaga taagctcttc 2580 gtggtgccca cgatgctcag gtttggtaac ccgggagtgt tcccaggtgg ccttagaaag 2640 caaagcttgt aactggcaag ggatgatgtc agattcagcc caaggttcct cctctcctac 2700 caagcaggag gccaggaact tctttggact tggaaggtgt gcggggactg gccgaggccc 2760 ctgcaccctg cgcatcagga ctgcttcatc gtcttggctg agaaagggaa aagacacaca 2820 agtcgcgtgg gttggagaag ccagagccat tccacctccc ctcccccagc atctctcaga 2880 gatgtgaagc cagatcctca tggcagcgag gccctctgca agaagctcaa ggaagctcag 2940 ggaaaatgga cgtattcaga gagtgtttgt agttcatggt ttttccctac ctgcccggtt 3000 cctttcctga ggacccggca gaaatgcaga accatccatg gactgtgatt ctgaggctgc 3060 tgagactgaa catgttcaca ttgacagaaa aacaagctgc tctttataat atgcaccttt 3120 taaaaaatta gaatatttta ctgggaagac gtgtaactct ttgggttatt actgtcttta 3180 cttctaaaga agttagcttg aactgaggag taaaagtgtg tacatatata atataccctt 3240 acattatgta tgagggattt ttttaaatta tattgaaatg ctgccctaga agtacaatag 3300 gaaggctaaa taataataac ctgttttctg gttgttgttg gggcatgagc ttgtgtatac 3360 actgcttgca taaactcaac cagctgcctt tttaaaggga gctctagtcc tttttgtgta 3420 attcacttta tttattttat tacaaacttc aagattattt aagtgaagat atttcttcag 3480 ctctggggaa aatgccacag tgttctcctg agagaacatc cttgctttga gtcaggctgt 3540 gggcaagttc ctgaccacag ggagtaaatt ggcctctttg atacactttt gcttgcctcc 3600 ccaggaaaga aggaattgca tccaaggtat acatacatat tcatcgatgt ttcgtgcttc 3660 tccttatgaa actccagcta tgtaataaaa aactatactc tgtgttctgt taatgcctct 3720 gagtgtccta cctccttgga gatgagatag ggaaggagca gggatgagac tggcaatggt 3780 cacagggaaa gatgtggcct tttgtgatgg ttttattttc tgttaacact gtgtcctggg 3840 ggggctggga agtcccctgc atcccatggt accctggtat tgggacagca aaagccagta 3900 accatgagta tgaggaaatc tctttctgtt gctggcttac agtttctctg tgtgctttgt 3960 ggttgctgtc atatttgctc tagaagaaaa aaaaaaaagg aggggaaatg cattttcccc 4020 agagataaag gctgccattt tgggggtctg tacttatggc ctgaaaatat ttgtgatcca 4080 taactctaca cagcctttac tcatactatt aggcacactt tccccttaga gccccctaag 4140 tttttcccag acgaatcttt ataatttcct ttccaaagat accaaataaa cttcagtgtt 4200 ttcatctaat tctcttaaag ttgatatctt aatattttgt gttgatcatt atttccattc 4260 ttaatgtgaa aaaaagtaat tatttatact tattataaaa agtatttgaa atttgcacat 4320 ttaattgtcc ctaatagaaa gccacctatt ctttgttgga tttcttcaag tttttctaaa 4380 taaatgtaac ttttcacaag agtcaacatt aaaaaataaa ttattt 4426 <210> 194 <211> 1810 <212> DNA <213> HUMAN <400> 194 ggggggaagg ccaagcagtg accaggaaga gggagaaact tctgctcaga ccgagcgtgt 60 gccactggac ctcagtcctc gcctggagga gacgctggac ttcggcgagg tggaagtgga 120 gcccagtgag gtggaagact tcgaggctcg tgggagccgc ttctccaagt ctgctgatga 180 gagacagcgc atgctggtcg cagcgtaagg acgaactcct ccagcaagct cgcaaacgtt 240 tcttgaacaa aagttctgaa gatgatgcgg cctcagagag cttcctcccc tcggaaggtg 300 cgtcctctga ccccgtgacc ctgcgtcgaa ggatgctggc tgccgcgcgg aacggaggct 360 tcagaagcag cagacctcct agcgctccct tgccttcctc agctgcctcc tgcgccctgt 420 gcccgactga ctggaggagg cctgtcccaa ttctgccgct ccatggaaaa gcgggcttga 480 ctgcattgcc gctgtataaa gcatgtggtc ttatagtgtt tggacagctg ataaatttaa 540 tccttctttg taatactttc tatgtgacat ttctcttccc cttagaaaca ctgcaaattt 600 taactgtagg tatgatctct tctggtgttg actggactgc ttggggtggg ggacgatcag 660 gaggaagtga gccagtcgcc tgcctgcagc aggcagcttc tactcctgcc tcatgcatac 720 gtcccacaaa tgcaggtgtc ctgagcacca cacccagtgg gaagagtgtg ggggaggcgc 780 acagtgtgag cccgccccca cgtcgtgggg taacatctgt tatcaaactg ctgtcgttgt 840 tgtggaagca tgtagactgt gccagagcca gacccacggg ctcatgcacc cctgagcagc 900 agggcatctt ggaaaaggaa ctcttggttc gatacctgga gcagaggagg ggaaagtcca 960 gggctatagg gtgtgatgaa gtcacccctt tctgtcccac tacatctggg actgactttc 1020 cgagcctcca gtccaaagcc ggcttgattt ccgtgaactc tggtgctcct gcatctcatg 1080 agtgtgcccc atgggtcccc tcccctctca gcatttcctt gtcccgtctg gacctgggga 1140 gtggttaggc agcaagcttt ggtttatggt tttcattcat tggtgaagta aattaggcag 1200 tgctaaagcc tgtgggtttg gtccttgaac aagatgtggg ccttgcaaga tgggagagta 1260 aaccttgaag ggctttatta aagaaataaa aaagaacttt tgtatctttt atcctgggag 1320 cactgcgttt tcctagctgt gttattcctg gtttaattca gcagagaagg taaggtgtga 1380 acctacctgc cttggagagg cccaggtccc aaatctcttc aaattcttca catgtttaac 1440 tttaaggatt tgaaccatga agtcataggt tacagacctc agttttatgc cccattggat 1500 tacttttttt tttttttttt tttttttact ctttgaaagc tttgttttgt ggtagtcgct 1560 tttgggaaga atccagtatt atctacaatt attggcaaag tttaaatgta ttttacataa 1620 cggaaagttt ttagaatgtt gaaaagtaat tgaaaaaggt gataggtaaa tttttaggca 1680 aagataattt atttcaataa atctttcaaa agccttacct tgaaatgctg ttagtaaatt 1740 tctgtgcatt tttttttttt aatttgtttt gctgagagca tagctatttg tttttattgt 1800 aaacccgccc 1810 <210> 195 <211> 393 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(393) <223> N=any base <400> 195 gcgaccgctc tcctacccgg acaccgacgt cattctcatg tgcttctcgg tggacagccc 60 ggactcgctg gagaacatcc ccgagaagtg ggtccccgag gtgaagcact tctgtcccaa 120 tgtgcccatc atcctggtgg ccaacaanaa agacctgcgc aggacgagca tgtccgcaca 180 gagctggccc gcatgaagca ggaacccgtg cgcacggatg acggccgcgc atggccgtgc 240 gcatccaagc ctacgactac ctcgagtgct ctgccaagac caaggaaggc gtgcgcgagg 300 tcttcgagac ggccacgcgc gccgnntgca agaaagcgtt acggctccca gaacggctgc 360 atcaactgct gcaaggtgct atgagggccg cgc 393 <210> 196 <211> 477 <212> DNA <213> HUMAN <400> 196 ttttcatagc agcttcttgt ccagctttat tgggaggcca gcttgcctgg aggggggcca 60 ggcatgaggt ggggtaggag agcactgaga atactgtccc ttttaagcaa cctacagggg 120 aagccctgga gattgcagga cccaaggagc tggcaggatg gataggcagg tggacttggg 180 gtattgaggt ctcaggcagc cacggctgaa agttggtctg acctcagggt ccaaatccca 240 gaactcagag aacttgtcct taacggtgct ccagtagtct ttcagggaac tgaagccatc 300 ggtcacccag cccctggctg cttgggcacc tgggactcct gcacgctgct cagtgcatcc 360 ttggcggtct tggtggcgtg cttcatgtag ccctgcatga agctgagaag ggaggcatcc 420 tcggcctctg aagctcgggc agaggcagga gcgccaggag ggcaacaaca aggagta 477 <210> 197 <211> 477 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(477) <223> N=any base <400> 197 tttttttcgc attcaactta aatgctttta ttgacaatgt cttggaacaa taagcaaaca 60 atgcttaaat ttttcattca aattcacttt ccacatgtca aaagacctca aggtagaaaa 120 aaataaaata aaaatataaa tatctgagaa tccatcttaa taaataaatt aaaaacacaa 180 taaaacgttt tcatggaaaa ctgttaatgt cagaacattc agaccacctc aacaatgcat 240 gatcagtaac attacaatga acattgatgt tgaagaaaaa ctacagtaca tggatatagc 300 tatttatttc tatctaccag aaaataaagt cgtatctttt cttagtataa tattgggtca 360 tttctaatca gaacacacta ttgccaggaa cacagtagtt attgttaaaa tcagccgcac 420 tagataccat ttggaaatat ccagcaccag gttaattccc ataatgnacc ccatagg 477 <210> 198 <211> 471 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(471) <223> N=any base <400> 198 nttttttcag ttacactttt ccttgcttta atatttgttg tctttttctg cttttgaaat 60 gagctctcaa ttacaaaata ccaaactaca ctcaaaagag ggtgtagaaa aagccagcca 120 ttggaccagc atggagaagc ccacaagtaa ggacagatag cagcagcagg tggcaagagg 180 tgggaggtga ctgaagcagt ggttacaaat gttcacagga agctaaaact atccaacagg 240 ttgtgcccta atgttagcac aggttagact agttactacc ttgctaggtg gcctcagtgt 300 gttcagattc tacgcagcaa tacaatttct tccagttaag agttcttgac ttgcaccgat 360 cacagcatgg ttgaagggta ctgggaccag tcttgttagt ttttcaaaat gctgtcgtag 420 anctggatag atgtattgag agacttcagg agctctacac ttcagtgaca g 471 <210> 199 <211> 249 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(249) <223> N=any base <400> 199 agcacattca atccaatttg gacttctctc cagtaaacag tgcttctagt gaagaaaatg 60 tgaagtactc cagttctcag ccagaacccc gcacaggtct ttccttatgg gataccagcc 120 cctcatacat tgataaattg gtacaaggga tcagcttttc ccagcccaca tgtcctgatc 180 atatgctttt gaatagtcag ttacttggca ccccaggatc ctcacagaan cctgggacnc 240 ggtgttggt 249 <210> 200 <211> 357 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(357) <223> N=any base <400> 200 ctctccttgg aggaccttta ggtaaactcc ctagtctcca cctgagaccc tgggagagaa 60 gtttgaagca caactccctt aaggtctcca aaccagaccg gtgacgcctg cgggaccatc 120 tggggcacct gcttccaccc gtctctctgc ccactcgggt ctgcagaact ggtttccaat 180 tgaggccctt tgcaggatgg aantacgggg cttacaggag cttttgtgtg cctggtagaa 240 actatttctg ttccagtcac attgccatca ctcttgtact gcctgccacc gcggaggagg 300 ctggtgacag gccaaagnag gttggaagaa acatcctttc atctcagagt ccactgt 357 <210> 201 <211> 495 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(495) <223> N=any base <400> 201 gcgtggtgac catcatcaag gggaaggtgg aggaggtgga gctcccagtg gagaaggtgg 60 acatcatcat cagcgagtgg atgggctact gctcttctac gagtccatgc tcaacaccgt 120 gctctatgcc cgggacaagt ggctggcgcc gatggcctca tcttcccaga ccgggccacg 180 ctgtatgtga cggccatcga ggaccggcag tacaaagact acaagatcca ctggtgggag 240 aacgtgtatg gcttcgacat gtcttgcatc aaagatgtgg ccattaagga gcccctagtg 300 gatgtcgtgg accccaaaca gctggtcacc aacgccttgc cttcataaag gaggttggac 360 atctataccg tcaaggtgga agaccttgac ctttcanctc ccccgtttct gngccttgca 420 agttgaancc ggaattgact tacgtgcacg gccctggtgg gctactttca acatcgaggt 480 tnacacgctg gcaaa 495 <210> 202 <211> 398 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(398) <223> N=any base <400> 202 gtgtaaaatt gttaaccttg taagatggat aatgtgtata agaatgtagg ccttaactat 60 ttcacatgag tcaaaacaaa gcagctttaa aaaaataatt ggaagcacaa gtgcatggcn 120 tgactgaatg ctgttaatat ttctaaaagt ttccacantc cagntaatat ggcctgattc 180 atagtaaaat acctctaata aacactgttt tatagaaaac ctgacttcag tgaatatttt 240 tgtattttac atgggccagt ttatatactg ctactttaca ctattatttc ctatagctac 300 atgttctttg taccttttgt agttttattt gtattactag attcatacct tgatggtaac 360 gctctatctg gttttgggtg tttttcatgt tttagcat 398 <210> 203 <211> 426 <212> DNA <213> HUMAN <400> 203 ttattttcaa gattacattt aagctctaga atctcattcc ctttttctct tccaagagcc 60 agaagttcat cagttttggt tttcaactct gtattcagcc atgtattctg actatgtagc 120 aattcctttt cttgctccaa gcgtttttct cgatacttaa cagaaacatc agaagcttga 180 agttcatcca attttaactg aagttcaccc tttgttgtat tgctttcttt aagtttttca 240 ttcagacgtt taacatcctc tgttaagtat tcaagttctt gagatagtct ctcattgggt 300 tctaattaag tctcttttct cagcttctaa ttcttccttt gttcttgtaa attggctctg 360 aatgggcaat attgcgatcc tgaggcaatt tcaagttctt tgtttttctc aggtaggggc 420 cttcag 426 <210> 204 <211> 328 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(328) <223> N=any base <400> 204 aagtcttcct aaattttatt ggcactgaaa tagaacatgg attgagcata aaccactcca 60 aaaacaattt tttaaaaaac ccaaaaagta cacaaaaaac ccctgantac aaaatctaac 120 cttttccccc agcctcccta agggtaagtt actgacttta aggcagctat taatagattg 180 ccccacaatt ccagggnttc aatttaggcc aatataggga catatcacca agtgaggcta 240 attcacaggc aatgcacaca agactcctca agggcanggc cagagtgggg gggttgttgg 300 cngggggggg atttgggggn gggtttta 328 <210> 205 <211> 302 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(302) <223> N=any base <400> 205 gtaccntgat caagtttatt gcatgccttt cttttcctat ttcttttttt aagggttagt 60 attaacaaat ggcaatgagt agaaaagtta acatgaagat tttagaagga gagaacttac 120 aggacacaga tttgtgattc tttgactgtg acactattgg atgtgattct aaaagctttt 180 attgagcatt gtcaaatttg taagcttcat aggggatggg ncatccatat ctataatgcc 240 ccttcctata tggtgcctac ccataggatg tggccatttt ttgnccctta atatccggnc 300 tt 302 <210> 206 <211> 229 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(229) <223> N=any base <400> 206 tttttttttt tttttttttt tttaccaggg ggngaaacaa ttttatttca canttgtctt 60 taaaaccaca agacacctat gttcttcana taaaaacatt agtatagata cccatacttt 120 ctagaaaatg attatacaga ccctttcaaa gaaaaatgta ttccattata taggnttcag 180 tgaggttgct tggggaaaaa ctcacatctg gggctgattc ctaaaacat 229 <210> 207 <211> 448 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(448) <223> N=any base <400> 207 ggatctggtc tcccacaatg aaggtcttgc ctccctggtt ctgggacagc agggtctcaa 60 aaggcttcag ttgcccgggc agtgcttcac atagtcatcc ttgcccgcct catagttggt 120 gtagatgagg gagatgtatt tgcagcggag gtcctccacg ccgtcattca ccatgtccac 180 cagggctgcc tcctgctggt ccttcccata gagcccaagg gtgcgggccc agggtgacgc 240 aggatggtat tggactggta cagggtgagg tctccgtcct gggaacttng gggagctgcc 300 cgtattaggc anggaggctt ttgagttgag ccctccttnc ggccgcaagc ttatttccct 360 tttagttgag ggttaanttt aagtttggca attggccttc tttttaaaaa cttcgtgatt 420 tgggaaaanc tgggntttaa ccaattta 448 <210> 208 <211> 488 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(488) <223> N=any base <400> 208 tttttttttg tgtgcaagtg tttatttgga atcccttcta ttttattaga aacagaaaca 60 gtaatttcac cagtaggaat tgcgtgtgct ctcaatacaa gtaagtttgc cactccttca 120 attgttgtcc attgcagaca ctttggattc aaggttaaga atccaaatga gaaataagaa 180 atatccggtc cctgatgatt cgtttaagtc ctgttcaact cgatggaaag cttccacccg 240 aaggaaggag ttactgttcc tcctgggctg ggctttgtgt ttctttcagt gctctaaagg 300 aactttgtat ttggggcagc tgtgctctgg tcatgtcagg gctggctggg acagggagtt 360 tggatggctt acgggcggcc gctggaccgg gggctggctt tttacttgaa ggcttcactg 420 ggggtgttcc attcaattca caaagtgggg cgttntgcag gccngtggaa gggttttgcn 480 gggggntt 488 <210> 209 <211> 353 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(353) <223> N=any base <400> 209 tttttttttt gctttttata ccactttatt ccaacctgag cacctcaata taaaactaaa 60 cactggtgaa ccgttttcct aattctgcat tatcataaat gtacaagttc tcctagcagt 120 ccaacactta aatagattaa atcatctctg acacatggta gctttcatat aatgaaaata 180 cctaaaataa ttagttgcaa tatactgnaa ctggatcaaa ataaaatgga actttgggna 240 agggngggct ggcaggattg ttacttaaca tattggcaat actttatggt tacaanttcg 300 ggggnccatt gntttatttt ggggttctgg ccctgggggg ggccacctgt agg 353 <210> 210 <211> 487 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(487) <223> N=any base <400> 210 ggacagaatt tcatnattat tggataaata catgcaggca ctgtgcttgg cctggggctc 60 caagttagca gacgtggttc ccaccttgag ctcagtcttt ctgtgggggc cactgcacag 120 gcgtgatggg tcctgggaga gggtntggag ctagggcagg gcagagctgn agaagacagc 180 ctccaagggt ggggatntca cgggcccgtg cccctntttt atttttattt tttccttgag 240 acggagntcg nctgtgttgc ccaggctgga gtgcaatggc gcaatcttgg ctcactgcaa 300 cctccacctc ccaggttcaa gcaattctcc tacctcaacc tcctgagtag ctggggacta 360 cagggtntgt gccaccacgc ctgggatttt gtatttttag tagagatggg gttttcgcca 420 gggtggnctt ttaactcccg accccanggg atccaccctn cttgggctcc caaagtgttg 480 ggattaa 487 <210> 211 <211> 384 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(384) <223> N=any base <400> 211 caagagtaga ttctnttntt catttctctt ttttttctta aaaaaaaaag tattcatttg 60 gtataaaaaa taaatatttt aaatatgaca ttgantaaat aaaaataatc tgtcagtatg 120 aaacatcccc acagggtaca ttcatcaaag aggattttgt cacccaaggc catgtgcttt 180 tcagtggaag ggaaggaggg aaacctctaa ggccgcacgg tgggcccacg gagctagcac 240 gtgggcgggg actganggct ggatgcccgg nttgagggtg gggaactaga gatgactnta 300 agggcaggga acatctgtac cntctgcagg gaaattgcta ccctccccgg gtgccngagg 360 ttccacccca caaantttgt ctac 384 <210> 212 <211> 409 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(409) <223> N=any base <400> 212 gggtaggaaa ggtccccaga agcatggggg ctgagtcagt cagcaaatgc ataaggccta 60 ggcacagagg agcaggttag ggcacattca ccttntcagg attctgtggc tccctcattg 120 gagaagggag agagcatctt gggggcgcaa ttccaagagc agcgagggca gaggttagag 180 atggctgaga gcccctaacc tgaggcggca ccacantagg cagcaacaac tntntggaaa 240 gctggatgaa ctggtcagta gcggaaantg ggagggggca ctgggttggc ctnttgggga 300 ggggtccaac cttggcttgg atgagctcat gagantaccc agttttccca agcagagggg 360 ggcagagcaa aagccctttt tntgcaggcc tcctttaagg agaaaaagg 409 <210> 213 <211> 289 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(289) <223> N=any base <400> 213 ttaacaggag acaggggttt tattattact caaatcagcc tccctgaaaa tttggaggct 60 agggtttttt aaaggtagtt tggcgggcag gggttggagg tagagcaatg tcatttagct 120 tgctcacttc catctgccag tttggnagct tcttggctga nagatggcgc cgggcatgct 180 tggtcaaatg gtcactcctc atgaaccgcc ggtcacacat ggggcacgca aatttcttct 240 cacccgtgtg ggttcgcctg tgtctggaca gttcancaga acgggcaaa 289 <210> 214 <211> 399 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(399) <223> N=any base <400> 214 nnnnnaggga aaaaaaatgg aaaatttatt aattagacag tatgtgggca tcctgtncca 60 catgggaatg agaagatgct ataggtnctc taagtattgc acagtctgaa aaaataacaa 120 aaaaagggaa ggggaggaaa aaaaaatcac atgatattgg ganccatctc acattatgan 180 tantctacca agaaacattt aaaaaagaaa nccctttgtt tctacagtag gctttaagtt 240 tatagttctt gggantgact gtattccatt gaaggacatc tcaggtaaca gggaaggctg 300 ttttaggcaa tccccatgtg gcaaatatta ataaaanata tatanttttt tgccaattca 360 tctctngcct tcaccccggg caatcatgac atttncgag 399 <210> 215 <211> 447 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(447) <223> N=any base <400> 215 acctcagtct gacgacattg aagctagccg aatgaagcga gcagctgcaa agattctaat 60 agaacgctac taccaccagt taactgaggg ctgtggaaat gaagcctgca cgaatgagtt 120 ttgtgcttcc tgtccaactt ttcttcgtat ggataataat gcagcagcta ttaaagccct 180 cgagctttat aagattaatg caaaactctg tgatcctcat ccctccaaga aaggagcaag 240 ctcagcttac cttgagaact cgaaagggtg cccccaacaa ctcctgctct gaggataaaa 300 atgaacaaga aaggcgctag aattgatttt aaagatgtga cttactttaa cagaagngaa 360 gggtatatgg aaattcttga attatgtagg aggaaagaga gggttatttc ccctntaatc 420 cctgttcttt gggaggagtt ttttcta 447 <210> 216 <211> 1460 <212> DNA <213> HUMAN <400> 216 gcacacggga agatatcaga aacatcctag gatcaggaca ccccagatct tctcaactgg 60 aaccacgaag gctgtttctt ccacacagca ctttgatctc catttaagca ggcacctctg 120 tcctgcgttc cggagctgcg ttcccgatgg tcctcctttg gctcacgctg ctcctgatcg 180 ccctgccctg tctcctgcaa acgaaggaag atccaaaccc accaatcacg aacctaagga 240 tgaaagcaaa ggctcagcag ttgacctggg accttaacag aaatgtgacc gatatcgagt 300 gtgttaaaga tgccgactat tctatgccgg cagtgaacaa tagctattgc cagtttggag 360 caatttcctt atgtgaagtg accaactaca ccgtccgagt ggccaaccca ccattctcca 420 cgtggatcct cttccctgag aacagtggga agccttgggc aggtgcggag aatctgacct 480 gctggattca tgacgtggat ttcttgagct gcagctgggc ggtaggcccg ggggcccccg 540 cggacgtcca gtacgacctg tacttgaacg ttgccaacag gcgtcaacag tacgagtgtc 600 ttcactacaa aacggatgct cagggaacac gtatcgggtg tcgtttcgat gacatctctc 660 gactctccag cggttctcaa agttcccaca tcctggtgcg gggcaggagc gcagccttcg 720 gtatcccctg cacagataag tttgtcgtct tttcacagat tgagatatta actccaccca 780 acatgactgc aaagtgtaat aagacacatt cctttatgca ctggaaaatg agaagtcatt 840 tcaatcgcaa atttcgctat gagcttcaga tacaaaagag aatgcagcct gtaatcacag 900 aacaggtcag agacagaacc tccttccagc tactcaatcc tggaacgtac acagtacaaa 960 taagagcccg ggaaagagtg tatgaattct tgagcgcctg gagcaccccc cagcgcttcg 1020 agtgcgacca ggaggagggc gcaaacacac gtgcctggcg gacgtcgctg ctgatcgcgc 1080 tggggacgct gctggccctg gtctgtgtct tcgtgatctg cagaaggtat ctggtgatgc 1140 agagactctt tccccgcatc cctcacatga aagaccccat cggtgacagc ttccaaaacg 1200 acaagctggt ggtctgggag gcgggcaaag ccggcctgga ggagtgtctg gtgactgaag 1260 tacaggtcgt gcagaaaact tgagactggg gttcagggct tgtgggggtc tgcctcaatc 1320 tccctggccg ggccaggcgc ctgcacagac tggctgctgg acctgcgcac gcagcccagg 1380 aatggacatt cctaacgggt ggtgggcatg ggagatgcct gtgtaatttc gtccgaagct 1440 gccaggaaga agaacagaac 1460 <210> 217 <211> 349 <212> DNA <213> HUMAN <400> 217 atctgttgtc agcacagttt tatttgctgt ggaatccatg agagccggaa gcatcgttgg 60 ggccgtggct agcagagctc atggtgacca gtcctgggcc tgaccaatgg gtgattacat 120 ttaaaaacca aaacaaaaca aaacaaaata ccaagaacag atcacttgcc atggacatca 180 gtaatctatt ggtaatggtg aaaatttcat gaaaatttcc cctaaaccat aacaaaaact 240 gtcctcctta ccccaaaagt gctggaggga aagatggttg catggctttg acctctcttt 300 gaacttgaaa tgctaccttc ctacccggaa aatgcggcac actatactt 349 <210> 218 <211> 1882 <212> DNA <213> HUMAN <400> 218 tggcatcctg gtcctctcac atggctcctt aaaattggct gtggcttgtt ttttgtgatg 60 tttgcttggt tgcctgttcc cttttctacc tgcagagcac ggttcccata agggcggcga 120 gatcagcctc ctgtctcatc tggaagacca ccactctggg gtctcagagg aatgatggaa 180 gccttggggt ttctaaaatt ggaagtgaat ggccccatgg tgacggtggc cctgtcagtg 240 gctctcttgg ccctcctgaa atggtactcc acatcagcat tctcaagact ggagaagtta 300 ggcctcagac atcccaagcc ttctcctttc attggaaact tgacattttt ccgccagggt 360 ttttgggaaa gccaaatgga gctcagaaag ctgtatggac ctctgtgtgg gtactatctt 420 ggtcgtcgga tgtttattgt tatttctgag ccagacatga tcaagcaggt gttggttgag 480 aacttcagta actttaccaa cagaatggcg tcgggtttgg agttcaagtc ggtagccgac 540 agcgttctgt ttttacgtga caaaagatgg gaagaggtca gaggtgccct gatgtctgct 600 ttcagtcctg aaaagctgaa cgagatggtt cccctcatca gccaagcctg cgaccttctc 660 ctggctcatt taaaacgcta tgcggaatct ggggacgcat ttgacatcca gaggtgctac 720 tgcaattaca ccacagatgt ggttgccagc gtcccgtttg gcaccccggt ggactcctgg 780 caggcccctg aggatccctt tgtgaaacac tgcaagcgtt tcttcgaatt ctgcatcccc 840 agacctatcc tggttttact cttatcattt ccatccataa tggtcccact ggcccggatt 900 ttgcccaata agaaccgaga cgaactgaat ggctttttta acaaactcat taggaatgtg 960 attgccttgc gggaccagca agctgccgaa gagaggcgga gagacttcct ccaaatggtc 1020 ctggatgccc gacattctgc aagtcccatg ggcgtgcaag actttgacat cgtcagagac 1080 gttttctcct ctactgggtg caagccgaac ccttcccggc aacaccagcc cagccctatg 1140 gccaggcctt tgactgtgga tgagattgtg ggccaggcct tcatcttcct catcgctggc 1200 tatgaaatca tcaccaacac actttctttt gccacctacc tactggccac caaccctgac 1260 tgccaagaga agcttctgag agaggtagac gtttttaagg agaaacacat ggcccctgag 1320 ttctgcagcc tcgaggaagg cctgccctat ctggacatgg tgattgcaga gacgctgagg 1380 atgtacccgc cagctttcag attcacacgg gaggcagctc aggactgcga ggtgctgggg 1440 cagcgcatcc ccgcaggcgc tgtgctagag atggccgtgg gtgccctgca ccatgaccct 1500 gagcactggc caagcccgga gaccttcaac cctgaaaggt tcacggctga ggcccggcag 1560 cagcaccggc ccttcacgta cctgcccttc ggggccggcc cacggagctg cctcggggtg 1620 cgtctagggc tgcttgaggt caagttgaca ctgctccacg tgctgcacaa gttccggttc 1680 caagcctgcc ctgagaccca ggtaccgctg cagctagaat ccaaatctgc cctaggtcca 1740 aaaaatggtg tctatatcaa gatcgtatcc cgctgacaca gaaggctgcc gggtgggggg 1800 agggcacccc caaattcaaa gaaaacccta agtgtggatg ttcagaattt tggaaaaatg 1860 tcactgaagt gattgaaagc cg 1882 <210> 219 <211> 3397 <212> DNA <213> HUMAN <400> 219 atggcggcct tcagcaagta cttgacggcg cggaactcct cgctggctgg tgccgcgttc 60 ctgctgctct gcctgctcca caagcggcgc cgcgccctcg gcctgcacgg taagaaaagt 120 ggaaaaccac cattacagaa caatgagaaa gaggggaaaa aagagcgagc tgtggtggac 180 aaggtgtttt tctcaaggct catacagatt ctgaaaatca tggtccctag aacattttgt 240 aaagagacag gttacttggt acttattgct gttatgctgg tgtctcgaac atattgtgat 300 gtttggatga ttcaaaatgg gacactaatt gaaagtggta tcattggtcg tagcaggaaa 360 gatttcaaga gatacttact caacttcatc gctgccatgc ctcttatctc tctggttaat 420 aacttcttga agtatgggtt aaatgagctt aaactgtgct tccgagtaag gctcactaaa 480 tacctctatg aggagtatct tcaagctttc acatattata aaatggggaa tctggacaac 540 agaatagcta atccagacca gctgcttaca caagatgtag aaaaattttg taacagtgta 600 gtcgatctgt attcaaatct tagtaagcca tttttagaca tagttttgta tatctttaag 660 ttaacgagtg caattggagc tcagggccca gcgagcatga tggcctactt ggttgtttct 720 gggctattcc taactcgact tcgaagaccc attggtaaga tgacaataac tgagcaaaag 780 tatgaaggag aatatagata tgttaattct cggctcatca caaacagtga agaaattgcc 840 ttttacaatg ggaataaaag agaaaagcag acagtccact cagtcttccg aaaactggtg 900 gaacacctac ataatttcat tttgtttcgg ttttcaatgg gcttcattga tagtattatt 960 gccaaatacc ttgccactgt tgttggttac ctagttgtca gtcgcccttt cttagatttg 1020 tctcatcctc gacatctcaa gagtacacat tcggaacttc tagaggatta ctaccaaagt 1080 ggaagaatgc ttttgcgaat gtctcaagct ctgggtcgaa tagttttggc tgggcgtgaa 1140 atgactagat tggccggttt tactgctcgg attacagaat taatgcaagt actgaaggat 1200 ttaaatcatg gcaaatatga gcgcacaatg gtctcacaac aggaaaaggg tattgaagga 1260 gtacaagtca ttcccttgat acctggtgct ggagaaatca ttattgcaga taacattata 1320 aagtttgatc atgttccttt agcaacgcca aatggagatg ttttgatccg agaccttaat 1380 tttgaagttc gatctggggc taatgttcta atttgtggtc caaatggctg cggaaagagt 1440 tcacttttcc gtgttcttgg tgaattatgg cctctttttg gaggacgtct aactaaacct 1500 gaaagaggaa aattatttta tgttcctcag agaccttaca tgacccttgg aacacttcga 1560 gatcaagtga tatatccaga tggacgagaa gatcagaaaa ggaagggaat ttctgaccta 1620 gtactgaagg aatacttaga caatgtccag ttgggtcata tccttgaacg tgaaggaggc 1680 tgggacagtg ttcaggattg gatggacgta ctcagtggtg gagaaaagca aagaatggcg 1740 atggcaagat tattttatca taaaccccag tttgccattt tggatgaatg cacaagtgca 1800 gttagtgtcg acgtggaagg ctacatttat agtcattgtc gaaaggttgg catcactctc 1860 ttcactgtgt ctcataggaa atctctttgg aaacatcatg agtactacct gcatatggat 1920 ggcagaggca actatgaatt caaacagata acagaagata cagttgagtt tggctcttag 1980 agaaatctgg agaactatac ctgcttcagt gaaataatta cagaatatac ttagaaaggc 2040 aaagtacatt gtaaaataaa gttgagctta gtttttttta aaaaaaaaaa acaaagcaac 2100 aaattaacta gatacagaat aatggagaac aagttgttaa aacatttaat attatatagg 2160 atattgctaa ttgtgtatat gttggtttaa ttaataatat gtactaagaa tgtccttatt 2220 cttgtggtta aaaacctgcc taaattaaat tgggcttcaa tcactgtaac ctgattcatc 2280 ctgggatgta aaccattcga agtcagctaa ttggactttt atggctctat cttttccttc 2340 agtgaagaac cctatttaaa actgggtcat catttgtcct gttctagcaa gatagtcttc 2400 agtttcattt tcctgtgccc tgtggtagtt ggaaacaaat cataatgtat tatttaaatg 2460 tttaacatca ttgcataaca gcgtttatta tacagtggca gatttcttta gctgccacag 2520 taatactcat tccttgtgtg tgtcttggag tgcatttgac tccaggaaaa gccattttgg 2580 ttttccttaa ctaaatgata aatgtacccc tctcagtctg cagtattgag ttgtttaaag 2640 tatatgtgca gtcttgctta caaggagggg ttaccatgta tcacacctaa tcttcccaat 2700 gtttgggata ttaaaacaca aagtccttaa catgccaggc tcaaggtctt ataagagttc 2760 tagattttta agagaattag acaaatttgt gtgtgttaga agcccattca ttagaagtgt 2820 ggtggttatt tggtattaaa ctccaaatga gccataggaa ggcactacat gaaataatgc 2880 actgagtatg caatgctatc actgtctttg actgtgattt tatgtttaaa aagtatgttc 2940 taaaattatt atatatacat gggtgaatta tgtttccgag gcactgtttt atctctgtga 3000 atcttgaata acttttttat atttgggtta tgatgtcaaa cgatcctaag cgaagatgat 3060 ttcagttcat caaatcatca ttaatgactt tatgtattat ttgcacaggg agaattgaaa 3120 ctgagtataa tcaataagct agatacgaaa tcagtttctc aaactgagct tcagaaaggg 3180 gcattttgta ctcttgtttt tgcataactg gttttgtttt tttgcagaat taactataac 3240 aatcactggc taccgaagta aactgatgta ctgaattcca taatacataa cattcaattt 3300 ttaccacttc tgtttagcga acttgtatac ttattttctg ttcagattaa aaaaaaaaaa 3360 aaaaaaaact cagatatcct ataaaaaaaa aaggaat 3397 <210> 220 <211> 1543 <212> DNA <213> HUMAN <400> 220 attccaggag cctatcaacc cagataaagc gggacctcct ctctggtaga ggtgcagggg 60 gcagtactca acatgatcac agagggagcg caggcccctc gactgttgct gccgccgctg 120 ctcctgctgc tcaccctgcc agccacaggc tcagaccccg tgctctgctt cacccagtat 180 gaagaatcct ccggcaagtg caagggcctc ctggggggtg gtgtcagcgt ggaagactgc 240 tgtctcaaca ctgcctttgc ctaccagaaa cgtagtggtg ggctctgtca gccttgcagg 300 tccccacgat ggtccctgtg gtccacatgg gccccctgtt cggtgacgtg ctctgagggc 360 tcccagctgc ggtaccggcg ctgtgtgggc tggaatgggc agtgctctgg aaaggtggca 420 cctgggaccc tggagtggca gctccaggcc tgtgaggacc agcagtgctg tcctgagatg 480 ggcggctggt ctggctgggg gccctgggag ccttgctctg tcacctgctc caaagggacc 540 cggacccgca ggcgagcctg taatcaccct gctcccaagt gcgggggcca ctgcccagga 600 caggcacagg aatcagaggc ctgtgacacc cagcaggtct gccccacaca cggggcctgg 660 gccacctggg gcccctggac cccctgctca gcctcctgcc acggtggacc ccacgaacct 720 aaggagacac gaagccgcaa gtgttccgca cctgagccct cccagaaacc tcctgggaag 780 ccctgcccgg ggctagccta cgagcagcgg aggtgcaccg gcctgccacc ctgcccagtg 840 gctgggggct gggggccttg gggccctgtg agcccctgcc ctgtgacctg tggcctgggc 900 cagaccatgg aacaacggac gtgcaatcac cctgtgcccc agcatggggg ccccttctgt 960 gctggcgatg ccacccggac ccacatctgc aacacagctg tgccctgccc tgtggatggg 1020 gagtgggact cgtgggggga gtggagcccc tgtatccgac ggaacatgaa gtccatcagc 1080 tgtcaagaaa tcccgggcca gcagtcacgc gggaggacct gcaggggccg caagtttgac 1140 ggacatcgat gtgccgggca acagcaggat atccggcact gctacagcat ccagcactgc 1200 cccttgaaag gatcatggtc agagtggagt acctgggggc tgtgcatgcc cccctgtgga 1260 cctaatccta cccgtgcccg ccagcgcctc tgcacaccct tgctccccaa gtacccgccc 1320 accgtttcca tggtcgaagg tcagggcgag aagaacgtga ccttctgggg gagaccgctg 1380 ccacggtgtg aggagctaca agggcagaag ctggtggtgg aggagaaacg accatgtcta 1440 cacgtgcctg cttgcaaaga ccctgaggaa gaggaactct aacacttctc tcctccactc 1500 tgagccccct gaccttccaa acctcaataa actagcctct tcg 1543 <210> 221 <211> 1327 <212> DNA <213> HUMAN <400> 221 gccgctgtgt aggaaagaag ctaaagcact tccagagcct gtccggagct cagaggttcg 60 gaagacttat cgaccatgga gcgcgcgtcc tgcttgttgc tgctgctgct gccgctggtg 120 cacgtctctg cgaccacgcc agaaccttgt gagctggacg atgaagattt ccgctgcgtc 180 tgcaacttct ccgaacctca gcccgactgg tccgaagcct tccagtgtgt gtctgcagta 240 gaggtggaga tccatgccgg cggtctcaac ctagagccgt ttctaaagcg cgtcgatgcg 300 gacgccgacc cgcggcagta tgctgacacg gtcaaggctc tccgcgtgcg gcggctcaca 360 gtgggagccg cacaggttcc tgctcagcta ctggtaggcg ccctgcgtgt gctagcgtac 420 tcccgcctca aggaactgac gctcgaggac ctaaagataa ccggcaccat gcctccgctg 480 cctctggaag ccacaggact tgcactttcc agcttgcgcc tacgcaacgt gtcgtgggcg 540 acagggcgtt cttggctcgc cgagctgcag cagtggctca agccaggcct caaggtactg 600 agcattgccc aagcacactc gcctgccttt tcctgcgaac aggttcgcgc cttcccggcc 660 cttaccagcc tagacctgtc tgacaatcct ggactgggcg aacgcggact gatggcggct 720 ctctgtcccc acaagttccc ggccatccag aatctagcgc tgcgcaacac aggaatggag 780 acgcccacag gcgtgtgcgc cgcactggcg gcggcaggtg tgcagcccca cagcctagac 840 ctcagccaca actcgctgcg cgccaccgta aaccctagcg ctccgagatg catgtggtcc 900 agcgccctga actccctcaa tctgtcgttc gctgggctgg aacaggtgcc taaaggactg 960 ccagccaagc tcagagtgct cgatctcagc tgcaacagac tgaacagggc gccgcagcct 1020 gacgagctgc ccgaggtgga taacctgaca ctggacggga atcccttcct ggtccctgga 1080 actgccctcc cccacgaggg ctcaatgaac tccggcgtgg tcccagcctg tgcacgttcg 1140 accctgtcgg tgggggtgtc gggaaccctg gtgctgctcc aaggggcccg gggctttgcc 1200 taagatccaa gacagaataa tgaatggact caaactgcct tggcttcagg ggagtcccgt 1260 caggacgttg aggacttttc gaccaattca accctttgcc ccacctttat taaaatctta 1320 aacaacg 1327 <210> 222 <211> 3881 <212> DNA <213> HUMAN <400> 222 gccgcctccg cctctctctt tactgcggcg cggggcaagg tgtgcgggcg ggaaggggca 60 cgggcacccc cgcggtcccc gggaggctag agatcatgga agggaagtgg ttgctgtgta 120 tgttactggt gcttggaact gctattgttg aggctcatga tggacatgat gatgatgtga 180 ttgatattga ggatgacctt gacgatgtca ttgaagaggt agaagactca aaaccagata 240 ccactgctcc tccttcatct cccaaggtta cttacaaagc tccagttcca acaggggaag 300 tatattttgc tgattctttt gacagaggaa ctctgtcagg gtggatttta tccaaagcca 360 agaaagacga taccgatgat gaaattgcca aatatgatgg aaagtgggag gtagaggaaa 420 tgaaggagtc aaagcttcca ggtgataaag gacttgtgtt gatgtctcgg gccaagcatc 480 atgccatctc tgctaaactg aacaagccct tcctgtttga caccaagcct ctcattgttc 540 agtatgaggt taatttccaa aatggaatag aatgtggtgg tgcctatgtg aaactgcttt 600 ctaaaacacc agaactcaac ctggatcagc tccatgacaa gaccccttat acgattatgt 660 ttggtccaga taaatgtgga gaggactata aactgcactt catcttccga cacaaaaacc 720 ccaaaacggg tatctatgaa gaaaaacatg ctaagaggcc agatgcagat ctgaagacct 780 attttactga taagaaaaca catctttaca cactaatctt gaatccagat aatagttttg 840 aaatactggt tgaccaatct gtggtgaata gtggaaatct gctcaatgac atgactcctc 900 ctgtaaatcc ttcacgtgaa attgaggacc cagaagaccg gaagcccgag gattgggatg 960 aaagaccaaa aatcccagat ccagaagctg tcaagccaga tgactgggat gaagatgccc 1020 ctgctaagat tccagatgaa gaggccacaa aacccgaagg ctggttagat gatgagcctg 1080 agtacgtacc tgatccagac gcagagaaac ctgaggattg ggatgaagac atggatggag 1140 aatgggaggc tcctcagatt gccaacccta gatgtgagtc agctcctgga tgtggtgtct 1200 ggcagcgacc tgtgattgac aaccccaatt ataaaggcaa atggaagcct cctatgattg 1260 acaatcccag ttaccaggga atctggaaac ccaggaaaat accaaatcca gatttctttg 1320 aagatctgga acctttcaga atgactcctt ttagtgctat tggtttggag ctgtggtcca 1380 tgacctctga catttttttt gacaacttta tcatttgtgc tgatcgaaga atagttgatg 1440 attgggccaa tgatggatgg ggcctgaaga aagctgctga tggggctgct gagccaggcg 1500 ttgtggggca gatgatcgag gcagctgaag agcgcccgtg gctgtgggta gtctatattc 1560 taactgtagc ccttcctgtg ttcctggtta tcctcttctg ctgttctgga aagaaacaga 1620 ccagtggtat ggagtataag aaaactgatg cacctcaacc ggatgtgaag gaagaggaag 1680 aagagaagga agaggaaaag gacaagggag atgaggagga ggaaggagaa gagaaacttg 1740 aagagaaaca gaaaagtgat gctgaagaag atggtggcac tgtcagtcaa gaggaggaag 1800 acagaaaacc taaagcagag gaggatgaaa ttttgaacag atcaccaaga aacagaaagc 1860 cacgaagaga gtgaaacaat cttaagagct tgatctgtga tttcttctcc ctcctcccct 1920 gcaagagtgg tcctaggaga ggacctggca caccttaggt tgacattcag aaaacttcaa 1980 gacatcacca tcagcaggct ccagttgaac actagtctgt gtaactttaa acatctagca 2040 gtaaatactt gcagttgtga tataaaggac cctgtttctg tagaaaagaa aacatttaac 2100 ataatggttg tgaaatgtaa catgaagcaa actaactttt ttttttttaa catctttgtt 2160 tttaaaatag aatgatagaa ctttgccagt ctttaagatc ttggcttaat ttaatgtatt 2220 aatctgtttg tgcaaacata ataccaccat ttaaaaatgt tagggagatg agttgcagtt 2280 tttataatag atttttttta aagtttggta ttgtaaaaca ttcacacctc tgtccctcaa 2340 aattgataat tacgtttaaa gtgcagtcat ttgtggttag aatcttgttt tgtttgcttc 2400 cattattgag ttcctcctaa ggaaattgag gagagggact gaatagaagc ccaaattcat 2460 ataaaagttg cgtttaagtt gtattaaaaa tagatatata agaaaaaatt ctttcacttg 2520 atgtttgtta gaccagaaag tgtgtgtgtt ctgtagctca gttcccagac agctttttag 2580 gtagtggagg aggtggcttc atgtggcact tgggcattta tattccactt gggagggtca 2640 ggctgtggcc ttctggagca ggtggcttgt taaggaacgc tagcagggca tggcacgtga 2700 gctccggaat agatgtcttc atcacttctt ccactgtgtg ttgacactgt tttccttacc 2760 tatttcctca gatccccagc tttctcctct gctatgcatt ttcttcacag tgcagcttgc 2820 agtccgttgc tgaaaatgat tataagccct gcataatgtt aagctttatt gtgattacgt 2880 gtatgtttct tctttctttt aagcagaccc atacctttcc agggtcaaag tacagaatag 2940 aatacattga tacaaagtac agaaaaatac tttgattttt atccatttct tttactctgt 3000 gtaaagactt gagaagtcta attcacaggc aaaccaatac agaattgact gcagttgaac 3060 agactagaag tatttgtggg aggagtgaca tgaagcatga gttatctgat tttttttgta 3120 gctgctatat attttaagcc ttcatttgca attcatgtaa cagttgtgtc ataaattaca 3180 caataaagca gtcctgttca aatttttttt taacgtggct tgtagaattt ttaaaaaagt 3240 gatcttaggt ttgttttttc atgcgggatg cagatgggtg ctatcagagc ctctcccaca 3300 ccactatagt gtaataatgt tattattact ctacactgaa acgtattcag agttagatat 3360 tattttagct tcagttgttc tttagaggct ttcaaatgta ccgatgatac tgtttcttgc 3420 actgaatata taaacactcc acagtgttta tattgggaag atattgggaa ggaaatatat 3480 ttgtaaaaga tgaaggctgt atctattttt ttttcttttt aaagtttgtt cacttaaatt 3540 cttttgagga tgggatgtat ttttcttgct gttcagtgct ttttcctttt catctgttgt 3600 tctgtggtca cagtgacctt agctacatag cagactttcc caaatgtatt gattacaaat 3660 aaacagttgt tacttagcaa gacctgaaaa tatgtctgca ggtttctcct tgaagcaaat 3720 gtgtgggatc attgcatttc cagaaatctg cctccttcac cctccgttga cagtatatgt 3780 catgcctcac tttcttctag ctgagcttta aatcattaga gcttaaattg tcagatcgtt 3840 cattgccttt ccagggttat ttagtaaagt ttgttgaaaa c 3881 <210> 223 <211> 4519 <212> DNA <213> HUMAN <400> 223 cagccagggc caccccaggg gctataagag caactagatt tctggagcag ctcggggatg 60 ggtgccattt gagcccagct tggctccccc tcctggctgg cctccttcct gcccttctgc 120 ctgcctgtgt ctgctgagat tctgcaaaga ggaacgttgg caccatgtct ctgctcaacc 180 ctgtcctgct gccccccaag gtgaaggcct atctgagcca aggggagcgc ttcatcaaat 240 gggatgatga aactacagtt gcctctccag ttatcctccg tgtggatcct aagggctact 300 acttatactg gacgtatcaa agtaaggaga tggagtttct ggatatcacc agcatccggg 360 atactcgctt tgggaagttt gccaagatgc ccaagagcca gaagctccgg gacgtcttca 420 acatggactt tcctgataac agtttcctgc tgaagacact cacggtggtg tccggcccgg 480 acatggtgga cctcaccttc cacaacttcg tctcctacaa ggagaacgtg ggcaaggcct 540 gggctgagga cgtactggcc ctagtcaaac atccgctgac ggccaacgcc tcccgcagca 600 ccttcctgga caagatcctt gtgaagctca agatgcagct caactctgaa gggaagattc 660 cggtgaagaa ctttttccag atgtttcctg ctgaccgcaa gcgggtggaa gctgctctca 720 gtgcctgcca cctccccaaa ggcaaaaatg acgccatcaa tcctgaggac ttcccagaac 780 ctgtctacaa gagtttcctc atgagcctct gtcctcggcc agaaatagat gagatcttca 840 cttcttacca tgctaaggcc aaaccctaca tgacgaagga gcacctgacc aaattcatca 900 accagaaaca gcgggactcc cggcttaact ccctgctgtt cccgccagca cggcctgacc 960 aggtgcaggg cctcatcgac aagtatgagc ccagtggcat caatgcacag aggggccagc 1020 tgtcacctga aggcatggtc tggtttctct gtgggccaga gaacagcgtg ctggcccagg 1080 acaagctgct gctccaccac gacatgacgc agccactcaa tcattacttc atcaactcgt 1140 cccacaacac ctacctgaca gccggccagt tctcaggcct ctcctcggct gagatgtacc 1200 gccaggtgct gctctctggc tgccgttgcg tggagctaga ctgctggaag gggaaacccc 1260 ctgacgagga gcccattatc acccatggct tcaccatgac cacagacatc ttcttcaaag 1320 aagcaattga ggctattgca gaaagtgcct ttaagacctc cccctatccc atcatcctgt 1380 cgtttgagaa ccatgtggac tcaccccgcc agcaggctaa gatggctgag tattgccgga 1440 cgatctttgg ggatatgctg ctcacagagc ccctggaaaa gttcccacta aaaccaggtg 1500 tccccctgcc cagccctgag gatctcaggg gcaagatcct catcaagaac aagaagaacc 1560 agttttctgg ccccacctcc tccagtaagg ataccggtgg ggaggctgag ggcagcagcc 1620 cacccagtgc ccctgcagtg tgggctggcg aggaagggac tgagctggag gaggaggagg 1680 tggaagagga agaggaggag gagtcaggaa acctggatga agaagagatt aagaagatgc 1740 agtcggatga gggcacagcg ggcctggaag tgacggctta tgaggagatg tccagcctag 1800 tcaattacat ccagcccacc aagttcgtct cctttgagtt ctctgcccaa aagaaccgaa 1860 gttatgtcat ctcgtccttc acagagctca aggcatatga cctgctctcc aaggcctcgg 1920 tgcagtttgt ggactacaac aagcgccaga tgagccgcat ttaccccaag ggaacccgca 1980 tggactcctc caactacatg ccccagatgt tctggaatgc tggatgccag atggttgccc 2040 tcaacttcca gacgatggac ttgcccatgc agcagaacat ggcagtattt gagttcaacg 2100 ggcagagcgg ctacctcctc aagcatgagt tcatgcgccg gccggacaag cagttcaacc 2160 ccttctcagt ggaccgcatc gacgtggtgg tggccaccac cctttccatt acggtgatct 2220 ctgggcagtt cctgtcagaa cgcagcgtgc gcacctatgt agaagtggag ctgtttggcc 2280 ttcctgggga ccccaagagg cgctatcgaa ctaagctgtc acccagtact aactccatca 2340 atcctgtctg gaaggaggag ccctttgtct ttgagaagat cttgatgcct gagctggcct 2400 ccctcagagt ggctgtgatg gaggaaggca acaagtttct tggacaccgc atcatcccca 2460 tcaatgccct aaattctggg taccaccacc tgtgcctgca cagtgagagc aacatgcccc 2520 tcaccatgcc tgcgctcttc atcttcctgg agatgaagga ctacatacct ggtgcttggg 2580 cagatctcac tgtggccctc gccaacccca ttaagttctt cagtgcccat gacacgaagt 2640 ctgtgaagct caaggaggcc atgggaggtc tgcctgagaa gcccttccca ctggcgagtc 2700 cagttgccag ccaggtcaat ggggcgttgg ccccaacgag caatgggtca ccagcagcca 2760 gggccggggc cagggaagag gctatgaaag aagctgcgga gccgcggacc gccagcctgg 2820 aggagctccg ggagctaaag ggcgtggtga agctgcagcg gcggcacgag aaggagctgc 2880 gagagttgga gcggcgcgga gcgcggcgct gggaggagct gctgcagcgg ggcgcggcgc 2940 agctggcgga gctcgggcca ccgggcgtgg ggggcgtcgg ggcctgcaag ctcggtcccg 3000 gcaagggctc tcgcaagaag aggagcctgc cccgcgagga gagcgccgga gccgcgccgg 3060 gcgagggccc tgagggcgtg gacgggcgcg tgcgggagct gaaagacagg ctggagctgg 3120 agctgctgcg gcagggcgag gagcagtacg agtgcgttct gaagcgcaag gagcagcacg 3180 tggccgagca aatctccaaa atgatggagc tggccagaga gaaacaggcg gcagagctga 3240 aggccctgaa ggagacgtcg gagaacgaca ccaaagagat gaagaaaaag ctggagacaa 3300 agagactgga gcggatccag ggcatgacca aagtcaccac agacaagatg gcccaggaga 3360 ggttgaagag agagattaac aactcccaca tccaggaagt agtgcaggtg atcaagcaga 3420 tgacggagaa cttggagagg caccaggaga agctggagga gaagcaggcg gcttgcctgg 3480 aacagatacg ggagatggaa aagcagttcc agaaggaggc gctggcagag tacgaggcca 3540 ggatgaaggg tctggaggca gaggtgaagg agtcggtgag ggcctgcctc aggacctgct 3600 ttccctccga ggccaaggac aagcctgaga gggcctgcga gtgcccccca gagctgtgtg 3660 agcaggaccc actcatagca aaggcagatg cccaggagag ccgcctctga tgcccccatc 3720 ccactgggac atttagcaag gaggttcagc cccttctctg ggatgtggtt ctattccccc 3780 aggaaaaagg agccccagcc ttctgaggct gtgggaacct gtggctgcct tggacgctgc 3840 agccccctcc tcaacggcca ggccagagtc tgagacagga cccaggcacc ctcacggcag 3900 ggcctctctg gggcctagaa gtcttctcaa gctgacttcc tacctccccc tccatctcta 3960 gataagtgtc atatatttgt tgagggcaaa agactatgga ctggaaggca gaaagtggga 4020 tcctggcccc actctgcctt tcctattgag caaccagctc tgggctcagt ttcctcacct 4080 ggagggttgg acccactcac ctccactcta gccccgaacc ctcctgcccc aggcttccag 4140 gccccatcag gcctgccctg agttggcctt gtccactcct tgaggcagat cctggcacta 4200 cctcacagct ccctggggac ggccactccc tggctgaggg ccctcccctc ccctctgcct 4260 gtccggaacg ggaggctgaa atggaaaagc tgccttggcc ctgcttggct gagtcacaag 4320 gggcagtggg ctcttgggtg ctgttccacc ctgaccctgg ctcacccctc ttcctaggcc 4380 tgggggcagg cagttcctac catgtacccc tctcaggctg cctgcctgac aaggtcagca 4440 tcatttgctc tcctgaattt atgaggttta tttatttttc tctttcctac tcctattaaa 4500 gaacctcgtc ccagtgaaa 4519 <210> 224 <211> 429 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(429) <223> N=any base <400> 224 caaaatggca ccacactgtt ttatttaaac ctgcaaacaa tataaagagg taaggacttc 60 tgacgccaaa ccatgcaagt aataacaaag gaacagagaa nnatattant aacaaaaaga 120 aaatcattaa aaataaaaaa acaaagtact tcacatttca cagcagtgct ttggcagtac 180 tggcangcat ttctggtcaa ctgcttccna cagcaggaat atgaagaaac ccccagatct 240 tagcaaangt gtaacaacat tttctccctg acagcttaca ttccaagtca ttccatncca 300 taccgctcca ctccacagtt ttatanacct gatcttaaga tgtaactagg tactatgtgt 360 gctcacaatt aaaaacttaa ctaaanacaa atcagagggt agcagacaag tnaacaaagt 420 ttccagtaa 429 <210> 225 <211> 487 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(487) <223> N=any base <400> 225 gcgncncgag ggtgngacac cttctcacag gggatcatgt actcgccctg aatcagcggc 60 acggccccga tggccttctg cagctcgcgc acctcatcca ccgggcccac catgagggaa 120 gtgcctgtgt ccacaatggc ctcacagccc tccttgcaca gggtcagccc gctggccacc 180 tccacctggt ccaggtggac ctggccagta ggcttgcggg tgacattcag gtaggacaga 240 gaacccttgt aatacttgga gtctgtgcca cccagcatca gctcaccccc aggctgcgca 300 tctgggtccc tgctcaggta gaaggagaag atgttctggt ccaccagctt ctgctgcatc 360 aggttgtccg aagaggggca gcacnttgtt gacggagatg cgggggtagg ccatgcccag 420 gatgccatcg aacttggctg cgatgaaggt gatgcctggc tgcttggtgg ctcccaaaga 480 cctgcta 487 <210> 226 <211> 426 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(426) <223> N=any base <400> 226 gactttttag ctgctcactg gccccgnttg tntggccgac tcatccgccc gcgaccccta 60 atcccctctg cctgccccaa gatgctgaag ccagccctgg agccccgagg gtntcntcct 120 tcgagaactg ccaaagaaat ncatcattgg aacgcgtcct cccggggntc aaggtccctc 180 acgcacgcaa gaccgggacc accatcgcgg gcntgggtgt tccaagacgg ggtcattctg 240 ggcgccgata cgcgagccac taacgattcg gtcgtgggcg gacaaagagc tgcgagaagn 300 tccacttcat cgcccccaaa atctaacttg ctgtgggggc tgggagtagc cgcgggaagn 360 cgagnatgaa ccacaaggat gggtgggctt ccaagatgga agctaacaag gntttatcta 420 aggggc 426 <210> 227 <211> 397 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(397) <223> N=any base <400> 227 ataactctgt cttcgtgagc tggatggcaa gctctcacac tttacccgca gctgtgctgt 60 gacttcccac acagtgtctg agcagaggcg gcgtgggacc agaccctctc ccacagccag 120 cctggncaag gtggcacaga ccagagctct gtgcagacaa gcacccaggg gtctaggaat 180 gctcccttct ctccaggggc cagaggggag aaccaagctg ctcagccttc cttgctctgg 240 ccagcaggag gcccttntcc tgggagcagc cctcgtttct gcctgtcatg cccgagggac 300 acaagggcca tccacttgtg cttcctgctt acatgggggc acttgcttgg ggatgttgct 360 tcccacttct tgaggtnttc ccccacccag ggggcct 397 <210> 228 <211> 455 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(455) <223> N=any base <400> 228 ttgcattnat agattttatt gtaaaacaga gctgaagtca caggaagtag ggaactttgc 60 acccaacata tacagcattc attcgctgag tacctgccaa gagcgaggct aggtgcttgg 120 ccctgcagga ccntgagaca tatacgagtc atgtttcctg ctctgcnagc tcccagcccg 180 gtggggagac aggcagaggc acagcatctt tcatacaagt ntccaagtgc cagaagctct 240 acaatgtcaa ggagcaattt attccttcag cagaggaaga aagaaccccc aggngccaca 300 tttgctcaga gccttgggag ctgagaaact tctgatagga ggtaaagtac tgcaggcagc 360 tgtaaaaaat ctgggagtgg gagatgggag cttnggaggc tgggcagcag tgcctgggac 420 agagggantc cagnttttgg aagtgtttta aaagg 455 <210> 229 <211> 3632 <212> DNA <213> HUMAN <400> 229 aaagagctgg aggcgcgcag gccggctccg ctccggcccc ggacgatgcg gcgcgcccag 60 gatgctgccg tgcctcgtag tgctgctggc ggcgctcctc agcctccgtc ttggctcaga 120 cgctcatggg acagagctgc ccagccctcc gtctgtgtgg tttgaagcag aatttttcca 180 ccacatcctc cactggacac ccatcccaaa tcagtctgaa agtacctgct atgaagtggc 240 gctcctgagg tatggaatag agtcctggaa ctccatctcc aactgtagcc agaccctgtc 300 ctatgacctt accgcagtga ccttggacct gtaccacagc aatggctacc gggccagagt 360 gcgggctgtg gacggcagcc ggcactccaa ctggaccgtc accaacaccc gcttctctgt 420 ggatgaagtg actctgacag ttggcagtgt gaacctagag atccacaatg gcttcatcct 480 cgggaagatt cagctaccca ggcccaagat ggcccccgcg aatgacacat atgaaagcat 540 cttcagtcac ttccgagagt atgagattgc cattcgcaag gtgccgggaa acttcacgtt 600 cacacacaag aaagtaaaac atgaaaactt cagcctccta acctctggag aagtgggaga 660 gttctgtgtc caggtgaaac catctgtcgc ttcccgaagt aacaagggga tgtggtctaa 720 agaggagtgc atctccctca ccaggcagta tttcaccgtg accaacgtca tcatcttctt 780 tgcctttgtc ctgctgctct ccggagccct cgcctactgc ctggccctcc agctgtatgt 840 gcggcgccga aagaagctac ccagtgtcct gctcttcaag aagcccagcc ccttcatctt 900 catcagccag cgtccctccc cagagaccca agacaccatc cacccgcttg atgaggaggc 960 ctttttgaag gtgtccccag agctgaagaa cttggacctg cacggcagca cagacagtgg 1020 ctttggcagc accaagccat ccctgcagac tgaagagccc cagttcctcc tccctgaccc 1080 tcacccccag gctgacagaa cgctgggaaa cggggagccc cctgtgctgg gggacagctg 1140 cagtagtggc agcagcaata gcacagacag cgggatctgc ctgcaggagc ccagcctgag 1200 ccccagcaca gggcccacct gggagcaaca ggtggggagc aacagcaggg gccaggatga 1260 cagtggcatt gacttagttc aaaactctga gggccgggct ggggacacac agggtggctc 1320 ggccttgggc caccacagtc ccccggagcc tgaggtgcct ggggaagaag acccagctgc 1380 tgtggcattc cagggttacc tgaggcagac cagatgtgct gaagagaagg caaccaagac 1440 aggctgcctg gaggaagaat cgcccttgac agatggcctt ggccccaaat tcgggagatg 1500 cctggttgat gaggcaggct tgcatccacc agccctggcc aagggctatt tgaaacagga 1560 tcctctagaa atgactctgg cttcctcagg ggccccaacg ggacagtgga accagcccac 1620 tgaggaatgg tcactcctgg ccttgagcag ctgcagtgac ctgggaatat ctgactggag 1680 ctttgcccat gaccttgccc ctctaggctg tgtggcagcc ccaggtggtc tcctgggcag 1740 ctttaactca gacctggtca ccctgcccct catctctagc ctgcagtcaa gtgagtgact 1800 cgggctgaga ggctgctttt gattttagcc atgcctgctc ctctgcctgg accaggagga 1860 gggccctggg gcagaagtta ggcacgaggc agtctgggca cttttctgca agtccactgg 1920 ggctggccca gccaggctgc agggctggtc agggtgtctg gggcaggagg aggccaactc 1980 actgaactag tgcagggtat gtgggtggca ctgacctgtt ctgttgactg gggccctgca 2040 gactctggca gagctgagaa gggcagggac cttctccctc ctaggaactc tttcctgtat 2100 cataaaggat tatttgctca ggggaaccat ggggctttct ggagttgtgg tgaggccacc 2160 aggctgaagt cagctcagac ccagacctcc ctgcttaggc cactcgagca tcagagcttc 2220 cagcaggagg aagggctgta ggaatggaag cttcagggcc ttgctgctgg ggtcattttt 2280 aggggaaaaa ggaggatatg atggtcacat ggggaacctc ccctcatcgg gcctctgggg 2340 caggaagctt gtcactggaa gatcttaagg tatatatttt ctggacactc aaacacatca 2400 taatggattc actgagggga gacaaaggga gccgagaccc tggatggggc ttccagctca 2460 gaacccatcc ctctggtggg tacctctggc acccatctgc aaatatctcc ctctctccaa 2520 caaatggagt agcatccccc tggggcactt gctgaggcca agccactcac atcctcactt 2580 tgctgcccca ccatcttgct gacaacttcc agagaagcca tggttttttg tattggtcat 2640 aactcagccc tttgggcggc ctctgggctt gggcaccagc tcatgccagc cccagagggt 2700 cagggttgga ggcctgtgct tgtgtttgct gctaatgtcc agctacagac ccagaggata 2760 agccactggg cactgggctg gggtccctgc cttgttggtg ttcagctgtg tgattttgga 2820 ctagccactt gtcagagggc ctcaatctcc catctgtgaa ataaggactc cacctttagg 2880 ggaccctcca tgtttgctgg gtattagcca agctggtcct gggagaatgc agatactgtc 2940 cgtggactac caagctggct tgtttcttat gccagaggct aacagatcca atgggagtcc 3000 atggtgtcat gccaagacag tatcagacac agccccagaa gggggcatta tgggccctgc 3060 ctccccatag gccatttgga ctctgccttc aaacaaaggc agttcagtcc acaggcatgg 3120 aagctgtgag gggacaggcc tgtgcgtgcc atccagagtc atctcagccc tgcctttctc 3180 tggagcattc tgaaaacaga tattctggcc cagggaatcc agccatgacc cccacccctc 3240 tgccaaagta ctcttaggtg ccagtctggt aactgaactc cctctggagg caggcttgag 3300 ggaggattcc tcagggttcc cttgaaagct ttatttattt attttgttca tttatttatt 3360 ggagaggcag cattgcacag tgaaagaatt ctggatatct caggagcccc gaaattctag 3420 ctctgacttt gctgtttcca gtggtatgac cttggagaag tcacttatcc tcttggagcc 3480 tcagtttcct catctgcaga ataatgactg acttgtctaa ttcataggga tgtgaggttc 3540 tgctgaggaa atgggtatga atgtgccttg aacacaaagc tctgtcaata agtgatacat 3600 gttttttatt ccaataaatt gtcaagacca ca 3632 <210> 230 <211> 4839 <212> DNA <213> HUMAN <400> 230 atgtcggcgg gcggccgtga cgaggagcgg cggaagctgg ccgacatcat ccaccactgg 60 aacgccaacc ggctggacct gttcgagatc agccagccga ccgaggattt ggagttccat 120 ggagtgatga gattttattt tcaagataaa gctgctggaa actttgcaac aaaatgtatt 180 cgggtctcta gtactgccac cactcaagat gtaatcgaaa cgctcgcgga gaaatttcga 240 cctgatatgc gaatgctgtc ctctcccaag tattcactct atgaagtgca tgtcagcgga 300 gaaagaagat tggatataga tgagaaacct ctagttgtac aactgaattg gaacaaagat 360 gatcgggaag gcagatttgt tcttaagaat gagaatgacg ccattcctcc taaggctcaa 420 agtaatggac ctgaaaagca ggaaaaagaa ggggttatcc agaacttcaa gagaactctc 480 tcaaagaaag aaaagaagga aaaaaagaag agagaaaaag aggcattgcg acaggcatct 540 gataaagatg atagaccttt ccaaggggag gatgttgaaa attctcgact ggctgctgag 600 gtttacaaag acatgccgga aaccagcttt actcgaacca tttctaatcc tgaggtggtt 660 atgaaacgac ggaggcagca aaaattggaa aagagaatgc aggaatttcg gagctcagat 720 gggcggcctg attcaggtgg aacattgaga atttatgcag atagtttaaa accaaatatt 780 ccctacaaga caatcctgct gtctactaca gatcctgcag actttgctgt ggctgaagct 840 ttagagaagt atggtctgga aaaagaaaac cctaaggatt actgcatcgc ccgggttatg 900 cttcctcctg gagcccagca ttctgatgaa aagggtgcta aagaaattat tcttgatgat 960 gatgagtgtc ctttacaaat cttcagggaa tggccaagtg acaaagggat tttagtcttt 1020 cagttgaaga ggaggccacc agaccacatc ccaaagaaaa ccaagaaaca cttggaaggc 1080 aagacaccca agggaaagga gagagctgac gggtctgtct atggctccac ccttcctccg 1140 gagaagctgc cctatttagt agagttaagc ccagatggtt ctgactctag agataagcca 1200 aagctttacc gccttcagtt aagtgttact gaagttggga cagaaaagtt ggatgacaac 1260 tctatccagt tgtttggccc aggaattcag ccccatcact gtgaccttac caacatggat 1320 ggagtggtca ctgtgacgcc cagaagtatg gacgcagaaa cctacgtgga aggccagcgc 1380 atctcagaaa ccaccatgct gcagagtggc atgaaagtgc agtttggggc gtcccatgta 1440 tttaagtttg tggaccccag tcaggatcat gctcttgcaa aaagatctgt ggatggaggc 1500 ctgatggtta agggcccaag acataaacct ggaattgttc aggagacaac ttttgatttg 1560 ggaggagata ttcatagtgg gacagcatta ccgacaagca agagcaccac taggctggac 1620 agcgacagag tgtcgtctgc ctctagcaca gccgagcggg gaatggtgaa gccgatgatc 1680 agagtagaac agcagccaga ttatcgcagg caagaaagca gaacacagga tgcttctggg 1740 cctgagctga tactacctgc aagcattgaa ttcagggaaa gttctgaaga ttcatttttg 1800 tctgccatta taaattatac taatagctct acagtccact ttaagttgtc ccctacatat 1860 gtattatata tggcatgccg gtatgtattg tccaaccagt acagacctga catcagccct 1920 acagagcgca cacataaagt cattgcagtc gtcaacaaga tggtgagcat gatggagggt 1980 gtcatccaga aacagaagaa tattgcaggg gcacttgcct tctggatggc aaatgcatct 2040 gaacttctca acttcattaa gcaagaccga gaccttagtc ggatcacact ggatgctcaa 2100 gatgttttag cacatttggt tcaaatggca tttaaatact tggttcactg tcttcaatca 2160 gaacttaata attacatgcc agcctttcta gatgaccctg aagagaacag tctgcaacga 2220 ccaaaaatag atgatgtgct gcacacgctc acaggagcca tgtccttgct acgacgctgc 2280 agagtcaatg ccgccctgac catccagctc ttctctcagc tcttccactt catcaatatg 2340 tggctgttca atagattggt gaccgaccca gattcggggc tgtgctccca ttactggggt 2400 gcgattatcc gtcagcagtt gggccatatt gaagcctggg ctgagaagca ggggctggaa 2460 ctggctgcgg actgtcatct gagcaggatc gtgcaggcaa cgactttgct taccatggat 2520 aagtatgcac ctgatgacat tccaaatata aacagcacct gctttaagtt aaattcatta 2580 caacttcaag ccttattaca gaactatcac tgtgcacctg atgagccttt tatcccaacg 2640 gatcttatag aaaatgtagt gactgtggct gaaaacactg ccgatgagct ggcccgcagt 2700 gatggaaggg aagtgcagtt ggaggaggat cctgatctgc agctgccgtt tcttttgcca 2760 gaagatggtt attcttgtga tgttgtcaga aacattccaa atggtttaca agaattttta 2820 gaccctctgt gccagagagg attttgcagg ttaattcctc acacacgttc accaggtact 2880 tggacaatat attttgaagg tgcagattat gaaagtcacc ttctgcgtga gaacacagag 2940 ctggctcagc ctctgaggaa agaacctgaa ataatcactg tgaccctaaa aaagcagaat 3000 ggaatgggcc ttagcattgt tgcagcaaag ggtgctggtc aagataaact aggaatctac 3060 gtgaagtcgg ttgtgaaagg aggtgctgca gatgtggatg gacgtctagc tgcaggtgat 3120 cagctcctca gtgtggatgg acgaagtctg gttggactct ctcaggaaag ggcggcagaa 3180 ctcatgacaa gaacaagctc tgtggtgaca ctggaagtag caaagcaggg tgccatctac 3240 cacggtctgg ccacccttct caatcagcca tcccccatga tgcagagaat ttcagatcgt 3300 cgtggctcag gtaaaccccg accaaagagt gaaggctttg agctctataa taattcaact 3360 caaaatgggt ctcctgagag tcctcagctg ccttgggcag aatatagtga accaaagaaa 3420 ttgcctggtg atgacagact gatgaaaaat agagctgatc accgttccag ccccaacgta 3480 gcaaatcagc ctcctagtcc tggagggaaa agtgcatatg cctctggaac aacagcgaag 3540 ataacatctg tctctactgg aaacctctgc actgaggagc agacgcctcc gcctagacct 3600 gaagcctacc ccattcccac tcagacgtac accagagagt attttacctt cccagcttcc 3660 aaatcccagg atcggatggc tcctcctcag aaccagtggc caaattatga ggaaaagcca 3720 catatgcaca cagatagtaa tcattccagt attgcaattc agcgtgttac acgttcccaa 3780 gaagaacttc gagaagataa agcttaccaa cttgagcggc atcgaataga ggcagctatg 3840 gaccgaaagt ctgatagtga tatgtggata aatcagagct cctcactgga ctccagtacc 3900 tctagccagg agcatctgaa ccattcctct aagtcggtca cccctgcttc cacactgacc 3960 aaaagtggcc ctggccgttg gaaaacacca gcagccatac cggccacccc tgtggccgtc 4020 tcccagccaa tccgaacaga cctgcctccg ccacccccgc cacctccagt ccactatgcc 4080 ggtgatttcg atggaatgtc catggatttg cctctcccac cacccccttc cgccaaccag 4140 atagggctgc cgtctgcgca ggtggctgct gctgaacgga gaaagagaga agaacatcag 4200 cgttggtatg agaaggagaa ggcccccctg gaggaggagc gggagaggaa gcggagagag 4260 caggagagga agttgggcca gatgcgcact cagtccttaa accctgctcc gttttctccc 4320 ctgactgcac agcagatgaa gcccgaaaag ccttccacac tccagcggcc acaggaaaca 4380 gtcattcggg agctgcagcc tcagcagcag ccccgcacga tcgagcgcag agacttgcag 4440 tacattacag tcagcaaaga ggagctttcc tcgggggaca gtctgtcccc cgacccgtgg 4500 aagcgggacg ccaaggagaa gctggagaag cagcagcaga tgcacatcgt ggacatgctg 4560 agcaaggaga tccaggagct ccagagcaaa ccggaccgca gcgccgagga gagcgaccgg 4620 ctgcgcaagc tcatgctgga gtggcagttc cagaagagac tccaggagtc gaagcagaag 4680 gacgaagatg acgaggagga ggaggacgat gatgtggaca ccatgctgat catgcagcgc 4740 ctggaggctg aacgaagagc gagggtaaag gggggagtgc tttggctgtg cccatctgtg 4800 gtccctattt tagcttctgc gtgtttccca tggggatag 4839 <210> 231 <211> 2947 <212> DNA <213> HUMAN <400> 231 ggcgggaaac agcttagtgg gtgtggggtc gcgcattttc ttcaaccagg aggtgaggag 60 gtttcgacat ggcggtgcag ccgaaggaga cgctgcagtt ggagagcgcg gccgaggtcg 120 gcttcgtgcg cttctttcag ggcatgccgg agaagccgac caccacagtg cgccttttcg 180 accggggcga cttctatacg gcgcacggcg aggacgcgct gctggccgcc cgggaggtgt 240 tcaagaccca gggggtgatc aagtacatgg ggccggcagg agcaaagaat ctgcagagtg 300 ttgtgcttag taaaatgaat tttgaatctt ttgtaaaaga tcttcttctg gttcgtcagt 360 atagagttga agtttataag aatagagctg gaaataaggc atccaaggag aatgattggt 420 atttggcata taaggcttct cctggcaatc tctctcagtt tgaagacatt ctctttggta 480 acaatgatat gtcagcttcc attggtgttg tgggtgttaa aatgtccgca gttgatggcc 540 agagacaggt tggagttggg tatgtggatt ccatacagag gaaactagga ctgtgtgaat 600 tccctgataa tgatcagttc tccaatcttg aggctctcct catccagatt ggaccaaagg 660 aatgtgtttt acccggagga gagactgctg gagacatggg gaaactgaga cagataattc 720 aaagaggagg aattctgatc acagaaagaa aaaaagctga cttttccaca aaagacattt 780 atcaggacct caaccggttg ttgaaaggca aaaagggaga gcagatgaat agtgctgtat 840 tgccagaaat ggagaatcag gttgcagttt catcactgtc tgcggtaatc aagtttttag 900 aactcttatc agatgattcc aactttggac agtttgaact gactactttt gacttcagcc 960 agtatatgaa attggatatt gcagcagtca gagcccttaa cctttttcag ggttctgttg 1020 aagataccac tggctctcag tctctggctg ccttgctgaa taagtgtaaa acccctcaag 1080 gacaaagact tgttaaccag tggattaagc agcctctcat ggataagaac agaatagagg 1140 agagattgaa tttagtggaa gcttttgtag aagatgcaga attgaggcag actttacaag 1200 aagatttact tcgtcgattc ccagatctta accgacttgc caagaagttt caaagacaag 1260 cagcaaactt acaagattgt taccgactct atcagggtat aaatcaacta cctaatgtta 1320 tacaggctct ggaaaaacat gaaggaaaac accagaaatt attgttggca gtttttgtga 1380 ctcctcttac tgatcttcgt tctgacttct ccaagtttca ggaaatgata gaaacaactt 1440 tagatatgga tcaggtggaa aaccatgaat tccttgtaaa accttcattt gatcctaatc 1500 tcagtgaatt aagagaaata atgaatgact tggaaaagaa gatgcagtca acattaataa 1560 gtgcagccag agatcttggc ttggaccctg gcaaacagat taaactggat tccagtgcac 1620 agtttggata ttactttcgt gtaacctgta aggaagaaaa agtccttcgt aacaataaaa 1680 actttagtac tgtagatatc cagaagaatg gtgttaaatt taccaacagc aaattgactt 1740 ctttaaatga agagtatacc aaaaataaaa cagaatatga agaagcccag gatgccattg 1800 ttaaagaaat tgtcaatatt tcttcaggct atgtagaacc aatgcagaca ctcaatgatg 1860 tgttagctca gctagatgct gttgtcagct ttgctcacgt gtcaaatgga gcacctgttc 1920 catatgtacg accagccatt ttggagaaag gacaaggaag aattatatta aaagcatcca 1980 ggcatgcttg tgttgaagtt caagatgaaa ttgcatttat tcctaatgac gtatactttg 2040 aaaaagataa acagatgttc cacatcatta ctggccccaa tatgggaggt aaatcaacat 2100 atattcgaca aactggggtg atagtactca tggcccaaat tgggtgtttt gtgccatgtg 2160 agtcagcaga agtgtccatt gtggactgca tcttagcccg agtaggggct ggtgacagtc 2220 aattgaaagg agtctccacg ttcatggctg aaatgttgga aactgcttct atcctcaggt 2280 ctgcaaccaa agattcatta ataatcatag atgaattggg aagaggaact tctacctacg 2340 atggatttgg gttagcatgg gctatatcag aatacattgc aacaaagatt ggtgcttttt 2400 gcatgtttgc aacccatttt catgaactta ctgccttggc caatcagata ccaactgtta 2460 ataatctaca tgtcacagca ctcaccactg aagagacctt aactatgctt tatcaggtga 2520 agaaaggtgt ctgtgatcaa agttttggga ttcatgttgc agagcttgct aatttcccta 2580 agcatgtaat agagtgtgct aaacagaaag ccctggaact tgaggagttt cagtatattg 2640 gagaatcgca aggatatgat atcatggaac cagcagcaaa gaagtgctat ctggaaagag 2700 agcaaggtga aaaaattatt caggagttcc tgtccaaggt gaaacaaatg ccctttactg 2760 aaatgtcaga agaaaacatc acaataaagt taaaacagct aaaagctgaa gtaatagcaa 2820 agaataatag ctttgtaaat gaaatcattt cacgaataaa agttactacg tgaaaaatcc 2880 cagtaatgga atgaaggtaa tattgataag ctattgtctg taatagtttt atattgtttt 2940 atattaa 2947 <210> 232 <211> 279 <212> DNA <213> HUMAN <400> 232 atgaagctct gcgtgtctgc cttctctctc ctcctgcttg tggccgcctt ctgcgattca 60 gtgctgtcag caccaatagg ctctgaccct cccacttcct gctgcttctc ttacacctcc 120 cggaagattc atcggaactt tgtgatggat tactatgaga ccagcagcct ttgctcccag 180 ccagctgtgg tatttctgac caaaaaaggc aggcaaatct gtgccgaccc cagcgagccc 240 tgggtcaatg agtatgtgaa tgacttggag ttgaactga 279 <210> 233 <211> 2109 <212> DNA <213> HUMAN <400> 233 tcctcctctc ctgaccgtat tctaggatcc tctctgctct tacctcctgc cattccaagg 60 cctccttctg aacctggcct caacccagtc ccaagtttgc accgcccgag gcaggatagg 120 ggtccctcca ttttgatttc ctaaagagaa taagactggc tagttcagaa ccctaagtcc 180 agggcagccc aatcagcagt ggaagaggct ccacagcagt gggcctgacc accttcccct 240 ctcctaggtg caggcggagc tgaggcggaa gtggcggcgc tggcacctgc agggcgtcct 300 gggctggaac cccaaatacc ggcacccgtc gggaggcagc aacggcgcca cgtgcagcac 360 gcaggtttcc atgctgaccc gcgtcagccc aggtgcccgc cgctcctcca gcttccaagc 420 cgaagtctcc ctggtctgac caccaggatc ccaggggccc aaggcggccc ctcccgcccc 480 ttcccactca ccccggcaga cgccggggac agaggcctgc ccgggcgcgg ccagccccgg 540 ccctgggctc ggaggctgcc cccggccccc tggtctctgg tccggacact cctagagaac 600 gcagccctag agcctgcctg gagcgtttct agcaagtgag agagatggga gctcctctcc 660 tggaggattg caggtggaac tcagtcatta gactcctcct ccaaaggccc cctacgccaa 720 tcaagggcaa aaagtctaca tactttcatc ctgactctgc cccctgctgg ctcttctgcc 780 caattggagg aaagcaaccg gtggatcctc aaacaacact ggtgtgacct gagggcagaa 840 aggttctgcc cggggaaggt caccagcacc aacaccacgg tagtgcctga aatttcacca 900 ttgctgtcaa gttcctttgg gttaagcatt accactcagg catttgactg aagatgcagc 960 tcactaccct attctctctt tacgcttagt tatcagcttt ttaaagtggg ttattctgga 1020 gtttttgttt ggagagcaca cctatcttag tggttcccca ccgaagtgga ctggcccctg 1080 ggtcagtctg gtgggaggac ggtgcaaccc aaggactgag ggactctgaa gcctctggga 1140 aatgagaagg cagccaccag cgaatgctag gtctcggact aagcctacct gctctccaag 1200 tctcagtggc ttcatctgtc aagtgggatc tgtcacacca gccatactta tctctctgtg 1260 ctgtggaagc aacaggaatc aagagctgcc ctccttgtcc acccacctat gtgccaactg 1320 ttgtaactag gctcagagat gtgcacccat gggctctgac agaaagcaga tacctcaccc 1380 tgctacacat acaggatttg aactcagatc tgtctgatag gaatgtgaaa gcacggactc 1440 ttactgctaa cttttgtgta tcgtaaccag ccagatcctc ttggttattt gtttaccact 1500 tgtattatta atgccattat cctgaattcc ccttgccacc ccaccctccc tggcgtgtgg 1560 ctgaggaggc ctccatctca tgtatcatct ggataggagc ctgctggtca cagcctcctc 1620 tgtctgccct tcaccccagt ggccactcag cttcctaccc acacctctgc cagaagatcc 1680 cctcaggact gcaacaggct tgtgcaacaa taaatgttgg cttggattgg cttggttccc 1740 ctggtggttg atattctcaa tatggcctaa aatgggacca gcttccaact tggagccatc 1800 ttcctccacc caaaggatgg gtgatctaat acattactga aaccagatgc ctcaactctt 1860 ttggcttttg acagaaatcc atattttcat atgaggcatt cacagttctg agggccttca 1920 gctcccatct ttttgagtgg tatcctctct cctctgagtg tgatgaagac caggtcccca 1980 ttgtgtcccc ccactgcata tgtatggacc cactccagat ggcacgggga cggggggagt 2040 aggaaaagtg gcatggtgag cagagccctg gctatcaggt ggcagatggc agagttggaa 2100 ggaatcttg 2109 <210> 234 <211> 1820 <212> DNA <213> HUMAN <400> 234 gagctccaag ctggtttgaa caagccctgg gcatgtttgg cgggaagttg gcttagctcg 60 gctacctgtg gccccgcagt tttgtagtcc ccgccttgtt tctccccaga ggcctctcaa 120 tcctccctcc atgatcttcg catagagcac agtacccctt cacacggagg acgcgatggc 180 tcccaagaaa cgcccagaaa cccagaagac ctccgagatt gtattacgcc ccaggaacaa 240 gaggagcagg agtcccctgg agctggagcc cgaggccaag aagctctgtg cgaagggctc 300 cggtcctagc agaagatgtg actcagactg cctctgggtg gggctggctg gcccacagat 360 cctgccacca tgccgcagca tcgtcaggac cctccaccag cataagctgg gcagagcttc 420 ctggccatct gtccagcagg ggctccagca gtcctttttg cacactctgg attcttaccg 480 gatattacaa aaggctgccc cctttgacag gagggctaca tccttggcgt ggcacccaac 540 tcaccccagc accgtggctg tgggttccaa agggggagat atcatgctct ggaattttgg 600 catcaaggac aaacccacct tcatcaaagg gattggagct ggagggagca tcactgggct 660 gaagtttaac cctctcaata ccaaccagtt ttacgcctcc tcaatggagg gaacaactag 720 gctgcaagac tttaaaggca acattctacg agtttttgcc agctcagaca ccatcaacat 780 ctggttttgt agcctggatg tgtctgctag tagccgaatg gtggtcacag gagacaacgt 840 ggggaacgtg atcctgctga acatggacgg caaagagctt tggaatctca gaatgcacaa 900 aaagaaagtg acgcatgtgg ccctgaaccc atgctgtgat tggttcctgg ccacagcctc 960 cgtagatcaa acagtgaaaa tttgggacct gcgccaggtt agagggaaag ccagcttcct 1020 ctactcgctg ccgcacaggc atcctgtcaa cgcagcttgt ttcagtcccg atggagcccg 1080 gctcctgacc acggaccaga agagcgagat ccgagtttac tctgcttccc agtgggactg 1140 ccccctgggc ctgatcccgc accctcaccg tcacttccag cacctcacac ccatcaaggc 1200 agcctggcat cctcgctaca acctcattgt tgtgggccga tacccagatc ctaatttcaa 1260 aagttgtacc ccttatgaat tgaggacgat cgacgtgttc gatggaaact cagggaagat 1320 gatgtgtcag ctctatgacc cagaatcttc tggcatcagt tcgcttaatg aattcaatcc 1380 catgggggac acgctggcct ctgcaatggg ttaccacatt ctcatctgga gccaggagga 1440 agccaggaca cggaagtgag agacactaaa gaaggtgtgg gccagacaag gccttggagc 1500 ccacacatgg gatcaagtcc tgcaagcaga ggtggtgatt tgttaaaggg ccaaaagtat 1560 ccaaggttag ggttggagca ggggtgctgg gacctggggc actgtgggac tgggacactt 1620 ttatgttaat gctctggact tgcctccaga gactgctcca gagttggtga cacagctgtc 1680 ccaagggccc ctctgtatct agcctggaac caaggttatc ttggaactaa atgacttttc 1740 tcctctcagt gggtggtagc agagggatca agcagttatt tgatttgtgc tcttttgata 1800 tggccaataa aaccataccg 1820 <210> 235 <211> 1077 <212> DNA <213> HUMAN <400> 235 aattcggcac gagggacttt gaacatgtcg gggatcgccc tcagcagact cgcccaggag 60 aggaaagcat ggaggaaaga ccacccattt ggtttcgtgg ctgtcccaac aaaaaatccc 120 gatggcacga tgaacctcat gaactgggag tgcgccattc caggaaagaa agggactccg 180 tgggaaggag gcttgtttaa actacggatg cttttcaaag atgattatcc atcttcgcca 240 ccaaaatgta aattcgaacc accattattt cacccgaatg tgtacccttc ggggacagtg 300 tgcctgtcca tcttagagga ggacaaggac tggaggccag ccatcacaat caaacagatc 360 ctattaggaa tacaggaact tctaaatgaa ccaaatatcc aagacccagc tcaagcagag 420 gcctacacga tttactgcca aaacagagtg gagtacgaga aaagggtccg agcacaagcc 480 aagaagtttg cgccctcata agcagcgacc ttgtggcatc gtcaaaagga agggattggt 540 ttggcaagaa cttgtttaca acatttttgc aaatctaaag ttgctccata caatgactag 600 tcacctgggg gggttgggcg ggcgccatct tccattgccg ccgcgggtgt gcggtctcga 660 ttcgctgaat tgcccgtttc catacagggt ctcttccttc ggtcttttgt atttttgatt 720 gttatgtaaa actcgctttt attttaatat tgatgtcagt atttcaactg ctgtaaaatt 780 ataaactttt atacttgggt aagtccccca gggcgagttc ctcgctctgg gatgcaggca 840 tgcttctcac cgtgcagagc tgcacttggc ctcagctggc tgtatggaaa tgcaccctcc 900 ctcctgccgc tcctctctag aaccttctag aacctgggct gtgctgcttt tgagcctcag 960 accccagggc agcatctcgg ttctgcgcca cttcctttgt gttatatggc gttttgtctg 1020 tgttgctgtt tagagtaaat aaactgttta tataaaaaaa aaaaaaaaaa aactcga 1077 <210> 236 <211> 2569 <212> DNA <213> HUMAN <400> 236 tccctcgtct ctctcgggca acatggcggg cgtggaggag gtagcggcct ccgggagcca 60 cctgaatggc gacctggatc cagacgacag ggaagaagga gctgcctcta cggctgagga 120 agcagccaag aaaaaaagac gaaagaagaa gaagagcaaa gggccttctg cagcagggga 180 acaggaacct gataaagaat caggagcctc agtggatgaa gtagcaagac agttggaaag 240 atcagcattg gaagataaag aaagagatga agatgatgaa gatggagatg gcgatggaga 300 tggagcaact ggaaagaaga agaaaaagaa gaagaagaag agaggaccaa aagttcaaac 360 agaccctccc tcagttccaa tatgtgacct gtatcctaat ggtgtatttc ccaaaggaca 420 agaatgcgaa tacccaccca cacaagatgg gcgaacagct gcttggagaa ctacaagtga 480 agaaaagaaa gcattagatc aggcaagtga agagatttgg aatgattttc gagaagctgc 540 agaagcacat cgacaagtta gaaaatacgt aatgagctgg atcaagcctg ggatgacaat 600 gatagaaatc tgtgaaaagt tggaagactg ttcacgcaag ttaataaaag agaatggatt 660 aaatgcaggc ctggcatttc ctactggatg ttctctcaat aattgtgctg cccattatac 720 tcccaatgcc ggtgacacaa cagtattaca gtatgatgac atctgtaaaa tagactttgg 780 aacacatata agtggtagga ttattgactg tgcttttact gtcactttta atcccaaata 840 tgatacgtta ttaaaagctg taaaagatgc tactaacact ggaataaagt gtgctggaat 900 tgatgttcgt ctgtgtgatg ttggtgaggc catccaagaa gttatggagt cctatgaagt 960 tgaaatagat gggaagacat atcaagtgaa accaatccgt aatctaaatg gacattcaat 1020 tgggcaatat agaatacatg ctggaaaaac agtgccgatt gtgaaaggag gggaggcaac 1080 aagaatggag gaaggagaag tatatgcaat tgaaaccttt ggtagtacag gaaaaggtgt 1140 tgttcatgat gatatggaat gttcacatta catgaaaaat tttgatgttg gacatgtgcc 1200 aataaggctt ccaagaacaa aacacttgtt aaatgtcatc aatgaaaact ttggaaccct 1260 tgccttctgc cgcagatggc tggatcgctt gggagaaagt aaatacttga tggctctgaa 1320 gaatctgtgt gacttgggca ttgtagatcc atatccacca ttatgtgaca ttaaaggatc 1380 atatacagcg caatttgaac ataccatcct gttgcgtcca acatgtaaag aagttgtcag 1440 cagaggagat gactattaaa cttagtccaa agccacctca acacctttat tttctgagct 1500 ttgttggaaa acatgatacc agaattaatt tgccacatgt tgtctgtttt aacagtggac 1560 ccatgtaata cttttatcca tgtttaaaaa agaaggaatt tggacaaagg caaaccgtct 1620 aatgtaatta accaacgaaa aagctttccg gacttttaaa tgctaactgt ttttcccctt 1680 cctgtctagg aaaatgctat aaagctcaaa ttagttagga atgacttata cgttttgttt 1740 tgaataccta agagatactt tttggatatt tatattgcca tattcttact tgaatgcttt 1800 gaatgactac atccagttct gcacctatac cctctggtgt tgctttttaa ccttcctgga 1860 atccattttc taaaaaataa agacacattc ttctcagcac cacacaacac ctattccaaa 1920 atcgaccaca tatttggaag taaagctctc ctcagcaaat gtaaaagaac agaaattata 1980 acaaactgtc tctcagacca cagtataacc aaactagaac tcaggattaa gaaactcact 2040 caaaaccaca caactacatg gaaactgaac aacctgctcc tgaatgacta ctggatacat 2100 aacaaaatga aggcagaaat aaagatgttc tttaaaacca atgagaacaa agacacaaca 2160 taccagaatc tctgggacac attcaaagca gtgtgtagag ggaaatttat agcactaaat 2220 gcccacaaga gaaagcagga aatatctaaa attgacaccc taacatcaca attaaaagaa 2280 ctagagaagc aagagcaaac acattgaaaa gctaagagaa ggcaagaaat aactaagatc 2340 agagcagaac tgaaggaaat agagacacaa aaaactcttc aaaaaatcaa tgaatccagg 2400 agctggtttt ttgaaacgat caacaaaatt gatagacact agcaagacta ataaagaaga 2460 aaggagagaa gaatcaaata gaagcaataa aaaatgataa aggggatatc accaccaatc 2520 ccacagaaat aaaccaccat cagagaatac tacaaacacc tctacgcaa 2569 <210> 237 <211> 724 <212> DNA <213> HUMAN <400> 237 gagcatacac cgagagagtg aggagccaga cgacaagcac acactatggc gctgaaacgg 60 attaataagg aacttagtga tttggcccgt gaccctccag cacaatgttc tgcaggtcca 120 gttggggatg atatgtttca ttggcaagcc acaattatgg gacctaatga cagcccatat 180 caaggcggtg tattcttttt gacaattcat tttcctacag actacccctt caaaccacct 240 aaggttgcat ttacaacaag aatttatcat ccaaatatta acagtaatgg cagcatttgt 300 ctcgatattc taagatcaca gtggtcgcct gctttaacaa tttctaaagt tcttttatcc 360 atttgttcac tgctatgtga tccaaaccca gatgaccccc tagtgccaga gattgcacgg 420 atctataaaa cagacagaga taagtacaac agaatatctc gggaatggac tcagaagtat 480 gccatgtgat gctaccttaa agtcagaata acctgcatta tagctggaat aaactttaaa 540 ttactgttcc ttttttgatt ttcttatccg gctgctcccc tgatcagacc tcatcttttt 600 taattttatt ttttgtttac ctccctccat tcattcacat gctcatctga gaagacttaa 660 gttcttccag ctttgacaat aactgctttt agaaactgta aagtagttac aagagaacag 720 ttgg 724 <210> 238 <211> 3755 <212> DNA <213> HUMAN <400> 238 ggcggctgcg gcacgggaaa ggctcagtga ctgaagctcc aaaggccagc aggctggtgg 60 ggacgtgacc gaagcgaggc tctggttccc tttcggtggg cgccatttga gcctcatctc 120 tggcttcccc aggatgcgcc ggcagccggg gagcggctcc gggcgcgagg tctgaggatg 180 atctttcctg tcgcccgcta cgcgctccgg tggctgcgac ggcccgaaga ccgtgccttt 240 tcccgcgccg ccatggagat ggccctccga ggcgtgcgga aagtcctctg tgtggccgaa 300 aaaaacgacg cggccaaggg gatcgccgac ctgctgtcaa acggtcgcat gaggcggaga 360 gaaggacttt caaaattcaa caagatctat gaatttgatt atcatctgta tggccagaat 420 gttaccatgg taatgacttc agtttctgga catttactgg ctcatgattt ccagatgcag 480 tttcgaaaat ggcagagctg caaccctctt gtcctctttg aagcagaaat tgaaaagtac 540 tgcccagaga attttgtaga catcaagaaa actttggaac gagagactcg ccagtgccag 600 gctctggtga tctggactga ctgtgataga gaaggcgaaa acatcgggtt tgagattatc 660 cacgtgtgta aggctgtaaa gcccaatctg caggtgttgc gagcccgatt ctctgagatc 720 acaccccatg ccgtcaggac agcttgtgaa aacctgaccg agcctgatca gagggtgagc 780 gatgctgtgg atgtgaggca ggagctggac ctgaggattg gagctgcctt tactaggttc 840 cagaccctgc ggcttcagag gatttttcct gaggtgctgg cagagcagct catcagttac 900 ggcagctgcc agttccccac actgggcttt gtggtggagc ggttcaaagc cattcaggct 960 tttgtaccag aaatcttcca cagaattaaa gtaactcatg accacaaaga tggtatcgta 1020 gaattcaact ggaaaaggca tcgactcttt aaccacacgg cttgcctagt tctctatcag 1080 ttgtgtgtgg aggatcccat ggcaactgtg gtagaggtca gatctaagcc caagagcaag 1140 tggcggcctc aagccttgga cactgtggag cttgagaagc tggcttctcg aaagttgaga 1200 ataaatgcta aagaaaccat gaggattgct gagaagctct acactcaagg gtacatcagc 1260 tatccccgaa cagaaacaaa catttttccc agagacttaa acctgacggt gttggtggaa 1320 cagcagaccc ccgatccacg ctggggggcc tttgcccaga gcattctaga gcggggtggt 1380 cccaccccac gcaatgggaa caagtctgac caagctcacc ctcccattca ccccaccaaa 1440 tacaccaaca acttacaggg agatgaacag cgactgtacg agtttattgt tcgccatttc 1500 ctggcttgct gctcccagga tgctcagggg caggagacca cagtggagat cgacatcgct 1560 caggaacgct ttgtggccca tggcctcatg attctggccc gaaactatct ggatgtgtat 1620 ccatatgatc actggagtga caagatcctc cctgtctatg agcaaggatc ccactttcag 1680 cccagcaccg tggagatggt ggacggggag accagcccac ccaagctgct caccgaggcc 1740 gacctcattg ccctcatgga gaagcatggc attggtacgg atgccactca tgcggagcac 1800 atcgagacca tcaaagcccg gatgtacgtg ggcctcaccc cagacaagcg gttcctccct 1860 gggcacctgg gcatgggact tgtggaaggt tatgattcca tgggctatga aatgtctaag 1920 cctgacctcc gggctgaact ggaagctgat ctgaagctga tctgtgatgg caaaaaggac 1980 aaatttgtgg ttctaaggca gcaagtgcag aaatacaagc aggttttcat tgaagcggtg 2040 gctaaagcaa agaaattgga cgaggccttg gcccagtact ttgggaatgg gacagagttg 2100 gcccagcaag aagatatcta cccagccatg ccagagccca tcaggaagtg cccacagtgc 2160 aacaaggaca tggtccttaa gaccaagaag aatggcgggt tctacctcag ctgcatgggt 2220 ttcccagagt gtcgctcagc tgtgtggctt cctgactcgg tgctggaggc cagcagggac 2280 agcagtgtgt gtccagtttg tcagccacac cctgtgtaca ggttaaagtt aaagtttaag 2340 cgcggtagcc ttcccccgac catgcctctg gagtttgttt gctgcatcgg cggatgcgac 2400 gacaccctga gggagatcct ggacctgaga ttttcagggg gcccccccag ggctagccag 2460 ccctctggcc gcctgcaggc taaccagtcc ctgaacagga tggacaacag ccagcacccc 2520 cagcctgctg acagcagaca gactgggtcc tcaaaggctc tggcccagac cctcccacca 2580 cccacggctg ctggtgaaag caattctgtg acctgcaact gtggccagga ggctgtgctg 2640 ctcactgtcc gtaaggaggg ccccaaccgg ggccggcagt tctttaagtg caacggaggt 2700 agctgcaact tcttcctgtg ggcagacagc cccaatccgg gagcaggagg gcctcctgcc 2760 ttggcatata gacccctggg cgcctccctg ggatgcccac caggcccagg gatccaccta 2820 ggtgggtttg gcaaccctgg tgatggcagt ggtagtggca catcctgcct ttgcagccag 2880 ccctccgtca cacggactgt gcagaaggat ggacccaaca aggggcgcca gttccacaca 2940 tgtgccaagc cgagagagca gcagtgtggc tttttccagt gggtcgatga gaacaccgct 3000 ccagggactt ctggagcccc gtcctggaca ggagacagag gaagaaccct ggagtcggaa 3060 gccagaagca aaaggccccg ggccagttcc tcagacatgg ggtccacagc aaagaaaccc 3120 cggaaatgca gcctttgcca ccagcctgga cacacccgtc ccttttgtcc tcagaacaga 3180 tgagctcagg gtagggtaga gaacgccact ttctcagacc tgtccccttt gtgtttagaa 3240 atgagttaac caggaccaag tggccattta gtgtcctgga aacttagagg acagtgttgg 3300 cctttggagt cgggccttct tgtgttaagg ggcacaaggt ccagatcact ctggagcagg 3360 ccagctctgc tggacagtga ccctcttccc aggcctcagg agtgaccata gccactgctg 3420 aaaagtcacg cagctgctcc ctcggacccc ccaaggatgg ttgctgttag cagaggattg 3480 gtgcagtccc agctgaagcc cactgtgtgc caaaggaaga agctcccagg gctgcttcct 3540 tcacctgcag aaagccccaa gtgagccacc agcactcatg gggcagtccc tgtccaggct 3600 gcccagggct tctcatagac gtcctgagaa ggacggtgta atgcaaggaa atggctgtgg 3660 taacactgat ccttcagaag aagcttcatt ccctcttaat ctagttaagc caggacatcc 3720 agaattcatt gctttaataa agaacccagg ccggg 3755 <210> 239 <211> 1986 <212> DNA <213> HUMAN <400> 239 catgattccc aagcttggca cgagggtccg caagcccggc tgagagcgcg ccatggggca 60 ggcgggctgc aaggggctct gcctgtcgct gttcgactac aagaccgaga agtatgtcat 120 cgccaagaac aagaaggtgg gcctgctgta ccggctgctg caggcctcca tcctggcgta 180 cctggtcgta tgggtgttcc tgataaagaa gggttaccaa gacgtcgaca cctccctgca 240 gagtgctgtc atcaccaaag tcaagggcgt ggccttcacc aacacctcgg atcttgggca 300 gcggatctgg gatgtcgccg actacgtcat tccagcccag gaaaagaacg tcttttttgt 360 ggtcaccaac ctgattgtga cccccaacca gcggcagaac gtctgtgctg agaatgaagg 420 cattcctgat ggcgcgtgct ccaaggacag cgactgccac gctggggaag cggttacagc 480 tggaaacgga gtgaagaccg gccgctgcct gcggagagag aacttggcca ggggcacctg 540 tgagatcttt gcctggtgcc cgttggagac aagctccagg ccggaggagc cattcctgaa 600 ggaggccgaa gacttcacca ttttcataaa gaaccacatc cgtttcccca aattcaactt 660 ctccaacaat gtgatggacg tcaaggacag atctttcctg aaatcatgcc actttggccc 720 caagaaccac tactgcccca tcttccgact gggctccgtg atccgctggg ccgggagcga 780 cttccaggat atagccctgg agggtggcgt gataggaatt aatattgaat ggaactgtga 840 tcttgataaa gctgcctctg agtgccaccc tcactattct tttagccgtc tggacaataa 900 actttcaaag tctgtctcct ccgggtacaa cttcagattt gccagatatt accgagacgc 960 agccggggtg gagttccgca ccctgatgaa agcctacggg atccgctttg acgtgatggt 1020 gaacggcaag ggtgcctcct tctgcgacct ggtactcatc tacctcatca aaaagagaga 1080 gttttaccgt gacaagaagt accaggaagt gaggggccta gaagacagtt cccaggaggc 1140 cgaggacgag gcatcggggc tggggctatc tgagcagctc acatctgggc cagggctgct 1200 ggggatgccg gagcagcagg agctgcagga gccacccgag gcgaacgttg gaagcagcag 1260 tcagaagggg aacggatctg tgtgcccaca gctcctggag ccccacagga gcacgtgaat 1320 tgcctctgct tacgttcagg ccctgtccta aacccagccg tctagcaccc agtgatccca 1380 tgcctttggg aatcccagga tgctgcccaa cgggaaattt gtacattggg tgctatgaat 1440 gccacatcac agggaccagc catcacagag caaagtgacc tccacgtctg atgctggggt 1500 catcaggacg gacccatcat ggctatcttt ttgccccacc ccctgccgtc agttcttcct 1560 ttctccgtgg ctggcttccc gcactaggga acgggttgta aatggggaac atgacttcct 1620 tccggagtcc ttgagcacct cagctaagga ccgcagtgcc ctgtagagtt cctagattac 1680 ctcactggga atagcattgt gcgtgtccgg aaaagggctc catttggttc cagcccactc 1740 ccctctgcaa gtgccgcagc ttccctcagg catactctcc agtggatcca agtactctct 1800 ctcctaaaga caccaccttc ctgccagctg tttgccctta ggccagtaca cagaattgaa 1860 agtgggggag gtggcagacg ctttctggga cctgcccaag atatgtattc tctgacactc 1920 ttatttggtc ataaaacaat aaatggtgtc aatttcaaaa aaaaaaaaaa aaaaaaaaaa 1980 aaaaaa 1986 <210> 240 <211> 1791 <212> DNA <213> HUMAN <400> 240 gcacgagcga ccatagctct ccaggtcaat ggccagcaag gaggggggtc cgagccggcg 60 gcggcggcgg cagtggtggc agcgggagac aaatggaaac ctccacaggg cacagactcc 120 atcaagatgg agaacgggca gagcacagcc gccaagctgg ggctgcctcc cctgacgccc 180 gagcagcagg aggcccttca gaaggccaag aagtacgcca tggagcagag catcaagagt 240 gtgctggtga agcagaccat cgcgcaccag cagcagcagc tcaccaacct gcagatggcg 300 gctcagcggc agggggcgct ggccatcatg tgccgcgtct acgtgggctc tatctactat 360 gagctggggg aggacaccat ccgccaggcc tttgccccct ttggccccat caagagcatc 420 gacatgtcct gggactccgt caccatgaag cacaagggct ttgccttcgt ggagtatgag 480 gtccccgaag ctgcacagct ggccttggag cagatgaact cggtgatgct ggggggcagg 540 aacatcaagg tgggcagacc cagcaacata gggcaggccc agcccatcat agaccagttg 600 gctgaggagg cacgggcctt caaccgcatc tacgtggcct ctgtgcacca ggacctctca 660 gacgatgaca tcaagagcgt gtttgaggcc tttggcaaga tcaagtcctg cacactggcc 720 cgggacccca caactggcaa gcacaagggc tacggcttca ttgagtacga gaaggcccag 780 tcgtcccaag atgctgtgtc ttccatgaac ctctttgacc tgggtggcca gtacttgcgg 840 gtgggcaagg ctgtcacacc gcccatgccc ctactcacac cagccacgcc tggaggcctc 900 ccacctgccg ctgctgtggc agctgctgca gccactgcca agatcacagc tcaggaagca 960 gtggccggag cagcggtgct gggtaccctg ggcacacctg gactggtgtc cccagcactg 1020 accctggccc agcccctggg cactttgccc caggctgtca tggctgccca ggcacctgga 1080 gtcatcacag gtgtgacccc agcccgtcct cctatcccgg tcaccatccc ctcggtggga 1140 gtggtgaacc ccatcctggc cagccctcca acgctgggtc tcctggagcc caagaaggag 1200 aaggaagaag aggagctgtt tcccgagtca gagcggccag agatgctgag cgagcaggag 1260 cacatgagca tctcgggcag tagcgcccga cacatggtga tgcagaagct gctccgcaag 1320 caggagtcta cagtgatggt tctgcgcaac atggtggacc ccaaggacat cgatgatgac 1380 ctggaagggg aggtgacaga ggagtgtggc aagttcgggg ccgtgaaccg cgtcatcatc 1440 taccaagaga aacaaggcga ggaggaggat gcagaaatca ttgtcaagat ctttgtggag 1500 ttttccatag cctctgagac tcataaggcc atccaggccc tcaatggccg ctggtttgct 1560 ggccgcaagg tggtggctga agtgtacgac caggagcgtt ttgataacag tgacctctct 1620 gcgtgacagt ggtccctctc cccggacttg cacttgttcc ttgtttcctc tgggttttat 1680 agtgatacag tggtgtcccc ggggccaggc gcgctctgcc cagcccagcc tacagtgcgg 1740 ataaaggtgc ggatgctgct ggccctgaaa aaaaaaaaaa aaaaactcga g 1791 <210> 241 <211> 2613 <212> DNA <213> HUMAN <400> 241 tcttggtctc ggctcctggc ccagtgctct ttcccatgtg tctgaatctg catcttgggc 60 aggggtccct gggccccact cctggacccc cggactgacc cccaccccat cttgtgctta 120 gcagattctt cccctggtgg ccatgggacc caggtcaatg tcacctgcat cgtgaacgtc 180 tgtagcagct ctgaccacag ctcacagtgc tcctcccaag ccagctccac aatgggagac 240 acagattcca gcccctcgga gtccccgaag gacgagcagg tccccttctc caaggaggaa 300 tgtgcctttc ggtcacagct ggagacgcca gagaccctgc tggggagcac cgaagagaag 360 cccctgcccc ttggagtgcc tgatgctggg atgaagccca gttaaccagg ccggtgtggg 420 ctgtgtcgta gccaaggtgg gctgagccct ggcaggatga ccctgcgaag gggccctggt 480 ccttccaggc ccccaccact aggactctga ggctctttct gggccaagtt cctctagtgc 540 cctccacagc cgcagcctcc ctctgacctg caggccaaga gcagaggcag cgagttgggg 600 aaagcctctg ctgccatggt gtgtccctct cggaaggctg gctgggcatg gacgttcggg 660 gcatgctggg gcaagtccct gactctctgt gacctgcccc gcccagctgc acctgccagc 720 ctggcttctg gagcccttgg gttttttgtt tgtttgtttg tttgtttgtt tgtttctccc 780 cctgggctct gcccagctct ggcttccaga aaaccccagc atccttttct gcagaggggc 840 tttctggaga ggagggatgc tgcctgagtc acccatgaag acaggacagt gcttcagcct 900 gaggctgaga ctgcgggatg gtcctggggc tctgtgtagg gaggaggtgg cagccctgta 960 gggaacgggg tccttcaagt tagctcagga ggcttggaaa gcatcacctc aggccaggtg 1020 cagtggctca cgcctatgat cccagcactt tgggaggctg aggcgggtgg atcacctgag 1080 gttaggagtt cgagaccagc ctggccaaca tggtaaaacc ccatctctac taaaaataca 1140 gaaattagcc gggcgtggtg gcgggcacct atagtcccag ctactcagaa gcctgaggct 1200 gggaaatcgt ttgaacccgg gaagcggagg ttgcagggag ccgagatcac gccactgcac 1260 tccagcctgg gcgacagagc gagagtctgt ctcaaaagaa aaaaaaaaaa gcaccgcctc 1320 caaatgctaa cttgtccttt tgtaccatgg tgtgaaagtc agatgcccag agggcccagg 1380 caggccacca tattcagtgc tgtggcctgg gcaagataac gcacttctaa ctagaaatct 1440 gccaattttt taaaaaagta agtaccactc aggccaacaa gccaacgaca aagccaaact 1500 ctgccagcca catccaaccc cccacctgcc atttgcaccc tccgccttca ctccggtgtg 1560 cctgcagccc cgcgcctcct tccttgctgt cctaggccac accatctcct ttcagggaat 1620 ttcaggaact agagatgact gagtcctcgt agccatctct ctactcctac ctcagcctag 1680 accctcctcc tcccccagag gggtgggttc ctcttcccca ctccccacct tcaattcctg 1740 ggccccaaac gggctgccct gccactttgg tacatggcca gtgtgatccc aagtgccagt 1800 cttgtgtctg cgtctgtgtt gcgtgtcgtg ggtgtgtgta gccaaggtcg gtaagttgaa 1860 tggcctgcct tgaagccact gaagctggga ttcctcccca ttagagtcag ccttccccct 1920 cccagggcca gggccctgca gaggggaaac cagtgtagcc ttgcccggat tctgggagga 1980 agcaggttga ggggctcctg gaaaggctca gtctcaggag catggggata aaggagaagg 2040 catgaaattg tctagcagag caggggcagg gtgataaatt gttgataaat tccactggac 2100 ttgagcttgg cagctgaact attggagggt gggagagccc agccattacc atggagacaa 2160 gaagggtttt ccaccctgga atcaagatgt cagactggct ggctgcagtg acgtgcacct 2220 gtactcagga ggctgagggg aggatcactg gagcccagga gtttgaggct gcagcgagct 2280 atgatcgcgc cactacactc cagcctgagc aacagagtga gaccctgtct cttaaagaaa 2340 aaaaaagtca gactgctggg actggccagg tttctgccca cattggaccc acatgaggac 2400 atgatggagc gcacctgccc cctggtggac agtcctggga gaacctcagg cttccttggc 2460 atcacagggc agagccggga agcgatgaat ttggagactc tgtggggcct tggttccctt 2520 gtgtgtgtgt gttgatccca agacaatgaa agtttgcact gtatgctgga cggcattcct 2580 gcttatcaat aaacctgttt gttttaaaaa aaa 2613 <210> 242 <211> 2149 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(2149) <223> N=any base <400> 242 gacatggcca acatcgcggt gcagcgaatc aagcgggagt tcaaggaggt gctgaagagc 60 gaggagacga gcaaaaatca aattaaagta gatcttgtag atgagaattt tacagaatta 120 agaggagaaa tagcaggacc tccagacaca ccatatgaag gaggaagata ccaactagag 180 ataaaaatac cagaaacata cccatttaat ccccctaagg tccggtttat cactaaaata 240 tggcatccta atattagttc cgtcacaggg gctatttgtt tggatatcct gaaagatcaa 300 tgggcagctg caatgactct ccgcacggta ttattgtcat tgcaagcact attggcagct 360 gcagagccag atgatccaca ggatgctgta gtagcaaatc agtacaaaca aaatcccgaa 420 atgttcaaac agacagctcg actttgggca catgtgtatg ctggagcacc agtttctagt 480 ccagaataca ccaaaaaaat agaaaaccta tgtgctatgg gctttgatag gaatgcagta 540 atagtggcct tgtcttcaaa atcatgggat gtagagactg caacagaatt gcttctgagt 600 aactgaggca tagagagctg ctgatatagt caagcttgcc tcttcttgag gagcaccaac 660 atctgttatt tttaggattc tgcatagatt tcttttaatc tggcattctc gcctaatgat 720 gttatctagg caccattgga gactgaaaaa aaaaaatccc tgctctgtaa ataaagctaa 780 ttaaacgtct gtgtaaattt aaaaagggga aatactttaa ttttttttct taatagtgta 840 aaaattccct gagctaagct aaaaccatgg aagaaacatg ctactttagt gtttagcagt 900 gtaccaagac tagcaagagt ttgcttcagg atttggttga ataattaaga taatatttgg 960 agtgtgtcag ggccattcaa attgttggtg ttgcatcaca gctaccttaa ctgtttttaa 1020 catggatcct ctgtgcctgt gaatttactt gcatgcttgt acttgacttc ttaggatggg 1080 tagctgaaaa gaccaccatt ttaagcattt gagaattctt aaatatgaaa tttattcaga 1140 attgaagatg gtgacctatt cagagccttt ttgtccttgt caacagactg ggacagtgtc 1200 tgattccccc ttcacccccc cccacccccg ccttggcaca cacagctaat attctaatgg 1260 taaatttctc tgtatcaggt ggggaaatgt gctgaaggac agtatgtatc ccttgcttca 1320 tttttaggtc gtaggtttgg aatgtcttgt cccagttctt caaacactct taaatttttc 1380 ttaagtaatg taaaaatgga actgccaatt ttatttctct tgcaaaaata gtaaatactt 1440 gatgttacat tattcccagg tttaatgaaa gaacccaact tagtttttca gtgaatttga 1500 cacctatttt ttagtgatga aatttttctt tgagaactgg caaggatgca gtcagctgtt 1560 tgcagttttt agcctgattt tggggtctat agagattgct ttattggata cttcaagtca 1620 ttcttgcttg cacttcccct attgacacat gaaagctgtg ttggtgtttt attgtacata 1680 cttcagatgc acataggaat agaagtgtgt tataaatcta gctttcttta tgatgtttct 1740 gataatacga gaattgaaaa ctttaccttc tcttgtacat agtcagacta tttgtattaa 1800 atttacattt cattctaagt tccaaaagtt tgaaaattat tagttttgca agatcacaca 1860 ctaatgtaac cattttatga aggttgaagt ggatttatgc aggcagttct atatatagaa 1920 atncaattct ttttaaattt ttaggaccaa tacaaaataa cacaaatgta atggaatcag 1980 actgaattaa agtaaggctg tatattgaaa gtcatattat aaaaggtttg ctttctttaa 2040 gtgttattta tcttaaatta taatcgttaa atgtttggaa gataattttt gaatcataac 2100 gtcagcataa cttcatttga cttctcaata atcttgtcga cgcggccgc 2149 <210> 243 <211> 3343 <212> DNA <213> HUMAN <400> 243 tcccagccgg ctgaggcggg cagggccggg cggggccgcg ccacggagtc cacagcccgg 60 cgctccctgc cgcgccgccg ccgcaccgcg ccccacagga gaagacgaac cgggcccggc 120 ggccgaagcg gcccgcgagg cgcgggaggc atgaagttgg gcgcgcacgg gcctcgaagc 180 ggcggggagc cgggagccgc ccgcatctag agcccgcgag gtgcgtgcgc catggagcta 240 gggggccccg gagcgccgcg gctgctgccg ccgctgctgc tgcttctggg gaccggcctc 300 ctgcgcgcca gcagccatgt ggagacccgg gcccacgccg aggagcggct cctgaagaaa 360 ctcttctccg gttacaacaa gtggtcccga cccgtggcca acatctcgga cgtggtcctc 420 gtccgcttcg gcctgtccat cgctcagctc attgacgtgg atgagaagaa ccagatgatg 480 accacgaacg tatgggtgaa gcaggagtgg cacgactaca agctgcgctg ggacccagct 540 gactatgaga atgtcacctc catccgcatc ccctccgagc tcatctggcg gccggacatc 600 gtcctctaca acaatgctga cggggacttc gcggtcaccc acctgaccaa ggcccacctg 660 ttccatgacg ggcgggtgca gtggactccc ccggccattt acaagagctc ctgcagcatc 720 gacgtcacct tcttcccctt cgaccagcag aactgcacca tgaaattcgg ctcctggacc 780 tacgacaagg ccaagatcga cctggtgaac atgcacagcc gcgtggacca gctggacttc 840 tgggagagtg gcgagtgggt catcgtggac gccgtgggca cctacaacac caggaagtac 900 gagtgctgcg ccgagatcta cccggacatc acctatgcct tcgtcatccg gcggctgccg 960 ctcttctaca ccatcaacct catcatcccc tgcctgctca tctcctgcct caccgtgctg 1020 gtcttctacc tgccctccga gtgtggcgag aagatcacgc tgtgcatctc cgtgctgctg 1080 tcgctcaccg tcttcctgct gctcatcacc gagatcatcc cgtccacctc actggtcatc 1140 ccactcatcg gcgagtacct gctgttcacc atgatcttcg tcaccctgtc catcgtcatc 1200 acggtcttcg tgctcaacgt gcaccaccgc tcgccacgca cgcacaccat gcccacctgg 1260 gtacgcaggg tcttcctgga catcgtgcca cgcctgctcc tcatgaagcg gccgtccgtg 1320 gtcaaggaca attgccggcg gctcatcgag tccatgcata agatggccag tgccccgcgc 1380 ttctggcccg agccagaagg ggagccccct gccacgagcg gcacccagag cctgcaccct 1440 ccctcaccgt ccttctgcgt ccccctggat gtgccggctg agcctgggcc ttcctgcaag 1500 tcaccctccg accagctccc tcctcagcag cccctggaag ctgagaaagc cagcccccac 1560 ccctcgcctg gaccctgccg cccgccccac ggcacccagg caccagggct ggccaaagcc 1620 aggtccctca gcgtccagca catgtccagc cctggcgaag cggtggaagg cggcgtccgg 1680 tgccggtctc ggagcatcca gtactgtgtt ccccgagacg atgccgcccc cgaggcagat 1740 ggccaggctg ccggcgccct ggcctctcgc aacacccact cggctgagct cccaccccca 1800 gaccagccct ctccgtgcaa atgcacatgc aagaaggagc cctcttcggt gtccccgagc 1860 gccacggtca agacccgcag caccaaagcg ccgcccccgc acctgcccct gtcgccggcc 1920 ctgacccggg cggtggaggg cgtccagtac attgcagacc acctgaaggc cgaagacaca 1980 gacttctcgg tgaaggagga ctggaagtac gtggccatgg tcatcgaccg catcttcctc 2040 tggatgttca tcatcgtctg cctgctgggg acggtgggcc tcttcctgcc gccctggctg 2100 gctggcatga tctaggaagg gaccgggagc ctgcgtggcc tggggctgcc gtgcacgggg 2160 ccagcatcca tgcggccggc ctggggccgg gctggcttct ccctggactc tgtggggcca 2220 cacgtttgcc aaattttcct tcctgttctg tgtctgctgt aagacggcct tggacgggga 2280 cacggcctct ggggagaccg agtgtggagc tgcttccagt tggactgtgg cctcaggagg 2340 cagtggcttg gagcagaggt gggggtcgcc gccttctacc tgcaggactc gggctaagtc 2400 cagctctccc cctgcgcagc cctccgcggc ggacaggaac accagcccca gcgagtctgg 2460 agaccaggac tctgccttcc aggcgtaggg ccagggctct ggcaggtggc cagggctcca 2520 cggggggcta gtggcttcag cccctggggt acttctgtgt tgtgattccc cggagctggg 2580 aaggtcccga atggagtcca gacctgggcc ctggttcccc caggaccctg agggtttcca 2640 ccttggcgcg cagcccggga gatccgccct gggctctggg ttcgggaaga aggacttcct 2700 gctacagtag ctgtggggag ctggtggggg catccttgag gacctccacc tgggagatgc 2760 tgggaccctc ggggcaggaa gtccctgaga agcctcatgg gagtcaggga gccctggggt 2820 ttccacacag gcccatgccc tccgtcctgg cagggcaggc agagctcagc acagcctcac 2880 ccctgcaggc ggtatccaga ggtgagggag gcctgaaatg tttccaggca tgaccctgga 2940 gcccggcagt gcacccccta aagatggcgc acccggcagc cccccattgt ccccaggggc 3000 acacttcccc cttgggatgg gcacagcctg ccccacccct ccatgattcc aagggccaag 3060 aggggcgggg ccaggatggc ttttcccctg cctgtgagtg acatcggttc aggaggagac 3120 agtcaggaag cctcctgctg agtggtccac attctgctgc ccccagaccc catccagcca 3180 ggggtgggga tggggttggg ctctgcgtcc cactgagtct cattcctctg tccccgagcc 3240 gagctctcct gggccagggt ctcgtcagga ggtgcctgag agcagaatga ataattgagg 3300 ttaggaaccc ggcatgccga gtgccccaga aatgccgctg tgt 3343 <210> 244 <211> 2535 <212> DNA <213> HUMAN <400> 244 gaattccggg gtggtctgag ctggagccac gctttctgtt ggagggggca gctgaaggag 60 aacagcaaga catatccggc ggccctacgg actcggagag ctggagggac cccggagatc 120 tcaaagggac aggaaaggca gcagcagcca ccctctctcc cagtcaagtg gtcaccagca 180 ggactgaagg ggacagcccc tttgcagtgg ctcggcgagg agacccctgc accctagggt 240 cagtgcagga gcccagccgc tgagccatgc cgggtccccg ggcggcctgc agcgagccca 300 acccctgcac ccaggtagtc atgaacagcc acagctacaa tggcagcgtg gggcggccgc 360 tgggcagcgg gccgggcgcc ctgggacgag accctccgga ccctgaggcc ggccaccccc 420 cacaaccccc gcacagcccg ggcctccagg tggtagtggc caagagtgag ccagcccggc 480 cctcacccgg cagcccccgg gggcagcccc aggaccagga cgatgacgag gatgatgagg 540 aagatgaggc cggcaggcag agagcctcgg ggaaaccctc aaatgtgggc caccgcctgg 600 gccaccggcg ggcgctcttc gagaagcgga agcgcctcag cgactatgcc ctcattttcg 660 gcatgtttgg catcgtcgtc atggtgacgg agaccgagct gtcctggggg gtgtacacca 720 aggagtctct gtactcattc gcactcaaat gcctcatcag cctctccacg gccatcctgc 780 tgggtctcgt tgtcctctac catgcccggg agatccagct gttcatggtg gacaacgggg 840 ctgatgactg gcgcatcgcc atgacctgcg agcgcgtgtt cctcatctcg ctagagctgg 900 cagtgtgcgc cattcacccg gtgcccggcc actaccgctt cacgtggacg gcgcggctgg 960 ccttcacgta cgcgccctcg gtggccgagg ccgacgtgga cgtgctgctg tccatcccca 1020 tgttcctgcg cctctacctg ctgggccggg tgatgctact gcacagcaaa atcttcacgg 1080 acgcctcgag ccgcagcatc ggggccctca acaagatcac cttcaacacg cgcttcgtca 1140 tgaagacact catgaccatc tgccccggca ccgtgctgct ggtcttcagc atctcctcct 1200 ggatcatcgc agcctggacc gtgcgcgtct gcgagaggta ccacgacaag caggaagtga 1260 ccagcaactt cctgggggcc atgtggctga tttccatcac cttcctctcc attggctacg 1320 gcgacatggt gccccacacc tactgcggga agggtgtgtg cctgctcact ggcatcatgg 1380 gagctggctg taccgcgctc gtggtggctg tggtggctcg gaagctggag ctcaccaagg 1440 ctgagaagca cgtgcacaac ttcatgatgg acactcagct caccaagcgg gtaaaaaacg 1500 ccgctgctaa cgttctcagg gagacgtggc tcatctacaa acataccagg ctggtgaaga 1560 agccagacca agcccgggtt cggaaacacc agcgtaagtt cctccaagcc atccatcagg 1620 ctcagaagct ccggagtgtg aagatcgagc aagggaagct gaacgaccag gctaacacgc 1680 ttaccgacct agccaagacc cagaccgtca tgtacgacct tgtatcggag ctgcacgctc 1740 agcacgagga gctggaggcc cgcctggcca ccctggaaag ccgcttggat gcgctgggtg 1800 cctctctaca ggccctgcct ggcctcatcg cccaagccat acgcccaccc ccgcctcccc 1860 tgcctcccag gcccggcccc ggcccccaag accaggcagc ccggagctcc ccctgccggt 1920 ggacgcccgt ggccccctcg gactgcgggt gacggccctg cccgccacca gacccctaaa 1980 tcttggccat cgtgtggccg ccacctccgg gaagccttgt acagtggcgc ctcttggagt 2040 tcaagaagcc gacgctgagt caggctgagt ggactgaggc ctgccccgcc cagactgccc 2100 aggcagaggg cagggctgga ccatgggtga gggcagggga gcccggagct tcctctggtc 2160 acctggtccc ccgactctcc ccaggccccc ggtgggcatg gagcagcccg gggaggggtc 2220 cgtgctggtt ctgaataaag caggacccgc ctagtggctg cctgtgtgca tggctggaag 2280 gcactggtga tgtcccagga ggtagacctc cagccctggg taccaagatg aatgtgggaa 2340 tcagaaaaac ctgttcccat caccggccta gcctagaatc ctagcctaga agccctctct 2400 ccctctggct ggagctcagt agggacaact ctctagggac acctgtacca gccccacctg 2460 gcgctgagat ccctcagaca gcatggccca gccctggcca gaagcatcgc tccccttcaa 2520 ccaaccgcgt tgatg 2535 <210> 245 <211> 1537 <212> DNA <213> HUMAN <400> 245 cactcctgcc tccaccatgt ccatcagggt gacccagaag tcctacaagg tgtccacctc 60 tggcccccgg gccttcagca gccgctccta cacgagtggg cccggttccc gcatcagctc 120 ctcgagcttc tcccgagtgg gcagcagcaa ctttcgcggt ggcctgggcg gcggctatgg 180 tggggccagc ggcatgggag gcatcaccgc agttacggtc aaccagagcc tgctgagccc 240 ccttgtcctg gaggtggacc ccaacatcca ggccgtgcgc acccaggaga aggagcagat 300 caagaccctc aacaacaagt ttgcctcctt catagacaag gtacggttcc tggagcagca 360 gaacaagatg ctggagacca agtggagcct cctgcagcag cagaagacgg ctcgaagcaa 420 catggacaac atgttcgaga gctacatcaa caaccttagg cggcagctgg agactctggg 480 ccaggagaag ctgaagctgg aggcggagct tggcaacatg caggggctgg tggaggactt 540 caagaacaag tatgaggatg agatcaataa gcgtacagag atggagaacg aatttgtcct 600 catcaagaag gatgtggatg aagcttacat gaacaaggta gagctggagt ctcgcctgga 660 agggctgacc gacgagatca acttcctcag gcagctgtat gaagaggaga tccgggagct 720 gcagtcccag atctcggaca catctgtggt gctgtccatg gacaacagcc gctccctgga 780 catggacagc atcattgctg aggtcaaggc acagtacgag gatattgcca accgcagccg 840 ggctgaggct gagagcatgt accagatcaa gtatgaggag ctgcagagcc tggctgggaa 900 gcacggggat gacctgcggc gcacaaagac tgagatctct gagatgaacc ggaacatcag 960 ccggctccag gctgagattg agggcctcaa aggccagagg gcttccctgg aggccgccat 1020 tgcagatgcc gagcagcgtg gagagctggc cattaaggat gccaacgcca agttgtccga 1080 gctggaggcc gccctgcagc gggccaagca ggacatggcg cggcagctgc gtgagtacca 1140 ggagctgatg aacgtcaagc tggccctgga catcgagatc gccacctaca ggaagctgct 1200 ggagggcgag gagagccggc tggagtctgg gatgcagaac atgagtattc atacgaagac 1260 caccagcggc tatgcaggtg gtctgagctc ggcctatggg ggcctcacaa gccccggcct 1320 cagctacagc ctgggctcca gctttggctc tggcgcgggc tccagctcct tcagccgcac 1380 cagctcctcc agggccgtgg ttgtgaagaa gatcgagaca cgtgatggga agctggtgtc 1440 tgagtcctct gacgtcctgc ccaagtgaac agctgcggca gcccctccca gcctacccct 1500 cctgcgctgc cccagagcct gggaaggagg ccgctat 1537 <210> 246 <211> 545 <212> DNA <213> HUMAN <400> 246 atggccctgc tactggccct cagcctgctg gttctctgga cttccccagc cccaactctg 60 agtggcacca atgatgctga agactgctgc ctgtctgtga cccagaaacc catccctggg 120 tacatcgtga ggaacttcca ctaccttctc atcaaggatg gctgcagggt gcctgctgta 180 gtgttcacca cactgagggg ccgccagctc tgtgcacccc cagaccagcc ctgggtagaa 240 cgcatcatcc agagactgca gaggacctca gccaagatga agcgccgcag cagttaacct 300 atgaccgtgc agagggagcc cggagtccga gtcaagcatt gtgaattatt acctaacctg 360 gggaaccgag gaccagaagg aaggaccagg cttccagctc ctctgcacca gacctgacca 420 gccaggacag ggcctggggt gtgtgtgagt gtgagtgtga gcgagagggt gagtgtggtc 480 tagagtaaag ctgctccacc cccagattgc aatgctacca ataaagccgc ctggtgttta 540 caact 545 <210> 247 <211> 2534 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(2534) <223> N=any base <400> 247 ggcacgagct tgctcgcgga gagaggagct aggagcctcg gccaatggga gccggcgttg 60 ttggaggcca cggcggcgca gccccaaagc gagcgaagct agggtcgccg ccactgccgc 120 aggaggcgtg aggggataaa aacattcaga tggcagatca cagtttttca gatggggttc 180 cttcagattc cgtggaagct gctaaaaatg caagtaacac agaaaagctc acagatcagg 240 tgatgcagaa tcctcgagtt ctggcagctt tacaggagcg acttgacaat gtccctcaca 300 ccccttccag ctacatcgaa actttaccta aagcagtaaa aagaagaatt aatgcattga 360 aacaacttca ggtgagatgt gctcacatag aagccaagtt ctatgaagag gtacatgact 420 tggaaagaaa gtatgcagcg ctataccagc ctctctttga caagagaaga gaatttatca 480 ccggcgatgt tgaaccaaca gatgcggaat cggaatggca cagtgaaaat gaagaggaag 540 agaaattggc tggagacatg aaaagtaaag tagtcgtcac agaaaaagca gcggcaacgg 600 ctgaagagcc agatcccaaa ggaattccag agttctggtt taccatcttc agaaatgtgg 660 acatgctgag tgaattagtc caggaatatg atgaaccaat cttgaaacac ctgcaggata 720 ttaaagtgaa attttctgac cctggacagc ctatgtcttt tgtgttagag ttccactttg 780 aacccaacga ctactttacc aactcagtcc tgacaaaaac ctacaagatg aaatcagaac 840 cagataaggc tgatcccttt tcctttgaag gtcctgagat tgtggactgt gacgggtgta 900 ctattgactg gaagaaagga aagaatgtta ctgtcaaaac catcaagaaa aagcagaagc 960 ataagggtcg aggcactgtt agaacaatta cgaaacaagt acccaatgag tcctttttca 1020 acttcttcaa tccattgaaa gcatccgggg atggagaatc actggatgaa gattctgaat 1080 tcacattagc ctctgatttt gaaattggac actttttccg tgagcggata gtcccgcggg 1140 ctgtgctgta cttcactggg gaggccatag aagatgatga caattttgaa gaaggtgaag 1200 aaggagaaga ggaggaatta gaaggtgacg aggagggaga agacgaggat gatgcggaaa 1260 ttaaccccaa ggtgtaattt ttgtctgtta atcattcata cgtttctaga aggaacccag 1320 ccagccggcg gaatgcaagc agcagtagga agcggaggcg ggtgcctggc agaccggctg 1380 tcgggactcc aggcctgtgg gcggggcctc ggtccttgcc gcagcacaat cccgtggaca 1440 gagcttactc catctaactc gttttcaagt gcatgatttt cactttcact tttccttttt 1500 ccttattatt ttgattaact tgtacagtgg caactgaaat gcatttcaga aataggaggt 1560 ttcgtccagc accctctgca gccttggtgc ctgtagctct ggacttccct gggcctttcc 1620 ctgtgggagg gccctgtaga cacatcaggg tggggtgggg gtcacttggc aaaaagggcc 1680 gaggtctggt gatgtggttc ccaggatctt ggaacctctc ccacccctcc tgcagttgga 1740 ctgaattcta ccctttcatc cgaagaaacc cacttgctgt ttccagccgc tgaatctgct 1800 gagtgtgcag cctgcatcac ctgctgtatg ccgatcatct cagaaagggc tgtgtagagt 1860 agggccctgt tctccttagg atgttgcttc ttgatttttt ttttttttta ggggtgggtc 1920 agggttgtga cacaccagcc caggtgagag ctgctgcggg tcacctcata tttatttatc 1980 ccttcttgcc tgtgaggact gcggcttttc gctgtggctc gtccttaacg tttctgaacc 2040 accttggtgc cctgagcagg aagatgtgcc acttcctagc aggcgcaagg cctgtgcgga 2100 agaaacgccg ctccctgcca ccagggctga agatgcgagc ccgtcctcat gacgcaggcg 2160 ccaccctgct gccggagccg ggcttcggca tcttctccac tgagggactg ggctgggaag 2220 tcctgcgttt cagtggagcg tatgagcgtc aagtcctgct ttctcagtag ccccattgcg 2280 gggccccacc attcatcctg tctgaaggtc ctgggtttgg tgtgaccgct tggcggctgg 2340 tgggtggggt tttcaagtgg gtgacggcgc tctccggcaa ccggggatgg ccgtgtccgc 2400 actgaccagg cctgtggaga gtgctcggcc taaccttaga acacaattgt aactgaaaac 2460 agtgttttca atttgtacag aatagttaga atattctaat aaagtggtga aacattgaaa 2520 aaaaaanaaa aaaa 2534 <210> 248 <211> 417 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(417) <223> N=any base <400> 248 aattacattg atttattaga agcatttgta gtccttcatg gtttcagaaa atcaattgtt 60 cagacctttt tgaacatatc tgattgtgat attcatactg tgtaactctg aatttaaatc 120 aagttcagtg gaaattaaga tatgatcgta ttatttttta gtgtatgttt cgtatctgaa 180 tttttgatgc agttaaaaaa gccttaagaa aacgacaaaa aagctagagt gcagacaacc 240 taaaatctct attttaaaac atcattttcc tgaggccatg cagactcata tctaagtttt 300 tttcatttaa atagacttaa ttctaacaaa tacttacttt cataatggna aaacttttta 360 aaggtgggac agacatacta gttacgaaat ggaagttttc aatccacagg attccag 417 <210> 249 <211> 489 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(489) <223> N=any base <400> 249 tttttttttt ttatatttat atttatattt atatatatgt atatatatat atatgtnatg 60 tacaaaagac tttgagatat caggcaccat taaaccacat ttcccccctt ataaatgcaa 120 ctgttcaagt acactgggaa cagttttaag gtacacctgc agtacantag gagaagcatg 180 agtggataat ctaaacacag gatcataaca gtgatacgct gcaacacctc tgtgaattcc 240 attanccaag ttctgtcatt aaaacatngg aaaactactg gctcctcaaa ataaaaggtt 300 ttaggnaacc aaaaatcccc taagtagtga actgttttcc aagcagagct ccctaatggt 360 tttcaatttc ctgggcctac aaccaaangg ggaccccagt tggaagctgc cgtttgggaa 420 acgtgggcca ggcatcagat cancaacacg ggggggaatc cngagagggg cncattnttg 480 aagaaggng 489 <210> 250 <211> 429 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(429) <223> N=any base <400> 250 gacgtgaccc agggcagact ggtagcaaag cccccacgcc cagccaggag caccgccgag 60 gactccagca caccgaggga catgctgggc ctgcgccccc actgctcgcc ctggtgggnn 120 tgctctccct cgggtgcgtc ctctctcagg agtgcacgaa gttcaaggtc agcagctgcc 180 gggaatgcat cgagtcgggg cccggctgca cctggtncag aagctgggag cggctttggg 240 tcctccagcc cacgccaccg cggcgaagca agtccccgga gangaagccg ggtggctccc 300 gtctgtcctc ggactgagca gggtggccaa ggcccaggtt ggaaactacc ttggtcaggc 360 tgggtttttt ncctcccctt tctggaggtt ttcaagctcc tcttgaaata aacacctttt 420 caagtgaga 429 <210> 251 <211> 1761 <212> DNA <213> HUMAN <400> 251 ttgccgatcc gccgcccgtc cacacccgcc gccagctcac catggatgat gatatcgccg 60 cgctcgtcgt cgacaacggc tccggcatgt gcaaggccgg cttcgcgggc gacgatgccc 120 cccgggccgt cttcccctcc atcgtggggc gccccaggca ccagggcgtg atggtgggca 180 tgggtcagaa ggattcctat gtgggcgacg aggcccagag caagagaggc atcctcaccc 240 tgaagtaccc catcgagcac ggcatcgtca ccaactggga cgacatggag aaaatctggc 300 accacacctt ctacaatgag ctgcgtgtgg ctcccgagga gcaccccgtg ctgctgaccg 360 aggcccccct gaaccccaag gccaaccgcg agaagatgac ccagatcatg tttgagacct 420 tcaacacccc agccatgtac gttgctatcc aggctgtgct atccctgtac gcctctggcc 480 gtaccactgg catcgtgatg gactccggtg acggggtcac ccacactgtg cccatctacg 540 aggggtatgc cctcccccat gccatcctgc gtctggacct ggctggccgg gacctgactg 600 actacctcat gaagatcctc accgagcgcg gctacagctt caccaccacg gccgagcggg 660 aaatcgtgcg tgacattaag gagaagctgt gctacgtcgc cctggacttc gagcaagaga 720 tggccacggc tgcttccagc tcctccctgg agaagagcta cgagctgcct gacggccagg 780 tcatcaccat tggcaatgag cggttccgct gccctgaggc actcttccag ccttccttcc 840 tgggcatgga gtcctgtggc atccacgaaa ctaccttcaa ctccatcatg aagtgtgacg 900 tggacatccg caaagacctg tacgccaaca cagtgctgtc tggcggcacc accatgtacc 960 ctggcattgc cgacaggatg cagaaggaga tcactgccct ggcacccagc acaatgaaga 1020 tcaagatcat tgctcctcct gagcgcaagt actccgtgtg gatcggcggc tccatcctgg 1080 cctcgctgtc caccttccag cagatgtgga tcagcaagca ggagtatgac gagtccggcc 1140 cctccatcgt ccaccgcaaa tgcttctagg cggactatga cttagttgcg ttacaccctt 1200 tcttgacaaa acctaacttg cgcagaaaac aagatgagat tggcatggct ttatttgttt 1260 tttttgtttt gttttggttt tttttttttt tttggcttga ctcaggattt aaaaactgga 1320 acggtgaagg tgacagcagt cggttggagc gagcatcccc caaagttcac aatgtggccg 1380 aggactttga ttgcacattg ttgttttttt aatagtcatt ccaaatatga gatgcattgt 1440 tacaggaagt cccttgccat cctaaaagcc accccacttc tctctaagga gaatggccca 1500 gtcctctccc aagtccacac aggggaggtg atagcattgc tttcgtgtaa attatgtaat 1560 gcaaaatttt tttaatcttc gccttaatac ttttttattt tgttttattt tgaatgatga 1620 gccttcgtgc ccccccttcc ccctttttgt cccccaactt gagatgtatg aaggcttttg 1680 gtctccctgg gagtgggtgg aggcagccag ggcttacctg tacactgact tgagaccagt 1740 tgaataaaag tgcacacctt a 1761 <210> 252 <211> 2300 <212> DNA <213> HUMAN <400> 252 tatattccgg gggtctgcgc ggccgaggac ccctgggtgc gctgctctca gctgccgggt 60 ccgactcgcc tcactcagct cccctcctgc ctcctgaagg gcagcttcgc cgacgcttgg 120 cgggaaaaag aagggagggg agggatcctg agtcgcagta taaaagaagc ttttcgggcg 180 tttttttctg actcgctgta gtaattccag cgagagacag agggagtgag cggacggttg 240 gaagagccgt gtgtgcagag ccgcgctccg gggcgaccta agaaggcagc tctggagtga 300 gaggggcttt gcctccgagc ctgccgccca ctctccccaa ccctgcgact gacccaacat 360 cagcggccgc aaccctcgcc gccgctggga aactttgccc attgcagcgg gcagacactt 420 ctcactggaa cttacaatct gcgagccagg acaggactcc ccaggctccg gggagggaat 480 ttttgtctat ttggggacag tgttctctgc ctctgcccgc gatcagctct cctgaaaaga 540 gctcctcgag ctgtttgaag gctggatttc ctttgggcgt tggaaacccc gcagacagcc 600 acgacgatgc ccctcaacgt gaacttcacc aacaggaact atgacctcga ctacgactcc 660 gtacagccct atttcatctg cgacgaggaa gagaatttct atcaccagca acagcagagc 720 gagctgcagc cgcccgcgcc cagtgaggat atctggaaga aattcgagct gcttcccacc 780 ccgcccctgt ccccgagccg ccgctccggg ctctgctctc catcctatgt tgcggtcgct 840 acgtccttct ccccaaggga agacgatgac ggcggcggtg gcaacttctc caccgccgat 900 cagctggaga tgatgaccga gttacttgga ggagacatgg tgaaccagag cttcatctgc 960 gatcctgacg acgagacctt catcaagaac atcatcatcc aggactgtat gtggagcggt 1020 ttctcagccg ctgccaagct ggtctcggag aagctggcct cctaccaggc tgcgcgcaaa 1080 gacagcacca gcctgagccc cgcccgcggg cacagcgtct gctccacctc cagcctgtac 1140 ctgcaggacc tcaccgccgc cgcgtccgag tgcattgacc cctcagtggt ctttccctac 1200 ccgctcaacg acagcagctc gcccaaatcc tgtacctcgt ccgattccac ggccttctct 1260 ccttcctcgg actcgctgct gtcctccgag tcctccccac gggccagccc tgagccccta 1320 gtgctgcatg aggagacacc gcccaccacc agcagcgact ctgaagaaga gcaagaagat 1380 gaggaagaaa ttgatgtggt gtctgtggag aagaggcaaa cccctgccaa gaggtcggag 1440 tcgggctcat ctccatcccg aggccacagc aaacctccgc acagcccact ggtcctcaag 1500 aggtgccacg tctccactca ccagcacaac tacgccgcac ccccctccac aaggaaggac 1560 tatccagctg ccaagagggc caagttggac agtggcaggg tcctgaagca gatcagcaac 1620 aaccgcaagt gctccagccc caggtcctca gacacggagg aaaacgacaa gaggcggaca 1680 cacaacgtct tggaacgtca gaggaggaac gagctgaagc gcagcttttt tgccctgcgt 1740 gaccagatcc ctgaattgga aaacaacgaa aaggccccca aggtagtgat cctcaaaaaa 1800 gccaccgcct acatcctgtc cattcaagca gacgagcaca agctcacctc tgaaaaggac 1860 ttattgagga aacgacgaga acagttgaaa cacaaactcg aacagcttcg aaactctggt 1920 gcataaactg acctaactcg aggaggagct ggaatctctc gtgagagtaa ggagaacggt 1980 tccttctgac agaactgatg cgctggaatt aaaatgcatg ctcaaagcct aacctcacaa 2040 ccttggctgg ggctttggga ctgtaagctt cagccataat tttaactgcc tcaaacttaa 2100 atagtataaa agaacttttt ttatgcttcc catctttttt ctttttcctt ttaacagatt 2160 tgtatttaat tgttttttta aaaaaatctt aaaatctatc caattttccc atgtaaatag 2220 ggccttgaaa tgtaaataac tttaataaaa cgtttataac agttacaaaa gattttaaga 2280 catgtaccat aatttttttt 2300 <210> 253 <211> 702 <212> DNA <213> HUMAN <400> 253 ttccggtacc tgtgagtcag ctaggggagg gcagctctca cccaggctga tagttcggtg 60 acctggcttt atctactgga tgagttccgc tgggagatgg aacatagcac gtttctctct 120 ggcctggtac tggctaccct tctctcgcaa gtgagcccct tcaagatacc tatagaggaa 180 cttgaggaca gagtgtttgt gaattgcaat accagcatca catgggtaga gggaacggtg 240 ggaacactgc tctcagacat tacaagactg gacctgggaa aacgcatcct ggacccacga 300 ggaatatata ggtgtaatgg gacagatata tacaaggaca aagaatctac cgtgcaagtt 360 cattatcgaa tgtgccagag ctgtgtggag ctggatccag ccaccgtggc tggcatcatt 420 gtcactgatg tcattgccac tctgctcctt gctttgggag tcttctgctt tgctggacat 480 gagactggaa ggctgtctgg ggctgccgac acacaagctc tgttgaggaa tgaccaggtc 540 tatcagcccc tccgagatcg agatgatgct cagtacagcc accttggagg aaactgggct 600 cggaacaagt gaacctgaga ctggtggctt ctagaagcag ccattaccaa ctgtaccttc 660 ccttcttgct cagccaataa atatatcctc tttcactcaa aa 702 <210> 254 <211> 1536 <212> DNA <213> HUMAN <400> 254 gggggggggg ggaccacttg gcctgcctcc gtcccgccgc gccacttggc ctgcctccgt 60 cccgccgcgc cacttcgcct gcctccgtcc cccgcccgcc gcgccatgcc tgtggccggc 120 tcggagctgc cgcgccggcc cttgcccccc gccgcacagg agcgggacgc cgagccgcgt 180 ccgccgcacg gggagctgca gtacctgggg cagatccaac acatcctccg ctgcggcgtc 240 aggaaggacg accgcacggg caccggcacc ctgtcggtat tcggcatgca ggcgcgctac 300 agcctgagag atgaattccc tctgctgaca accaaacgtg tgttctggaa gggtgttttg 360 gaggagttgc tgtggtttat caagggatcc acaaatgcta aagagctgtc ttccaaggga 420 gtgaaaatct gggatgccaa tggatcccga gactttttgg acagcctggg attctccacc 480 agagaagaag gggacttggg cccagtttat ggcttccagt ggaggcattt tggggcagaa 540 tacagagata tggaatcaga ttattcagga cagggagttg accaactgca aagagtgatt 600 gacaccatca aaaccaaccc tgacgacaga agaatcatca tgtgcgcttg gaatccaaga 660 gatcttcctc tgatggcgct gcctccatgc catgccctct gccagttcta tgtggtgaac 720 agtgagctgt cctgccagct gtaccagaga tcgggagaca tgggcctcgg tgtgcctttc 780 aacatcgcca gctacgccct gctcacgtac atgattgcgc acatcacggg cctgaagcca 840 ggtgacttta tacacacttt gggagatgca catatttacc tgaatcacat cgagccactg 900 aaaattcagc ttcagcgaga acccagacct ttcccaaagc tcaggattct tcgaaaagtt 960 gagaaaattg atgacttcaa agctgaagac tttcagattg aagggtacaa tccgcatcca 1020 actattaaaa tggaaatggc tgtttagggt gctttcaaag gagcttgaag gatattgtca 1080 gtctttaggg gttgggctgg atgccgaggt aaaagttctt tttgctctaa aagaaaaagg 1140 aactaggtca aaaatctgtc cgtgacctat cagttattaa tttttaagga tgttgccact 1200 ggcaaatgta actgtgccag ttctttccat aataaaaggc tttgagttaa ctcactgagg 1260 gtatctgaca atgctgaggt tatgaacaaa gtgaggagaa tgaaatgtat gtgctcttag 1320 caaaaacatg tatgtgcatt tcaatcccac gtacttataa agaaggttgg tgaatttcac 1380 aagctatttt tggaatattt ttagaatatt ttaagaattt cacaagctat tccctcaaat 1440 ctgagggagc tgagtaacac catcgatcat gatgtagagt gtggttatga actttatagt 1500 tgttttatat gttgctataa taaagaagtg ttctgc 1536 <210> 255 <211> 12072 <212> DNA <213> HUMAN <400> 255 ctacacactt cttgaaggca aaggcaatgc tgaagtcacc tttcatgttc aaatcatatt 60 aaaaagttag caagatgtaa ttatcagtgt actatgtaaa tctttgtgaa tgatcaataa 120 ttacatattt tcattatata tattttagta gataatattt atatacattc aacattctaa 180 atatagaaag tttacagaga aaaataaagc ctttttttcc aatcctgtcc tccacctctg 240 catcccattc ttcttcacag aggcaactga ttcaagtcat tacatagtta ttgagtgtta 300 actacaacta tgttaagtac agctatatat gttagatgcc gtagccacag aaatcagttt 360 acaatctaat gcagtggata cagcatgtat acatataata taaggttgct acaaatgcta 420 tctgaggtag agctgtttga aagaatacta atacttaaat gtttaattca actgacttga 480 ttgacaactg attagctgag tggaaaagat ggatgagaaa gattgtgaga cttaattggc 540 tggtggtatg gtgatatgat tgacaataac tgctaagtca gagagggata tattaaggag 600 gagaagaaaa gcaacaaatc tggttttgat gtgttcactt tgttataatt attgattatt 660 tactgaatat gaatatttat ctttgttttt gagtcaataa atataccttt gtaaagacag 720 aattaaagta ttagtatttc tttcaaactg gaggcatttc tcccactaac atatttcatc 780 aaaacttata ataagcttgg ttccagagga agaaatgagg gataaccaaa aatagagaca 840 ttaataatag tgtaacgccc agtgataaat ctcaataggc agtgatgaca gacatgtttt 900 cccaaacaca aggatgctgt aagggccaaa cagaaatgat ggcccctccc cagcacctca 960 ttttgcccct tccttcagct atgcctctac tctcctttag atacaaggga ggtggatttt 1020 tctcttctct gagatagctt gatggaacca caggaacaat gaagtgggct cctggctctt 1080 ttctctgtgg cagatggggt gccatgccca ccttcagaca aagggaagat tgagctcaaa 1140 agctccctga gaagtgagag cctatgaaca tggttgacac agagggacag gaatgtattt 1200 ccagggtcat tcattcctgg gaatagtgaa ctgggacatg ggggaagtca gtctcctcct 1260 gccacagcca cagattaaaa ataataatgt taactgatcc ctaggctaaa ataatagtgt 1320 taactgatcc ctaagctaag aaagttcttt tggtaattca ggtgatggca gcaggaccca 1380 tcttaaggat agactaggtt tgcttagttc gaggtcatat ctgtttgctc tcagccatgt 1440 actggaagaa gttgcatcac acagcctcca ggactgccct cctcctcaca gcaatggata 1500 atgcttcact agcctttgca gataattttg gatcagagaa aaaaccttga gctgggccaa 1560 aaaggaggag cttcaacctg tgtgcaaaat ctgggaacct gacagtatag gttgggggcc 1620 aggatgagga aaaaggaacg ggaaagacct gcccaccctt ctggtaagga ggccccgtga 1680 tcagctccag ccatttgcag tcctggctat cccaggagct tacataaagg gacaattgga 1740 gcctgagagg tgacagtgct gacactacaa ggctcggagc tccgggcact cagacatcat 1800 gagttggtcc ttgcaccccc ggaatttaat tctctacttc tatgctcttt tatttctctc 1860 ttcaacatgt gtagcagtaa gtgtgctctt cacaaaacgt tgtttaaaat ggaaagctgg 1920 aaaataaaac agataataaa ctagtgaaat tttcgtattt tttctctttt agtatgttgc 1980 taccagagac aactgctgca tcttagatga aagattcgta agtagttttt atgtttctcc 2040 ctttgtgtgt gaactggaga ggggcagagg aatagaaata attccctcat aaatatcatc 2100 tggcacttgt aactttttaa aaacatagtc taggttttac ctatttttct taatagattt 2160 taagagtagc atctgtctac atttttaatc actgttatat tttcagggta gttattgtcc 2220 aactacctgt ggcattgcag atttcctgtc tacttatcaa accaaagtag acaaggatct 2280 acagtctttg gaagacatct tacatcaagt tgaaaacaaa acatcagaag tcaaacagct 2340 gataaaagca atccaactca cttataatcc tgatgaatca tcaaaaccaa gtgagaaaat 2400 aaagactact gaccaaaaaa taataataat aatctgtgaa gttcttttgc tgttgtttta 2460 gttgttctat ttgcttaagg atttttatgt ctctgatcct atattacaga tatgatagac 2520 gctgctactt tgaagtccag gataatgtta gaagaaatta tgaaatatga agcatcgatt 2580 ttaacacatg actcaagtat tcggtaagga tttttgtttt aatttgctct gcaagactga 2640 tttagttttt atttaatatt ctatacttga gtgaaagtaa tttttaatgt gttttcccca 2700 tttataatat cccagtgaca ttatgcctga ttatgttgag catagtagag atagaagttt 2760 ttagtgcaat ataaattata ctgggttata attgcttatt aataatcaca ttgaagaaag 2820 atgttctaga tgtcttcaaa tgctagtttg accatattta tcaaaaattt tttccccatc 2880 ccccatttat cttacaacat aaaatcaatc tcataggaat ttgggtgttg aaaataaaat 2940 cctctttata aaaatgctga caaattggtg gttaaaaaaa ttagcaagca gaggcatagt 3000 aaggattttg gctcctaaag taaattatat tgaatgtgga gcaggaagaa acatgtcttg 3060 agagactaag tgtggcaaat attgcaaagc tcatattgat cattgcagaa tgaacctgca 3120 tagtctcttc ccttcatttg gaagtgaatg tctctgttaa agcttctcag ggactcataa 3180 actttctgaa cataaggtct cagatacagt tttaatattt ttccccaatt tttttttctg 3240 aatttttctc aaagcagctt gagaaattga gataaatagt agctagggag aagtggccca 3300 ggaaagattt ctcctctttt tgctatcaga gggcccttgt tattattgtt attattatta 3360 cttgcattat tattgtccat cattgaagtt gaaggaggtt attgtacaga aattgcctaa 3420 gacaaggtag agggaaaacg tggacaaata gtttgtctac ccttttttac ttcaaagaaa 3480 gaacggttta tgcattgtag acagttttct atcatttttg gatatttgca agccaccctg 3540 taagtaacta caaaaggagg gtttttactt cccccagtcc attcccaaag ctatgtaacc 3600 agaagcatta aagaagaaag gggaagtatc tgttgtttta ttttacatac aataacgttc 3660 cagatcatgt ccctgtgtaa gttatatttt agattgaagc ttatatgtat agcctcagta 3720 gatccacaag tgaaaggtat actccttcag cacatgtgaa ttactgaact gagcttttcc 3780 tgcttctaaa gcatcagggg gtgttcctat taaccagtct cgccactctt gcaggttgct 3840 atctgctgtc ccttatgcat aaagtaaaaa gcaaaatgtc aatgacattt gcttattgac 3900 aaggactttg ttatttgtgt tgggagttga gacaatatgc cccattctaa gtaaaaagat 3960 tcaggtccac attgtattcc tgttttaatt gattttttga tttgtttttc tttttcaaaa 4020 agtttataat tttaattcat gttaatttag taatataatt ttacattttc ctcaagaatg 4080 gaataattta tcagaaagca cttcttaaga aaatacttag cagtttccaa agaaaatata 4140 aaattactct tctgaaagga atacttattt ttgtcttctt atttttgtta tcttatgttt 4200 ctgtttgtag atatttgcag gaaatatata attcaaataa tcaaaagatt gttaacctga 4260 aagagaaggt agcccagctt gaagcacagt gccaggaacc ttgcaaagac acggtgcaaa 4320 tccatgatat cactgggaaa ggtaactgat gaaggttata ttgggattag gttcatcaaa 4380 gtaagtaatg taaaggagaa agtatgtact ggaaagtata ggaatagttt agaaagtggc 4440 tacccattaa gtctaagaat ttcagttgtc tagacctttc ttgaatagct aaaaaaaaca 4500 gtttaaaagg aatgctgatg tgaaaagtaa gaaaattatt cttggaaaat gaatagttta 4560 ctacatgtta aaagctattt ttcaaggctg gcacagtctt acctgcattt caaaccacag 4620 taaaagtcga ttctccttct ctagattgtc aagacattgc caataaggga gctaaacaga 4680 gcgggcttta ctttattaaa cctctgaaag ctaaccagca attcttagtc tactgtgaaa 4740 tcgatgggtc tggaaatgga tggactgtgt ttcagaaggt aattttttcc ccaccatgtg 4800 tatttaataa attcctacat tgtttctgcc atatggcaga tacttttcta agcaccttgt 4860 gaaccgtagc tcatttaatc cttgcaatag ccctaagagg aaggtacttc tgttactcct 4920 atttacagaa aaggaaactg aggcacacaa ggttaaataa cttgcccaag accacataac 4980 taataagcaa cagagtcagc atttgaacct aggcagtata gtttcagagt ttgtgacttg 5040 actctatatt gtactggcac tgactttgta gattcatggt ggcacataat catagtacca 5100 cagtgacaaa taaaaagaag gaaactcttt tgtcaggtag gtcaagacct gaggtttccc 5160 atcacaagat gaggaagccc aacaccaccc cccaccaccc caccaccatc accacccttt 5220 cacacaccag aggatacact tgggctgctc caagacaagg aacctgtgtt gcatctgcca 5280 cttgctgata cccactagga atcttggctc ctttactttc tgtttacctc ccaccactgt 5340 tataactgtt tctacagggg gcgctcagag ggaatgaatg gtggaagcat tagttgccag 5400 acaccgattg agcaatgggt tccatcataa gtgtaagaat cagtaatatc cagctagagt 5460 tctgaagtcg tctaggtgtc tttttaatat taccactcat ttagaattta tgatgtgcca 5520 gaaaccctct taagtatttc tcttatattc tctctcatga tccttgcagc aaccctaaga 5580 agtaaccatc atttttccta tttgatacat gaggaaactg aggtagcttg gccaagatca 5640 cttagttggg agttgataga accagtgctc tgtatttttg acaaaatgtt gacagcattc 5700 tctttacatg cattgatagt ctattttctc cttttgctct tgcaaatgtg taattagaga 5760 cttgatggca gtgtagattt caagaaaaac tggattcaat ataaagaagg atttggacat 5820 ctgtctccta ctggcacaac agaattttgg ctgggaaatg agaagattca tttgataagc 5880 acacagtctg ccatcccata tgcattaaga gtggaactgg aagactggaa tggcagaacc 5940 aggtactgtt ttgaaatgac ttccaacttt ttattgtaaa gattgcctgg aatgtgcact 6000 ttccaactat caatagacaa tggcaaatgc agcctgacaa atgcaaacag cacatccagc 6060 caccattttc tccaggagtc tgtttggttc ttgggcaatc caaaaaggta aattctattc 6120 aggatgaatc taagtgtatt ggtacaatct aattaccctg gaaccattca gagtaatagc 6180 taattactga acttttaatc agtcccagga attgagcata aaattataat tttatctagt 6240 ctaaattact atttcatgaa gcaggtatta ttattaatcc cattttatag attaacttgc 6300 tcaaagtcac attgctgata agtggtagag gtagaattca gactcaagta gtttaacttt 6360 agagcctgtc ctcttaacaa ctatcctggt tgaaaagcaa atacagcctc ttcagacttc 6420 tcagtgcctt gatggccatt tattctgtca aatcatgagc taccctaaaa gtaaaccagc 6480 tagctctttt gatgatctag aggcttcttt ttgcttgaga tatttgaagg ttttaagcat 6540 tgttacctaa ttaaaatgca gaaaaatatc caaccctctt gttatgttta aggaatagtg 6600 aaatatattg tcttcaaaca catggacttt tttttattgc ttggttggtt tttaatccag 6660 aaagtgctat agtcagtaga ccttcttcta ggaaaggacc ttccatttcc cagccactgg 6720 agattagaaa ataagctaaa tattttctgg aaatttctgt tcattcatta aggcccatcc 6780 tttcccccac tctatagaag tgttgtccac ttgcacaatt ttttccagga aagaatctct 6840 ctaactcctt cagctcacat gctttggacc acacagggaa gactttgatt gtgtaatgcc 6900 ctcagaagct ctccttcttg ccactaccac actgatttga ggaagaaaat ccctttagca 6960 cctaaccctt caggtgctat gagtggctaa tggaactgta cctccttcaa gttttgtgca 7020 ataattaagg gtcactcact gtcagatact ttctgtgatc tatgataatg tgtgtgcaac 7080 acataacatt tcaataaaag tagaaaatat gaaattagag tcatctacac atctggattt 7140 gatcttagaa tgaaacaagc aaaaaagcat ccaagtgagt gcaattatta gttttcagag 7200 atgcttcaaa ggcttctagg cccatcccgg gaagtgttaa tgagctgtgg actggttcac 7260 atatctattg cctcttgcca gatttgcaaa aaacttcact caatgagcaa atttcagcct 7320 taagaaacaa agtcaaaaat tccaaggaag catcctacga aagagggaac ttctgagatc 7380 cctgaggagg gtcagcatgt gatggttgta tttccttctt ctcagtactg cagactatgc 7440 catgttcaag gtgggacctg aagctgacaa gtaccgccta acatatgcct acttcgctgg 7500 tggggatgct ggagatgcct ttgatggctt tgattttggc gatgatccta gtgacaagtt 7560 tttcacatcc cataatggca tgcagttcag tacctgggac aatgacaatg ataagtttga 7620 aggcaactgt gctgaacagg atggatctgg ttggtggatg aacaagtgtc acgctggcca 7680 tctcaatgga gtttattacc aaggtatgtt ttcctttctt agattccaag ttaatgtata 7740 gtgtatacta ttttcataaa aaataataaa tagatatgaa gaaatgaaga ataatttata 7800 aagatagtag ggattttatc atgttcttta tttcaactaa gttctttgaa actggaagtg 7860 gataatacca agttcatgcc taaaattagc ccttctaaag aaatccacct gctgcaaaat 7920 atccagtagt ttggcattat atgtgaaact atcaccatca tagctggcac tgtgggttgt 7980 gggatctcct ttagacatac aacataaatg atctggatgg attaacatta ctacatggat 8040 gcttgttgac acattaacct ggcttcccat gagctttgtg tcagatacac gcagtgaaca 8100 ggtgtttgga ggaacagaat aaagagaagg caagcactgg taagggcagg ggtttgtgaa 8160 agcttgagag aagagaccag tctgaggaca gtagacactt attttaggat gggggttgga 8220 tgaggaggct atagtttgct ataagcttgg aatggtttgg aacactggtt tcactcacct 8280 acccagcagt tatgtgtggg gaagccttac cgatgctaaa ggatccatgt tacaataatg 8340 gcattatttg gaaatcccag tggtattcca tgaataaaac cactatgaag ataatcccac 8400 tcaacagact ctccgttgga gaaggacagc aacaccaccc tgggaaagcc aaacagtcag 8460 accagacctg tttagcatca gtaggacttc cctaccatat ctgctgggta gatgagtgaa 8520 accagtgttc caaaccactc cgggcttgta gcaaaccata gtctcctcat ctaccaagat 8580 gagcaacctt acctcctgat gtcctagcca atcaccaact aggaaacttt gcacagttta 8640 tttaaagtaa cagtttgatt ttcacaatat ttttaaattg gagaaacata acttatcttt 8700 gcactcacaa accacataat gagaagaaac tctaagggaa aatgcttgat ctgtgtgacc 8760 cggggcgcca tgccagagct gtagttcatg ccagtgttgt gctctgacaa gccttttaca 8820 gaattacatg agatctgctt ccctaggaca aggagaaggc aaatcaacag aggctgcact 8880 ttaaaatgga gacataaaat aacatgccag aaccatttcc taaagctcct caatcaacca 8940 acaaaattgt gctttcaaat aacctgagtt gacctcatca ggaattttgt ggctccttct 9000 cttctaacct gcctgaagaa agatggtcca cagcagctga gtccgggatg gataagctta 9060 gggacagagg ccaattaggg aactttgggt ttctagccct actagtagtg aataaattta 9120 aagtgtggat gtgactatga gtcacagcac agatgttgtt taataatatg tttattttat 9180 aaattgatat tttaggaatc tttggagata ttttcagtta gcagataata ctataaattt 9240 tatgtaactg gcaatgcact tcgtaataga cagctcttca tagacttgca gaggtaaaaa 9300 gattccagaa taatgatatg tacatctacg acttgtttta ggtggcactt actcaaaagc 9360 atctactcct aatggttatg ataatggcat tatttgggcc acttggaaaa cccggtggta 9420 ttccatgaag aaaaccacta tgaagataat cccattcaac agactcacaa ttggagaagg 9480 acagcaacac cacctggggg gagccaaaca ggtcagacca gagcaccctg cggaaacaga 9540 atatgactca ctttaccctg aggatgattt gtagaaaatt aactgctaac ttctattgac 9600 ccacaaagtt tcagaaattc tctgaaagtt tcttcctttt ttctcttact atatttattg 9660 atttcaagtc ttctattaag gacatttagc cttcaatgga aattaaaact catttaggac 9720 tgtatttcca aattactgat atcagagtta tttaaaaatt gtttatttga ggagataaca 9780 tttcaacttt gttcctaaat atataataat aaaatgattg actttatttg catttttatg 9840 accacttgtc atttattttg tcttcgtaaa ttattttcat tatatcaaat attttagtat 9900 gtacttaata aaataggaga acattttaga gtttcaaatt cccaggtatt ttccttgttt 9960 attaccccta aatcattcct atttaattct tctttttaaa tggagaaaat tatgtctttt 10020 taatatggtt tttgttttgt tatatattca caggctggag acgtttaaaa gaccgtttca 10080 aaagagattt acttttttaa aggactttat ctgaacagag agatataata tttttcctat 10140 tggacaatgg acttgcaaag cttcacttca ttttaagagc aaaagacccc atgttgaaaa 10200 ctccataaca gttttatgct gatgataatt tatctacatg catttcaata aaccttttgt 10260 ttcctaagac tagatacatg gtacctttat tgaccattaa aaaaccacca ctttttgcca 10320 atttaccaat tacaattggg caaccatcag tagtaattga gtcctcattt tatgctaaat 10380 gttatgccta actctttggg agttacaaag gaaatagcaa ttatggcttt tgccctctag 10440 gagatacagg acaaatacag gaaaatacag caacccaaac tgacaatact ctatacaaga 10500 acataatcac taagcaggag tcacagccac acaaccaaga tgcatagtat ccaaagtgca 10560 gctgtgtgca aattaacagt cctaactggt atagagcacc tagtccagtg acctgctggg 10620 taaactgtgg atgatggttg caaaagacta atttaaaaaa taactaccaa gaggccctgt 10680 ctgtacctaa cgccctattt ttgcaatggc tatatggcaa gaaagctggt aaactatttg 10740 tctttcagga ccttttgaag tagtttgtat aacttcttaa aagttgtgat tccagataac 10800 cagctgtaac acagctgaga gacttttaat cagacaaagt aattcctctc actaaacttt 10860 acccaaaaac taaatctcta atatggcaaa aatggctaga cacccatttt cacattccca 10920 tctgtcacca attggttaat ctttcctgat ggtacaggaa agctcagcta ctgatttttg 10980 tgatttagaa ctgtatgtca gacatccatg tttgtaaaac tacacatccc taatgtgtgc 11040 catagagttt aacacaagtc ctgtgaattt cttcactgtt gaaaattatt ttaaacaaaa 11100 tagaagctgt agtagccctt tctgtgtgca ccttaccaac tttctgtaaa ctcaaaactt 11160 aacatattta ctaagccaca agaaatttga tttctattca aggtggccaa attatttgtg 11220 taatagaaaa ctgaaaatct aatattaaaa atatggaact tctaatatat ttttatattt 11280 agttatagtt tcagatatat atcatattgg tattcactaa tctgggaagg gaagggctac 11340 tgcagcttta catgcaattt attaaaatga ttgtaaaata gcttgtatag tgtaaaataa 11400 gaatgatttt tagatgagat tgttttatca tgacatgtta tatatttttt gtaggggtca 11460 aagaaatgct gatggataac ctatatgatt tatagtttgt acatgcattc atacaggcag 11520 cgatggtctc agaaaccaaa cagtttgctc taggggaaga gggagatgga gactggtcct 11580 gtgtgcagtg aaggttgctg aggctctgac ccagtgagat tacagaggaa gttatcctct 11640 gcctcccatt ctgaccaccc ttctcattcc aacagtgagt ctgtcagcgc aggtttagtt 11700 tactcaatct ccccttgcac taaagtatgt aaagtatgta aacaggagac aggaaggtgg 11760 tgcttacatc cttaaaggca ccatctaata gcgggttact ttcacataca gccctccccc 11820 agcagttgaa tgacaacaga agcttcagaa gtttggcaat agtttgcata gaggtaccag 11880 caatatgtaa atagtgcaga atctcatagg ttgccaataa tacactaatt cctttctatc 11940 ctacaacaag agtttatttc caaataaaat gaggacatgt ttttgttttc tttgaatgct 12000 ttttgaatgt tatttgttat tttcagtatt ttggagaaat tatttaataa aaaaacaatc 12060 atttgctttt tg 12072 <210> 256 <211> 3148 <212> DNA <213> HUMAN <400> 256 gaattcccgc ggagcagcgt gcgcggggcc ccgggagacg gcggcggtag cggcgcgggc 60 agagcaagga cgcggcggat cccactcgca cagcagcgca ctcggtgccc cgcgcagggt 120 cgcgatgctg cccggtttgg cactgctcct gctggccgcc tggacggctc gggcgctgga 180 ggtacccact gatggtaatg ctggcctgct ggctgaaccc cagattgcca tgttctgtgg 240 cagactgaac atgcacatga atgtccagaa tgggaagtgg gattcagatc catcagggac 300 caaaacctgc attgatacca aggaaggcat cctgcagtat tgccaagaag tctaccctga 360 actgcagatc accaatgtgg tagaagccaa ccaaccagtg accatccaga actggtgcaa 420 gcggggccgc aagcagtgca agacccatcc ccactttgtg attccctacc gctgcttagt 480 tggtgagttt gtaagtgatg cccttctcgt tcctgacaag tgcaaattct tacaccagga 540 gaggatggat gtttgcgaaa ctcatcttca ctggcacacc gtcgccaaag agacatgcag 600 tgagaagagt accaacttgc atgactacgg catgttgctg ccctgcggaa ttgacaagtt 660 ccgaggggta gagtttgtgt gttgcccact ggctgaagaa agtgacaatg tggattctgc 720 tgatgcggag gaggatgact cggatgtctg gtggggcgga gcagacacag actatgcaga 780 tgggagtgaa gacaaagtag tagaagtagc agaggaggaa gaagtggctg aggtggaaga 840 agaagaagcc gatgatgacg aggacgatga ggatggtgat gaggtagagg aagaggctga 900 ggaaccctac gaagaagcca cagagagaac caccagcatt gccaccacca ccaccaccac 960 cacagagtct gtggaagagg tggttcgaga ggtgtgctct gaacaagccg agacggggcc 1020 gtgccgagca atgatctccc gctggtactt tgatgtgact gaagggaagt gtgccccatt 1080 cttttacggc ggatgtggcg gcaaccggaa caactttgac acagaagagt actgcatggc 1140 cgtgtgtggc agcgccattc ctacaacagc agccagtacc cctgatgccg ttgacaagta 1200 tctcgagaca cctggggatg agaatgaaca tgcccatttc cagaaagcca aagagaggct 1260 tgaggccaag caccgagaga gaatgtccca ggtcatgaga gaatgggaag aggcagaacg 1320 tcaagcaaag aacttgccta aagctgataa gaaggcagtt atccagcatt tccaggagaa 1380 agtggaatct ttggaacagg aagcagccaa cgagagacag cagctggtgg agacacacat 1440 ggccagagtg gaagccatgc tcaatgaccg ccgccgcctg gccctggaga actacatcac 1500 cgctctgcag gctgttcctc ctcggcctcg tcacgtgttc aatatgctaa agaagtatgt 1560 ccgcgcagaa cagaaggaca gacagcacac cctaaagcat ttcgagcatg tgcgcatggt 1620 ggatcccaag aaagccgctc agatccggtc ccaggttatg acacacctcc gtgtgattta 1680 tgagcgcatg aatcagtctc tctccctgct ctacaacgtg cctgcagtgg ccgaggagat 1740 tcaggatgaa gttgatgagc tgcttcagaa agagcaaaac tattcagatg acgtcttggc 1800 caacatgatt agtgaaccaa ggatcagtta cggaaacgat gctctcatgc catctttgac 1860 cgaaacgaaa accaccgtgg agctccttcc cgtgaatgga gagttcagcc tggacgatct 1920 ccagccgtgg cattcttttg gggctgactc tgtgccagcc aacacagaaa acgaagttga 1980 gcctgttgat gcccgccctg ctgccgaccg aggactgacc actcgaccag gttctgggtt 2040 gacaaatatc aagacggagg agatctctga agtgaagatg gatgcagaat tccgacatga 2100 ctcaggatat gaagttcatc atcaaaaatt ggtgttcttt gcagaagatg tgggttcaaa 2160 caaaggtgca atcattggac tcatggtggg cggtgttgtc atagcgacag tgatcgtcat 2220 caccttggtg atgctgaaga agaaacagta cacatccatt catcatggtg tggtggaggt 2280 tgacgccgct gtcaccccag aggagcgcca cctgtccaag atgcagcaga acggctacga 2340 aaatccaacc tacaagttct ttgagcagat gcagaactag acccccgcca cagcagcctc 2400 tgaagttgga cagcaaaacc attgcttcac tacccatcgg tgtccattta tagaataatg 2460 tgggaagaaa caaacccgtt ttatgattta ctcattatcg ccttttgaca gctgtgctgt 2520 aacacaagta gatgcctgaa cttgaattaa tccacacatc agtaatgtat tctatctctc 2580 tttacatttt ggtctctata ctacattatt aatgggtttt gtgtactgta aagaatttag 2640 ctgtatcaaa ctagtgcatg aatagattct ctcctgatta tttatcacat agccccttag 2700 ccagttgtat attattcttg tggtttgtga cccaattaag tcctacttta catatgcttt 2760 aagaatcgat gggggatgct tcatgtgaac gtgggagttc agctgcttct cttgcctaag 2820 tattcctttc ctgatcacta tgcattttaa agttaaacat ttttaagtat ttcagatgct 2880 ttagagagat tttttttcca tgactgcatt ttactgtaca gattgctgct tctgctatat 2940 ttgtgatata ggaattaaga ggatacacac gtttgtttct tcgtgcctgt tttatgtgca 3000 cacattaggc attgagactt caagcttttc tttttttgtc cacgtatctt tgggtctttg 3060 ataaagaaaa gaatccctgt tcattgtaag cacttttacg gggcgggtgg ggaggggtgc 3120 tctgctggtc ttcaattacc aagaattc 3148 <210> 257 <211> 3614 <212> DNA <213> HUMAN <400> 257 gtccgccaaa acctgcgcgg atagggaaga acagcacccc ggcgccgatt gccgtaccaa 60 acaagcctaa cgtccgctgg gccccggacg ccgcgcggaa aagatgaatt tacaaccaat 120 tttctggatt ggactgatca gttcagtttg ctgtgtgttt gctcaaacag atgaaaatag 180 atgtttaaaa gcaaatgcca aatcatgtgg agaatgtata caagcagggc caaattgtgg 240 gtggtgcaca aattcaacat ttttacagga aggaatgcct acttctgcac gatgtgatga 300 tttagaagcc ttaaaaaaga agggttgccc tccagatgac atagaaaatc ccagaggctc 360 caaagatata aagaaaaata aaaatgtaac caaccgtagc aaaggaacag cagagaagct 420 caagccagag gatattcatc agatccaacc acagcagttg gttttgcgat taagatcagg 480 ggagccacag acatttacat taaaattcaa gagagctgaa gactatccca ttgacctcta 540 ctaccttatg gacctgtctt attcaatgaa agacgatttg gagaatgtaa aaagtcttgg 600 aacagatctg atgaatgaaa tgaggaggat tacttcggac ttcagaattg gatttggctc 660 atttgtggaa aagactgtga tgccttacat tagcacaaca ccagctaagc tcaggaaccc 720 ttgcacaagt gaacagaact gcaccacccc atttagctac aaaaatgtgc tcagtcttac 780 taataaagga gaagtattta atgaacttgt tggaaaacag cgcatatctg gaaatttgga 840 ttctccagaa ggtggtttcg atgccatcat gcaagttgca gtttgtggat cactgattgg 900 ctggaggaat gttacacggc tgctggtgtt ttccacagat gccgggtttc actttgctgg 960 agatgggaaa cttggtggca ttgttttacc aaatgatgga caatgtcacc tggaaaataa 1020 tatgtacaca atgagccatt attatgatta tccttctatt gctcaccttg tccagaaact 1080 gagtgaaaat aatattcaga caatttttgc agttactgaa gaatttcagc ctgtttacaa 1140 ggagctgaaa aacttgatcc ctaagtcagc agtaggaaca ttatctgcaa attctagcaa 1200 tgtaattcag ttgatcattg atgcatacaa ttccctttcc tcagaagtca ttttggaaaa 1260 cggcaaattg tcagaaggag taacaataag ttacaaatct tactgcaaga acggggtgaa 1320 tggaacaggg gaaaatggaa gaaaatgttc caatatttcc attggagatg aggttcaatt 1380 tgaaattagc ataacttcaa ataagtgtcc aaaaaaggat tctgacagct ttaaaattag 1440 gcctctgggc tttacggagg aagtagaggt tattcttcag tacatctgtg aatgtgaatg 1500 ccaaagcgaa ggcatccctg aaagtcccaa gtgtcatgaa ggaaatggga catttgagtg 1560 tggcgcgtgc aggtgcaatg aagggcgtgt tggtagacat tgtgaatgca gcacagatga 1620 agttaacagt gaagacatgg atgcttactg caggaaagaa aacagttcag aaatctgcag 1680 taacaatgga gagtgcgtct gcggacagtg tgtttgtagg aagagggata atacaaatga 1740 aatttattct ggcaaattct gcgagtgtga taatttcaac tgtgatagat ccaatggctt 1800 aatttgtgga ggaaatggtg tttgcaagtg tcgtgtgtgt gagtgcaacc ccaactacac 1860 tggcagtgca tgtgactgtt ctttggatac tagtacttgt gaagccagca acggacagat 1920 ctgcaatggc cggggcatct gcgagtgtgg tgtctgtaag tgtacagatc cgaagtttca 1980 agggcaaacg tgtgagatgt gtcagacctg ccttggtgtc tgtgctgagc ataaagaatg 2040 tgttcagtgc agagccttca ataaaggaga aaagaaagac acatgcacac aggaatgttc 2100 ctattttaac attaccaagg tagaaagtcg ggacaaatta ccccagccgg tccaacctga 2160 tcctgtgtcc cattgtaagg agaaggatgt tgacgactgt tggttctatt ttacgtattc 2220 agtgaatggg aacaacgagg tcatggttca tgttgtggag aatccagagt gtcccactgg 2280 tccagacatc attccaattg tagctggtgt ggttgctgga attgttctta ttggccttgc 2340 attactgctg atatggaagc ttttaatgat aattcatgac agaagggagt ttgctaaatt 2400 tgaaaaggag aaaatgaatg ccaaatggga cacgggtgaa aatcctattt ataagagtgc 2460 cgtaacaact gtggtcaatc cgaagtatga gggaaaatga gtactgcccg tgcaaatccc 2520 acaacactga atgcaaagta gcaatttcca tagtcacagt taggtagctt tagggcaata 2580 ttgccatggt tttactcatg tgcaggtttt gaaaatgtac aatatgtata atttttaaaa 2640 tgttttatta ttttgaaaat aatgttgtaa ttcatgccag ggactgacaa aagacttgag 2700 acaggatggt tattcttgtc agctaaggtc acattgtgcc tttttgacct tttcttcctg 2760 gactattgaa atcaagctta ttggattaag tgatatttct atagcgattg aaagggcaat 2820 agttaaagta atgagcatga tgagagtttc tgttaatcat gtattaaaac tgatttttag 2880 ctttacatat gtcagtttgc agttatgcag aatccaaagt aaatgtcctg ctagctagtt 2940 aaggattgtt ttaaatctgt tattttgcta tttgcctgtt agacatgact gatgacatat 3000 ctgaaagaca agtatgttga gagttgctgg tgtaaaatac gtttgaaata gttgatctac 3060 aaaggccatg ggaaaaattc agagagttag gaaggaaaaa ccaatagctt taaaacctgt 3120 gtgccatttt aagagttact taatgtttgg taacttttat gccttcactt tacaaattca 3180 agccttagat aaaagaaccg agcaattttc tgctaaaaag tccttgattt agcactattt 3240 acatacaggc catactttac aaagtatttg ctgaatgggg accttttgag ttgaatttat 3300 tttattattt ttattttgtt taatgtctgg tgctttctat cacctcttct aatcttttaa 3360 tgtatttgtt tgcaattttg gggtaagact tttttatgag tactttttct ttgaagtttt 3420 agcggtcaat ttgccttttt aatgaacatg tgaagttata ctgtggctat gcaacagctc 3480 tcacctacgc gagtcttact ttgagttagt gccataacag accactgtat gtttacttct 3540 caccatttga gttgcccatc ttgtttcaca ctagtcacat tcttgtttta agtgccttta 3600 gttttaacag ttca 3614 <210> 258 <211> 1193 <212> DNA <213> HUMAN <400> 258 tgaagatcag ctattagaag agaaagatca gttaagtcct ttggacctga tcagcttgat 60 acaagaacta ctgatttcaa cttctttggc ttaattctct cggaaacgat gaaatataca 120 agttatatct tggcttttca gctctgcatc gttttgggtt ctcttggctg ttactgccag 180 gacccatatg taaaagaagc agaaaacctt aagaaatatt ttaatgcagg tcattcagat 240 gtagcggata atggaactct tttcttaggc attttgaaga attggaaaga ggagagtgac 300 agaaaaataa tgcagagcca aattgtctcc ttttacttca aactttttaa aaactttaaa 360 gatgaccaga gcatccaaaa gagtgtggag accatcaagg aagacatgaa tgtcaagttt 420 ttcaatagca acaaaaagaa acgagatgac ttcgaaaagc tgactaatta ttcggtaact 480 gacttgaatg tccaacgcaa agcaatacat gaactcatcc aagtgatggc tgaactgtcg 540 ccagcagcta aaacagggaa gcgaaaaagg agtcagatgc tgtttcaagg tcgaagagca 600 tcccagtaat ggttgtcctg cctgcaatat ttgaatttta aatctaaatc tatttattaa 660 tatttaacat tatttatatg gggaatatat ttttagactc atcaatcaaa taagtattta 720 taatagcaac ttttgtgtaa tgaaaatgaa tatctattaa tatatgtatt atttataatt 780 cctatatcct gtgactgtct cacttaatcc tttgttttct gactaattag gcaaggctat 840 gtgattacaa ggctttatct caggggccaa ctaggcagcc aacctaagca agatcccatg 900 ggttgtgtgt ttatttcact tgatgataca atgaacactt ataagtgaag tgatactatc 960 cagttactgc cggtttgaaa atatgcctgc aatctgagcc agtgctttaa tggcatgtca 1020 gacagaactt gaatgtgtca ggtgaccctg atgaaaacat agcatctcag gagatttcat 1080 gcctggtgct tccaaatatt gttgacaact gtgactgtac ccaaatggaa agtaactcat 1140 ttgttaaaat tatcaatatc taatatatat gaataaagtg taagttcaca act 1193 <210> 259 <211> 1676 <212> DNA <213> HUMAN <400> 259 gaattccgcc gctgaccgag gcgtgcaaag actccagaat tggaggcatg atgaagactc 60 tgctgctgtt tgtggggctg ctgctgacct gggagagtgg gcaggtcctg ggggaccaga 120 cggtctcaga caatgagctc caggaaatgt ccaatcaggg aagtaagtac gtcaataagg 180 aaattcaaaa tgctgtcaac ggggtgaaac agataaagac tctcatagaa aaaacaaacg 240 aagagcgcaa gacactgctc agcaacctag aagaagccaa gaagaagaaa gaggatgccc 300 taaatgagac cagggaatca gagacaaagc tgaaggagct cccaggagtg tgcaatgaga 360 ccatgatggc cctctgggaa gagtgtaagc cctgcctgaa acagacctgc atgaagttct 420 acgcacgcgt ctgcagaagt ggctcaggcc tggttggccg ccagcttgag gagttcctga 480 accagagctc gcccttctac ttctggatga atggtgaccg catcgactcc ctgctggaga 540 acgaccggca gcagacgcac atgctggatg tcatgcagga ccacttcagc cgcgcgtcca 600 gcatcataga cgagctcttc caggacaggt tcttcacccg ggagccccag gatacctacc 660 actacctgcc cttcagcctg ccccaccgga ggcctcactt cttctttccc aagtcccgca 720 tcgtccgcag cttgatgccc ttctctccgt acgagcccct gaacttccac gccatgttcc 780 agcccttcct tgagatgata cacgaggctc agcaggccat ggacatccac ttccacagcc 840 cggccttcca gcacccgcca acagaattca tacgagaagg cgacgatgac cggactgtgt 900 gccgggagat ccgccacaac tccacgggct gcctgcggat gaaggaccag tgtgacaagt 960 gccgggagat cttgtctgtg gactgttcca ccaacaaccc ctcccaggct aagctgcggc 1020 gggagctcga cgaatccctc caggtcgctg agaggttgac caggaaatac aacgagctgc 1080 taaagtccta ccagtggaag atgctcaaca cctcctcctt gctggagcag ctgaacgagc 1140 agtttaactg ggtgtcccgg ctggcaaacc tcacgcaagg cgaagaccag tactatctgc 1200 gggtcaccac ggtggcttcc cacacttctg actcggacgt tccttccggt gtcactgagg 1260 tggtcgtgaa gctctttgac tctgatccca tcactgtgac ggtccctgta gaagtctcca 1320 ggaagaaccc taaatttatg gagaccgtgg cggagaaagc gctgcaggaa taccgcaaaa 1380 agcaccggga ggagtgagat gtggatgttg cttttgcacc ttacgggggc atcttgagtc 1440 cagctccccc caagatgagc tgcagccccc cagagagagc tctgcacgtc accaagtaac 1500 caggccccag cctccaggcc cccaactccg cccagcctct ccccgctctg gatcctgcac 1560 tctaacactc gactctgctg ctcatgggaa gaacagaatt gctcctgcat gcaactaatt 1620 caataaaact gtcttgtgag ctgaaaaaaa aaaaaaaaaa aaaaaaaaag gaattc 1676 <210> 260 <211> 1650 <212> DNA <213> HUMAN <400> 260 agcgagccgc cacggtatga ccccaggggc tctgctgatg ctgctggggg cgctggggcc 60 gccgctcgcc ccaggcgtcc gcggctcgga ggcggagggt cgactccggg agaaactttt 120 ctctggctat gatagctccg tgcggccagc gcgggaggtg ggagaccgtg tcagggtcag 180 cgttggtctc atcctggcgc aactcatcag cctgaacgag aaggatgaag agatgagcac 240 aaaggtgtac ttagacctgg agtggactga ctacaggctg agctgggacc ctgcggagca 300 cgacggcatc gattcgctcc gcatcacggc ggaatccgtg tggctccctg acgtggtgct 360 actgaacaac aatgatggga attttgacgt ggctctggac attagcgtcg tggtgtcctc 420 cgacggctcc gtgcgttggc aacccccggg catctatcgc agcagctgca gcatccaggt 480 cacctacttc cccttcgact ggcagaattg cactatggtg ttcagctcct acagctacga 540 cagctcggag gtcagcctgc agacaggcct gggtcctgac gggcaagggc atcaggaaat 600 ccacattcat gaagggactt tcattgagaa tggccagtgg gagaatatcc acaagccctc 660 tcggctaatc cagcctccag gcgatcctag gggagggagg gaaggacagc gccaggaagt 720 catcttctac ctcatcatcc gccgcaagcc tctcttctac ctggtcaacg tcattgcccc 780 atgcatcctc atcactcttc tggccatctt cgtcttctac ctgccaccag atgcaggaga 840 gaagatgggg ctctcaatct ttgccctgct gacccttact gtgttcctgc tgctgctggc 900 tgacaaagta cctgagacct cactatcagt acccattatt atcaagtacc tcatgtttac 960 catggtcctc gtcaccttct cagtcatcct tagtgtcgtg gttctcaacc tgcaccaccg 1020 ctcaccccac acccaccaaa tgcccctttg ggtccgtcag atcttcattc acaaacttcc 1080 gctgtacctg cgtctaaaaa ggcccaaacc cgagagagac ctgatgccgg agccccctca 1140 ctgttcttct ccaggaagtg gctggggtcg gggaacagat gaatatttca tccggaagcc 1200 gccaagtgat tttctcttcc ccaaacccaa taggttccag cctgaactgt ctgcccctga 1260 tctgcggcga tttatcgatg gtccaaaccg ggctgtggcc ctgcttccgg agctacggga 1320 ggtcgtctcc tctatcagct acatcgctcg acagctgcag gaacaggagg accacgatgc 1380 gctgaaggag gactggcagt ttgtggccat ggtagtggac cgcctcttcc tgtggacttt 1440 catcatcttc accagcgttg ggaccctagt catcttcctg gacgccacgt accacttgcc 1500 ccctccagac ccctttcctt gaagactgga gggttgagac caggccccct gccagttgaa 1560 gtgagagagt ttggtgatac tgtcaagccc tatccttctc tgcctcttaa ctccttcacg 1620 aggaatctgg gcctcttatt tcgttctggg 1650 <210> 261 <211> 1041 <212> DNA <213> HUMAN <400> 261 ctaaagatct ccctccaggc agcccttggc tggtccctgc gagcccgtgg agactgccag 60 agatgtcctc tttcggttac aggaccctga ctgtggccct cttcaccctg atctgctgtc 120 caggatcgga tgagaaggta ttcgaggtac acgtgaggcc aaagaagctg gcggttgagc 180 ccaaagggtc cctcgaggtc aactgcagca ccacctgtaa ccagcctgaa gtgggtggtc 240 tggagacctc tctaaataag attctgctgg acgaacaggc tcagtggaaa cattacttgg 300 tctcaaacat ctcccatgac acggtcctcc aatgccactt cacctgctcc gggaagcagg 360 agtcaatgaa ttccaacgtc agcgtgtacc agcctccaag gcaggtcatc ctgacactgc 420 aacccacttt ggtggctgtg ggcaagtcct tcaccattga gtgcagggtg cccaccgtgg 480 agcccctgga cagcctcacc ctcttcctgt tccgtggcaa tgagactctg cactatgaga 540 ccttcgggaa ggcagcccct gctccgcagg aggccacagc cacattcaac agcacggctg 600 acagagagga tggccaccgc aacttctcct gcctggctgt gctggacttg atgtctcgcg 660 gtggcaacat ctttcacaaa cactcagccc cgaagatgtt ggagatctat gagcctgtgt 720 cggacagcca gatggtcatc atagtcacgg tggtgtcggt gttgctgtcc ctgttcgtga 780 catctgtcct gctctgcttc atcttcggcc agcacttgcg ccagcagcgg atgggcacct 840 acggggtgcg agcggcttgg aggaggctgc cccaggcctt ccggccatag caaccatgag 900 tggcatggcc accaccacgg tggtcactgg aactcagtgt gactcctcag ggttgaggtc 960 cagccctggc tgaaggactg tgacaggcag cagagacttg ggacattgcc ttttctagcc 1020 cgaatacaaa cacctggact t 1041 <210> 262 <211> 1211 <212> DNA <213> HUMAN <400> 262 ggcccccccc ccccctagaa atgctcgaac caggacggct cctggagtcc tcgcgccctc 60 gcagaaggac tacgggcccc ggcgaccccg ggggcggggc ttccggcgcg ctgccttgtg 120 ggcacggtag ttccgccggg tctggcttcc gcctgccgag cggccccgga ccgcaggccg 180 gactacactt cccgtcggcc cgcctgctct cccgatgccg ccttggcgcg agacgttggc 240 aagcagagtg tctccaagat ggccgcttgg ggaaggaggc gtcttggccc gggcagcagt 300 ggcggcagcg cccgagagag ggtgagcttg tcggccacag actgctacat tgtgcatgag 360 atctacaatg gggagaatgc ccaagaccag tttgagtacg agctggagca ggccctggaa 420 gcccagtaca agtacattgt gattgagccc actcgcattg gcgacgagac agcccgctgg 480 atcaccgtgg gcaactgcct gcacaagacg gccgtgctgg cgggcaccgc ctgcctcttc 540 accccgttgg cgctgccctt agattattcc cactacattt ccctgcccgc tggtgtgctg 600 agcctggcct gctgcaccct ctatgggatc tcctggcagt ttgacccttg ctgcaagtac 660 caagtggagt acgacgccta taaactgtcg cgcctgcctc tgcacacact cacctcctcc 720 accccggtgg tgctggtccg gaaggacgac ctgcacagaa agagactgca caacacgata 780 gcactggccg ccctggtgta ctgtgtaaag aagatttacg aactctatgc cgtatgattt 840 cagtagaaca gggagcgaag caaaaccacc cggcccacaa gagacaacag agtattcaga 900 tcgccacact ctgtgaggca gcagagcctg ggcaggtgtt tggcttagta tttgttattt 960 ttaaaaaata acagatcacg ggtgtaccca gggtttttca gctcattaca ctaagatgtg 1020 gatttccata acccaagagg ggggtctgag gctgtggaag tccgactggg cagtggaatg 1080 ctgatggagg cagacgctgc cgagggggtg tggacgtgct ttgggggagg tctttaagtc 1140 tattgtttaa ctgtaccatc cagagcccac cagaagctat tgatcattaa aattatgaga 1200 atttcaactc c 1211 <210> 263 <211> 540 <212> DNA <213> HUMAN <400> 263 tgcgttttgg gggttcctgg agtatcaatc atggatcaag aaactgtagg caatgttgtc 60 ctgttggcca tcgtcaccct catcagcgtg gtccagaatg gattctttgc ccataaagtg 120 gagcacgaaa gcaggaccca gaatgggagg agcttccaga ggaccggaac acttgccttt 180 gagcgggtct acactgccaa ccagaactgt gtagatgcgt accccacttt cctcgctgtg 240 ctctggtctg cggggctact ttgcagccaa gttcctgctg cgtttgctgg actgatgtac 300 ttgtttgtgc ggcaaaagta ctttgtcggt tacctaggag agagaacgca gagcacccct 360 ggctacatat ttgggaaacg catcatactc ttcctgttcc tcatgtccgt tgctggcata 420 ttcaactatt acctcatctt ctttttcgga agtgactttg aaaactacat aaagacgatc 480 tccaccacca tctcccctct acttctcatt tcctaactct ctgctgaata tggggttggt 540 <210> 264 <211> 1141 <212> DNA <213> HUMAN <400> 264 ggaattccgc ttaggacagt tggctgttaa gtgacactga ttctccccgc cccgcctgac 60 ccccgagaag gaggcttgtc ccccgctgcg tgagggggtg gggaagtggg tagtgaattc 120 ggatctacct gggagggggg agtggaagtt cccgccccgg agagcggcga ggcggcagcc 180 acagttgatt atggaagatt cccacaagag taccacgtca gagacagcac ctcaacctgg 240 ttcagcagtt cagggagctc acatttctca tattgctcaa caggtatcat ctttatcaga 300 aagtgaggag tcccaggact catccgacag cataggctcc tcacagaaag cccacgggat 360 cctagcacgg cgcccatctt acagaaaaat tttgaaagac ttatcttctg aagatacacg 420 gggcagaaaa ggagacggag aaaattctgg agtttctgct gctgtcactt ctatgtctgt 480 tccaactccc atctatcaga ctagcagcgg acagtacatt gccattgccc caaatggagc 540 cttacagttg gcaagtccag gcacagatgg agtacaggga cttcagacat taaccatgac 600 aaattcaggc agtactcagc aaggtacaac tattcttcag tatgcacaga cctctgatgg 660 acagcagata cttgtgccca gcaatcaggt ggtcgtacaa actgcatcag gagatatgca 720 aacatatcag atccgaacta caccttcagc tacttctctg ccacaaactg tggtgatgac 780 atctcctgtg actctcacct ctcagacaac taagacagat gacccccaat tgaaaagaga 840 aataaggtta atgaaaaaca gagaagctgc tcgagaatgt cgcagaaaga agaaagaata 900 tgtgaaatgc ctggaaaacc gagttgcagt cctggaaaat caaaataaaa ctctaataga 960 agagttaaaa actttgaagg atctttattc caataaaagt gtttgattcc taagaaagaa 1020 aatatttttg tggacatgca taaaaattaa atggatttcc tagtggagtt ttataaatta 1080 aaaggtcaaa catgaagctt tttatttagg cttttccaaa tcaaggataa atatcttacg 1140 c 1141 <210> 265 <211> 1766 <212> DNA <213> HUMAN <400> 265 cgcgccaccg ccgccgccca ggccatcgcc accctccgca gccatgtcca ccaggtccgt 60 gtcctcgtcc tcctaccgca ggatgttcgg cggcccgggc accgcgagcc ggccgagctc 120 cagccggagc tacgtgacta cgtccacccg cacctacagc ctgggcagcg cgctgcgccc 180 cagcaccagc cgcagcctct acgcctcgtc cccgggcggc gtgtatgcca cgcgctcctc 240 tgccgtgcgc ctgcggagca gcgtgcccgg ggtgcggctc ctgcaggact cggtggactt 300 ctcgctggcc gacgccatca acaccgagtt caagaacacc cgcaccaacg agaaggtgga 360 gctgcaggag ctgaatgacc gcttcgccaa ctacatcgac aaggtgcgct tcctggagca 420 gcagaataag atcctgctgg ccgagctcga gcagctcaag ggccaaggca agtcgcgcct 480 gggggacctc tacgaggagg agatgcggga gctgcgccgg caggtggacc agctaaccaa 540 cgacaaagcc cgcgtcgagg tggagcgcga caacctggcc gaggacatca tgcgcctccg 600 ggagaaattg caggaggaga tgcttcagag agaggaagcc gaaaacaccc tgcaatcttt 660 cagacaggat gttgacaatg cgtctctggc acgtcttgac cttgaacgca aagtggaatc 720 tttgcaagaa gagattgcct ttttgaagaa actccacgaa gaggaaatcc aggagctgca 780 ggctcagatt caggaacagc atgtccaaat cgatgtggat gtttccaagc ctgacctcac 840 ggctgccctg cgtgacgtac gtcagcaata tgaaagtgtg gctgccaaga acctgcagga 900 ggcagaagaa tggtacaaat ccaagtttgc tgacctctct gaggctgcca accggaacaa 960 tgacgccctg cgccaggcaa agcaggagtc cactgagtac cggagacagg tgcagtccct 1020 cacctgtgaa gtggatgccc ttaaaggaac caatgagtcc ctggaacgcc agatgcgtga 1080 aatggaagag aactttgccg ttgaagctgc taactaccaa gacactattg gccgcctgca 1140 ggatgagatt cagaatatga aggaggaaat ggctcgtcac cttcgtgaat accaagacct 1200 gctcaatgtt aagatggccc ttgacattga gattgccacc tacaggaagc tgctggaagg 1260 cgaggagagc aggatttctc tgcctcttcc aaacttttcc tccctgaacc tgagggaaac 1320 taatctggat tcactccctc tggttgatac ccactcaaaa aggacacttc tgattaagac 1380 ggttgaaact agagatggac aggttatcaa cgaaacttct cagcatcacg atgaccttga 1440 ataaaaattg cacacactca gtgcagcaat atattaccag caagaataaa aaagaaatcc 1500 atatcttaaa gaaacagctt tcaagtgcct ttctgcagtt tttcaggagc gcaagataga 1560 tttggaatag gaataagctc tagttcttaa caaccgacac tcctacaaga tttagaaaaa 1620 agtttacaac ataatctagt ttacagaaaa atcttgtgct agaatacttt ttaaaaggta 1680 ttttgaatac cattaaaact gctttttttt ttccagcaag tatccaacca acttggttct 1740 gcttcaataa atctttggaa aaacta 1766 <210> 266 <211> 1315 <212> DNA <213> HUMAN <400> 266 gaggcggctg cctgctgctc tgcaggtacc atggagctga gctataggct cttcatctgc 60 ctcctgctct ggggtagtac tgagctgtgc tacccccaac ccctctggct cttgcagggt 120 ggagccagcc atcctgagac gtccgtacag cccgtactgg tggagtgtca ggaggccact 180 ctgatggtca tggtcagcaa agaccttttt ggcaccggga agctcatcag ggctgctgac 240 ctcaccttgg gcccagaggc ctgtgagcct ctggtctcca tggacacaga agatgtggtc 300 aggtttgagg ttggactcca cgagtgtggc aacagcatgc aggtaactga cgatgccctg 360 gtgtacagca ccttcctgct ccatgacccc cgccccgtgg gaaacctgtc catcgtgagg 420 actaaccgcg cagagattcc catcgagtgc cgctacccca ggcagggcaa tgtgagcagc 480 caggccatcc tgcccacctg gttgcccttc aggaccacgg tgttctcaga ggagaagctg 540 actttctctc tgcgtctgat ggaggagaac tggaacgctg agaagaggtc ccccaccttc 600 cacctgggag atgcagccca cctccaggca gaaatccaca ctggcagcca cgtgccactg 660 cggttgtttg tggaccactg cgtggccaca ccgacaccag accagaatgc ctccccttat 720 cacaccatcg tggacttcca tggctgtctt gtcgacggtc tcactgatgc ctcttctgca 780 ttcaaagttc ctcgacccgg gccagataca ctccagttca cagtggatgt cttccacttt 840 gctaatgact ccagaaacat gatatacatc acctgccacc tgaaggtcac cctagctgag 900 caggacccag atgaactcaa caaggcctgt tccttcagca agccttccaa cagctggttc 960 ccagtggaag gcccggctga catctgtcaa tgctgtaaca aaggtgactg tggcactcca 1020 agccattcca ggaggcagcc tcatgtcatg agccagtggt ccacgtctgc ttcccgtaac 1080 cgcaggcatg tgacagaaga agcagatgtc accgtggggg ccactgatct tcctggacag 1140 gagtggtgac catgaagtag agcagtgggc tttgccttct gacacctcag tggtgctgct 1200 gggcgtaggc ctggctgtgg tggtgtccct gactctgact gctgttatcc tggttctcac 1260 caggaggtgt cgcactgcct cccaccctgt gtctgcttcc gaataaaaga agaaa 1315 <210> 267 <211> 659 <212> DNA <213> HUMAN <400> 267 gggtacctgt gtggaaagaa gcaaccacca ctctattttg tgcatcagat gctaaagcat 60 atgatacaga ggtacataat gtttgggcca cacatgcctg tgtacccaca gaccccaacc 120 cacaagaaat agtattgaaa aatgtgacag aaaattttaa catgtggaaa aataacatgg 180 tagaacagat gcatgaggat ataatcagtt tatgggatca aagcctaaaa ccatgtgtaa 240 aattaacccc actctgtgtt actttaaatt gcactgattt gacgaatgct actaatacca 300 ctagtagtag cgggggaacg atggagggag gagaaataaa aaactgctct ttcaatatca 360 ccacaagcat aagagataag gtgcagaaag aatatgcact gttttataaa cttgatatag 420 taccaataga taataatact agctataggt tgataagttg taacacctca gtcatcacac 480 aggcctgtcc aaaggtatcc tttgagccaa ttcccataca ttattgtgcc ccggctggtt 540 ttgcgattct aaagtgtaaa gataagaagt tcaatggaaa aggaccatgt acaaatgtca 600 gcacagtaca atgtacacat ggaattaggc cagtagtatc aactcaactg ctgttaaat 659 <210> 268 <211> 2824 <212> DNA <213> HUMAN <400> 268 gcggccgctt tcgatttcgc tttcccctaa atggctgagc ttctcgccag cgcaggatca 60 gcctgttcct gggactttcc gagagccccg ccctcgttcc ctcccccagc cgccagtagg 120 ggaggactcg gcggtacccg gagcttcagg ccccaccggg gcgcggagag tcccagaccc 180 ggccgggacc gggacggcgt ccgagtgcca atggctagct ctaggtgtcc cgctccccgc 240 gggtgccgct gcctccccgg agcttctctc gcatggctgg ggacagtact gctacttctc 300 gccgactggg tgctgctccg gaccgcgctg ccccgcatat tctccctgct ggtgcccacc 360 gcgctgccac tgctccgggt ctgggcggtg ggcctgagcc gctgggccgt gctctggctg 420 ggggcctgcg gggtcctcag ggcaacggtt ggctccaaga gcgaaaacgc aggtgcccag 480 ggctggctgg ctgctttgaa gccattagct gcggcactgg gcttggccct gccgggactt 540 gccttgttcc gagagctgat ctcatgggga gcccccgggt ccgcggatag caccaggcta 600 ctgcactggg gaagtcaccc taccgccttc gttgtcagtt atgcagcggc actgcccgca 660 gcagccctgt ggcacaaact cgggagcctc tgggtgcccg gcggtcaggg cggctctgga 720 aaccctgtgc gtcggcttct aggctgcctg ggctcggaga cgcgccgcct ctcgctgttc 780 ctggtcctgg tggtcctctc ctctcttggg gagatggcca ttccattctt tacgggccgc 840 ctcactgact ggattctaca agatggctca gccgatacct tcactcgaaa cttaactctc 900 atgtccattc tcaccatagc cagtgcagtg ctggagttcg tgggtgacgg gatctataac 960 aacaccatgg gccacgtgca cagccacttg cagggagagg tgtttggggc tgtcctgcgc 1020 caggagacgg agtttttcca acagaaccag acaggtaaca tcatgtctcg ggtaacagag 1080 gacacgtcca ccctgagtga ttctctgagt gagaatctga gcttatttct gtggtacctg 1140 gtgcgaggcc tatgtctctt ggggatcatg ctctggggat cagtgtccct caccatggtc 1200 accctgatca ccctgcctct gcttttcctt ctgcccaaga aggtgggaaa atggtaccag 1260 ttgctggaag tgcaggtgcg ggaatctctg gcaaagtcca gccaggtggc cattgaggct 1320 ctgtcggcca tgcctacagt tcgaagcttt gccaacgagg agggcgaagc ccagaagttt 1380 agggaaaagc tgcaagaaat aaagacactc aaccagaagg aggctgtggc ctatgcagtc 1440 aactcctgga ccactagtat ttcaggtatg ctgctgaaag tgggaatcct ctacattggt 1500 gggcagctgg tgaccagtgg ggctgtaagc agtgggaacc ttgtcacatt tgttctctac 1560 cagatgcagt tcacccaggc tgtggaggta ctgctctcca tctaccccag agtacagaag 1620 gctgtgggct cctcagagaa aatatttgag tacctggacc gcacccctcg ctgcccaccc 1680 agtggtctgt tgactccctt acacttggag ggccttgtcc agttccaaga tgtctccttt 1740 gcctacccaa accgcccaga tgtcttagtg ctacaggggc tgacattcac cctacgccct 1800 ggcgaggtga cggcgctggt gggacccaat gggtctggga agagcacagt ggctgccctg 1860 ctgcagaatc tgtaccagcc caccggggga cagctgctgt tggatgggaa gccccttccc 1920 caatatgagc accgctacct gcacaggcag gtggctgcag tgggacaaga gccacaggta 1980 tttggaagaa gtcttcaaga aaatattgcc tatggcctga cccagaagcc aactatggag 2040 gaaatcacag ctgctgcagt aaagtctggg gcccatagtt tcatctctgg actccctcag 2100 ggctatgaca cagaggtaga cgaggctggg agccagctgt cagggggtca gcgacaggca 2160 gtggcgttgg cccgagcatt gatccggaaa ccgtgtgtac ttatcctgga tgatgccacc 2220 agtgccctgg atgcaaacag ccagttacag gtggagcagc tcctgtacga aagccctgag 2280 cggtactccc gctcagtgct tctcatcacc cagcacctca gcctggtgga gcaggctgac 2340 cacatcctct ttctggaagg aggcgctatc cgggaggggg gaacccacca gcagctcatg 2400 gagaaaaagg ggtgctactg ggccatggtg caggctcctg cagatgctcc agaatgaaag 2460 ccttctcaga cctgcgcact ccatctccct cccttttctt ctctctgtgg tggagaacca 2520 cagctgcaga gtagcagctg cctccaggat gagttacttg aaatttgcct tgagtgtgtt 2580 acctcctttc caagctcctc gtgataatgc agacttcctg gagtacaaac acaggatttg 2640 taattcctac tgtaacggag tttagagcca gggctgatgc tttggtgtgg ccagcactct 2700 gaaactgaga aatgttcaga atgtacggaa agatgatcag ctattttcaa cataactgaa 2760 ggcatatgct ggcccataaa caccctgtag gttcttgata tttataataa aattggtgtt 2820 ttgt 2824 <210> 269 <211> 3285 <212> DNA <213> HUMAN <400> 269 cggctcgctg gtaccggcag tgccatggcg gccttcagca agtacttgac ggcgcgaaac 60 tcctcgctgg ctggtgccgc gttcctgctg ctctgcctgc tccacaagcg gcgccgcgcc 120 ctcggcctgc acggtaagaa aagtggaaaa ccaccattac agaataatga gaaagaagga 180 aaaaaagaac gagctgtggt ggacaaagtg tttttctcaa ggctcataca gatcctgaaa 240 atcatggtcc ctagaacatt ttgtaaagag acaggttact tggtacttat tgctgttatg 300 ctggtgtctc gaacatattg tgatgtttgg atgattcaaa atgggacact aattgaaagt 360 ggtatcattg gtcgtagcag gaaagatttc aagagatact tactcaactt catcgctgcc 420 atgcctctta tctctctggt taataacttc ttgaagtatg ggttaaatga gcttaaactg 480 tgcttccgag taaggctcac taaatacctc tatgaggagt atcttcaagc cttcacatat 540 tataaaaagg ggaatctgga caacagaata gctaatccag accagctgct tacacaagat 600 gtagaaaaat tttgtaacag tgtagtcgat ctgtattcaa atcttagtaa gccattttta 660 gacatagttt tgtatatctt taagttaacg agtgcaattg gagctcaggg cccagcgagc 720 atgatggcct acttggttgt ttctgggcta ttcctaactc gacttcgaag acccattggt 780 aagatgacaa taactgagca aaagtatgaa ggagaatata gatatgttaa ttctcggctc 840 atcacaaaca gtgaagaaat tgccttttac aatgggaata aaagagaaaa gcagacagtc 900 cactcagtct tccgaaaact ggtggaacac ctacataatt tcattttgtt tcggttttca 960 atgggcttca ttgatagtat tattgccaaa taccttgcca ctgttgttgg ttacctagtt 1020 gtcagtcgcc ctttcttaga tttgtctcat cctcgacatc tcaagagtac acattcggaa 1080 cttctagagg attactacca aagtggaaga atgcttttgc gaatgtctca agctctgggt 1140 cgaatagttt tggctgggcg tgaaatgact agattggccg gttttactgc tcggattaca 1200 gaattaatgc aagtactgaa ggatttaaat catggcaaat atgagcgcac aatggtctca 1260 caacaggaaa agggtattga aggagtacaa gtcattccct tgatacctgg tgctggagaa 1320 atcattattg cagataacat tataaagttt gatcatgttc ctttagcaac gccaaatgga 1380 gatgttttga tccgagacct taattttgaa gttcgatctg gggctaatgt tctaatttgt 1440 ggtccaaatg gctgcggaaa gagttcactt ttccgtgttc ttggtgaatt atggcctctt 1500 tttggaggac gtctaactaa acctgaaaga agaaaattat tttatgttcc tcagagacct 1560 tacatgaccc ttggaacact tcgagatcaa gtgatatatc cagatggacg agaagatcag 1620 aaaaggaagg gaatttctga cctagtacag aaggaatact tagacaatgt ccagttgggt 1680 catatccttg aacgtgaagg aggctgggac agtgttcagg attggatgga cgtactcagt 1740 ggtggagaaa agcaaagaat ggcgatggca agattatttt atcataaacc ccagtttgcc 1800 attttggatg aatgcacaag tgcagttagt gtcgacgtgg aaggctacat ttatagtcat 1860 tgtcgaaagg ttggcatcac tctcttcact gtgtctcata ggaaatctct ttggaaacat 1920 catgagtact acctgcatat ggatggcaga ggcaactatg aattcaaaca gataacagaa 1980 gatacagttg agtttggctc ttagagaaat ctggagaact atacctgctt cagtgaaata 2040 attacagaat atacttagaa aggcaaagta cattgtaaaa taaagttgag cttagttttt 2100 tttaaaaaaa aaaacaaagc caaccaaatt atattagata cagaataatg gagaacaagt 2160 tgttaaaaca tttaatatta tataggatat tgctaattgt gtatatgttg gtttaattaa 2220 taatatgtac taagaatgtc cttattcttg tggttaaaaa cctgcctaaa ttaaattggg 2280 cttcaatcat gtaacctgat tcatcctggg atgtaaacca ttcgaagtca gctaattgga 2340 cttttatggc tctatctttt ccttcatgaa gaaccctatt taaaactggg tcatcatttg 2400 tcctgttcta gcaagatagt cttcagtttc atttcctgtg ccctgtggta gttggaaacc 2460 atatcataat gtattattta aatgtttaac atcattgcat aacacgttta ttatacagtg 2520 gcagatttct ttagctgcca cagtaatact cattccttgt gtgtgtcttg gagtgcattt 2580 gactccagga aaagccattt tggttttcct taactaaatg ataaatgtac ccctctcagt 2640 ctgcagtatt gagttgttta aagtatatgt gcagtcttgc ttacaaggag gggttaccat 2700 gtatcacacc taatcttccc aatgtttggg aatattaaaa caccaacagt ccttaacatg 2760 ccaggctcaa ggtcttataa gagttctaga tttttaagag aattagacaa atttgtgtgt 2820 gttagaagcc cattcattag aagtgtggtg gttatttggt attaaactca aacagtgcca 2880 agcttgggaa ggcactacaa tgaaataatg cactgagtat gcaatgctat cactgtcttt 2940 gactgtgatt ttatgtttaa aaagtatgtt ctaaaattat tatatataca tgggtgaatt 3000 atgtttccga ggcactgttt tatctctgtg aatcttgaat aactttttta tatttgggtt 3060 atgatgtcaa acgatcctaa gcgaagatga tttcagttca tcaaatcatc attaatgact 3120 ttatgtatta tttgcacagg gagaattgaa actgagtata atcaataagc tagatacgaa 3180 atcagtttct caaactgagc ttcagaaagg ggcattttgt actcttgttt ttgcataact 3240 ggttttgttt ttttgcagaa ttaactataa caatcactgg ctacg 3285 <210> 270 <211> 1004 <212> DNA <213> HUMAN <400> 270 gcctcgctcg ggcgcccagt ggtcctgccg cctggtctca cctcgccatg gttcgtctgc 60 ctctgcagtg cgtcctctgg ggctgcttgc tgaccgctgt ccatccagaa ccacccactg 120 catgcagaga aaaacagtac ctaataaaca gtcagtgctg ttctttgtgc cagccaggac 180 agaaactggt gagtgactgc acagagttca ctgaaacgga atgccttcct tgcggtgaaa 240 gcgaattcct agacacctgg aacagagaga cacactgcca ccagcacaaa tactgcgacc 300 ccaacctagg gcttcgggtc cagcagaagg gcacctcaga aacagacacc atctgcacct 360 gtgaagaagg ctggcactgt acgagtgagg cctgtgagag ctgtgtcctg caccgctcat 420 gctcgcccgg ctttggggtc aagcagattg ctacaggggt ttctgatacc atctgcgagc 480 cctgcccagt cggcttcttc tccaatgtgt catctgcttt cgaaaaatgt cacccttgga 540 caagctgtga gaccaaagac ctggttgtgc aacaggcagg cacaaacaag actgatgttg 600 tctgtggtcc ccaggatcgg ctgagagccc tggtggtgat ccccatcatc ttcgggatcc 660 tgtttgccat cctcttggtg ctggtcttta tcaaaaaggt ggccaagaag ccaaccaata 720 aggcccccca ccccaagcag gaaccccagg agatcaattt tcccgacgat cttcctggct 780 ccaacactgc tgctccagtg caggagactt tacatggatg ccaaccggtc acccaggagg 840 atggcaaaga gagtcgcatc tcagtgcagg agagacagtg aggctgcacc cacccaggag 900 tgtggccacg tgggcaaaca ggcagttggc cagagagcct ggtgctgctg ctgcaggggt 960 gcaggcagaa gcggggagct atgcccagtc agtgccagcc cctc 1004 <210> 271 <211> 1677 <212> DNA <213> HUMAN <400> 271 atggataatc tcagtgatac cttgaagaag ctgaagataa cagctgttga caagactgag 60 gatagtttag aaggatgctt ggattgtctg cttcaagccc tggctcaaaa taatacggaa 120 acaagtgaaa aaatccaagc aagtggaata cttcagctgt ttgcaagtct gttgactcca 180 cagtcttcct gcaaagccaa agtagctaac atcatagcag aagtagccaa aaatgagttt 240 atgcgaattc catgtgtgga tgctggattg atttcaccac tggtgcagct gctaaatagc 300 aaagaccagg aagtgctgct tcaaacgggc agggctctag gaaacatatg ttacgatagc 360 cattcgcttc aagctcagct tatcaatatg ggtgttattc ctaccttagt gaaattactg 420 ggcatccact gccaaaatgc agctcttaca gaaatgtgtc ttgttgcatt tggtaattta 480 gcagaacttg agtcaagtaa agaacagttt gccagtacaa acattgctga agagctagta 540 aaactcttca agaaacaaat cgaacatgat aagagagaaa tgatttttga agttcttgct 600 ccattggcag aaaatgatgc tattaaacta cagctggttg aagcaggcct agtagagtgt 660 ctactagaga ttgttcagca aaaagtggat agtgacaaag aagatgatat tactgagctc 720 aaaactggtt cagatctcat ggttttatta cttcttggag atgaatccat gcagaagtta 780 tttgaaggag gaaaaggtag tgtatttcaa agggtactct cttggatccc atcaaataac 840 caccagctac agcttgctgg agcattggca attgcaaatt ttgccagaaa tgatgcaaat 900 tgtattcata tggtagacaa tgggattgta gaaaaactta tggatttact ggacagacat 960 gtagaagatg gaaatgtaac agtacagcat gcagcactaa gtgccctcag aaacctggcc 1020 attccagtta tagataaagc aaagatgtta tcagctgggg tcacagaggc agttttgaaa 1080 tttcttaaat ctgaaatgcc tcctgttcag ttcaaacttc tgggaacatt aagaatgtta 1140 atagatgcac aagcagaagc tgctgaacaa ttgggaaaga atgttaagtt agtggagcgt 1200 ttggtggaat ggtgtgaagc caaagatcat gctggtgtga tgggggagtc aaacagactg 1260 ctgtctgccc ttatacgaca cagtaaatca aaagatgtaa ttaaaaccat tgtgcagagt 1320 ggtggcatca agcatctagt taccatggca actagtgaac atgtaataat gcagaatgaa 1380 gctcttgttg ctttggcatt aatagcagct ttagaattgg gcactgctga gaaagatcta 1440 gaaagtgcta aacttgtaca gattttacat agactgctag cagatgagag aagtgctcct 1500 gaaatcaaat ataattccat ggtcctgata tgtgctctta tgggatctga atgtctacac 1560 aaggaagtac aggatttggc ttttctagat gtcgtatcca aacttcgcag tcatgagaac 1620 aaaagtgttc gccagcaggc ctctctcaca gagcagagac ttactgtgga aagctga 1677 <210> 272 <211> 8201 <212> DNA <213> HUMAN <400> 272 ctaaaaatac cattaagtaa tagtattagc ttttgtattc tgagattcaa cagcagcagt 60 cacttccctc cactcctatg tgtatcccag gaccaccctg ggcggggagg gctgaggtca 120 gggaggtctg aagctggtcc tgggctccgg gggtgacagt gatgaggaac tgggtgcaca 180 catgagtggg gcagccgggc ctggccagag aagcaacaca cacgtgcaca gacatgttta 240 tccacataca catgtgcacg catgtgcaca aacacattgc aggcaggcat gttgacgcct 300 caggcagcgg aggaccctga ctctgggccc tgctgacccg ggcaaggccc attgtgatgc 360 gtgccatgac ctcagaatgt cactggtgct tagcacctat ccgctctcca gactgcgtct 420 gtgttctacg gcagttacac acacgcagtg gtattcacaa gcggttttgt ggactcaaag 480 gttttctccc tgagaggcat aacccaggcc agctgattca tcagaatcag gtgagtgtga 540 cctgctctct tccctccagg ctgacttggg gacagtggct atggtatggg cggtgttggc 600 ctctgggcag ctacagagga gggtcatccc tgagcactca ccgggcgccc gttctacact 660 gcccatgtag acgattttct ctttcgtctt catggtggct tcgtagagtg ggtgctgttc 720 ccaaatgtac ccattcgaca ggtgagccgt ctggggtcag agaggcagta actggcctgg 780 gaatccagac aagaccctgg gttttgctct cagccctgct gtgtgccatg ctagacttca 840 ggcctcaacc ctgagacctc cctgctctag atcccaaatc tgcccagatt tccgatccaa 900 tgggcagagc ctggccctgg cagagacact gggatggatc cactgtgggt ggggaggagg 960 gaagggtcct cagaacacac ctggggccta agctgggtct tgatggtcac tgtgggaccc 1020 actggacaca cacagtccct tgtctgggag tggcatgggg agccttctgc ccttgggcag 1080 ttgtggaaag tgaaggagcc ctggagagct ggctgagggg agactatctt cccttgtgtt 1140 caaaggggtc caggcactgg ggctctcccc aagtatttct tattctgtct ggcctcgctt 1200 tccttttgcc ctgagtattc tcaggaggga cggtccatct agatgtcctc caggagcaag 1260 gacccactgt tcttcatcag tgacccagga aaatgaagcc ccctcctgtg gggacagctc 1320 agaatggtgg agtccacagt ccctccctga gagacatggt ttccatgagc acagtggctg 1380 ctttggagac agtaatcatt ttcatcccca aaaccaaaca cactcctgct caaatggtgt 1440 tattgctaaa gcagcttcac tggttagact gaagggccat ggtagcccaa gtgatgagcg 1500 gggtagaatg gagcagtcag gagagatctt gttccccgta ggaaactggg catctctgtg 1560 gccctgaaca tcccaggagg ccgatcgtac agagacctct ggtgcctgac cgcagttcac 1620 atccacatcc ctggaataga ccatcacagg ctcttcaccc ttggcaggtg gacaccattc 1680 aacctgccgg ggcaggatgg acatggtaga gaatgcagat agtttgcagg cacaggagcg 1740 gaaggacata cttatgaagt atgacaaggg acaccgagct gggctgccag aggacaaggg 1800 gcctgagccc gttggaatca acagcagcat tgatcgtttt ggcattttgc atgagacgga 1860 gctgcctcct gtgactgcac gggaggcgaa gaaaattcgg cgggagatga cacgaacgag 1920 caagtggatg gaaatgctgg gagaatggga gacatataag cacagtagca aactcataga 1980 tcgagtgtac aagggaattc ccatgaacat ccggggcccg gtgtggtcag tcctcctgaa 2040 cattcaggaa atcaagttga aaaaccccgg aagataccag atcatgaagg agaggggcaa 2100 gaggtcatct gaacacatcc accacatcga cctggacgtg aggacgactc tccggaacca 2160 tgtcttcttt agggatcgat atggagccaa gcagagggaa ctattctaca tcctcctggc 2220 ctattcggag tataacccgg aggtgggcta ctgcagggac ctgagccaca tcaccgcctt 2280 gttcctcctt tatctgcctg aggaggacgc attctgggca ctggtgcagc tgctggccag 2340 tgagaggcac tccctgccag gattccacag cccaaatggt gggacagtcc aggggctcca 2400 agaccaacag gagcatgtgg tacccaagtc acaacccaag accatgtggc atcaggacaa 2460 ggaaggtcta tgcgggcagt gtgcctcgtt aggctgcctt ctccggaacc tgattgacgg 2520 gatctctctc gggctcaccc tgcgcctgtg ggacgtgtat ttggtggaag gagaacaggt 2580 gttgatgcca ataaccagca ttgctcttaa ggttcagcag aagcgcctca tgaagacatc 2640 caggtgtggc ctgtgggcac gtctgcggaa ccaattcttc gatacctggg ccatgaacga 2700 tgacaccgtg ctcaagcatc ttagggcctc tacgaagaaa ctaacaagga agcaagggga 2760 cctgccaccc ccaggcccaa cagccctggg acgaaggtgt gtggcaggaa gcccccagcc 2820 agtctgaacc ctgggggcag tcccaggagc cacccaccat gccccaacgg cttccccatg 2880 ccaggcagca cacacccctc cctctgggat cagcagacta caggcgtgtc gtcagtgtca 2940 gaccacaggg gccacacaga gaccccaagg actccagaga tgcagccaaa cgcgagcaag 3000 ggtccttggc acccaggcct gtgccggctt cacgtggtgg gaagaccctc tgcaaggggt 3060 ataggcaggc ccctccaggc ccaccagccc agttccagcg gcccatttgc tcagcttccc 3120 cgccatgggc atctcgtttt tccacgccct gtcctggtgg ggctgtccgg gaagacacgt 3180 accctgtggg cactcagggt gtgcccagcc tggccctggc tcagggagga cctcagggtt 3240 cctggagatt cctggagtgg aagtcaatgc cccggctccc aacggacctg gatatagggg 3300 gcccttggtt cccccattat gattttgaac ggagctgctg ggtccgtgcc atatcccagg 3360 aggaccagct ggccacctgc tggcaggctg aacactgcgg agaggttcac aacaaagata 3420 tgagttggcc tgaggagatg tcttttacag caaatagtag taaaatagat agacaaaagg 3480 ttcccacaga aaagggagcc acaggtctaa gcaacctggg aaacacatgc ttcatgaact 3540 caagcatcca gtgcgttagt aacacacagc cactgacaca gtattttatc tcagggagac 3600 atctttatga actcaacagg acaaatccca ttggtatgaa ggggcatatg gctaaatgct 3660 atggtgattt agtgcaggaa ctctggagtg gaactcagaa gagtgttgcc ccattaaagc 3720 ttcggcggac catagcaaaa tatgctccca agtttgatgg gtttcagcaa caagactccc 3780 aagaacttct ggcttttctc ttggatggtc ttcatgaaga tctcaaccga gtccatgaaa 3840 agccatatgt ggaactgaag gacagtgatg gccgaccaga ctgggaagta gctgcagagg 3900 cctgggacaa ccatctaaga agaaatagat caattattgt ggatttgttc catgggcagc 3960 taagatctca agtcaaatgc aagacatgtg ggcatataag tgtccgattt gaccctttca 4020 attttttgtc tttgccacta ccaatggaca gttacatgga cttagaaata acagtgatta 4080 agttagatgg tactacccct gtacggtatg gactaagact gaatatggat gaaaagtaca 4140 caggtttaaa aaaacagctg agggatctct gtggacttaa ttcagaacaa atcctactag 4200 cagaagtaca tgattccaac ataaagaact ttcctcagga taaccaaaaa gtacaactct 4260 cagtgagcgg atttttgtgt gcatttgaaa ttcctgtccc ttcatctcca atttcagctt 4320 ctagtccaac acaaatagat ttctcctctt caccatctac aaatggaatg ttcaccctaa 4380 ctaccaatgg ggacctaccc aaaccaatat tcatccccaa tggaatgcca aacactgttg 4440 tgccatgtgg aactgagaag aacttcacaa atggaatggt taatggtcac atgccatctc 4500 ttcctgacag cccctttaca ggttacatca ttgcagtcca ccgaaaaatg atgaggacag 4560 aactgtattt cctgtcacct caggagaatc gccccagcct ctttggaatg ccattgattg 4620 ttccatgcac tgtgcatacc cagaagaaag acctatatga tgcggtttgg attcaagtat 4680 cctggttagc aagaccactc ccacctcagg aagctagtat tcatgcccag gatcgtgata 4740 actgtatggg ctatcaatat ccattcactc tacgagttgt gcagaaagat gggatctcct 4800 gtgcttggtg cccacagtat agattttgca gaggctgtaa aattgattgt ggggaagaca 4860 gagctttcat tggaaatgcc tatattgctg tggattggca ccccacagcc cttcaccttc 4920 gctatcaaac atcccaggaa agggttgtag ataagcatga gagtgtggag cagagtcggc 4980 gagcgcaagc cgagcccatc aacctggaca gctgtctccg tgctttcacc agtgaggaag 5040 agctagggga aagtgagatg tactactgtt ccaagtgtaa gacccactgc ttagcaacaa 5100 agaagctgga tctctggagg cttccaccct tcctgattat tcaccttaag cgatttcaat 5160 ttgtaaatga tcagtggata aaatcacaga aaattgtcag atttcttcgg gaaagttttg 5220 atccgagtgc ttttttggta ccacgagacc cggccctctg ccagcataaa ccactcacac 5280 cccaggggga tgagctctcc aagcccagga ttctggcaag agaggtgaag aaagtggatg 5340 cgcagagttc ggctggaaaa gaggacatgc tcctaagcaa aagcccatct tcactcagcg 5400 ctaacatcag cagcagccca aaaggttctc cttcttcatc aagaaaaagt ggaaccagct 5460 gtccctccag caaaaacagc agccctaata gcagcccacg gactttgggg aggagcaaag 5520 ggaggctccg gctgccccag attggcagca aaaataagcc gtcaagtagt aagaagaact 5580 tggatgccag caaagagaat ggggctgggc agatctgtga gctggctgac gccttgagcc 5640 gagggcatat gcgggggggc agccaaccag agctggtcac tcctcaggac catgaggtag 5700 ctttggccaa tggattcctt tatgagcatg aagcatgtgg caatggctgt ggcgatggct 5760 acagcaatgg tcagcttgga aaccacagtg aagaagacag cactgatgac caaagagaag 5820 acactcatat taagcctatt tataatctat atgcaatttc atgccattca ggaattctga 5880 gtgggggcca ttacatcact tatgccaaaa acccaaactg caagtggtac tgttataatg 5940 acagcagctg tgaggaactt caccctgatg aaattgacac cgactctgcc tacattcttt 6000 tctatgagca gcaggggata gactacgcac aatttctgcc aaagattgat ggcaaaaaga 6060 tggcagacac aagcagtacg gatgaagact ctgagtctga ttacgaaaag tactctatgt 6120 tacagtaaag ctaccactct ggctgctaga cagcttggtg gcgagggaga tgactccttg 6180 tagctgatac ttggcaaaag tgtcactgaa agacaagcta aatgtagtta ttttatcctg 6240 ttagaacaaa aattctaatt aaaatagtta acttgaagag tagaaacaat tgtattttga 6300 agtctcatac aagctgtctg atagagaact ttcaggcaga tcccaccatt agcctgtaaa 6360 caaaaggtgt ggcaccagcc acctgggacc aaataagaat tgaattgtgc ttgtccagat 6420 atgaacaaat atgtagtgag tatagagttt accaataatc ataacaaata ttaaagattt 6480 ccttggagtc agaggaaaaa acaaacaatt ataatgttgt ctagggacga catgatacgc 6540 tacctccttt ttcctgaagt tttattccat tatattgaca agatggagaa agcaagatca 6600 tgaaggtgtg caaatgattc ttacggcatg gacaaggatt tttcaattta ttttttaaac 6660 tgtttccata ccctttcttt ttcttgcttt ttgtttttgc cattgtgttt acgtttgaga 6720 cacaaccagt cattggtggc aggggcatag agtggtcagt ctgaaaggga ggctctctta 6780 agagctatgt gccttccaac cagagggaga cccagtagaa agaaaaacat cctgggaaat 6840 ccagctacca gggccctccc agtggaggca tcttacattt aggctacttc aagtatcctc 6900 agaaatgtat tctgcacccc cggccccgcc catgctgagg gaaggggagc agttgccaat 6960 atttgcacca tcttcacatg cacatgttgc aacaagagct tctgggaagg taagcggcat 7020 cggagctaga tcacgtttca caattagtgg ttattctttt ctgtgtttgt tttgcacttt 7080 aaaaaagaga gaacacatgc aaatgaactt gcttgtgtgt atttgatggc tctaagggct 7140 ataaattaca aacaaaacac atcccagaca ttaggagttc ataagtatat ttaatgaaat 7200 tggtggtttt aggaagtcaa ctttagtttt gctttgtttg catgtccact ggttttttta 7260 ttttgatatt tgtctttttt taaattttac agtagtcatt gaaagttatg tttctttgct 7320 tacttcattt tttccctcta attatttaag attggaacaa aagtataaat attatttatt 7380 tgaggtagaa tttttttcat gtagtttctt aatatatact tgaaggaaat gtttcacctt 7440 atttttggtc tttgtttatt catttagacc ctgcaagttg attctcattg ccagattcca 7500 ttaccctttc ttcctcatag gtagtaatta ccaatgtaac taagcatttg tgttctgata 7560 tctgaggcca gtaactatta atatctagtt ctcagagcat ttggaaaggt tatcttaaat 7620 ggctacctaa attgaaatcc ttttcagaaa aaatataatt gcaagtaggt aggagtggcc 7680 taaattgtct aatgtaataa agtcagacaa aatgcacact ttatagtttc aagattttca 7740 gtaaataaaa tctgtccatt cctacctgga catgtcccat taaaaagtgg aagattttaa 7800 ataatttctt tacagatgtt ttatttaaac aggtagcaca atctactaat gttgtgtgat 7860 ttgtgttata ctggttgtaa ttaatttttt taattcatga actagcggaa aatttattaa 7920 attaactatt aactacattc accttgtaaa ttactgtata aaacttgttg acaatgcact 7980 gactttagaa agatgttaat gtacataaat agagtgtaaa taaaatagtg ttgatgtact 8040 gaaatatgaa ctgtatcaaa agtattggta attgtatatg gggtgtacct gtttatctgt 8100 taactattat ccaaacaaat taaatactgt ggttgcctct atgtgctgtt tttcctcata 8160 caagtaaaca cagaaagtca aaaaaaaaaa aaaaaaaaaa a 8201 <210> 273 <211> 582 <212> DNA <213> HUMAN <400> 273 ttcccaccag gataatcccc ttttcaagag cgccaccacg acggtcatga accccaagtt 60 tgctgagagt taggagcact tggtgaagac aaggccgtca ggacccacca tgtctgcccc 120 atcacgcggc cgagacatgg cttgccacag ctcttgagga tgtcaccaat taaccagaaa 180 tccagttatt ttccgccctc aaaatgacag ccatggccgg ccgggtgctt ctgggggctc 240 gtcgggggga cagctccact ctgactggca cagtctttgc atggagactt gaggagggag 300 ggcttgaggt tggtgaggtt aggtgcgtgt ttcctgtgca agtcaggaca tcagtctgat 360 taaaggtggt gccaatttat ttacatttaa acttgtcagg gtataaaatg acatcccatt 420 aattatattg ttaatcaatc acgtgtatag aaaaaaaata aaacttcaat acaggctgtc 480 catggaaact gggcactgtg tccgctgtat tcccccgact ggcaaggtgg ccaggcacac 540 gtgggccctg tcctgcccgc tgacctttgc cacacaggca ca 582 <210> 274 <211> 109 <212> DNA <213> HUMAN <400> 274 cgtccctcag tcctctctca ggagtgcacg aagttcaagg tcagcagctg ccgggaatgc 60 atcgagtcgg ggcccggctg cacctggtgc cagaagctgg taagtgcct 109 <210> 275 <211> 201 <212> DNA <213> HUMAN <400> 275 ccctccccag aacttcacag ggccggggga tcctgactcc attcgctgcg acacccggcc 60 acagctgctc atgaggggct gtgcggctga cgacatcatg gaccccacaa gcctcgctga 120 aacccaggaa gaccacaatg ggggccagaa gcagctgtcc ccacaaaaag tgacgcttta 180 cctgcgacca ggtaggcttg g 201 <210> 276 <211> 240 <212> DNA <213> HUMAN <400> 276 cgtcttccag ggagggggct ctgcttctgc gggaagtgcc gctgccaccc gggctttgag 60 ggctcagcgt gccagtgcga gaggaccact gagggctgcc tgaacccgcg gcgtgttgag 120 tgtagtggtc gtggccggtg ccgctgcaac gtatgcgagt gccattcagg ctaccagctg 180 cctctgtgcc aggagtgccc cggctgcccc tcaccctgtg gcaagtacat gtgagtgcag 240 <210> 277 <211> 2016 <212> DNA <213> HUMAN <400> 277 ctaccatttt ccctctcgat tctatatgta cactcgggac aagttctcct gatcgaaaac 60 ggcaaaacta aggccccaag taggaatgcc ttagttttcg gggttaacaa tgattaacac 120 tgagcctcac acccacgcga tgccctcagc tcctcgctca gcgctctcac caacagccgt 180 agcccgcagc cccgctggac accggttctc catccccgca gcgtagcccg gaacatggta 240 gctgccatct ttacctgcta cgccagcctt ctgtgcgcgc aactgtctgg tcccgccccg 300 tcctgcgcga gctgctgccc aggcaggttc gccggtgcga gcgtaaaggg gcggagctag 360 gactgccttg ggcggtacaa atagcaggga accgcgcggt cgctcagcag tgacgtgaca 420 cgcagcccac ggtctgtact gacgcgccct cgcttcttcc tctttctcga ctccatcttc 480 gcggtagctg ggaccgccgt tcaggtaaga atggggcctt ggctggatcc gaagggcttg 540 tagcaggttg gctgcggggt cagaaggcgc ggggggaacc gaagaacggg gcctgctccg 600 tggccctgct ccagtcccta tccgaactcc ttgggaggca ctggccttcc gcacgtgagc 660 cgccgcgacc accatcccgt cgcgatcgtt tctggaccgc tttccactcc caaatctcct 720 ttatcccaga gcatttcttg gcttctctta caagccgtct tttctttact cagtcgccaa 780 tatgcagctc tttgtccgcg cccaggagct acacaccttc gaggtgaccg gccaggaaac 840 ggtcgcccag atcaaggtaa ggctgcttgg tgcgccctgg gttccatttt cttgtgctct 900 tcactctcgc ggcccgaggg aacgcttacg agccttatct ttccctgtag gctcatgtag 960 cctcactgga gggcattgcc ccggaagatc aagtcgtgct cctggcaggc gcgcccctgg 1020 aggatgaggc cactctgggc cagtgcgggg tggaggccct gactaccctg gaagtagcag 1080 gccgcatgct tggaggtgag tgagagagga atgttctttg aagtaccggt aagcgtctag 1140 tgagtgtggg gtgcatagtc ctgacagctg agtgtcacac ctatggtaat agagtacttc 1200 tcactgtctt cagttcagag tgattcttcc tgtttacatc cctcatgttg aacacagacg 1260 tccatgggag actgagccag agtgtagttg tatttcagtc acatcacgag atcctagtct 1320 ggttatcagc ttccacacta aaaattaggt cagaccaggc cccaaagtgc tctataaatt 1380 agaagctgga agatcctgaa atgaaactta agatttcaag gtcaaatatc tgcaactttg 1440 ttctcattac ctattgggcg cagcttctct ttaaaggctt gaattgagaa aagaggggtt 1500 ctgctgggtg gcaccttctt gctcttacct gctggtgcct tcctttccca ctacaggtaa 1560 agtccatggt tccctggccc gtgctggaaa agtgagaggt cagactccta aggtgagtga 1620 gagtattagt ggtcatggtg ttaggacttt ttttcctttc acagctaaac caagtccctg 1680 ggctcttact cggtttgcct tctccctccc tggagatgag cctgagggaa gggatgctag 1740 gtgtggaaga caggaaccag ggcctgatta accttccctt ctccaggtgg ccaaacagga 1800 gaagaagaag aagaagacag gtcgggctaa gcggcggatg cagtacaacc ggcgctttgt 1860 caacgttgtg cccacctttg gcaagaagaa gggccccaat gccaactctt aagtcttttg 1920 taattctggc tttctctaat aaaaaagcca cttagttcag tcatcgcatt gtttcatctt 1980 tacttgcaag gcctcaggga gaggtgtgct tctcgg 2016 <210> 278 <211> 1817 <212> DNA <213> HUMAN <400> 278 gccacggcgc ggacgccatg cacacggacc ctgactactc ggctgcctat gtcgtcatag 60 aaactgatgc agaagatgga atcaaggggt gtggaattac cttcactctg ggaaaaggca 120 ctgaagttga ttggtccaga aaagggcgtg gtgcacctgg cgacagcggc cgtcctaaac 180 gcggtgtggg acttgtgggc caagcaggag ggaaagcctg tctggaagtt acttgtggac 240 atggatccca ggatgctggt atcctgcata gatttcaggt acatcactga tgtcctgact 300 gaggaggatg ccctagaaat actgcagaaa ggtcaaattg gtaaaaaaga aagagagaag 360 caaatgctgg cacaaggata ccctgcttac acgacatcgt gcgcctggct ggggtactca 420 gatgacacgt tgaagcagct ctgtgcccag gcgctgaagg atggctggac caggtttaaa 480 gtaaaggtgg gtgctgatct ccaggatgac atgcgaagat gccaaatcat ccgagacatg 540 attggaccgg aaaagacttt gatgatggat gccaaccagc gctgggatgt gcctgaggcg 600 gtggagtgga tgtccaagct ggccaagttc aagccattgt ggattgagga gccaacctcc 660 cctgatgaca ttctggggca cgccaccatt tccaaggcac tggtcccatt aggaattggc 720 attgccacag gagaacagtg ccacaataga gtgatattta agcaactcct acaggcgaag 780 gccctgcagt tcctccagat tgacagttgc agactgggca gtgtcaatga gaacctctca 840 gtattgctga tggccaaaaa gtttgaaatt cctgtttgcc cccatgctgg tggagttggc 900 ctctgtgaac tggtgcagca cctgattata tttgactaca tatcagtttc tgcaagcctt 960 gaaaataggg tgtgtgagta tgttgaccac ctgcatgagc atttcaagta tcccgtgatg 1020 atccagcggg cttcctacat gcctcccaag gatcccggct actcaacaga aatgaaggag 1080 gaatctgtaa agaaacacca gtatccagat ggtgaagttt ggaagaaact ccttcctgct 1140 caagaaaatt aagtgctcag ccccaacaac ttttttcttt ctgaagtgaa agggcttaaa 1200 atttcttgga aatagtttta caaaaatgga tttaaaaaat cctaccgatc aagatgagtt 1260 cagctagaag tcataccacc ctcaggaatc agctaaagca aaaagaactt ttacctcggc 1320 atccagccca acccctaaag actgacaata tccttcaagc tcctttgaaa gcaccctaaa 1380 cagccatttc cattttaata gttggatgcg gattgtaccc ttcaatctga aagtcttcag 1440 ctttgaagtc atcaattttc tcaacttttc gaagaatcct gagctttggg aaaggtctgg 1500 gttctcgctg aagctaaaaa caaaataagg ccattatttt gccataattg tacgacctgt 1560 tgtaattgct cctcatgtcc atgaaacaag tacacaggat gtgatcaaca aagttctatt 1620 ttacaggagt atgatcctgt cgataccttg ccgtagttat gtaacatgat tggagcgcaa 1680 ccagctgttc tcttgaccac agatcgagag tgaggggtat tttgtgacat tacacagcat 1740 caggagcctg gtgcctcatc aggtgtaagt tcttataacc actcttggca aatttattaa 1800 agacaggaac acagtca 1817 <210> 279 <211> 3320 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(3320) <223> N=any base <400> 279 gctgcaggcg gccctggcca ggcttgacga tgaaatcgct cagaagaaca atgccctgaa 60 gaagatccgg gagctggagg gccacatctc agacctccag gaggacctgg actcagagcg 120 ggccgccagg aacaaggctg aaaagcagaa gcgagacctc ggcgaggagc tggaggccct 180 aaagacagag ctggaagaca cactggacag cacagccact cagcaggagc tcagggccaa 240 gagggagcag gaggtgacgg tgctgaagaa ggccctggat gaagagacgc ggtcccatga 300 ggctcaggtc caggagatga ggcagaaaca cgcacaggcg gtggaggagc tcacagagca 360 gcttgagcag ttcaagaggg ccaaggcgaa cctagacaag aataagcaga cgctggagaa 420 agagaacgca gacctggccg gggagctgcg ggtcctgggc caggccaagc aggaggtgga 480 acataagaag aagaagctgg aggcgcaggt gcaggagctg cagtccaagt gcagcgatgg 540 ggagcgggcc cgggcggagc tcaatgacaa agtccacaag ctgcagaatg aagttgagag 600 cgtcacaggg atgcttaacg aggccgaggg gaaggccatt aagctggcca aggacgtggc 660 gtccctcagt tcccagctcc aggacaccca ggagctgctt caagaagaaa cccggcagaa 720 gctcaacgtg tctacgaagc tgcgccagct ggaggaggag cggaacagcc tgcaagacca 780 gctggacgag gagatggagg ccaagcagaa cctggagcgc cacatctcca ctctcaacat 840 ccagctctcc gactcgaaga agaagctgca ggactttgcc agcaccgtgg aagctctgga 900 agaggggaag aagaggttcc agaaggagat cgagaacctc acccagcagt acgaggagaa 960 ggcggccgcg tatgataaac tggaaaagac caagaacagg cttcagcagg agctggacga 1020 cctggttgtt gatttggaca accagcggca actcgtgtcc aacctggaaa agaagcagag 1080 gaaatttgat cagttgttag ccgaggagaa aaacatctct tccaaatacg cggatgagag 1140 ggacagagct gaggcagaag ccagggagaa ggaaaccaag gccctgtccc tggctcgggc 1200 ccttgaagag gccttggaag ccaaagagga actcgagcgg accaacaaaa tgctcaaagc 1260 cgaaatggaa gacctggtca gctccaagga tgacgtgggc aagaacgtcc atgagctgga 1320 gaagtccaag cgggccctgg agacccagat ggaggagatg aagacgcagc tggaagagct 1380 ggaggacgag ctgcaagcca cggaggacgc caaactgcgg ctggaagtca acatgcaggc 1440 gctcaagggc cagttcgaaa gggatctcca agcccgggac gagcagaatg aggagaagag 1500 gaggcaactg cagagacagc ttcacgagta tgagacggaa ctggaagacg agcgaaagca 1560 acgtgccctg gcagctgcag caaagaagaa gctggaaggg gacctgaaag acctggagct 1620 tcaggccgac tctgccatca aggggaggga ggaagccatc aagcagctac gcaaactgca 1680 ggctcagatg aaggactttc aaagagagct ggaagatgcc cgtgcctcca gagatgagat 1740 ctttgccaca gccaaagaga atgagaagaa agccaagagc ttggaagcag acctcatgca 1800 gctacaagag gacctcgccg ccgctgagag ggctcgcaaa caagcggacc tcgagaagga 1860 ggaactggca gaggagctgg ccagtagcct gtcgggaagg aacgcactcc aggacgagaa 1920 gcgccgcctg gaggcccgga tcgcccagct ggaggaggag ctggaggagg agcagggcaa 1980 catggaggcc atgagcgacc gggtccgcaa agccacacag caggccgagc agctcagcaa 2040 cgagctggcc acagagcgca gcacggccca gaagaatgag agttcccggc agcagcttga 2100 gcggcagaac aaggagctcc ggagcaagct ccacgagatg gagggggccg tcaagtccaa 2160 gttcaaatcc accatcgcgg cgctggaggc caagattgca cagctagagg agcaggtcga 2220 gcaggaggcc agagagaaac aggcggccac caagtcgctg aagcagaaag acaagaagct 2280 gaaggaaatc ttgctgcagg tggaggacga gcgcaagatg gccgagcagt acaaggagca 2340 ggcagagaaa ggcaatgcca gggtcaagca gctcaagagg cagctggagg aggcagagga 2400 ggagtcccag cgcatcaacg ccaaccgcag gaagctgcag cgggagctgg atgaggccac 2460 ggagagcaac gaggccatgg gccgcgaggt gaacgcactc aagagcaagc tcaggcgagg 2520 aaacgagacc tctttcgttc cttctagaag gtctggagga cgtagagtta ttgaaaatgc 2580 agatggttct gaggaggaaa cggacactcg agacgcagac ttcaatggaa ccaaggccag 2640 tgaataagca actttctaca gttttgcacc acggcaagaa aaccaaaaac caaaacaaac 2700 aaacaaaaaa aaacccaaca acaacccaga acaaagcaaa acccagcaga ctgtacttag 2760 cattgtctaa atccattctc aaattccaaa tatcacagac ncctcacaca aggaatataa 2820 aaaccaccac cctccagcct gggcaacgta gtaaaacctc atctatacaa gaatttaaaa 2880 ataagctggg cgtggtggta cacacctgtg gtcccagcta ctagggaggc tgagccagga 2940 agaacgctcc agcccaggac ttcgaggctg caatgagcta taattgcatc attgcactcc 3000 agcctgggca acagagaccc tgtctcaacc accaccacca ccaccacccc tactacccct 3060 gtattcaagg taaaaattga agtttgtatg atgtaagaga tgagaaaaac ccaacaggaa 3120 acacagacac atcctccagt tctatcaatg gattgtgcag acactgagtt tttagaaaaa 3180 catatccacg gtaaccggtc cctggcaatt ctttttacat gaaatgggga gaaagtcacc 3240 gaaatgggtg ccgccggccc ccactcccaa ttcattccct aacctgcaaa cctttccaac 3300 ttctcacgtc aggcctttga 3320 <210> 280 <211> 1817 <212> DNA <213> HUMAN <400> 280 ctgtcagaat ggccaccatg gtaccatccg tgttgtggcc cagggcctgc tggactctgc 60 tggtctgctg tctgctgacc ccaggtgtcc aggggcagga gttccttttg cgggtggagc 120 cccagaaccc tgtgctctct gctggagggt ccctgtttgt gaactgcagt actgattgtc 180 ccagctctga gaaaatcgcc ttggagacgt ccctatcaaa ggagctggtg gccagtggca 240 tgggctgggc agccttcaat ctcagcaacg tgactggcaa cagtcggatc ctctgctcag 300 tgtactgcaa tggctcccag ataacaggct cctctaacat caccgtgtac gggctcccgg 360 agcgtgtgga gctggcaccc ctgcctcctt ggcagccggt gggccagaac ttcaccctgc 420 gctgccaagt ggagggtggg tcgccccgga ccagcctcac ggtggtgctg cttcgctggg 480 aggaggagct gagccggcag cccgcagtgg aggagccagc ggaggtcact gccactgtgc 540 tggccagcag agacgaccac ggagcccctt tctcatgccg cacagaactg gacatgcagc 600 cccaggggct gggactgttc gtgaacacct cagccccccg ccagctccga acctttgtcc 660 tgcccgtgac ccccccgcgc ctcgtggccc cccggttctt ggaggtggaa acgtcgtggc 720 cggtggactg caccctagac gggctttttc cagcctcaga ggcccaggtc tacctggcgc 780 tgggggacca gatgctgaat gcgacagtca tgaaccacgg ggacacgcta acggccacag 840 ccacagccac ggcgcgcgcg gatcaggagg gtgcccggga gatcgtctgc aacgtgaccc 900 tagggggcga gagacgggag gcccgggaga acttgacggt ctttagcttc ctaggaccca 960 ttgtgaacct cagcgagccc accgcccatg aggggtccac agtgaccgtg agttgcatgg 1020 ctggggctcg agtccaggtc acgctggacg gagttccggc cgcggccccg gggcagccag 1080 ctcaacttca gctaaatgct accgagagtg acgacggacg cagcttcttc tgcagtgcca 1140 ctctcgaggt ggacggcgag ttcttgcaca ggaacagtag cgtccagctg cgagtcctgt 1200 atggtcccaa aattgaccga gccacatgcc cccagcactt gaaatggaaa gataaaacga 1260 gacacgtcct gcagtgccaa gccaggggca acccgtaccc cgagctgcgg tgtttgaagg 1320 aaggctccag ccgggaggtg ccggtgggga tcccgttctt cgtcaacgta acacataatg 1380 gtacttatca gtgccaagcg tccagctcac gaggcaaata caccctggtc gtggtgatgg 1440 acattgaggc tgggagctcc cactttgtcc ccgtcttcgt ggcggtgtta ctgaccctgg 1500 gcgtggtgac tatcgtactg gccttaatgt acgtcttcag ggagcaccaa cggagcggca 1560 gttaccatgt tagggaggag agcacctatc tgcccctcac gtctatgcag ccgacagaag 1620 caatggggga agaaccgtcc agagctgagt gacgctggga tccgggatca aagttggcgg 1680 gggcttggct gtgccctcag attccgcacc aataaagcct tcaaactccc taaaaaaaaa 1740 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1800 aaaaaaaaaa aaaaaaa 1817 <210> 281 <211> 2099 <212> DNA <213> HUMAN <400> 281 gcgtgcaacc cgacgataga gagctcggag gtgatccaca aatccaagca cccagagatc 60 cattgggatc cttggcagat ggacatcagt gtcatttact aaccagcagg atggagacga 120 cgcccttgaa ttctcagaag cagctatcag cgtgtgaaga tggagaagat tgtcaggaaa 180 acggagttct acagaaggtt gttcccaccc caggggacaa agtggagtcc gggcaaatat 240 ccaatgggta ctcagcagtt ccaagtcctg gtgcgggaga tgacacacgg cactctatcc 300 cagcgaccac caccacccta gtggctgagc ttcatcaagg ggaacgggag acctggggca 360 agaaggtgga tttccttctc tcagtgattg gctatgctgt ggacctgggc aatgtctggc 420 gcttccccta catatgttac cagaatggag ggggggcatt cctcctcccc tacaccatca 480 tggccatttt tgggggaatc ccgctctttt acatggagct cgcactggga cagtaccacc 540 gaaatggatg catttcaata tggaggaaaa tctgcccgat tttcaaaggg attggttatg 600 ccatctgcat cattgccttt tacattgctt cctactacaa caccatcatg gcctgggcgc 660 tatactacct catctcctcc ttcacggacc agctgccctg gaccagctgc aagaactcct 720 ggaacactgg caactgcacc aattacttct ccgaggacaa catcacctgg accctccatt 780 ccacgtcccc tgctgaagaa ttttacacgc gccacgtcct gcagatccac cggtctaagg 840 ggctccagga cctggggggc atcagctggc agctggccct ctgcatcatg ctgatcttca 900 ctgttatcta cttcagcatc tggaaaggcg tcaagacctc tggcaaggtg gtgtgggtga 960 cagccacctt cccttatatc atcctttctg tcctgctggt gaggggtgcc accctccctg 1020 gagcctggag gggtgttctc ttctacttga aacccaattg gcagaaactc ctggagacag 1080 gggtgtggat agatgcagcc gctcagatct tcttctctct tggtccgggc tttggggtcc 1140 tgctggcttt tgctagctac aacaagttca acaacaactg ctaccaagat gccctggtga 1200 ccagcgtggt gaactgcatg acgagcttcg tttcgggatt tgtcatcttc acagtgctcg 1260 gttacatggc tgagatgagg aatgaagatg tgtctgaggt ggccaaagac gcaggtccca 1320 gcctcctctt catcacgtat gcagaagcga tagccaacat gccagcgtcc actttctttg 1380 ccatcatctt ctttctgatg ttaatcacgc tgggcttgga cagcacgttt gcaggcttgg 1440 agggggtgat cacggctgtg ctggatgagt tcccacacgt ctgggccaag cgccgggagc 1500 ggttcgtgct cgccgtggtc atcacctgct tctttggatc cctggtcacc ctgacttttg 1560 gaggggccta cgtggtgaag ctgctggagg agtatgccac ggggcccgca gtgctcactg 1620 tcgcgctgat cgaagcagtc gctgtgtctt ggttctatgg catcactcag ttctgcaggg 1680 acgtgaagga aatgctcggc ttcagcccgg ggtggttctg gaggatctgc tgggtggcca 1740 tcagccctct gtttctcctg ttcatcattt gcagttttct gatgagcccg ccacaactac 1800 gacttttcca atataattat ccttactgga gtatcatctt gggttactgc ataggaacct 1860 catctttcat ttgcatcccc acatatatag cttatcggtt gatcatcact ccagggacat 1920 ttaaagagcg tattattaaa agtattaccc cggagacacc aacagaaatt ccttgtgggg 1980 acatccgctt gaatgctgtg taacacactc accgagagga aaaaggcttc tccacaacct 2040 cctcctccag ttctgaggag gcacgcctgc cttctcccct ccgagtgaat gagtttgcc 2099 <210> 282 <211> 348 <212> DNA <213> HUMAN <400> 282 ggcctggagt gcgacggcaa ggtcaacatc tgctgtaaga aacagttctt tgtcagtttc 60 aaggacatcg gctggaatga ctggatcatt gctccctctg gctatcatgc caactactgc 120 gagggtgagt gcccgagcca tatagcaggc acgtccgggt cctcactgtc cttccactca 180 acagtcatca accactacgc atgcggccat agcccctttg ccaacctcaa atcgtgctgt 240 gtgcccacca agctgagacc catgtccatg ttgtactatg atgatggtca aaacatcatc 300 aaaaaggaca ttcagaacat gatcgtggag gagtgcgggt gctcctaa 348 <210> 283 <211> 2137 <212> DNA <213> HUMAN <400> 283 ctcgagagtt gccggggagg agcggagcgg tgcggaggct ctgctcggat cgaggtctgc 60 agcgcagctt cgggagcatg agtgctgcag tgactgcagg gaagctggca cgggcaccgg 120 ccgaccctgg gaaagccggg gtccccggag ttgcagctcc cggagctccg gcggcggctc 180 caccggcgaa agagatcccg gaggtcctag tggacccacg cagccggcgg cgctatgtgc 240 ggggccgctt tttgggcaag ggcggctttg ccaagtgctt cgagatctcg gacgcggaca 300 ccaaggaggt gttcgcgggc aagattgtgc ctaagtctct gctgctcaag ccgcaccaga 360 gggagaagat gtccatggaa atatccattc accgcagcct cgcccaccag cacgtcgtag 420 gattccacgg ctttttcgag gacaacgact tcgtgttcgt ggtgttggag ctctgccgcc 480 ggaggtctct cctggagctg cacaagagga ggaaagccct gactgagcct gaggcccgat 540 actacctacg gcaaattgtg cttggctgcc agtacctgca ccgaaaccga gttattcatc 600 gagacctcaa gctgggcaac cttttcctga atgaagatct ggaggtgaaa ataggggatt 660 ttggactggc aaccaaagtc gaatatgacg gggagaggaa gaagaccctg tgtgggactc 720 ctaattacat agctcccgag gtgctgagca agaaagggca cagtttcgag gtggatgtgt 780 ggtccattgg gtgtatcatg tataccttgt tagtgggcaa accacctttt gagacttctt 840 gcctaaaaga gacctacctc cggatcaaga agaatgaata cagtattccc aagcacatca 900 accccgtggc cgcctccctc atccagaaga tgcttcagac agatcccact gcccgcccaa 960 ccattaacga gctgcttaat gacgagttct ttacttctgg ctatatccct gcccgtctcc 1020 ccatcacctg cctgaccatt ccaccaaggt tttcgattgc tcccagcagc ctggacccca 1080 gcaaccggaa gcccctcaca gtcctcaata aaggcttgga gaaccccctg cctgagcgtc 1140 cccgggaaaa agaagaacca gtggttcgag agacaggtga ggtggtcgac tgccacctca 1200 gtgacatgct gcagcagctg cacagtgtca atgcctccaa gccctcggag cgtgggctgg 1260 tcaggcaaga ggaggctgag gatcctgcct gcatccccat cttctgggtc agcaagtggg 1320 tggactattc ggacaagtac ggccttgggt atcagctctg tgataacagc gtgggggtgc 1380 tcttcaatga ctcaacacgc ctcatcctct acaatgatgg tgacagcctg cagtacatag 1440 agcgtgacgg cactgagtcc tacctcaccg tgagttccca tcccaactcc ttgatgaaga 1500 agatcaccct ccttaaatat ttccgcaatt acatgagcga gcacttgctg aaggcaggtg 1560 ccaacatcac gccgcgcgaa ggtgatgagc tcgcccggct gccctaccta cggacctggt 1620 tccgcacccg cagcgccatc atcctgcacc tcagcaacgg cagcgtgcag atcaacttct 1680 tccaggatca caccaagctc atcttgtgcc cactgatggc agccgtgacc tacatcgacg 1740 agaagcggga cttccgcaca taccgcctga gtctcctgga ggagtacggc tgctgcaagg 1800 agctggccag ccggctccgc tacgcccgca ctatggtgga caagctgctg agctcacgct 1860 cggccagcaa ccgtctcaag gcctcctaat agctgccctc ccctccggac tggtgccctc 1920 ctcactccca cctgcatctg gggcccatac tggttggctc ccgcggtgcc atgtctgcag 1980 tgtgcccccc agccccggtg gctgggcaga gctgcatcat ccttgcaggt gggggttgct 2040 gtataagtta tttttgtaca tgttcgggtg tgggttctac agccttgtcc ccctccccct 2100 caaccccacc atatgaattg tacagaatat ttctatt 2137 <210> 284 <211> 817 <212> DNA <213> HUMAN <400> 284 agtcctgcgt ccgggccccg aggcgcagca gggcaccagg tggagcacca gctacgcgtg 60 gcgcagcgca gcgtccctag caccgagcct cccgcagccg ccgagatgct gcgaacagag 120 agctgccgcc ccaggtcgcc cgccggacag gtggccgcgg cgtccccgct cctgctgctg 180 ctgctgctgc tcgcctggtg cgcgggcgcc tgccgaggtg ctccaatatt acctcaagga 240 ttacagcctg aacaacagct acagttgtgg aatgagatag atgatacttg ttcgtctttt 300 ctgtccattg attctcagcc tcaggcatcc aacgcactgg aggagctttg ctttatgatt 360 atgggaatgc taccaaagcc tcaggaacaa gatgaaaaag ataatactaa aaggttctta 420 tttcattatt cgaagacaca gaagttgggc aagtcaaatg ttgtgtcgtc agttgtgcat 480 ccgttgctgc agctcgttcc tcacctgcat gagagaagaa tgaagagatt cagagtggac 540 gaagaattcc aaagtccctt tgcaagtcaa agtcgaggat attttttatt caggccacgg 600 aatggaagaa ggtcagcagg gttcatttaa aatggatgcc agctaatttt ccacagagca 660 atgctatgga atacaaaatg tactgacatt ttgttttctt ctgaaaaaaa tccttgctaa 720 atgtactctg ttgaaaatcc ctgtgttgtc aatgttctca gttgtaacaa tgttgtaaat 780 gttcaatttg ttgaaaatta aaaaatctaa aaataaa 817 <210> 285 <211> 2643 <212> DNA <213> HUMAN <400> 285 gcctccagct gacctctggc tcctgtcctc tggctccacc tgcaccgccc tgctcttcct 60 aaggggccag gaagccccca gaagctctac catcgacgtg ggtggtggca cccggctcac 120 cctgagagca gagggcgtgc agggggctca gttctgagcc cagccggccc accatggcac 180 ggcggttcca ggaggagctg gccgccttcc tcttcgagta tgacaccccc cgcatggtgc 240 tggtgcgtaa taagaaggtg ggcgttatct tccgactgat ccagctggtg gtcctggtct 300 acgtcatcgg gtgggtgttt ctctatgaga agggctacca gacctcgagc ggcctcatca 360 gcagtgtctc tgtgaaactc aagggcctgg ccgtgaccca gctccctggc ctcggccccc 420 aggtctggga tgtggctgac tacgtcttcc cagcccaggg ggacaactcc ttcgtggtca 480 tgaccaattt catcgtgacc ccgaagcaga ctcaaggcta ctgcgcagag cacccagaag 540 ggggcatatg caaggaagac agtggctgta cccctgggaa ggccaagagg aaggcccaag 600 gcatccgcac gggcaagtgt gtggccttca acgacactgt gaagacgtgt gagatctttg 660 gctggtgccc cgtggaggtg gatgacgaca tcccgcgccc tgcccttctc cgagaggccg 720 agaacttcac tcttttcatc aagaacagca tcagctttcc acgcttcaag gtcaacaggc 780 gcaacctggt ggaggaggtg aatgctgccc acatgaagac ctgcctcttt cacaagaccc 840 tgcaccccct gtgcccagtc ttccagcttg gctacgtggt gcaagagtca ggccagaact 900 tcagcaccct ggctgagaag ggtggagtgg ttggcatcac catcgactgg cactgtgacc 960 tggactggca cgtacggcac tgcagaccca tctatgagtt ccatgggctg tacgaagaga 1020 aaaatctctc cccaggcttc aacttcaggt ttgccaggca ctttgtggag aacgggacca 1080 actaccgtca cctcttcaag gtgtttggga ttcgctttga catcctggtg gacggcaagg 1140 ccgggaagtt tgacatcatc cctacaatga ccaccatcgg ctctggaatt ggcatctttg 1200 gggtggccac agttctctgt gacctgctgc tgcttcacat cctgcctaag aggcactact 1260 acaagcagaa gaagttcaaa tacgctgagg acatggggcc aggggcggct gagcgtgacc 1320 tcgcagctac cagctccacc ctgggcctgc aggagaacat gaggacatcc tgatgctcgg 1380 gccccaactc ctgactgggt gcagcgtgag gcttcagcct ggagccctgg tgggtcccag 1440 ccagggcaga ggggcctccc caggaagtct cctaccctct cagccaggca gagagcagtt 1500 tgccagaagc tcagggtgca tagtaggaga gacctgtgca aatctgagct ccggctccga 1560 ccccacacac cctgagggag gcctacccta gcctcagccg ctcctggtgg gggaatggct 1620 gggggttggg caggaccctc ccacacacct gcaccctagc ttcgtgcttc tctctccgga 1680 ctctcattat ccaacccgct gcctccattt ctctagatct gtgctctccg atgtggcagt 1740 cagtaaccat aggtgactaa attaaactaa aataaaatag aatgaaacac aaaattcaat 1800 tcctcggctg aactagccac atttcaactg ctcagtagat acgtgtggtt agtggctgcc 1860 atactggaca gctcggggca ttttcactgt caaagaaagt tctattagac agccctgctt 1920 gagccctgtt tcttcctggc ttcggtttcc ctggggaact tatcgacaat gcaagctcct 1980 gggcccaccc ccagacctcc tgaaccaaaa gctccagggc tggccgtatg atctgtgtgg 2040 atggcaaact ccccaggcca ttctgggacc taagtttaag aagtgccgtc ctcgaacttt 2100 ctgactctaa gctcctgagc gggagtcaga cttagccctg agcctgcact tcctgttcag 2160 gtgcagacac tgaacagggt ctcaaacacc ttcagcatgt gtgttgtgtg ctcacgtgcc 2220 acacagtgtc tcatgcacac aacccagtgt acacaccacc tacgtgcaca cagcatcctt 2280 ccacactgtg tatgtgaaca gcttgggccc tgcaaacaca accatctaca cacatctaca 2340 cccccaagca cacacacatg gtccgtgcca tgtcacctcc atagggaaag gcttctctcc 2400 aagtgtgcca ggccaggaca gccctcccag ccatgaatcc ttactcagct acctcgggtt 2460 ggggtgggag ccccagccaa atcctgggct ccctgcctgt ggctcagccc cagctcccaa 2520 ggcctgcctg gctctgtctg aacagaaggt ctgggggaag cgaggggtgg agtacaataa 2580 agggaatgag gacaaacaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2640 aaa 2643 <210> 286 <211> 1587 <212> DNA <213> HUMAN <400> 286 tggcactagg ggcagccact cagcccttcg agctgtaggg gaggcgctgc gcccccggcc 60 ccagccgatc gggggctcct ggcgctactg ccctccagag tccctcctgc cgtctgactt 120 gagtccctgc tgctgcagtg cacgcccccc tttcggcagc cagggtgggg cccagaccca 180 acctggcccc tcctgccccc accccgcctt tgggtcgctg acccccaggc tgtggtgagg 240 gtctgagagc tggtaccacg gagcctgggc aacctcctcc gcccacccat gcccaccccg 300 catgaggctg agaagcagat cacagggcca gaggaggcgg accggccccc ttcaatgtcc 360 agtcatgata cagcctctcc agcggccccc agccgcaacc cctgctgcct gtgctggtgc 420 tgctgctgta gctgctcctg gaaccaagag cggcggcgcg cgtggcaggc ctcccgggag 480 agcaagctgc agcccctccc cagctgtgaa gtatgtgcca cgccaagtcc tgaggaggtg 540 cagagctggg cgcagtcttt tgacaagctg atgcacagcc cagcgggacg cagcgtgttc 600 cgggcgttcc tgcggacaga gtacagcgag gagaacatgc tcttctggtt ggcctgcgag 660 gagctgaagg ccgaggccaa ccagcatgtg gtagacgaga aggcgaggct catctacgag 720 gactacgtat ccatcctgtc ccccaaggag gtgagcctgg actcccgtgt gcgggagggc 780 atcaacaaga agatgcagga gccgtccgca cacacgttcg acgacgcgca gctgcagatc 840 tacacgctca tgcaccggga ctcctacccc cgcttcctca gctctcccac ctaccgtgcc 900 ctgctgctgc aggggccatc acagtcctcc tccgaggcct aggccgcccc cagcagcaca 960 gaccccgccg cctcctacgg ccgactctgg gttcccttca ggtgttggtg tcggcagggc 1020 tgtcagggca catgcctggc cggctggggt ccccacccgc ggagacggtc ctagacccag 1080 tggggagtgc tgtgtctcct gggtctgccc acccgtggcc aagcaggaac tccaggtgca 1140 gggcgggcct ccaggtgcag ggcgggccag aagccccctc atcggcccgc agctggctgg 1200 cccagtgctc ctggctgggg gctcttgcgt ggtgagagta ggggtccccc caggagccat 1260 gctggaccca tgagcctcgc tggggcctcc tccccaggca gccaatgggc cccagacaag 1320 cctttggtgg ggaacagaac ctccgcatcg tgtagttttg tgacataagg agacctccta 1380 cttgagctgt ctgtacccca gaatcaaaca cagaactcag aaccagattt aggccctcag 1440 aatcctgcac tcaaggtggc aggacccaat ttctgtttta tatgttcatg aactttaaac 1500 ctggaaacat gtccttacta ggtgttttat caaaaaaaag ttttttatta ttgaagatat 1560 ttttaaagca aaaaaaaaaa aaaaaaa 1587 <210> 287 <211> 1163 <212> DNA <213> HUMAN <400> 287 gcgcggagcg ggctccggag ggaagtcccg agacaaaggg aagcgccgcc gccgccgccc 60 cgctcggtcc tccacctgtc cgctacgctc gccggggctg cggccgcccg agggactttg 120 aacatgtcgg ggatcgccct cagcagactc gcccaggaga ggaaagcatg gaggaaagac 180 cacccatttg gtttcgtggc tgtcccaaca aaaaatcccg atggcacgat gaacctcatg 240 aactgggagt gcgccattcc aggaaagaaa gggactccgt gggaaggagg cttgtttaaa 300 ctacggatgc ttttcaaaga tgattatcca tcttcgccac caaaatgtaa attcgaacca 360 ccattatttc acccgaatgt gtacccttcg gggacagtgt gcctgtccat cttagaggag 420 gacaaggact ggaggccagc catcacaatc aaacagatcc tattaggaat acaggaactt 480 ctaaatgaac caaatatcca agacccagct caagcagagg cctacacgat ttactgccaa 540 aacagagtgg agtacgagaa aagggtccga gcacaagcca agaagtttgc gccctcataa 600 gcagcgacct tgtggcatcg tcagaaggaa gggattggtt tggcaagaac ttgtttacaa 660 catttttgca aatctaaagt tgctccatac aatgactagt cacctggggg ggttgggcgg 720 gcgccatctt ccattgccgc cgcgggtgtg cggtctcgat tcgctgaatt gcccgtttcc 780 atacagggtc tcttccttcg gtcttttgta tttttgattg ttatgtaaaa ctcgctttta 840 ttttaatatt gatgtcagta tttcaactgc tgtaaaatta taaactttta tacttgggta 900 agtcccccag gggcgagttc ctcgctctgg gatgcaggca tgcttctcac cgtgcagagc 960 tgcacttggc ctcagctggc tgtatggaaa tgcaccctcc ctcctgccgc tcctctctag 1020 aaccttctag aacctgggct gtgctgcttt tgagcctcag accccagggc agcatctcgg 1080 ttctgcgcca cttcctttgt gtttatatgg cgttttgtct gtgttgctgt ttagagtaaa 1140 taaactgttt atataaaaaa aaa 1163 <210> 288 <211> 1075 <212> DNA <213> HUMAN <400> 288 aagcattgag tttactgcaa ggtcagaaaa gcatgcaaag cccttagagt ggctgcaaag 60 agctccaaca aaacaattta gaactttatt aaggaatagg gggaagctag gaagaaactc 120 aaaacatcaa gattttaaat acgcttcttg gtctccttgc tataattatc tgggataagc 180 atgctgtttt ctgtctgtcc ctaacatgcc ctgtgattat ccgcaaacaa cacacccaag 240 ggcagaactt tgttacttaa acaccatcct gtttgcttct ttcctcagga actgtggctg 300 caccatctgt cttcatcttc ccgccatctg atgagcagtt gaaatctgga actgcctctg 360 ttgtgtgcct gctgaataac ttctatccca gagaggccaa agtacagtgg aaggtggata 420 acgccctcca atcgggtaac tcccaggaga gtgtcacaga gcaggacagc aaggacagca 480 cctacagcct cagcagcacc ctgacgctga gcaaagcaga ctacgagaaa cacaaagtct 540 acgcctgcga agtcacccat cagggcctga gctcgcccgt cacaaagagc ttcaacaggg 600 gagagtgtta gagggagaag tgcccccacc tgctcctcag ttccagcctg accccctccc 660 atcctttggc ctctgaccct ttttccacag gggacctacc cctattgcgg tcctccagct 720 catctttcac ctcacccccc tcctcctcct tggctttaat tatgctaatg ttggaggaga 780 atgaataaat aaagtgaatc tttgcacctg tggtttctct ctttcctcat ttaataatta 840 ttatctgttg ttttaccaac tactcaattt ctcttataag ggactaaata tgtagtcatc 900 ctaaggcgca taaccattta taaaaatcat ccttcattct attttaccct atcatcctct 960 gcaagacagt cctccctcaa acccacaagc cttctgtcct cacagtcccc tgggccatgg 1020 taggagagac ttgcttcctt gttttcccct cctcagcaag ccctcatagt ccttt 1075 <210> 289 <211> 8096 <212> DNA <213> HUMAN <400> 289 cttttctcaa gacaactaca taagcagaca aaattgcaaa gatctgccct gtgtcgagta 60 tgacagccac gactcgtggc tctccggtcg gagggaatga caaccagggc caggctcctg 120 atggacagtc tctgcccccc ctccaacaga atcagacttc atcgcctgat tcttccaatg 180 aaaattcccc ggcaactccc ccagatgagc aaggtcaagg tgatgcccca ccacagcttg 240 aagatgagga acctgcattt ccacatactg acttggccaa gttggatgac atgatcaaca 300 ggcctcgatg ggtggttcca gttttgccga aaggggaatt agaagtgctt ttagaagctg 360 ctattgatct tagtaaaaag ggccttgatg ttaaaagtga agcatgtcag cgatttttcc 420 gtgatgggct aacaatatca ttcactaaaa ttcttacaga tgaagcagtg agtggctgga 480 agtttgaaat tcataggtgt ctggtggagc tatgtgtggc caagttgtcc caagactggt 540 ttccactttt agaacttctt gccatggcct taaatcctca ttgcaaattc catatctaca 600 atggtacacg tccatgtgaa tcagtttcct caagtgttca gttgcctgaa gatgaactct 660 ttgctcgttc tccagatcct cgatcaccaa agggttggct agtggatctt ctcaacaaat 720 ttggcacttt aaatgggttc cagattttgc atgatcgttt tattaatgga tcagcattaa 780 acgttcaaat aattgcagcc cttattaaac catttgggca atgctatgag tttctcactc 840 ttcatacagt gaaaaagtac tttcttccaa taatagaaat ggttccacag tttttagaaa 900 acttaactga tgaagaactg aaaaaagaag caaagaatga agccaaaaat gatgctcttt 960 caatgattat taaatctttg aagaatttag cttcaagggt tccaggacaa gaagaaactg 1020 ttaaaaactt agaaatattt aggttaaaaa tgatacttag attattgcaa atttcttctt 1080 tcaatggaaa gatgaatgca ctgaatgaag ttaataaggt gatatctagt gtatcatact 1140 atactcatcg acatggtaat cctgaggagg aagagtggct cacagctgaa cgaatggcag 1200 aatggataca gcagaacaat atcttatcca tagtgttgcg agatagtctt catcagccac 1260 agtatgtaga aaagttagag aagattcttc gttttgtcat caaagaaaaa gctctgacct 1320 tacaggatct tgataatatc tgggcagcac aggcagggaa acatgaagcc attgtgaaga 1380 atgtacatga tctcctggca aaattggcat gggatttttc tcctgaacaa cttgatcatc 1440 cttttgattg ttttaaggcc agtcggacaa atgcgagtaa aaagcaacgt gaaaagctac 1500 ttgagctgat acgtcgtctt gcagaagatg ataaagatgg tgtgatggca cacagagtgt 1560 tgaaccttct gtggaatctg gctcacagtg atgatgtgcc tgtagatatc atggacctgg 1620 ctctcagtgc ccacataaaa atactagatt acagttgctc ccaggaccgt gatacacaaa 1680 agatccaatg gatagatcgc tttatagaag aacttcgcac aaatgacaaa tgggttattc 1740 ccgcactgaa acaaattaga gaaatttgta gtttgtttgg tgaagcgcct caaaatttga 1800 gtcaaactca gcgaagtccc catgtgtttt atcgccatga cttaatcaat caacttcaac 1860 acaatcatgc cctagttact ttggtagcag aaaaccttgt aacttacatg gaaagcatga 1920 gactatatgc tagagaccat gaagattatg acccacaaac tgtgaggctg ggaagtagat 1980 atagtcatgt tcaagaagtt caagaacggc ttaacttcct tagattttta ttgaaggatg 2040 gtcagctgtg gctatgtgct cctcaggcaa aacaaatatg gaaatgctta gctgagaatg 2100 cagtttacct ttgtgatcgt gaagcctgtt ttaagtggta ttccaagttg atgggggatg 2160 aaccagactt agatcctgat attaataagg acttctttga aagtaatgtg cttcagcttg 2220 atccttctct gttaactgaa aatggaatga agtgttttga gcgattcttc aaagctgtga 2280 attgtcgaga aggaaaacta gtagcaaaaa ggagagccta tatgatggat gacttggagt 2340 taataggatt agattacctt tggagggtcg tgattcagag taatgatgat attgccagca 2400 gagctataga tctcctcaaa gagatataca cgaaccttgg tccaagacta caagtcaatc 2460 aggtggtgat ccatgaagac ttcattcagt cttgttttga tcgtctgaag gcttcctatg 2520 acacattgtg tgttttggat ggtgacaaag acagtgttaa ttgtgcaaga caggaagctg 2580 ttcgaatggt tcgagtatta actgttttaa gggaatatat aaatgaatgt gacagtgatt 2640 atcatgagga aagaacaatt ctccctatgt cgagagcatt ccgcggtaaa cacctctctt 2700 ttgtagttcg atttccaaac cagggcagac aggttgatga cttggaggta tggtctcata 2760 caaatgatac aattggttca gtacgacgat gtattctcaa tcgtattaaa gccaacgtag 2820 cccatacaaa aattgagctc tttgtgggcg gtgagctgat agatcctgca gatgatagaa 2880 agttgattgg acaattaaac ttaaaagata aatcgcttat tacagccaaa cttacacaga 2940 taagttccaa tatgccttca agccctgata gctcttctga ttcctccact ggatctcctg 3000 gaaaccatgg taatcattac agtgatggtc ccaatccaga agtggaaagc tgtttgcctg 3060 gagtgataat gtcactgcat cccagataca tctcttttct ttggcaagtt gcagacttag 3120 gtagcagcct aaatatgcca ccccttagag atggagcaag agtacttatg aaacttatgc 3180 cgccagatag cacaacgata gaaaaattaa gagctatttg tttagaccat gccaaacttg 3240 gagaaagcag ccttagtcca tctcttgact cacttttctt tggtccttca gcctcacaag 3300 tgctatatct aacagaggta gtctatgcct tgttaatgcc tgctggtgca cctctggctg 3360 atgattcctc tgattttcag tttcacttct tgaaaagtgg tggcctaccc cttgtactga 3420 gtatgctaac cagaaataac ttcctaccga atgcagatat ggaaactcga aggggtgcct 3480 acctcaatgc tcttaaaata gccaagcttt tgctaactgc cattggctat ggtcatgttc 3540 gagctgtggc agaagcttgt cagccaggtg tagaaggtgt gaatcccatg acacagatca 3600 accaagttac ccatgatcaa gcagtggtgc tacaaagtgc ccttcagagc attcctaatc 3660 catcatccga gtgcatgctt agaaatgtgt cagttcgtct tgctcagcag atatctgatg 3720 aggcttcaag atatatgcct gatatttgtg taattagagc tatacaaaaa attatctggg 3780 catcaggatg tgggtcgtta cagctagtat ttagcccaaa tgaagaaatc actaaaattt 3840 atgagaagac caatgcaggc aatgagccag acttggaaga cgaacaggtt tgctgtgaag 3900 cattggaagt gatgacctta tgttttgcct tgattccaac agccttagat gctcttagta 3960 aagaaaaggc ttggcagaca ttcatcattg acttactatt gcactgtcac agcaaaactg 4020 ttcgtcaggt ggcacaggag cagttctttt taatgtgcac cagatgttgc atgggacacc 4080 ggcctctact tttcttcatt actctactct ttactgtttt ggggagcaca gcaagagaga 4140 gagctaaaca ctcaggcgac tactttactc ttttaagaca ccttcttaat tacgcttaca 4200 atagtaatat taatgtaccc aatgctgaag ttcttttcaa taatgaaatt gattggctta 4260 aaagaattag ggatgatgtt aaaagaacag gagaaacggg tattgaagag acgatcttag 4320 agggccacct tggagtgaca aaggagttac tggcctttca aacttctgag aaaaaatttc 4380 atattggttg tgaaaaagga ggtgctaatc tcattaaaga attaattgat gatttcatat 4440 ttcctgcatc caatgtttac ctacagtata tgagaaatgg agagcttcca gctgaacagg 4500 ctattccggt ctgtggttca ccacctacaa ttaatgctgg ttttgaatta cttgtagcat 4560 tagctgttgg ctgtgtgagg aatctcaaac aaatagtaga ttctttgact gaaatgtatt 4620 acattggcac agcaataact acttgtgaag cacttactga gtgggaatat ctgccacctg 4680 ttggaccccg cccacccaaa ggattcgtgg ggctgaaaaa tgccggtgct acttgttaca 4740 tgaattctgt gattcagcaa ctctacatga ttccttccat taggaacggt attcttgcca 4800 ttgaaggcac aggtagtgat gtagatgatg atatgtctgg ggatgagaag caggacaatg 4860 agagcaatgt tgatcccagg gatgatgtat ttggatatcc tcaacaattt gaagataaac 4920 cagcattaag taaaactgaa gatagaaaag agtacaacat tggtgtccta agacaccttc 4980 aggtcatctt tggtcattta gctgcttctc gactgcaata ctatgtgccc agaggatttt 5040 ggaaacagtt caggctttgg ggtgagcctg ttaatctgcg tgaacaacac gatgctttag 5100 aattttttaa ttcattggtg gatagtttag atgaagcttt aaaagcttta ggacatccag 5160 ctatgctaag taaagtctta ggaggttcct ttgctgatca gaagatctgc caaggctgcc 5220 cacataggta cgaatgtgaa gaatctttta cgaccctaaa cgtagacatt agaaatcacc 5280 aaaatcttct tgattctttg gaacagtatg tcaaaggaga tttactagaa ggtgcaaatg 5340 catatcattg tgaaaaatgc aataaaaagg ttgataccgt aaagcgcttg ctgattaaaa 5400 aattacctcc tgttcttgct atacaactaa agcgatttga ctatgactgg gaaagagaat 5460 gtgcaatcaa gttcaatgat tattttgaat ttcctcgaga gctggacatg gaaccttaca 5520 cagttgcagg tgtcgcaaag ctggaagggg ataatgtaaa cccagagagt cagttgatac 5580 aacagagtga gcagtctgaa agtgagacag caggaagcac aaaatacaga cttgtgggtg 5640 tgctcgtaca cagtggtcaa gcgagtgggg ggcattatta ttcttacatc atccaaagga 5700 atggtggaga tggtgagaga aatcgctggt ataaatttga tgatggtgat gtaacagaat 5760 gtaaaatgga tgatgacgaa gaaatgaaaa accagtgttt tggtggagag tacatgggag 5820 aagtgtttga tcacatgatg aagcgtatgt catacaggcg ccagaaaagg tggtggaatg 5880 cttatatacc tttttatgaa cgaatggaca caatagacca agatgatgag ttgataagat 5940 atatatcaga gcttgctatc accaccagac ctcatcagat tattatgcca tcagccattg 6000 agagaagtgt acggaaacag aacgtacaat tcatgcataa ccgaatgcag tacagtatgg 6060 agtattttca gtttatgaaa aaactgctta catgtaatgg cgtttactta aaccctcctc 6120 ccgggcaaga tcacctgttg cctgaagcag aagaaatcac tatgatcagt attcaacttg 6180 ctgctaggtt cctctttact acaggatttc acacaaagaa agtagtccgt ggctctgcca 6240 gtgattggta tgatgcattg tgtattctcc ttcgtcacag caagaatgta cgtttttggt 6300 ttgctcataa cgtccttttt aatgtttcaa atcgcttctc cgaatacctt ctggagtgcc 6360 ctagtgcaga agtgaggggt gcgtttgcaa aacttatagt ctttattgca catttttcct 6420 tgcaagatgg gccatgtcct tcaccttttg cctctcctgg accttctagt caggcttatg 6480 acaacttaag cttgagtgat cacttactaa gagcagtact aaatctcttg agaagggaag 6540 tttcagagca tgggcgtcat ttacagcagt atttcaacct gtttgtaatg tatgccaatt 6600 taggtgtggc agagaagaca cagcttctga aattgagtgt acctgctact tttatgcttg 6660 tgtctttaga tgaaggtcca ggtcctccaa tcaaatacca gtatgctgaa ttaggcaaat 6720 tatactcagt agtgtcacag ctgatccgct gttgcaatgt ctcttcaaga atgcagtctt 6780 caatcaatgg taatcctcct cttcccaatc cttttggtga tcctaattta tcacaaccta 6840 taatgccaat tcagcagaat gtggcagaca ttttatttgt gagaacaagt tatgtgaaga 6900 aaatcattga agactgcagt aattcagagg aaaccgtcaa attgcttcgt ttttgctgct 6960 gggagaatcc tcagttctca tctactgtcc tcagtgaact tctctggcag gttgcatatt 7020 cctatcccta tgaactgcgg ccctatttgg atctgctttt gcaaatctta ctgattgagg 7080 actcctggca aactcacaga attcataatg cactgaaagg aattccagat gaccgagatg 7140 ggctgtttga cacaatccag cgctctaaga atcactatca aaaaagagca taccagtgta 7200 taaaatgtat ggtagctcta tttagtaact gtcctgttgc ttaccaaatc ctgcagggca 7260 atggagatct taaaagaaag tggacctggg cagtggaatg gcttggagat gaacttgaaa 7320 gaagaccata tactggcaat cctcagtaca cttacaacaa ttggtctccc ccagtgcaaa 7380 gcaatgaaac gtccaatggt tatttcttgg agagatcaca tagtgctagg atgacacttg 7440 caaaagcttg tgaactctgt ccagaggagg agccagatga ccaagatgct ccagatgaac 7500 atgagtcgcc tccacctgaa gatgccccat tgtaccccca ttcacctgga tctcagtatc 7560 aacagaataa ccatgtgcat ggacagccat atacaggccc agcagcacat cacatgaaca 7620 accctcagag aactggccaa cgagcacaag aaaattatga aggcagtgaa gaagtatccc 7680 cacctcaaac caaggatcaa tgaaatgcac ataattaact ggttccatca agactgtgca 7740 cccaggcctt acagtccaac ctttttctgt gtctggctaa tatttaaaac tagaaaaact 7800 attcctaatc aacatggagt ggagagttta ttcactgtct tatctgcaga aatttgctgt 7860 caatatataa cccgcctgca gtggaaagtg tatagtgttt tgtaataaat ggcctgatgc 7920 taatgtgtaa atggcaaagg tgtatatagt atattaatgt tgactgttaa ttcttaagca 7980 agaaactttt ttcttgatga gactcacaga tctacacaaa ctacaaaagt taattttctg 8040 ttacacccac tgcactctta accagtgttg ctgcctcatg gcagtggatc agctcc 8096 <210> 290 <211> 2454 <212> DNA <213> HUMAN <400> 290 ccaggaggca cgctggtttt ccggggccgc tccatcgcgc cttcctcctg cgcctcgctt 60 ctccggtcca gccgccatct tcctttccgc acaggggccg ccgagcgggg ccatgcagcc 120 aacgctgctt ctcagcctcc tgggagccgt ggggctggcg gctgtcaatt ccatgccagt 180 ggataacagg aaccacaatg aaggaatggt gactcgctgc atcattgagg tcctctcaaa 240 tgccttgtcg aagtccagcg ctccacccat cacccctgag tgccgccaag tcctgaagac 300 gagtagaaaa gacgtcaaag acaaagagac aactgaaaat gaaaacacaa agtttgaagt 360 aagattgtta agagacccag ctgatgcctc ggaagcccac gagtcctcca gcaggggaga 420 ggcaggagcc ccaggggagg aggacatcca aggcccaaca aaggcagaca cagagaaatg 480 ggcagaggga ggcgggcaca gccgagagcg agcggatgag ccccagtgga gcctctatcc 540 ctccgacagc caagtctctg aagaagtgaa gacacgccat tctgagaaga gccagagaga 600 ggatgaggag gaggaggagg gagagaacta tcaaaaaggg gagcgagggg aagatagcag 660 tgaagagaaa caccttgaag agccaggaga gacacaaaac gcttttctca atgaaagaaa 720 gcaggcttca gctataaaaa aagaggagtt agtggccaga tcggaaacac atgctgccgg 780 gcattctcag gagaagacac atagccgaga gaagagtagc caggagagtg gagaggaggc 840 agggagccag gagaatcacc cccaggagtc taaaggccaa ccccgaagcc aggaagaatc 900 tgaggaaggt gaggaagatg ccacctctga ggtggacaaa cgacgcacga ggcccagaca 960 ccaccacggg aggagcaggc ccgacaggtc ctctcaagga gggagtcttc cctctgagga 1020 aaagggacac ccccaggagg aatctgagga gtcaaacgtc agcatggcca gtttagggga 1080 aaagagggac caccattcaa cccactacag ggcttcagag gaagaacctg aatatggaga 1140 agaaataaag ggttatccag gcgtccaggc ccctgaggac ctggagtggg agcgctatag 1200 gggcagagga agtgaagaat acagggctcc aagacctcag agtgaggaga gttgggatga 1260 ggaggacaag agaaactacc ccagcttaga gcttgataag atggcacatg gatatggtga 1320 agaaagtgag gaagagaggg gccttgagcc gggaaaggga cgccatcaca gaggcagggg 1380 aggggagcca cgtgcctatt tcatgtctga caccagagaa gagaaaaggt tcttgggtga 1440 aggacaccac cgtgtccaag aaaaccagat ggacaaggca aggaggcatc cacaaggtgc 1500 gtggaaagag ctggacagaa attatctcaa ctacggtgag gaaggagccc cagggaagtg 1560 gcagcagcag ggagacctgc aggacactaa agaaaacagg gaggaagcta ggtttcaaga 1620 taaacaatat agctcccatc acacagctga aaagaggaag agattagggg aactgttcaa 1680 cccatactac gaccctctcc agtggaagag cagccatttt gaaagaagag acaacatgaa 1740 tgacaatttt ctcgagggtg aggaggaaaa tgagctgacc ttgaacgaga agaatttctt 1800 cccagaatac aactatgact ggtgggagaa aaagcccttc tctgaggatg tgaactgggg 1860 gtatgagaag agaaacctcg ccagggtccc caagctggac ctgaaaaggc aatatgacag 1920 ggtggcccaa ctggaccagc tccttcacta caggaagaag tcagctgagt ttccagactt 1980 ctatgattct gaggagccgg tgagcaccca ccaggaggca gaaaatgaaa aggacagggc 2040 tgaccagaca gtcctgacag aggacgagaa aaaagaactc gaaaacttgg ctgcaatgga 2100 tttggaacta cagaagatag ctgagaaatt cagccaaagg ggctgactgt cattggagcg 2160 gtgggcactg ttaagaagca gccatcacat gatctgtttt tcaccacttc actgaaagac 2220 accatttata tacccaaggg cagaaagtag aacttactat tcattaaatg tttgacacaa 2280 ttggaattgt ctttaatttc tgtcagaatg ctattgaaaa tgtgaattgc atgacttgta 2340 gcatattctt ttctgcaaaa tagacatatt aacatgctta tgacaatgac tgtgctactg 2400 tctttggaaa aatgtttgtc tcagttggaa ataataaaag attcacctga gacc 2454 <210> 291 <211> 3923 <212> DNA <213> HUMAN <400> 291 cccggacgct cgcgggtctc ggaacgcatc ccgccgcggg ggcttcggcc gtggcatggg 60 cgccgcgggc ctgctcgggg ttttcttggc tctcgtcgca ccgggggtcc tcgggatttc 120 ttgtggctct cctccgccta tcctaaatgg ccggattagt tattattcta cccccattgc 180 tgttggtacc gtgataaggt acagttgttc aggtaccttc cgcctcattg gagaaaaaag 240 tctattatgc ataactaaag acaaagtgga tggaacctgg gataaacctg ctcctaaatg 300 tgaatatttc aataaatatt cttcttgccc tgagcccata gtaccaggag gatacaaaat 360 tagaggctct acaccctaca gacatggtga ttctgtgaca tttgcctgta aaaccaactt 420 ctccatgaac ggaaacaagt ctgtttggtg tcaagcaaat aatatgtggg ggccgacacg 480 actaccaacc tgtgtaagtg ttttccctct cgagtgtcca gcacttccta tgatccacaa 540 tggacatcac acaagtgaga atgttggctc cattgctcca ggattgtctg tgacttacag 600 ctgtgaatct ggttacttgc ttgttggaga aaagatcatt aactgtttgt cttcgggaaa 660 atggagtgct gtccccccca catgtgaaga ggcacgctgt aaatctctag gacgatttcc 720 caatgggaag gtaaaggagc ctccaattct ccgggttggt gtaactgcaa actttttctg 780 tgatgaaggg tatcgactgc aaggcccacc ttctagtcgg tgtgtaattg ctggacaggg 840 agttgcttgg accaaaatgc cagtatgtga agaaattttt tgcccatcac ctccccctat 900 tctcaatgga agacatatag gcaactcact agcaaatgtc tcatatggaa gcatagtcac 960 ttacacttgt gacccggacc cagaggaagg agtgaacttc atccttattg gagagagcac 1020 tctccgttgt acagttgata gtcagaagac tgggacctgg agtggccctg ccccacgctg 1080 tgaactttct acttctgcgg ttcagtgtcc acatccccag atcctaagag gccgaatggt 1140 atctgggcag aaagatcgat atacctataa cgacactgtg atatttgctt gcatgtttgg 1200 cttcaccttg aagggcagca agcaaatccg atgcaatgcc caaggcacat gggagccatc 1260 tgcaccagtc tgtgaaaagg aatgccaggc ccctcctaac atcctcaatg ggcaaaagga 1320 agatagacac atggtccgct ttgaccctgg aacatctata aaatatagct gtaaccctgg 1380 ctatgtgctg gtgggagaag aatccataca gtgtacctct gaggtgtgga caccccctgt 1440 accccaatgc aaagtggcag cgtgtgaagc tacaggaagg caactcttga caaaacccca 1500 gcaccaattt gttagaccag atgtcaactc ttcttgtggt gaagggtaca agttaagtgg 1560 gagtgtttat caggagtgtc aaggcacaat tccttggttt atggagattc gtctttgtaa 1620 agaaatcacc tgcccaccac cccctgttat ctacaatggg gcacacaccg ggagttcctt 1680 agaagatttt ccatatggaa ccacggtcac ttacacatgt aaccctgggc cagaaagagg 1740 agtggaattc agcctcattg gagagagcac catccgttgt acaagcaatg atcaagaaag 1800 aggcacctgg agtggccctg ctcccctgtg taaactttcc ctccttgctg tccagtgctc 1860 acatgtccat attgcaaatg gatacaagat atctggcaag gaagccccat atttctacaa 1920 tgacactgtg acattcaagt gttatagtgg atttactttg aagggcagta gtcagattcg 1980 ttgcaaagct gataacacct gggatcctga aataccagtt tgtgaaaaag aaacatgcca 2040 gcatgtgaga cagagtcttc aagaacttcc agctggttca cgtgtggagc tagttaatac 2100 gtcctgccaa gatgggtacc agttgactgg acatgcttat cagatgtgtc aagatgctga 2160 aaatggaatt tggttcaaaa agattccact ttgtaaagtt attcactgtc accctccacc 2220 agtgattgtc aatgggaagc acacaggcat gatggcagaa aactttctat atggaaatga 2280 agtctcttat gaatgtgacc aaggattcta tctcctggga gagaaaaaat tgcagtgcag 2340 aagtgattct aaaggacatg gatcttggag cgggccttcc ccacagtgct tacgatctcc 2400 tcctgtgact cgctgcccta atccagaagt caaacatggg tacaagctca ataaaacaca 2460 ttctgcatat tcccacaatg acatagtgta tgttgactgc aatcctggct tcatcatgaa 2520 tggtagtcgc gtgattaggt gtcatactga taacacatgg gtgccaggtg tgccaacttg 2580 tatcaaaaaa gccttcatag ggtgtccacc tccgcctaag acccctaacg ggaaccatac 2640 tggtggaaac atagctcgat tttctcctgg aatgtcaatc ctgtacagct gtgaccaagg 2700 ctacctgctg gtgggagagg cactccttct ttgcacacat gagggaacct ggagccaacc 2760 tgcccctcat tgtaaagagg taaactgtag ctcaccagca gatatggatg gaatccagaa 2820 agggctggaa ccaaggaaaa tgtatcagta tggagctgtt gtaactctgg agtgtgaaga 2880 tgggtatatg ctggaaggca gtccccagag ccagtgccaa tcggatcacc aatggaaccc 2940 tcccctggcg gtttgcagat cccgttcact tgctcctgtc ctttgtggta ttgctgcagg 3000 tttgatactt cttaccttct tgattgtcgt taccttatac gtgatatcaa aacacagagc 3060 acgcaattat tatacagata caagccagaa agaagctttt catttagaag cacgagaagt 3120 atattctgtt gatccataca acccagccag ctgatcagaa gacaaactgg tgtgtgcctc 3180 attgcttgga attcagcgga atattgatta gaaagaaact gctctaatat cagcaagtct 3240 ctttatatgg cctcaagatc aatgaaatga tgtcataagc gatcacttcc tatatgcact 3300 tattctcaag aagaacatct ttatggtaaa gatgggagcc cagtttcact gccatatact 3360 cttcaaggac tttctgaagc ctcacttatg agatgcctga agccaggcca tggctataaa 3420 caattacatg gctctaaaaa gttttgccct ttttaaggaa ggcactaaaa agagctgtcc 3480 tggtatctag acccatcttc tttttgaaat cagcatactc aatgttacta tctgcttttg 3540 gttataatgt gtttttaatt atctaaagta tgaagcattt tctggggtta tgatggcctt 3600 acctttatta ggaagtatgg ttttattttg atagtagctt cctcctctgg ttggtgttaa 3660 tcatttcatt tttaccctta cttggtttga gtttctctac attactgtat atactttgcc 3720 tttccataat cactcagtga ttgcaatttg cacaagtttt tttaaattat gggaatcaag 3780 atttaatcct agagatttgg tgtacaattc aggctttgga tgtttcttta gcagttttgt 3840 gataagttct agttgcttgt aaaatttcac ttaataatgt gtacattagt cattcaataa 3900 attgtaattg taaagaaaac aaa 3923 <210> 292 <211> 1152 <212> DNA <213> HUMAN <400> 292 cgctcctcgg gctgcccctc ggttgacaat ggtctccagg atggtctcta ccatgctatc 60 tggcctactg ttttggctgg catctggatg gactccagca tttgcttaca gcccccggac 120 ccctgaccgg gtctcagaag cagatatcca gaggctgctt catggtgtta tggagcaatt 180 gggcattgcc aggccccgag tggaatatcc agctcaccag gccatgaatc ttgtgggccc 240 ccagagcatt gaaggtggag ctcatgaagg acttcagcat ttgggtcctt ttggcaacat 300 ccccaacatc gtggcagagt tgactggaga caacattcct aaggacttta gtgaggatca 360 ggggtaccca gaccctccaa atccctgtcc tgttggaaaa acagatgatg gatgtctaga 420 aaacacccct gacactgcag agttcagtcg agagttccag ttgcaccagc atctctttga 480 tccggaacat gactatccag gcttgggcaa gtggaacaag aaactccttt acgagaagat 540 gaagggagga gagagacgaa agcggaggag tgtcaatcca tatctacaag gacagagact 600 ggataatgtt gttgcaaaga agtctgtccc ccatttttca gatgaggata aggatccaga 660 gtaaagagaa gatgctagac gaaaacccac attacctgtt aggcctcagc atggcttatg 720 tgcacgtgta aatggagtcc ctgtgaatga cagcatgttt cttacataga taattatgga 780 tacaaagcag ctgtatgtag atagtgtatt gtcttcacac cgatgattct gctttttgct 840 aaattagaat aagagctttt ttgtttcttg ggtttttaaa atgtgaatct gcaatgatca 900 taaaaattaa aatgtgaatg tcaacaataa aaagcaagac tatgaaaggc tcagatttct 960 tgcagtttaa aatggtgtct gaggttgtac tattttggcc aagtctgtag aaagctgtca 1020 tttgattttg attatgtagt tcatccagcc cttgggcatt gttatacacc agtaaagaag 1080 gctgtactca agaggaggag ctgacacatt tcacttggct gcgtcttaat aaacatgaat 1140 gcaagcattg gc 1152 <210> 293 <211> 6951 <212> DNA <213> HUMAN <400> 293 cgtggtttgt agatgtgctt ggggagaatg ggggcctctt ctccaagaag cccggagcct 60 gtcgggccgc cggcgcccgg tctccccttc tgctgcggag gatccctgct ggcggttgtg 120 gtgctgcttg cgctgccggt ggcctggggt caatgcaatg ccccagaatg gcttccattt 180 gccaggccta ccaacctaac tgatgagttt gagtttccca ttgggacata tctgaactat 240 gaatgccgcc ctggttattc cggaagaccg ttttctatca tctgcctaaa aaactcagtc 300 tggactggtg ctaaggacag gtgcagacgt aaatcatgtc gtaatcctcc agatcctgtg 360 aatggcatgg tgcatgtgat caaaggcatc cagttcggat cccaaattaa atattcttgt 420 actaaaggat accgactcat tggttcctcg tctgccacat gcatcatctc aggtgatact 480 gtcatttggg ataatgaaac acctatttgt gacagaattc cttgtgggct accccccacc 540 atcaccaatg gagatttcat tagcaccaac agagagaatt ttcactatgg atcagtggtg 600 acctaccgct gcaatcctgg aagcggaggg agaaaggtgt ttgagcttgt gggtgagccc 660 tccatatact gcaccagcaa tgacgatcaa gtgggcatct ggagcggccc cgcccctcag 720 tgcattatac ctaacaaatg cacgcctcca aatgtggaaa atggaatatt ggtatctgac 780 aacagaagct tattttcctt aaatgaagtt gtggagttta ggtgtcagcc tggctttgtc 840 atgaaaggac cccgccgtgt gaagtgccag gccctgaaca aatgggagcc ggagctacca 900 agctgctcca gggtatgtca gccacctcca gatgtcctgc atgctgagcg tacccaaagg 960 gacaaggaca acttttcacc tgggcaggaa gtgttctaca gctgtgagcc cggctacgac 1020 ctcagagggg ctgcgtctat gcgctgcaca ccccagggag actggagccc tgcagccccc 1080 acatgtgaag tgaaatcctg tgatgacttc atgggccaac ttcttaatgg ccgtgtgcta 1140 tttccagtaa atctccagct tggagcaaaa gtggattttg tttgtgatga aggatttcaa 1200 ttaaaaggca gctctgctag ttactgtgtc ttggctggaa tggaaagcct ttggaatagc 1260 agtgttccag tgtgtgaaca aatcttttgt ccaagtcctc cagttattcc taatgggaga 1320 cacacaggaa aacctctgga agtctttccc tttggaaaag cagtaaatta cacatgcgac 1380 ccccacccag acagagggac gagcttcgac ctcattggag agagcaccat ccgctgcaca 1440 agtgaccctc aagggaatgg ggtttggagc agccctgccc ctcgctgtgg aattctgggt 1500 cactgtcaag ccccagatca ttttctgttt gccaagttga aaacccaaac caatgcatct 1560 gactttccca ttgggacatc tttaaagtac gaatgccgtc ctgagtacta cgggaggcca 1620 ttctctatca catgtctaga taacctggtc tggtcaagtc ccaaagatgt ctgtaaacgt 1680 aaatcatgta aaactcctcc agatccagtg aatggcatgg tgcatgtgat cacagacatc 1740 caggttggat ccagaatcaa ctattcttgt actacagggc accgactcat tggtcactca 1800 tctgctgaat gtatcctctc gggcaatgct gcccattgga gcacgaagcc gccaatttgt 1860 caacgaattc cttgtgggct accccccacc atcgccaatg gagatttcat tagcaccaac 1920 agagagaatt ttcactatgg atcagtggtg acctaccgct gcaatcctgg aagcggaggg 1980 agaaaggtgt ttgagcttgt gggtgagccc tccatatact gcaccagcaa tgacgatcaa 2040 gtgggcatct ggagcggccc ggcccctcag tgcattatac ctaacaaatg cacgcctcca 2100 aatgtggaaa atggaatatt ggtatctgac aacagaagct tattttcctt aaatgaagtt 2160 gtggagttta ggtgtcagcc tggctttgtc atgaaaggac cccgccgtgt gaagtgccag 2220 gccctgaaca aatgggagcc ggagctacca agctgctcca gggtatgtca gccacctcca 2280 gatgtcctgc atgctgagcg tacccaaagg gacaaggaca acttttcacc cgggcaggaa 2340 gtgttctaca gctgtgagcc cggctatgac ctcagagggg ctgcgtctat gcgctgcaca 2400 ccccagggag actggagccc tgcagccccc acatgtgaag tgaaatcctg tgatgacttc 2460 atgggccaac ttcttaatgg ccgtgtgcta tttccagtaa atctccagct tggagcaaaa 2520 gtggattttg tttgtgatga aggatttcaa ttaaaaggca gctctgctag ttattgtgtc 2580 ttggctggaa tggaaagcct ttggaatagc agtgttccag tgtgtgaaca aatcttttgt 2640 ccaagtcctc cagttattcc taatgggaga cacacaggaa aacctctgga agtctttccc 2700 tttggaaaag cagtaaatta cacatgcgac ccccacccag acagagggac gagcttcgac 2760 ctcattggag agagcaccat ccgctgcaca agtgaccctc aagggaatgg ggtttggagc 2820 agccctgccc ctcgctgtgg aattctgggt cactgtcaag ccccagatca ttttctgttt 2880 gccaagttga aaacccaaac caatgcatct gactttccca ttgggacatc tttaaagtac 2940 gaatgccgtc ctgagtacta cgggaggcca ttctctatca catgtctaga taacctggtc 3000 tggtcaagtc ccaaagatgt ctgtaaacgt aaatcatgta aaactcctcc agatccagtg 3060 aatggcatgg tgcatgtgat cacagacatc caggttggat ccagaatcaa ctattcttgt 3120 actacagggc accgactcat tggtcactca tctgctgaat gtatcctctc aggcaatact 3180 gcccattgga gcacgaagcc gccaatttgt caacgaattc cttgtgggct acccccaacc 3240 atcgccaatg gagatttcat tagcaccaac agagagaatt ttcactatgg atcagtggtg 3300 acctaccgct gcaatcttgg aagcagaggg agaaaggtgt ttgagcttgt gggtgagccc 3360 tccatatact gcaccagcaa tgacgatcaa gtgggcatct ggagcggccc cgcccctcag 3420 tgcattatac ctaacaaatg cacgcctcca aatgtggaaa atggaatatt ggtatctgac 3480 aacagaagct tattttcctt aaatgaagtt gtggagttta ggtgtcagcc tggctttgtc 3540 atgaaaggac cccgccgtgt gaagtgccag gccctgaaca aatgggagcc agagttacca 3600 agctgctcca gggtgtgtca gccgcctcca gaaatcctgc atggtgagca taccccaagc 3660 catcaggaca acttttcacc tgggcaggaa gtgttctaca gctgtgagcc tggctatgac 3720 ctcagagggg ctgcgtctct gcactgcaca ccccagggag actggagccc tgaagccccg 3780 agatgtgcag tgaaatcctg tgatgacttc ttgggtcaac tccctcatgg ccgtgtgcta 3840 tttccactta atctccagct tggggcaaag gtgtcctttg tctgtgatga agggtttcgc 3900 ttaaagggca gttccgttag tcattgtgtc ttggttggaa tgagaagcct ttggaataac 3960 agtgttcctg tgtgtgaaca tatcttttgt ccaaatcctc cagctatcct taatgggaga 4020 cacacaggaa ctccctctgg agatattccc tatggaaaag aaatatctta cacatgtgac 4080 ccccacccag acagagggat gaccttcaac ctcattgggg agagcaccat ccgctgcaca 4140 agtgaccctc atgggaatgg ggtttggagc agccctgccc ctcgctgtga actttctgtt 4200 cgtgctggtc actgtaaaac cccagagcag tttccatttg ccagtcctac gatcccaatt 4260 aatgactttg agtttccagt cgggacatct ttgaattatg aatgccgtcc tgggtatttt 4320 gggaaaatgt tctctatctc ctgcctagaa aacttggtct ggtcaagtgt tgaagacaac 4380 tgtagacgaa aatcatgtgg acctccacca gaacccttca atggaatggt gcatataaac 4440 acagatacac agtttggatc aacagttaat tattcttgta atgaagggtt tcgactcatt 4500 ggttccccat ctactacttg tctcgtctca ggcaataatg tcacatggga taagaaggca 4560 cctatttgtg agatcatatc ttgtgagcca cctccaacca tatccaatgg agacttctac 4620 agcaacaata gaacatcttt tcacaatgga acggtggtaa cttaccagtg ccacactgga 4680 ccagatggag aacagctgtt tgagcttgtg ggagaacggt caatatattg caccagcaaa 4740 gatgatcaag ttggtgtttg gagcagccct ccccctcggt gtatttctac taataaatgc 4800 acagctccag aagttgaaaa tgcaattaga gtaccaggaa acaggagttt cttttccctc 4860 actgagatca tcagatttag atgtcagccc gggtttgtca tggtagggtc ccacactgtg 4920 cagtgccaga ccaatggcag atgggggccc aagctgccac actgctccag ggtgtgtcag 4980 ccgcctccag aaatcctgca tggtgagcat accctaagcc atcaggacaa cttttcacct 5040 gggcaggaag tgttctacag ctgtgagccc agctatgacc tcagaggggc tgcgtctctg 5100 cactgcacgc cccagggaga ctggagccct gaagccccta gatgtacagt gaaatcctgt 5160 gatgacttcc tgggccaact ccctcatggc cgtgtgctac ttccacttaa tctccagctt 5220 ggggcaaagg tgtcctttgt ttgcgatgaa gggttccgat taaaaggcag gtctgctagt 5280 cattgtgtct tggctggaat gaaagccctt tggaatagca gtgttccagt gtgtgaacaa 5340 atcttttgtc caaatcctcc agctatcctt aatgggagac acacaggaac tccctttgga 5400 gatattccct atggaaaaga aatatcttac gcatgcgaca cccacccaga cagagggatg 5460 accttcaacc tcattgggga gagctccatc cgctgcacaa gtgaccctca agggaatggg 5520 gtttggagca gccctgcccc tcgctgtgaa ctttctgttc ctgctgcctg cccacatcca 5580 cccaagatcc aaaacgggca ttacattgga ggacacgtat ctctatatct tcctgggatg 5640 acaatcagct acacttgtga ccccggctac ctgttagtgg gaaagggctt cattttctgt 5700 acagaccagg gaatctggag ccaattggat cattattgca aagaagtaaa ttgtagcttc 5760 ccactgttta tgaatggaat ctcgaaggag ttagaaatga aaaaagtata tcactatgga 5820 gattatgtga ctttgaagtg tgaagatggg tatactctgg aaggcagtcc ctggagccag 5880 tgccaggcgg atgacagatg ggaccctcct ctggccaaat gtacctctcg tgcacatgat 5940 gctctcatag ttggcacttt atctggtacg atcttcttta ttttactcat cattttcctc 6000 tcttggataa ttctaaagca cagaaaaggc aataatgcac atgaaaaccc taaagaagtg 6060 gctatccatt tacattctca aggaggcagc agcgttcatc cccgaactct gcaaacaaat 6120 gaagaaaata gcagggtcct tccttgacaa agtactatac agctgaagaa catctcgaat 6180 acaattttgg tgggaaagga gccaattgat ttcaacagaa tcagatctga gcttcataaa 6240 gtctttgaag tgacttcaca gagacgcaga catgtgcact tgaagatgct gccccttccc 6300 tggtacctag caaagctcct gcctctttgt gtgcgtcact gtgaaacccc cacccttctg 6360 cctcgtgcta aacgcacaca gtatctagtc aggggaaaag actgcattta ggagatagaa 6420 aatagtttgg attacttaaa ggaataaggt gttgcctgga atttctggtt tgtaaggtgg 6480 tcactgttct tttttaaaat atttgtaata tggaatgggc tcagtaagaa gagcttggaa 6540 aatgcagaaa gttatgaaaa ataagtcact tataattatg ctacctactg ataaccactc 6600 ctaatatttt gattcatttt ctgcctatct tctttcacat atgtgttttt ttacatacgt 6660 acttttcccc ccttagtttg tttcctttta ttttatagag cagaacccta gtcttttaaa 6720 cagtttagag tgaaatatat gctatatcag tttttacttt ctctagggag aaaaattaat 6780 ttactagaaa ggcatgaaat gatcatggga agagtggtta agactactga agagaaatat 6840 ttggaaaata agatttcgat atcttctttt tttttgagat ggagtctggc tctgtctccc 6900 aggctggagt gcagtggcgt aatctcggct cactgcaacg tccgcctccc g 6951 <210> 294 <211> 4596 <212> DNA <213> HUMAN <400> 294 aagcggggga ctgtgccgtg tggaacgtgt agctgttgag aggtggactc tgttaccatt 60 gaggatgttt ggaggatgag tatgtgtggc agaggcacac ataaacaggc agagaccctt 120 tgcccctgcc tttctccccc aacccaaggc tgacctgtgt tctcccaggt ctgggattct 180 aagtgacctg ctctgtgttt ggtctctctc aggatgagca caagcctggg agatggcagt 240 gatggaaatg gcctgcccag gtgcccctgg ctcagcagtg gggcagcaga aggaactccc 300 caagccaaag gagaagacgc cgccactggg gaagaaacag agctccgtct acaagcttga 360 ggccgtggag aagagccctg tgttctgcgg aaagtgggag atcctgaatg acgtgattac 420 caagggcaca gccaaggaag gctccgaggc agggccagct gccatctcta tcatcgccca 480 ggctgagtgt gagaatagcc aagagttcag ccccaccttt tcagaacgca ttttcatcgc 540 tgggtccaaa cagtacagcc agtccgagag tcttgatcag atccccaaca atgtggccca 600 tgctacagag ggcaaaatgg cccgtgtgtg ttggaaggga aagcgtcgca gcaaagcccg 660 gaagaaacgg aagaagaaga gctcaaagtc cctggctcat gcaggagtgg ccttggccaa 720 acccctcccc aggacccctg agcaggagag ctgcaccatc ccagtgcagg aggatgagtc 780 tccactcggc gccccatatg ttagaaacac cccgcagttc accaagcctc tgaaggaacc 840 aggccttggg caactctgtt ttaagcagct tggcgagggc ctacggccgg ctctgcctcg 900 atcagaactc cacaaactga tcagcccctt gcaatgtctg aaccacgtgt ggaaactgca 960 ccacccccag gacggaggcc ccctgcccct gcccacgcac cccttcccct atagcagact 1020 gcctcatccc ttcccattcc accctctcca gccctggaaa cctcaccctc tggagtcctt 1080 cctgggcaaa ctggcctgtg tagacagcca gaaacccttg cctgacccac acctgagcaa 1140 actggcctgt gtagacagtc caaagcccct gcctggccca cacctggagc ccagctgcct 1200 gtctcgtggt gcccatgaga agttttctgt ggaggaatac ctagtgcatg ctctgcaagg 1260 cagcgtgagc tcaagccagg cccacagcct gaccagcctg gccaagacct gggcagcacg 1320 gggctccaga tcccgggagc ccagccccaa aactgaggac aacgagggtg tcctgctcac 1380 tgagaaactc aagccagtgg attatgagta ccgagaagaa gtccactggg ccacgcacca 1440 gctccgcctg ggcagaggct ccttcggaga ggtgcacagg atggaggaca agcagactgg 1500 cttccagtgc gctgtcaaaa aggtgcggct ggaagtattt cgggcagagg agctgatggc 1560 atgtgcagga ttgacctcac ccagaattgt ccctttgtat ggagctgtga gagaagggcc 1620 ttgggtcaac atcttcatgg agctgctgga aggtggctcc ctgggccagc tggtcaagga 1680 gcagggctgt ctcccagagg accgggccct gtactacctg ggccaggccc tggagggtct 1740 ggaatacctc cactcacgaa ggattctgca tggggacgtc aaagctgaca acgtgctcct 1800 gtccagcgat gggagccacg cagccctctg tgactttggc catgctgtgt gtcttcaacc 1860 tgatggcctg ggaaagtcct tgctcacagg ggactacatc cctggcacag agacccacat 1920 ggctccggag gtggtgctgg gcaggagctg cgacgccaag gtggatgtct ggagcagctg 1980 ctgtatgatg ctgcacatgc tcaacggctg ccacccctgg actcagttct tccgagggcc 2040 gctctgcctc aagattgcca gcgagcctcc gcctgtgagg gagatcccac cctcctgcgc 2100 ccctctcaca gcccaggcca tccaagaggg gctgaggaaa gagcccatcc accgcgtgtc 2160 tgcagcggag ctgggaggga aggtgaaccg ggcactacag caagtgggag gtctgaagag 2220 cccttggagg ggagaatata aagaaccaag acatccaccg ccaaatcaag ccaattacca 2280 ccagaccctc catgcccagc cgagagagct ttcgccaagg gccccagggc cccggccagc 2340 tgaggagaca acaggcagag cccctaagct ccagcctcct ctcccaccag agcccccaga 2400 gccaaacaag tctcctccct tgactttgag caaggaggag tctgggatgt gggaaccctt 2460 acctctgtcc tccctggagc cagcccctgc cagaaacccc agctcaccag agcggaaagc 2520 aaccgtcccg gagcaggaac tgcagcagct ggaaatagaa ttattcctca acagcctgtc 2580 ccagccattt tctctggagg agcaggagca aattctctcg tgcctcagca tcgacagcct 2640 ctccctgtcg gatgacagtg agaagaaccc atcaaaggcc tctcaaagct cgcgggacac 2700 cctgagctca ggcgtacact cctggagcag ccaggccgag gctcgaagct ccagctggaa 2760 catggtgctg gcccgggggc ggcccaccga caccccaagc tatttcaatg gtgtgaaagt 2820 ccaaatacag tctcttaatg gtgaacacct gcacatccgg gagttccacc gggtcaaagt 2880 gggagacatc gccactggca tcagcagcca gatcccagct gcagccttca gcttggtcac 2940 caaagacggg cagcctgttc gctacgacat ggaggtgcca gactcgggca tcgacctgca 3000 gtgcacactg gcccctgatg gcagcttcgc ctggagctgg agggtcaagc atggccagct 3060 ggagaacagg ccctaaccct gccctccacc gccggctcca cactgccgga aagcagcctt 3120 cctgctcggt gcacgatgct gccctgaaaa cacaggctca gccgttccca ggggattgcc 3180 agccccccgg ctcacagtgg gaaccagggc ctcgcagcag caaggtgggg gcaagcagaa 3240 tgcctcccag gatttcacac ctgagccctg ccccaccctg ctgaaaaaac atccgccacg 3300 tgaagagaca gaaggaggat ggcaggagtt acctggggaa acaaaacagg gatctttttc 3360 tgcccctgct ccagtcgagt tggcctgacc cgcttggatc agtgaccatt tgttggcaga 3420 caggggagag cagcttccag cctgggtcag aaggggtggg cgagcccttc ggcccctcac 3480 cctccaggct gctgtgagag tgtcaagtgt gtaagggccc aaactcaggt tcagtgcaga 3540 accaggtcag caggtatgcc cgcccgtagg ttaagggggc cctctaaacc ccttgcctgg 3600 cctcacctgg ccagctcacc ccttttgggt gtaggggaaa agaatgcctg accctgggaa 3660 ggctccctgg tagaatacac cacacttttc aggttgttgc aacacaggtc ctgagttgac 3720 ctctggttca gccaaggacc aaagaaggtg tgtaagtgaa gtggttctca gtccccagac 3780 atgtgcccct ttgctgctgg ctaccactct tccccagagc agcaggcccc gagccccttc 3840 aggcccagca ctgccccaga ctcgctggca ctcagttccc tcatctgtaa aggtgaaggg 3900 tgatgcagga tatgcctgac aggaacagtc tgtggatgga catgatcagt gctaaggaaa 3960 gcagcagaga gagacgtccg gcgccccagc cccactatca gtgtccagcg tgctggttcc 4020 ccagagcaca gctcagcatc acactgacac tcaccctgcc ctgcccctgg ccagagggta 4080 ctgccgacgg cactttgcac tctgatgacc tcaaagcact ttcatggctg ccctctggca 4140 gggcagggca gggcagtgac actgtaggag catagcaagc caggagatgg ggtgaaggga 4200 cacagtcttg agctgtccac atgcatgtga ctcctcaaac ctcttccaga tttctctaag 4260 aatagcaccc ccttccccat tgccccagct tagcctcttc tcccagggga gctactcagg 4320 actcacgtag cattaaatca gctgtgaatc gtcagggggt gtctgctagc ctcaacctcc 4380 tggggcaggg gacgccgaga ctccgtggga gaagctcatt cccacatctt gccaagacag 4440 cctttgtcca gctgtccaca ttgagtcaga ctgctcccgg ggagagagcc ccggccccca 4500 gcacataaag aactgcagcc ttggtactgc agagtctggg ttgtagagaa ctctttgtaa 4560 gcaataaagt ttggggtgat gacaaatgtt aaaaaa 4596 <210> 295 <211> 3424 <212> DNA <213> HUMAN <400> 295 aggatcagaa caatgcctcc aagaccatca tcaggtgaac tgtggggcat ccacttgatg 60 cccccaagaa tcctagtgga atgtttacta ccaaatggaa tgatagtgac tttagaatgc 120 ctccgtgagg ctacattagt aactataaag catgaactat ttaaagaagc aagaaaatac 180 cctctccatc aacttcttca agatgaatct tcttacattt tcgtaagtgt tacccaagaa 240 gcagaaaggg aagaattttt tgatgaaaca agacgacttt gtgatcttcg gctttttcaa 300 ccatttttaa aagtaattga accagtaggc aaccgtgaag aaaagatcct caatcgagaa 360 attggttttg ctatcggcat gccagtgtgc gaatttgata tggttaaaga tcctgaagta 420 caggacttcc gaagaaatat tcttaatgtt tgtaaagaag ctgtggatct tagggatctt 480 aattcacctc atagtagagc aatgtatgtc tatccgccac atgtagaatc ttcaccagag 540 ctgccaaagc acatatataa taaattggat agaggccaaa taatagtggt gatttgggta 600 atagtttctc caaataatga caagcagaag tatactctga aaatcaacca tgactgtgtg 660 ccagaacaag taattgctga agcaatcagg aaaaaaacta gaagtatgtt gctatcatct 720 gaacaattaa aactctgtgt tttagaatat cagggcaagt acattttaaa agtgtgtgga 780 tgtgatgaat acttcctaga aaaatatcct ctgagtcagt ataagtatat aagaagctgt 840 ataatgcttg ggaggatgcc caatttgaag atgatggcta aagaaagcct ttattctcaa 900 ctgccaatgg actgttttac aatgccatct tattccagac gcatttccac agctacacca 960 tatatgaatg gagaaacatc tacaaaatcc ctttgggtta taaatagagc actcagaata 1020 aaaattcttt gtgcaaccta cgtgaatcta aatattcgag acattgacaa gatttatgtt 1080 cgaacaggta tctaccatgg aggagaaccc ttatgtgaca atgtgaacac tcaaagagta 1140 ccttgttcca atcccaggtg gaatgaatgg ctgaattatg atatatacat tcctgatctt 1200 cctcgtgctg ctcgactttg cctttccatt tgctctgtta aaggccgaaa gggtgctaaa 1260 gaggaacact gtccattggc atggggaaat ataaacttgt ttgattacac agacactcta 1320 gtatctggaa aaatggcttt gaatctttgg ccagtacctc atggattaga agatttgctg 1380 aaccctattg gtgttactgg atcaaatcca aataaagaaa ctccatgctt agagttggag 1440 tttgactggt tcagcagtgt ggtaaagttc ccagatatgt cagtgattga agagcatgcc 1500 aattggtctg tatcccgaga agcaggattt agctattccc acgcaggact gagtaacaga 1560 ctagctagag acaatgaatt aagggaaaat gacaaagaac agctcaaagc aatttctaca 1620 cgagatcctc tctctgaaat cactgagcag gagaaagatt ttctatggag tcacagacac 1680 tattgtgtaa ctatccccga aattctaccc aaattgcttc tgtctgttaa atggaattct 1740 agagatgaag tagcccagat gtattgcttg gtaaaagatt ggcctccaat caaacctgaa 1800 caggctatgg aacttctgga ctgtaattac ccagatccta tggttcgagg ttttgctgtt 1860 cggtgcttgg aaaaatattt aacagatgac aaactttctc agtatttaat tcagctagta 1920 caggtcctaa aatatgaaca atatttggat aacttgcttg tgagattttt actgaagaaa 1980 gcattgacta atcaaaggat tgggcacttt ttcttttggc atttaaaatc tgagatgcac 2040 aataaaacag ttagccagag gtttggcctg cttttggagt cctattgtcg tgcatgtggg 2100 atgtatttga agcacctgaa taggcaagtc gaggcaatgg aaaagctcat taacttaact 2160 gacattctca aacaggagag gaaggatgaa acacaaaagg tacagatgaa gtttttagtt 2220 gagcaaatga ggcgaccaga tttcatggat gccctacagg gcttgctgtc tcctctaaac 2280 cctgctcatc aactaggaaa cctcaggctt aaagagtgtc gaattatgtc ttctgcaaaa 2340 aggccactgt ggttgaattg ggagaaccca gacatcatgt cagagttact gtttcagaac 2400 aatgagatca tctttaaaaa tggggatgat ttacggcaag atatgctaac acttcaaatt 2460 attcgtatta tggaaaatat ctggcaaaat caaggtcttg atcttcgaat gttaccttat 2520 ggttgtctgt caatcggtga ctgtgtggga cttattgagg tggtgcgaaa ttctcacact 2580 attatgcaaa ttcagtgcaa aggcggcttg aaaggtgcac tgcagttcaa cagccacaca 2640 ctacatcagt ggctcaaaga caagaacaaa ggagaaatat atgatgcagc cattgacctg 2700 tttacacgtt catgtgctgg atactgtgta gctaccttca ttttgggaat tggagatcgt 2760 cacaatagta acatcatggt gaaagacgat ggacaactgt ttcatataga ttttggacac 2820 tttttggatc acaagaagaa aaaatttggt tataaacgag aacgtgtgcc atttgttttg 2880 acacaggatt tcttaatagt gattagtaaa ggagcccaag aatgcacaaa gacaagagaa 2940 tttgagaggt ttcaggagat gtgttacaag gcttatctag ctattcgaca gcatgccaat 3000 ctcttcataa atcttttctc aatgatgctt ggctctggaa tgccagaact acaatctttt 3060 gatgacattg catacattcg aaagacccta gccttagata aaactgagca agaggctttg 3120 gagtatttca tgaaacaaat gaatgatgca catcatggtg gctggacaac aaaaatggat 3180 tggatcttcc acacaattaa acagcatgca ttgaactgaa agataactga gaaaatgaaa 3240 gctcactctg gattccacac tgcactgtta ataactctca gcaggcaaag accgattgca 3300 taggaattgc acaatccatg aacagcatta gatttacagc aagaacagaa ataaaatact 3360 atataattta aataatgtaa acgcaaacag ggtttgatag cacttaaact agttcatttc 3420 aaaa 3424 <210> 296 <211> 2484 <212> DNA <213> HUMAN <400> 296 gggcccggcg ctcgctgctc ccgcggcccg cgccatgccc tcctacacgg tcaccgtggc 60 cactggcagc cagtggttcg ccggcactga cgactacatc tacctcagcc tcgtgggctc 120 ggcgggctgc agcgagaagc acctgctgga caagcccttc tacaacgact tcgagcgtgg 180 cgcggtggat tcatacgacg tgactgtgga cgaggaactg ggcgagatcc agctggtcag 240 aatcgagaag cgcaagtact ggctgaatga cgactggtac ctgaagtaca tcacgctgaa 300 gacgccccac ggggactaca tcgagttccc ctgctaccgc tggatcaccg gcgatgtcga 360 ggttgtcctg agggatggac gcgcaaagtt ggcccgagat gaccaaattc acattctcaa 420 gcaacaccga cgtaaagaac tggaaacacg gcaaaaacaa tatcgatgga tggagtggaa 480 ccctggcttc cccttgagca tcgatgccaa atgccacaag gatttacccc gtgatatcca 540 gtttgatagt gaaaaaggag tggactttgt tctgaattac tccaaagcga tggagaacct 600 gttcatcaac cgcttcatgc acatgttcca gtcttcttgg aatgacttcg ccgactttga 660 gaaaatcttt gtcaagatca gcaacactat ttctgagcgg gtcatgaatc actggcagga 720 agacctgatg tttggctacc agttcctgaa tggctgcaac cctgtgttga tccggcgctg 780 cacagagctg cccgagaagc tcccggtgac cacggagatg gtagagtgca gcctggagcg 840 gcagctcagc ttggagcagg aggtccagca agggaacatt ttcatcgtgg actttgagct 900 gctggatggc atcgatgcca acaaaacaga cccctgcaca ctccagttcc tggccgctcc 960 catctgcttg ctgtataaga acctggccaa caagattgtc cccattgcca tccagctcaa 1020 ccaaatcccg ggagatgaga accctatttt cctcccttcg gatgcaaaat acgactggct 1080 tttggccaaa atctgggtgc gttccagtga cttccacgtc caccagacca tcacccacct 1140 tctgcgaaca catctggtgt ctgaggtttt tggcattgca atgtaccgcc agctgcctgc 1200 tgtgcacccc attttcaagc tgctggtggc acacgtgaga ttcaccattg caatcaacac 1260 caaggcccgt gagcagctca tctgcgagtg tggcctcttt gacaaggcca acgccacagg 1320 gggcggtggg cacgtgcaga tggtgcagag ggccatgaag gacctgacct atgcctccct 1380 gtgctttccc gaggccatca aggcccgggg catggagagc aaagaagaca tcccctacta 1440 cttctaccgg gacgacgggc tcctggtgtg ggaagccatc aggacgttca cggccgaggt 1500 ggtagacatc tactacgagg gcgaccaggt ggtggaggag gacccggagc tgcaggactt 1560 cgtgaacgat gtctacgtgt acggcatgcg gggccgcaag tcctcaggct tccccaagtc 1620 ggtcaagagc cgggagcagc tgtcggagta cctgaccgtg gtgatcttca ccgcctccgc 1680 ccagcacgcc gcggtcaact tcggccagta cgactggtgc tcctggatcc ccaatgcgcc 1740 cccaaccatg cgagccccgc caccgactgc caagggcgtg gtgaccattg agcagatcgt 1800 ggacacgctg cccgaccgcg gccgctcctg ctggcatctg ggtgcagtgt gggcgctgag 1860 ccagttccag gaaaacgagc tgttcctggg catgtaccca gaagagcatt ttatcgagaa 1920 gcctgtgaag gaagccatgg cccgattccg caagaacctc gaggccattg tcagcgtgat 1980 tgctgagcgc aacaagaaga agcagctgcc atattactac ttgtccccag accggattcc 2040 gaacagtgtg gccatctgag cacactgcca gtctcactgt gggaaggcca gctgccccag 2100 ccagatggac tccagcctgc ctggcaggtg tctggccagg cctcttggca gtcacatctc 2160 ttcctccgag gccagtacct ttccatttat tctttgatct tcagggaact gcatagattg 2220 atcaaagtgt aaacaccata gggacccatt ctacacagag caggactgca cagcgtcctg 2280 tccacaccca gctcagcatt tccacaccaa gcagcaacag caaatcacga ccactgatag 2340 atgtctattc ttgttggaga catgggatga ttattttctg ttctatttgt gcttagtcca 2400 attccttgca catagtaggt acccaattca attactattg aatgaattaa gaattggttg 2460 ccataaaaat aaatcagttc attt 2484 <210> 297 <211> 797 <212> DNA <213> HUMAN <400> 297 agtctctgct cttcccagcc tctccggcgc gctccaaggg cttcccgtcg ggaccatgcg 60 cggcagtgag ctcccgctgg tcctgctggc gctggtcctc tgcctagcgc cccgggggcg 120 agcggtcccg ctgcctgcgg gcggagggac cgtgctgacc aagatgtacc cgcgcggcaa 180 ccactgggcg gtggggcact taatggggaa aaagagcaca ggggagtctt cttctgtttc 240 tgagagaggg agcctgaagc agcagctgag agagtacatc aggtgggaag aagctgcaag 300 gaatttgctg ggtctcatag aagcaaagga gaacagaaac caccagccac ctcaacccaa 360 ggccttgggc aatcagcagc cttcgtggga ttcagaggat agcagcaact tcaaagatgt 420 aggttcaaaa ggcaaagttg gtagactctc tgctccaggt tctcaacgtg aaggaaggaa 480 cccccagctg aaccagcaat gataatgatg gcctctctca aaagagaaaa acaaaacccc 540 taagagactg agttctgcaa gcatcagttc tacggatcat caacaagatt tccttgtgca 600 aaatatttga ctattctgta tctttcatcc ttgactaaat tcgtgatttt caagcagcat 660 cttctggttt aaacttgttt gctgtgaaca attgtcgaaa agagtcttcc aattaatgct 720 tttttatatc taggctacct gttggttaga ttcaaggccc cgagctgtta ccattcacaa 780 taaaagctta aacacat 797 <210> 298 <211> 5784 <212> DNA <213> HUMAN <400> 298 acggcatcca gtacagaggg gctggacttg gacccctgca gcagccctgc acaggagaag 60 cggcatataa agccgcgctg cccgggagcc gctcggccac gtccaccgga gcatcctgca 120 ctgcagggcc ggtctctcgc tccagcagag cctgcgcctt tctgactcgg tccggaacac 180 tgaaaccagt catcactgca tctttttggc aaaccaggag ctcagctgca ggaggcagga 240 tggtctggag gctggtcctg ctggctctgt gggtgtggcc cagcacgcaa gctggtcacc 300 aggacaaaga cacgaccttc gaccttttca gtatcagcaa catcaaccgc aagaccattg 360 gcgccaagca gttccgcggg cccgaccccg gcgtgccggc ttaccgcttc gtgcgctttg 420 actacatccc accggtgaac gcagatgacc tcagcaagat caccaagatc atgcggcaga 480 aggagggctt cttcctcacg gcccagctca agcaggacgg caagtccagg ggcacgctgt 540 tggctctgga gggccccggt ctctcccaga ggcagttcga gatcgtctcc aacggccccg 600 cggacacgct ggatctcacc tactggattg acggcacccg gcatgtggtc tccctggagg 660 acgtcggcct ggctgactcg cagtggaaga acgtcaccgt gcaggtggct ggcgagacct 720 acagcttgca cgtgggctgc gacctcatag gaccagttgc tctggacgag cccttctacg 780 agcacctgca ggcggaaaag agccggatgt acgtggccaa aggctctgcc agagagagtc 840 acttcagggg tttgcttcag aacgtccacc tagtgtttga aaactctgtg gaagatattc 900 taagcaagaa gggttgccag caaggccagg gagctgagat caacgccatc agtgagaaca 960 cagagacgct gcgcctgggt ccgcatgtca ccaccgagta cgtgggcccc agctcggaga 1020 ggaggcccga ggtgtgcgaa cgctcgtgcg aggagctggg aaacatggtc caggagctct 1080 cggggctcca cgtcctcgtg aaccagctca gcgagaacct caagagagtg tcgaatgata 1140 accagtttct ctgggagctc attggtggcc ctcctaagac aaggaacatg tcagcttgct 1200 ggcaggatgg ccggttcttt gcggaaaatg aaacgtgggt ggtggacagc tgcaccacgt 1260 gtacctgcaa gaaatttaaa accatttgcc accaaatcac ctgcccgcct gcaacctgcg 1320 ccagtccatc ctttgtggaa ggcgaatgct gcccttcctg cctccactcg gtggacggtg 1380 aggagggctg gtctccgtgg gcagagtgga cccagtgctc cgtgacgtgt ggctctggga 1440 cccagcagag aggccggtcc tgtgacgtca ccagcaacac ctgcttgggg ccctcgatcc 1500 agacacgggc ttgcagtctg agcaagtgtg acacccgcat ccggcaggac ggcggctgga 1560 gccactggtc accttggtct tcatgctctg tgacctgtgg agttggcaat atcacacgca 1620 tccgtctctg caactcccca gtgccccaga tggggggcaa gaattgcaaa gggagtggcc 1680 gggagaccaa agcctgccag ggcgccccat gcccaatcga tggccgctgg agcccctggt 1740 ccccgtggtc ggcctgcact gtcacctgtg ccggtgggat ccgggagcgc acccgggtct 1800 gcaacagccc tgagcctcag tacggaggga aggcctgcgt gggggatgtg caggagcgtc 1860 agatgtgcaa caagaggagc tgccccgtgg atggctgttt atccaacccc tgcttcccgg 1920 gagcccagtg cagcagcttc cccgatgggt cctggtcatg cggcttctgc cctgtgggct 1980 tcttgggcaa tggcacccac tgtgaggacc tggacgagtg tgccctggtc cccgacatct 2040 gcttctccac cagcaaggtg cctcgctgtg tcaacactca gcctggcttc cactgcctgc 2100 cctgcccgcc ccgatacaga gggaaccagc ccgtcggggt cggcctggaa gcagccaaga 2160 cggaaaagca agtgtgtgag cccgaaaacc catgcaagga caagacacac aactgccaca 2220 agcacgcgga gtgcatctac ctgggtcact tcagcgaccc catgtacaag tgcgagtgcc 2280 agacaggcta cgcgggcgac gggctcatct gcggggagga ctcggacctg gacggctggc 2340 ccaacctcaa tctggtctgc gccaccaacg ccacctacca ctgcatcaag gataactgcc 2400 cccatctgcc aaattctggg caggaagact ttgacaagga cgggattggc gatgcctgtg 2460 atgatgacga tgacaatgac ggtgtgaccg atgagaagga caactgccag ctcctcttca 2520 atccccgcca ggctgactat gacaaggatg aggttgggga ccgctgtgac aactgccctt 2580 acgtgcacaa ccctgcccag atcgacacag acaacaatgg agagggtgac gcctgctccg 2640 tggacattga tggggacgat gtcttcaatg aacgagacaa ttgtccctac gtctacaaca 2700 ctgaccagag ggacacggat ggtgacggtg tgggggatca ctgtgacaac tgccccctgg 2760 tgcacaaccc tgaccagacc gacgtggaca atgaccttgt tggggaccag tgtgacaaca 2820 acgaggacat agatgacgac ggccaccaga acaaccagga caactgcccc tacatctcca 2880 acgccaacca ggctgaccat gacagagacg gccagggcga cgcctgtgac cctgatgatg 2940 acaacgatgg cgtccccgat gacagggaca actgccggct tgtgttcaac ccagaccagg 3000 aggacttgga cggtgatgga cggggtgata tttgtaaaga tgattttgac aatgacaaca 3060 tcccagatat tgatgatgtg tgtcctgaaa acaatgccat cagtgagaca gacttcagga 3120 acttccagat ggtccccttg gatcccaaag ggaccaccca aattgatccc aactgggtca 3180 ttcgccatca aggcaaggag ctggttcaga cagccaactc ggaccccggc atcgctgtag 3240 gttttgacga gtttgggtct gtggacttca gtggcacatt ctacgtaaac actgaccggg 3300 acgacgacta tgctggcttc gtctttggtt accagtcaag cagccgcttc tatgtggtga 3360 tgtggaagca ggtgacgcag acctactggg aggaccagcc cacgcgggcc tatggctact 3420 ccggcgtgtc cctcaaggtg gtgaactcca ccacggggac gggcgagcac ctgaggaacg 3480 cgctgtggca cacggggaac acgccggggc aggtgcgaac cttatggcac gaccccagga 3540 acattggctg gaaggactac acggcctata ggtggcacct gactcacagg cccaagaccg 3600 gctacatcag agtcttagtg catgaaggaa aacaggtcat ggcagactca ggacctatct 3660 atgaccaaac ctacgctggc gggcggctgg gtctatttgt cttctctcaa gaaatggtct 3720 atttctcaga cctcaagtac gaatgcagag atatttaaac aagatttgct gcatttccgg 3780 caatgccctg tgcatgccat ggtccctaga cacctcagtt cattgtggtc cttgcggctt 3840 ctctctctag cagcacctcc tgtcccttga ccttaactct gatggttctt cacctcctgc 3900 cagcaacccc aaacccaagt gccttcagag gataaatatc aatggaactc agagatgaac 3960 atctaaccca ctagaggaaa ccagtttggt gatatatgag actttatgtg gagtgaaaat 4020 tgggcatgcc attacattgc tttttcttgt ttgtttaaaa agaatgacgt ttacatataa 4080 aatgtaatta cttattgtat ttatgtgtat atggagttga agggaatact gtgcataagc 4140 cattatgata aattaagcat gaaaaatatt gctgaactac ttttggtgct taaagttgtc 4200 actattcttg aattagagtt gctctacaat gacacacaaa tcccgctaaa taaattataa 4260 acaagggtca attcaaattt gaagtaatgt tttagtaagg agagattaga agacaacagg 4320 catagcaaat gacataagct accgattaac taatcggaac atgtaaaaca gttacaaaaa 4380 taaacgaact ctcctcttgt cctacaatga aagccctcat gtgcagtaga gatgcagttt 4440 catcaaagaa caaacatcct tgcaaatggg tgtgacgcgg ttccagatgt ggatttggca 4500 aaacctcatt taagtaaaag gttagcagag caaagtgcgg tgctttagct gctgcttgtg 4560 ccgttgtggc gtcggggagg ctcctgcctg agcttccttc cccagctttg ctgcctgaga 4620 ggaaccagag cagacgcaca ggccggaaaa ggcgcatcta acgcgtatct aggctttggt 4680 aactgcggac aagttgcttt tacctgattt gatgatacat ttcattaagg ttccagttat 4740 aaatattttg ttaatattta ttaagtgact atagaatgca actccattta ccagtaactt 4800 attttaaata tgcctagtaa cacatatgta gtataatttc tagaaacaaa catctaataa 4860 gtatataatc ctgtgaaaat atgaggcttg ataatattag gttgtcacga tgaagcatgc 4920 tagaagctgt aacagaatac atagagaata atgaggagtt tatgatggaa ccttaatata 4980 taatgttgcc agcgatttta gttcaatatt tgttactgtt atctatctgc tgtatatgga 5040 attcttttaa ttcaaacgct gaaaacgaat cagcatttag tcttgccagg cacacccaat 5100 aatcagtcat gtgtaatatg cacaagtttg tttttgtttt tgtttttttt gttggttggt 5160 ttttttgctt taagttgcat gatctttctg caggaaatag tcactcatcc cactccacat 5220 aaggggttta gtaagagaag tctgtctgtc tgatgatgga tagggggcaa atctttttcc 5280 cctttctgtt aatagtcatc acatttctat gccaaacagg aacgatccat aactttagtc 5340 ttaatgtaca cattgcattt tgataaaatt aattttgttg tttcctttga ggttgatcgt 5400 tgtgttgttt tgctgcactt tttacttttt tgcgtgtgga gctgtattcc cgagacaacg 5460 aagcgttggg atacttcatt aaatgtagcg actgtcaaca gcgtgcaggt tttctgtttc 5520 tgtgttgtgg ggtcaaccgt acaatggtgt gggaatgacg atgatgtgaa tatttagaat 5580 gtaccatatt ttttgtaaat tatttatgtt tttctaaaca aatttatcgt ataggttgat 5640 gaaacgtcat gtgttttgcc aaagactgta aatatttatt tatgtgttca catggtcaaa 5700 atttcaccac tgaaaccctg cacttagcta gaacctcatt tttaaagatt aacaacagga 5760 aataaattgt aaaaaaggtt ttct 5784 <210> 299 <211> 800 <212> DNA <213> HUMAN <400> 299 accaccatga atccactcct gatccttacc tttgtggcag ctgctcttgc tgcccccttt 60 gatgatgatg acaagatcgt tgggggctac aactgtgagg agaattctgt cccctaccag 120 gtgtccctga attctggcta ccacttctgt ggtggctccc tcatcaacga acagtgggtg 180 gtatcagcag gccactgcta caagtcccgc atccaggtga gactgggaga gcacaacatc 240 gaagtcctgg aggggaatga gcagttcatc aatgcagcca agatcatccg ccacccccaa 300 tacgacagga agactctgaa caatgacatc atgttaatca agctctcctc acgtgcagta 360 atcaacgccc gcgtgtccac catctctctg cccaccgccc ctccagccac tggcacgaag 420 tgcctcatct ctggctgggg caacactgcg agctctggcg ccgactaccc agacgagctg 480 cagtgcctgg atgctcctgt gctgagccag gctaagtgtg aagcctccta ccctggaaag 540 attaccagca acatgttctg tgtgggcttc cttgagggag gcaaggattc atgtcagggt 600 gattctggtg gccctgtggt ctgcaatgga cagctccaag gagttgtctc ctggggtgat 660 ggctgtgccc agaagaacaa gcctggagtc tacaccaagg tctacaacta cgtgaaatgg 720 attaagaaca ccatagctgc caatagctaa agcccccagt atctcttcag tctctatacc 780 aataaagtga ccctgttctc 800 <210> 300 <211> 1113 <212> DNA <213> HUMAN <400> 300 gaattccggg aacgaaagag aagctctatc tcccctccag gagcccagct atgaactcct 60 tctccacaag cgccttcggt ccagttgcct tctccctggg gctgctcctg gtgttgcctg 120 ctgccttccc tgccccagta cccccaggag aagattccaa agatgtagcc gccccacaca 180 gacagccact cacctcttca gaacgaattg acaaacaaat tcggtacatc ctcgacggca 240 tctcagccct gagaaaggag acatgtaaca agagtaacat gtgtgaaagc agcaaagagg 300 cactggcaga aaacaacctg aaccttccaa agatggctga aaaagatgga tgcttccaat 360 ctggattcaa tgaggagact tgcctggtga aaatcatcac tggtcttttg gagtttgagg 420 tatacctaga gtacctccag aacagatttg agagtagtga ggaacaagcc agagctgtgc 480 agatgagtac aaaagtcctg atccagttcc tgcagaaaaa ggcaaagaat ctagatgcaa 540 taaccacccc tgacccaacc acaaatgcca gcctgctgac gaagctgcag gcacagaacc 600 agtggctgca ggacatgaca actcatctca ttctgcgcag ctttaaggag ttcctgcagt 660 ccagcctgag ggctcttcgg caaatgtagc atgggcacct cagattgttg ttgttaatgg 720 gcattccttc ttctggtcag aaacctgtcc actgggcaca gaacttatgt tgttctctat 780 ggagaactaa aagtatgagc gttaggacac tattttaatt atttttaatt tattaatatt 840 taaatatgtg aagctgagtt aatttatgta agtcatattt atatttttaa gaagtaccac 900 ttgaaacatt ttatgtatta gttttgaaat aataatggaa agtggctatg cagtttgaat 960 atcctttgtt tcagagccag atcatttctt ggaaagtgta ggcttacctc aaataaatgg 1020 ctaacttata catattttta aagaaatatt tatattgtat ttatataatg tataaatggt 1080 ttttatacca ataaatggca ttttaaaaaa ttc 1113 <210> 301 <211> 2360 <212> DNA <213> HUMAN <400> 301 gctacgcggg ccacgctgct ggctggcctg acctaggcgc gcggggtcgg gcggccgcgc 60 gggcgggctg agtgagcaag acaagacact caagaagagc gagctgcgcc tgggtcccgg 120 ccaggcttgc acgcagaggc gggcggcaga cggtgcccgg cggaatctcc tgagctccgc 180 cgcccagctc tggtgccagc gcccagtggc cgccgcttcg aaagtgactg gtgcctcgcc 240 gcctcctctc ggtgcgggac catgaagctg ctgccgtcgg tggtgctgaa gctctttctg 300 gctgcagttc tctcggcact ggtgactggc gagagcctgg agcggcttcg gagagggcta 360 gctgctggaa ccagcaaccc ggaccctccc actgtatcca cggaccagct gctaccccta 420 ggaggcggcc gggaccggaa agtccgtgac ttgcaagagg cagatctgga ccttttgaga 480 gtcactttat cctccaagcc acaagcactg gccacaccaa acaaggagga gcacgggaaa 540 agaaagaaga aaggcaaggg gctagggaag aagagggacc catgtcttcg gaaatacaag 600 gacttctgca tccatggaga atgcaaatat gtgaaggagc tccgggctcc ctcctgcatc 660 tgccacccgg gttaccatgg agagaggtgt catgggctga gcctcccagt ggaaaatcgc 720 ttatatacct atgaccacac aaccatcctg gccgtggtgg ctgtggtgct gtcatctgtc 780 tgtctgctgg tcatcgtggg gcttctcatg tttaggtacc ataggagagg aggttatgat 840 gtggaaaatg aagagaaagt gaagttgggc atgactaatt cccactgaga gagacttgtg 900 ctcaaggaat cggctgggga ctgctacctc tgagaagaca caaggtgatt tcagactgca 960 gaggggaaag acttccatct agtcacaaag actccttcgt ccccagttgc cgtctaggat 1020 tgggcctccc ataattgctt tgccaaaata ccagagcctt caagtgccaa acagagtatg 1080 tccgatggta tctgggtaag aagaaagcaa aagcaaggga ccttcatgcc cttctgattc 1140 ccctccacca aaccccactt cccctcataa gtttgtttaa acacttatct tctggattag 1200 aatgccggtt aaattccata tgctccagga tctttgactg aaaaaaaaaa agaagaagaa 1260 gaaggagagc aagaaggaaa gatttgtgaa ctggaagaaa gcaacaaaga ttgagaagcc 1320 atgtactcaa gtaccaccaa gggatctgcc attgggaccc tccagtgctg gatttgatga 1380 gttaactgtg aaataccaca agcctgagaa ctgaattttg ggacttctac ccagatggaa 1440 aaataacaac tatttttgtt gttgttgttt gtaaatgcct cttaaattat atatttattt 1500 tattctatgt atgttaattt atttagtttt taacaatcta acaataatat ttcaagtgcc 1560 tagactgtta ctttggcaat ttcctggccc tccactcctc atccccacaa tctggcttag 1620 tgccacccac ctttgccaca aagctaggat ggttctgtga cccatctgta gtaatttatt 1680 gtctgtctac atttctgcag atcttccgtg gtcagagtgc cactgcggga gctctgtatg 1740 gtcaggatgt aggggttaac ttggtcagag ccactctatg agttggactt cagtcttgcc 1800 taggcgattt tgtctaccat ttgtgttttg aaagcccaag gtgctgatgt caaagtgtaa 1860 cagatatcag tgtctccccg tgtcctctcc ctgccaagtc tcagaagagg ttgggcttcc 1920 atgcctgtag ctttcctggt ccctcacccc catggcccca ggccacagcg tgggaactca 1980 ctttcccttg tgtcaagaca tttctctaac tcctgccatt cttctggtgc tactccatgc 2040 aggggtcagt gcagcagagg acagtctgga gaaggtatta gcaaagcaaa aggctgagaa 2100 ggaacaggga acattggagc tgactgttct tggtaactga ttacctgcca attgctaccg 2160 agaaggttgg aggtggggaa ggctttgtat aatcccaccc acctcaccaa aacgatgaag 2220 gtatgctgtc atggtccttt ctggaagttt ctggtgccat ttctgaactg ttacaacttg 2280 tatttccaaa cctggttcat atttatactt tgcaatccaa ataaagataa cccttattcc 2340 ataaaaaaaa aaaaaaaaaa 2360 <210> 302 <211> 1642 <212> DNA <213> HUMAN <400> 302 ctctaaaggt tcgggggtgg aatccttggg ccgctgggca agcggcgaga cctggccagg 60 gccagcgagc cgaggacaga gggcgcacgg agggccgggc cgcagccccg gccgcttgca 120 gaccccgcca tggacccgtt cctggtgctg ctgcactcgg tgtcgtccag cctgtcgagc 180 agcgagctga ccgagctcaa gttcctatgc ctcgggcgcg tgggcaagcg caagctggag 240 cgcgtgcaga gcggcctaga cctcttctcc atgctgctgg agcagaacga cctggagccc 300 gggcacaccg agctcctgcg cgagctgctc gcctccctgc ggcgccacga cctgctgcgg 360 cgcgtcgacg acttcgaggc gggggcggcg gccggggccg cgcctgggga agaagacctg 420 tgtgcagcat ttaacgtcat atgtgataat gtggggaaag attggagaag gctggctcgt 480 cagctcaaag tctcagacac caagatcgac agcatcgagg acagataccc ccgcaacctg 540 acagagcgtg tgcgggagtc actgagaatc tggaagaaca cagagaagga gaacgcaaca 600 gtggcccacc tggtgggggc tctcaggtcc tgccagatga acctggtggc tgacctggta 660 caagaggttc agcaggcccg tgacctccag aacaggagtg gggccatgtc cccgatgtca 720 tggaactcag acgcatctac ctccgaagcg tcctgatggg ccgctgcttt gcgctggtgg 780 accacaggca tctacacagc ctggactttg gttctctcca ggaaggtagc ccagcactgt 840 gaagacccag caggaagcca ggctgagtga gccacagacc acctgcttct gaactcaagc 900 tgcgtttatt aatgcctctc ccgcaccagg ccgggcttgg gccctgcaca gatatttcca 960 tttcttcctc actatgacac tgagcaagat cttgtctcca ctaaatgagc tcctgcggga 1020 gtagttggaa agttggaacc gtgtccagca cagaaggaat ctgtgcagat gagcagtcac 1080 actgttactc cacagcggag gagaccagct cagaggccca ggaatcggag cgaagcagag 1140 aggtggagaa ctgggatttg aacccccgcc atccttcacc agagcccatg ctcaaccact 1200 gtggcgttct gctgcccctg cagttggcag aaaggatgtt ttgtcccatt tccttggagg 1260 ccaccgggac agacctggac actagggtca ggcggggtgc tgtggtgggg agaggcatgg 1320 ctggggtggg ggtggggaga cctggttggc cgtggtccag ctcttggccc ctgtgtgagt 1380 tgagtctcct ctctgagact gctaagtagg ggcagtgatg gttgccagga cgaattgaga 1440 taatatctgt gaggtgctga tgagtgattg acacacagca ctctctaaat cttccttgtg 1500 aggattatgg gtcctgcaat tctacagttt cttactgttt tgtatcaaaa tcactatctt 1560 tctgataaca gaattgccaa ggcagcggga tctcgtatct ttaaaaagca gtcctcttat 1620 tcctaaggta atcctattaa aa 1642 <210> 303 <211> 895 <212> DNA <213> HUMAN <400> 303 agagacttaa gtctaaggca ctgagcgtat catgttaaag atgagcgggt ggcagcgaca 60 gagccaaaat cagagctgga acctgaggag agagtgttca agaaggaagt gtatcttcat 120 acatcaccac acctgaaagc agatgtgctt ttccagactg atccaactgc agagatggca 180 gctgagtcat tgcctttctc ttcggacact gtcagctggg agctggaagc ctggtatgag 240 gacctgcaag aggtcctgtc ttcagatgaa aatgggggta cctatgtttc acctcctgga 300 aatgaagagg aagaatcaaa aatcttcacc actcttgacc ctgcttctct ggcttggctg 360 actgaggagg agccagaacc agcagaggtc acaagcacct cccagagccc tcactctcca 420 gattccagtc agagctccct ggctcaggag gaagaggagg aagaccaagg gagaaccagg 480 aaacggaaac agagtggtca ttccccagcc cgggctggaa agcagcgcat gaaggagaaa 540 gaacaggaga atgaaaggaa agtggcacag ctagctgaag agaatgaacg gctcaagcag 600 gaaatcgagc gcctgaccag ggaagtagag gcgactcgcc gagctctgat tgaccgaatg 660 gtgaatctgc accaagcatg aacaattggg agcatcagtc ccccacttgg gccacactac 720 ccacctttcc cagaagtggc tactgactac cctctcacta gtgccaatga tgtgaccctc 780 aatcccacat acgcaggggg aaggcttgga gtagacaaaa ggaaaggtct cagcttgtat 840 atagagattg tacatttatt tattactgtc cctatctatt aaagtgactt tctat 895 <210> 304 <211> 304 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(304) <223> N=any base <400> 304 gtgggcatct acantggnac ccacgtcatc cctaatgaca ggaagatcat ctggccaggc 60 ggagagacag agaagtctcg agggtaccag atgtccacca gactgaagat tgtgacgatc 120 caccaggagc ccttcgtgta cgtcaagccc acgctgagtg atgggacatg caaggaggag 180 ttcacagtca acggcgaccc agtcaagaag gtgatctgca ccgggcccaa cgacacgtcg 240 ccgggcagcc cccgccacac ggtgcctcag tgttgctacg gcttttgcat agacctgctc 300 atca 304 <210> 305 <211> 77 <212> DNA <213> HUMAN <400> 305 ctactcctag atatttggca tgatcttcag tatgatcttg tgctgtgcta tccgcaggaa 60 ccgcgagatg gtctaga 77 <210> 306 <211> 332 <212> DNA <213> HUMAN <400> 306 ttcacacgtg acccaggcct ctctccggtc tcacatggga gttgtgcccc aagacactgt 60 cctctttaat gacaccatcg ccgacaatat ccgttacggc cgtgtcacag ctgggaatga 120 tgaggtggag gctgctgctc aggctgcagg catccatgat gccattatgg ctttccctga 180 agggtacagg acacaggtgg gcgagcgggg actgaagctg agcggcgggg agaagcagcg 240 cgtcgccatt gcccgcacca tcctcaaggc tccgggcatc attctgctgg atgaggcaac 300 gtcagcgctg gatacatcta atgagagggc ca 332 <210> 307 <211> 371 <212> DNA <213> HUMAN <400> 307 ccaggattcc atgctactag tgctgactgc tgcatctcct acaccccacg aagcatcccg 60 tgttcactcc tggagagtta ctttgaaacg aacagcgagt gctccaagcc gggtgtcatc 120 ttcctcacca agaaggggcg acgtttctgt gccaacccca gtgataagca agttcaggtt 180 tgcatgagaa tgctgaagct ggacacacgg atcaagacca ggaagaattg aacttgtcaa 240 ggtgaaggga cacaagttgc cagccaccaa ctttcttgcc tcaactacct tcctgaatta 300 tttttttaag aagcatttat tcttgtgttc tggatttaga gcaattcatc taataaacag 360 tttctcactt a 371 <210> 308 <211> 508 <212> DNA <213> HUMAN <400> 308 gctcttcgtc tcagtcccag acacgagctg gaccacgcaa gtatcaaggg gctctgcaga 60 aggagctctg agagaaacag ctggctcaga gggtcctggc cccacgaggc cacctgtctg 120 tccacagcgg ccatcatgtt tgctgccaac ctgactctgg ggctgtacat ccactttggc 180 cccaggcctc tgagccccaa cagcactgcg ggcctggaaa gcgagtcctg gggggacttg 240 gcgcaccctg gcagcacccg ctggctacct caccctggtg cccctgctgg ccaccatgct 300 cttcatcatg ggctacgccg tgggctgggg tcccatcacc tggctgctca tgtctgaggt 360 cctgcccctg cgtgcccgtg gcgtggcctc agggctctgc gtgctggcca gctggctcac 420 cgccttcgtc ctcaccaagt ccttcctgcc agtggtgagc acttcggcct ccaggtgcct 480 ttcttcttct tcgcggcatt gttggtga 508 <210> 309 <211> 215 <212> DNA <213> HUMAN <400> 309 ctttcacaca aagaaaaagt tgtctgtgtg cgcaaatcca aaacagactt gggtgaaata 60 tattgtgcgt ctcctcagta aaaaagtcaa gaacatgtaa aaactgtggc ttttctggaa 120 tggaattgga catagcccaa gaacagaaag aaccttgctg gggttggagg tttcacttgc 180 acatcatgga gggtttagtg cttatctaat ttgtg 215 <210> 310 <211> 149 <212> DNA <213> HUMAN <400> 310 tggaataatt ttgagagtaa tttgaagaat tagatgcaaa taaatttgaa aacctttaaa 60 aagaaaccaa tggcctaact gacccaagaa gggaaagaaa atctaaacag actgataaat 120 acaaaatgaa attcagacac ttacagagc 149 <210> 311 <211> 252 <212> DNA <213> HUMAN <400> 311 ggaaaacgcc gtcctttgaa taacaattct gaaattgcac tgtcactaag cagaaataaa 60 gtttttgtct tttttgatct gactgtagat gatcagtcag tttatcctaa ggcattaaga 120 gatgaataca tcatgtcaaa aactcttgga agtggtgcct gtggagaggt aaagctggct 180 ttcgagagga aaacatgtaa gaaagtagcc ataaagatca tcagcaaaag gaagtttgct 240 attggttcag ca 252 <210> 312 <211> 554 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(554) <223> N=any base <400> 312 catatagcag acattccata aaataacatt ttccaaatta attatgcata catatacatc 60 tgctaattga atgacactgg tagatacatc ttcattaaga tgtgagtttt atgcttgtta 120 ctgcatattt tcaattatga attaagggca agaatcaccg tcttcctgtg aatacattcc 180 cataatttaa gaattccact aagctacatt ctgtctacca gtttgtaagc aaatgtctct 240 acagaccttt caagtattta tagttggtgc acagtaactc cacttatttt gtataatgtt 300 gctcaaccga atgtgggata ctataattat agcataatta ttcatagtta cagtaaaact 360 ctaaaccatt ttatttagaa tatttcagca gtgaacagaa cctacatgaa agtgtgccaa 420 aataatttgt gattgtttac tgaaatttat gagacttgta ataggctctg tctgaacaca 480 tatgaaaaat gtagatagtg atagtttctg tatatgggct ggcttacagc ttccctacat 540 tcatatttnt ctat 554 <210> 313 <211> 274 <212> DNA <213> HUMAN <400> 313 gtgatctcat atgattctcc aaacttttga gattaattat cttttataaa tgaggtaatg 60 agattttaaa gagtttagat gacttgccta actgacaaca ctgtcagtgg caaagttggg 120 atttgaactc agtctgatgg gcaaaaagag ttgtcttcta ccagccaagt tgccataaaa 180 gaaaactatg cattgtgcat agttttactc ttgttaagtg taagaatgat aaggtaaggc 240 tattaacttg ctttgtgaac aggctatgtt ctgg 274 <210> 314 <211> 285 <212> DNA <213> HUMAN <400> 314 cagggcccag gaatggctgt ccaagaggaa ggggctggac cgtccactcc ctgggttccc 60 aaccaccctt cccctcctgg tcacctttcg gcttggcatc aggagggctt gaagaagact 120 cctcagcccc acctgcagac ctagctagtt gccaaccacc tggggttgtg cccagtcctc 180 agaactcacc tgcccatggt catccgagcc gttcccacaa aagccttcct tgggatcctc 240 agccgtctgg ggggcctcct tactggggtc acctcaaaaa cagct 285 <210> 315 <211> 249 <212> DNA <213> HUMAN <400> 315 atgatgcgga ggcagggtct gtggaggagc acaagagcgt tatcatgcat ctcttgtcgc 60 aggttagact tggaatggat cttactaagg tagttcttcc aacgtttatt cttgaaagaa 120 gatctctttt agaaatgtat gcagactttt ttgcacatcc ggacctgttt gtgagcatta 180 gtgaccagaa ggatcccaag gatcgaatgg ttcaggttgt gaaatggtac ctctcagcct 240 ttcatgcgg 249 <210> 316 <211> 311 <212> DNA <213> HUMAN: GTTAAACTGACTATTCAGAAAGAGGTGATGAATGGTGCTATCCTTCAACAAGTGTTTGTG GTGGATTATGTTGTTCAGTCCCAAATGTGTGGAGATTGCCATAGAGTAGAAGCTAAGGAT TTCTGGAAGGCTGTGATTCAAGTGAGGCAAAAGACTTTGCATAAAAAAACTTTCTACTAT CTGGAACAGTTAATTCTGAGATATGGAATGCATCAGAATACACTTCGTATCAAAGAGATT CA <3097063H1;DNA;HUMAN <400> 316 gtttgccatt ttctctttcc tgatagagta cagctgagac ccggacactg gttagagggc 60 taggtcgggt gttggccact tggaagataa gattaggttt gccatccatg tgagctacta 120 ctgctatgtc agtaaagcga attgaaaaag ctcgattttt tggccgggca atcttcgcca 180 caaaagcacc taaataagaa attattgatt tttttttaga atgaagactt taaatatcaa 240 tactttttct gaatgacaag tgtatatcaa atatttacac atttcttggt gccatgcctt 300 tcagtgagtc a 311 <210> 317 <211> 288 <212> DNA <213> HUMAN <400> 317 actgaaatac ggaatcaagt taaaaaagag atgatccttg ccaaacgttt tttctttata 60 gtatttactg atgcattatg ctggataccc atttttgtag tgaaatttct ttcactgctt 120 caggtagaaa taccaggtac cataacctct tgggtagtga tttttattct gcccattaac 180 agtgctttga acccaattct ctatactctg accacaagac catttaaaga aatgattcat 240 cggttttggt ataactacag acaaagaaaa tctatggaca gcaaaggt 288 <210> 318 <211> 230 <212> DNA <213> HUMAN <400> 318 caaagttgga gatctgcaac ctcacggccg atgctctgca gtctgacaag cttcagacct 60 ggacagtgtc tgtgaacgag ggccgctggg tacggggttg ctctgccgga ggtcgccgca 120 acttcccaga tactttctgg accaaccctc agtaccgtct gaagctcctg gaggaggacg 180 atgaccctga tgactcggag gtgatttgca gcttcctggt ggccctgatg 230 <210> 319 <211> 546 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(546) <223> N=any base <400> 319 tgcagcccca aatctggagg aattatcacg tcttacagct tgaaagtaca ggtgaaaatg 60 tcaaacctca ccatcaattg anaaacacag tgactgtgga taatactgtg ggcaacgaca 120 ctatgtttct agttacgtgg caggccagtg gtcctcctga gattatatta tttgatcctg 180 atggacgaaa atactacaca aataatttta tcaccaatct aacttttcgg acagctagtc 240 tttggattcc aggaacagct aagcctgggc actggactta caccctgaac aatacccatc 300 attctctgca agccctgaaa gtgacagtga cctctcgcgc ctccaactca gctgtgcccc 360 cagccactgt ggaagccttt gtggaaagag acagcctcca ttttcctcat cctgtgatga 420 tttatgccaa tgtgaaacag ggattttatc ccattcttaa tgccactgtc actgccacag 480 ttgagccaga gactggagat ctgttacgct gagactcctt gatgatggag caggtgctga 540 tgttat 546 <210> 320 <211> 238 <212> DNA <213> HUMAN <400> 320 ttttaaaata tgaaaagaaa ctggccaaaa tgtgcttttt aatgatattc accttcctgg 60 tctgttggat gccttatatc gtgatctgct tcttggtggt taatggtcat ggtcacctgg 120 tcactccaac aaatctattg tttcgtacct ctttgctaaa tcgaacactg tatacaatcc 180 agtgatttat gtcttcatga tcagaaagtt tcgaagatcc cttttgcagc ttctgtgc 238 <210> 321 <211> 253 <212> DNA <213> HUMAN <400> 321 gcctcgtttc tggctggggt ctgctggcga acggcagaat gcctaccgtg ctgcagtgcg 60 tgaacgtgtc ggtggtgtct gaggaggtct gcagtaagct ctatgacccg ctgtaccacc 120 ccagcatgtt ctgcgccggc ggagggcaag accagaagga ctcctgcaac ggtgactctg 180 gggggcccct gatctgcaac gggtacttgc agggccttgt gtctttcgga aaagccccgt 240 gtggccaagt tgg 253 <210> 322 <211> 138 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(138) <223> N=any base <400> 322 gcggggcaga gctgtgggct gcttgtcctg gnnggagatg aagaaagcaa tttccaacct 60 nacaaatccg gcagccccaa antaagccgg gccagcaaga tgaaacaggg caccccagct 120 nccctggtac tnaggttg 138 <210> 323 <211> 218 <212> DNA <213> HUMAN <400> 323 cttctcaagg ccacacgact ggaaagaggc agaacaagga cttcacccga gtcgtctgtc 60 tttttttctg aatgctcgca acgccctggt ggtctccttc gcagccctgg ttgcgtactc 120 cttcgaggtg actggatacc agcctttaat cctaacaggg gagacagctg aggggctccc 180 tccagtccgg atcccgccct tctcagtgac cacagcca 218 <210> 324 <211> 229 <212> DNA <213> HUMAN <400> 324 cccagaggct catcaggact tgtaaacagc agacagaaga gctatgacca ctcaaggcac 60 catcatggga gcagcattgc tggaggactg gtgaaggggg ctttgtctgt tgctgcctct 120 gcatacaagg ccctgtttgc tgggccacca gtcactgcac agccaataat ttctgaagat 180 cagacagcag ccctgatggc ccatctcttt gaaatgggat tctgtgaca 229 <210> 325 <211> 260 <212> DNA <213> HUMAN <400> 325 gcgctgccgc cgccgcgtct gctgaagcct ccgagatgcc ggcgcgtacc gccccagccc 60 gggtgcccac actggccgtc ccggccatct cgctgcccga cgatgtccgc aggcggctca 120 aagatttgga aagagacagc ttaacagaaa aggaatgtgt gaaggagaaa ttgaatctct 180 tgcacgaatt tctgcaaaca gaaataaaga atcagttatg tgacttggaa accacattac 240 gtaaagaaga attatccgag 260 <210> 326 <211> 263 <212> DNA <213> HUMAN <400> 326 ggcacccaga gtacaacaga cccttgctcg ctaacgacct catgctcatc aagttggacg 60 aatccgtgtc cgagtctgac accatccgga gcatcagcat tgcttcgcag tgccctaccg 120 cggggaactc ttgcctcgtt tctggctggg gtctgctggc gaacggtgag ctcacggggt 180 gactctgggg ggcccctgat ctgcaacggg tacttgcagg gccttgtgtc tttcggaaaa 240 gccccgtgtg gccaagttgg cgt 263 <210> 327 <211> 335 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(335) <223> N=any base <220> <221> misc_feature <222> (1)..(335) <223> <400> 327 ggcgcctgcg gtgggtgagc gcacgcgang gcggcgaggc ggcacgtgtt tctaggtcgt 60 ggcgtcgggc ttccggagct ttggcggcag ctaggggagg atggcggagt cttcggataa 120 gctctatcga gtcgagtacg ccaagagcgg gcgcgcctct tgcaagaaat gcagcgagag 180 catccccaag gactcgctcc ggatggccat catggtgcag tcgcccatgt ttgatggaaa 240 agtcccacac tggtaccact tctcctgctt ctggaaggtg ggccatccat ccggcaccct 300 gacgttgagg tggatgggtt ctctgagctt cggtg 335 <210> 328 <211> 246 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(246) <223> N=any base <400> 328 gtgtagcaag aggcagattt ttggtgccaa atagatttga atcctggttc tgcttcttcc 60 tttgtagagt atgatattgg ntctttcctc ccaaagctat tataaagact aaatatgtac 120 acaaatcttt ggggatgtct gacatataaa tgcttaacaa taggtatttg ctggtattat 180 tacaaatgaa tttgcttatt tttgagccac ttctatgtct gtccattaaa ccaaaatgtg 240 ttctgc 246 <210> 329 <211> 254 <212> DNA <213> HUMAN <400> 329 cccctccaaa aacccagcca acagaggaca acaagttcaa attctgtttg agctgtgccc 60 gtttggctga gatgaggcaa aaagaaatcc ccagggtcct ggtgcagctc gaggacctgg 120 atagccgggt cctctactac tcagccacca agaacggcat cctgtaccga tttggtgatg 180 gtgtgtacct gccccctgag gccttcacgt tcaacatcaa gctgtccagt cccgtgaaac 240 ggccacggaa ggag 254 <210> 330 <211> 546 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(546) <223> N=any base <400> 330 gctgggcaat gacatcgccc ttatgaagct ggccgggcca ctcacgttca atgcagaaat 60 gatccagcct gtgtgcctgc ccaactctga agagaacttc cccgatggaa aagtgtgctg 120 gacgtcagga tggggggcca cagaggatgg aggtgacgcc tcccctgtcc tgaaccacgc 180 ggccgtccct ttgatttcca acaagatctg caaccacagg gacgtgtacg gtggcatcat 240 ctccccctcc atgctctgcg cgggctacct gacgggtggc gtggacagct gccaggggga 300 cagcgggggg cccctggtgt gtcaagagag gaggctgtgg aagttagtgg gagcgaccag 360 ctttggcatc ggctgcgcag aggtgaacaa gcctggggtg tacacccgtg tcacctcctt 420 cctggactgg attcacgagc agatggagag agacctaaaa ancttgaaga ggaaggggac 480 aagtagccac ctgagttcct gaggtgatga agacagcccg attctcccct ggactcccgt 540 gtagga 546 <210> 331 <211> 506 <212> DNA <213> HUMAN <400> 331 atctggagca catgaattgg ataggctgaa aattatattc atagatctga atataatgat 60 ctgaaagtgg cagtactatc agaaaaaaac cctgtgaggc ttattttggt aatacaattt 120 acttataaag gctgaatcaa caataaaaag ttgtggtctt attttaatga aataaaagca 180 gagaaacaaa aaaatgcatg ccctcctaca tccctgacta tattgaacca taaacattcc 240 tatcatgttt taaaatagat attacaaatc ctatagagca tgcaattggt tttaaaaggc 300 taaagactaa attagaaaac tcattagcag aattaaatat gatgttggga ttgcccatct 360 cgcctgacca tgctgtgatg tgtcacacga ttcagcagag agcagctggg caagtctagc 420 acttccttgc catggccggg gaaggaacat agctgagtag catgcaggcc agtcaaaatt 480 catttaggaa cgtgattgta catgta 506 <210> 332 <211> 502 <212> DNA <213> HUMAN <400> 332 gtgagttaca cttcttcctc cccaccaggt gctctctgca gctctggaaa aatggtgtcc 60 tctttgttgt cccaccaggg ggcgccacct ccagccccgc cccagcctca tacccagttc 120 ttcagctcgg ccagcggtaa ctgaagcctc ccagaatcct ggatccgggc ccctagtacc 180 ctctttccca gggacccagg agtcctgcct ccagtcgcct gcacttgtaa ctgagagctg 240 gaggtcgtcc atagcagcat agtgagagtg tttttgatga gggtatgcag agtgggggtg 300 accatgttcc cacctggggc ctcaggtggg ccaaggccta cccactttag ccagcgtccc 360 ctccagcagc catcagcaag ccaacccact ccaagccagg gccccctttg gtccttgcac 420 ttgaggtgct ttgttcaggg ctgggtcagg agtggcagag acgatgtcca acaacctcag 480 tactggggga aaagtagcct gg 502 <210> 333 <211> 405 <212> DNA <213> HUMAN <400> 333 actgggcata attttcctca ttatctacag cctttaccct gaacaatgga gtttaatcac 60 caaaaaaatt agatactagg gctccagatg ataggatggc ccaagttatt taacgttttc 120 ttgtttaaaa ggtgggccca ttggcactta agaaaataaa tcagaaaata atatggcttc 180 aagtggacaa ataaatatga atttctaagg aagtcttcgc attatctatt ggtttcctct 240 tgatttggtt ccatggataa tttctctcca agttctctaa taagttctgc taggtcttct 300 gtattctgag atttttcttc aaggagttca tagcggagac ttgagatgtc ctgcttaatt 360 tccttcagtt ccccttcgtt cacttcatca ctctccttat ctatc 405 <210> 334 <211> 191 <212> DNA <213> HUMAN <400> 334 attcttcact cctgctccaa gggctgggct gtgggtggga tactgggatt ttgggccact 60 ggattttccc taaatttgtc ccccctttac tctccctcta tttttctctc cttagactcc 120 ctcagacctg taaccagctt tgtgtctttt ttccttttct ctcttttaaa ccatgcatta 180 taactttgaa a 191 <210> 335 <211> 214 <212> DNA <213> HUMAN <400> 335 atcgagatcc tgcgcgacga cgtggtcgtg gccatcctag gaaagaatga catctttggg 60 gaacccgtca gcctccatgc ccagccaggc aagtccagtg cagacgtgcg ggctctgacc 120 tactgcgacc tgcacaagat ccagcgggca gatctgctgg aggtgctgga catgtacccg 180 gcctttgcgg agagcttctg gagtaagctg gagg 214 <210> 336 <211> 532 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(532) <223> N=any base <400> 336 ccggtgtttg gactctacac ttctttcttc cccgtcctca tctacagctt gctaggtact 60 gggagacacc tgtccacagg aactttcgcc atactcagcc tcatgacagg ctcggccgtc 120 gagcggctgg tgccggancc cctcgtgggg aatctgagcg gaatcgagaa ggagcagctg 180 gacgctcaac gggttggggt agccgcggcc gtggccttcg ggagcggggc gttgatgctg 240 gggatgttcg tgctgcagct cggcgtcttg tccacctttt tgtccgagcc tgtggtcaag 300 gcgctgacca gcggggccgc gctgcacgtg ctcttgtccc agctgccgag cctcttgggg 360 ttgtccctcc cgcgccagat cggctgcttc tctctcttca anacgctggc ctccttgctg 420 actacgctgc ctcggancag tccggccgaa ctgaccatct ccgcgctcag cctggcgctg 480 ctcgtgccgg taaagggaat tgaacgtgag attccgagac cggctaaccc ac 532 <210> 337 <211> 452 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(452) <223> N=any base <400> 337 acagatccta agccgccccc gcccgcctgc tcggacagtt tccgttccct cctagtctct 60 gttcgctcgc ttaagctgtt ttgaagccaa gtgaagagtg tggtttgcat ccaagagaaa 120 acaccacact gtgatgtcat cgggaaatga tctcccaagt cgctgccaga caccacccac 180 tgcttcgccg gacaatgtcg aagtccagtc tgtgccgggg aaggcactgg ttaggaagga 240 tgttcaaacg gtcccaccca agcctgtcac ctctgctcat cctccaagac cacccagctt 300 tctcccagcc acagccaaga ttcccaaagt caaggcccaa agatttccaa ggttcccaaa 360 gtcaaggcca ggccaaggcc tggttgggtc cttggggcgg gcaagggcgg nctcttcctc 420 tgctgagaat ccccacttgg tgtaagggga ga 452 <210> 338 <211> 349 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(349) <223> N=any base <400> 338 ctttttttga ggtttggatg ttgcagctag taaaggatat ttttgctctg ttcagcagtt 60 ctaaaaattg ctgaagtagg ggccaggtca ctggtagtta tagtatggaa tgggagaagt 120 gaaagttcag ttatagaact ttccatactt ccaagtttac tgcaagtttt tatgcttgag 180 agagatgctt tctaatataa gactgatgtg ttgattttac tgattgtact gtacatctat 240 taaagcctta gattattaca ttacgggttg gaacccatac caatgtaatt tcaatcgtgt 300 taagaaagta atngtgactt cacatgttat tgtagttagt tacattata 349 <210> 339 <211> 261 <212> DNA <213> HUMAN <400> 339 atttgaaaaa atgtatttaa aagtccaaca actttttaat ataaattacg actctcaaac 60 ccattcccat cactttatta gtgatggtag catacatatt agagaaggta gctaaaggca 120 agagagcacc aaaggaaaaa gactgtccaa agaacaggta ttagaatgag gccgaagatc 180 acggtgacca gagatttcta ggagtctcta acctttccac cctatcctgt taacccttta 240 gatctctagt ataacactca g 261 <210> 340 <211> 224 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(224) <223> N=any base <400> 340 tgtacatcta ttaaagcctt agattattac attacgggtt ggaacccata ccaatgtaat 60 ttcaatcgtg ttaagaaagt aatggtgact tcacatgtta ttgtagttag ttacattata 120 gaatattact tattttcttt gttaaaatgt agtttttcat ttcctacatt tattagattt 180 tcattttcta ttaacaattg aataccattt catnttatag actt 224 <210> 341 <211> 479 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(479) <223> N=any base <400> 341 tgcaaatatg tagtccaaaa caacaaaaaa agaaaatgtc ttatgtgact tagcacgaac 60 agtttccaca gcctttcaca ctattgacaa tttcttcttg tagtttcttt ctttcctcct 120 ctttggatat attttctttc tttgcttccc atttggggtt atcatggttc tgcacacggc 180 tgctctgtgt atgccacatt tctgaataga tactatgagg gttagcaagc aaaccatggt 240 gggtaccacg ttcggctacc ttaccctgat ccaagacaat gatttcatct gcatcaacca 300 ctgttgacaa tctgtgtgca atgaaaatag aagttctgtg tttgaccaca tccttcatgg 360 caccaagaat agtctcttca gtaatcgaat ctaacgatga agtagcttca tcatagagta 420 tgactggggg ggccttcaaa atggntcttg caattgctaa ctctttggct tttctcctc 479 <210> 342 <211> 246 <212> DNA <213> HUMAN <400> 342 gttataacta atctgcctga agacttctca tgatggaaaa tcagccaagg actaagcttc 60 catagaaata cactttgtat ctggacctca aaattatggg aacatttact taaacggatg 120 atcatagctg aaaataatga tactgtcaat ttgagatagc agaagtttca cacatcaaag 180 taaaagattt gcatatcatt atactaaatg caaatgagtc gcttaaccct tgacaaggtc 240 aaagaa 246 <210> 343 <211> 447 <212> DNA <213> HUMAN: TGGATGTTCGTGGAATTGCTGATCCATCCAAGGGCGTCCTTTGGAGCCAGTGGAGCCTGC CGGCGCATCTGAGGGGCAGAATGCTGCTAGCACTTGAATCTGGGATCTCGCCTTATTCTC AAGTAGCAAGGCATCTCGACAAGCATGGTCTAGGTCTGGTGGCCAGCTTGCCAGTACCTG AGCCGGTCGGGTCATCTGCCTCTGAGGGACCGTCCTCACCGAG <1525902F6;DNA;HUMAN <400> 343 ggagctgttc ctgaaggttg ccggcctggg ccctgtggag tacttgtctt ccggatggaa 60 cttgtttgac ttctccgtga cagtgttcgc cttcctggga ctgctggcgc tggccctcaa 120 catggagccc ttctatttca tcgtggtcct gcgccccctc cagctgctga ggttgtttaa 180 gttgaaggag cgctaccgca acgtgctgga caccatgttc gagctgctgc cccggatggc 240 cagcctgggc ctcaccctgc tcatctttta ctactccttc gccatcgtgg gcatggagtt 300 cttctgcggg atcgtcttcc ccaactgctg caacacgagt acagtggcag atgcctaccg 360 ctggcgcaac cacaccgtgg gcaacaggac cgtggtggaa gaaggtacta ttatctcaat 420 aattttgaca acatcctcaa cagcttt 447 <210> 344 <211> 97 <212> DNA <213> HUMAN <400> 344 agctgcctga gccagccagt gacagcgttt cctcagggca cttggattgg tgaagacata 60 ttccctcctc tgctgcctcc cactgtaatc aggacct 97 <210> 345 <211> 210 <212> DNA <213> HUMAN <400> 345 cacagatgaa ggacgtgttc ttcttcctct tcttcctcgg cgtgtggctg gtagcctatg 60 gcgtggccac ggaggggctc ctgaggccac gggacagtga cttcccaagt atcctgcgcc 120 gcgtcttcta ccgtccctac ctgcagatct tcgggcagat tccccaggag gacatggacg 180 tggccctcat ggagcacagc aactgctcgt 210 <210> 346 <211> 437 <212> DNA <213> HUMAN <400> 346 atgagaacgg ctacaacttc aagtccgaca tctggtcctt gggctgtctg ctgtacgaga 60 tggcagccct ccagagcccc ttctatggag ataagatgaa tctcttctcc ctgtgccaga 120 agatcgagca gtgtgactac cccccactcc ccggggagca ctactccgag aagttacgag 180 aactggtcag catgtgcatc tgccctgacc cccaccagag acctgacatc ggatacgtgc 240 accaggtggc caagcagatg cacatctgga tgtccagcac ctgagcgtgg atgcaccgtg 300 ccttatcaaa gccagcacca ctttgcctta cttgagtcgt cttctcttcg agtggccacc 360 tggtagccta gaacagctaa gaccacaggg ttcagcaggt tccccaaaaa gctgcccagc 420 cttacagcag atgctga 437 <210> 347 <211> 134 <212> DNA <213> HUMAN <400> 347 ccgctgacag aggagctggt gttccgggcc tgtatgctgc ccatgttagc accgtgcatg 60 ggcctgggcc tgctgtgttc acctgcccgc tcttttttgg agttgcccat tttcaccata 120 ttattgagca gctg 134 <210> 348 <211> 239 <212> DNA <213> HUMAN <400> 348 gtcaaggaga agtccataag gatcatcatc acgctgctgg tgcaggtgct cgtctgcttt 60 atgcccttcc acatctgttt cgctttcctg atgctgggaa cgggggagaa cagttacaat 120 ccctggggag cctttaccac cttcctcatg aacctcagca cgtgtctgga tgtgattctc 180 tactacatcg tttcaaaaca atttcaggct cgagtcatta gtgtcatgct ataccgtaa 239 <210> 349 <211> 472 <212> DNA <213> HUMAN <400> 349 cagaggcttg gaggggatgt gcagagcccc aactgcccat ctgaggatgt agtcatcact 60 ccagaaagct ttggaagaga ttcatccctc acatgcctgg ctgggaatgt cagtgcatgt 120 gacgccccta ttctctcctc ttccaggtcc ctagactgca gggagagtgg caagaatggg 180 cctcatgtgt accaggacct cctgcttagc cttgggacta caaacagcac gctgccccct 240 ccattttctc tccaatctgg aatcctgaca ttgaacccag ttgctcaggg tcagcccatt 300 cttacttccc tgggatcaaa tcaagaagaa gcatatgtca ccatgtccag cttctaccaa 360 aaccagtgaa gtgtaagaaa accccagaac tgaacttacc gtgagcgacc aaagatgatt 420 taaaaaggga agtctagagt tcctagtctc cctaacagca ccagagaaga ca 472 <210> 350 <211> 288 <212> DNA <213> HUMAN <400> 350 gctcgcgtcg catttggccg cctccctacc gctccaagcc cagccctcag ccatggcatg 60 ccccctggat caggccattg gcctcctcgt ggccatcttc cacaagtact ccggcaggga 120 gggtgacaag cacaccctga gcaagaagga gctgaaggag ctgatccaga aggagctcac 180 cattggctcg aagctgcagg atgctgaaat tgcaaggctg atggaagact tggaccggaa 240 caaggaccag gaggtgaact tccaggagta tgtcaccttc ctgggggc 288 <210> 351 <211> 384 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(384) <223> N=any base <400> 351 tttggtcaag ttgtttccat taaaaagtac tgattttaaa aactaataac ttaaaactgc 60 cacacgcaaa aaagaaaacc aaagtggtcc acaaaacatt ctcctttcct tctgaaggtt 120 ttacgatgca ttgttatcat taaccagtct tttactacta aacttaaatg gccaattgaa 180 acaaacagtt ctgagaccgt tcttccacca ctgattaaga gnggggnggc aggcantagg 240 ganaanagtc anttngcctt cnnagcnttc tgggcagacn tggcgaccnc nncagcncna 300 gcagccntct cgtccacggc tntgtntgac acccaccgca acggncngnc tctatancac 360 gaacagcaaa gcgacccaaa ggng 384 <210> 352 <211> 256 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(256) <223> N=any base <400> 352 gggtgaaggt ggcttcgggg gtcgtggtgg aggcagaggc ggctttggag gacgaggtgg 60 tggtagagga ggccgaggag gatttggtgg cagaggccgg ggaggctttg gagggcgagg 120 aggcttccnn nnnnnnnnnn nnnnnnnnnn nnaccacaag ccacaaggaa agaagacgaa 180 gtttgaatag cttctgtccc tctgctttcc cttttccatt tgaaagaaag gactctgggg 240 tttttactgt tacctg 256 <210> 353 <211> 298 <212> DNA <213> HUMAN <400> 353 cttctttatg gcgtcgctcc tgtgctgtgg gccgaagctg gccgcctgcg gcatcgtcct 60 cagcgcctgg ggagtgatca tgttgataat gctcggaata tttttcaatg tccattccgc 120 tgtgttgatt gatgacgttc ccttcacgga gaaagatttt gagaatggcc cccagaacat 180 atacaacctt tacgagctag tcagctacaa ctgtttcatc gctgcaggcc tttacctcct 240 cctcggaggc ttctctttct gccaagttcg gctcaataag cgcaaggaat acatggtg 298 <210> 354 <211> 540 <212> DNA <213> HUMAN <400> 354 gaggaacagc gccatgtgct ccgggctcct ggagctcctg ctgcccatct ggctctcctg 60 gaccctgggg acccgaggct ctgagccccg cagtgtgaac gatcccggga acatgtcctt 120 tgtgaaggag acggtggaca agctgttgaa aggctacgac attcgcctaa gacccgactt 180 cgggggtccc ccggtctgcg tggggatgaa catcgacatc gccagcatcg acatggtttc 240 cgaagtcaac atgagattct ggctgcagga aaggggaacg aagacagtgg tctgtgcgtt 300 ccaggggtgt ctctgcggtt tttccaaggc tgcctcctgg actgggagac ccgggcccgg 360 caccgccagt ctctgtccga ggtgctgaca ggcttccgct gcttcagaga gcgggaggcc 420 gcgcctaggc gggctctcag aggagccgct ctaccgggag agtcggaggc tggtgaccca 480 gtgtcactta ggtcttctgt gaatgcagac tggattcaat attctgacct gtgggaagcg 540 <210> 355 <211> 508 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(508) <223> N=any base <400> 355 aagaggacca atgaaaaggg tgccttctgg ggcctgatct cgggcctgct cctgggcttg 60 gttaggctgg tcctggactt tatttacgtg cagcctcgat gcgaccagcc agatgagcgc 120 ccggtcctgg tgaagagcat tcactacctc tacttctcca tgatcctgtc cacggtcacc 180 ctcatcactg tctccaccgt gagctggttc acagagccac cctccaagga gatggtcagc 240 cacctgacct ggtttactcg tcacgacccc gtggtccaga aggaacaagc accaccagca 300 gctcccttgt ctcttaccct ctctcagaac gggatgccag aggcnnnnnn nnnnnnnnnn 360 gtccagttcg agatggttca agaaaacacg tctaaaancc acagctgtga catgacccca 420 aagcagtcca aagtgtgaan gccatctgtg gntctgtgga atacaggaga agggcaaagn 480 agagctcccg gcnagagcag aagcnatc 508 <210> 356 <211> 553 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(553) <223> N=any base <400> 356 ttcaggagtg ggcgaantct atgagtttgt tcacagtttt caggatgaga agcgtcantg 60 gncttaccag gttttgggcc tctcagaagg ggcaacaaat gaagaaatac atcggagtta 120 ccaggagcta gtgaaggtct ggcacccaga ccacaacctg gaccagacag aggaggcaca 180 gaggcacttc ctggagatcc aggctgcgta tgaagtcctg agtcaaccca ggaagccctg 240 gggatcccgg aggtgaaaag aaacttcccc ctgaggactg actcttccta gcagagctgg 300 gcaacttgtc ccaaatctag ctttgcccac gaatggcatc ccaacagagt taaagaaact 360 gcttgcaggg gctgggcgtg gtnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 420 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 480 nnnnnntgga tatattttaa tttactcaaa tgggaactac tgataagcag ttcttatttt 540 tccagcataa gca 553 <210> 357 <211> 574 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(574) <223> N=any base <400> 357 tgctataagc aaaaacatcc aattgggtga tgagaagggc ttaaaattcc cctctgtttg 60 ggactggtct ctccagttta cagcaaagga tcgcaccctt ttccataacc ccttctacat 120 tggaaagagc acaccttgta tacagaatgg ctccgtgaag tcttttaaac ggacaaaggt 180 aaatcacagc taacaaaacg tgatgttggc tcacacgtaa ccaaacacct ctttttcaga 240 acagagagcg ttaaaagtaa aggcagttcc aagagtaaca ctgctaatgt gggtttctga 300 ggggtcattc cctttttaac tcaaatgact gtatcccaac tttcttcctg gtgtctgagg 360 cccacaaagt ctcagtacct gagagtgggc agattgcagc tttgagcctg caagcctgat 420 ttactaaagc cccatttatc catttcttga tgattcaagc cgccactgtg gcagggaatg 480 ccgcctggct gtgatgtagt catggcctcc tgactgctat antcttgtcc taataacatt 540 cattggttgn ccttttaata antccccaat aaat 574 <210> 358 <211> 261 <212> DNA <213> HUMAN <400> 358 gcccctgcct gcctgcctca acccactgct gtacctgctc ttcaaccccc acttccggga 60 tgaccttcgg cggcttcggc cccgcgcagg ggactcaggg cccctagcct atgctgcggc 120 cggggagctg gagaagagct cctgtgattc tacccaggcc ctggtagcct tctctgatgt 180 ggatctcatt ctggaagctt ctgaagctgg gcggccccct gggctggaga cctatggctt 240 cccctcagtg accctcatct c 261 <210> 359 <211> 201 <212> DNA <213> HUMAN <400> 359 taaacatccc aaaactggag ttttcgaaga gaaacatgcc aaacctccag atgtagacct 60 taaaaagttc tttacagaca ggaagactca tctttatacc cttgtgatga atccagatga 120 cacatttgag gtgttagttg atcaaacagt tgtaaacaaa ggaagcctcc tagaggatgt 180 ggttcctcct atcaaacctc c 201 <210> 360 <211> 286 <212> DNA <213> HUMAN <400> 360 ccgccgccga cgccgcttgt gggcccgact ccgctctgtc tgcttcgcca ccttctcccc 60 gagcactgcc cggccggccg ccatggctaa cgtggctgac acgaagctgt acgacatcct 120 gggcgtcccg cccggcgcca gcgagaacga gctgaagaag gcatacagaa agttagccaa 180 ggaatatcat cctgataaga atccaaatgc aggagacaaa tttaaagaaa taagttttgc 240 atatgaagta ctatcaaatc ctgagaagcg tgagttatat gacaga 286 <210> 361 <211> 288 <212> DNA <213> HUMAN <400> 361 tggcgtggcc tcagggctct gcgtgctggc cagctggctc accgccttcg tcctcaccaa 60 gtccttcctg ccagtggtta gcaccttcgg cctccaggtg cctttcttct tcttcgcggc 120 catctgcttg gtgagcctgg tgttcacagg ctgctgtgtg cccgagacca agggacggtc 180 cctggagcag atcgagtcct tcttccgcac ggggagaagg tccttcttgc gctaggtcaa 240 ggtccccgcc tggagggggc caaaccccca gtggctgggc ctctgtgt 288 <210> 362 <211> 175 <212> DNA <213> HUMAN <400> 362 atcacacacg aagagagcca tcttccagaa ataagtttat acactctctc ctctaattgc 60 atcaggactt taccagataa tgttcttcca gatctgaaaa ggaaaatgcc taaaagagct 120 tccaaactca tttttgaata atactaggct acaaagaatt acactgtgaa ttcat 175 <210> 363 <211> 271 <212> DNA <213> HUMAN <400> 363 aggcttgaca ccaagcacgt gcctgcctcg tcaggctaca acttcaggtt tgccaaatac 60 tacaagatca atggcaccac cacccgcacg ctcatcaagg cctacgggat ccgcattgac 120 gtcattgtgc atggacaggc cgggaagttc agcctgattc ccaccattat taatctggcc 180 acagctctga cttccgtcgg ggtggtaagg aaccctctct ggggtcccag cgggtgcggg 240 gggtccacca ggcccttaca caccggtctc t 271 <210> 364 <211> 234 <212> DNA <213> HUMAN <400> 364 ctgtcaccag gagagcacgc caaggacgaa tatgtgctat actattactc caatctcagt 60 gtgcctattg ggcgcttcca gaaccgcgta cacttgatgg gggacaactt atgcaatgat 120 ggctctctcc tgctccaaga tgtgcaagag gctgaccagg gaacctatat ctgtgaaatc 180 cgcctcaaag gggagagcca ggtgttcaag aaggcggtgg tactgcatgt gctt 234 <210> 365 <211> 447 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(447) <223> N=any base <400> 365 angnncngga catgnanctg anagntannn naanggggtn naaggantgn ncaaatncng 60 acnctagcag ggatgtgnnc actgtcangg ggccagnata actgnggntg ttgaagancc 120 tcttttcctc agtntggntc ttctgccanc agtcagatgc anggangccc ggtgcagaag 180 caccaggcac taataatcag gagaggcatg gctagattcc actcacttcc aacatttnct 240 tctggtctct tttcttaggg actcacccct ttggttggga acattctcca gcagtacagc 300 cacaganggg ccagagatgc cagaagcagc agaatccaga cacccaagag catggcctga 360 agggttctga acaaggcctt cagcatgtcc catgaaggaa gtacataggt gtaagcttct 420 gactttcttc tggactcttg agtgggg 447 <210> 366 <211> 305 <212> DNA <213> HUMAN <400> 366 cgcagccgcc cgccgcccgc gccgccatgg gagtggaggg ctgcaccaag tgcatcaagt 60 acctgctctt cgtcttcaat ttcgtcttct ggctggctgg aggcgtgatc ctgggtgtgg 120 ccctgtggct ccgccatgac ccgcagacca ccaacctcct gtatctggag ctgggagaca 180 agcccgcgcc caacaccttc tatgtaggca tctacatcct catcgctgtg ggcgctgtca 240 tgatgttcgt tggcttcctg ggctgctacg gggccatcca ggaatcccag tgcctgctgg 300 ggacg 305 <210> 367 <211> 625 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(625) <223> N=any base <400> 367 ctggaagact tagacaatgc taaggaaaaa tttaatgatg gaaatatcga caaatattca 60 acatcattta aaaacaaagt agcttctctt atttcacata gcttagtttg ggatagaaat 120 agaactaatg tttacaatga ttcttacatt tagcattaat cagaaacgag ggtttgttaa 180 gtgcccttgc tgnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 240 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngt 300 ttgagaaccg ctggattgat tctttgacag tttttgaagt ccgctgctca ccatatcact 360 tcatcctctt ataaactttc actatgtgat tgcctaagag cccctgcttg ttggctgctc 420 cacattttca cacagttgta ctatttcttt ctgaaatgac attgtttgag ggacagtggg 480 tggaacgtgt gagctcctca ctgaaggctg cctccagaat tccctgaatg gactgccttg 540 ctttcttcct aaaatctttc cccaagaggg cataaaggaa gggattaaag caactattgg 600 cagatgctag agcaatgcat acatg 625 <210> 368 <211> 611 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(611) <223> N=any base <400> 368 caatgctaag gaaaaattta atgatggaaa tatcgacaaa tattcaacat catttaaaaa 60 caaagtagct tctcttattt cacatagctt agtttgggat agaaatagaa ctaatgttta 120 caatgattct tacatttagc attaatcaga aacgagggtt tgttaagtgc ccttgctgnn 180 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 240 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnngtttga gaaccgctgg 300 attgattctt tgacagtttt tgaagtccgc tgctcaccat atcacttcat cctcttataa 360 actttcacta tgtgattgcc taagagcccc tgcttgttgg ctgctccaca ttttcacaca 420 gttgtactat ttctttctga aatgacattg tttgagggac agtgggtgga acgtgtgagc 480 tcctcactga aggctgcctc cagaattccc tgaatggact gccttgcttt cttcctaaaa 540 tctttcccca agagggcata aaggaaggga ttaaaggcaa ctattggcag atgctaggag 600 caatgcatac a 611 <210> 369 <211> 240 <212> DNA <213> HUMAN <400> 369 gtggtcgggg gagcggccgg agaggagctg ccgggagttc gtgccctgca ggacatgaca 60 ccagtggcat atcacggcca tggggtctca gcattccgct gctgctcgcc cctcctcctg 120 caggcgaaag caagaagatg acagggacgg tttgctggct gaacgagagc aggaagaagc 180 cattgctcag tacccatatg tggaattcac cgggagagat agcatcacct gtctcacgtg 240 <210> 370 <211> 215 <212> DNA <213> HUMAN <400> 370 ggctgcttcc tagaaggtcg tgtcacgtgg aacctcttaa tctcagcatc cggagctcca 60 ggaagggaaa atttcaagtc agatagaatt ctatatatac catttctttg gaaccttcag 120 ccctcaagat tccaacatca tgacctcagt ttcaacacag ttgtccttag tcctcatgtc 180 actgcttttg gtgctgcctg ttgtggaagc agtag 215 <210> 371 <211> 116 <212> DNA <213> HUMAN <400> 371 aaagttttgg caggagcggg agaattctgc ggagctgcgg gacggcggcg gtggcgccgt 60 aggagccggg acagtgttgt acagtgtttt gggcatgcac gtgatactca cacagt 116 <210> 372 <211> 225 <212> DNA <213> HUMAN <400> 372 gagaaccaga gtgtcagagc aaaacctcct ctatctgcac atcctgggga cgaaccgggc 60 agccggagag ctgcggccgg cccagtcccg atccggcttt gaagggtaaa acccaaggcg 120 gggccttggt tctggcagaa gggacgctat gaccgcagaa ttcctctccc tgctttgcct 180 cgggctgtgt ctgggctacg aagatgagaa aaagaatgag aaacc 225 <210> 373 <211> 505 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(505) <223> N=any base <400> 373 gtcagtgcat gtgacgcccc tattctctcc tcttccaggt ccctagactg cagggagagt 60 ggcaagaatg ggcctcatgt gtaccaggac ctcctgctta gccttgggac tacaaacagc 120 acgctgcccc ctccattttc tctccaatct ggaatcctga cattgaaccc agttgctcag 180 ggtcagccca ttcttacttc cctgggatca aatcaagaag aagcatatgt caccatgtcc 240 agcttctacc aaaaccagtg aagtgtaaga aacccagact gaacttaccg tgagcgacaa 300 agatgattta aaagggaagt ctagagttcc tagtctccct cacagcacag agaagacaaa 360 attagcaaaa ccccactaca cagtctgcaa gattctgaaa cattgctttg accactcttc 420 ctgagttcag tggcactcaa catgagtcaa gagcatcctg cttctaacat gtggatttgg 480 tcacaaggnt taaggtgacc caatg 505 <210> 374 <211> 250 <212> DNA <213> HUMAN <400> 374 gcgactatat ggatgaggtg acatatgggg agctggagaa ggaggaagct cagcccattg 60 tcactaagta caaggaggtg gcagaggtgg tggcagaggc ggtggtttta gaggtggaag 120 aggaggtgga ggtgggggct tcagaggagg aagaggtggt ggtttcagag ggagaggaca 180 ttaagtgaaa cagttgacag acatcaccag ttgacttctg cattaacctg catgatctgt 240 ttctactatg 250 <210> 375 <211> 242 <212> DNA <213> HUMAN <400> 375 atttgtttag agtatctata gcaaaatagg ttacatgtag tttgaaataa ggtatcctga 60 gttactttgg caacaagttc ttttaccctt acccgtggta tttgaaaaaa atcaaggtaa 120 ctgtctgaat actttaatat cagcttgttt tgtgaattct ctgaatactg tcaacactct 180 tatctaagtt tgcctttatg atgcagtggc agcattttga attacttttc aaagaatact 240 gt 242 <210> 376 <211> 286 <212> DNA <213> HUMAN <400> 376 cagagaggtc gtggaggtgg atctggcaat tttatgggtc gcggagggaa ctttggaggt 60 ggtggaggta attttggccg tggtggaaac tttggtggaa gaggaggcta tggtggtgga 120 ggtggtggca gcagaggtag ttatggagga ggtgatggtg gatataatgg atttggaggt 180 gatggtggca actatggcgg tggtcctggt tatagtagta gagggggcta tggtggtggt 240 ggaccaggat atggaaacca aggtggtgga tatggtggag gtggag 286 <210> 377 <211> 627 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(627) <223> N=any base <400> 377 tttatcaaat aaaactatga aaatgcaagt gggctcctat gccagaaaaa cccacctggc 60 gttccagatg caagagggcc agagcagagg cctggttctg gggaagcctc aggatgctgc 120 ccaccaagga gtgatttcca aagagtaatc cagggtgccc ttttcccttc tggggaagtg 180 tggagaggta gagccccaga ggagaatgta aacaagcagc cagcacctct gtataggccc 240 ggcctggatc agagagaggg gagaactctg cagggtgtgg gattgggctc agggacctcc 300 gagtgaggca gggactccct gctggctgct ctgcagcagc tgctggaaca gggagtgggg 360 ctggttgcgc agggtggccg gggagtccag ctctaccact ctccccgctt gtagcaccag 420 cacccggtct gagttcagga tcgtgttgag cctatgggca atggtcagca ctgtcttgtt 480 ggcaaagcgt ttgcagatgg tctgctggag cagctggtct gtcttctggt ccacacttgc 540 tgtggccttc atcgatacac aggatcttgg catctgtgaa gagaancctg gccaaacaca 600 acagctgcct ctgccccaag aagataa 627 <210> 378 <211> 170 <212> DNA <213> HUMAN <400> 378 ttccgggaag ttcaatagtg gtgagttggt ggccattatg ggtccttccg gggccgggaa 60 gtccacgctg atgaacatcc tggctggata cagggagacg ggcatgaagg gggccgtcct 120 catcaacggc ctgccccggg acctgcgctg cttccggaag gtgtcctgct 170 <210> 379 <211> 290 <212> DNA <213> HUMAN <400> 379 gctgcaccgt gagcgccgag gacaaggcgg cggccgagcg ctctaagatg atcgacaaga 60 acctgcggga ggacggagag aaggcggcgc gggaggtgaa gttgctgctg ttgggtgctg 120 gggagtcagg gaagagcacc atcgtcaagc aggtgtaggt cattcccggg ggttgcttat 180 tccggggggg attcccgcag tacgcgcggt tgtctacagc aacaacatcc agtccatcat 240 ggccattgtc aaagccatgg gcaacctgca gatcgacttt gccgacccct 290 <210> 380 <211> 400 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(400) <223> N=any base <400> 380 agcctctgna gggtaaactt ttatttcttg gcctgnacag gnacttccac acccatgcct 60 cctcctgggc accttttact ctgcccaagc agtggcagnc ccagttccaa aaggtgcctg 120 ccatggncca aaggggttgg ggagtcactt cacattccag gttggaggag tgagaggact 180 tgggggtact cctcccaccc cattgccagc aagaggccat gactcacctc aaccccaagt 240 cctgcatcct gggtgggaag tgacaatgcc tcctcccagc tntccatacc taatggggtc 300 atgaccagac agggtaggac ccaggccccc agcttcagtt ggtaacggtg gcctccacgg 360 ctgccccctg tccaggtgac aaccccagcc cccatgatgg 400 <210> 381 <211> 407 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(407) <223> N=any base <400> 381 atagagaacc cacagttcag ttttattcag agcaaagaaa aaagaaactt tccatcatac 60 tagaagaaac ttggccgtaa gtttgggatc tgtgctcaaa ctacacatgc aatgaggaca 120 atattctgct aatacaattg acttgctgct gcatttgtct actgtttgtc taatattaac 180 aattataaac agagcagtgc aactagtatt tggaacaatc cttacagtgt tacagtgtca 240 ggcacaacat ttcacttctc ttcacaccac tggttctctt tgcgtacctg ggcttcctcc 300 tcttcagtaa agtcattttt gatattgaag gtcttgcgaa tctcctcagg agttttcccc 360 ttgatcatat tggcaacagt cttgcatgta acatcaagca aaccttn 407 <210> 382 <211> 456 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(456) <223> N=any base <400> 382 gtagtcagct atttaattag gttcttaaga catttagaac accaatttgt gaggataaat 60 tccattcgtc agagcaaaca cagatcgcag gtagccctgg agctgaggaa tagctttgat 120 ttttggtaaa atttgtgagt ccacagcttt ctgatcaatc ttgcgctgct ccgtaatctc 180 atatttctct ttttctgtgt cgaagatctc accttcctgg tgtctgggct tccgcagctt 240 cttcttcttg aagtaagcat cagtaagatg ttttgggatt tttacattgc tgatatcgat 300 tttggttgaa gtggcaatga caaatttctg gtgtgttctt cgtagaggaa ctcgattgag 360 gaccagaggc gntncaacaa gtaataagcc actagccagc tgcttcagga aaaccaccct 420 cttgcccctg tggcgtccag tgaggatgat cagaat 456 <210> 383 <211> 554 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(554) <223> N=any base <400> 383 taatactaag ggaaaaggct gttcttttat ttatttattt ttcctgagtc ctcacgtttt 60 tcttctctga caaatgtttg aaattcagtg aaataccaaa ggagtcaagg atgaagggga 120 cacaggatgg aatcagaaaa aacataaatg gaatccaggc agttctatga gacaacactg 180 atatatctcc ttgataaaga aaaaatgtac agaatattta atgagtctgt cttgccccaa 240 aagggaaaaa cacaagtagc taagccattt gcagagagga aaaatgtcat ggaaaaatga 300 aaaatctctc ctaatgtcta tagcacatga aatatctaag taggtgggtg cagtggttca 360 tgcctggtat tgggagacca aggcaggcag atcacttgac gtcaggagtt caagaccagc 420 ctggcccaat ggngaaaccc cgtctcctat taaaaatacc aaatttagct gggcatggtg 480 gtgggtgccc tgtaacccca ncacttagga agcntaggcc gggagaatcc atgttgaccc 540 ccggaggcgg aggt 554 <210> 384 <211> 519 <212> DNA <213> HUMAN <400> 384 ttttttacat ttctcaactt ttattgtggg cccttcaacc atttttgctg ctgggtttca 60 tattttcgga ttgtttcacg gatccacagg acgtatcttg agacacgggt gtagacacca 120 ggccggtcag gttgcccaca tgggaagtct ccccaggaga gaatgccata cagtgttctg 180 ttacagacca gggggccccc agagtcaccc tcacaggagt ctttgccacc ctcttttgtg 240 ccggcacaca acatgttgtc agtgatcttt cctgggtaga cttgacgaca ctcctcatct 300 gagcgaagtt ggatgttggc acaattgtag agttttgggg taattcactc agaccttccc 360 tcccatctct gcccctgttt ccccagccac tcctatgggg cctcaggcac ctgtgtgggt 420 gcatacctgg gggctggtgg tggtgcccag ccagacaccc gacagtggtg ccaggggtta 480 ggcggttgtt gtgggaaagg ggcagggttt ggatgtagc 519 <210> 385 <211> 596 <212> DNA <213> HUMAN <400> 385 catacttaat tttttatttt gaaattccct attccctcta tacaagaacc tttgctgaaa 60 cagtttccac aaaggcagca gtgaattttc agaacattta cattttttcc ccctcagcaa 120 aaagataaat cacagtgtaa attatgttgt tctgctgtca tctttggctg gggttagacc 180 cagaagttgg tgactagcaa accaatatag ccaaatgttg ctagtgctcc ttaggccttt 240 aagctataaa ctcagcaagg aatgtctgca ttttatctct ttaaggtacc accagggggg 300 tatgacagca ttaacttcca taaactttta tagacaaatg gaaaaaaatc tacaaaattt 360 gctagtaata ttacacagca atacacactt tttatactct acacaaaacc aaaattcttg 420 gtcttaatgg cgagtaacaa tttctgtttg agaatctgtt tagaggaata gagtgggacg 480 taaagtcgag aaatgcaagt atttgcagta ggaagatgtt ggtcatctgg tggtcttatt 540 gtgattgagg gcataggctg gaatccttct tcactggctg gcagtgatgg gcttgt 596 <210> 386 <211> 358 <212> DNA <213> HUMAN <400> 386 ttcgtgcaga gccagatact ttattcatca cttgggcgat ttgaaactgc caactccgtc 60 cctccctccc ccacccttga ttctagagtg acataagaat ggtgataagt ctgaactctt 120 tcacctctta aatgccatat cattgcccac agttgccaaa tacaaaatat caagtcctct 180 gctgaagaag actgaggtcc catcgtttcc tgtgttgcag gtcacttctt caccaggtgg 240 ctgactgcat cattgtgagg cagagcatgc tgtgcaagtg tcataagtca tcccactttc 300 aactctcagg aacactcgca gccagtacca cgctgtcctc gccatccaat attgatag 358 <210> 387 <211> 457 <212> DNA <213> HUMAN <400> 387 ttttagtcat aaaaccgatt atttaattga agctataaaa aaggtagtat aagtgataaa 60 ataattagga aagaatattt agcatgtttc aaaacattta aaataggagc agaacatttt 120 acaaaaagtt gtacaggaaa ttaaattctt aaactatcag tacaaacatg acattacaga 180 gtatcttggg aagtacgggt ccggatcgga aaggactatg atgctttaag tctgaaaact 240 attggccaaa tatttaggtt tagatttaca gttcctgggt atgagaatca tattactata 300 tacatctccc aaaccagtag gtagtatttt ccaattaacc atgtgtggta tcatcttcta 360 caaagtcttt ggccatctct gctgtgatca catcaatatg actagcctta tttctggact 420 ttacaccata ggatttggca gctgactcaa gcagttc 457 <210> 388 <211> 441 <212> DNA <213> HUMAN <400> 388 cgagtctcag aaaataccag gaatgactct atccagttct gtttgtcaag taaactgttg 60 tgccagagaa acttcacttg cggagaacat ttggcaggaa caacctcatt ctaaaggtcc 120 cagtgtacct ttctccattt ttgatgagtt tcttctttca gaaaagaaga acaaaagtcc 180 tcctgcagat cccccacgag ttttagctca acgaagaccc cttgcagttc tcaaaacctc 240 agaaagcatc acctcaaatg aagatgtgtc tccagatgtt tgtgatgaat ttacaggaat 300 tgaacccttg agcgaggatg ccattatcac aggcttcaga aatgtaacaa tttgtcctaa 360 cccagaagac acttgtgact ttgccagagc agctcgtttt gcatccactc cttttcatga 420 gataatgtcc ttgaaggatc t 441 <210> 389 <211> 388 <212> DNA <213> HUMAN <400> 389 gaccagacag gattaaattt tattgaatta cagttacaag tggaaaaaat gactgactta 60 ctgcatggag aagtattatg tcaacctgtt aaaagctata gaaattaaaa tgttcatgta 120 tatacaaaat ataaatgaca tgtaaggtaa aattacagtg atcaatttac aacaaagaaa 180 ttaacagtag ttttccagct tgtttgatta atcaagcagg tttactcttg aatccatagc 240 gtttctacaa tttaatttgg acaaagttct attccagatc agccaggttt taaaactgaa 300 atgtgttaag ggtggattgt tagcttcccc aggattggtg tggatgataa atactttttt 360 taaaaattaa ttattattgt ttataaga 388 <210> 390 <211> 597 <212> DNA <213> HUMAN <400> 390 gccgacagag caagactctg tctcaaaaaa aaaaaaaaat acaattaaga ggtgtatact 60 gatgattctt cccactcatt tgtttgtcca gaagtaaata aatgtcggaa gttttccaag 120 taactatttg ttttttgggg ggttttttag ttagagtctt ggtctgtcac ccaggctgga 180 gtacagtggc aggatctcag cttgctgcag cttccatctc ccaggttcaa gcgatcatgt 240 gcctaagcct cctgagtagc tgggatcacg ggtgtgtacc accacgccca gctgattttt 300 gtatttttag taaagacttt cgccatgttg tccaggctgg tctcgaactc ctggcctaat 360 gatctgcccg cctctgcctc ccaaagtgct gggatcacag gcatgagcac cggaaccaag 420 ctttatccgc ttaaatttaa cgtgtttttt gacttcttaa ttaacttggt catataccaa 480 atgtgatctc tgtggattac cacatgcatt aaaaaatttt tcaagctggg cccagtggcg 540 cacgctgcaa tcccacactt tgggaggcca gagagggaga ttgctgagcc cagagtt 597 <210> 391 <211> 460 <212> DNA <213> HUMAN <400> 391 ccacagagta ataataaact cattcaacat tataaaaata cttttccaac tacttttaca 60 tgacttaatg tttccaatta tttgcgaaac catgtccccg caggtcttag ctggtccttg 120 tttaagattc ttaatttcat tttggcaata tctaaatttt tatttacata catgtgtact 180 aaagcattac ctatttttat ggttaaaaca tgaactttag ctgggcatgg tggctcacat 240 ctgtaatccc agcactttca gagatcaaag cgggaagact gcttgaggcc aggagatcaa 300 gaccagtctg ggcaacatag tgagacctca tcgctacaaa aaatcttaac aattagctgg 360 atgcagtggc acatgcctgt agtcccagct actcgcaggc tgaggtggga ggattccttc 420 agctcaggag ctcaaggcag cagtgagcta tgatccgtca 460 <210> 392 <211> 1817 <212> DNA <213> HUMAN <400> 392 tataaaagct tggggctggg gccgagcact ggggactttg agggtggcca ggccagcgta 60 ggatcctgct gggagcgggg aactgaggga agcgacgccg agaaagcagg cgtaccacgg 120 agggagagaa aagctccgga agcccagcag cgcctttacg cacagctgcc aactggccgc 180 tgccgaccgt ctccagctcc cgaggacgcg cgaccggaca ccgggtcctg ccacagccga 240 ggacagctcg ccgctcgccg cagcgaggcc cggggcggcc cttcaggggg acctttccca 300 gatcgcccag gccgcccgga tgtgcacgaa aatggaacag cctttctatc acgacgactc 360 ttacgcagcg gcgggatacg gtcggagccc tggcagcctg tctctacacg actacaaact 420 cctgaaaccc accttggcgc tcaacctggc ggatccctat cggggtctca agggtcctgg 480 ggcgcggggt ccaggcccgg agggcagtgg ggcaggcagc tacttttcgg gtcagggatc 540 agacacaggc gcatctctga agctagcctc cacggaactg gagcgcttga tcgtccccaa 600 cagcaacggc gtgatcacga cgacgcccac gcctccggga cagtactttt acccccgtgg 660 gggtggcagc ggtggaggta cagggggcgg cgtcaccgag gagcaggagg gctttgcgga 720 cggttttgtc aaagccctgg acgacctgca caagatgaac cacgtgacgc cccccaacgt 780 gtccctgggc gccagcgggg gtccccaggc cggcccaggg ggcgtctatg ctggtccgga 840 gccgcctccc gtctacacca acctcagcag ttactctcca gcctctgcac cctctggagg 900 ctccgggacc gccgtcggga ctgggagctc atacccgacg gccaccatca gctacctccc 960 acatgcacca ccctttgcgg gcggccaccc ggcacagctg ggtttgagtc gtggcgcttc 1020 cgcctttaaa gaggaaccgc agaccgtacc ggaggcacgc agccgcgacg ccacgccgcc 1080 tgtgtccccc atcaacatgg aagaccagga gcgcatcaaa gtggagcgaa agcggctgcg 1140 gaacaggctg gcggccacca agtgccggaa gcggaagctg gagcgcatcg cgcgcctgga 1200 ggacaaggtg aagacactca aggctgagaa cgcggggctg tcgagtgctg ccggtctcct 1260 aagggagcaa gtggcgcagc tcaagcagaa ggtcatgacc catgtcagca acggctgcca 1320 gttgctgcta ggggtcaagg gacacgcctt ctgagagcct cccttgcccc atacggacac 1380 ccccagcctt gaaggctggg cgcctgcccc ccactggggt gaggggggca ggcgatgggc 1440 acccgccaaa aggcctgggg cgcagctcac acactggact ccggcccgcc cgcctgcgcc 1500 cagtccttcc acctcgaggt ttacatggcc cccttccagc gtattttgta tgtttttttt 1560 ttctgcaaag agactgaatt catattgaat ataatatatt tgtgtattta acagggaggg 1620 gagaaggggg ctgtcgcggc ggagctggcc ccgccgcttg gtactcagcc tgcggggata 1680 ctagggaggg acctccgccc cctgccctcc ccctctgcat agtactgtgg agaagaaaca 1740 cgcacttcgt gtctaaagtc tattttaaga tgtgtttgtg tgtgtgtgtt tgacttttta 1800 ttgaatctat ttaagta 1817 <210> 393 <211> 2761 <212> DNA <213> HUMAN <400> 393 caggactggg tctcctttcc agggagagga agagcccttc atggaaccgt ctgcagcggc 60 tcagtcagtc tcggctgtcc agccagggtg tttggtggtg aggattcagg ctccgtccag 120 acaaggcagt ggcctgaggc tcagggcccc ccagcccctc cctcccagtc catcagcgtc 180 actccccagc cccgagctgg accgcacacc ttgggacacg gttttccact tcctcaggac 240 gagccccaga ctggaggaga ggtcggagga ggtgggcgtt gggctcttca cgaggacccc 300 ggcggcgggc ccgggggagg cggccgaagc ggcggcggcc gggagcgaca tggccgagga 360 acaagaccta tcagaggtgg agctgagccc tgtgggctcg gaggaacccc gctgcctgtc 420 cccaggcagc gcgccgtcgc tgggacccga cggcggcggc ggtggctcgg gcttgcgagc 480 cagcccgggg cccggtgaac tgggcaaggt caagaaggaa cagcaggacg gcgaggcgga 540 cgatgacaag ttccccgtgt gcatccgcga ggcggtcagc caggtgctca gcggctacga 600 ctggacgctg gtgcccatgc ccgtgcgcgt caacggtgcc agcaagagca agccgcacgt 660 caagaggccc atgaacgcct tcatggtgtg ggcacaggcg gcacgcagaa agctagccga 720 ccagtaccct cacctccaca atgctgagct cagcaagaca ctaggcaagc tctggaggtt 780 gctgaacgaa agtgacaagc gccccttcat tgaggaggct gagaggctcc ggatgcagca 840 caaaaaggac catccggact acaagtacca acctcggcgg cggaagaacg ggaaggcagc 900 ccagggggag gcagaatgcc caggcgggga agccgagcaa ggaggggctg ctgctattca 960 ggctcactac aagagtgccc acctggacca ccggcaccca gaagaaggct cccccatgtc 1020 agatgggaac ccagagcacc cctcaggcca gagccatggc cccccaaccc ctccaaccac 1080 cccaaagaca gagctgcagt ccggcaaggc agaccccaaa agggatgggc gctccttggg 1140 ggagggcggg aagccccaca tcgacttcgg caacgtggac atcggggaga tcagccacga 1200 ggtaatgtcc aacatggaaa cctttgatgt gactgagctg gaccaatacc tgccacccaa 1260 cgggcaccca ggccatgtgg gtagctactc ggcagctggc tacgggctgg gcagtgccct 1320 ggctgtggcc agtggacact ctgcctggat ctccaagcca ccaggtgtgg ctctgcccac 1380 ggtctcgccc cctggtgtgg atgccaaagc ccaggtgaag acagagacca caggccccca 1440 gggaccccca cactacaccg accagccgtc cacttcccag atcgcctaca cttccctcag 1500 tctgccccac tacggctccg ccttcccctc catctcacga ccccagtttg actattctga 1560 ccatcagccc tcaggaccct attatggcca tgcaggccag gcctctggcc tctattcagc 1620 cttttcttac atggggccct cccagcggcc cctctacact gccatctctg accccagccc 1680 ctcagggccc caatcccaca gtcccacaca ctgggagcag ccagtatata cgactctatc 1740 ccgaccttag aggggccctg tcaccaccag tgcccacagg gccttggggc cccttccccc 1800 agcctgtgtg ccctgctcct catcagcctc aggcttggca gtggaggagg ctgcagaggc 1860 tgacagcagc aggaaggctt ctgccagctc ctgccctgat gacctccacc caccccggct 1920 ctggaggcca agccctgact gagctggcaa aggaagtttg gtggctctcc cagactgagg 1980 gtgaggggcc acccttcccc agaaatgacc ctctatccca ggacctgaga gtcctgctca 2040 gtccttcagg gaggcaggaa gggttagggt aggaggcctc actgctcctg ttatctcctt 2100 ggagagcaag gggcccgtgt gctactgtgt cattgcctaa gagctaagct gcccagggac 2160 ctgcctcaaa gcctggagct ggttctgtcc tgtcactaag gacgcactga ggacagcttt 2220 gaacagcttt gtaaagagca gggtgggaca ctctgatcct ttctccgccc cctcttcacc 2280 tgaatgtggg aactggtcga ggtccccaga tccagttccg tgtcaataac ctcatccctt 2340 gcctaactga ggagagtccc catgttcttc ccatcccacc ccaggtgagg agccaggggc 2400 tccaggaaag agtcagaggc aatccaccta gccttcttct cgccttctgt cagcctcaag 2460 cccccaggct cagagttagc atggcacggc cctagcccct gggttgctgg cagcaggctg 2520 gacactaaac ccctgccatg tacagtctac ctttgccttg caccctttgc tccagcgata 2580 ccttaataaa gtacgtagct ctgtctcccc atctcctgtc tgcagcccag tccacatgta 2640 acacatcgct gcccctttat ttatctccat agtcgccatg ttcctatccc tctagctact 2700 ccagccccga ttaacttgca ttaagcactc caagtaataa aatcaatgct tctggtttaa 2760 a 2761 <210> 394 <211> 1466 <212> DNA <213> HUMAN <400> 394 cggccttgga tcctggaaga gaatcgctaa acacagagca gacccagtaa gtgagcaggt 60 gttttggaca atggactggt tgagcccatc tctattataa aaatgtctca gagcaaccgg 120 gagctggtgg tcgactttct ctcctacaag ctttcccaga aaggatacag ctggagtcag 180 tttagtgatg tcgaagagaa taggactgag gccccagaag aaactgaagc agagagggag 240 acccccagtg ccatcaatgg caacccatcc tggcacctgg cggatagccc ggccgtgaat 300 ggagccactg gccacagcag cagtttggat gcgcgggagg tgattcccat ggcagcagtg 360 aagcaagcgc tgagagaggc aggcgatgag tttgaactgc ggtaccggag agcgttcagt 420 gatctaacat cccagcttca cataacccca gggaccgcgt atcagagctt tgagcaggta 480 gtgaatgaac tctttcggga tggagtaaac tggggtcgca tcgtggcctt tttctccttt 540 ggcggggcac tgtgcgtgga aagcgtagac aaggagatgc aggtattggt gagtcggatt 600 gcaagttgga tggccaccta tctgaatgac cacctagagc cttggatcca ggagaacggc 660 ggctgggaca cttttgtgga tctctacggg aacaatgcag cagccgagag ccggaaaggc 720 aaggagggct tcaaccgctg gtttctgacg ggcatgactg tggctggtgt ggttctgctg 780 ggctcactct tcagtcggaa gtgaccagac actgaccgtc cactcacctc tcacctccca 840 ccctgccccc accacaactc tctcttcagc caccattgct accaggagaa ccactacatg 900 caactcacgc cccttgccct atcacagggt tgggcctaga cggagtcccc tgcaattagc 960 tttctaggat ctaccacact tctgtgaaag ccaccttccc cccacatctc agttctcttg 1020 gcctcaaaac tcacaaggtt ttcccctaaa ccagctcctt ggaggctggc aggaacagag 1080 aggggtgtgt agggaggaga gcctgtcttg ttggtgggac cctaattacc cctgagcctt 1140 ctcgggaatg cttttccagc agggagctct tcccctgaag gagactagct tgccttggtt 1200 ttgatgtgtg tggcctcaga cgtgatcatt tcccatccgc tgtgtccctg ggtctccctc 1260 ctccccatct ccacccccca agagccattg agtgaggtgc ttttagccct tttgactaat 1320 tagaaattca ggctgcttgg gataatgaga caaggaccag aacctcctcc ccacctgtgg 1380 cctggccaaa acccccactt gtggtctgaa tgttctcctg agcgctctgg ctagagtcta 1440 cgctcaccca gggggagggg cttagg 1466 <210> 395 <211> 7225 <212> DNA <213> HUMAN <400> 395 aagcttcttc ccagaacctg gaagcccagc aagcaaatgc cctgccccca cccgacctcc 60 gccctcgttg gcttcgcaaa gctgtgatct gtggccagta gagggcacac tttactttcg 120 caaatctgag agccacaacc cgggggaggg ggcggggaaa gagtctctgc agcaaaatgc 180 agcctaggga ttggtggctc ttggcgtttg aggcaaaatc ctagaggctg tagtcatttt 240 gcaatcctta aagctgaatt gtgcaatgag ctcgatgaag gaagatacta tcatccaaca 300 gctgaatcct aaattgcaaa ctcaatggct aatgactact ttgaacaatg cgcaccttac 360 acacgctaca cgctactgta gtctcttctt tttttagggg gtagcagtga gaggtttctt 420 aaaatgcctt ggggcgagga gtcctgaatg aggagactgc tttgggtttt gatgcgtagg 480 ataagcaaat cccgaggaaa tatgcactat ataataaatc tagaaccaaa acacagagca 540 aaagattcat gtttcacgtt ggttaataaa ctaggttatc gtgtatatat taagtgtgta 600 tacctttggg gactctacaa aatgcacggc atggtattga ggaaaaagta aattgggaaa 660 ttagtgtaaa aattagagtc ggcttttaat tagtttaaca cacacatacg aaggcaaaga 720 cacaacgtta ctttgatctg accggggccg accttttttt aagtgcataa ttacgattcc 780 agtaataaaa ggggaaagtt tggggtttgt cctgagagga aggggttaac ggtttccttt 840 attctagggt ctccgcaggc tccccagatc tgggttggca attctactcc tccccctttc 900 tgggaagtcc gggtttcccc caacccccaa tccatggcat attctcgcgt ctagcgcctt 960 gattcccgcc cccccacacc cccaacctct aagccggagt ctggtgcaaa ctggctccac 1020 aggggcaaag aggatttgcc tttagtggaa actggctgtg gaactggaac tctgagtgga 1080 ggtgcatggg gtgtagactg gcagagactc gaccgggagg atccgggtag agcgcgccca 1140 ccgccgcagt cctactctac tccagctctg gaacgcgcag aaagacctac ggggcaagga 1200 gccgcctcca ccccaccccg cctggtggaa ggtccgaacg ggaggtgttg gagtggaggg 1260 cctttctggc agcaaattgg gggattcatt ctgtaaagaa tgtgcccagt caacatagct 1320 gtacgcccaa acgcaaaata cacactgccc tccccgagag atgcagtggc tgtttattcc 1380 taagtggctc tccaagtata cgtggcattg agttgctgag caattttaat gattccaggc 1440 atcgtttttc tgctcagacc tcatctgtcg taggtcttca actatcactc cacactgagc 1500 aagggctcct acataactct tttttttttt cgtccttccc tttttaaatt ctgtttcccc 1560 gaccttagag agacgactgg ccgcccgaga cgtgcgtgac gcggctcagg gtacacggcg 1620 tattgtgtgg agcgaggcag ctgttccacc tgcggtgact aatacacgca ggacaagaac 1680 acagttcagc cgagcgctgc gcccgaacaa ctgtacagaa agggaaagga ccgacgcgcg 1740 agcaggagaa aatggtcggg cgcgcagtta attcatgctg cgctattact gtttacaccc 1800 cgagtcggag tactgggctg cgggactgag gctcctcctc tttccccggc tccccactag 1860 tgcccctccc gagttcccaa agcagagggc gggggagcga gaggaggaaa aaaatagagg 1920 tcgggagggg agggagaaag agattctctg gcctaatccc cgcccacccg ccctttataa 1980 tccgggggtc tgcgcggcta aggacccccg ggctgcgctg ctctccgctg ccgcctccgc 2040 cgcgcccact ccgctcgcct cctgcctcca aaagggcagg cgttcgccga ggcttggcgg 2100 gaaaaagaag cgaggggagg gatccggagt cgcagtataa aagaagcttt tcgggcgttt 2160 tttttctgac tcgctgtagt aattccagcg agagacagag ggagtgagcg ggcgggttgg 2220 aagagcccag tgtgcagagc cccactccgg gcttcctagg aaggcagctc tggagtgaga 2280 agggctttgc ctccaggctt gctgcctcct cgacccaatc ctcccgctga cccaacatca 2340 gcggtcgcaa ccctcgccgc ctctgggaaa ctttgcccat tgcaacgggc agacacttct 2400 cactggaact tacaatctgc gagccaggac aggactcccc aggcgcaggg gagggaattt 2460 ttgtctattt ggggacagtg ttctctgcct ctgcccgcga tcggctcccc tgaaaagagc 2520 tcctcgcgtt atttgaagcc tgaatttcct ttgggaggtg gaaaacccgg taagcacaga 2580 tctgttggtc ttctactgtt ttctctacgt cctgagtgta gcgaccggtt agaacagtct 2640 ttattcaatt tctgtgcttt tgacacttta ctcagagtag ttggggtagg ccggggcgga 2700 gttggggtgg atctgagtcg gggtagaacg acttgtcaag atgacaggaa aggggaagga 2760 aaaaaccggg gtgcattttg aaactgtctt ccagaggtta ccgtgggctg acgctgaccc 2820 gggccggttg gacattcttg ctgtgctaca ttaattgata tttatgtcct ttgggggggg 2880 ggtgtcaaag ccggaggtct cttcgcggtg gccaaaggaa gcccttcgta tcctgaggtc 2940 tttgggaaag ggattacctt ttgcgtgttc tccgcaaaaa gcgagaaggc tccgtagcct 3000 ctgacttccc agtctttggg agggcattta aatttcggct tggtgcattt ctgacagcct 3060 gagaccaact cgggggtgcg tcccgcccgc caatccccgg cggcgattgc aaccggtccc 3120 tgatcctttt aagaagttgc cattgggctt taaaaatagt gatcatagta aaatttaagc 3180 ctaaccctcc gcggtattag gacttggtgt tggactagcg cactgaggag aggcaaaact 3240 ggggcaggga tgtgacagat tcgttgactt ggggaaaacc agagggaatc ctcacattcc 3300 tggttgggat ccgcgggtat tccccgcgcc cctgaattgc tagggagact gcggtgagtc 3360 ttgatctgag ctgttcggta acagctgcta ccctcggcgg ggagagggaa gacgccctgc 3420 accgggtgct gaatcgctgt ggggtctctg gcgcagtggc gtcgcggttt agagtgtagc 3480 agggaggtgt ctcttattat ttgacacccc ctcccctttg gagaggcttg ttagagcctg 3540 agactgagct ctcccctcca agtcagcaat aggaaagaaa agccggcaaa ggaaggaagg 3600 ggggcgcgct gggggtggag aaagaggagg gcggagaggg gcggcggcgc cggctgggta 3660 agagccgggc gacggcgcga gtagggaccc ggacccggtc ggcggcgcaa agagccggca 3720 ccggaggggg ccgagcaccg cggcgcctct cgcctttctc cttcaggtgg cgcaaaactt 3780 tgcgcctagg cttttggcag actgtattcc ctacagtcgc ctccctcagc ctctgaagga 3840 ggccaaggcc gatggcgatt cctgggcgtc tgcagtgcta agtccctgct ctaaggaggc 3900 ggggactccg agcagctgct agtccgacca gcgtcactga tagtagggag taaaagagtg 3960 cattcccccc aaccacacac acacacacac acacacacac acacacacac acacacacac 4020 acacacttgg aagtacagca ggctgaaagg ggagtggttc aggattgggg tacgcgctgc 4080 gccaggtttc cgcatcaacc agagctgggt aactctagac ttgcttccct tgctgtgccc 4140 cctccaacag acagtcacga cgatgcccct caacgtgagc ttcgctaaca ggaactatga 4200 cctcgactac gactcggtgc agccctattt catctgcgac gaggaagaga atttctatca 4260 ccagcaacag cagagcgagc tgcagccgcc cgcacccagt gaggatatct ggaagaaatt 4320 cgagctgctg cccaccccgc ccctgtcccc cagccgccgc tccgggctct gctctccgtc 4380 ctatgtcgcg gtcgctacgt ccttctcccc aagggaggac gatgacggtg gcggtggcaa 4440 cttctccacc gccgatcagc tggagatgat gaccgagcta cttggaggag acatggtgaa 4500 tcagagcttc atctgcgatc ctgacgatga gaccttcatc aagaacatca tcatccagga 4560 ctgtatgtgg agcggcttct cggccgctgc caaactggtc tccgagaagc tggcctctta 4620 ccaggctgcg cgcaaagaca gcaccagcct gagccccgcc cgcgggcaca gcgtctgctc 4680 cacctccagc ctgtacctgc aggacctcac cgccgcagcg tccgagtgca tcgacccctc 4740 agtggtcttc ccctacccgc tcaacgacag cagctcgccc aaatcctgta cctcgtccga 4800 ttccacggcc ttctcttctt cctcggactc gctgctgtcc tccgagtcct ccccacgggc 4860 cacccctgag cccctagtgc tgcatgaaga gacaccgccc accaccagca gcgactctgg 4920 taagccgccc caaccccagc agggtaggaa gccagaggtt ggatggacct ccttctcatt 4980 ggcattaatt caattggccc ccgggctcac cctttctttc ccttcggtct aagctcttca 5040 tccctggact cctgtgcttc agatatccct ccccttcccc cagaccgccc tggttgtcag 5100 ccccaccccc acccttccca cccctcagga atttcatttg ggtttttaaa tcttctggct 5160 tatctttcaa ctcaatccac tccctttacc cctcctaggc attttaatta cccagagaag 5220 ggtgtgaagg aggataggga actgatcctg agaagagtga atgaattacc tgcttttctt 5280 tgacttcaga agaatatttg aatttaatgt ctacaagacc caagagaagc aatgacagaa 5340 gcaggacagc ctttagcctc agagccaggc actagtgaaa gatcctgaag agttgaagag 5400 ctgttttccc tccatcccgt tttgaacact tcaaagcaaa tcctcttcag tttggatttt 5460 cgtaccccct ccctccccaa atgctcgccc caccactgcc accaccagga caggacgttt 5520 ggcaaaacca caagacttta ctattgcact tccagtaata tagggagttg gtaaagtcat 5580 agcaagatat ttgcagctat cgcctacagg acctgaaggg ttcttggtga agtcccttaa 5640 aaatgggagg tgcttgggaa tgtgctttgc tttgggtgtg tctgaagcct cattaagtct 5700 taggtaagaa ttggcaacga tgccatatcc tggtacatgg taattttctc acctgtgccc 5760 taaccctgtt ctacctttct gggaaacggg aggatggtgt ctagatctgg ttcttacttc 5820 tcaatccttt ccaacttggc acttggatag catcggtcaa acccccatct gggattcagg 5880 aggcattgct aactaatctt ccacttcctt ccttacagaa gaagaacaag atgatgagga 5940 agaaattgat gtggtgtctg tggaaaagag gcaaccccct gccaagaggt ccgagtcagg 6000 gtcatcccca tcaagaggcc acagcaaacc tccacacagc ccactggtcc tcaagaggtg 6060 ccatgtctct actcaccagc acaattatgc agcacccccc tccacaagga aggactatcc 6120 agctgccaag agggccaagt tggacagtgg cagggtcctg aaacagatca gcaacaaccg 6180 caaatgctcc agccccaggt cctcagacac cgaggaaaac gacaagaggc ggacacacaa 6240 cgtcttggaa cgtcagagga gaaacgagct gaagcgtagc ttttttgccc tgcgcgacca 6300 gatccctgag ttggaaaaca acgaaaaggc ccccaaggta gttatcctca aaaaagccac 6360 cgcctacatc ctgtccgttc aagcagatga gcacaaactc atctcagaaa aggacttact 6420 gaggaaacgg cgagaacagt tgaaacacaa actcgaacag cttcgaaact ctggtgcata 6480 aactgaccgg aagtgaggag gagctggaat ctcgagtgta aggagaacgg ttccttctga 6540 cagaacttgg acttcaaaaa atgcatgctc aaagcctaac ctcacaacct tggctggggc 6600 tttgggactt cagccataat gttaactgcc tcaaagttaa ggcataaaag aacttttttt 6660 tatgcttccc atcttctttc tttttccttt aacagatttg tatttaattg ttttttttaa 6720 aaaaatcttc cggtgtacat agggccttta aatgtaaata actttaataa aacgtttata 6780 acagttatac aagattttaa gacatgtatg ataaaccata atttttttta tttaaagacc 6840 ttttcatttt taaagttgat ttttttctat tgtttttaga aaaaataaaa taattggaaa 6900 aaatataatt gagccaactc ttaaatggtg ttttcttttt tttttttcct ccaatttctc 6960 ttcctcaact atagatgaac agaactgacc gtcttcccag gacgggttta caagggtggg 7020 aaggggttat cttaaaatgg ggcgggggag gggggtgcct caagacctct aagttcccag 7080 tgttatgaga tcctttctgt ggatgctgat aggatgagag ttgagaaagg gcaaaaggca 7140 agtgaggtta gatacaagga acagggaagc aagaggttaa agatagcaga cagggaagag 7200 atggcagaat gaatctcctg cagtt 7225 <210> 396 <211> 494 <212> DNA <213> HUMAN <400> 396 cggccaccgc cgtctgggag gtgaggggcg cctctgcccg gccgccccta ctgggaagtg 60 aggagcccct ctgcccagcc accaccccgt ctgggaggtg tgcccaacag ctcattgaga 120 acgggccagg atgacaatgg cggctttgtg gaatagaaag gcgggaaagg tggggaaaag 180 attgagaaat cggatggttg ccgtgtctgt gtagaaagaa gtagacatgg gagacttttc 240 attttgttct gcactaagaa aaattcctct gccttgggat cctgttgatc tgtgacctta 300 cccccaaccc tgtgctctct gaaacatgtg ctgtgtccac tcagggttaa atggattaag 360 ggcggtgcaa gatgtgcttt gttaaacaga tgcttgaagg cagcatgctc gttaagagtc 420 atcaccactc cctaatctca agtaatcagg gacacaaaca ctgcggaagg ccgcagggtc 480 ctctgcctag gaaa 494 <210> 397 <211> 2442 <212> DNA <213> HUMAN <400> 397 cagatggctc cataatgaca gcttcataat ggcagtgggt gagcccctgg tgcacatcag 60 ggtcactctt ctgctgctct ggttggggat gtttttgtct atttctggcc actctcaggc 120 caggccctcc cagtatttca cttctccaga agtggtgatc cctttgaagg tgatcagcag 180 gggcagaggt gcaaaggctc ctggatggct ctcctatagc ctgcggtttg ggggacagag 240 atacattgtc cacatgaggg taaataagct gttgtttgct gcacaccttc ctgtgttcac 300 ctacacagag cagcatgccc tgctccagga tcagcccttc atccaggatg actggtacta 360 ccatggttat gtggaggggg tccctgagtc cttggttgcc cttagtacct gttctggggg 420 ctttcttgga atgctacaga taaatgacct tgtttatgaa atcaagccaa ttagtgtttc 480 tgccacattt gaacacctag tatataagat agacagtgat gatacacagt ttccacctat 540 gagatgtggg ttaacagaag agaaaatagc acaccagatg gagttgcaat tgtcatataa 600 tttcactctg aagcaaagtt cttttgtggg ctggtggacc catcagcggt ttgttgagct 660 ggtagtggtc gtggataata ttagatatct tttctctcaa agtaatgcaa caacagtgca 720 gcatgaagta tttaacgttg tcaatatagt ggattccttc tatcatcctt tggaggttga 780 tgtaattttg actggaattg atatatggac tgcatcaaat ccacttccta ccagtggaga 840 cctagataat gttttagagg acttttctat ttggaagaat tataacctta ataatcgact 900 acaacatgat gttgcacatc ttttcataaa agacacacaa ggcatgaagc ttggtgttgc 960 ctatgttaaa ggaatatgcc agaatccttt taatactgga gttgatgttt ttgaagacaa 1020 caggttggtc gtttttgcaa ttactttggg ccacgagctt ggtcataatt tgggtatgca 1080 acatgacacc cagtggtgtg tgtgcgagct acagtggtgc ataatgcatg cctatagaaa 1140 ggtgacaact aaatttagca actgcagtta tgcccaatat tgggacagta ctatcagtag 1200 tggattatgt attcaaccgc ctccatatcc agggaatata tttagactga agtactgtgg 1260 gaatctagtg gttgaagaag gggaggaatg tgactgtgga accatacggc agtgtgcaaa 1320 agatccctgt tgtctgttaa actgtactct acatcctggg gctgcttgtg cttttggaat 1380 atgttgcaaa gactgcaaat ttctgccatc aggaacttta tgtagacaac aagttggtga 1440 atgtgacctt ccagagtggt gcaatgggac atcccatcaa tgcccagatg atgtgtatgt 1500 gcaggacggg atctcctgta atgtgaatgc cttctgctat gaaaagacgt gtaataacca 1560 tgatatacaa tgtaaagaga tttttggcca agatgcaagg agtgcatctc agagttgcta 1620 ccaagaaatc aacacccaag gaaaccgttt cggtcactgt ggtattgtag gcacaacata 1680 tgtaaaatgt tggacccctg atatcatgtg tgggagggtt cagtgtgaaa atgtgggagt 1740 aattcccaat ctgatagagc attctacagt gcagcagttt cacctcaatg acaccacttg 1800 ctggggcact gattatcatt tagggatggc tatacctgat attggtgagg tgaaagatgg 1860 cacagtatgt ggtccagaaa agatctgcat ccgtaagaag tgtgccagta tggttcatct 1920 gtcacaagcc tgtcagcgta agacctgcaa catgagggga atctgcaaca acaaacaaca 1980 ctgtcactgc aaccatgaat gggcaccccc atactgcaag gacaaaggct atggaggtag 2040 tgctgatagt ggcccacctc ctaagaacaa catggaagga ttaaatgtga tgggaaagtt 2100 gcgttacctg tcactattgt gccttcttcc tttggttgct tttttattat tttgcttaca 2160 tgtgcttttt aagaaacgca caaaaagtaa agaagatgaa gaaggataag agaaatggga 2220 aaaagaagga gactaaactt tatacttcat ttttaatatc caatttttta atagaaaaat 2280 atgaagccat gtctcactgt ttaaataaaa cttcatggac atttcatgtc aggattgcaa 2340 gcattagcta tcacagcaaa ggattcctag cctattctta cttactttac agtgtcttaa 2400 gcaatattaa aggttccttt tcccaaaaaa aaaaaaaaaa aa 2442 <210> 398 <211> 3711 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(3711) <223> N=any base <400> 398 acagggtcgc tgagaccagt gcacgagcct cttcggaaga tgcatcctgg actcttggcc 60 gcagaagaga aagcggttgg ggtctcccag ggactctttc taaagggtca gtccaccatg 120 gtaggggtta acgtgggtcc acccgtatag ggaaaggaaa gaaattgtat ttgacacttc 180 aggggggcgg gtggcggacg ggtctcgctg cctgattggt tttgcatttc atcccaattt 240 ttttttctcc actctctctc cctcttttca gtttctctct ctgatcccag gggaggggaa 300 acgggaatag tgagagatca aaaataaacc tcttatgtca agccgggaag gaagtataaa 360 taagaagggc tcggcagccc actcggtgct tcccggggtg gggaggaggc aggaggcggc 420 tgcgcggggc tggcgcgggc aggggcggag gacgggcgca cgcgggccgg ggccagctgc 480 tcgcgctcgg ctcgggggcg gcggcgcggg aggagcgggc tgcgccagcc agaggggccg 540 ccgggggagc gctcccgccg ccgggccccg cgggcggagt cggccttgca cccgattgat 600 tccgttttcc tggagagagc ggccgggccg cgctcgggcc gccagcacct gcccgcgcct 660 ggcgggtttt tccttttcct gcgcgcagcc accgccgcag cccccatgtt ccccgccccc 720 gccgcccccc ggtggcttcc gttcctgctg ctgctgctgc tgctgctgct gccgctggcc 780 cgcggcgccc cggcccggcc cgcagccggg gggcaggcct cggagctggt ggtgcccacg 840 cggttgcccg gcagcgcggg cgagctcgcg ctccacctgt ccgccttcgg caagggcttc 900 gtgttgcgcc tggcgcccga cgacagcttc ctggcgcccg agttcaagat cgagcgcctc 960 gggggctccg gccgggcgac cgggggcgag cgggggctgc gcggctgttt tttttccggc 1020 accgtgaatg gggagcccga gtcgctggcg gcggtcagcc tgtgccgcgg gctgagcggc 1080 tccttcctgc tggacggcga ggagttcacc atccagccgc agggcgcggg gggctccctg 1140 gctcagccgc accgcctgca gcgctggggt cccgccggag cccgccccct cccgcgagga 1200 cccgagtggg aggtggagac gggagagggt cagaggcagg agagaggaga ccaccaggag 1260 gacagcgagg aggagagcca agaagaggag gcagaaggcg ctagcgagcc gccaccgccc 1320 ctgggggcca cgagtaggac caagcggttt gtgtctgagg cgcgcttcgt ggagacgctg 1380 ctggtggccg atgcgtccat ggctgccttc tacggggccg acctgcagaa ccacatcctg 1440 acgttaatgt ctgtggcagc ccgaatctac aagcacccca gcatcaagaa ttccatcaac 1500 ctgatggtgg taaaagtgct gatcgtagaa gatgaaaaat ggggcccaga ggtgtccgac 1560 aatggggggc ttacactgcg taacttctgc aactggcagc ggcgtttcaa ccagcccagc 1620 gaccgccacc cagagcacta cgacacggcc atcctgctca ccagacagaa cttctgtggg 1680 caggaggggc tgtgtgacac cctgggtgtg gcagacatcg ggaccatttg tgaccccaac 1740 aaaagctgct ccgtgatcga ggatgagggg ctccaggcgg cccacaccct ggcccatgaa 1800 ctagggcacg tcctcagcat gccccacgac gactccaagc cctgcacacg gctcttcggg 1860 cccatgggca agcaccacgt gatggcaccg ctgttcgtcc acctgaacca gacgctgccc 1920 tggtccccct gcagcgccat gtatctcaca gagcttctgg acggcgggca cggagactgt 1980 ctcctggatg cccctggtgc ggccctgccc ctccccacag gcctcccggg ccgcatggcc 2040 ctgtaccagc tggaccagca gtgcaggcag atctttgggc cggatttccg ccactgcccc 2100 aacacctctg ctcaggacgt ctgcgcccag ctttggtgcc acactgatgg ggctgagccc 2160 ctgtgccaca cgaagaatgg cagcctgccc tgggctgacg gcacgccgtg cgggcctggg 2220 cacctctgct cagaaggcag ctgtctacct gaggaggaag tggagaggcc caagcccgtg 2280 gtagatggag gctgggcacc gtggggaccc tggggagaat gttctcggac ctgtggagga 2340 ggagtacagt tttcacaccg tgagtgcaag gaccccgagc ctcagaatgg aggaagatac 2400 tgcctgggtc ggagagccaa gtaccagtca tgccacacgg aggaatgccc ccctgacggg 2460 aaaagcttca gggagcagca gtgtgagaag tataatgcct acaattacac tgacatggac 2520 gggaatctcc tgcagtgggt ccccaagtat gctggggtgt ccccccggga ccgctgcaag 2580 ttgttctgcc gagcccgggg gaggagcgag ttcaaagtgt tcgaggccaa ggtgattgat 2640 ggcaccctgt gtgggccaga aacactggcc atctgtgtcc gtggccagtg tgtcaaggcc 2700 ggctgtgacc atgtggtgga ctcgcctcgg aagctggaca aatgcggggt gtgtgggggc 2760 aaaggcaact cctgcaggaa ggtctccggg tccctcaccc ccaccaatta tggctacaat 2820 gacattgtca ccatcccagc tggtgccact aatattgacg tgaagcagcg gagccacccg 2880 ggtgtgcaga acgatgggaa ctacctggcg ctgaagacgg ctgatgggca gtacctgctc 2940 aacggcaacc tggccatctc tgccatagag caggacatct tggtgaaggg gaccatcctg 3000 aagtacagcg gctccatcgc caccctggag cgcctgcaga gcttccggcc cttgccagag 3060 cctctgacag tgcagctcct gacagtccct ggcgaggtct tccccccaaa agtcaaatac 3120 accttctttg ttcctaatga cgtggacttt agcatgcaga gcagcaaaga gagagcaacc 3180 accaacatca tccagccgct gctccacgca cagtgggtgc tgggggactg gtctgagtgc 3240 tctagcacct gcggggccgg ctggcagagg cgaactgtag agtgcaggga cccctccggc 3300 caggcctctg ccacctgcaa caaggctctg aaacccgagg atgccaagcc ctgcgaaagc 3360 cagctgtgcc ccctgtgatt caggggggca ggggccagtc ttgtgctcct ggacatgcgg 3420 tactgaggtg cagacaaggt ctccactgtg gtgactgggt cccttggcca tatcaaggca 3480 gcacggccca cccaggcctc ccattgccgc aacccctcca gtactgcaca aattcctaag 3540 ggggaagaga aaaggtatgg ggcggcaaaa cctatcatca actgtccawt gnaatggaac 3600 ttgctcgggt tcaattaaag gcataagtta aagtaaattc attatgatca acagacctca 3660 cntcatctgt tgcangatac aactantaaa aaaaaaaaaa aaaaaaaaaa a 3711 <210> 399 <211> 1936 <212> DNA <213> HUMAN <400> 399 tctggagcca agtaatggtg atactgatgc ttccttttct ttgccgcgct cggattctga 60 gtttcacaag aatgtacctg ggtgcccctt agcgggatat gaatagcttc ttcggaaccc 120 cagcggccag ctggtgcctc ctggaaagtg acgtctcatc tgcaccggac aaggaggcgg 180 ggagggagcg cagagcactc agcgtccagc agcgcggcgg gccagcctgg agcggaagcc 240 tggagtggag caggcagtcc gcgggggaca gacgtcggct gggattgagc cggcagactg 300 cgaaaagtag ctggagccgg agcagggaca gaacctgttg ctgcagacgg gcttggtgga 360 ttctggttcc tgccgccgac agggctcgcc gggagaggtt catcatgaat gagaaatggg 420 acacaaactc ttcagaaaac tggcatccca tctggaatgt caatgacaca aagcatcatc 480 tgtactcaga tattaatatt acctatgtga actactatct tcaccagcct caagtggcag 540 caatcttcat tatttcctac tttctgatct tctttttgtg catgatggga aatactgtgg 600 tttgctttat tgtaatgagg aacaaacata tgcacacagt cactaatctc ttcatcttaa 660 acctggccat aagtgattta ctagttggca tattctgcat gcctataaca ctgctggaca 720 atattatagc aggatggcca tttggaaaca cgatgtgcaa gatcagtgga ttggtccagg 780 gaatatctgt cgcagcttca gtctttacgt tagttgcaat tgctgtagat aggttccagt 840 gtgtggtcta cccttttaaa ccaaagctca ctatcaagac agcgtttgtc attattatga 900 tcatctgggt cctagccatc accattatgt ctccatctgc agtaatgtta catgtgcaag 960 aagaaaaata ttaccgagtg agactcaact cccagaataa aaccagtcca gtctactggt 1020 gccgggaaga ctggccaaat caggaaatga ggaagatcta caccactgtg ctgtttgcca 1080 acatctacct ggctcccctc tccctcattg tcatcatgta tggaaggatt ggaatttcac 1140 tcttcagggc tgcagttcct cacacaggca ggaagaacca ggagcagtgg cacgtggtgt 1200 ccaggaaaaa gcagaagatc attaagatgc tcctgattgt ggccctgctt tttattctct 1260 catggctgcc cctgtggact ctaatgatgc tctcagacta cgctgacctt tctccaaatg 1320 aactgcagat catcaacatc tacatctacc cttttgcaca ctggctggca ttcggcaaca 1380 gcagtgtcaa tcccatcatt tatggtttct tcaacgagaa tttccgccgt ggtttccaag 1440 aagctttcca gctccagctc tgccaaaaaa gagcaaagcc tatggaagct tataccctaa 1500 aagctaaaag ccatgtgctc ataaacacat ctaatcagct tgtccaggaa tctacatttc 1560 aaaaccctca tggggaaacc ttgctttata ggaaaagtgc tgaaaaaccc caacaggaat 1620 tagtgatgga agaattaaaa gaaactacta acagcagtga gatttaaaaa gagctagtgt 1680 gataatccta actctactac gcattatata tttaaatcca ttgctttttg tggctttgca 1740 cttcaaattt ttcaaagaat gttctaaata aaacatttac tgaaagccct ctctggcaaa 1800 aaaattaaaa ataaacaaaa atggtcataa gatcataaac aatcttatgt tgtataaaaa 1860 tacgtagagt gacttagaca tgtttgcatg aataaatata tttctagaga acagttaaaa 1920 aaaaaaaaaa aaaaaa 1936 <210> 400 <211> 8056 <212> DNA <213> HUMAN <400> 400 agcttgtttg gccgttttag ggtttgttgg aatttttttt tcgtctatgt acttgtgaat 60 tatttcacgt ttgccattac cggttctcca tagggtgatg ttcattagca gtggtgatag 120 gttaattttc accatctctt atgcggttga atagtcacct ctgaaccact ttttcctcca 180 gtaactcctc tttcttcgga ccttctgcag ccaacctgaa agaataacaa ggaggtggct 240 ggaaacttgt tttaaggaac cgcctgtcct tcccccgctg gaaaccttgc acctcggacg 300 ctcctgctcc tgcccccacc tgacccccgc cctcgttgac atccaggcgc gatgatctct 360 gctgccagta gagggcacac ttactttact ttcgcaaacc tgaacgcggg tgctgcccag 420 agagggggcg gagggaaaga cgctttgcag caaaatccag catagcgatt ggttgctccc 480 cgcgtttgcg gcaaaggcct ggaggcagga gtaatttgca atccttaaag ctgaattgtg 540 cagtgcatcg gatttggaag ctactatatt cacttaacac ttgaacgctg agctgcaaac 600 tcaacgggta ataacccatc ttgaacagcg tacatgctat acacgcaccc ctttcccccg 660 aattgttttc tcttttggag gtggtggagg gagagaaaag tttacttaaa atgcctttgg 720 gtgagggacc aaggatgaga agaatgtttt ttgtttttca tgccgtggaa taacacaaaa 780 taaaaaatcc cgagggaata tacattatat attaaatata gatcatttca gggagcaaac 840 aaatcatgtg tggggctggg caactagcta agtcgaagcg taaataaaat gtgaatacac 900 gtttgcgggt tacatacagt gcactttcac tagtattcag aaaaaattgt gagtcagtga 960 actaggaaat taatgcctgg aaggcagcca aattttaatt aactcaagac tccccccccc 1020 ccaaaaaaag gcacggaagt aatactcctc tcctcttctt tgatcagaat cgatgcattt 1080 tttgtgcatg accgcatttc caataataaa aggggaaaga ggacctggaa aggaattaaa 1140 cgtccggttt gtccggggag gaaagagtta acggtttttt tcacaagggt ctctgctgac 1200 tcccccggct cggtccacaa gctctccact tgcccctttt aggaagtccg gtcccgcggt 1260 tcgggtaccc cctgcccctc ccatattctc ccgtctagca cctttgattt ctcccaaacc 1320 cggcagcccg agactgttgc aaaccggcgc cacagggcgc aaaggggatt tgtctcttct 1380 gaaacctggc tgagaaattg ggaactccgt gtgggaggcg tgggggtggg acggtggggt 1440 acagactggc agagagcagg caacctccct ctcgccctag tccagctctg gaacaggcag 1500 acacatctca gggctaaaca gacgcctccc gcacggggcc ccacggaagc ctgagcaggc 1560 ggggcaggag gggcggtatc tgctgctttg gcagcaaatt gggggactca gtctgggtgg 1620 aaggtatcca atccagatag ctgtgcatac ataatgcata atacatgact ccccccaaca 1680 aatgcaatgg gagtttattc ataacgcgct ctccaagtat acgtggcaat gcgttgctgg 1740 gttattttaa tcattctagg catcgttttc ctccttatgc ctctatcatt cctccctatc 1800 tacactaaca tcccacgctc tgaacgcgcg cccattaata cccttctttc ctccactctc 1860 cctgggactc ttgatcaaag cgcggccctt tccccagcct tagcgaggcg ccctgcagcc 1920 tggtacgcgc gtggcgtggc ggtgggcgcg cagtgcgttc tcggtgtgga gggcagctgt 1980 tccgcctgcg atgatttata ctcacaggac aaggatgcgg tttgtcaaac aatactgcta 2040 cggaggagca gcagagaaag ggagagggtt tgagagggag caaaagaaaa tggtaggcgc 2100 gcgtagttaa ttcatgcggc tctcttactc tgtttacatc ctagagctag agtgctcggc 2160 tgcccggctg agtctcctcc ccaccttccc caccctcccc accctcccca taagcgcccc 2220 tcccgggttc ccaaagcaga gggcgtgggg gaaaagaaaa aagatcctct ctcgctaatc 2280 tccgcccacc ggccctttat aatgcgaggg tctggacggc tgaggacccc cgagctgtgc 2340 tgctcgcggc cgccaccgcc gggccccggc cgtccctggc tcccctcctg cctcgagaag 2400 ggcagggctt ctcagaggct tggcgggaaa aagaacggag ggagggatcg cgctgagtat 2460 aaaagccggt tttcggggct ttatctaact cgctgtagta attccagtga gaggcagagg 2520 gagcgagcgg gcggccggct agggtggaag agccgggcga gcagagctgc gctgcgggcg 2580 tcctgggaag ggagatccgg agcgaatagg gggcttcgcc tctggcccag acctcccgct 2640 gatcccccag gcagcggtcc gcaacccttg ccgcatccac gaaactttgc ccatagcagc 2700 gggcggacac tttgcactgg aactgacaac acccgaccaa ggacgcgact ctcccgacgc 2760 ggggaggcta ttctgcccat ttggggacac ttccccgccg ctgccaggac ccgcttctct 2820 gaaaggctct ccttgcagct gcttagatac tgaatttttt tcgggaagtg gaaaaccagg 2880 taagcatcga agtccacttg tcttttaatt tactttttta tcagtttaat tctgagatga 2940 gtcgaatgcc taaatagggt gtcttttctc ccaatcctgc gttattgaca cctttctcgg 3000 ggtgggggtt attccagaat tggatcgggg tacagtgact tgtcaagatg ggggaggaga 3060 agacagaggg aaaacgggaa tggtttttac gattatcctt tcgagatttc tgccttatga 3120 atatattcac gtcgactccc ggccggtcgg acattcctac tttattgtgt taattgttct 3180 ctgggttttg gggggcgggg ggttgctttg cggtgggcag aaagtccctt gcatcttgag 3240 ctccttggag aagggaccgc atatcgcctg tgtgagccag atcgctccgc aggcgctgac 3300 ttgtccccgt ctccgggagg gcagttaaat ctcgactcac cgcatttctg acagccggag 3360 acggacactg cggcgcgtcc cgcccgcctg tccccgcggc gattccaacc cgccctgatt 3420 cttttaagaa gttgacattt ggctttttaa aaagcaataa aacaatttaa aacctgggtc 3480 tctagaagtg ttaggacgtg gtgttgggta ggcgcaggca ggggaaaagg gaggcgagga 3540 tgtgtccgat tctcctgcaa tcgttgactt ggaaaaacca gggcgaatct ccgcacccag 3600 tcctgactcc cctgccgcgg ccgccctcgg gtgtcctcgc gcccgagatg cggaggaact 3660 gcgaggagcg gggctctggg cggttccaaa acagctgcta cccttggtgg ggtggctccg 3720 ggggaggtat cgcagcgggg tctctggcgc agttgcatct ccgtattgag tgcgaaggga 3780 ggtgccccta ttattatttg acacccccct tgtatttatg gaggggtgtt aaagtccgcg 3840 gctgagctcg ccactccagc cggcgagaga aagaagaaaa gctggcaaaa ggagtgttgg 3900 acgggggcag tactgggggt ggggacgggg gcggtggaga gggaaggttg ggaggggctg 3960 cggtgccggc gggggtagga gagcgcctag ggcgcgagtg ggaacagccg cagcggaggg 4020 gccccggcgc ggagcggggt tcacgcagcc gctttcgccc aggcgccttt cgccttctcc 4080 ttcaggtggc gcaaaacttt gtgccttgga ttttggcaaa ttgtattcct caccgccacc 4140 tcccgcggct tcttaagggc gccagggccg atttcgattc ctctgccgct gcggggccga 4200 ctcccgggct ttgcgctccg ggctcccggg ggagcggggg ctcggcgggt accaagacgc 4260 tggttcacta agtgcgtctc cgagatagca ggggactgtc caaagggggt gaaagggtgc 4320 tccctttatt cccccaccaa gaccacccag ccgctttagg ggatagctct gcaaggggag 4380 aggttcggga ctgtggcgcg cactgcgcgc tgcgccaggt ttccgcacca agaccccttt 4440 aactcaagac tgcctcccgc tttgtgtgcc ccgctccagc agcctcccgc gacgatgccc 4500 ctcaacgtta gcttcaccaa caggaactat gacctcgact acgactcggt gcagccgtat 4560 ttctactgcg acgaggagga gaacttctac cagcagcagc agcagagcga actgcagccc 4620 ccggcgccca gcgaggatat ctggaagaaa ttcgagctgc tgcccacccc gcccctgtcc 4680 cctagccgcc gctccgggct ctgctcgccc tcctacgttg cggtcacacc cttctccctt 4740 cggggagaca acgacggcgg tggcgggagc ttctccacgg ccgaccagct ggagatggtg 4800 accgagctgc tgggaggaga catggtgaac cagagtttca tctgcgaccc ggacgacgag 4860 accttcatca aaaacatcat catccaggac tgtatgtgga gcggcttctc ggccgccgcc 4920 aagctcgtct cagagaagct ggcctcctac caggctgcgc gcaaagacag cggcagcccg 4980 aaccccgccc gcggccacag cgtctgctcc acctccagct tgtacctgca ggatctgagc 5040 gccgccgcct cagagtgcat cgacccctcg gtggtcttcc cctaccctct caacgacagc 5100 agctcgccca agtcctgcgc ctcgcaagac tccagcgcct tctctccgtc ctcggattct 5160 ctgctctcct cgacggagtc ctccccgcag ggcagccccg agcccctggt gctccatgag 5220 gagacaccgc ccaccaccag cagcgactct ggtaagcgaa gcccgcccag gcctgtcaaa 5280 agtgggcggc tggatacctt tcccattttc attggcagct tatttaacgg gccactctta 5340 ttaggaagga gagatagcag atctggagag atttgggagc tcatcacctc tgaaaccttg 5400 ggctttagcg tttcctccca tcccttcccc ttagactgcc catgtttgca gcccccctcc 5460 ccgtttgtct cccacccctc aggaatttca tttaggtttt taaaccttct ggcttatctt 5520 acaactcaat ccacttcttc ttacctcccg ttaacatttt aattgccctg gggcggggtg 5580 gcagggagtg tatgaatgag gataagagag gattgatctc tgagagtgaa tgaattgctt 5640 ccctcttaac ttccgagaag tggtgggatt taatgaacta tctacaaaaa tgaggggctg 5700 tgtttagagg ctaggcaggg cctgcctgag tgcgggagcc agtgaactgc ctcaagagtg 5760 ggtgggctga ggagctggga tcttctcagc ctattttgaa cactgaaaag caaatccttg 5820 ccaaagttgg actttttttt tcttttattc cttcccccgc cctcttggac ttttggcaaa 5880 actgcaattt tttttttttt tatttttcat ttccagtaaa atagggagtt gctaaagtca 5940 taccaagcaa tttgcagcta tcatttgcaa cacctgaagt gttcttggta aagtccctca 6000 aaaataggag gtgcttggga atgtgctttg ctttgggtgt gtccaaagcc tcattaagtc 6060 ttaggtaaga attggcatca atgtcctatc ctgggaagtt gcacttttct tgtccatgcc 6120 ataacccagc tgtctttccc tttatgagac tcttaccttc atggtgagag gagtaagggt 6180 ggctggctag attggttctt tttttttttt tttccttttt taagacggag tctcactctg 6240 tcactaggct ggagtgcagt ggcgcaatca acctccaacc ccctggttca agagattctc 6300 ctgcctcagc ctcccaagta gctgggacta caggtgcaca ccaccatgcc aggctaattt 6360 ttgtaatttt agtagagatg gggtttcatc gtgttggcca ggatggtctc tcctgacctc 6420 acgatccgcc cacctcggcc tcccaaagtg ctgggattac aggtgtgagc cagggcacca 6480 ggcttagatg tggctctttg gggagataat tttgtccaga gacctttcta acgtattcat 6540 gccttgtatt tgtacagcat taatctggta attgattatt ttaatgtaac cttgctaaag 6600 gagtgatttc tatttccttt cttaaagagg aggaacaaga agatgaggaa gaaatcgatg 6660 ttgtttctgt ggaaaagagg caggctcctg gcaaaaggtc agagtctgga tcaccttctg 6720 ctggaggcca cagcaaacct cctcacagcc cactggtcct caagaggtgc cacgtctcca 6780 cacatcagca caactacgca gcgcctccct ccactcggaa ggactatcct gctgccaaga 6840 gggtcaagtt ggacagtgtc agagtcctga gacagatcag caacaaccga aaatgcacca 6900 gccccaggtc ctcggacacc gaggagaatg tcaagaggcg aacacacaac gtcttggagc 6960 gccagaggag gaacgagcta aaacggagct tttttgccct gcgtgaccag atcccggagt 7020 tggaaaacaa tgaaaaggcc cccaaggtag ttatccttaa aaaagccaca gcatacatcc 7080 tgtccgtcca agcagaggag caaaagctca tttctgaaga ggacttgttg cggaaacgac 7140 gagaacagtt gaaacacaaa cttgaacagc tacggaactc ttgtgcgtaa ggaaaagtaa 7200 ggaaaacgat tccttctaac agaaatgtcc tgagcaatcg cctatgaact tgtttcaaat 7260 gcatgatcaa atgcaacctc acaaccttgg ctgagtcttg agactgaaag atttagccat 7320 aatgtaaact gcctcaaatt ggactttggg cataaaagaa cttttttatg cttaccatct 7380 tttttttttc tttaacagat ttgtatttaa gaattgtttt taaaaaattt taagatttac 7440 acaatgtttc tctgtaaata ttgccattaa atgtaaataa ctttaataaa acgtttatag 7500 cagttacaca gaatttcaat cctagtatat agtacctagt attataggta ctataaaccc 7560 taattttttt tatttaagta cattttgctt tttaaagttg atttttttct attgttttta 7620 gaaaaaataa aataactggc aaatatatca ttgagccaaa tcttaagttg tgaatgtttt 7680 gtttcgtttc ttccccctcc caaccaccac catccctgtt tgttttcatc aattgcccct 7740 tcagagggtg gtcttaagaa aggcaagagt tttcctctgt tgaaatgggt ctgggggcct 7800 taaggtcttt aagttcttgg aggttctaag atgcttcctg gagactatga taacagccag 7860 agttgacagt tagaaggaat ggcagaaggc aggtgagaag gtgagaggta ggcaaaggag 7920 atacaagagg tcaaaggtag cagttaagta cacaaagagg cataaggact ggggagttgg 7980 gaggaaggtg aggaagaaac tcctgttact ttagttaacc agtgccagtc ccctgctcac 8040 tccaaaccca ggaatt 8056 <210> 401 <211> 1487 <212> DNA <213> HUMAN <400> 401 ctagcactct gacctagcag tcaacatgaa ggctctcatt gttctggggc ttgtcctcct 60 ttctgttacg gtccagggca aggtctttga aaggtgtgag ttggccagaa ctctgaaaag 120 attgggaatg gatggctaca ggggaatcag cctagcaaac tggatgtgtt tggccaaatg 180 ggagagtggt tacaacacac gagctacaaa ctacaatgct ggagacagaa gcactgatta 240 tgggatattt cagatcaata gccgctactg gtgtaatgat ggcaaaaccc caggagcagt 300 taatgcctgt catttatcct gcagtgcttt gctgcaagat aacatcgctg atgctgtagc 360 ttgtgcaaag agggttgtcc gtgatccaca aggcattaga gcatgggtgg catggagaaa 420 tcgttgtcaa aacagagatg tccgtcagta tgttcaaggt tgtggagtgt aactccagaa 480 ttttccttct tcagctcatt ttgtctctct cacattaagg gagtaggaat taagtgaaag 540 gtcacactac cattatttcc ccttcaaaca aataatattt ttacagaagc aggagcaaaa 600 tatggccttt cttctaagag atataatgtt cactaatgtg gttattttac attaagccta 660 caacattttt cagtttgcaa atagaactaa tactggtgaa aatttaccta aaaccttggt 720 tatcaaatac atctccagta cattccgttc tttttttttt ttgagacagt ctcgctctgt 780 cgcccaggct ggagtgcagt ggcgcaatct cggctcactg caacctccac ctcccgggtt 840 cacgccattc tcctgcctca gcctcccgag tagctgggat tacgggcgcc cgccaccacg 900 cccggctaat tttttgtatt tttagtagag acagggtttc accgtgttag ccaggatggt 960 ctcgatctcc tgaccttgtg atccacccac ctcggcctcc caaagtgctg ggattacagg 1020 cgtgagccac tgcgcccggc cacattcagt tcttatcaaa gaaataaccc agacttaatc 1080 ttgaatgata cgattatgcc caatattaag taaaaaatat aagaaaaggt tatcttaaat 1140 agatcttagg caaaatacca gctgatgaag gcatctgatg ccttcatctg ttcagtcatc 1200 tccaaaaaca gtaaaaataa ccactttttg ttgggcaata tgaaattttt aaaggagtag 1260 aataccaaat gatagaaaca gactgcctga attgagaatt ttgatttctt aaagtgtgtt 1320 tctttctaaa ttgctgttcc ttaatttgat taatttaatt catgtattat gattaaatct 1380 gaggcagatg agcttacaag tattgaaata attactaatt aatcacaaat gtgaagttat 1440 gcatgatgta aaaaatacaa acattctaat taaaggcttt gcaacac 1487 <210> 402 <211> 1541 <212> DNA <213> HUMAN <400> 402 gttgtgctgt cagtgcacca gagacacaag gcttgaagct ctgtcctggg aaaatatggc 60 aaacagtgcc tctcctgaac agaatcaaaa tcactgttca gccatcaaca acagcatccc 120 actgatgcag ggcaacctcc ccactctgac cttgtctgga aagatccgag tgacggttac 180 tttcttcctt tttctgctct ctgcgacctt taatgcttct ttcttgttga aacttcagaa 240 gtggacacag aagaaagaga aagggaaaaa gctctcaaga atgaagctgc tcttaaaaca 300 tctgacctta gccaacctgt tggagactct gattgtcatg ccactggatg ggatgtggaa 360 cattacagtc caatggtatg ctggagagtt actctgcaaa gttctcagtt atctaaagct 420 tttctccatg tatgccccag ccttcatgat ggtggtgatc agcctggacc gctccctggc 480 tatcacgagg cccctagctt tgaaaagcaa cagcaaagtc ggacagtcca tggttggcct 540 ggcctggatc ctcagtagtg tctttgcagg accacagtta tacatcttca ggatgattca 600 tctagcagac agctctggac agacaaaagt tttctctcaa tgtgtaacac actgcagttt 660 ttcacaatgg tggcatcaag cattttataa ctttttcacc ttcagctgcc tcttcatcat 720 ccctcttttc atcatgctga tctgcaatgc aaaaatcatc ttcaccctga cacgggtcct 780 tcatcaggac ccccacgaac tacaactgaa tcagtccaag aacaatatac caagagcacg 840 gctgaagact ctaaaaatga cggttgcatt tgccacttca tttactgtct gctggactcc 900 ctactatgtc ctaggaattt ggtattggtt tgatcctgaa atgttaaaca ggttgtcaga 960 cccagtaaat cacttcttct ttctctttgc ctttttaaac ccatgctttg atccacttat 1020 ctatggatat ttttctctgt gattgataga ctacacaaga agtcatatga agaagggtaa 1080 ggtaatgaat ctctccatct gggaatgatt aacacaaatg ttggagcatg tttacataca 1140 aacaaagtag gatttacact taagttatca ttcttttaga aactcagtct tcagagcctc 1200 aattattaag gaaaagctct tcaggaaaaa tactaaaata tttctcttcc tcataagctt 1260 ctaaattaat ctctgccttt tctgacctca tataacacat tatgtaggtt tcttatcact 1320 ttctctttgc ataataatgt actaatattt aaaatacctt cagcctaagg cacaaggatg 1380 ccaaaaaaac aaaggtgaga aaccacaaca caggtctaaa ctcagcatgc tttggtgagt 1440 ttttctccaa aaggggcata ttagcaatta gagttgtatg ctatataata catagagcac 1500 agagcccttt gcccataata tcaactttcc ctcctatagt t 1541 <210> 403 <211> 1547 <212> DNA <213> HUMAN <400> 403 ggggacttct tgaacttgca gggagaataa cttgcgcacc ccactttgcg ccggtgcctt 60 tgccccagcg gagcctgctt cgccatctcc gagccccacc gcccctccac tcctcggcct 120 tgcccgacac tgagacgctg ttcccagcgt gaaaagagag actgcgcggc cggcacccgg 180 gagaaggagg aggcaaagaa aaggaacgga cattcggtcc ttgcgccagg tcctttgacc 240 agagtttttc catgtggacg ctctttcaat ggacgtgtcc ccgcgtgctt cttagacgga 300 ctgcggtctc ctaaaggtcg accatggtgg ccgggacccg ctgtcttcta gcgttgctgc 360 ttccccaggt cctcctgggc ggcgcggctg gcctcgttcc ggagctgggc cgcaggaagt 420 tcgcggcggc gtcgtcgggc cgcccctcat cccagccctc tgacgaggtc ctgagcgagt 480 tcgagttgcg gctgctcagc atgttcggcc tgaaacagag acccaccccc agcagggacg 540 ccgtggtgcc cccctacatg ctagacctgt atcgcaggca ctcaggtcag ccgggctcac 600 ccgccccaga ccaccggttg gagagggcag ccagccgagc caacactgtg cgcagcttcc 660 accatgaaga atctttggaa gaactaccag aaacgagtgg gaaaacaacc cggagattct 720 tctttaattt aagttctatc cccacggagg agtttatcac ctcagcagag cttcaggttt 780 tccgagaaca gatgcaagat gctttaggaa acaatagcag tttccatcac cgaattaata 840 tttatgaaat cataaaacct gcaacagcca actcgaaatt ccccgtgacc agacttttgg 900 acaccaggtt ggtgaatcag aatgcaagca ggtgggaaag ttttgatgtc acccccgctg 960 tgatgcggtg gactgcacag ggacacgcca accatggatt cgtggtggaa gtggcccact 1020 tggaggagaa acaaggtgtc tccaagagac atgttaggat aagcaggtct ttgcaccaag 1080 atgaacacag ctggtcacag ataaggccat tgctagtaac ttttggccat gatggaaaag 1140 ggcatcctct ccacaaaaga gaaaaacgtc aagccaaaca caaacagcgg aaacgcctta 1200 agtccagctg taagagacac cctttgtacg tggacttcag tgacgtgggg tggaatgact 1260 ggattgtggc tcccccgggg tatcacgcct tttactgcca cggagaatgc ccttttcctc 1320 tggctgatca tctgaactcc actaatcatg ccattgttca gacgttggtc aactctgtta 1380 actctaagat tcctaaggca tgctgtgtcc cgacagaact cagtgctatc tcgatgctgt 1440 accttgacga gaatgaaaag gttgtattaa agaactatca ggacatggtt gtggagggtt 1500 gtgggtgtcg ctagtacagc aaaattaaat acataaatat atatata 1547 <210> 404 <211> 4341 <212> DNA <213> HUMAN <400> 404 gaattccgga cccggtagga gggggcgggg ccgggggaga aggcgccgcc tccgcccctt 60 cgggacccgg agggtgccct tgtttacctc ccagtatttg tcacccgaga caaagaggga 120 aggaaggagg agccttctga gggaaactcc ctcggcggga agcatcttac tttcagaacg 180 ttttttaaca ccctacggac gcgggaacgg ttccctcccg gccccccgcg ccctttccga 240 ggttccctgc cttgacttcc ccgagttcta cgacaacctc agcgacagcg ggaggagctg 300 ggcaatcggt tttgcagggc aaactccagg ctctcctcat ttattattct ctgggcggcg 360 cacgggagac cctgcagggc aacagagcag agcgactaca gctcccagga gccaacgctg 420 cagggctgag ccgacgcggg ggacagacag gacctaaatg gtggtcggag gaagggcaag 480 gcagacctct tctgttacct tagcgccagc aaaccgagcc gccgccgtcg ccaagccagg 540 agaccaaccc ccagtctccc gactaagtat ttttaaatct ggcggggctt tccttcccga 600 gccaaccact cccaccgttt acagccccaa ccagtcagcg tgaggcccgc catttttcaa 660 accctcttcc cgccgccaat caggatcgag cagtacattc ctctcctgac cggttctaac 720 gggtctggga gttaacgacc tgggcgaccc accgaacctg ctaggctggg gcgtggaggg 780 cgggtctggt aagacactga ccaatcgtta gcctccgtgg caagggggcg gggactatct 840 gggtttgaat aatcgtcaga accaatcaga ttagtgggga tgtggcccgt ggcctagctc 900 gtcaagttgc cgtggcgcgg agaactctgc aaaacaagag gctgaggatt gcgttagaga 960 taaaccagtt cacgccggag ccccgtgagg gaagcgtctc cgttgggtcc ggccgctctg 1020 cgggactctg aggaaaagct cgcaccaggc aagaataccc tccaataccc tcgggttcgt 1080 ggacctgcct ttccccattc cctcagagcc tctactcggt ctcggcgcag tggctctcgg 1140 ggtctgaccc ggcgagcggc atttggggtg cgggccggcg agggctgggt ctgtggaggg 1200 ccggcgggca gtcggaggag gcggaaactg cccctgaccg ggcccggttc tgggagtttt 1260 caatgtcggt cacgaggtgc ttagcggtta agtgaggctc gcgacgtggg agctggggga 1320 catttctgtc aggaaaggcg ttttgagggc gcttgcggag tcaccggact cggtgaaggg 1380 tgggcggcgg cgtctcgggc cccgggagcc acttgctggg ctgagccgcg gccgctcggg 1440 ccgggaggag gaggaggagg agggtgtgcg ccggggcgcg ggcgggggcg cggcggccgc 1500 ccttgggagg acgccctcgg gaggaggggg gcgcgggcag ggcgggagcg gatttgggcg 1560 ggaagcggag ccccgccagc gcccgccctg gcagctgcgg cgtccgcgcc gacctccggc 1620 ttcccctctc ccccctcggc cccgtcaggt ggacgcggat ctgtcaacat gggtaaagga 1680 gaccccaaca agccgcgggg caaaatgtcc tcgtacgcct tcttcgtgca gacctgccgg 1740 gaagagcaca agaagaaaca cccggactct tccgtcaatt tcgcggaatt ctccaagaag 1800 tgttcggaga gatggaaggt gaggcaggag agggacggag ctcagggggt gcaggtgtgg 1860 ttttcggcta ggagggcctt aggcaggtag taggcaactc atgagcttca actttgccac 1920 cccagtgact cacctgaata tcttaagagt tccaggcaga cgattttagg tttttactta 1980 tataagactt cgaaagcaaa atgctgttaa ggaaaatgtg gtccttaaag atgatcttgt 2040 cgtctttgga tgtttatagg taacaatttt gctgtatttt tggctcttat tttatgtcca 2100 cagaccatgt ctgcaaagga gaagtcgaag tttgaagata tggcaaaaag tgacaaagct 2160 cgctatgaca gggagatgaa aaattacgtt cctcccaaag gtgataagaa ggggaagaaa 2220 aaggacccca atgctcctaa aaggccaccg taagtttaaa ataacccaaa ttgctccttg 2280 gatttttcct tcagtttatt aaactctgtt gcttcctttc agatctgcct tcttcctgtt 2340 ttgctctgaa catcgcccaa agatcaaaag tgaacaccct ggcctatcca ttggggatac 2400 tgcaaagaaa ttgggtgaaa tgtggtctga gcagtcagcc aaagataaac aaccatatga 2460 acagaaagca gctaagctaa aggagaaata tgaaaaggta cagtgtcatc ttttttaaag 2520 ccgtggataa gactaggtat aggtaataac tgtagaaaac ctgggaaatt tagttaatct 2580 tgtattaatg gttgtcagct atgttttgaa aaggcctaat gaaaattgta cacttcaaca 2640 caaggtaatt gaaaccttcc ttttgactga aaccagtgtt tgtagcacta gtatattcct 2700 gcagacagac ttgtagttac ttgtagttat tgtatagtct gtatagtctg ttattttttt 2760 ttttaagcag agagtcaaag aaattgtttt atgtagatat atataaaatg tgaaggtaca 2820 ggagggacta tggcactgtg tgtgatgtaa aagggtattg gtagtgaaag tactgatact 2880 gctgtatcgc aacccttgtc attttacgtc attaacttgt taaagcctag tgggataagt 2940 gctctaaaaa cttagactgg ttaccttttt agacagttat tagggttatt ggtcaatcat 3000 cttagattgt ttacaactaa gtggtttttc acagttgagt aatgataccg gatgctttat 3060 ttttttgaca atatttcagg atattgctgc atatcgtgcc aagggcaaaa gtgaagcagg 3120 aaagaagggc cctggcaggc caacaggctc aaagaagaag aacgaaccag aagatgagga 3180 ggaggaggag gaagaagaag atgaagatga ggaggaagag gatgaagatg aagaataaat 3240 ggctatcctt taatgatgcg tgtggaatgt gtgtgtgtgc tcaggcaatt attttgctaa 3300 gaatgtgaat tcaagtgcag ctcaatacta gcttcagtat aaaaactgta cagatttttg 3360 tatagctgat aagattctct gtagagaaaa tacttttaaa aaatgcaggt tgtagctttt 3420 tgatgggcta ctcatacagt tagattttac agcttctgat gttgaatgtt cctaaatatt 3480 taatggtttt tttaatttct tgtgtatggt agcacagcaa acttgtagga attagtatca 3540 atagtaaatt ttgggttttt taggatgttg catttcgttt ttttaaaaaa aattttgtaa 3600 taaaattatg tatattattt ctattgtctt tgtcttaata tgctaagtta attttcactt 3660 taaaaaagcc atttgaagac cagagctatg ttgatttttt tcggtatttc tgcctagtag 3720 tagttcttag acacagttga cctagtaaaa tgtttgagaa ttaaaaccaa acatgctcat 3780 atttgcaaaa tgttctttaa aagttacatg ttgaactcag tgaactttat aagaatttat 3840 gcagttttac agaacgttaa gttttgtact tgacgtttct gtttattagc taaattgttc 3900 ctcaggtgtg tgtatatata tatacatata tatatatata tatatgtata tatatacaca 3960 tatatacgta tatatacata tatatgtata tggagtctca ctctgttgcc caggctggag 4020 tgcagtggca cgatcccagc tcactgcaac ctccgcctcc cgggttcaag cgattcttct 4080 gcctcagcct ccctggtagc tggggctaca gccatgtgcc accaagccca gctaatttat 4140 atttttagta gagacagggt ttcaccatgt tggtgaggct ggtctggaac tgacctcaaa 4200 tgatctgccc acctcagcct cccaaagtgt tgggattaac aggtgtgagc caccacgcct 4260 gtcccagtat attgtttaac aagtttattt tgggtgaaaa attctcttta atgggaagaa 4320 gaggggctag aatgtgaatt c 4341 <210> 405 <211> 503 <212> DNA <213> HUMAN <400> 405 gacagcggct tccttgatcc ttgccacccg cgactgaaca ccgacagcag cagcctcacc 60 atgaagttgc tgatggtcct catgctggcg gccctctccc agcactgcta cgcaggctct 120 ggctgcccct tattggagaa tgtgatttcc aagacaatca atccacaagt gtctaagact 180 gaatacaaag aacttcttca agagttcata gacgacaatg ccactacaaa tgccatagat 240 gaattgaagg aatgttttct taaccaaacg gatgaaactc tgagcaatgt tgaggtgttt 300 atgcaattaa tatatgacag cagtctttgt gatttatttt aactttctgc aagacctttg 360 gctcacagaa ctgcagggta tggtgagaaa ccaactacgg attgctgcaa accacacctt 420 ctctttctta tgtcttttta ctacaaacta caagacaatt gttgaaacct gctatacatg 480 tttattttaa taaattgatg gca 503 <210> 406 <211> 1694 <212> DNA <213> HUMAN <400> 406 gggccggctc gcgggcgctg ccagtctcgg gcggcggtgt ccggcgcgcg ggcggcctgc 60 tgggcgggct gaagggttag cggagcacgg gcaaggcgga gagtgacgga gtcggcgagc 120 ccccgcggcg acaggttctc tacttaaaag acaatgacta ctgatgaagg tgccaagaac 180 aatgaagaaa gccccacagc cactgttgct gagcagggag aggatattac ctccaaaaaa 240 gacaggggag tattaaagat tgtcaaaaga gtggggaatg gtgaggaaac gccgatgatt 300 ggagacaaag tttatgtcca ttacaaagga aaattgtcaa atggaaagaa gtttgattcc 360 agtcatgata gaaatgaacc atttgtcttt agtcttggca aaggccaagt catcaaggca 420 tgggacattg gggtggctac catgaagaaa ggagagatat gccatttact gtgcaaacca 480 gaatatgcat atggctcggc tggcagtctc cctaaaattc cctcgaatgc aactctcttt 540 tttgagattg agctccttga tttcaaagga gaggatttat ttgaagatgg aggcattatc 600 cggagaacca aacggaaagg agagggatat tcaaatccaa acgaaggagc aacagtagaa 660 atccacctgg aaggccgctg tggtggaagg atgtttgact gcagagatgt ggcattcact 720 gtgggcgaag gagaagacca cgacattcca attggaattg acaaagctct ggagaaaatg 780 cagcgggaag aacaatgtat tttatatctt ggaccaagat atggttttgg agaggcaggg 840 aagcctaaat ttggcattga acctaatgct gagcttatat atgaagttac acttaagagc 900 ttcgaaaagg ccaaagaatc ctgggagatg gataccaaag aaaaattgga gcaggctgcc 960 attgtcaaag agaagggaac cgtatacttc aagggaggca aatacatgca ggcggtgatt 1020 cagtatggga agatagtgtc ctggttagag atggaatatg gtttatcaga aaaggaatcg 1080 aaagcttctg aatcatttct ccttgctgcc tttctgaacc tggccatgtg ctacctgaag 1140 cttagagaat acaccaaagc tgttgaatgc tgtgacaagg cccttggact ggacagtgcc 1200 aatgagaaag gcttgtatag gaggggtgaa gcccagctgc tcatgaacga gtttgagtca 1260 gccaagggtg actttgagaa agtgctggaa gtaaaccccc agaataaggc tgcaagactg 1320 cagatctcca tgtgccagaa aaaggccaag gagcacaacg agcgggaccg caggatatac 1380 gccaacatgt tcaagaagtt tgcagagcag gatgccaagg aagaggccaa taaagcaatg 1440 ggcaagaaga cttcagaagg ggtcactaat gaaaaaggaa cagacagtca agcaatggaa 1500 gaagagaaac ctgagggcca cgtatgacgc cacgccaagg agggaagagt cccagtgaac 1560 tcggcccctc ctcaatgggc tttcccccaa ctcaggacag aacagtgttt aatgtaaagt 1620 ttgttatagt ctatgtgatt ctggaagcaa atggcaaaac cagtagcttc ccaaaaacag 1680 cccccctgct gctg 1694 <210> 407 <211> 2208 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(2208) <223> N=any base <400> 407 atgccaggga agcccaagca cttgggtgtc cccaacgggc gcatggttct ggctgtctca 60 gatggagaac tgaccagcac tgcaggttcc caggcccagg gtgagggcag aggcagctct 120 ctcagcatcc acagcctccc tagtggcccc agcagcccct tctccaccga ggagcagcct 180 gtggccagct gggcccagtc ctttgagcgg ctgctgcaag acccacgggg tctggcttac 240 ttcactgagt tcctgaagaa ggaattcagc gcagagaacg taactttctg gaaagcctgc 300 gaacgtttcc agcagatccc agccagcgac accaagcagc tagctcagga ggcccacaac 360 atctaccacg agttcctatc cagccaggcg ctgagcccag tgaacatcga ccgacaggcc 420 tggcttagtg aggaggtgct ggcccagccc cggccagata tgttccgagc acagcagctt 480 cagatcttca atttgatgaa gttcgacagc tatgcgcgct tcgtcaaatc cccgctgtac 540 caagagtgcc tgctggcgga ggccgaggga cgccccctgc gggaacctgg ctcctcacac 600 ctcgggagcc cggacacagc gaggaagaag ccaaagctga agcctgggaa gtcactgccg 660 ctgggcgtgg aagagttggg gcagctgcca ctcgctgagg gcccttgtgg ccgccctctc 720 cgcaagtcct ttcgtagaga gatgacaggt ggagccatga attcggccct gcgacgagag 780 tctcaagggt ccctgaattc ttctgccagt ctggacctgg gtttccttgc ctttgtgagc 840 agcaaatctg agagtcaccg gaagagcctt ggaagtggag agagtgagag cgagagtcgg 900 ccggggaagt attgctgcgt gtatctacct gacggcacgg cttccttggc cctggctcga 960 cctggcctca ccatccgaga catgctggca ggcatctgtg agaagagagg cctctctctg 1020 cctgacatta aggtctacct ggtgggcaat gaacagaagg ccctggtcct ggatcaggat 1080 tgcaccgtgc tggcagacca ggaagtgcga ctggaaaaca ggatcacctt ccagctggag 1140 ttggtcggcc tggagcgagt ggtccggatc tcagctaagc ccaccaagcg tctgcaagag 1200 gcgctgcagc ccatcctggc taagcatggc ctgagcctgg accaggtggt actgcacagg 1260 ccaggagaga agcagcccat ggatttggag actccagtga gctcagtggc ctcacagaca 1320 ctggttttgg acactcctcc ggatgcaaag atgagtgaag ccagaagcat atccccctgc 1380 cgcagtcagg gatgcctccc aagaacccag accaaggaca gtcaccttcc cccatcgtcc 1440 tccagtttgc tggtagaaga tgccagtagt tctactggga accggcagac ctgtgacatt 1500 gaaggcctgg tggagctgct gaatcgggtg cagagcagcg gggcccacga tcagagagga 1560 cttcttcgca aagaggacct ggtccttcca gaatttctgc agcttccttc ccaaagacca 1620 ggctctcggg aggctccacc atagactgaa tcaactattc agcccaggga ggcccttcag 1680 actccaccac ccacccggtc ctctggcatc tgtgtaacaa tccaggctat ctgcatggtg 1740 cctgggcaaa ccaagcatgc cacgggtctg tgctgcatgc cctatctgta ccatgagtgt 1800 ctttggctcc tttctgctat gggcaggcnn ccagaaaggg ccaggagggg ggggctaact 1860 gttctctcat aggtttgcct acccattcct cccagtaggc catcaagagg aggtgggcct 1920 agttccttgg cataagcata gtgaacacaa atgggtgact ttggcagtgc cagcctcctc 1980 aacttgttct aggctttagc agggggcagg aaggaggggc tggcccctcc ttaaagagtt 2040 gatataagta agacctgggt gtactggtga gcaacccctc cctccatcca cagactctac 2100 tgtacatatg gattttatgg ttggcttggg gcagctgggt ttgtcctgga tatatggtac 2160 tgttatataa taataataat tatcattatt aaaaaaaaag ctcgacca 2208 <210> 408 <211> 367 <212> DNA <213> HUMAN <400> 408 ctccaccatg aaactcgctg tcaccctcac cctggtcaca ctggctctct gctgcagctc 60 cgcttctgca gagatctgcc cgagctttca gcgtgtcatc gaaaccctcc tcatggacac 120 accctccagt tatgaggctg ccatggaact tttcagccct gatcaagaca tgagggaggc 180 aggggctcag ctgaagaagc tggtggacac cctcccccaa aagcccagag aaagcatcat 240 taagctcatg gaaaaaatag cccaaagctc actgtgtaat tagcatttag aagctgaaga 300 tccccaactg ctccagcctc tgccgctgcc atgctttgag tccacgccca ccagccttgc 360 tctcttc 367 <210> 409 <211> 3038 <212> DNA <213> HUMAN <400> 409 gcgtgaggaa agtaccaaac agcagcggag ttttaaactt taaatagaca ggtctgagtg 60 cctgaacttg ccttttcatt ttacttcatc ctccaaggag ttcaatcact tggcgtgact 120 tcactacttt taagcaaaag agtggtgccc aggcaacatg ggtgactgga gcgccttagg 180 caaactcctt gacaaggttc aagcctactc aactgctgga gggaaggtgt ggctgtcagt 240 acttttcatt ttccgaatcc tgctgctggg gacagcggtt gagtcagcct ggggagatga 300 gcagtctgcc tttcgttgta acactcagca acctggttgt gaaaatgtct gctatgacaa 360 gtctttccca atctctcatg tgcgcttctg ggtcctgcag atcatatttg tgtctgtacc 420 cacactcttg tacctggctc atgtgttcta tgtgatgcga aaggaagaga aactgaacaa 480 gaaagaggaa gaactcaagg ttgcccaaac tgatggtgtc aatgtggaca tgcacttgaa 540 gcagattgag ataaagaagt tcaagtacgg tattgaagag catggtaagg tgaaaatgcg 600 aggggggttg ctgcgaacct acatcatcag tatcctcttc aagtctatct ttgaggtggc 660 cttcttgctg atccagtggt acatctatgg attcagcttg agtgctgttt acacttgcaa 720 aagagatccc tgcccacatc aggtggactg tttcctctct cgccccacgg agaaaaccat 780 cttcatcatc ttcatgctgg tggtgtcctt ggtgtccctg gccttgaata tcattgaact 840 cttctatgtt ttcttcaagg gcgttaagga tcgggttaag ggaaagagcg acccttacca 900 tgcgaccagt ggtgcgctga gccctgccaa agactgtggg tctcaaaaat atgcttattt 960 caatggctgc tcctcaccaa ccgctcccct ctcgcctatg tctcctcctg ggtacaagct 1020 ggttactggc gacagaaaca attcttcttg ccgcaattac aacaagcaag caagtgagca 1080 aaactgggct aattacagtg cagaacaaaa tcgaatgggg caggcgggaa gcaccatctc 1140 taactcccat gcacagcctt ttgatttccc cgatgataac cagaattcta aaaaactagc 1200 tgctggacat gaattacagc cactagccat tgtggaccag cgaccttcaa gcagagccag 1260 cagtcgtgcc agcagcagac ctcggcctga tgacctggag atctagatac aggcttgaaa 1320 gcatcaagat tccactcaat tgtggagaag aaaaaaggtg ctgtagaaag tgcaccaggt 1380 gttaattttg atccggtgga ggtggtactc aacagcctta ttcatgaggc ttagaaaaca 1440 caaagacatt agaataccta ggttcactgg gggtgtatgg ggtagatggg tggagaggga 1500 ggggataaga gaggtgcatg ttggtattta aagtagtgga ttcaaagaac ttagattata 1560 aataagagtt ccattaggtg atacatagat aagggctttt tctccccgca aacaccccta 1620 agaatggttc tgtgtatgtg aatgagcggg tggtaattgt ggctaaatat ttttgtttta 1680 ccaagaaact gaaataattc tggccaggaa taaatacttc ctgaacatct taggtctttt 1740 caacaagaaa aagacagagg attgtcctta agtccctgct aaaacattcc attgttaaaa 1800 tttgcacttt gaaggtaagc tttctaggcc tgaccctcca ggtgtcaatg gacttgtgct 1860 actatatttt tttattcttg gtatcagttt aaaattcaga caaggcccac agaataagat 1920 tttccatgca tttgcaaata cgtatattct ttttccatcc acttgcacaa tatcattacc 1980 atcacttttt catcattcct cagctactac tcacattcat ttaatggttt ctgtaaacat 2040 ttttaagaca gttgggatgt cacttaacat tttttttttt tgagctaaag tcagggaatc 2100 aagccatgct taatatttaa caatcactta tatgtgtgtc gaagagtttg ttttgtttgt 2160 catgtattgg tacaagcaga tacagtataa actcacaaac acagatttga aaataatgca 2220 catatggtgt tcaaatttga acctttctca tggatttttg tggtgtgggc caatatggtg 2280 tttacattat ataattcctg ctgtggcaag taaagcacac tttttttttc tcctaaaatg 2340 tttttccctg tgtatcctat tatggatact ggttttgtta attatgattc tttattttct 2400 ctcctttttt taggatatag cagtaatgct attactgaaa tgaatttcct ttttctgaaa 2460 tgtaatcatt gatgcttgaa tgatagaatt ttagtactgt aaacaggctt tagtcattaa 2520 tgtgagagac ttagaaaaaa tgcttagagt ggactattaa atgtgcctaa atgaattttg 2580 cagtaactgg tattcttggg ttttcctact taatacacag taattcagaa cttgtattct 2640 attatgagtt tagcagtctt ttggagtgac cagcaacttt gatgtttgca ctaagatttt 2700 atttggaatg caagagaggt tgaaagagga ttcagtagta cacatacaac taatttattt 2760 gaactatatg ttgaagacat ctaccagttt ctccaaatgc cttttttaaa actcatcaca 2820 gaagattggt gaaaatgctg agtatgacac ttttcttctt gcatgcatgt cagctacata 2880 aacagttttg tacaatgaaa attactaatt tgtttgacat tccatgttaa actacggtca 2940 tgttcagctt cattgcatgt aatgtagacc tagtccatca gatcatgtgt tctggagagt 3000 gttctttatt caataaagtt ttaatttagt ataaacat 3038 <210> 410 <211> 597 <212> DNA <213> HUMAN <400> 410 atgaaggctg tcattattct ggggcttgtc ctcctttctg tcacggtcca gggcaagatc 60 tttgaaaggt gtgagttggc cagaactctg aaaagattgg gactggatgg ctacagggga 120 atcagcctag caaactgggt gtgtttggcc aaatgggaga gtaattataa cacacaagct 180 acaaactaca atcctggaga ccaaagcact gattatggga tatttcagat caatagccac 240 tactggtgta ataatggcaa aaccccagga gcagttaatg cctgtcatat atcctgcaat 300 gctttgctgc aagataacat cgctgatgct gtaacttgtg caaagagggt tgtcagtgat 360 ccacaaggca ttagagcatg ggtggcatgg agaaatcact gtcaaaacag agatgtcagt 420 cagtatgttc aaggttgtgg agtgtaattg cagaattttc cttcttcagc tcattttcgt 480 ctctttctca cattaaggga gtagtaatta agtgaaagat cacactacca ttatttcccc 540 ttcaaagaat atatttacag agcaggagca aaatatggct tcttctagag acgtatg 597 <210> 411 <211> 1446 <212> DNA <213> HUMAN <400> 411 ctcggaagga caggatgcca tgccatcggg aagacaggac tccccaagga gaacaggatg 60 ccatcaggga gacaggactc ccccgtggaa gataggatac ctccaggaag acagaatgcc 120 ccccaggcag ccctgggaca gcgggaaaca ctagggacca agctatccct ggttcactcg 180 ggattttgtt gggttgtggg cggggctcag gaaagattgt ccctgctggt cctgctccac 240 gaccacccac ccggcaaggt tccctcctag agaaccttgt cagagacaga acgggtcccc 300 acaggcgcat tcttctttcc aacacccatg gcgcagttcc tgagactttg catctggctc 360 gtagcgcttg ggtcctgcct cctggctaca gtgcaggcag actgcagcca ggactgcgct 420 aaatgcagct accgcctggt acgtcccggc gacatcaact tcctggcatg cacactcgaa 480 tgtgaagggc agctgccttc tttcaaaatc tgggagacct gcaaggatct cctgcaggtg 540 tccaagcccg agttcccttg ggataacatc gacatgtaca aagacagcag caaacaggat 600 gagagccact tgctagccaa gaagtatgga gggttcatga aacggtatgg aggcttcatg 660 aagaagatgg atgagcttta ccccgtggag ccagaagaag aggccaatgg aggcgagatc 720 cttgccaaga ggtatggcgg tttcatgaag aaggatgcag atgagggaga caccttggcc 780 aactcctccg acctgctgaa agagctactg ggaacaggag acaaccgtgc gaaagatagc 840 caccaacagg aaagcaccaa caatgatgaa gacagcacga gcaagaggta tgggggcttc 900 atgagaggcc tcaaaagaag cccccagctg gaagacgaag caaaggagct gcagaagcgc 960 tatgggggct tcatgagaag ggtcgggcgc cccgagtggt ggatggacta tcagaagaga 1020 tacggaggct tcctgaagcg ctttgctgag tctctaccct cggatgaaga aggcgaaagt 1080 tactctaaag aagttcccga gatggaaaaa agatacggag gctttatgcg gttttgaagc 1140 ccttcccagc agtgatcccg ggcccccact agcctgctcc atcccccgtg agcaactgcc 1200 ccatcagtga tgtttcttgt catgtgctgc ttgtgctgta cagttgccct cgtggtctgg 1260 ataactgctg cctgaaagct gtgattttta gggggttgtc tgtattcttt tgagtcttga 1320 agctcagtat tggtctcttg tggctatgtt atcatgctga aacagtctgt tacctcatcc 1380 cttctgacaa aacgtcaata aatgcttatt tgtatataaa aataataaac ccgtgaaccc 1440 aactgc 1446 <210> 412 <211> 216 <212> DNA <213> HUMAN <400> 412 aagagaacca gacccatgtt tatccctttg aaagaaacct gaaccaagcc attcctctgg 60 actgttcttc catccactgg accaataact catagtttga aggattttta cttaatggaa 120 gtgagaaaac agccagatca aaagaatttc caggagccaa gacagaaaac atgcagagca 180 ttagacagcc taaatggagc tggctagata tgactc 216 <210> 413 <211> 269 <212> DNA <213> HUMAN <400> 413 tggacagcct ggccggctgg aagccctccg tgtactacgt catgctgatc ctatgcacag 60 cctccatcct catctcttgc tgcgcctcag ccatgtacac ccccattgaa ggctggagct 120 actttgactc actctacttc tgttttgtgg ctttcagcac cattggcttt ggggacctgg 180 tcagcagcca gaacgcccac tatgagagcc aaggcctcta tcgctttgcc aacttcgtct 240 tcatcctcat gggtgtctgc tgcatctac 269 <210> 414 <211> 134 <212> DNA <213> HUMAN <400> 414 ctcacctggt gcaggtggac acctgcgcag gtgtgtgccc tccggcccct gaagcatggc 60 cagcagcggc atggctgaca gcgccaacca cctgcccatc tttttcggca acatcacccg 120 ggaggaggca gaag 134 <210> 415 <211> 105 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(105) <223> N=any base <400> 415 cngncattgc agtanatnna gctcnataga ganatcgccg ttggcaattg agtatgcgga 60 cgggnactgt gncgactctg tgcctcgctg aggaaaaata actaa 105 <210> 416 <211> 222 <212> DNA <213> HUMAN <400> 416 ctgggttccc gagtgcttga gctgtggctc ccgctgtagc tctgaccacg tggaaactca 60 agcctgcact cgggaacaga accgcatctg cacctacagg cccggctggt actgcgcgct 120 gagcaagcag gaggggtgcc ggctgtgcgc gccgctgcgc aagtgccgcc cgggcttcgg 180 cgtggccaga ccaggaactg aaacatcaga actggtgtgc aa 222 <210> 417 <211> 127 <212> DNA <213> HUMAN <400> 417 gggagtccgc tccagcgggg cgctccagtc cctcagacgt gggctgagct tgggacgagc 60 tgcgttccgc cccaggccac tgtagggaac ggcggtggcg cctccccagc aaaccggacc 120 gactggg 127 <210> 418 <211> 181 <212> DNA <213> HUMAN <400> 418 ggcttcacca tgcacagctg ggagcgcctg gcagttctgg tcctcctagt gagcggccgc 60 ctgcgcgggc cgccccgtgg tcggatcctg ggcggcagaa aaggccaagg gcgcacgcgc 120 ggccctacat ggcgtcggtg cagctgaacg gcgcgcacct gtgcggcggc gtcctggtgg 180 c 181 <210> 419 <211> 225 <212> DNA <213> HUMAN <400> 419 ctccgactgg acgcagcagc caccgacgcg tccctctctc cacgaggctg ccggcttagg 60 acccccagct ccgacatgtc ggcctctggt cggctgtgtc ttctcaacat cgttggactg 120 attctcccca ccagaggaca gacgttgaaa gataccacgt ccagttcttc agcagacgca 180 actatcatgg acattcaggt cccgacacga gccccagatg cagtc 225 <210> 420 <211> 476 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(476) <223> N=any base <400> 420 gactattaca aaagtttatt taacaaaaag tctaatatga aaatgtacat gacctaattt 60 ttacatcata gtaaaacagg ccctatggag agaggacatg ggtttctctg ctgaacagcc 120 attatttata ctcgttccaa ggcttctaac atgatgatac tatttcctcg tattaccacc 180 attccaatat tgttctgttg tccactagtc gccatctcca cacattcatc tatcacaagg 240 ttcataaagg gatcaaatcc ccgcaatatt ccttggacat gtctgccacc atttaatttc 300 aatgataact tcttgtccat aaattttttc aactcgggga gggtgagctt tgctcatngg 360 tgtatactcc gcgggctcac agatgccttt ggaacgcaac gcacggcttt cctcacgctc 420 ccgctgtagg cccggcgtct tgccctcgtg ccgaatttct tggccccgan ggcaaa 476 <210> 421 <211> 424 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(424) <223> N=any base <400> 421 caaggtcctg gtgatcactg tcttctgtgg tctgactgtg gctttccccc tgtcagaatt 60 agtttcaatc aataaagaac tacagaattc aatcattgac ctactaaact cagtctttga 120 ccaactggga tcatacagag ggacaaaagc tcctctagag gattatacag atgatgattt 180 aagcactgac tctgagcaga tcatggactt cacgccagcc gcaaacaaac agaattctga 240 gttctctact gatgttgaga cagtctcctc cggctttctg gaagaattca ctngagaaca 300 cagacatcac agtgaaaatt ccattagctg ggaatccagt ctcccctact tcctgagaag 360 actccaactt tgaaataaac ctgcgactgc cattcaggat attgtctttg tagaaaatga 420 tata 424 <210> 422 <211> 341 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(341) <223> N=any base <400> 422 gggggtgttc ggtccttgcg ggcttcacga gatcgattcc tgactacttt gctgtgaatt 60 gcacaactca cacagtaatg tagcttcaca tacagcttgg gaagcacata ggcatcgaag 120 acgctcgctt cagaaatgtc cctgactgct gcggcctcca ctatgtttcg aatgaccgaa 180 tttcttaatg ggccttgtcc ttgggcacgg catcggggca cagttaagtg cagcgaataa 240 ggctgcacgt gggccgcggg cccttttttg gcacgaccaa ttgttccttc cttttccttg 300 gcaatcttga aggaacgaac cgaagagagg aagacggtgc n 341 <210> 423 <211> 151 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(151) <223> N=any base <400> 423 ccagacccca agccngggcc atcccgccac tcgacgggtg gtgctcgnga cggcgtgcan 60 ntcccgcccg gggactacag cacgacnccc ggcggcacnt cattcagcac caccccgggg 120 angtaccagg atcatctatg accggaaatt c 151 <210> 424 <211> 442 <212> DNA <213> HUMAN <400> 424 ggctcggcgc gatggaggag gagacgcata ctgacgccaa aatccgtgct gaaaatggaa 60 cagggtccag ccctcggggt cctggctgca gcctccggca ctttgcctgc gaacagaacc 120 tgctgtcgcg gccagatggc tctgcttcct tcctgcaagg tgacacctct gtcctggcgg 180 gtgtgtacgg gccggccgag gtgaaggtca gcaaagagat tttcaacaag gccacactcg 240 aagtgatcct gaggccgaag attgggctgc ctgcatggca ttggtggatg caggtgtgcc 300 catgcgggct ctcttctgtg gggtcgcctg cgccctggac tctgatggga ccctcgtgct 360 ggatcctaca tccaagcaag aaaaggaggc ccgggcagtc ctgacctttg ccctggacag 420 cgtggaacga agctgctgat gt 442 <210> 425 <211> 446 <212> DNA <213> HUMAN <400> 425 tttttttttg agagattaag attcttttaa tggtgaaaag atatacatat atttggaact 60 agccagcttg actcagttta ggtgatccca attttggtgg caacaaccaa agcatcgtag 120 tcaggagcca gtcgaacata tgccttcctc tctccatcag actgaatcag agtgttgact 180 ttggccacat caatgtcaca aacttcttca cagcctgttt gatctggtgc ttgttggctt 240 taacatccac agtgaacaca agtaggctgt tgttttctat cttcttcaca gcctactcag 300 tggtcagcgg aaacttgatg ataacatggt ggtcaagctt atttctcctg ggggtgctct 360 tccaaggata tttgggctgc ctccggagtc acagtgtctt gggccgccgg aaggtgggtg 420 acatgtggat cttgtttttt ttgtgg 446 <210> 426 <211> 3074 <212> DNA <213> HUMAN <400> 426 ccgctctccg ctgcggggga ggccatggcg gaaccttccc aggccccgac cccggccccg 60 gctgcgcagc cccggcccct tcagtcccca gcccctgccc caactccgac tcctgcaccc 120 agcccggctt cagccccgat tccgactccc accccggcac cagcccctgc cccagctgca 180 gccccagccg gcagcacagg gactgggggg cccggggtag gaagtggggg ggccgggagc 240 gggggggatc cggctcggcc tggcctgagc cagcagcagc gcgccagtca gaggaaggcg 300 caagtccggg ggctgccccg cgccaagaag cttgagaagc taggggtctt ctcggcttgc 360 aaggccaatg gaacctgtaa gtgtaatggc tggaaaaacc ccaagccccc cactgcaccc 420 cgcatagatc tgcagcagcc agctgccaac ctgagtgagc tgtgccgcag ttgtgagcac 480 cccttggctg accacgtatc ccacttggag aatgtgtcag aggatgagat aaaccgactg 540 ctggggatgg tggtggatgt ggagaatctc ttcatgtctg ttcacaagga agaggacaca 600 gacaccaagc aggtctattt ctacctcttc aagctactgc ggaaatgcat cctgcagatg 660 acccggcctg tggtggaggg gtccctgggc agccctccat ttgagaaacc taatattgag 720 cagggtgtgc tgaactttgt gcagtacaag tttagtcacc tggctccccg ggagcggcag 780 acgatgttcg agctctcaaa gatgttcttg ctctgcctta actactggga gcttgagaca 840 cctgcccagt ttcggcagag gtctcaggct gaggacgtgg ctacctacaa ggtcaattac 900 accagatggc tctgttactg ccacgtgccc cagagctgtg atagcctccc ccgctacgaa 960 accactcatg tctttgggcg aagccttctc cggtccattt tcaccgttac ccgccggcag 1020 ctgctggaaa agttccgagt ggagaaggac aaattggtgc ccgagaagag gaccctcatc 1080 ctcactcact tccccaaatt cctgtccatg ctggaggagg agatctatgg ggcaaactct 1140 ccaatctggg agtcaggctt caccatgcca ccctcagagg ggacacagct ggttccccgg 1200 ccagcttcag tcagtgcagc ggttgttccc agcaccccca tcttcagccc cagcatgggt 1260 gggggcagca acagctccct gagtctggat tctgcagggg ccgagcctat gccaggcgag 1320 aagaggacgc tcccagagaa cctgaccctg gaggatgcca agcggctccg tgtgatgggt 1380 gacatcccca tggagctggt caatgaggtc atgctgacca tcactgaccc tgctgccatg 1440 ctggggcctg agacgagcct gctttcggcc aatgcggccc gggatgagac agcccgcctg 1500 gaggagcgcc gcggcatcat cgagttccat gtcatcggca actcactgac gcccaaggcc 1560 aaccggcggg tgttgctgtg gctcgtgggg ctgcagaatg tcttttccca ccagctgccg 1620 cgcatgccta aggagtatat cgcccgcctc gtctttgacc cgaagcacaa gactctggcc 1680 ttgatcaagg atgggcgggt catcggtggc atctgcttcc gcatgtttcc cacccagggc 1740 ttcacggaga ttgtcttctg tgctgtcacc tcgaatgagc aggtcaaggg ttatgggacc 1800 cacctgatga accacctgaa ggagtatcac atcaagcaca acattctcta cttcctcacc 1860 tacgccgacg agtacgccat cggctacttc aaaaagcagg gtttctccaa ggacatcaag 1920 gtgcccaaga gccgctacct gggctacatc aaggactacg agggagcgac gctgatggag 1980 tgtgagctga atccccgcat cccctacacg gagctgtccc acatcatcaa gaagcagaaa 2040 gagatcatca agaagctgat tgagcgcaaa caggcccaga tccgcaaggt ctacccgggg 2100 ctcagctgct tcaaggaggg cgtgaggcag atccctgtgg agagcgttcc tggcattcga 2160 gagacaggct ggaagccatt ggggaaggag aaggggaagg agctgaagga ccccgaccag 2220 ctctacacaa ccctcaaaaa cctgctggcc caaatcaagt ctcaccccag tgcctggccc 2280 ttcatggagc ctgtgaagaa gtcggaggcc cctgactact acgaggtcat ccgcttcccc 2340 attgacctga agaccatgac tgagcggctg cgaagccgct actacgtgac ccggaagctc 2400 tttgtggccg acctgcagcg ggtcatcgcc aactgtcgcg agtacaaccc cccggacagc 2460 gagtactgcc gctgtgccag cgccctggag aagttcttct acttcaagct caaggaggga 2520 ggcctcattg acaagtaggc ccatctttgg gccgcagccc tgacctggaa tgtctccacc 2580 tcggattctg atctgatcct tagggggtgc cctggcccca cggacccgac tcagcttgag 2640 acactccagc caagggtcct ccggacccga tcctgcagct ctttctggac cttcaggcac 2700 ccccaagcgt gcagctctgt cccagccttc actgtgtgtg agaggtctcc tgggttgggg 2760 cccagcccct ctagagtagc tggtggccag ggatgaacct tgcccagccg tggtggcccc 2820 caggcctggt ccccaagagc tttggaggct tggattcctg ggcctggccc aggtggctgt 2880 ttccctgagg accagaactg ctcattttag cttgagtgat ggcttcaggg gttggaagtt 2940 cagcccaaac tgaagggggc catgccttgt ccagcactgt tctgtcagtc tcccccaggg 3000 gtggggggta tggggaccat tcattccctg gcattaatcc cttagaggga ataataaagc 3060 tttttatttc tctg 3074 <210> 427 <211> 757 <212> DNA <213> HUMAN <400> 427 atgctggttc tctttgtggc cacatggagt gacctgggcc tctgcaagaa gcgcccgaag 60 cctggaggat ggaacactgg gggcagccga tacccggggc agggcagccc tggaggcaac 120 cgctacccac ctcagggcgg tggtggctgg gggcagcctc atggtggtgg ctgggggcag 180 cctcatggtg gtggctgggg gcagccccat ggtggtggct ggggacagcc tcatggtggt 240 ggctggggtc aaggaggtgg cacccacagt cagtggaaca agccgagtaa gccaaaaacc 300 aacatgaagc acatggctgg tgctgcagca gctggggcag tggtgggggg ccttggcggc 360 tacgtgctgg gaagtgccat gagcaggccc atcatacatt tcggcagtga ctatgaggac 420 cgttactatc gtgaaaacat gcaccgttac cccaaccaag tgtactacag gcccatggat 480 gagtacagca gccagaacaa ctttgtgcac gactgcgtca atatcacaat caagcagcac 540 acggtcacca caaccaccaa gggggagaac ttcaccgaga ccgacgttaa gatgatggag 600 cgcgtggttg agcagatgtg tatcacccag tacgagaggg aatctcaggc ctattaccag 660 agaggatcga gcatggtcct cttctcctct ccacctgtga tcctcctgat ctctttcctc 720 atcttcctga tagtgggatg aggaaggtct tcctgtt 757 <210> 428 <211> 468 <212> DNA <213> HUMAN <400> 428 tttttgcagt ttgaatcctg gtttatttaa gtagcattca ggagttatac tgtaaataaa 60 catcattatg gctaatgact aattaaaatc accattcatt acaaatacca accaggttag 120 ataatactat taactatctt ttccccttcg gtctggggtt catattcttc cttttctgga 180 agtcattttc atggataaaa tatttagcat tttttgttac ctcttccttc accaactgta 240 ctcaacacac ttctgtaaac agagtgagaa cctgggttca tggacaagct cttttccact 300 tatcttcggg ttaaaccaaa actttttcag caactttgcc cctgtccaag ttttgcagaa 360 caccagctgc ctcttcctgt tctaggcatt ctagggctag atacctgtga acggacttca 420 agcattaaag aagtcatcag catttcctat acctcacaca cactcatt 468 <210> 429 <211> 330 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(330) <223> N=any base <400> 429 ttttttttcc ggtatccact ggaagtttat ttctttaggg ttctatccca accagtcgct 60 taaaaaccaa gtaacacaga cctgaggggt gggggctggg gactgcacct ccctcctact 120 catggtggac agcagtgggg actagggagg ggcaggagag gtggctgaag caaggcagca 180 gtaatggggc cacgacgcca cagagccagc tccgtcctct cccagaccct ggtgggagtc 240 cctgggtggt gaaaaaaggg gggggaaanc accccaggcc ctncctctcc cttccttaaa 300 cagcctcctt tcgggctcaa cccatttctt 330 <210> 430 <211> 273 <212> DNA <213> HUMAN <400> 430 tttttaggat ttttagtatt ttaatataat acagttccaa tcagtgtgtc tggttcattt 60 cagttccttc actgccaaac cggggggcag ggactgcttc agtttctctg ccttctcttt 120 gtcagtgatg accagggtgt aaaggtatct gctgcatcga actttaaact tcacgttgtc 180 cttatttttc ttgatcttga cagatttggc atcctttcgt cgggctgtga gcaggaagtc 240 cttgatttcc tcaattttcc gaggcatggc gac 273 <210> 431 <211> 616 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(616) <223> N=any base <400> 431 tgatgtaaaa ttcagcttta ttagaattct cttaaaatgt ttgataatat acaagcagtc 60 tgactcccaa tgctttgtgt cattatacaa ataagaaaat aacttgcttt aattctaatg 120 cagcattttt taacctgcta aatagaacta acttcttgtt tctgaaatcc tgaacatatg 180 cctcattgaa ataccatttt caggacatcg ttttcccagc aaaaagcttc tttagataac 240 agaatcattt ggtatacaca gaacacgaat gatgactgca aggggaggct gcagggctgg 300 aggagggtta gagcaacaca gtttccagtt acagttgagt ccgggaagcc agcaccagaa 360 agaggggaat gataagaccc gccctttgtt ctgtataaag acttggggct tttctttgag 420 tagcggctgc tgccgacttt aaggcacagt caggatgggt gctgtggtcc acgcactgta 480 agagcttcac tggtcggtaa tcattaatac agctgtactg gaaacccatg tncttcagcc 540 tcttttnnca gactntcatg ctgncttccc cgcaggattc cacattgngt cccccaatnt 600 tcatgcatac ccagat 616 <210> 432 <211> 216 <212> DNA <213> HUMAN <400> 432 tttttatttc ttcagctaaa acagcggaag aggggattta ttatatggtt gttacactcg 60 gccacaaata aacacagaaa tagtccagaa tgtcacaggt ccagggcaga ggaccaacat 120 gggcattttg tttatgagca aggtgggtct cagaggtgat cggcgatcag agggcgatga 180 agttctagat ccattgagac aagctctaga cagtag 216 <210> 433 <211> 534 <212> DNA <213> HUMAN <400> 433 tccaaggggc tgtttaagat ggcggaggtg catgtcctgg tgcttgatgg tcgaggccat 60 ctcctgggcc gcctggcggc catcgtggct aaacaggtac tgctgggccg gaaggtggtg 120 gtcgtacgct gtgaaggcat caacatttct ggcaatttct acagaaacaa gttgaagtac 180 ctggctttcc tccgcaagcg gatgaacacc aacccttccc gaggccccta ccacttccgg 240 gcctccagcc gcatcttctg gcggaccgtg cgaggtatgc tgccccacaa aaccaagcga 300 ggccaggccg ctctggaccg tctcaaggtg tttgacggca tcccaccgcc ctacgacaag 360 aaaaagcgga tggtggttcc tgctgccctc aaggtcgtgc gtctgaagcc tacaagaaag 420 tttgcctatc tgcggcgcct ggctcacgag gttggctgga agtaccaggc agcgacagcc 480 accctgtagg agaagaggaa agagaaagcc aagatccact accggaagaa gaac 534 <210> 434 <211> 434 <212> DNA <213> HUMAN <400> 434 gaactatagc agatgaaata aaatatatat ctgttaaatg tcagagagca agttagacac 60 acattccact aagcatcaaa ggccctcgta gtctcggtgg aaggacaaac tccagctcca 120 catcactggt ttaagtttct tcctcttctt cttcctcttc ttcctcctcc tcttcctcct 180 catcttcatc agagctgaag gtgccatcag ggaggctgta gacacggatg acctgcttgt 240 tggggtcctt gaggatgagg tatttgccct cctccagctt catgcagatg tcaatgacgc 300 agcgtaaaat gccccaggca ttctccacgc tcaaggttga tctggctggc aaactcatta 360 ggcttgaact gctgggtgcc tatgatgacc tggcgtgaaa gagtctttca ccgtggttac 420 cgagacacat aacc 434 <210> 435 <211> 655 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(655) <223> N=any base <400> 435 attataaaag tgtgctttat tgtaaggaaa atttaaatat aaccaacaat actgaaaata 60 atgtacgtgg catttatagc cttggtcaaa gttctttatt aaacaggcgt ttgctgttcc 120 atgaatagtt aacaattagt ttatgcaaca aaatagataa cttgaaaaag tgagtaagaa 180 tacagaatga tgaaccagga atctggagtt cttttgtgtt ttttcttgtt taacagacat 240 ggcttttaaa ataaaatctg aaatataaaa caagtcatct tcatgtagag agctctcttt 300 tcctacaaga aggttttgca aaaatgttaa acagtgttct aaaaatgtgg ctgaagttat 360 actttacata ctttaacttc ttatatatac attatccaat taacattcta accacatttt 420 catatacaag tgggaccata aacattctct agtaagacta cactagcaca gagtaatttt 480 acccatgtat atatattcat ttgaaacctg tttccaaaat gaaatcactc atttaaaagc 540 aaacaactgg ttagaattaa tgtctctaga cactgggtca tggggcctag aaatcatgtt 600 agagtatatt tgctttgttg aatattatta aattcatctt atgttgcanc atact 655 <210> 436 <211> 428 <212> DNA <213> HUMAN <400> 436 ttgggtacca aatttcttta tttgaaggaa tggtacaaat caaagaactt aagtggatgt 60 tttggtacaa cttatagaaa aggtaaagga aaccccaaca tgcatgcact gccttggtga 120 ccagggaagt caccccacgg ctatggggaa attagcccga ggcttagctt tcattatcac 180 tgtctcccag ggtgtgcttg tcaaagagat attccgccaa gccagattcg ggcgctccca 240 tcttgcgcaa gttggtcacg tggtcaccca attctttgat ggctttcacc tgctcattca 300 ggtaatgtgt ctcaatgaag tcacacaaat gggggtcatt tttgtcagtg gccagtttgt 360 gcagttccag tagtgactga ttcacatttt tttccaaatg taatgcacac tccattgcat 420 tcagcccg 428 <210> 437 <211> 1128 <212> DNA <213> HUMAN <400> 437 agtccgagtg gagagagcga gctgagtggt tgtgtggtcg cgtctcggaa accggtagcg 60 cttgcagcat ggctgaccaa ctgactgaag agcagattgc agaattcaaa gaagcttttt 120 cactatttga caaagatggt gatggaacta taacaacaaa ggaattggga actgtaatga 180 gatctcttgg gcagaatccc acagaagcag agttacagga catgattaat gaagtagatg 240 ctgatggtaa tggcacaatt gacttccctg aatttctgac aatgatggca agaaaaatga 300 aagacacaga cagtgaagaa gaaattagag aagcattccg tgtgtttgat aaggatggca 360 atggctatat tagtgctgca gaacttcgcc atgtgatgac aaaccttgga gagaagttaa 420 cagatgaaga agttgatgaa atgatcaggg aagcagatat tgatggtgat ggtcaagtaa 480 actatgaaga gtttgtacaa atgatgacag caaagtgaag accttgtaca gaatgtgtta 540 aatttcttgt acaaaattgt ttatttgcct tttctttgtt tgtaacttat ctgtaaaagg 600 tttctcccta ctgtcaaaaa aatatgcatg tatagtaatt aggacttcat tcctccatgt 660 tttcttccct tatcttactg tcattgtcct aaaaccttat tttagaaaat tgatcaagta 720 acatgttgca tgtggcttac tctggatata tctaagccct tctgcacatc taaacttaga 780 tggagttggt caaatgaggg aacatctggg ttatgccttt tttaaagtag ttttctttag 840 gaactgtcag catgttgttg ttgaagtgtg gagttgtaac tctgcgtgga ctatggacag 900 tcaacaatat gtacttaaaa gttgcactat tgcaaaacgg gtgtattatc caggtactcg 960 tacactattt ttttgtactg ctggtcctgt accagaaaca ttttctttta ttgttacttg 1020 ctttttaaac tttgtttagc cacttaaaat ctgcttatgg cacaatttgc ctcaaaatcc 1080 attccaagtt gtatatttgt tttccaataa aaaaattaca atttaccc 1128 <210> 438 <211> 2133 <212> DNA <213> HUMAN <400> 438 cgggagagcg cgctctgcct gccgcctgcc tgcctgccac tgagggttcc cagcaccatg 60 agggcctgga tcttctttct cctttgcctg gccgggaggg ccttggcagc ccctcagcaa 120 gaagccctgc ctgatgagac agaggtggtg gaagaaactg tggcagaggt gactgaggta 180 tctgtgggag ctaatcctgt ccaggtggaa gtaggagaat ttgatgatgg tgcagaggaa 240 accgaagagg aggtggtggc ggaaaatccc tgccagaacc accactgcaa acacggcaag 300 gtgtgcgagc tggatgagaa caacaccccc atgtgcgtgt gccaggaccc caccagctgc 360 ccagccccca ttggcgagtt tgagaaggtg tgcagcaatg acaacaagac cttcgactct 420 tcctgccact tctttgccac aaagtgcacc ctggagggca ccaagaaggg ccacaagctc 480 cacctggact acatcgggcc ttgcaaatac atcccccctt gcctggactc tgagctgacc 540 gaattccccc tgcgcatgcg ggactggctc aagaacgtcc tggtcaccct gtatgagagg 600 gatgaggaca acaaccttct gactgagaag cagaagctgc gggtgaagaa gatccatgag 660 aatgagaagc gcctggaggc aggagaccac cccgtggagc tgctggcccg ggacttcgag 720 aagaactata acatgtacat cttccctgta cactggcagt tcggccagct ggaccagcac 780 cccattgacg ggtacctctc ccacaccgag ctggctccac tgcgtgctcc cctcatcccc 840 atggagcatt gcaccacccg ctttttcgag acctgtgacc tggacaatga caagtacatc 900 gccctggatg agtgggccgg ctgcttcggc atcaagcaga aggatatcga caaggatctt 960 gtgatctaaa tccactcctt ccacagtacc ggattctctc tttaaccctc cccttcgtgt 1020 ttcccccaat gtttaaaatg tttggatggt ttgttgttct gcctggagac aaggtgctaa 1080 catagattta agtgaataca ttaacggtgc taaaaatgaa aattctaacc caagacatga 1140 cattcttagc tgtaacttaa ctattaaggc cttttccaca cgcattaata gtcccatttt 1200 tctcttgcca tttgtagctt tgcccattgt cttattggca catgggtgga cacggatctg 1260 ctgggctctg ccttaaacac acattgcagc ttcaactttt ctctttagtg ttctgtttga 1320 aactaatact taccgagtca gactttgtgt tcatttcatt tcagggtctt ggctgcctgt 1380 gggcttcccc aggtggcctg gaggtgggca aagggaagta acagacacac gatgttgtca 1440 aggatggttt tgggactaga ggctcagtgg tgggagagat ccctgcagaa tccaccaacc 1500 agaacgtggt ttgcctgagg ctgtaactga gagaaagatt ctggggctgt cttatgaaaa 1560 tatagacatt ctcacataag cccagttcat caccatttcc tcctttacct ttcagtgcag 1620 tttcttttca cattaggctg ttggttcaaa cttttgggag cacggactgt cagttctctg 1680 ggaagtggtc agcgcatcct gcagggcttc tcctcctctg tcttttggag aaccagggct 1740 cttctcaggg gctctaggga ctgccaggct gtttcagcca ggaaggccaa aatcaagagt 1800 gagatgtaga aagttgtaaa atagaaaaag tggagttggt gaatcggttg ttctttcctc 1860 acatttggat gattgtcata aggtttttag catgttcctc cttttcttca ccctcccctt 1920 tgttcttcta ttaatcaaga gaaacttcaa agttaatggg atggtcggat ctcacaggct 1980 gagaactcgt tcacctccaa gcatttcatg aaaaagctgc ttcttattaa tcatacaaac 2040 tctcaccatg atgtgaagag tttcacaaat ctttcaaaat aaaaagtaat gacttagaaa 2100 ctgaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa 2133 <210> 439 <211> 2591 <212> DNA <213> HUMAN <400> 439 gcggccgcgt gaggcggaac tctgagcagg tggtccatta tggctgacat gcaaaatctg 60 gtagaaagat tggagagggc agtgggccgc ctggaggcag tatctcatac ctctgacatg 120 caccgtgggt atgcagacag tccttcaaaa gcaggagcag ctccatatgt gcaggcattt 180 gactcgctgc ttgctggtcc tgtggcagag tacttgaaga tcagtaaaga gattggggga 240 gacgtgcaga aacatgcgga gatggtccac acaggtttga agttggagcg agctctgttg 300 gttacagctt ctcagtgtca acagccagca gaaaataagc tttccgattt gttggcaccc 360 atctcagagc agatcaaaga agtgataacc tttcgggaga agaaccgagg cagcaagttg 420 tttaatcacc tgtcagctgt cagcgaaagt atccaggccc tgggctgggt ggctatggct 480 cccaagcctg gcccttatgt gaaagaaatg aatgatgccg ccatgtttta tacaaaccga 540 gtcctcaaag agtacaaaga tgtggataag aagcatgtag actgggtcaa agcttattta 600 agtatatgga cagagctgca ggcttacatt aaggagttcc ataccaccgg actggcctgg 660 agcaaaacgg ggcctgtggc aaaagaactg agcggactgc catctggacc ctctgccgga 720 tcaggtcctc ctccccctcc accaggcccc cctcctcccc cagtctctac cagttcaggc 780 tcagatgagt ctgcttcccg ctcagcactg ttcgcgcaga ttaatcaggg ggagagcatt 840 acacatgccc tgaaacatgt atctgatgac atgaagactc acaagaaccc tgccctgaag 900 gctcagagtg gtccagtacg cagtggcccc aaaccattct ctgcacctaa accccaaacc 960 agcccatccc ccaaacgagc cacaaagaag gagccagctg tacttgaact ggagggcaag 1020 aagtggagag tggaaaatca ggaaaatgtt tccaacctgg tgattgagga cacagagctg 1080 aaacaggtgg cttacatata caagtgtgtc aacacgacat tgcaaatcaa gggcaaaatt 1140 aactccatta cagtagataa ctgtaagaaa cttggcctgg tattcgatga cgtggtgggc 1200 attgtggaga taatcaacag taaggatgtc aaagttcagg taatgggtaa agtgccaacc 1260 atatccatca acaaaacaga tggctgccat gcttacctga gcaagaattc cctggattgt 1320 gaaatagtca gtgccaaatc ttccgagatg aatgtcctca ttcctacaga aggcggtgac 1380 tttaatgaat tcccagttcc tgagcagttc aagaccctat ggaacgggca gaagttggtc 1440 accacagtga cagaaattgc tggataagcg aagtgccact gggttctttg ccctcccttc 1500 acaccatggg ataaatctgt atcaagacgg ttcttttcta gatttcctct acctttttgc 1560 tcttaaaact gcttctctgc tctgagaagc acagctacct gccttcactg aaatatacct 1620 caggctgaga tttggggtgg gatagcaggt cagttgatct tctgcaggaa ggtgcagctt 1680 ttccatatca gctcaaccac gccgccagtc cattcttaag gaactgccga ctaggactga 1740 tgatgcattt tagctttgag cttttggggg ttattctacc aacaaacagt ccattggaaa 1800 gaaaacagtc cctggaatta acagatcaga atgttcacac tggttaatct ttttttaaca 1860 atgagcatga aggtagcaga agctggtgtg tttccagatg gttcttctaa ccaaactaat 1920 ttttcactgt tgacaagcga ggcaagggtt gcactggacc aaaggctgag gcttggccat 1980 ctagcattcc atacaaaatt gtttcctata agcattcctt ttattctcta ttctatcctg 2040 ggtctgcctc aaccgtgaga taggagagtc tctggtacta gctgctgtag cagtgccctt 2100 catccagggc agttaatgga gtcttggacc ctttctttct ctgggatccc tgcccagcac 2160 cttcctatag agatgacttt aaaaggaaaa aaaaaaaaaa acccacatga tttcaaggag 2220 tctggcattc ctgaatcctt cttccctgcc aggtgcctgt cacctgtctt cactgcctcc 2280 ttttccctgt catgctcatc agcttatggc ttctgtctaa gcacctgaac agaggactga 2340 aacctccact gcaggctggt tttaggtctt gaattatgta agaatcttgc acagcactgc 2400 taatgtaaat ttcagttgtt tttccctcta ggacaaacac ttaccaaaat atgcaacttt 2460 tttttggtgg gaagagagat tgtcctgtga tttctaccca tttcctgagg cctgtggaaa 2520 taaaccttta tgtacttaaa gttatacaga aaatagaata aagttaatac caaacttgaa 2580 aaagcggccg c 2591 <210> 440 <211> 2030 <212> DNA <213> HUMAN <400> 440 tggctggcaa tggccttgct gacctcgagc cgggcccacg tggggacctt tggagcacag 60 cctacgatcc tggtgcaagg ccggtggatg cagaggccag tccatatacc acccaggcct 120 gcgaggagcg tggtccccac ccatccagcc catatgtgca agtgcccttg acagagaggc 180 tggtcatatc catggtgacc atttatgggc cacaacaggt ccccatctgc gcagtgaacc 240 ctgtgctgag caccttgcag acgtgatctt gcttcgtcct gcagcactgt gcggggcagg 300 aaaatccaag aggaagaagg atctacggat atcctgcatg tccaagccac ccgcacccaa 360 ccccacaccc ccccggaacc tggactcccg gaccttcatc accattggag acagaaactt 420 tgaggtggag gctgatgact tggtgaccat ctcagaactg ggccgtggag cctatggggt 480 ggtagagaag gtgcggcacg cccagagcgg caccatcatg gccgtgaagc ggatccgggc 540 caccgtgaac tcacaggagc agaagcggct gctcatggac ctggacatca acatgcgcac 600 ggtcgactgt ttctacactg tcaccttcta cggggcacta ttcagagagg gagacgtgtg 660 gatctgcatg gagctcatgg acacatcctt ggacaagttc taccggaagg tgctggataa 720 aaacatgaca attccagagg acatccttgg ggagattgct gtgtctatcg tgcgggccct 780 ggagcatctg cacagcaagc tgtcggtgat ccacagagat gtgaagccct ccaatgtcct 840 tatcaacaag gagggccatg tgaagatgtg tgactttggc atcagtggct acttggtgga 900 ctctgtggcc aagacgatgg atgccggctg caagccctac atggcccctg agaggatcaa 960 cccagagctg aaccagaagg gctacaatgt caagtccgac gtctggagcc tgggcatcac 1020 catgattgag atggccatcc tgcggttccc ttacgagtcc tgggggaccc cgttccagca 1080 gctgaagcag gtggtggagg agccgtcccc ccagctccca gccgaccgtt tctcccccga 1140 gtttgtggac ttcactgctc agtgcctgag gaagaacccc gcagagcgta tgagctacct 1200 ggagctgatg gagcacccct tcttcacctt gcacaaaacc aagaagacgg acattgctgc 1260 cttcgtgaag aagatcctgg gagaagactc ataggggctg ggcctcggac cccactccgg 1320 ccctccagag ccccacagcc ccatctgcgg gggcagtgct cacccacacc ataagctact 1380 gccatcctgg cccagggcat ctgggaggaa ccgagggggc tgctcccacc tggctctgtg 1440 gcgagccatt tgtcccaagt gccaaagaag cagaccattg gggctcccag ccaggccctt 1500 gtcggcccca ccagtgcctc tccctgctgc tcctaggacc cgtctccagc tgctgagatc 1560 ctggactgag ggggcctgga tgccccctgt ggatgctgct gcccctgcac agcaggctgc 1620 cagtgcctgg gtggatgggc caccgccttg cccagcctgg atgccatcca agttgtatat 1680 ttttttaatc tctcgactga atggactttg cacactttgg cccagggtgg ccacacctct 1740 atcccggctt tggtgcgggg tacacaagag gggatgagtt gtgtgaatac cccaagactc 1800 ccatgaggga gatgccatga gccgcccaag gccttcccct ggcactggca aacagggcct 1860 ctgcggagca cactggctca cccagtcctg cccgccaccg ttatcggtgt cattcacctt 1920 tcgtgttttt tttaatttat cctctgttga ttttttcttt tgctttatgg gtttggcttg 1980 tttttcttgc atggtttgga gctgatcgct tctcccccac cccctagggg 2030 <210> 441 <211> 1457 <212> DNA <213> HUMAN <400> 441 cccaggcctc gcgctgcccg gccggctcct cgtgtcccac tcccggcgca cgccctcccg 60 cgagtcccgg gcccctcccg cgcccctctt ctcggcgcgc gcgcagcatg gcgcccccgc 120 aggtcctcgc gttcgggctt ctgcttgccg cggcgacggc gacttttgcc gcagctcagg 180 aagaatgtgt ctgtgaaaac tacaagctgg ccgtaaactg ctttgtgaat aataatcgtc 240 aatgccagtg tacttcagtt ggtgcacaaa atactgtcat ttgctcaaag ctggctgcca 300 aatgtttggt gatgaaggca gaaatgaatg gctcaaaact tgggagaaga gcaaaacctg 360 aaggggccct ccagaacaat gatgggcttt atgatcctga ctgcgatgag agcgggctct 420 ttaaggccaa gcagtgcaac ggcacctcca cgtgctggtg tgtgaacact gctggggtca 480 gaagaacaga caaggacact gaaataacct gctctgagcg agtgagaacc tactggatca 540 tcattgaact aaaacacaaa gcaagagaaa aaccttatga tagtaaaagt ttgcggactg 600 cacttcagaa ggagatcaca acgcgttatc aactggatcc aaaatttatc acgagtattt 660 tgtatgagaa taatgttatc actattgatc tggttcaaaa ttcttctcaa aaaactcaga 720 atgatgtgga catagctgat gtggcttatt attttgaaaa agatgttaaa ggtgaatcct 780 tgtttcattc taagaaaatg gacctgacag taaatgggga acaactggat ctggatcctg 840 gtcaaacttt aatttattat gttgatgaaa aagcacctga attctcaatg cagggtctaa 900 aagctggtgt tattgctgtt attgtggttg tggtgatagc agttgttgct ggaattgttg 960 tgctggttat ttccagaaag aagagaatgg caaagtatga gaaggctgag ataaaggaga 1020 tgggtgagat gcatagggaa ctcaatgcat aactatataa tttgaagatt atagaagaag 1080 ggaaatagca aatggacaca aattacaaat gtgtgtgcgt gggacgaaga catctttgaa 1140 ggtcatgagt ttgttagttt aacatcatac atttgtaata gtgaaacctg tactcaaaat 1200 ataagcagct tgaaactggc tttaccaatc ttgaaatttg accacaagtg tcttatatat 1260 gcagatctaa tgtaaaatcc agaacttgga ctccatcgtt aaaattattt atgtgtaaca 1320 ttcaaatgtg tgcattaaat atgcttccac agtaaaatct gaaaaactga tttgtgattg 1380 aaagctgcct ttctatttac ttgagtcttg tacatacata cttttttatg agctatgaaa 1440 taaaacattt taaactg 1457 <210> 442 <211> 744 <212> DNA <213> HUMAN <400> 442 ttggtacttg gaaaaatgga caaggattgt gaaatgaaac gcaccacact ggacagccct 60 ttggggaagc tggagctgtc tggttgtgag cagggtctgc acgaaataaa gctcctgggc 120 aaggggacgt ctgcagctga tgccgtggag gtcccagccc ccgctgcggt tctcggaggt 180 ccggagcccc tgatgcagtg cacagcctgg ctgaatgcct atttccacca gcccgaggct 240 atcgaagagt tccccgtgcc ggcacttcac catcccgttt tccagcaaga gtcgttcacc 300 agacaggtgt tatggaagct gctgaaggtt gtgaaattcg gagaagtgat ttcttaccag 360 caattagcag ccctggcagg caaccccaaa gccgcgcgag cagtgggagg agcaatgaga 420 ggcaatcctg tccccatcct catcccgtgc cacagagtgg tctgcagcag cggagccgtg 480 ggcaactact ccggaggact ggccgtgaag gaatggcttc tggcccatga aggccaccgg 540 ttggggaagc caggcttggg agggagctca ggtctggcag gggcctggct caagggagcg 600 ggagctacct cgggctcccc gcctgctggc cgaaactgag tatgtgcagt aggatggatg 660 tttgagcgac acacacgtgt aacactgcat cggatgcggg gcgtggaggc accgctgtat 720 taaaggaagt ggcagtgtcc tggg 744 <210> 443 <211> 1587 <212> DNA <213> HUMAN <400> 443 gggcgagggg cggacaccgg agagacacgg gaaaggggtc gggacaggag cacgtggctc 60 agacaccgac gccgggaggc cgcagacccc ggacgtgtca ggcatccccg caggcccgga 120 gcgatggcag ccttgatgac cccgggaacc ggggccccac ccgcgcctgg tgacttctcc 180 ggggaaggga gccagggact tcccgaccct tcgccagagc ccaagcagct cccggagctg 240 atccgcatga agcgagacgg aggccgcctg agcgaagcgg acatcagggg cttcgtggcc 300 gctgtggtga atgggagcgc gcagggcgca cagatcgggg ccatgctgat ggccatccga 360 cttcggggca tggatctgga ggagacctcg gtgctgaccc aggccctggc tcagtcggga 420 cagcagctgg agtggccaga ggcctggcgc cagcagcttg tggacaagca ttccacaggg 480 ggtgtgggtg acaaggtcag cctggtcctc gcacctgccc tggcggcatg tggctgcaag 540 gtgccaatga tcagcggacg tggtctgggg cacacaggag gcaccttgga taagctggag 600 tctattcctg gattcaatgt catccagagc ccagagcaga tgcaagtgct gctggaccag 660 gcgggctgct gtatcgtggg tcagagtgag cagctggttc ctgcggacgg aatcctatat 720 gcagccagag atgtgacagc caccgtggac agcctgccac tcatcacagc ctccattctc 780 agtaagaaac tcgtggaggg gctgtccgct ctggtggtgg acgttaagtt cggaggggcc 840 gccgtcttcc ccaaccagga gcaggcccgg gagctggcaa agacgctggt tggcgtggga 900 gccagcctag ggcttcgggt cgcggcagcg ctgaccgcca tggacaagcc cctgggtcgc 960 tgcgtgggcc acgccctgga ggtggaggag gcgctgctct gcatggacgg cgcaggcccg 1020 ccagacttaa gggacctggt caccacgctc gggggcgccc tgctctggct cagcggacac 1080 gcggggactc aggctcaggg cgctgcccgg gtggccgcgg cgctggacga cggctcggcc 1140 cttggccgct tcgagcggat gctggcggcg cagggcgtgg atcccggtct ggcccgagcc 1200 ctgtgctcgg gaagtcccgc agaacgccgg cagctgctgc ctcgcgcccg ggagcaggag 1260 gagctgctgg cgcccgcaga tggcaccgtg gagctggtcc gggcgctgcc gctggcgctg 1320 gtgctgcacg agctcggggc cgggcgcagc cgcgctgggg agccgctccg cctgggggtg 1380 ggcgcagagc tgctggtcga cgtgggtcag aggctgcgcc gtgggacccc ctggctccgc 1440 gtgcaccggg acggccccgc gctcagcggc ccgcagagcc gcgccctgca ggaggcgctc 1500 gtactctccg accgcgcgcc attcgccgcc ccctcgccct tcgcagagct cgttctgccg 1560 ccgcagcaat aaagctcctt tgccgcg 1587 <210> 444 <211> 2110 <212> DNA <213> HUMAN <400> 444 gtgaagtgct cagaatgggg caggatgtca cctggaatca gcactaagtg attcagactt 60 tccttacttt taaatgtgct gctcttcatt tcaagatgcc gttgcagctc tgataaatgc 120 aaactgacaa ccttcaaggc cacgacggag ggaaaatcat tggtgcttgg agcatagaag 180 actgcccttc acaaaggaaa tccctgatta ttgtttgaaa tgctgaggac gttgctgcga 240 aggagacttt tttcttatcc caccaaatac tactttatgg ttcttgtttt atccctaatc 300 accttctccg ttttaaggat tcatcaaaag cctgaatttg taagtgtcag acacttggag 360 cttgctgggg agaatcctag tagtgatatt aattgcacca aagttttaca gggtgatgta 420 aatgaaatcc aaaaggtaaa gcttgagatc ctaacagtga aatttaaaaa gcgccctcgg 480 tggacacctg acgactatat aaacatgacc agtgactgtt cttctttcat caagagacgc 540 aaatatattg tagaacccct tagtaaagaa gaggcggagt ttccaatagc atattctata 600 gtggttcatc acaagattga aatgcttgac aggctgctga gggccatcta tatgcctcag 660 aatttctatt gcgttcatgt ggacacaaaa tccgaggatt cctatttagc tgcagtgatg 720 ggcatcgctt cctgttttag taatgtcttt gtggccagcc gattggagag tgtggtttat 780 gcatcgtgga gccgggttca ggctgacctc aactgcatga aggatctcta tgcaatgagt 840 gcaaactgga agtacttgat aaatctttgt ggtatggatt ttcccattaa aaccaaccta 900 gaaattgtca ggaagctcaa gttgttaatg ggagaaaaca acctggaaac ggagaggatg 960 ccatcccata aagaagaaag gtggaagaag cggtatgagg tcgttaatgg aaagctgaca 1020 aacacaggga ctgtcaaaat gcttcctcca ctcgaaacac ctctcttttc tggcagtgcc 1080 tacttcgtgg tcagtaggga gtatgtgggg tatgtactac agaatgaaaa aatccaaaag 1140 ttgatggagt gggcacaaga cacatacagc cctgatgagt atctctgggc caccatccaa 1200 aggattcctg aagtcccggg ctcactccct gccagccata agtatgatct atctgacatg 1260 caagcagttg ccaggtttgt caagtggcag tactttgagg gtgatgtttc caagggtgct 1320 ccctacccgc cctgcgatgg agtccatgtg cgctcagtgt gcattttcgg agctggtgac 1380 ttgaactgga tgctgcgcaa acaccacttg tttgccaata agtttgacgt ggatgttgac 1440 ctctttgcca tccagtgttt ggatgagcat ttgagacaca aagctttgga gacattaaaa 1500 cactgaccat tacgggcaat tttatgaaca agaagaagga tacacaaaac gtaccttatc 1560 tgtttcccct tccttgtcag cgtcgggaag atggtatgaa gtcctctttg gggcagggac 1620 tctagtagat cttcttgtca gagaagctgc atggtttctg cagagcacag ttagctagaa 1680 aggtgatagc attaaatgtt catctagagt taatagtggg aggagtaaag gtagccttga 1740 ggccagagca ggtagcaagg cattgtggaa agaggggacc agggtggctg gggaagaggc 1800 cgatgcataa agtcagcctg ttccaagtgc tcagggactt agcaaaatga gaagatgtga 1860 cctgtgccaa aactattttg agaattttaa atgtgaccat ttttctggta tgccaataaa 1920 ddcttacagc aacaaataat caaagataca attaatctga tattatattt gttgaaatag 1980 aaatttgatt gtactataaa tgatttttgt aaataattta tattctgctc taatactgta 2040 ctgtgtagtg tgtctccgta tgtcatctca gggagcttaa aatgggcttg atttaacatt 2100 gaaaaaaaat 2110 <210> 445 <211> 1619 <212> DNA <213> HUMAN <400> 445 ccgccagatt tgaatcgcgg gacccgttgg cagaggtggc ggcggcggca tgggtgcccc 60 gacgttgccc cctgcctggc agccctttct caaggaccac cgcatctcta cattcaagaa 120 ctggcccttc ttggagggct gcgcctgcac cccggagcgg atggccgagg ctggcttcat 180 ccactgcccc actgagaacg agccagactt ggcccagtgt ttcttctgct tcaaggagct 240 ggaaggctgg gagccagatg acgaccccat agaggaacat aaaaagcatt cgtccggttg 300 cgctttcctt tctgtcaaga agcagtttga agaattaacc cttggtgaat ttttgaaact 360 ggacagagaa agagccaaga acaaaattgc aaaggaaacc aacaataaga agaaagaatt 420 tgaggaaact gcgaagaaag tgcgccgtgc catcgagcag ctggctgcca tggattgagg 480 cctctggccg gagctgcctg gtcccagagt ggctgcacca cttccagggt ttattccctg 540 gtgccaccag ccttcctgtg ggccccttag caatgtctta ggaaaggaga tcaacatttt 600 caaattagat gtttcaactg tgctcctgtt ttgtcttgaa agtggcacca gaggtgcttc 660 tgcctgtgca gcgggtgctg ctggtaacag tggctgcttc tctctctctc tctctttttt 720 gggggctcat ttttgctgtt ttgattcccg ggcttaccag gtgagaagtg agggaggaag 780 aaggcagtgt cccttttgct agagctgaca gctttgttcg cgtgggcaga gccttccaca 840 gtgaatgtgt ctggacctca tgttgttgag gctgtcacag tcctgagtgt ggacttggca 900 ggtgcctgtt gaatctgagc tgcaggttcc ttatctgtca cacctgtgcc tcctcagagg 960 acagtttttt tgttgttgtg tttttttgtt tttttttttt ggtagatgca tgacttgtgt 1020 gtgatgagag aatggagaca gagtccctgg ctcctctact gtttaacaac atggctttct 1080 tattttgttt gaattgttaa ttcacagaat agcacaaact acaattaaaa ctaagcacaa 1140 agccattcta agtcattggg gaaacggggt gaacttcagg tggatgagga gacagaatag 1200 agtgatagga agcgtctggc agatactcct tttgccactg ctgtgtgatt agacaggccc 1260 agtgagccgc ggggcacatg ctggccgctc ctccctcaga aaaaggcagt ggcctaaatc 1320 ctttttaaat gacttggctc gatgctgtgg gggactggct gggctgctgc aggccgtgtg 1380 tctgtcagcc caaccttcac atctgtcacg ttctccacac gggggagaga cgcagtccgc 1440 ccaggtcccc gctttctttg gaggcagcag ctcccgcagg gctgaagtct ggcgtaagat 1500 gatggatttg attcgccctc ctccctgtca tagagctgca gggtggattg ttacagcttc 1560 gctggaaacc tctggaggtc atctcggctg ttcctgagaa ataaaaagcc tgtcatttc 1619 <210> 446 <211> 275 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(275) <223> N=any base <400> 446 gcttgtatat aagattactt tattcctgca tcttctcaat gggttcttcc ttgtatttgc 60 ccttttcctt tccnacttgg cgagatttgg ctttccgttc gaggatcttt ttgcgggctt 120 tgtccagttt tagcctagng anaaccacct tgctggggng aatgcctacg ngganagttg 180 tgccattagc cttttcccgn tgcanccgtt caatgtagat aacatatttc ttccngtaaa 240 cctgggctac tttgccaatt tgctgaccnt tatag 275 <210> 447 <211> 389 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(389) <223> N=any base <400> 447 ttctcctcgg ccaattcgcg gaagaagtgg ctcacgcctt ccagagccac atcatcgcgg 60 tcgaaataga agcccagaga gaggtaggtg taggaggcct gcaggtacaa attgaccagg 120 ctgttgacgg ctgcctccac gtcggtgaat aattctgacg aatctgggag ctcatggttg 180 gttggcaaga aggagctaac cacaaaaacg gtgctggcag gtcccagaag caggagatgg 240 ccgagaagat ggtcccggag ttgcaagcgg agaggaaatc ggagggcggt cggaggctgg 300 aagagagtcc ccggatctgt tccgtccaaa cactttttga agcaagagac agacccgcgg 360 gaccncctag tgccgaattn ttggcttcg 389 <210> 448 <211> 443 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(443) <223> N=any base <400> 448 gccagggctc agtgggcaag ggctctgtgc cgtngncctg tacgactacc atgcagccga 60 cgacacagag atctcctttg accccgagaa cctcatcacg ggcatcgagg tgatcgacga 120 aggctggtgg cgtggctatg ggccggatca tntgttngca tgttccctgc caactacgtg 180 gagctcattg agtgaggctg agggcacatc ttgcccttcc cctctcagac atggcttcct 240 tattgctgga agaggaggcc tggggagttg acattcagca ctcttccagg gaatagggac 300 ccccagttga ggattgaggc ntcagggttc cctccggntt gggcagattc agccttttca 360 ccccaaatgg cagcaattgg cntgggtgat ttcccacaaa tcnttcctgg cattcccccg 420 acctttccca gacagtttgg ttt 443 <210> 449 <211> 636 <212> DNA <213> HUMAN <400> 449 accatggccc cctttgagcc cctggcttct ggcatcctgt tgttgctgtg gctgatagcc 60 cccagcaggg cctgcacctg tgtcccaccc cacccacaga cggccttctg caattccgac 120 ctcgtcatca gggccaagtt cgtggggaca ccagaagtca accagaccac cttataccag 180 cgttatgaga tcaagatgac caagatgtat aaagggttcc aagccttagg ggatgccgct 240 gacatccggt tcgtctacac ccccgccatg gagagtgtct gcggatactt ccacaggtcc 300 cacaaccgca gcgaggagtt tctcattgct ggaaaactgc aggatggact cttgcacatc 360 actacctgca gttttgtggc tccctggaac agcctgagct tagctcagcg ccggggcttc 420 accaagacct acactgttgg ctgtgaggaa tgcacagtgt ttccctgttt atccatcccc 480 tgcaaactgc agagtggcac tcattgcttg tggacggacc agctcctcca aggctctgaa 540 aagggcttcc agtcccgtca ccttgcctgc ctgcctcggg agccagggct gtgcacctgg 600 cagtccctgc ggtcccagat agcctgaatc ctgccc 636 <210> 450 <211> 46 <212> DNA <213> HUMAN <400> 450 gtttattcat ctgtttatga cacagtacac aggaggcaaa gtgttt 46 <210> 451 <211> 250 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(250) <223> N=any base <400> 451 natccatcag ctcgttcaac tttagcacct gtctcgnccc cagtggcttt tccagaacta 60 ctgccttcac catgaagcnc catgagcttn cccaattcaa acttgggctn cttcagcatt 120 tttacttgnc taacgaagac ancanggaga gganaaatag antggcaagc cttnncaang 180 nctntaccaa tgctgnctgg aancaannna nngaccacnn cnnacaagnc aatagtctgn 240 accncncggg 250 <210> 452 <211> 367 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(367) <223> N=any base <400> 452 tccaaagaat ttattatcaa aactaaaaca aaacttcagt tgtacataaa gtaataaact 60 ttacaacagc tgttaagaga aagtcgtgat gtaagtttat acatattacc gaagcaaaga 120 ggacaagcaa aggagagctc cagttggaat gttgattaca ttcatgcagc ttcctcttga 180 tttaaacact catgacacat tgaatgaaat catcatatgg gaaattcaca acaccttgct 240 gagcagtatc ccgtcttcga aagctgtctg taagngccct cagtttgacg cagcaggngn 300 tgtagtcgtc gaaggtgatc tttccattgg ngctgtatcg ttttgcaatt ggnttcacag 360 cctgggg 367 <210> 453 <211> 3063 <212> DNA <213> HUMAN <400> 453 ggcacgagtg gctgcttgcg gctagtggat ggtaattgcc tgcctcgcgc tagcagcaag 60 ctgctctgtt aaaagcgaaa atgaaacaat tgcctgcggc aacagttcga ctcctttcaa 120 gttctcagat catcacttcg gtggtcagtg ttgtaaaaga gcttattgaa aactccttgg 180 atgctggtgc cacaagcgta gatgttaaac tggagaacta tggatttgat aaaattgagg 240 tgcgagataa cggggagggt atcaaggctg ttgatgcacc tgtaatggca atgaagtact 300 acacctcaaa aataaatagt catgaagatc ttgaaaattt gacaacttac ggttttcgtg 360 gagaagcctt ggggtcaatt tgttgtatag ctgaggtttt aattacaaca agaacggctg 420 ctgataattt tagcacccag tatgttttag atggcagtgg ccacatactt tctcagaaac 480 cttcacatct tggtcaaggt acaactgtaa ctgctttaag attatttaag aatctacctg 540 taagaaagca gttttactca actgcaaaaa aatgtaaaga tgaaataaaa aagatccaag 600 atctcctcat gagctttggt atccttaaac ctgacttaag gattgtcttt gtacataaca 660 aggcagttat ttggcagaaa agcagagtat cagatcacaa gatggctctc atgtcagttc 720 tggggactgc tgttatgaac aatatggaat cctttcagta ccactctgaa gaatctcaga 780 tttatctcag tggatttctt ccaaagtgtg atgcagacca ctctttcact agtctttcaa 840 caccagaaag aagtttcatc ttcataaaca gtcgaccagt acatcaaaaa gatatcttaa 900 agttaatccg acatcattac aatctgaaat gcctaaagga atctactcgt ttgtatcctg 960 ttttctttct gaaaatcgat gttcctacag ctgatgttga tgtaaattta acaccagata 1020 aaagccaagt attattacaa aataaggaat ctgttttaat tgctcttgaa aatctgatga 1080 cgacttgtta tggaccatta cctagtacaa attcttatga aaataataaa acagatgttt 1140 ccgcagctga catcgttctt agtaaaacag cagaaacaga tgtgcttttt aataaagtgg 1200 aatcatctgg aaagaattat tcaaatgttg atacttcagt cattccattc caaaatgata 1260 tgcataatga tgaatctgga aaaaacactg atgattgttt aaatcaccag ataagtattg 1320 gtgactttgg ttatggtcat tgtagtagtg aaatttctaa cattgataaa aacactaaga 1380 atgcatttca ggacatttca atgagtaatg tatcatggga gaactctcag acggaatata 1440 gtaaaacttg ttttataagt tccgttaagc acacccagtc agaaaatggc aataaagacc 1500 atatagatga gagtggggaa aatgaggaag aagcaggtct tgaaaactct tcggaaattt 1560 ctgcagatga gtggagcagg ggaaatatac ttaaaaattc agtgggagag aatattgaac 1620 ctgtgaaaat tttagtgcct gaaaaaagtt taccatgtaa agtaagtaat aataattatc 1680 caatccctga acaaatgaat cttaatgaag attcatgtaa caaaaaatca aatgtaatag 1740 ataataaatc tggaaaagtt acagcttatg atttacttag caatcgagta atcaagaaac 1800 ccatgtcagc aagtgctctt tttgttcaag atcatcgtcc tcagtttctc atagaaaatc 1860 ctaagactag tttagaggat gcaacactac aaattgaaga actgtggaag acattgagtg 1920 aagaggaaaa actgaaatat gaagagaagg ctactaaaga cttggaacga tacaatagtc 1980 aaatgaagag agccattgaa caggagtcac aaatgtcact aaaagatggc agaaaaaaga 2040 taaaacccac cagcgcatgg aatttggccc agaagcacaa gttaaaaacc tcattatcta 2100 atcaaccaaa acttgatgaa ctccttcagt cccaaattga aaaaagaagg agtcaaaata 2160 ttaaaatggt acagatcccc ttttctatga aaaacttaaa aataaatttt aagaaacaaa 2220 acaaagttga cttagaagag aaggatgaac cttgcttgat ccacaatctc aggtttcctg 2280 atgcatggct aatgacatcc aaaacagagg taatgttatt aaatccatat agagtagaag 2340 aagccctgct atttaaaaga cttcttgaga atcataaact tcctgcagag ccactggaaa 2400 agccaattat gttaacagag agtcttttta atggatctca ttatttagac gttttatata 2460 aaatgacagc agatgaccaa agatacagtg gatcaactta cctgtctgat cctcgtctta 2520 cagcgaatgg tttcaagata aaattgatac caggagtttc aattactgaa aattacttgg 2580 aaatagaagg aatggctaat tgtctcccat tctatggagt agcagattta aaagaaattc 2640 ttaatgctat attaaacaga aatgcaaagg aagtttatga atgtagacct cgcaaagtga 2700 taagttattt agagggagaa gcagtgcgtc tatccagaca attacccatg tacttatcaa 2760 aagaggacat ccaagacatt atctacagaa tgaagcacca gtttggaaat gaaattaaag 2820 agtgtgttca tggtcgccca ttttttcatc atttaaccta tcttccagaa actacatgat 2880 taaatatgtt taagaagatt agttaccatt gaaattggtt ctgtcataaa acagcatgag 2940 tctggtttta aattatcttt gtattatgtg tcacatggtt attttttaaa tgaggattca 3000 ctgacttgtt tttatattga aaaaagttcc acgtattgta gaaaacgtaa ataaactaat 3060 aac 3063 <210> 454 <211> 1911 <212> DNA <213> HUMAN <400> 454 gaattcccct gtgttagacg gtacaggtgg aagaagactg ctgtgtgcag gaggaatttg 60 cagtgagact tcaaggaaga gaataagctc gccacataaa gaggaaacaa agagcaaccc 120 agagttcaga cccaggaagc ggccgggagg gcaggagcga atcgggccgc cgccgccatg 180 gagctgagag tcgggaacag gtaccggctg ggccggaaga tcggcagcgg ctccttcgga 240 gacatctatc tcggtacgga cattgctgca ggagaagagg ttgccatcaa gcttgaatgt 300 gtcaaaacca aacaccctca gctccacatt gagagcaaaa tctacaagat gatgcaggga 360 ggagtgggca tccccaccat cagatggtgt ggggcagagg gggactacaa cgtcatggtg 420 atggagctgc tggggccaag cctggaggac ctcttcaact tctgctccag gaaattcagc 480 ctcaaaaccg tcctgctgct tgctgaccaa atgatcagtc gcatcgaata cattcattca 540 aagaacttca tccaccggga tgtgaagcca gacaacttcc tcatgggcct ggggaagaag 600 ggcaacctgg tgtacatcat cgacttcggg ctggccaaga agtaccggga tgcacgcacc 660 caccagcaca tcccctatcg tgagaacaag aacctcacgg ggacggcgcg gtacgcctcc 720 atcaacacgc accttggaat tgaacaatcc cgaagagatg acttggagtc tctgggctac 780 gtgctaatgt acttcaacct gggctctctc ccctggcagg ggctgaaggc tgccaccaag 840 agacagaaat acgaaaggat tagcgagaag aaaatgtcca cccccattga agtgttgtgt 900 aaaggctacc cttccgaatt tgccacatac ctgaatttct gccgttcctt gcgttttgac 960 gacaagcctg actactcgta cctgcggcag cttttccgga atctgttcca tcgccagggc 1020 ttctcctatg actacgtgtt cgactggaac atgcttaaat ttggtgccag ccgggccgcc 1080 gatgacgccg agcgggagcg cagggaccga gaggagcggc tgagacactc gcggaacccg 1140 gctacccgcg gcctcccttc cacagactcc ggccggctgc gggggacgca ggaagtggct 1200 ccccccacac ccctcacccc tacctcacac acggctaaca cctccccccg gcccgtctcc 1260 ggcatggaga gagaacggaa agtgagtatg cggctgcacc gcggggcccc cgtcaacatc 1320 tcctcgtccg acctcacagg ccgacaagat acctctcgca tgtccacctc acagattcct 1380 ggtcgggtgg cttccagtgg tcttcagtct gtcgtgcacc gatgagaact ctccttattg 1440 ctgtgaaggg cagacaatgc atggctgatc tactctgtta ccaatggctt tacctagtga 1500 cacgtccccc ggtctaggat cgaaatgtta acaccgggag ctctccaggc cactcaccca 1560 gcgacgctcg tgggggaaac atactaaacg gacagactcc aagagctgcc accgctgggg 1620 ctgcactgcg gccccccacg tgaactcggt tgtaacgggg ctgggaagaa aagcagagag 1680 agaattgcag agaatcagac tccttttcca gggcctcagc tccctccagt ggtggccgcc 1740 ctgtactccc tgacgattcc actgtaacta ccaatcttct acttggttaa gacagttttg 1800 tatcattttg ctaaaaatta ttggcttaaa tctgtgtaaa gaaaatctgt ctttttattg 1860 tttcttgtct gtttttgcag tcttacaaaa aaaatgttga ctaaggaatt c 1911 <210> 455 <211> 628 <212> DNA <213> HUMAN <400> 455 tcgggagccg cggcttatgg tgcagacatg gccaagtcca agaaccacac cacacacaac 60 cagtcccgaa aatggcacag aaatggtatc aagaaacccc gatcacaaag atacgaatct 120 cttaaggggg tggaccccaa gttcttgagg aacatgcgct ttgccaagaa gcacaacaaa 180 aagggcctaa agaagatgca ggccaacaat gccaaggcca tgagtgcacg tgccgaggct 240 atcaaggccc tcgtaaagcc caaggaggtt aagcccaaga tcccaaaggg tgtcagccgc 300 aagctcgatc gacttgccta cattgcccac cccaagcttg ggaagcgtgc tcgtgcccgt 360 attgccaagg ggctcaggct gtgccggcca aaggccaagg ccaaggccaa ggccaaggat 420 caaaccaagg cccaggctgc agccccagct tcagttccag ctcaggctcc caaacgtacc 480 caggccccta caaaggcttc agagtagata tctctgccaa catgaggaca gaaggactgg 540 tgcgaccccc cacccccgcc cctgggctac catctgcatg gggctggggt cctcctgtgc 600 tatttgtaca aataaacctg aggcagga 628 <210> 456 <211> 274 <212> DNA <213> HUMAN <400> 456 acccctgaag ctctccaagg ccgtgcataa ggctgtgctg accatcgacg agaaagggac 60 tgaagctgct ggggccatgt ttttagaggc catacccatg tctatccccc ccgaggtcaa 120 gttcaacaaa ccctttgtct tcttaatgat tgaacaaaat accaagtctc ccctcttcat 180 gggaaaagtg gtgaatccca cccaaaaata actgcctctc gctcctcaac ccctcccctc 240 catccctggc cccctccctg gatgacatta aaga 274 <210> 457 <211> 2166 <212> DNA <213> HUMAN <400> 457 cggcccggcc atggcggccc cccgcccgtc tcccgcgatc tccgtttcgg tctcggctcc 60 ggctttttac gccccgcaga agaagttcgg ccctgtggtg gccccaaagc ccaaagtgaa 120 tcccttccgg cccggggaca gcgagcctcc cccggcaccc ggggcccagc gcgcacagat 180 gggccgggtg ggcgagattc ccccgccgcc cccggaagac tttcccctgc ctccacctcc 240 ccttgctggg gatggcgacg atgcagaggg tgctctggga ggtgccttcc cgccgccccc 300 tcccccgatc gaggaatcat ttccccctgc gcctctggag gaggagatct tcccttcccc 360 gccgcctcct ccggaggagg agggagggcc tgaggccccc ataccgcccc caccacagcc 420 cagggagaag gtgagcagta ttgatttgga gatcgactct ctgtcctcac tgctggatga 480 catgaccaag aatgatcctt tcaaagcccg ggtgtcatct ggatatgtgc ccccaccagt 540 ggccactcca ttcagttcca agtccagtac caagcctgca gccgggggca cagcacccct 600 gcctccttgg aagtcccctt ccagctccca gcctctgccc caggttccgg ctccggctca 660 gagccagaca cagttccatg ttcagcccca gccccagccc aagcctcagg tccaactcca 720 tgtccagtcc cagacccagc ctgtgtcttt ggctaacacc cagccccgag ggcccccagc 780 ctcatctccg gctccagccc ctaagttttc tccagtgact cctaagttta ctcctgtggc 840 ttccaagttc agtcctggag ccccaggtgg atctgggtca caaccaaatc aaaaattggg 900 gcaccccgaa gctctttctg ctggcacagg ctcccctcaa cctcccagct tcacctatgc 960 ccagcagagg gagaagcccc gagtgcagga gaagcagcac cccgtgcccc caccggctca 1020 gaaccaaaac caggtgcgct cccctggggc cccagggccc ctgactctga aggaggtgga 1080 ggagctggag cagctgaccc agcagctaat gcaggacatg gagcatcctc agaggcagaa 1140 tgtggctgtc aacgaactct gcggccgatg ccatcaaccc ctggcccggg cgcagccagc 1200 cgtccgcgct ctagggcagc tgttccacat cgcctgcttc acctgccacc agtgtgcgca 1260 gcagctccag ggccagcagt tctacagtct ggagggggcg ccgtactgcg agggctgtta 1320 cactgacacc ctggagaagt gtaacacctg cggggagccc atcactgacc gcatgctgag 1380 ggccacgggc aaggcctatc acccgcactg cttcacctgt gtggtctgcg cccgccccct 1440 ggagggcacc tccttcatcg tggaccaggc caaccggccc cactgtgtcc ccgactacca 1500 caagcagtac gccccgaggt gctccgtctg ctctgagccc atcatgcctg agcctggccg 1560 agatgagact gtgcgagtgg tcgccctgga caagaacttc cacatgaagt gttacaagtg 1620 tgaggactgc gggaagcccc tgtcgattga ggcagatgac aatggctgct tccccctgga 1680 cggtcacgtg ctctgtcgga agtgccacac tgctagagcc cagacctgag tgaggacagg 1740 ccctcttcag accgcagtcc atgccccatt gtggaccacc cacactgaga ccacctgcgc 1800 ccacctcagt tattgttttg atgtctagcc cctcccattt ccaacccctc cctagcatcc 1860 caggtgccct gacccaggac ccaacatggt ctagggatgc aggatccccg ccctggggtc 1920 tggtcctcgc ccatcctgca gggattgccc accgtcttcc agacacccca cctgaggggg 1980 gcaccaggtt tagtgctgct gctttcactg ctgcacccgc gccctcggcc ggccccccga 2040 gcagcctttg tactctgctt gcggagggct gggagaccct ccaggacatt cccaccctcc 2100 cccatgctgc caagttgtag ctatagctac aaataaaaaa aaaccttgtt ttccaaaaaa 2160 aaaaaa 2166 <210> 458 <211> 2966 <212> DNA <213> HUMAN <400> 458 gcacgctgaa ggagccggcg gaaccgggtg gccatgggga tgtgggcatc gctggacgct 60 ttgtgggaga tgccggccga gaagcgtatc ttcggggccg tgctgctctt ttcctggaca 120 gtgtatcttt gggagacctt cctagcacag cggcagagaa ggatatataa aacaacaact 180 catgtaccac cggagttagg acagatcatg gattctgaaa catttgagaa atctcgactc 240 tatcaactgg ataaaagcac tttcagcttc tggtcaggac tctattcaga gactgaaggc 300 actcttattc ttctctttgg aggaatacct tatctctgga gactttctgg acggttctgt 360 ggttatgctg gctttggacc agaatatgag atcactcagt ccctggtgtt tctgctgttg 420 gctacacttt tcagtgcatt gactggtttg ccatggagtc tttataatac ttttgtgata 480 gaagaaaaac atggcttcaa tcaacagact ttggggttct tcatgaaaga tgcaatcaag 540 aaatttgttg tgactcagtg tattttgttg cctgtgtctt cacttctact ttacattatt 600 aaaattgggg gtgactattt ttttatttat gcctggctgt tcacattagt tgtgtctctg 660 gttcttgtca caatctatgc tgattatatt gcccctttat ttgacaaatt cacacctctg 720 cctgagggaa agcttaaaga agaaattgaa gtaatggcaa agagtattga ctttcctttg 780 acgaaggtgt atgttgtgga aggatctaaa cgctcttccc acagcaatgc ttatttttat 840 ggcttcttca agaacaagcg aatagttttg tttgacactc tactagaaga gtactctgta 900 ctaaacaaag acatccagga ggattctggc atggaacccc gcaatgagga agaagggaac 960 agtgaagaaa taaaagctaa agttaaaaat aagaaacaag gatgtaaaaa tgaggaggta 1020 ctcgctgtac taggccatga actggggcac tggaagttgg gacatacagt caaaaatatc 1080 attattagcc agatgaattc tttcctgtgt ttttttttat ttgctgtatt aattggtcga 1140 aaggagcttt ttgctgcatt tggtttttat gatagccaac ccactcttat tggactattg 1200 atcatcttcc agtttatttt ttcaccttac aatgaggttc tttctttttg cctaacagtc 1260 ctaagccgca gatttgagtt tcaagctgat gcatttgcca agaaacttgg gaaggctaaa 1320 gacttatatt ctgctttaat caaacttaac aaagataact tgggattccc tgtttctgac 1380 tggttgttct caatgtggca ttattctcat cctccactgc tagagagact tcaagctttg 1440 aaaactatga agcaacactg agatgtccag gatctgtgac tgaagacatt tctgattatt 1500 tctgtcctgg gcagcatgtt ccagctcttg atgtttttaa actttttttt agaagaaaaa 1560 ttaagtacag aaaagcccag atttaaatac atttaatatg tcattttaaa aatgatttta 1620 ataattcatt tcttaaaaca ctgaatgaat tttgaagctt aatgttttta aaggcatagt 1680 tttatctttg acatctaatt taccatcaag ttgtaaaatt atttggaaaa atacagaact 1740 cgttttattt gtatacttat atggaatctg catgtgaggt gtttgagggc atatgtttga 1800 aagagggagc atcaccacag gaatccttct gtgaggtgga aacagtggtc ctgaatcatt 1860 gtgctcacac ctaacttgaa atctggtctt actttcatgc tgttatgatt tcacctggtg 1920 aatcagtgtt ttaaataaga aaggtaatag ttggtaaggc caatgttatt taaatgaaag 1980 tagttagaaa aatgctctcc tattctacca aatttttaat ttctttcttc ccctttcttg 2040 ctacacagtg atcaagagtt tctcatagtg ctttgaagtt agaaattatg tataggatat 2100 tttaaatcat tgagttttgt ggggtttttt tgtttgtttg tttcttttgt tttttggaaa 2160 atccgtgtct ttatcttttt ttcccacgtg gtagatatga tcccattgga ggtaaattgt 2220 agcttcttct cattcatgca gtaaataata catcctttca ctcagcagag atggccatat 2280 taaacacgtt ttgctatgtt aaaagtggca gaacaggaaa gacgaattaa aaataacatt 2340 ttttaagcga cataaggatg aaatactgat gaatctctgt gacattacag ggaaaaaaat 2400 atagttttct atctctttca agggcagaag agttttcatt tttatttttg taattttatc 2460 tgtaagtcat aaatattact taatcaggcc tgattctact tttgaaaatt acagttcttg 2520 aaatgcagat aatgtttact ttgaaaacaa atgtcatgaa tgatttccag tttttaaagc 2580 tatatgtttc actgcttcat atctctgtcc actttctgaa tgagaactta ttttgtgcct 2640 agagctctca ctcactgata atgcttatta ccttctgggc atttattcca aagtgggatc 2700 aactgtacgc ctttggtatc tgaccataaa gtctttcctc cgctgacatt tgggtgatgt 2760 cttcacatgg aaatataata aaaataaaaa tctagtttaa tactgcatta tttattttcc 2820 taaggctaaa gaggagcagt cctatgcttt tattcagcat cctttatctg tgacttcatg 2880 ctctgataac tgcctttcct tccttctgtg cctttgaata caaatttcag ttctgcaaaa 2940 gtgaaacatt aaacattgcc aacgca 2966 <210> 459 <211> 490 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(490) <223> N=any base <400> 459 agaaaatccc taagacagat cttgccgtgg actagcanta cctgcaagtg ctgccaatgg 60 gaactcaatt tattcctggg aacctaacga ggagagccca ggcctaggca ggaggctgga 120 accctcttgg ctaaggtgct gttcctgttc ctgcaaggtc tccagaaccc ctttggaaat 180 ggtgaaggaa ccagcccaat agaagtacag agccagctga caagtccttg taaagctcac 240 tcctcagtcc ttggcacagc atgttttgtc ttctctcttg gtatttcttc tctcccaact 300 ttaagccatt ttgccttgga atcatgatta caattttttc ctttgcagat gccttcctgg 360 gggatactcc tccccaccct aaagggtcgc ctgcaactta ggcggattgg gtctctctgc 420 tgtggcgttc tctcttgaga gaccctctga attttagcac aaagtggctt ctgtttcaca 480 gctgccacca 490 <210> 460 <211> 551 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(551) <223> N=any base <400> 460 gtcactctgc tgcggcacag acctgaatta acaactctag ctagggctga cttcaaaaag 60 cactttcgtt ttttaataac caacatcagc tcagcaggct tcatttggga aaagaaacct 120 tgtcggatta ccccgacatt ctccacctcc tgggaggcca gccattccca aatgccccaa 180 ggatcgaaga acggagacgg taagatgatt aattgcactg caggtttttt gtttctgtat 240 ttttttccct cctttttttg ggtttacttt cacattaatg aggtatttag gaaagacaaa 300 tggaatctga taaaaggtaa cgttatattg tttgtcgaaa caacatttta aggatttctt 360 gaagttatat ggctctgtag gcatgtttca ctttaagatg tgtttctgan gtcatattag 420 gagaacgact ggtgattatc tatgggaaga ttaactatga aaccatatgg gaaatatcct 480 taatacctgt aatatacctt ataaccctga atagttacat gacttttggg aagtggtnag 540 agaattgtat t 551 <210> 461 <211> 277 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(277) <223> N=any base <400> 461 gtaatggggt ccctcctntc ctgccttttc tggactgagg aaaatttccc atgaagacag 60 taaccaggaa aaattcagcc acaactattt ttcctatctc ctgatgcttg aagatcggtg 120 ttacatattt gtcctactag gaaaccctac ataatttatt cattcaacaa atacttatta 180 gagtacctct atgatctgga cagtcttcca aggcattggt ggacaaaatg gacaaaagtc 240 tcttgcacct catgcaactc acatgcntat aaaagta 277 <210> 462 <211> 535 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(535) <223> N=any base <400> 462 tttgccggag atgtggtggt acagtgggag ctattctgac atgtccactg gaagttgtaa 60 aaacacgact gcagtcatct tctgtgacgc tttatatttc tgaagttcag ctgaacacca 120 tggctggagc agtgtcaacc gagtagtgtc tcccggacct cttcattgcc taaaggtgat 180 cttggaaaaa gaagggcctc gttccttgtt tagaggacta ggccccaatt tagtgggggt 240 agcccttcca gagcaatata ctttgctgct tattcaaact gcaaggaaaa gttgaatgat 300 gtatttgatc ctgattctac ccaagtacat atgatttcag ctgcaatggc aggttttact 360 gcaatcacag caaccaaccc catttggctt ataaagactc ggttacagct ttgatgcaag 420 gaaccgcggg gaaaggcgaa tgggtgcttt tgaatgtgtt ccgtaagtgt atcagacaga 480 tggactaaaa nggttttata ggggcatgtc tgcctcatat gctggtatat cagan 535 <210> 463 <211> 406 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(406) <223> N=any base <400> 463 ggaaggtcag agaacaccaa acagatttaa cccaaataag atttccctaa ggcatacaat 60 aatcaaactc tcaaagttca aggacaaagg gaattctaat accagcaaga gaaaagaagc 120 aaataatata taaaggagtt ccaattcatt tgtcaatnac attctcaaca gaaaccattc 180 agaactagat ggagtgcaat gacattttca aagtgctgaa agagaaaaca cttccataca 240 agaatactct atatagcaaa gttatccttc aggtacgaag gagagataaa gactttccca 300 aacaaaagct gagagaattc actagcacca ggccagtctt acaagaaatg ctaaagagag 360 tttttctatt tgaatgaaaa anaaaaacac taataggaaa agaact 406 <210> 464 <211> 577 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(577) <223> N=any base <400> 464 atgattcctc ttgattcttt tgttggccag agtgctgatg gcaaaatggt tcctataatc 60 cctggtggaa atagtatccc actcacattt tccaacagga aggaatatgt ggagagggcc 120 attgaatatc gacttcatga gatggacaga caggtggctg cagtccgaga agggatgtcc 180 tggattgttc ctgtgccgct gctgtccctc ctcacagcaa aacaactgga gcagatggtg 240 tgtgggatgc ccgagatctc tgtggaagtc ttgaagaaag tggtgcggta ccgtgagtgg 300 atgagcagca tcagctggtg cagtggttct ggcacacgct ggaagagttc tccaatgagg 360 agcgggtgct tttcatgagg tttgtgtcag gaagatctcg actaccagcc aacactgctg 420 acatttctca gagatttcaa atcatgaagg ttgataggcc ttacgacagt ctgcctacct 480 cacagacctg cttcttccag ctgaagctgc cccccgtact cccagccagc tggtcatggc 540 cgagcgcctg cctaattgcn aatcaacaac tgccgct 577 <210> 465 <211> 457 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(457) <223> N=any base <400> 465 cgagattgtg ccactcgatc cagcctgggc gacagagcga gactctgctc aagaaaaaaa 60 aaaaaaaaga aaataaaaaa aagattttga taaattgata ccaacaggag gcattgtagt 120 aaggtggaaa gaacattgga ttgggagtta ggagagtcag gttctgatgc tggttctgcc 180 accactcact ttgttgttgg ttgattaatt ttaatttatg ttttgagaca gcgtctcact 240 cccgtcgccc aggctgcgag tgncgtacgg tgttcacagc tcactgcaga ttcaacttgg 300 gttcaggtga ttcttccact tcagcctccc aagtagctgg gactacagga gtgcaccacc 360 acgcccagct aattttttgt attttagcag agacaaggtt tcaccatgtt gcccaggctg 420 atctcgaact cctgagctca ggtgatctgc ctgcctt 457 <210> 466 <211> 647 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(647) <223> N=any base <400> 466 caaatgggga gcctgcgcct tgtgttggca ggcaatgcag tcattttcct tacaattcaa 60 gggtttttcc ttatatttgg aagaggagat gattttagct gggagcagtg gtagcacttt 120 attctgatta cagtgcattg aatttcttag aactcatact atctgtatac atgtgcacat 180 gcggcatttt actatgaaat ttaatatgct gggtttttta atacctttat atatcatgtt 240 cactttaaga aagacttcat aagtaggaga tgagttttat tctcagcaaa tagacctgtc 300 aaatttagat tatgttactc aaattatgtt acttgtttgg ctgttcatgt agtcacggtg 360 ctctcagaaa atatattaac acagtcttgt aggcagctgc caccttatgc agtgcatcga 420 aaccttttgc ttggggatgt gcttggagag gcagataacg ctgaagcagg cctctcatga 480 cccaggaagg ccggggtgga tcccttttgt gttgtagtcc atgcattaaa agtgtggccc 540 acagaccaag agcctcaaca tttcctagag ccttattaga aatgcagaat ctgaagccca 600 ctctggaccc aggacatttg atgagatcca angagttgta tgcncat 647 <210> 467 <211> 479 <212> DNA <213> HUMAN <400> 467 ctgagattag ttcagatggt ctaaccattg ttctatatgt gcattttagt taatattgtg 60 tattaaagga taagtcttaa tgctcaaagt atgttaaaaa tagatgtagt aaatcagtcc 120 ctttgtgaat gtccttttgt tagtttttag gaaggcctgt cctctgggag tgacctttat 180 tagtccaccc cttggagcta gacatcctgt acttagtcac ggggatggtg gaagagggag 240 aagaggaagg gtgaagggaa gggctctttg ctagtatctc catatctaga cgatggtttt 300 agatgataac cacaggtcta caagagcgtt tttagtaaag tgcctgtgtt cattgtggac 360 aaagttatta ttttgcaaca tctaagcttt acgaatgggg tgacaactta tgataaaaac 420 tagagctagt gaattagcct atttgtaaat acctttgtta taattgatag gatacatct 479 <210> 468 <211> 308 <212> DNA <213> HUMAN <400> 468 ctgtcaagct gttctttatt tcagggagag ggcaggggag tgtttgattt cggggtagga 60 atgtttctgg ttggagggcg ctttatctca gggttggaat gtttctgatt ggaggtgtca 120 tttgtggttt atggtcatgc tgacagccat taggctgatt ttttgggggc tggatttagg 180 cggtttttaa tcaaggggaa cttaaaatgc tgctgtttgt ccaaaatgtt gatgctcctg 240 ctttgtcaat ccagacccta tagttataaa aggatgaggg gcgacgtgct ctttctggct 300 acttcctg 308 <210> 469 <211> 588 <212> DNA <213> HUMAN <400> 469 cagatactgt gctgagtgta ataggctgca tcctgctgag gaaggagact tttgggcaga 60 gtcaagcatg ttgggcctca agatcaccta ctttgcactg atggatggaa aggtgtatga 120 catcacagag tgggctggat gcagcgtgta ggtatctccc cagataccca cagagtcccc 180 tatcacatct catttggttc tcggattcca ggcaccagag ggcggcagag agccacccca 240 gatgcccctc ctgctgatct tcaggatttc ttgagtcgga tctttcaagt acccccaggg 300 cagatgccaa tgggaacttc tttgcagctc ctcagcctgc ccctggagcc gctgcagcct 360 ctaagcccaa cagcacagta cccaagggag aagccaaacc taagcggcgg aagaaagtga 420 ggaggccctt ccaacgttga tgccccttct ctttcctcaa atcaatgtca gggagtcaaa 480 agggctgtag cacaggatgg agtttgattt atccctcctc ccccaacacc taggaactga 540 atctttttct ttttattttt tgagatggag tcttgctctg ttgcccag 588 <210> 470 <211> 533 <212> DNA <213> HUMAN <400> 470 tctatacgga atattaaaca cattactgat atcccatata attctgaagg acaagccata 60 gtggaaagaa tgaatctctc cctgaaacag cagttgcaga agcaaaaggg ggaaaacagg 120 tactacagga caccccataa gcaattgaat cgcattatta actttaaatt ttttgagcct 180 gcctaaaggc cggatcttat cagcagctga acagcatcta cagaaaccag ctgcaaagac 240 agaagcagaa caactggttt ggtggagaga cctgataaca gaaagttggg aaataggtaa 300 aataataact tggggtagag gttatgctta tgtttctcca ggactgaacc atcaagacac 360 ctgaaacctt atcatgagcg aatgctgagg aagagattcc gggagatccc gaggaccccc 420 ccagctgcag ccatgtcaag actgatgctg aggaggaccc caactgtcac gagcaacacc 480 cgtcaaacac agccacccac ctgaggtcag atcaagaagc tgtcacagat ggc 533 <210> 471 <211> 402 <212> DNA <213> HUMAN <400> 471 tgtacggaga agaccttcaa ttatcattac aggatttaaa tttaccctgg cttttaaagg 60 aatagggcac actttttttt tttttttttt ttactatttc tttttctttc ttttgctctt 120 tgactccctc tttgtctctc tctctgtctc tttctctctc tgactctctc tctctctcct 180 tctctctctc tctccgtgtc tctctcttag ccattacaaa cttggggccc tggcaagggt 240 gagtggggaa tgggtcccac ataactgccc attcgagagt tatataccta aattgggaga 300 gacaccaggg ataagactcc ctgggttata acctaggtgc ctaaggacac aacacagagc 360 ttccttagat tcctttggag atacaacttg ctagaggaaa tg 402 <210> 472 <211> 430 <212> DNA <213> HUMAN <400> 472 gtcgacggac acagtgggga aacccagcaa ggccactgtg cacaattccc cttcccctga 60 ggatagggca ggacccctcg ggaatgaggg tcttccaggg aggagggagt gaccttgcta 120 ggttttatgg ctggctttgg gagagaggag ttctagtttc tatgacctgc tgtgagaaaa 180 agaattgtgg tttctgggac tcactttgcg gcagaaaagt aggcaggaac caggagggaa 240 ggacaaagac ctggcttctg aggccttcca gtctcctctg ggtcagagta gtctgcatgc 300 caaggtgcca tactttcggg gtttaatgag ccctgacagc aggtccttgc agatttcaca 360 ggcaacttgt gatcccagta attgggtttc agtcccccaa tttcagagga ctttagcaaa 420 gcctggttga 430 <210> 473 <211> 561 <212> DNA <213> HUMAN <400> 473 tttttttttc acaagactag atggagaatt aatgaagaag aaatagaaat gaggcttatt 60 taaggtacaa aattcttgta tttgtaataa cctagattta tagatataaa acaagtcttt 120 taaagacttc cctaaaatac tcaatataaa acaggagtta cttatcctag atcatcctta 180 gttaggtaca catgattctc tgtgcaacta gctggtggac atgaataaaa gctgctgggc 240 ctataatgta ctaaaacatt tttctccctt cagcaagaca ggtagggttg aaggctaaat 300 gcatcagagg agtattttct taggcatttt ggacaatctt tttgcagtag gttccatagg 360 ttttccccag cgaaagttga ctcagaccag agtaactctg acacaagttg ccaagaggga 420 aaaaatactt catttgctag attacccaaa tgtgtagcct catttaatta ccaaggtaag 480 aatcatcccc aaccactttt cagctgagaa cacttgtcag agaatgtctc tggatgggaa 540 tagatgtggt accagctagc c 561 <210> 474 <211> 353 <212> DNA <213> HUMAN <400> 474 tctctgacca ccggtgcatg cagcccctgt cacataccgc ctgcttgctc aaatcaatca 60 tgaccctttc atgtgaaatc tttagtattg tgagccctta aaagggacgg aaattgtgca 120 tacgtggagc tcggatttta aggcagtagc tgcgtgatgc tcccagctga ataaagccct 180 tccttctaca atttggtgtc tgaggggttt tgtctgcggc tcgtcctgct acatttcttg 240 gttcctgacc aggaaacgag gtaactgatg gacagccgag gcagcccctt aggcggctta 300 ggctcccctg tggagcgtca ctcgggctgg cggagtccgc tcagggatgg tcg 353 <210> 475 <211> 448 <212> DNA <213> HUMAN <400> 475 ttaatgtcca tttagtgaat ttatttcatt aggaagacag caccatattg tactttcttc 60 ttcagctccg cttgttttct tcattaattt atcctttgaa ttccacagct ttgaaaccag 120 ccatggtacc caggaccaca gctatcacca gtattaccaa gcataggatt cccaaaatta 180 cagcaatgag gcgccaagga ggagatgcag cacacgatcc tttctctgaa acaacagcta 240 tcctggtatt gctttgagag tcgaagtgta attgagtata tccatcttca tccaaatttt 300 ctaaatcagg atgatattcc attgttcttg agagcccctg aatagatata gcatttggga 360 gctcttttct ttctgctcct gagatgactg tctgtggaca aaagagaatc tctgagtcaa 420 atcatgtggg ctaggtactt accggagt 448 <210> 476 <211> 598 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(598) <223> N=any base <400> 476 aggggtcatt ttctantgct tcaggtttgt ttgaaatcca tggagcaaca gtggttccca 60 ttgtgagtgt gctagccccg gagaagctgt cagccagcac taggaggcgc tatgaaactc 120 aggtacaaac tcgacttcag acctcccttg ccaacttaca tcagaaaagc agtgaaattg 180 aaattctggc tgtggatcta cccaaagaaa caatattaca gtttttatca ttagagtggg 240 atgctgatga acaggcattt aacacaactg tgaagcagct gctgtcacgc ctgccaaagc 300 aaagatacct caaattagtc tgtgatgaaa tttataacat caaagtagaa aaaaaggtgt 360 ctgtgctatt tctgtacagc tatagagatg actactacag aatcttattt taaccctaaa 420 gaactgtcgt taacctcatt caaacagaca gaggcttata ctggaataat ggaatgttgt 480 acattcacca taatttaaaa ttaaatntaa gaagaggctg ggtgcagtgg ctcacacctt 540 taatccagca ctttgggaan cnaggcagga agactgttga accaggagtt gagncagc 598 <210> 477 <211> 450 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(450) <223> N=any base <400> 477 ctccttcttt ggaaactggt gttcaagata aagaaatgct gaaaaaatat ggaaaatcat 60 ttagaaaaat gatttcattg tgccttcaaa aagatccaga aaaaagacca acagcagcag 120 aactattaag gcacaaattt ttccagaaag caaagaataa agaatttctt caagaaaaaa 180 cattgcagag agcaccaacc atttctgaaa gagcaanaaa ggttcggaga gtaccaggtt 240 ccagtgggcg tcttcataag acagaggatg gaggctggga gtggagtgat gatgaatttg 300 attgaagana gtgaggaagg gaaagcagca atttcacaac tcaggtctcc ccngagtgng 360 agantcaata tcaaattctg agctctttcc aacaactgat cctgtgggta ctttgctcca 420 agttccagaa cagatctctg ctcatctacc 450 <210> 478 <211> 479 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(479) <223> N=any base <400> 478 agcccgtgtc acaggtatca cccccttctt gccctcagcc cagctgctgt gcccctgcca 60 cccgcgcccc ctcagcccct tgcgcgtcgc atccaaggtc acttgtgctc gcagctccac 120 ctggagccgt tgccactgct gctgctgcgc ttccagtcag ggtgggccgc tggctcccac 180 tgggcgtcag tttggctccc aggccctggg cagtgcagcc tctgggcccg tctgctgcgc 240 tgcgttgcnt ggctgtgtgc tgggctgtct ttgctgtggg gctgcagtgg gggggggcgg 300 ggtgtctggg gacgcaggtg agtaggggag aaactggcag ggtggtaagc ttctgagcct 360 ccaggtaagt gcgtgcctgg gagatgcacc tgggagggac ctcgctgccc tcctgccgcc 420 tgcctcatcc cttctctttc cccttccaga tccagaagat gaaagaagga agtgagcat 479 <210> 479 <211> 445 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(445) <223> N=any base <400> 479 agattccaag ttcaggagaa ctcgaccgtt ggaatgccaa gatgccttgg aaacagcagc 60 ccgagccgag gnctctctct tgatgcctcc atgcattctc agctcagaat cctggatgag 120 gagcatccca agggaaagta ccatcatggc ttgagtgctc tgaagcccat ccggactact 180 tccaaacacc agcacccagt ggacaatgct gggctttttt cctgtatgac tttttcgtgg 240 ctttcttctc tggcccgtgt ggccacaaag aagggggagc tctcaatgga agacgtgtgg 300 tctctgtcca agcacgagtc ttctgacgtg aactgcagaa agacttagag aagactgtgg 360 gcaagaagag ctgaatgaag tttgggccag aacgctgcnt tccctgcgaa gggtttgtgt 420 tggaatcttc tgccgnacca ggctc 445 <210> 480 <211> 441 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(441) <223> N=any base <400> 480 tagtagagac tgggttttcg tcatgttggt caggctggtc ttgaactcct gacctcatgt 60 gatccaccca cctccgcctc ccaaagtgtt gggattacaa gcgtgaccac tgcacccagc 120 ctgtaaaata ttttaagaga tttattctga gccaaatatg agtgaccgtg gcctgtgaca 180 cagccctcag gaggtcctga gaacatgtgc ccaaggtggt cgggatacat cttggtttta 240 tgtattttag gaaggtatga gacatcaatc aaatacatat aagaaataca ttgatttggt 300 tcagaaaggc agaacaactc aaagcggggg gcttccaggc tataggtaaa tttaaacatt 360 ttctggttga caattgtttg agtttgtcta aagacctggg atccatagaa aggaatgttc 420 agtttaaaag ataaggntta t 441 <210> 481 <211> 561 <212> DNA <213> HUMAN <400> 481 atgcagtact gtaaggaaga gggacctcca gcttccacaa acaccatctt cagctgtatg 60 aaagggacgg ttgtggtgaa gtttgtcagg cacggtaagc atgctgagtg gcggggatca 120 gaactctcct atctgaacct actgaggagc aaagcagcaa ttacatggga tcctgtggct 180 ctcccgttgc agaggccaca ggaagatagg atggaacgtg actggtctcc taaccaaggt 240 gcactgagaa gcaatcaacg ggtcggtcgt ggccagtcct ggggaggtct gagtggtggt 300 ctttgggata acctttggcc ttatggattt ggactcgaaa ttagaagagc ctaccatttc 360 agatgcaatc acttttggac atgcttttgc agacagtcct taatgctgaa aacacagaga 420 atgggtaatt caagaggcct ttcttttaaa atagactttt gtgacccact aattgtaagg 480 tattgcaagg tcactttgcg tgtgtcataa agttgacttc cttattggtt gaaggtcaca 540 gaagtagtgg tttgctttga t 561 <210> 482 <211> 565 <212> DNA <213> HUMAN <400> 482 atatttcaga tataagattt cagttctcag tgagtctaag tgacagaagg aatggagacc 60 ctcttgggcc tgcttatcct ttggctgcac tgcaatgggt gagcagcaaa caggaggtga 120 cgcagattcc tgcagctctg agtgtcccag aaggagaaaa cttggttctc aactgcagtt 180 tcactgatag cgctatttac aacctccagt ggtttaggca ggaccctggg aaaggtctca 240 catctctgtt gcttattcag tcaagtcaga gagagcaaac aagtggaaga cttaatgcct 300 cgctggataa atcatcagga cgtagtactt tatacattgc agcttctcag cctggtgact 360 cagccaccta cctctgtgct gtgagggaca atgacatgcg ctttggagca gggaccagac 420 tgacagtaaa accaaatatc cagaaccctg accctgccgt gtaccagctg agagactcta 480 aatccagtga caagtctgtc tgcctattca ccgattttga ttctcaaaca aatgtgtccc 540 aagtaaggat tctgatgtgt atatc 565 <210> 483 <211> 484 <212> DNA <213> HUMAN <400> 483 ttattagttc aagaaaaggc atacacattt attcaacatg tatacctggg gagaaccagt 60 cattaccccg atgttcatta ttttgatcac cacgatagag ctgactactc tgctatgtag 120 tgcattttgg gactgcactt atgtatgttt ttgtttaacg tggacaaaga cttacagata 180 ggtgcaaaaa ataaatcctc ttttgcaacc cagaactcat tgttcagtat gagttttgat 240 acatataaga agggatatta tgatacctga gacagttgat tgatgggagt attgatagcc 300 ataaaggttg gttccaggcc aggtgcaatg ggtcaagcct gcaatcccca caccaaggtg 360 ggagtattgc ttgaaaccag gagttcaaga ccagcctagg caagaaagta agaaacacat 420 ctccacaaaa atttaaaaat tggctgggta ctggggcatg tgcttgtagt tggagttact 480 caga 484 <210> 484 <211> 573 <212> DNA <213> HUMAN <400> 484 gcattaagga cttgaatgcc accttccaga cagagaagat agggcacccc catgggctgc 60 agatcaccta caggagagat ggccacacca ggaacctgtt tgtgtatcat gaaagtggga 120 aggagatagt ggactggttc aatgccctcc gtgcagcccg tctgcagtac ctaaaaatgg 180 cctttcctga actcccagag tctgagctcg tgccattcct caccaggaac tacctcaaac 240 aaggcttcat ggaaaagact gggccaaagc agaaagaacc tttcaagaaa aggtggttcg 300 ccctggattg ccatgagcgg aggctgctct attacaagaa cccactggat gccttcgagc 360 agggccaggt ttttcttggg aacaaggagc agggatatga agcctacgaa gacctgccca 420 aggcatccga ggaaatcgct ggaaagccgg actcaccatt gtcaccccag agcggagatt 480 tgtcctcact tgccccagtg agaaggaaca gcaggaatgg ctggaaagtt tgcggggtgt 540 cctgtccagc cccttgacgc ccctcaaccg gct 573 <210> 485 <211> 566 <212> DNA <213> HUMAN <400> 485 ttctccccaa aatagccaca ttcttttatt tgatgattca atacattttt gattcaaata 60 gtcaccacat aacctaggca cgatattaag cattttacaa gcaaaatatt ttactgattt 120 tcttttaaat tgccagagta caataagtga actggttaag agacatactt ctgtacataa 180 aaatatccat gtatttatac aagtgtatgg aacagagttt aagataataa aaccacaaca 240 tcacaataaa taggatgtgt tcctactgca cagcacagca cgctttatca ggaagctgcc 300 aagtcttttt caaggtgctt tatgtttttc tgagctaggc tcagatttcc ccaaaaaagg 360 aataggttag taatggctgg atctgaatgt ctactttcat aagttgcttt ttattttcat 420 ctccaataac aggaatggaa gatatgataa tttaattatt ttcaaaaagt ctttgcaact 480 taccaattct attccaattc agttttttaa aatgcagatt aatctaactc tagcaccata 540 cgagaatgaa atacatgtat ttttgt 566 <210> 486 <211> 378 <212> DNA <213> HUMAN <400> 486 accacgaggt ggaggctgct gtgagccaag attgcaccac tgcactccag cctgggcaac 60 agggtgagac cgtgtctcta gaaaaaacaa aagccaaaag gatggcattt ggtattaaca 120 agatcttaac aagatctggg gagttgggct atgggaacac acacctgggg ggcctaagac 180 cttccagaga ccatggtgct tgagtaaagc tgaaaggagc tcgcaggccc agacaagtgg 240 tagtgtgtgt gcgcttggtt gcgagacacc atgtgcacaa acctggaggc acggtcgtct 300 tgtgagagtg tggaggtcag cttggctcat tagaaaccag ggccatggcc aggcgcggtg 360 gctcatgcct gtaatccg 378 <210> 487 <211> 452 <212> DNA <213> HUMAN <400> 487 gacagacact tcataagctt tagatttaga gaatttcaca gcataaagct catcgctgat 60 gcagtaatga aggaaatgtt ctacaagtta atagatgagt gagagaagag ggcattcata 120 ttagatttat ttacttactg aactcagagc cttgggttac tgcttgaccc ccactgttat 180 ctagtttaag ggtcctttta ttttttgttt ttttgaggtg gagtttcact cttgttcccc 240 aggctggagt gcagtggccc ggtctctgct cactgcaatc tccgcctccc agattctcct 300 gtctcagcct cccaagtagc tgggattata ggtacccacc accacgccct gctagttttt 360 gtatttttag tagagacagg gtttcaccat gttggtcagg ctggtctcga actcctgacc 420 tcaggcagtc tgcccacctc agcactttgg ga 452 <210> 488 <211> 423 <212> DNA <213> HUMAN <400> 488 ggttgctcag actgacacat gtagactaaa tagaaacccc tcagccctaa aatagaaaaa 60 agaacagttc tggactattg aacagcccat tcatttattt ctgttttgtt taccgacata 120 ttcagtatta ttcttgtttt ctgaattctg agtctcctga acaaaaggct tactatccat 180 ggtcttggaa aagattgtcc cttctcttgc tgttgtaatg catctctgct acagcagtca 240 ttgtcatcct gtgaccttat cccttttgtc tcccatcacc ttttccttct tcagcagcac 300 ctcacagtca gtcagacgct gcaggcacca ctatcaccag gagtggccaa gtaaaccgag 360 acaccagtaa cagcagggct ggagcttcct cagcgttttg ggaaggaaag agatgttccc 420 ctg 423 <210> 489 <211> 507 <212> DNA <213> HUMAN <400> 489 tttttttttg aaggttaaat tgcattattt cttttatttt tatgattttt ttaataccaa 60 aaaaaagaga caagattttg ccatgttgcc gaggctggtc tcaaactcct gacctcaact 120 gatcctcccg tctcggcctc ccaaagtgct gggatgacag gcgtgcactg ccctgccttg 180 tgcttttatt tctaaacaca ttttcctaat gtatttttct gatgactctc aaggggagga 240 tggctgtttt ggctgggtgt ggtggtgcac acctgtagtc ccagctactc aggaggctga 300 gcggggagga tcgcttgagc ccaggagttt gaggctgcag tgagctatga tggtgccact 360 gttctccagc ccaggcaaca gagcaaggcc ctgtctctaa aaaaataaat attataaaca 420 aaaaccaaaa caaaacaaaa acaaggaaga gcaactgcat agctgcctga caaaacgaga 480 gcgtggctca gccccacggc cctgcgt 507 <210> 490 <211> 657 <212> DNA <213> HUMAN <400> 490 tttttttttt agtgtcctct aattttattg atgcttcagt tttcataaag tgcaataaac 60 aacataaata gatgaaaaaa gctttgaaga tttatataca gttttgaggt taagataaat 120 tactgactat attcctttca gccttttaac tctgtgaaag ctgtaacgta cattaaaagc 180 acattgaact aggttaaata atgatctttc ccccttagat caatctagta ttaaggagta 240 tataattatg caagttcatt ctataacacg aggctagact aaaaggacaa tttttgtgct 300 acagactaaa tccagatacg gtcaggtgct gagcagtatt cctggcttca aaataggagg 360 tatctgtttc atcatctggc tgcgcgggat gaaaggcata gtctgatgct gcagattttc 420 ccagtccaca tcactgaaga gaggatgacg ttttagctct ttcattccag ctctctttgt 480 atcatcaatg gttaaaagta tttctactgc actttgaggc attatcagat aacttttctt 540 caccttctgg ccagggatat ctcttttcag aatattctgg aatacttgtt gtggtgtttc 600 atcattgaaa gggggaattc ctgttagaaa ttccaaccag caaacttcca gtggcca 657 <210> 491 <211> 510 <212> DNA <213> HUMAN <400> 491 cattgtcact gtatctgtca gaatcattac ttccattctg ccttgtattt tctgctgaag 60 aagaaattgt tggcagagga gtagaagatc ttgattctgt tccttgttcc ctcagtttca 120 aaagcttttt ctcatatagc ttcctggttg ttcccacaat aggaccagga ttcactccgt 180 atttcacaag ctgatccaaa agatcttcat tagtgagctc tgttacatct agatcatctt 240 tatcttcttg tctgggttta tcagttttat tcgtggcttt cctgccgacg gctgctcggc 300 tccggcccgc ggggcgctcc cagagccgag gaccggggtg ggctcgcgct cttcgtcact 360 ggagaagtcc gggggcccct tgctgttggt gccggcgggg agcggcggcc tggttgcgag 420 ccgtgaggtg ctgcaggtag agctggacgt acacgtcttt gcgctgctcc ccggccggca 480 gcgtcacatt gttggcgacc aactcactct 510 <210> 492 <211> 546 <212> DNA <213> HUMAN <400> 492 ggaaatacaa gggacctaga atagccaaaa caacctagaa aaaacaaact taggactctc 60 gctttcacaa tttcctacaa agcaacagaa atcaaggcaa tgtggtattg gcataagaag 120 atattataga tcattagaat acaattaaga atctataaat aaacccatac ctctatagtt 180 gatttttgac aatgggaaaa aaatcctttc cataaatggt gctctgacaa ttgaatagcc 240 acgttagaag aacgaagtca gatctctctt tcatatcata tatgaaaatt aactcaaaat 300 ggatcaaaga cctaaatgta ggagatataa ctataaaatt cttaaaactt agtcgtaaat 360 attcataacc ctggattagg cacaagcaac caaagaaaaa ataagttgga cttaaaaaca 420 gtgtttcaaa ggacattatg gagaaagtga aatgattcag agtccgtgtg attgtaatca 480 catgctgaca acactcagtc taagtcagac ttctgttgta ttctcaccac tcaatttgtg 540 cttttt 546 <210> 493 <211> 438 <212> DNA <213> HUMAN <400> 493 tttttttttt aggagagaca ggatttcacc atgttggcca ggctggtctc aaactcttga 60 cctcaagtga tctgcctgcc ttggcctccc aaagtgccag gaatacaggt atgagccact 120 gcaaccatcc acatttttta tttttgtact atatactggg gttctactac caaaaaaagg 180 aactactagc ttataaagtt tctttcacca tttaacattc tatctctcac acatcaatac 240 cactcaggaa ataggaagaa acgttgaagt gccatcaagc aagtgttacc tgtgaatctg 300 atcttgcctg cttgaccgta ctggagccag accatcaatt tcgtcaaaaa aaataattga 360 tgggcgcatc tgataggcct gatcaaacag caatcgtagc tgtctttcag attctcctac 420 ccatttactt agacaatc 438 <210> 494 <211> 483 <212> DNA <213> HUMAN <400> 494 attgccacaa agtttaactt cttcattcac aaccttgctc agcttcgttt ttctggtctt 60 ccttctaatg atgagcccat cctttcattt tcacctaaaa catactcctt tagacaagat 120 ggtcgaatca aggaagtctc tgtttttaca tatcataaga aatacaaccc agataaacat 180 tatatttatg tagtccgaat tttgagggaa ggacagattg aaccatcatt tgtcttccga 240 acatttgacg aatttcagga acttcacaat aagctcagta ttatttttcc actttggaag 300 ttaccaggct ttcctaatag gatggttcta ggaagaacac acataaaaga tgtagcagcc 360 aaaaggaaaa ttgagttaaa cagttactta cagagtttga tgaatgcttc cacggatgta 420 gcagagtgtg atcctgtttg tacctttctt caccctttac ttcgtgatga gaaagctgag 480 gga 483 <210> 495 <211> 496 <212> DNA <213> HUMAN <400> 495 ggtcgacaaa agggtagcag tttattcatc tgtgatagga aaataatact tatcttacaa 60 ggttgcaaga gctcaaggag accatgtatg taaagttcct gctgtaaata tgaactccca 120 tcctaatacc cttttacctc tctgtgggtt tgtcttgacc tggaaatttg ggctaaaact 180 tagaaaaaat tcttacatga taactcagtg atgcttactc atagtttttg gtgtttctca 240 tagataagat ataaatcagc tgggcgcggt ggctcatgcc tgtaatccca gcactttggg 300 aggccgaggc gggcagatca cctggggtcg ggaggtcgag accagcctga ccaacatgga 360 gaaacccgtc tctactaaaa tgcaaagttg gctgggcgtg gtggctcatg ctgtaatccc 420 agctacttgg gaagctgagg caggagagtt cgttgaaccc aggaagccga ggtttatgtt 480 agcgaaatcg tgcatt 496 <210> 496 <211> 466 <212> DNA <213> HUMAN <400> 496 gaccatctct actaaaaata caaaaattag ctgggtgtgg cggcacacgc tgtagtccca 60 gctacttggg aggctgaggc gggagaatca cttgaacctg ggaggcggag gttgcagtga 120 gccaagattg caccgctgca ctccagcctg gcaacagagc aagactccat ctcaaaacaa 180 acatacaaac aaaaaaaggt gcctctggtc ctgtgttttc tttttccttc tgaaagttca 240 tagaaacctg gcatatagag cttattttgc tgttttaact ggttggctcc acaaatcctg 300 ctacctgaca tcagtacagc ttgaccgcag tcaagtactt gatggcttgt tcatgtttag 360 ttcacctctt tagaaagaaa gctttgtggc caggtgcagt ggctcacgcc tgtaatccca 420 acaccttggg cagctgaggt gagcagatca cctgaggtca ggagtt 466 <210> 497 <211> 412 <212> DNA <213> HUMAN <400> 497 ccaagccctt taatattcac ttaaacagtt taggcacaag caataataaa actgcatttt 60 ttacgttaca aaaagatttt gtatgttatc tgcatgatat accaattttc tcaatctctt 120 ctgcaataac atctcattaa cactctggtc cacatgttgc actaatacat tattttccat 180 ttccaaagtt ttttagtaag tgtgcaacat tagcacatgg aaacgctcaa gctgtgtatt 240 agttcactga aatctggggt tttttcgttc tcacctgctg agcaccattt ggccagcatc 300 actacaacaa gctgattaca tcaccttgta aaacttaaga tggggatgaa tagtgtttgg 360 caattacatt tctgggagaa aaaactgctg attttttctt taactcgaca ca 412 <210> 498 <211> 502 <212> DNA <213> HUMAN <400> 498 tttttttttt tattgagaaa agcacacaca tttatttact gtaagtttta catgacagga 60 atcttcagaa atgaagacaa aaaagaaata ggaaaacttg tgtattttta tgtacagtct 120 tatgcagaag tataatcaga ggacaaaagg acataatcta atggtaataa actgtggaga 180 acttagcaag tcctatttgt ccagattctt cttggtgtct ctgtatctgt gaggataaag 240 ggtacctatg gaatgaaggt tttatgatct acttcaggga acagtcactt agggtttatg 300 gcctgcttca ggggagaagg ggtaagggga aggtatgaga aaccttgctt ctgcagtttt 360 ctcaaataac agggtgcaat attttggggt tatgtgtcct gaatcccatc aacgttaaga 420 tggagagacc agcccaaatc tttagttgga ttccagctaa gtcttataca cctaagggac 480 agaggagtag tcatatatat gc 502 <210> 499 <211> 249 <212> DNA <213> HUMAN <400> 499 gggtaacttc ctgatgttgc catgacattt gtagactgtc atggcactga tgggagtacc 60 tcttagcatg ctaatacctt ataattagca tataatgagt agtgaggacg accagaggcg 120 actttcatcg ccatcttggc tttggtgggt tttggcagcc ttctttacta atgctgtttt 180 atcaggaagg tctttgtgac cttgtatctt gtgccgacct cctatctcat cttgtgactt 240 agaatgcct 249 <210> 500 <211> 513 <212> DNA <213> HUMAN <400> 500 tttttttttt tttttttttt ttttttttta aaaagtgcat attctttaat ccaggaatta 60 ctcaagaaat ttatacattt tttaaaaaga tcaccaaatg catcccacat agttccttta 120 caataaacaa aagataaaca acctagcgtc ctgtcctata tgcgctctac cagatgactc 180 aattatattc catccatcca tggaatccta gacaatcata aaaggacatt tatgttaaca 240 tggaaagtta agatacgctt tgaagaatag gctacaagag agaatacatt acacaatcct 300 actgctgtat aaaacaaaac atctggaaga atctatgctt aaatattaat agtgtgtccc 360 gcaaagtggt aggataatag tgacttttat tctttttact tatctctatt ttctcatgtt 420 tctgtaatga acatgtttca taaaacaaaa tgggtctgtt ataaaaatct gaaaacttgt 480 ttttgaaaga gagcagtatt acaggctgta gtg 513 <210> 501 <211> 429 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(429) <223> N=any base <400> 501 catcaatgcg tacgggatta atccccgctt cagcagccat ttcatgttgg gcttcttcgc 60 tgatctcttc attgttcatc aaacgggtga gcagtaactg gaagtagtgg gccagcggtg 120 tgcgttcacc tctgcgacag gctctgcgca ttcggtcgcg tactcatcgg caatatcaaa 180 atattttagc gggatatcgt ggttcattat ttgcccctgg ggttaatgcg ctaagcataa 240 gggcggatga tagcactcgt gatccgggtc atacatcttt ttatagttaa tggcgcggcg 300 cgtntaccct caggcaggat aatgcgccgg catccgacta ttacgtttca ctcaccggcg 360 ttctgtcacc atcatacaac ggcactttgc gatagatgcg gatcagatac cataaatatg 420 cgccgccta 429 <210> 502 <211> 439 <212> DNA <213> HUMAN <400> 502 gtagcccggc tgaagaacaa caacagacaa gtgtgcattg acccgaagct aaagtggatt 60 caggagtacc tggagaaagc tttaaacaag taagcacaac agccaaaaag gactttccgc 120 tagacccact cgaggaaaac taaaaccttg tgagagatga aagggcaaag acgtggggga 180 gggggcctta accatgagga ccaggtgtgt gtgtggggtg ggcacattga tctgggatcg 240 ggcctgaggt ttgccagcat ttagaccctg catttatagc atacggtatg atattgcagc 300 ttatattcat ccatgccctg tacctgtgca cgttggaact tttattactg gggtttttct 360 aagagagaaa ttgtattatc aacagcattt tcaagcagtt agttccttca tgatcatcac 420 aatcatcatc attctcatt 439 <210> 503 <211> 558 <212> DNA <213> HUMAN <400> 503 ccctgtttgc aacaaagtat gctttaaaat gtaaactgtg gagccatttt ccttgcgttg 60 tccagaagga acttcgtcct gcgtgacgct ggattaatca tgagagagct cgtcaacatt 120 ccactggtac atattcttac tctggttgcc ttcagcggaa ctgagaaact tccaaaagct 180 cctgtcatca ccactcctct tgaaacagtg gatgccttag ttgaagaagt ggctactttc 240 atgtgtgcag tggaatccta cccccagcct gagatttcct ggactagaaa taaaattctc 300 attaaactct ttgacacccg gtacagcatc cgggagaatg ggcagctcct caccatcctg 360 agtgtggaag acagtgatga tggcatttac tgctgcacgg ccaacaatgg tgtaggagga 420 gctgtggaga gttgtggagc cctgcaagtg aagatgaaac ctaaaataac tcgtcctccc 480 ataaatgtgg aaataataga gggattaaaa gcagtcctac catgtactac aatgggtaat 540 cccaaaccat cagtgtct 558 <210> 504 <211> 481 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(481) <223> N=any base <400> 504 aattcggcag aggccccaga atgcaccttt cagggcctcc ccaggctgag caggaaacag 60 ggtcgccccc accctcaccc ccggcgatgt tgcgggcccc aaaggcaggg gcacttggct 120 gttctgaatg gcggatcgat gctgaggacc cagaactcgc tcaggatgca gccgaaagcc 180 aggtgtgtgt actgggagtc ctgcagcgac accacccacg ggaactccat gctgctgacc 240 aagccctcct tggggtcagg accgtagaaa acggaagctt tctggacgcc acaacctgcg 300 gacgtgncnn ggggcctcac tgccggggca aggagacctc aggaccctct ctcctgtggg 360 ctgtctgtct cgatcatcac taacgctatc cgcaacccct tttctttctt ttgcctagtg 420 tgtcttcttc accctaaaag atgctcagtg gcatttttga atcccaaaat tatgttagac 480 t 481 <210> 505 <211> 216 <212> DNA <213> HUMAN <400> 505 ctctctcctg ccatgtaagg tttttgctaa gaaatatgct gctagcctta ttggaactct 60 catatatgtg atttatttct attctcttgc tgcttttagg attctctctt tgtctttgat 120 ttttgatagt ttgattataa tacattttgt tatagtcttg tttggataga atctgattgg 180 agacatttgg tccttatacc ttgatattat tcccca 216 <210> 506 <211> 335 <212> DNA <213> HUMAN <400> 506 gtagagacag ggtctcttta tgttgctcag acagtgaggg ttctctgtct ttccactcac 60 ctcccccttg ttgcctcttc ctccccacgt cccaccccca tgcatcttcc cacccaggcc 120 agcagacctg tcaggatgga ctggtcaacc cgcagcgtgg tggatttgat ggcgaggatt 180 cggatgtctg cagggacttt gtcccacact gtggagagag tagggaagag ggaggtcact 240 tgggaatgga attttcttcc ttccaaagaa aaacccaatc tgtgtcttga ctcgttctcc 300 tcatccatcc ttcaggtctc agggaggctc ccagg 335 <210> 507 <211> 313 <212> DNA <213> HUMAN <400> 507 ttaataatgc tattattagg agtattatta ttcgattcat atgtttactg ttcaacaaat 60 attgaatgat aaacatatat gctgggtccg gcatggtggc ccatgcctgt aattccagca 120 ctttgggagg ccaaggcggg caggtcactt gaggtcagga gtttgagacc agcctggcca 180 acgtggtgga aactccgtct gtgctaaaaa tacaaaaatt agccgggcat ggtggtgggt 240 gcctgtaatc ccagctactc gggaggctga gacgggagaa tcacttgagc ccaggagctg 300 gagtgcagtg gtg 313 <210> 508 <211> 514 <212> DNA <213> HUMAN <400> 508 atctctgccc ttacgtcgtt ctctatcccg agaccgacta cgcgttcttc tgtgactgga 60 cctttcactg ctacgactat gagaacggag acgaggtctt gacctggacc ttcttgttct 120 gctttttgac ctagacctct gaactctata ggatttccct cgaccccttg aacgacttcg 180 acttcgtttc cttctggagc cataagaaga gctactgctt gatcgatgcc tgcgtcttct 240 atcataagaa tgtgaacgag gctgaagatc tctggaccaa gatcttgact ttgatcttga 300 tttccttcct cctttctttc ggctgtatgt tctactatct gaagaactgc tcgaggagga 360 ccgtctacgg tgtttctttt ttctcttgct tctgctttct tcttcagtat ctgatgaccg 420 acgtcccatt tctggggtca gacccttggg ctcaaacttc cgttgacgtg caaaccccga 480 gtccctgatt cgttcttaaa tcaaggggcc ccgt 514 <210> 509 <211> 406 <212> DNA <213> HUMAN <400> 509 ttagagtagt tttagcaaaa ttgaatggaa ggtacggaga ttcccatgta cccctgtctc 60 ctccatcatc aacattctgc accagagcag tgcatttatt acaactgatg aacctatttg 120 atgcatcatt gtcactcaga gtccatagtt tacagtaggg ttcactcttg gtgttgtaca 180 ttctgtggat ttggacgaat gtatagtgac gcatatccac cattattgta tcatacagaa 240 cagtttcaca gccctaaaag tggggagatt ggcctcagtt cgcctaccta agagactaaa 300 tgacttaccc atatatggtt gcctccatat gaagagcagt gagaaccgcc ggccgctggt 360 gtgtctcaaa tgcctgtgaa cagtgaaatc ctcacttgga tggtgg 406 <210> 510 <211> 594 <212> DNA <213> HUMAN <400> 510 tttttttcct aaataattca gtatttattt ccttagaaca aggacaaatt tgcataacca 60 cagtagggtt gtcaaaatca gcaaatctaa tattgataca ctatacaatc ctatgaccaa 120 tctcatctac aactttattc aaattttata gaggctggga ttacaagcat gaaccactct 180 atccagctga ttccatgttc tctaacaccc tatccacaca aatctgagat gggctcaagg 240 atgaccacag gccttggaga tctctgcagt gagcatctgt gcggctgaat ctgagtaaag 300 gattctgctt caggctgctg gccagcaagg tgtctcagga gcaggctggt gcagggcagc 360 tatggagaga cattagctct gcctgcactt acagcctgag gaccaagcag gctctggagg 420 cagagaaagg cctcagcaaa gaagggcagg tcgacctgca aggaagagtg agtggaggga 480 atggggcggg gcaccacagc ctctgctaag gtctcatggc acttagcagg gtcctcagcg 540 tctgctaaga gctcaggaaa tggtacctgc tctcattcag accgtttcca tcgt 594 <210> 511 <211> 514 <212> DNA <213> HUMAN <400> 511 tttcttggct tcacaaaacc cacaccacta cttcatggat ggtatagcca ttaaccctga 60 ggcttctgtc acacaaagca aatagccatt cttctgtgct ctcataatgt tcaaccattc 120 cttttactta gagaattcca gaaactgacc ttaggagagc taaacatcaa acaaggttgc 180 gagtgtcctt ccttgggaag aaaaactgaa aaattgatta ctgcttcgct gcccccacca 240 gaccaccagg tggttcatta ctcaagagaa ccatcacaac cagacatgct gacctgcatc 300 ccctaccctt cacatgcttt gcccagccca gcctgcatac actagtcttg aaatcaattc 360 ccatgttttg tctaattaaa aaaaaaaaaa atccctaatg gcgtttcttt gggagctagc 420 cagaggatct ttctcaccgt tgctgtctcc cttgcacttg agcataagcc ccataataaa 480 agtcttatct ggaaaatctg cttggccatg agtt 514 <210> 512 <211> 506 <212> DNA <213> HUMAN <400> 512 atctcttctt tccttctctg aatctcatgc aggatttcac gttgctcctg ctcttctttc 60 cgcttggcct ccaacagcct ctgctgctcc tcctgagccc gcctttccag catttcttca 120 tgaaaagact tgggaggggg cttgttatgc tcgctgagaa atgactgcac gtggtaagcc 180 agttcaaaga tcatcacctc cccacagtgt ttcttggcca gttcttctag gcgagatttt 240 aacaaattga cactttcatt tgatagacct ttggcatttt ttaactctat ttcaggaact 300 acatctggat aggtaggtgg gcatttaacc ctcaaatcca cttttacata tacttcttca 360 ccagttaggc cttgagggta caaaactaaa ttgatttcag ggggctcttt gacccggtcg 420 caagcgtccg gccgcagtcc ttggaagtcc gggccgtaaa agggcctcca ggcctgtaac 480 ccgtggtcct gtccgtgccg gtaacc 506 <210> 513 <211> 393 <212> DNA <213> HUMAN <400> 513 tagggacaga gtctatgttg cccagtgggg ctatccacag gtgtaatcat agctcactgc 60 agcctcgaac tcctgacctc aagtgatcct gcctcctcag cctcccgagt agctgggacc 120 acaggtgcat gccactgttc atgagtttta cagactttta cattttaact tttgactctt 180 ttgtaattaa cacaacacaa atacattgta cagctgcata aaaattattt tctttatact 240 cattctgtaa gcttttttct attaattttt cttttaaaac ttttttttcc cttaaacact 300 aagacagaaa cacacacatt agcctaggcc tactcaggat cttcaatatc actgtcttcc 360 cttctacatc ttgtcccact ggaaggcctt cag 393 <210> 514 <211> 378 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(378) <223> N=any base <400> 514 acgggttcat gatggtgaat gatatagcgg gtgacagatg gctacaaacc agtcataggc 60 catcacactc aggagcatgt ctctcttcca tgcctccaaa aatggcaaag agagacatct 120 gagtcaggca gcctgcatag gagatgactc tgctgtgaga ctggatgtcc acaatcatct 180 tggggaccgt ggtggaggtg aaaccgnatg tcaggcaagg acaggttgga gaggaagaag 240 tacatggggg tgtggaggtg ggagtcaggg ctgatggcca ggatgatgag caggttcccc 300 agcaccgtga ccaggcacat ggacaggaac agcccagcaa ggactggctg cagttctgga 360 tcccctgaga cttcaaca 378 <210> 515 <211> 2380 <212> DNA <213> HUMAN <400> 515 gccaccatgg ccccgccccc accgccactg gctgccagca ccccgctcct ccatggcgag 60 tttggctcct acccagcccg aggcccacgc tttgccctca cccttacatc gcaggccctg 120 cacatacagc ggctgcgccc caaacctgaa gccaggcccc ggggtggcct ggtcccgttg 180 gccgaggtct caggctgctg caccctgcga agccgcagcc cctcagactc agcggcctac 240 ttctgcatct acacctaccc tcggggccgg cgcggggccc ggcgcagagc cactcgcacc 300 ttccgggcag atggggccgc cacctacgaa gagaaccgtg ccgaggccca gcgctgggcc 360 actgccctca cctgtctgct ccgaggactg ccactgcccg gggatgggga gatcacccct 420 gacctgctac ctcggccgcc ccggttgctt ctattggtca atccctttgg gggtcggggc 480 ctggcctggc agtggtgtaa gaaccacgtg cttcccatga tctctgaagc tgggctgtcc 540 ttcaacctca tccagacaga acgacagaac cacgcccggg agctggtcca ggggctgagc 600 ctgagtgagt gggatggcat cgtcacggtc tcgggagacg ggctgctcca tgaggtgctg 660 aacgggctcc tagatcgccc tgactgggag gaagctgtga agatgcctgt gggcatcctc 720 ccctgcggct cgggcaacgc gctggccgga gcagtgaacc agcacggggg atttgagcca 780 gccctgggcc tcgacctgtt gctcaactgc tcactgttgc tgtgccgggg tggtggccac 840 ccactggacc tgctctccgt gacgctggcc tcgggctccc gctgtttctc cttcctgtct 900 gtggcctggg gcttcgtgtc agatgtggat atccagagcg agcgcttcag ggccttgggc 960 agtgcccgct tcacactggg cacggtgctg ggcctcgcca cactgcacac ctaccgcgga 1020 cgcctctcct acctccccgc cactgtggaa cctgcctcgc ccacccctgc ccatagcctg 1080 cctcgtgcca agtcggagct gaccctaacc ccagacccag ccccgcccat ggcccactca 1140 cccctgcatc gttctgtgtc tgacctgcct cttcccctgc cccagcctgc cctggcctct 1200 cctggctcgc cagaacccct gcccatcctg tccctcaacg gtgggggccc agagctggct 1260 ggggactggg gtggggctgg ggatgctccg ctgtccccgg acccactgct gtcttcacct 1320 cctggctctc ccaaggcagc tctacactca cccgtctccg aaggggcccc cgtaattccc 1380 ccatcctctg ggctcccact tcccacccct gatgcccggg taggggcctc cacctgcggc 1440 ccgcccgacc acctgctgcc tccgctgggc accccgctgc ccccagactg ggtgacgctg 1500 gagggggact ttgtgctcat gttggccatc tcgcccagcc acctaggcgc tgacctggtg 1560 gcagctccgc atgcgcgctt cgacgacggc ctggtgcacc tgtgctgggt gcgtagcggc 1620 atctcgcggg ctgcgctgct gcgccttttc ttggccatgg agcgtggtag ccacttcagc 1680 ctgggctgtc cgcagctggg ctacgccgcg gcccgtgcct tccgcctaga gccgctcaca 1740 ccacgcggcg tgctcacagt ggacggggag caggtggagt atgggccgct acaggcacag 1800 atgcaccctg gcatcggtac actgctcact gggcctcctg gctgcccggg gcgggagccc 1860 tgaaactaaa caagcttggt acccgccggg ggcggggcct acattccaat ggggcggagc 1920 ttgagctagg gggtgtggcc tggctgctag agttgtggtg gcaggggccc tggccccgtc 1980 tcaggattgc gctcgctttc atgggaccag acgtgatgct ggaaggtggg cgtcgtcacg 2040 gttaaagaga aatgggctcg tcccgagggt agtgcctgat caatgagggc ggggcctggc 2100 gtctgatctg gggccgccct tacggggcag ggctcagtcc tgacgcttgc cacctgctcc 2160 tacccggcca ggatggctga gggcggagtc tattttacgc gtcgcccaat gacaggacct 2220 ggaatgtact ggctggggta ggcctcagtg agtcggccgg tcagggcccg cagcctcgcc 2280 ccatccactc cggtgcctcc atttagctgg ccaatcagcc caggaggggc aggttccccg 2340 gggccggcgc taggatttgc actaatgttc ctctccccgc 2380 <210> 516 <211> 490 <212> DNA <213> HUMAN <400> 516 ttttcatcca aaataggtaa aaccttgtta gccaaagcag tagcaaacca aacctcagcc 60 actttcttga gagtggttgg ctctgaactt attcagaagt acctaggtga tgggcccaaa 120 ctcgtacggg aattgttccg agttgctgaa gaacatgcac cgtccatcgt gtttattgat 180 gaaattgacg ccattgggac aaaaaggtag actttctcat acttattttg ccttgtttag 240 tagggaacac cgcatagctc ttctcttgag aatgggcaat ctcagggggc tctccctatg 300 gccacagttc ttgctgtgcg tggccttcca tgcatgcttt aggctctgct ctcccaggag 360 ccagctaaca actgcccagt aactgtgaac gtctggagag actggtcagt tatgaataac 420 catgtcttga gcacccgccc tgatccagga ccatctggac tctagggaca cagttgtgag 480 cacaagtctc 490 <210> 517 <211> 338 <212> DNA <213> HUMAN <400> 517 gagacagttt cacttttgtt gcccaggctg gagtgcagtg gcgcggtctc agctcaccgc 60 aacaagagcg aaactccatc tcaaaaaata ataataatga ggagaaggcc ttccagttat 120 ggcagcacaa agaggcaggc aatttctttc tgtaaaaaaa aaaaaaaaag caacaaccaa 180 ccaaaaaata tataaaacta gacaaaatta tttatcaaaa ccaaccattt caggaaactg 240 gaaattgaca aaatgcaggc aaaaaattga gcagcattta ttcttgaaaa actactagat 300 ctttaggcaa gtaggagatt gtggcttttt ctgcctgt 338 <210> 518 <211> 401 <212> DNA <213> HUMAN <400> 518 gcgccccgtt tcccaggacg aagggcactc cgcaccggac cccggtcccg gcgcgcggcg 60 gggcacgcgc cctcccgcgc gcgctctctg accccgtctc tctcttcctc gacttctctc 120 tggagctctt gctacctctt tcctctttct gctggtttcc aaaatccaca gtgatttggg 180 gaagtagagc aatctcccca agccgtcggc ccgattcaag tggggaatgg caagcaaaaa 240 taaattaaaa cgagaaacaa tacagtttta aaaaaaaatg tttaagaaaa aagaagaggg 300 ataaaacccg gatcaatgaa tatcaaattc cagcaccgag cgccctggcc ggtgagtccg 360 ctgaccggtc cacctaaccg ctgcgcctcc cgacagagcg c 401 <210> 519 <211> 751 <212> DNA <213> HUMAN <400> 519 tttttctggc tacaaatttt attccgttac aaatagcacc gagcccttgg ggctgcccct 60 gtggagaggg atccccctcc tggaccccca cctcctcccc tgagctaccc atgtagtgtc 120 tgggagctgg cacacggccc agggtccctc tggaagctgg gccaggccaa ggggttaggc 180 ccaggccctt cgtggggtgg gcccagggcc agctgtggca gatgtgcagg taggtgagcg 240 gcagcctctc agatgagcac actggccacg ggcacgcggg tggagcggcc ccgctggggc 300 accacaatcc ggtcgtctgt ggaccctgct tcgtgcagca ggccctgcac gtgcagctgt 360 gcccgccggc ggtcggcctc aatgaagatg gcggtgccca ggaaggctgc gccgcccagt 420 gccccaacaa acgcgcagag catgagcgag aactgcagag cccggaactc ggacaagaag 480 gaggggggcc agttccggcg caggcggtca gagatcaagc caatgaggta ggggctccca 540 gcatcaccca gcaagtggga cagcacgatc tggaaggcct ggcggtggag cgtcgggtag 600 ggatcaccac gtacagcaga atgtctgcca cgatggcccc agtcatggac aggagggtct 660 ctccaatgaa gatgaaaata taagtggcca cgatgctacc acgggcgcat gcaagggaca 720 ggaagaggag gggtgcagag cccaggatgc c 751 <210> 520 <211> 443 <212> DNA <213> HUMAN <400> 520 gctctgcttc ccttttaaat ataagttcta ccttttgtct ttgctcccac atctgaatat 60 aagtggctag aagcagccac accacttctt gatcactttg ctgcttagac atttcttctg 120 ccagataccc taaatcatca ctctcaagtt caaacttcca cagattccta gggcatgaac 180 agaaggcagc caagctcttt gctaaggcgt taacattgtg tgacctttgc aaagtgcttg 240 ggtgcattct gttcatgtcc tagctatcag cattttggtc acaaccattt aaccagtccc 300 taagaaattc caaactttcc ctcatctttc tgtcttcttc tgagccctac aaactcttcc 360 aacttctgcc tgtcaccaag ttccaaagct gcttccacat tttcaggtat ctctacagca 420 atgactcact tctcagtacc agt 443 <210> 521 <211> 435 <212> DNA <213> HUMAN <400> 521 ttaacaagtc ttgacaaatg tatgcagtcc gataacagcg tgatcacaat gtagaacagt 60 tctcagatag gcattgttta aaagtcagga aagatgtata tcagaattag agactgagat 120 ttagctgatc ttcacatttt ctgtattgtt gaaatgctta taatgcccat tttgcatcca 180 ggattgaaga ggctggccca gccagggatg aacttcgggt cccgggtgaa gaggaggatg 240 gcaaacatgc agaaaaggat gaaaacagcc tgttcggcaa acttgatggg ccccaggttc 300 tggtattctt cccgaattac agctcgagcc ctatcttctg cattggttct tatctcagat 360 ttattcttcc tccagcccct gaagctcagt cccccgtaca ggaaggagat ccagagccag 420 cctgccaaca ggaag 435 <210> 522 <211> 414 <212> DNA <213> HUMAN <400> 522 acgtttatta atactcttct gttgcccttt ggaggtctga gggggagtcc ttgcagggcc 60 tctggtctgt ccctgttcat ggaaggcagt gctcaggagg cagcagcaaa gtgccaatga 120 agcagggcgt tagtgccgat ggagcaggga gccagtaccg gtggagctgg gcgttggtgc 180 caatggagcg aggcactggt gcgggtggag cggggcgtta gtgccgatgg aatggggcac 240 cagtgccgtt ggagctggac gtagtgatga tggagcaggg tggtagtgcc gacggagctg 300 gacatagtga tgatggagcg gggtggtagt gccgatggag ccggacgtta gtgacaatgg 360 agtgggacac cagtgccgat ggagcagggc gttagtgctg atggagtggg gcac 414 <210> 523 <211> 345 <212> DNA <213> HUMAN <400> 523 ttatgtagta attactcttt attcaaatat tataataatc ttcactctac aatcataacc 60 taggaaaaac caggccatac agaggtatga gctgaaggga catggtgaga agtgaccaga 120 agacaagtgt gtgagcctct gttatgcccg gacaggcgca ccagagggct ccttggtcta 180 gcggaacgtt agcgtctggg aagacgctgt taccaagcgg attgtggtct agcagtagca 240 tcagtgccaa ggaaaagcac ccactactta gcagaccagc aaagggagtc tccctttccc 300 cgggggagtt tagagaagac tctactccac catgtcttgt ggagg 345 <210> 524 <211> 436 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(436) <223> N=any base <400> 524 gcccctatac ccaggtcgga cgacgnattt gcacgtcagg accgctacgg acctccacca 60 gagtttcctc tggcttcgca ctgcccaggc atagttcacc ttgcccgaag acttcacacc 120 cttgaggata cagaggaaca cgatgaccca ggccagcagc aggcagaggc agaggttcca 180 gcggatctcc ccagggctgc cgatgccctg gctgccttgg atgtggagga cgtagcggct 240 ccagtactcc tcgctggggc tgacggtgca ggtgaggttg aggggcaggg ctntngaccg 300 tccttggaga ctctgtgctc caggcagagt tctgtgttcc accagttgcc acagtgctcc 360 cagggtaggt cgctggtgag ggaggcgaag aggtagaaga gcacgtaggc gatgatcatg 420 ttgtagtaga tggtca 436 <210> 525 <211> 242 <212> DNA <213> HUMAN <400> 525 ctgttaaatt cctcctagaa gcaaagcacc tgagagatga gatccaagta aataagaccc 60 aaatcccgga cacgtcacac aatactcgga gctgtaccat gacttcacca ccacgcaggt 120 gtgaatgcac gacattgtcc gcagcttccg gcagaccatg gaccaataca gcacggagcc 180 cggcagatac aggttcatgg ggactgaagc ctatgcagag agtattgaca ggaccgtgat 240 gt 242 <210> 526 <211> 407 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(407) <223> N=any base <400> 526 tttttttttc ttccaggagg caaggacctt ttcctcgttt attcttatca ggaaaacttc 60 tattcaaggt agaaggacaa taagagtgaa gccttcacag ctgacagaca ctgcttgtcc 120 attggctatg tcatcctggg caaagtcctc agcctcttgg agcctgtttc cttgcctgta 180 aaatgtggac agtaatagct accctgctgg ttggttggga ggattagacg taatctatca 240 aaagtgctgc taaaactgcc cctggaangt aatggacaat gaaaaaaatc actaaaacta 300 ttttgtgtgg gagaaaaggg tttcacccag aatttaatcc aactctacta gtttgctccc 360 aaagggttct gtcaatcaca accaacttca gagtctaaaa ctgaacc 407 <210> 527 <211> 1862 <212> DNA <213> HUMAN <400> 527 ggccgctgaa tggccgagtc gctgagccgc ggctgccgga cgggacggga ccggctaggc 60 tgggcgcgcc ccccgggccc cgccgtgggc atgggcgcac tggcccgggc gctgctgctg 120 cctctgctgg cccagtggct cctgcgcgcc gccccggagc tggcccccgc gcccttcacg 180 ctgcccctcc gggtggccgc ggccacgaac cgcgtagttg cgcccacccc gggacccggg 240 acccctgccg agcgccacgc cgacggcttg gcgctcgccc tggagcctgc cctggcgtcc 300 cccgcgggcg ccgccaactt cttggccatg gtagacaacc tgcaggggga ctctggccgc 360 ggctactacc tggagatgct gatcgggacc cccccgcaga agctacagat tctcgttgac 420 actggaagca gtaactttgc cgtggcagga accccgcact cctacataga cacgtacttt 480 gacacagaga ggtctagcac ataccgctcc aagggctttg acgtcacagt gaagtacaca 540 caaggaagct ggacgggctt cgttggggaa gacctcgtca ccatccccaa aggcttcaat 600 acttcttttc ttgtcaacat tgccactatt tttgaatcag agaatttctt tttgcctggg 660 attaaatgga atggaatact tggcctagct tatgccacac ttgccaagcc atcaagttct 720 ctggagacct tcttcgactc cctggtgaca caagcaaaca tccccaacgt tttctccatg 780 cagatgtgtg gagccggctt gcccgttgct ggatctggga ccaacggagg tagtcttgtc 840 ttgggtggaa ttgaaccaag tttgtataaa ggagacatct ggtatacccc tattaaggaa 900 gagtggtact accagataga aattctgaaa ttggaaattg gaggccaaag ccttaatctg 960 gactgcagag agtataacgc agacaaggcc atcgtggaca gtggcaccac gctgctgcgc 1020 ctgccccaga aggtgtttga tgcggtggtg gaagctgtgg cccgcgcatc tctgattcca 1080 gaattctctg atggtttctg gactgggtcc cagctggcgt gctggacgaa ttcggaaaca 1140 ccttggtctt acttccctaa aatctccatc tacctgagag acgagaactc cagcaggtca 1200 ttccgtatca caatcctgcc tcagctttac attcagccca tgatgggggc cggcctgaat 1260 tatgaatgtt accgattcgg catttcccca tccacaaatg cgctggtgat cggtgccacg 1320 gtgatggagg gcttctacgt catcttcgac agagcccaga agagggtggg cttcgcagcg 1380 agcccctgtg cagaaattgc aggtgctgca gtgtctgaaa tttccgggcc tttctcaaca 1440 gaggatgtag ccagcaactg tgtccccgct cagtctttga gcgagcccat tttgtggatt 1500 gtgtcctatg cgctcatgag cgtctgtgga gccatcctcc ttgtcttaat cgtcctgctg 1560 ctgctgccgt tccggtgtca gcgtcgcccc cgtgaccctg aggtcgtcaa tgatgagtcc 1620 tctctggtca gacatcgctg gaaatgaata gccaggcctg acctcaagca accatgaact 1680 cagctattaa gaaaatcaca tttccagggc agcagccggg atcgatggtg gcgctttctc 1740 ctgtgcccac ccgtcttcaa tctctgttct gctcccagat gccttctaga ttcactgtct 1800 tttgattctt gattttcaag ctttcaaatc ctccctactt ccaagaaaaa aaaaaaaaaa 1860 aa 1862 <210> 528 <211> 393 <212> DNA <213> HUMAN <400> 528 ttttcagatt ccacaaggat ttattggcac cggacctagc ctggtgcccg ccccttcaag 60 gaaagacact aacaaggagg agtgccggca ccgcaagagc cctcccagaa gcgcccagac 120 tgggggtcgg ggaggacgct gccattcgtg gccaggaagg gaagggagat tccggaggag 180 ggtgggcacg gcgcagggaa aggccgggtg gtgggatggg cagggaggcg gggtaccggc 240 cccgctagaa ggggaactcg cagacgtagt agagacgccg ctggcagtcg tggtcccacc 300 aggagccgtc gtcagaggcc tgcgccacgc agttctcgag cgtgccaccg ttgggctggt 360 ccgggctgag cggatgcggc gaggcgctgg gct 393 <210> 529 <211> 927 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(927) <223> N=any base <400> 529 tttaagatgg ctgtttcata aattagttcc ctattcctaa ctttggagaa cctggttttt 60 tcttaccttt caaggtccaa atataaaact ataaactttc agtgttggac attcttgctt 120 tttgaaagca aattcctcct caattcatga cctgtgggcc agctatcatg aataatacac 180 ccatagccct tgggttttat gaatgtgact tctaaatcct cctgcataat agctttaggt 240 gacttgaaga gttaaaagct gtcattgtca tcaatattta ctgtacatca aactcattta 300 aaatgctgtt agaaattgct gactggcaag actgtcactg acaaaaacac cagtttagga 360 cagattccat gggaaacaaa ctagaataac tgaaagctaa aatagagctt aatggtagag 420 aaagtctcag aaacaaggac agagatcaca gaaaagacaa ggaaggactc ctattggttt 480 ttctgatttt gaagagctct ttgtgcttac ctatttatcc taaacaaaaa ggcatgagta 540 aaaatttcca atgtattaca aagggtattc tgtctaatgt caggctggct ctcangatgt 600 tataaacctg cccaggtatt agacttctga tgagactgtg ccttaaggac aggaatggca 660 ctttctacta aaaactactg ccatctggga gcaaagactg gggatngaaa ctacaagaca 720 aacctgtcta gtatgacttg tgatccagag cctnttgact atgggactag acangtgcaa 780 cattctttcc tttttcactg acccatanag aagttacaga ctttcattgt aatccaactt 840 accggttatt cttggagatg cccagccaat ctgtgccgat attggcccag gccaatactt 900 tagggacgtt taatcgatct atatacc 927 <210> 530 <211> 529 <212> DNA <213> HUMAN <400> 530 ttttttgagg gatgcacaag tctttattcc tgctggcaga ggaggtggtc ctgtggctgg 60 cggagtgggc acctcaggct ggcagctctc acctcttgct ggccggcagc ttcagccact 120 tgggcacctt gcccaggctc ctcttcacgg gctgggccgt ccctgggatg ggctcagggg 180 ggaccagcgc cccctcctca gcagctggct cagacttagg tgcagggtca ggggctggca 240 atggggaagg ggacccggcg gccctggaca tgtacctggc caccagcacg tcggccgcag 300 atggggagat ggcatgctcc agcaggccag gctccaggta gacacctgcc ggctcctcgg 360 ctcccaagtg caccagagcg gccgggaaga ggttcgcccg gcctgtcccc acgtgcttgt 420 gcccagcctt gactcgggag ggatcgccac tgctcggacg aggggatggt ggagaggagg 480 gtcggcagac tgggtggcat ggaggctgac cagtgcttgg agaggctcg 529 <210> 531 <211> 440 <212> DNA <213> HUMAN <400> 531 tccgatgggc acagctttat tctggaacgg tgaacccagt ggggaggatc ctgcaggcgg 60 acggcagttg gggtactata gatgactaag tagggtccag tccatcgagg ttgtagagtt 120 tgaggggtca ggttcttaat aagaactgat cgtccagcta gggtgtcttc atatagttgg 180 gaatcctcta ctgtaagagt tatccaaagc tcagcatccg taatggtcca gggggcttcc 240 aaggcgatca ggcagcatca gtcttcagct gctaagctga gaagatctgg gaaggagtca 300 gtcagagagc ctttggccag agttctaggg gccctgggag tggctgccgg gttggacagt 360 ccgatttcca gtggggtccc gatttgaaat tcatgagatg ttccttgggc tggttggtct 420 gaggacccga agtcgtaggt 440 <210> 532 <211> 527 <212> DNA <213> HUMAN <400> 532 ttttagagaa acgttgtgtt taatggtaaa gcttaacaca ccccagcacc aagaatggtg 60 tggagttgca gtagcaacag gccggtgacc ccccatggag cctcacatgg cgaagaggat 120 gaggaaggcg accatcaaac agaaaagccc catggcctca gacagggcaa agccaagaat 180 ggcataggag aagagctgct gcttgagaga cgggttcctg gcatagccaa tgatcaagct 240 gccaaacacg gttccaatgc cagcccctga accagccaca ccaactgtgg ctgccccagc 300 accaataaac ttggctgctg tgtcaatgtc ccgggagaca acactggtct ggaactcccg 360 tctggccacc tggagtggga agttgctgta ggaaggctgt ttagatgaat tcactgggct 420 attcaagaag gaggcagaca caggcctgat tagacccctg gtacaacagc ggatcagagc 480 tggagaaatg aataatgcac aggcggtctg cattttttca gtctcac 527 <210> 533 <211> 794 <212> DNA <213> HUMAN <400> 533 ttttttccaa ataactggta ataattttta ttaagttttc cctaatgcat tttcaattct 60 acatttcaag agtattgaac ttttctcact tttgcactct aatcagaaaa accagaatta 120 aatttttatt ttaaaataca tttaataaaa ataacccata gttttacata ttttacatgt 180 gtagaatatt tacaaactca cttctacagc atttacttaa tgtttactat ttttccatta 240 tttgcctttt tggctatttc cctcagtagt aaaatgttgt ccagtgttct ctttaaaaaa 300 ttagtttctt gggcaatcct ccttgttcta aggcctctgt tcttttcctt tttattgcca 360 aagctggatt tgattgctcc tttaaggttt ccactggaca gtttggtctt ggcagctgac 420 atccaagtgt tggccctggc ccgatactgg aatcacttca ttttcagtgc ctgtgtggcc 480 gtaattcgag cactgaatta aataagatta agccttgtat gagatctagt aagtcgtctc 540 ctgctgcact gaagatgtga tgcaaaggta ttccagggaa actcttaaat gtcacataat 600 ctggaagact acacatgtcc ggccactgtt cctcagttgt tgtgcccaaa gtttcaaata 660 ttctggttag ctgatcaagg tctgaatctc ctggcaaaaa aagaaccctt tagagtacct 720 ctgctatata cagccaacag cccacattgt cacacctacc catacatcct agctcccaat 780 ggaactcggg ggcc 794 <210> 534 <211> 714 <212> DNA <213> HUMAN <400> 534 tttttttttt ttttttacaa ttttactttt tggcgggtat ttaaatattt tcttatctgc 60 agagctatct caggatatga aatcataaca tgctagcaac tagtaattta acattaaaac 120 acttccctaa attattccat ggaaaagtgc atttacaata taaacatgtc atatatgaag 180 ctacaaatca taatctcact ggagtggata taaaatttca aattcagtcc aaatgagtca 240 aagaaaaaag tgctaacaga gcaaatctga aacaagttca tggggattgg gtaatgagtc 300 atcgaaacga aatcttttgg aaaccatgct gctatcctct gggatattct ctttgtcttc 360 tctatcacca caggttccat tacaggagga tttagaagtc ttgtcttcag aggaccttac 420 agaatgatcc tgagtttgag aggaactgga agtttcttca gggtgaaaca agctttcaaa 480 gtcccactgc tgtagccaag aatgagaaag gcatatctct gctgttggtc ttttctctgg 540 attttttact aagaggctct gaataaagtc tgtggccagc tgtgaaactg atgaaaaagt 600 ttcttccgaa taatctacat taacttgaga gatattgagg tatgtttctt gattatcttc 660 tcccacaaat ggtgatgtgt gagttaacaa cataattgct attataccaa tatt 714 <210> 535 <211> 600 <212> DNA <213> HUMAN <400> 535 ttttgtttcc aaaacaagaa tgctgtttat ttgctgatca aaacttgtgg gaaaaattaa 60 agtaaaaaaa tattgggaga agaatggaaa gcctttggat aaatgattag ctggttaaat 120 aaatgagcct gtgttactga atgagtatgg attgcccggt tacttttttt gtttcttgac 180 actctttgct ttgggtcgtt tactttcaat gtttgcttta gattcttcct gtccagtttt 240 tgctttagat tcttcctgtc cagtttttgc ttcagattct tcctgtccag tttttgtttt 300 agattcttcc tgtacagttt ttgttttaga ttcttcctgt tcagcttttg ctttggatag 360 tggcatcctt tcctgtttgg gttttaagtg gtttcctatc acttgccgga aaaacacaaa 420 aaccactgaa aggattaata aaataaggcg aaacattatg atggacacaa cccacattgg 480 cgaagaaatc gcccctctga gcagtcctgg aggcccactg gcaatgcttc cttcataccc 540 cacttcctca cagaatggaa gtgcccaccc atacatgcag tggcagcttt ttctggtgtt 600 <210> 536 <211> 575 <212> DNA <213> HUMAN <400> 536 ttttttttta tttttaatag tgtacattta ttcaaaagta tataaaacaa cactgtaaat 60 tatataatct cacataaaaa cactagaact tgatttgaat aacaaaacaa tctactaaga 120 agtattgctc atgaagattt ttgtgcccac ctttcctaac tcagaggccc tcatttatgt 180 cgcaacagca aggtggcagg gaatcaaaac tggcacacat tctatatcct tcacagcact 240 gcagggcagg acaagactcc gtggcaatgg ttttggcctg gctgttcttg gcccaccaca 300 ccttgtctgg gttgtgattt tttacagcca cagcttcagg ttcctttgca gcttttagcg 360 cgttgtgtat tttgaagtaa agacagagca cgacaactat cagcaggagc aaggccgcca 420 ggataccacc agcgatgaca agcataatca ctgtatggag gtcaaaagac ttcgatgtac 480 ctgcataaat aatggctcct ctgctccagg aagggcaaga aacatttcaa aaagagctcc 540 aatcatgtgt cagacatccc cttgtcaggc atcct 575 <210> 537 <211> 464 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(464) <223> N=any base <400> 537 aaacccgnca ctttattgcc aatatatatt tttaactaga gatggcatct cgctccatta 60 tcaaagctgg ccctgaactc ctgggctcac ttgattctgc ctcaggcttc agagtagctg 120 ggattacagg tgtgcgccac tgtacctggc ctcaccattc agtcttgaga gggctgtcca 180 ttggttaggc ctttaagaca gagtacaggg tctcgttctg ggggctcttg aggggacggt 240 ggctgggagg tgctctgggt gaggtggagc tggagagggc aagggaagca tagacgatgc 300 cgtcatcctt gggatttagc ttgggatctg tattttgtcc ttcattcctg atattctcat 360 atggctcctc tgtgttttgg aagggttccc tggctggggt tgtggcttta gtccgctgct 420 gaccctgngt gatggagagt ttggtcccct cgatggactg ccac 464 <210> 538 <211> 485 <212> DNA <213> HUMAN <400> 538 gttttttttt tttgttttct cacttgattt cattaagctg atcttcagtc tctgatatcc 60 tttcttccgt ttgatcaatc tggctattaa tacttacgta tgtttcacga agttctcgtg 120 ctgtgttttt cagctccatc aggtcattta tgttcttctc taaaccggtt attctagtta 180 gcaattcctc taaccttttt ttaaggctct tagcttcctt gcattgggtt ggaatatgct 240 cctttagctc ggaagagttt gttattaccc accttctgaa gcctacttct gtcaattcat 300 caaactcatt ctccatccag ttttgttccc atgctggcaa ggagttgtga tcctttggag 360 gagaagaggc gttctgggtt ttggaatttt cagccttttt gcactggtct ctccatcttc 420 atggatttat ctacctttgg tctttgatgt tggtgacatt tggatgaggt ccctgagtgg 480 acatc 485 <210> 539 <211> 428 <212> DNA <213> HUMAN <400> 539 ggtagatgca tgacttgtgt gtgatgagag aatggagaca gagtccccgg ctcctctact 60 gtttaacaac atggctttct tattttgttt gaattgttaa ttcacagaat agcacaaact 120 acaattaaaa ctaagcacaa agccattcta agtcattggg gaaacggggt gaacttcagg 180 tggatgagga gacagaatag agtgatagga agcgtctggc agatactcct tttgccactg 240 ctgtgtgatt agacaggccc agtgagccgc ggggcacatg ctggccgctc ctccctcaga 300 aaaaggcagt ggcctaaatc ctttttaaat gacttggctc gatgctgtgg gggactggct 360 gggctgctgc aggccgtgtg tctgtcagcc caaccttcac atctgtcacg ttctccacac 420 gggggaga 428 <210> 540 <211> 590 <212> DNA <213> HUMAN <400> 540 ttttttgtat ttttagtaga gacggggttt ccccgtgtta aacaggatgg tctcgatctc 60 ctgacctcat gatccgcccg cctcggcgtt ggcctcccaa agtgctgaga ttacaggcat 120 gagccaccgt gcccagccaa caacccctct ccttttatgt atggaacagg gcactgggac 180 cagagaggac aaggggctag ccggggtcag ataattggga ccagaactct aacccttggc 240 catgcccatt ccaaggaggg aagccaggag atttgtgtct gcctgtccca gaggtaagag 300 gccctccagc caggccactg taaggaggct ggcccacctg gtgcatattc catggcgatc 360 ataagggctt tgtcttccag gaagttctcg tagtactcaa tgacattggg gtggttgagc 420 agcttgagga cctggcactc attctgggct gcctgccgct cttccttggt catctgttcc 480 actggaatct gcttgatgat caccagcttc tggtcagcct ttcgcaggca caggtgcaca 540 atcccgaaag cacctcttcc caccactcgg atccgctcgt acttctccat 590 <210> 541 <211> 421 <212> DNA <213> HUMAN <400> 541 ttttgcattt tcactgaagc atttattatg caaaatagga aggctttagc atgccagtat 60 aaattaaaac agtagaaaaa aagcagagca gagagcgttt tccatccatg gcctgtgccc 120 tgtaatgacg cagcagtatc ctagtacatt gacgggtttt tcctgtcctg ccactgtccg 180 ctgggcagtt ataggtccca agtgttgggt cttcctgcga ggccttcaca aagatgattt 240 tgtcattcgc tgaaagtgga agtgaatcaa cggcctcctc ttgctccgca gcactttatt 300 cacactgtgt aaccacatgt tttttatgcc actttgtgca cagctcatca aggtcagtct 360 gttcatcttc tggcccctgt agcacatggt acagttcaat ggtgcggcac agaggcctga 420 g 421 <210> 542 <211> 507 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(507) <223> N=any base <400> 542 tgttatttat ttatttattt atttatttat ttatttattt atttatagag acaagggctt 60 gccatgttac ccaggctggt cttgaactct tgagctcgag cgatccccac ctcccaaagt 120 gctgggctta caggtgtaag ccatcatgtc cagccgttca gatattctag ttgaattgga 180 gttggtgggc tagtacacct tctaaattaa atgagtaaag gatttagaat ggtgcctgac 240 acacagtagg tgctacattc atgttagcta ctattataaa cctttcctgc ctctgacttt 300 cagggtcttg cccaccacca gcgatgccca gcccttggta gagcttgaac caccttctat 360 aaacaggatg gcggtggaga gacaggccca gtccctgagc ccatgaggag tgtggcccct 420 tcaggcccaa agatggtgaa catcactgca gacaactcct cgatgagctg taccatcgac 480 cataccatnc accagacgct ggncccg 507 <210> 543 <211> 430 <212> DNA <213> HUMAN <400> 543 cctcgccgcc ttggggtctg ggcgcgcggt gccgtggggg tcagcagggc ggagcggctt 60 ttccaggaga aagggccctc acgggtgagc ggggcgactg ggctcccccg cggtgcagtt 120 gccccgcggg cgccggcccc ggctcaacgg attcttctcg ctcgctgccc ggaaagaacc 180 atttgggaga gcccatggtg actgcgtgag tggagcccag ctgtgtggat gccccagcat 240 ggatgactac atggtcctga gaatgattgg ggagggctcc ttcggcagag ctcttttggt 300 tcagcatgaa agcagtaatc agatgtttgc catgaaagaa ataaggcttc ccaagctttc 360 tctatacaca gattctagga ggaggctgtt ctttagccaa atgaacaccc tatattgtgc 420 cttcaagatc 430 <210> 544 <211> 339 <212> DNA <213> HUMAN <400> 544 ttttagtcga aatgtttgct ttaatagccc ccaaagtaca tattaagctt tcaactctcc 60 cccgcccccc tccccttttt tttgagacgg agtcaccagg ctggagtgca gtggggcgat 120 ctcggctcac tgcaacctcc gcctccagtc aaccccattt tgaaaagggt tttaagggga 180 aggagttaga aagggcccag tgaaggagga ggtggggctc tgggggtggg gggaatggcc 240 tccgagcagg gggagggaga gacagaaact tccagcattt ctaaatggcg tggggtttgc 300 cctggagccg gcggcggtgc acgagtagga agtccttta 339 <210> 545 <211> 460 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(460) <223> N=any base <400> 545 gtggcggagg ccagccccga gcttgcccag cggtgcttca ggcagggagg ggccaggccc 60 gccagccagg cgaaggcgca ggcagcgcgc gcggggcgcc gtaggcaccg ggccaggcgg 120 gcagccgccc tgggcccggg accgcgtacg aagccgcagc ggcacacgct gatgagcgcg 180 gcgaagacca ccgccgcata ggtggacacg tagtaggtgg ccccggccgc gtggcaggcg 240 gcctccgggc caggcccagg tagtaggtga gccacagctg cagcgtgagc gtgaagaact 300 catcaaccag agccaggttg aacaggtaga gaagcagggc ctggcccagg cgcccgccgc 360 tgcggatgaa cattgccagg gccgncacgt tggctggcag ccccaggccc agtgccaagg 420 cataggccgc gggcaccacg atgaagcgag cagggtcatc 460 <210> 546 <211> 450 <212> DNA <213> HUMAN <400> 546 tgagatggag tctcgctcta ctgtagccca ggatggagtg cagtagtgtg atcttggctc 60 actgcaaccc ctgcctcccg ggttcaagga attcccctgc cttagcctcc tgagtagctg 120 agattacagg cgcccaccac cacacctggc tgatttttgt ttcttagtag agacagggtt 180 tcaccatgtt ggccaggcta gtctcgaact gacctcaagt gatccatccg ccttggtctc 240 ccaaagtgtt gggattacag gtgtgagcca ctgtgcccag ccaagttata tctctaaagc 300 aatgtgcaaa aataaactga acttgggttg attaggtata ttcaacattt gtcgggagag 360 tagatgtttc attttatttc agtccctgtg taatttgtct tctctaatgt taaatactat 420 gtagaatgtg tctgtgtaat tttatagata 450 <210> 547 <211> 431 <212> DNA <213> HUMAN <400> 547 ttcactttac aaatagttta tttccacctt cacaaattca tgcgcctctg accattatgc 60 aaggcaacat gaattaaata cttatgtcag aacatatttg tcttacatta ttcaagataa 120 agtggatttt aaaagcaagt gggtaccaat gatggggaga tgaggagaat agggcaggca 180 gcaacagggc aacatgcatt tttcaagagt gtttattaaa ataggcagta atcagtacat 240 gtacatcata tgagcagttt ttcaaaatta gcacttccag gagaggggct acatctcagt 300 tttttctgtc tgtacagtaa aatgccaaaa gtacttccct aaagtacaaa ggcatttccc 360 tagtagtctt ggtaccagta acaatatgat tactaaacat ctccaatgtg gttttcatta 420 caaagaaaca t 431 <210> 548 <211> 658 <212> DNA <213> HUMAN <400> 548 tttttttttg agttggaaac aactttattg atacctgaga aaaagtgcag gaaaaatatt 60 cctcctgacc aggtggcctg tcccctgagg ccagatcatt ctctcgcctc tcccttaagc 120 cctgggtcat ttgggacctc actggccagc acccagaggc tgggtcacaa caccccctga 180 ggagaggctg tcactcaggt cagggccacc tgaggtttca ggagtactcc ccactggcca 240 gggcaaaggt gggcccatgg ggctgagccc caaggatgtg tgagtctgaa aatctgtcag 300 tgacaagacc ttgccatcga gaaggaagcc agtagcagca tccctggccc ggggtgacaa 360 gtactgggca gtggctgctc ggtgctcagg gtggaaccaa agagggttcc cctccaggta 420 gagcttgcgg agctcagcca gcagccacag tggtgacagc tcccggtgtc cttccagcag 480 gttgtatgcc aaatccaggt gccgcagatt cctcagctgc tctaggccat gcaggctccg 540 aagctcattg cctcgcagta tcaggacccc cagagcagcc cctgagggtc ccattcttgg 600 caccaaatgc aggcgattat aggagatgtc cagatggtgg agctcacaca aatccatc 658 <210> 549 <211> 556 <212> DNA <213> HUMAN <400> 549 tttttttttt tgtcttcagc agtgacttta tagaagtatc tatatatata catttagtac 60 aaccgacctt tggtttcttc tctcaatccc cttttcaaac gtatataaaa atatccaaag 120 gctcctccca gcccagtgtt tccaggcagc ctttcaaatc ccctctttgc cttagttggt 180 caaaagcctg tggatgcagc acccttccag gaagggagag gaagaaagtt agggctcctt 240 cttggcagcc ttgggaaacc atcggggtag agccccaagc ctagaggcgg gagcctgccg 300 tccttccatc ttgccacaca tgggcacata ctttcctgtt ccctcttgcc ctggaaggct 360 gagcctgcag tgagggaagt ggagtccttt tccctgcagg ggtcaagaga gaactccctt 420 cgccaggcgc ggtggctcac gcctgtaatc ccagcacttt gggaggctga ggcaggcaga 480 tcacgaggtc aggagatcga gaccattctg gctaacatgg tgaaaccgcg tatatactaa 540 aaatacaaaa taaatt 556 <210> 550 <211> 454 <212> DNA <213> HUMAN <400> 550 gattccaaga tacacatttt ttattattgt aacttctctg aaatcagata ttttgatggt 60 gtcccatagt gttttttgtt tcttactatt tcataaaata aaggtgcatc ttaagaatga 120 tggcatcata gatttgatac aaaaaagtac ttaggtgact cattgccagc tcacagacat 180 gtttgatgct cagtccagct cctggcgtgg tggcacgtgc ctgtaatccc cactcctcag 240 gaggctgagg caggaagatc acttgcgccc aggagtttga ggcttcagtg agttatgatc 300 gtgccactgc actccagcct gggtggcaga gtaagaccct gttttgcatc tctcaaggat 360 gtgccatgaa gctgtagcca ggtggaattg taccacagcc ctgacatgaa cacctgatgg 420 cagctgctgg gttggagcct tcaaggcctc actc 454 <210> 551 <211> 439 <212> DNA <213> HUMAN <400> 551 tttttttccg cataactctt ttaataaata aagcatattc atggcttaaa ttttaaatca 60 catttacaga tgagggaaaa cttctaggcc taaacaggta acagtaaagc gactactgct 120 ggaaagagtg gtgtgccaca tgcgccttaa gcctcaagag tggggactgc agggccaaac 180 accaaataca tcacctttag gccagacgga gagtggagac ccaggaagcc catgcaacca 240 ccatctcttg ctctgaggac tttgagtctc gcttgattca tcaaattgga catctgaatt 300 ttcttctgct gctcaatctg tttctctttc ttctcataat attccataat ctttagtctt 360 tgggtttgca caagccgacc tttctctatg ttgaactctt cttctgcctt tgcatctatt 420 tcttctgctt tctcattgg 439 <210> 552 <211> 663 <212> DNA <213> HUMAN <400> 552 tttttttttt ctgaggtaag actttattgt atacttgggt ggggtagccc agatggatgc 60 aaggttgcag gcatgggaag cagccctctt gggtgtcact ctgaaaatga agtagggtgg 120 tggccgcacc tcgccagtga attagtcccc taccaaggtc ttacagaccc acccttcctc 180 tcaccctcca gttcccactg tcctccaagg agaagagcct tgggtaagtg tccctccctc 240 cttcagagag tgggactgtc tgcctcttga aagcgaggat tgatggtggt cgtgatggca 300 cttttgtaga gaggattact gtcctgcttc cagttgagtt gttgctgctc cttctcaaag 360 cgactgtatt cccggcggtc atagatttcc accgagagcc ggtaagccag gaccagcccc 420 agccccactg ccacgatgcc ccctacgcag cccagcacaa tggcctgcgt gtggtctgct 480 cccttttctt gggtctcact ctgagcacga ccgtgcctct ggcgtcatcc tccaccaaga 540 agaagaacag ctggttgtcc agggtccgct cttttcacca ggcatcattc aggataaggg 600 ccaaaggcca ggtcacattg ttatggcaca agctgtactg gagttggtgg caaggggccg 660 tcc 663 <210> 553 <211> 789 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(789) <223> N=any base <400> 553 ttacattatc ctagaaaaca gaataattgg ctttatttgg tatcttcaag aagcttctcc 60 ttccgtagga gatgtaggtg ttgtgggaga aactgtaact ggttttcgtg taattctgtc 120 tagttctgca tgaacatcta agacaggctt ctggcctgac tttttggtgg atggtggtaa 180 accactgctt ccacctccag ccccacctgc agggctacca ccactcacac cagggcctcc 240 tggagagcca gtctttntac tcaacaaact gttgaagaaa tttgccagaa cgccttcact 300 tgtagctcca gctttcatgt ttggatcaat tttttttgac ccagcaggaa tgggtgacac 360 gctggcaaca ttagatgata cagatctatt tggtgttcgt ggggagcctc ctgggactct 420 tggtgaggca tccacaggcc ttccagctgc agttggtggt tgctttgcta aaagggactg 480 tagcttcata agaaacacct gatcatcttc tgccataatt tccttctcat gtacaaactt 540 tcgaacaggt ggtttagtta tgatgtcttc aaattatctt ctgcttttat gtttgaaaat 600 ttcatgtaat attcctattt tcttatcatt atcccacccc tgctggataa atactgcatn 660 cttttncnna cacacagcag ggatcttata gggaaatcca tatagnttct gaacgatgta 720 ttatatacta agnctataat tntgtngtct ttactgaagt gaaataagtg ctgcaccata 780 ctgaaaaca 789 <210> 554 <211> 452 <212> DNA <213> HUMAN <400> 554 gccgtcgtct gtctggtgaa catctttctc accgggagac tcagcagtgc ggttcctgca 60 ccgctcatgg acacaggcag caccagggcg gccggagaca ggccccccag tgcccccggc 120 cgtgcaccgg aggtgggacc ttcagggcca cccttgccct cgggcctgcg agacccagag 180 tgcaggcccg tggacaagga cagataggtc tgcagggagc cactggcaga cggcccagct 240 cctgcagatg cacctcggga gccctgctca gcccaggacc cgcaccccca ggtctccact 300 gccagcagca ccctgggccc ccactcgcca gagccactgg gggtctgcag gaaccccccg 360 cccccctgct ccccaatgct ggaggccagc gatgatgagg ccctgttggt ctgttgaccg 420 ctgggctcgc tggtgaccgc cacagccccg ct 452 <210> 555 <211> 428 <212> DNA <213> HUMAN <400> 555 tttgattgag agtgtgatca tgtttccagg tgagacccta ttgcatctgg cagcccgaat 60 tgggcaacaa ttcctgcaaa taagaagcca ctgctcttgt taggtaggtc atcgtcccat 120 aagccccact cggagcgctg tcataaaaga agtggcagat tcctgtggct tggtctttct 180 ccagggtgtc catggcacca attgacacct ggtcctgcaa gaacagctga ctggccatct 240 gcacgatctg gtccacgtgg atgatgcccc cgatgctggt catctccgtg tccgagagca 300 gcgtcagcac catgatggct tccaccagca gctgccggta ctcgggctgc ggcacgcggt 360 tcagcaccga ttcgacatgg acagcaaact tgatctcatg cggggtcatc tctcgggtcg 420 cgtaacta 428 <210> 556 <211> 505 <212> DNA <213> HUMAN <400> 556 gtgagcaata gttttttaat cacctggagt cagcaaaagg agatggggtg gggcagtttt 60 ataggatttg ggtaggtagt ggaaaaatta cagttaacgt gcgttttctc ttgtgggcag 120 gggtgggggt aacaaggtgc ttggtgagga gctcctgaga ctcattgtcc aggagaagga 180 atgtcacaag atcaattgat cagttagggt ggagcaggaa caaatcacaa tggtggaatg 240 tcatcagtta aggcaggaac tggctatttc acgtttatgg ttcttcagtt gcttcaggcc 300 atctggatgt atatgtgcag gtcacagggt tatgatggct tagcttgggc tcaggggcct 360 gacattgagg attctttttt atcttcctct gatgctcttc tataagaatg aatcggatga 420 agtgagggtc tcaccccaac gcggccttag cttcctcgga aggaccgaac accttggcgg 480 cagccgagga aaggggttcc acagt 505 <210> 557 <211> 480 <212> DNA <213> HUMAN <400> 557 tttttttttc ttctgggtat tataatcttt attacaaaac aagtatttta tgttgaggta 60 atatttcaaa tggtatttgt caaaaatcaa ttgaatctta catacagaat tttgctctgt 120 aaaggactca gagaacagtt ttcttctagc attgcacgca aactgatttt agaaaaaata 180 aagctaaaaa gtatctacgt aaagaggaat ttctttctcc cactcttcct gacccaatcc 240 ttcttatcat caccagtgat tagtaaggtg atgtttatgg gagttctaca aaaaaaaaaa 300 tgatgaattg gtaaattaat tgggagaaaa agattttctt atccaaaaca actcactgtg 360 ccataatttc aaagtgcttt tgcaaactaa gtattgaatc ctatagaatt tactattatt 420 tatcccaaga atagaattcc ccggtctcca atgaggaaac cctatgcaac cttccaactc 480 <210> 558 <211> 456 <212> DNA <213> HUMAN <400> 558 acaaaaaaaa tttacaagtg aaatgttact acaaaacttt ttataaggaa tttttgcaaa 60 acatttacat tttaccatca actatttctg ttttaaaatc attatgtaga tttaataccc 120 tatgctgcac atcaatttat gtgggatgac aacttagtga catgcataaa aaaacaccac 180 aaggcattaa aatggagact taaatacaaa tattgttgca ataaaacagt tataaaattt 240 aaaaatagga cctaaacatc atgcttatct aagtttgaca aattaacttt ttctcctaga 300 ttacacactt ttattactgc tctcatgaga gtgtgataaa tgacttaaca tcaagttcta 360 atgtaatcag caacacatac acaaacctaa ccaaagaaag tatactgtaa gaaaaaacta 420 ttctaacact ggagttttac catgataaat acatag 456 <210> 559 <211> 413 <212> DNA <213> HUMAN <400> 559 ttgtttttgt gcttcatgtt tattttagga gagtattggg gagcggtctg gtctctcagg 60 gatggcactc tgtgggtctg tatcgcggta ggagttggaa tgaggtgcag ggtgggcttc 120 aggaatggct ggatccaggt atcatgttgc tgactgtcat gattcgggct catttgtaat 180 acggcctctg tgtgttgagg tcgctgtaga catccgacct ctgaccctgg agctcctgat 240 aaggcgactc ggtctcagtg atacgctgtt tccgggtcgc tgcctccgca gcccctcgcc 300 cccgagggac cagccggccc aggaagtaca cggccagggc aatgagcact gtcagcacca 360 ggtctcccat cacgatccct gccagcacgc ccgggctcac cgtagagcaa ctg 413 <210> 560 <211> 680 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(680) <223> N=any base <400> 560 tttttcaggc ttccgggtct ttaatggggc gggggctggg ggcagttcat ccagaggtgg 60 ctccgaagct gaggtcaacc ttggcggctg gctcgcctac tccagggcct tcaccagggc 120 ctcgttggcc tcgattcgga tctggatctc tgcccgcgtg gcctcgtcag ctgtcctcac 180 cagctccgcc tgggccttct ccaagtttgc cttggctgcc cccaggtcca acatgtccag 240 cgtcacggcc tcttcggcca acaactgcac cgaagaatcg gcgttcactg cgatggaacc 300 gctgctcaca aagtatttgg aggtggtgcc gtcctctgca tgcaccacga ccagccccgg 360 ccgcaggacc tgcagcgtgg gcacgtgggc cgccaggatg ccgaaggctc cggtcagcgt 420 gggcacgtcc acctgccgga cgttggcacc gttgaagaac acctgcgtgg gagaggcgaa 480 ggtgaaggac atctggttgt ggccagaggc ggcagccggg gcggcggcgg cctcggcata 540 ggcacgggcg tggcggacga ggcggtcaag tccctggcgg cggagcagcg cggccggcag 600 catggcagcg gctgtccggc aggatgcggg tagcttgctg acagcgggac tccgcgcggc 660 gcgggcggcc tgnatggcga 680 <210> 561 <211> 466 <212> DNA <213> HUMAN <400> 561 atcttaactg caaatttatt tcattgattt taacattttt gattttaaca tataaataca 60 agaaaattaa ataaatcaga aaagaaatat tgcaaagaca agtcagcact cacagaaatg 120 tgtattatta ctatggttag tctgagatcc aacattcact tgaaatatat gcaagagaac 180 cttagtgaaa gacttaacta aaaggggttt gaaatgttcc taataaggat gtacttgagg 240 cactgctcaa gcagatgtag gtaggaagca agatagaccc tgtatataac taggagcaat 300 caaggctcga tacatgtagc aacaatagca gtgtaggaca gttccctgtt cccaatagct 360 actccccttg tcactgtgca ttcttcaaga cacatttaaa aaacaattat agctctggct 420 gggccagagt gtaccagtca taacaatcaa caatgtacca tgcagt 466 <210> 562 <211> 483 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(483) <223> N=any base <400> 562 ttttagggct gagaaaatat tcagtttatt aaatattgtg aatgggtgga atatcagata 60 catcatctca atatgtaaat atcctatccc atctcaacat caaatttaga ttacctggat 120 ttcttctttg cttttctcta tgattacaac agagatcatt atgtatttta ttagtttctt 180 cagtctttaa gatatttttt gaatgatgtt caaataaact ccaagttatc tccaactttt 240 tctgaacaaa atatttccat tcttaagata caggcttgta attcacatac ttgatgctac 300 tcaatggcgt cttatctgta ttttcttctc acatttgact ccagagtatt cagtgcggca 360 ggaacacaca ttgggaaata tgcatctgcc tccataaaga cattntgggt tgcaaattgg 420 tatttgacac cgcactcctt cccaggagga aggacaatgg catatgctgg gcgcaatgca 480 ttc 483 <210> 563 <211> 383 <212> DNA <213> HUMAN <400> 563 caggcacttt tttttataaa aacgcatagt ctcatttttc actctttaaa atcacattca 60 aaaatcggca aagaaacgcc ccggggaatg agtagacggg aggggagggt gcgccaaccc 120 agccccgggg gggagaaggc gcgacaccac acaggcagcg cgactggcac gagggggcat 180 gcggtgggcg aggcggcggc actgacagga cgtgggctgt ggggctggcc agcctccttg 240 ctgtgctgcc cgcccacctg gccggccccg tcctgggcag atggggtcgc acccagccca 300 gcatcagcga gacctcaggc caggcgaggc cagtatggcc caacctgcag gtgccttgct 360 gtggtccctg agcccgggtg ctg 383 <210> 564 <211> 611 <212> DNA <213> HUMAN <400> 564 ttttgagtca ttttcttgtt ctgtcaccaa ggctagagtg gagtggcacg atctcagctc 60 actgcaacct ctgccccctc ggttcaagca attctcctgc ctttgcctcc tgggtagctg 120 ggattacagg cgcctgccac catggctgcc taatttttgt atttttggta aagacagggt 180 ttcaccatct tggccagtct ggtcttggac tcctgacctc atgatccagc catgtggccg 240 cccaaagtgt tgggatgaga ggcgcaaacc accatgcccc gttctctccc acaatcttta 300 gagaaacatt ggcctcagac ctcatggcct ataccctgcc aagtaacaac tgtgccttgt 360 tgcagtacat agacgagctt tctttgcctg ccccaacctg agaggagtgt tatcggggaa 420 cccaggatct cctccatctc ctatagaaag caagttacaa aatatcaaaa aagaaagccc 480 aaattttcca tgaagaggtt acatatctag gtgtcatatt gagccacgag gaacactggt 540 ttggctatga gaagaagcaa gccatttgtg cacttctaac cccgactacg ccgatgacaa 600 taggaagttt t 611 <210> 565 <211> 430 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(430) <223> N=any base <400> 565 tttttttttt tgtttctcac tgcctgtata atcaggtctt tattcaaaag aagctgtcca 60 aaatgatttg acctttatgg aataatcaaa tttaagagtt tatgcagcag gctttcttct 120 cctctgtata ggtttttttt ctgcaggctt cttttcaggg gctggtttct tggtagctgc 180 tgcctttttt cccaccagag gcttcttctg cttcttaaca ccaacagcat ccttctttcc 240 tttcttacct accacaggct tcttgcctgc aaccgccgcc ttctcatctg atttggcttg 300 tagtgccgct gctgcagcag ctgccttatc cacccggagc ttgtgattcc tggcctggcg 360 aaaaaatgtg ttccggcgca tggtctttgc atatgggtta gcttcaacat gattctcaag 420 ttttcagtgg 430 <210> 566 <211> 472 <212> DNA <213> HUMAN <400> 566 gggtttggag tagtacctgc ggcgtgctcg agactccgac ttcggtcttg cggcgcgctc 60 gcgcccgcgg gccatgcccc actgactcta agtgggcact gccccggctc cgggagggcg 120 agaccgagcg ccggccatgg gaagcttcca gctggaagac tttgcggcgg gctggatcgg 180 aggtgcagcc agtgtcatcg tcggccaccc tctggacaca gtcaagactc gcctgcaggc 240 tggcgttggc tacggaaaca ccctcagctg catccgcgtg gtgtacagga gggagagtat 300 gttcggcttc ttcaagggca tgtccttccc cctcgccagc attgccgtct acaactccgt 360 ggtgtttggg gtcttcagta acacgcagcg gttcctcagc cagcaccgct gcggggagcc 420 agaggccagt cctccccgca cgctgtcaga cctgctcctg gccagcatgg tg 472 <210> 567 <211> 623 <212> DNA <213> HUMAN <400> 567 cagatagccc accaggggtg gggagggtga gcagggacag ggcgccccca ctgacttggg 60 accctcctcc tccaggccca cacctcagca cccaggacat ctgggccccc cgcccccagc 120 gctgtctagt ttggttgcct ggccgtcact cccagcctgg ttcccactcc tgtgtcttct 180 ggggatggcc ctcaaggaca gcatgttgac acatcaggcc cagctctatc actggggagg 240 gagataggct gccagggaca gaaagggctc tttgagaagg ccactctgcc tggagtgggg 300 gcgccgggca ctgtccccca aggtcgcggc agaggagata ggggtctgtc ctgcacaaac 360 accccacctt ccactcggct cacttaaggc aggcagccca gcccctggca gcacccacga 420 tgcgggacct gcctctcacc agcctggccc tagtgctgtc tgccctgggg gctctgctgg 480 agactgaggc cctcagagca gaggagccag ctgtgggcac cagtggcctc atcttccgag 540 agacttggac tggcctccag gcatcccaca agagcctctg tgcctggtgg cactggggcg 600 ggacagcaat ggcagcagct ccc 623 <210> 568 <211> 516 <212> DNA <213> HUMAN <400> 568 ctgttactca gggtaactgt ctgctctttc attgtgccca gagaccacat gttgaaaaat 60 gtccttggga gcttgaactt gtaaccacat ggcagttctt tctcttggtt tccaccatcc 120 aacagatagg aatttggggg ttcatgtcat acttatccct aaaaattatc ttgaacagtt 180 aaaagacttt gcaagctcag aattggctgc tctaaaatcc ttctgggaag aacaacggaa 240 accagccaat gctgtagctc aatagctaag gcttcaccat tttacaatgg tggcccaggg 300 ttcaatcctg gcttagggaa tgaatccttt ctggtttaaa atctgtataa cctttaccac 360 tggttaattc tcttcctctc cacaaaccat cttgaacttt cctttctctg agcaaaaaat 420 atcggctgtt tggcatggct aaagtcaggt aataagatat ttaaaaggat ttgagtgcta 480 tggttaaaag tcagtttgtt caagctctaa cagcct 516 <210> 569 <211> 743 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(743) <223> N=any base <400> 569 tttttttttt taaaggaagt caaaaacttt attcaggtga taaaattcca tgttccaaga 60 acatgctcta agcatgcaaa aagcacagga cactgctccc gggtgggggc tcaggtgggg 120 ccacctctga agctctgctg acccctgggc caaggccctg acagactagc aggcccagtg 180 gtcatgaaag cgtgacggcc accacatcac aagcgtgatg gcacctgcnt ggtgcagctg 240 cagtccctgg tgggccgggc actcactctg gcagccgccg tcccccacgc cagccatggt 300 tgtcccgcca tacgcagtag ttgagtgtgg tcgtgaaggc cagccaggcc aggtaggggt 360 agagcaggcg ggcggccagc gggctcacct ggtaccaggc cacggtagtg gctgccgccg 420 ccccactgac cagcaggaga tccaccaagg cccagcccat ttgtcgggca ccaaagaaga 480 tggggggcca tgcccagttc agggccagct gcccagtgta gaggcccagg ggaaccacag 540 ccttctctgt gaagcctccc agctctttcc agaaccagta ggagccgtac cccatggctg 600 agtaaagcgt gccccagaca gggcccagca ccagtggggg cggtgccacg agggcttctg 660 cagggccgcg tacccacgga gacccctcgc cgtgacaaag cggagcccac gaagcacccc 720 cagctgggcg gccacgtgaa gcc 743 <210> 570 <211> 446 <212> DNA <213> HUMAN <400> 570 ttcagttcaa catacattta ttaagcacag atggtatagg atactgattg cccccccagc 60 cctctgtgct ccccccacgc acacgctgtc tatgtcgatt aggctgctgt gccgtcggtt 120 cccttcttgg tctagcagag ccttcagctc cttgatctgc tcagccaact ccgggttcaa 180 gtcaaactcc gctgggaagg cggagatcca gtacctgacc aggtggcacg ttttcacctg 240 cagggaattg gagttgtcct tccgggattg ttggtagatg tggagcagct tggccgccag 300 cgaaggcttc gatgcacccg cggagcagct cctccaccgt gcagcccttg tccaggtcca 360 gggtgcctgc catggccgcc cggcgcgggt gggctgggcc caggctgcgc tccgggagcc 420 tcccaccggg ctcggaccga acccct 446 <210> 571 <211> 676 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(676) <223> N=any base <400> 571 tttttttaaa ctagatctaa gaaagaaaaa gtcaacactg atatacatgt tgcttgagcc 60 aaaagacata ggaaaaaaag acaacatata accattaaat tcctaagaaa tatgaggtaa 120 aaagatgaaa tctttagata atttctaagt ctgtacaaaa aagctagatt tgctactctc 180 caaaaagtgg aaggacctat tatataatat atggaaataa tttaatgcca tatcataaga 240 atgtaactag agctgtgcta agcttcatat tcgtgagggc atctaaaatg ccactccaca 300 gcacaggtgc ttctctcttc tatccattta tgcggtagtt ttcatggatt tctggccgaa 360 tgtcacagac aaaagccaag aggttgtcca agacttcatc cctgttctgc cggaagtatg 420 tctggaggat ggtcatcttc tcctgggtct ccttctccac ttcagtgctg caactgccac 480 gggatcccaa tgccgcagct tccttggcct tgaattcttt ctccctctgc aggcggtact 540 gttcaatttc agcctgagct tcttctttgg cctgcttcag cctccggttc tttcttttgc 600 gggcctcgga caccttctcg gctgcccgct tctcggcctg cagcagctgc tgaatccnct 660 gagactgact agccat 676 <210> 572 <211> 501 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(501) <223> N=any base <400> 572 tttggccatt cagtggccaa tctcctctcc aactgtcccc agccgaactc ttctccgtgt 60 tcacacactc ctcttctctc cgccaggcca ttctgccatt ctgctcttct gttcatctca 120 tctgcttgtg gagcctgggg tttggggttt atacgggtac aggatagggg agcatggcag 180 gtcaaaaggc aacttttggg ggcgaaaaca ggaatgcctg tcctcattta gggccgcagg 240 tttccaggct tgagggtggg cctttgccag ggaactgccc tcttctatcc agtatttccc 300 tgtctcctgt gtgtatcagt gacaccctgt ctctattaaa aatacaaaaa ttagcctggc 360 attgtggtgc atgcctgtag tcccagctac tcaggaggct gaggcaggag aatcgcttga 420 acctgngagg tagaagtttg cagtgagctg agatggtgcc actgcactcc agcctgngtg 480 acagagcana gctccatctc a 501 <210> 573 <211> 494 <212> DNA <213> HUMAN <400> 573 agtagagacg gggtttcacc gtgttagcca ggatggtctc gacctcctga gctcatgatc 60 cgcctgcctt ggccttccaa agtgctggga ttacaggtgt gagccgcttg cacctggcct 120 aacatctttc tatggaaggc tgaatgcata attacaacaa tctgatgagc caaagtgttg 180 atagcagtag agggcagaca aattcctagg cagacagggg caggtcccca atgaaacctg 240 atcttcaagc catagacagc ctgaagcctg aaaaccaggc agccagctcc aggtagagtc 300 catgacctga gtgagaactt ccttgatgct tttatagcca ggcaaatggt gctttttcca 360 ggactgctta tggaccaatc agcacacact cccccattct gagcccatga aacccctgga 420 ctcagctaca tgttgggact acccaccttc agatatgggt tacccacttc gggtcccctc 480 tcatgtcaaa aact 494 <210> 574 <211> 420 <212> DNA <213> HUMAN <400> 574 ttttgagttc ttcaaaatta tttattgatg cgtggaggga agcacaaccc agagaactgg 60 gcttggctct cagctgtgtg tgtatagcac agtctcaagg ctagctcttg acttctagga 120 aggtctttag ggtcagtagg gcagataatt acagcaaagt atcattgtat gtggatctac 180 tctccctctc caggcggaat gtttgaaccc caaccgggcc ccggcacacg aaagtcacat 240 ggctccccag ggggatcacg gtgcctggct cagccgagat ggagggtctg ggcagatctt 300 cctcctgcgt gtggatggtc tgggccaggc agagcactag gcccaggagg gcggtggggt 360 ggggagacat ggcccaggtc ccagcagtgc agcctggcct gaggcgcacc aatgcaagga 420 <210> 575 <211> 464 <212> DNA <213> HUMAN <400> 575 tttttcaggt atcaaggctg tttattgact cttcgcagcc agcggctctt cctctgcccc 60 tctgggatgc ctaatccccg tctcccccct ggagccaagt ggagtggctc tgagcttgac 120 cccaggcgcc ttcctcttgc caggcttccc tgccccgcag ccttggcctt cctggtttgc 180 cacaggggct gttactcctt tgattctaca tcctcctcga agtgtgtgag gtaggccatc 240 tgagccgaat cgcgcgagcc atagagagtg ttcatgctgt aggagctgcc atggaggcac 300 agggctttgg taacattgac tgtgttggcc gccaagatgt ccgcctgaat gctgtctatt 360 ttcatgtaca agtcctcagc gttgctctga ggacaggagc aagggggacc cggctggggt 420 gccagggcag tctggacttg gagttgggct tggcagaggg atgt 464 <210> 576 <211> 619 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(619) <223> N=any base <400> 576 ctgttgcaca ctgcaaatgg aaagttctgg attccaccta gggcaccatc gggaggccaa 60 tggggtcata tggagacaca cgcagatcct gcagcaaagc ttctaggttc ttcctcagca 120 tggcgtaggg cggcttctcc tcatacgtga gggccatcac caccttcagg tacttctgca 180 gggtctctga gggcctgatc cagtgaccgc agggtcccac gaagggcccc ggcttatcaa 240 caaacttctg tttttgcttc atgatgtcct cagtgttggg aaggcaattt gtccatggca 300 gaaacccgta gagccacttc agcatgcagt agcccaggct ctggaggtcg ctgcggcggg 360 agggcccgca tcccttgtgc aggtccatgc taatgaactc aaggtccccc tcgtgagggc 420 tcctgctgcc ttccacgtag gccacgtgtt tgccacttgg gcaatagcgg aaggcgaagc 480 catagcctgc caaagtcacc tgactctggt cctctggatc cacaaagata ttntcagctg 540 tcacatttcc atgaacatac tcattctcat ggaggaactc canggcatcc agcagcccgc 600 aggccacctg cagcacaga 619 <210> 577 <211> 514 <212> DNA <213> HUMAN <400> 577 cagcctggtg gctccacagg atctggtcca agctaccttt atggggtcac tcaaccaaaa 60 cacctctcag cctccatggg tggctctgtg gaaatcccct tctccttcta ttacccctgg 120 gagttagcca cagctcccga cgtgagaata tcctggagac ggggccactt ccacgggcag 180 tccttctaca gcacaaggcc gccttccatt cacaaggatt atgtgaaccg gctctttctg 240 aactggacag agggtcagga gagcggcttc ctcaggatct caaacctgcg gaaggaggac 300 cagtctgtgt atttctgccg agtcgagctg gacacccgga gatcagggag gcagcagttg 360 cagtccatca aggggaccaa actcaccatc acccaggctg tcacaaccac caccacctgg 420 aggcccagca gcacaaccac catagccggc ctcagggtca cagaaagcaa agggcactca 480 gaatcatggc acctaagtct ggacactgcc atca 514 <210> 578 <211> 614 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(614) <223> N=any base <400> 578 tggccctgaa cggctggggt cactgatatt tattgcatac aagacatggg ggcagggtaa 60 ggagggtgaa tcttctaagt gattgacaag gtgaagcaag tcatgtgatt acaggatagg 120 cggcccttcc cttttaggta gccgaagcag agagggaagg cagcatatgt cagcgttttc 180 ttctctgcac ttgtaagaaa gatcgaagac tttaagactt tcactatttc ttctaccgct 240 atctactgcg ctcttcaaag aggaaccagg agtacgggag gagcatgaaa gtggacaagg 300 agtgggacca ttgaagcaca gcaccacagg gaagggttta agcctccgga tgactgcgcg 360 caggcctgga taatatccag ccttccacaa gaagctggtg gagcagagtg ttccccaact 420 cttccaagga aaggagactc cctttcgcgg tctgctaatt aacgggtgca ttcccagaca 480 cttgcgttac cacttgacca aggagccctc aagcggccct tatgtgggcg tgacagaggg 540 ctcacctctt gccttccagg tcacttctca caatgtccct tcagcacctg accctatacc 600 caccggttat tnct 614 <210> 579 <211> 716 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(716) <223> N=any base <400> 579 ttgataatag ttcattttat taaataattt ataaagtcag accagtgcat tgggcttgtt 60 aggggaaacc attccttcct actgtcacat agcctggcag attatatcag gtgccaaaac 120 attccctttt attcaattta ttaatgagag tgtggaatta aagtagatcc ttgcatgtca 180 ggaaagctgc aacacatctg gtttaagtgg agcacaaagg taagttattc cacattcacc 240 aacttcccca cttgacctcc caccagttcc tgtctgcttt ttccatcaat caactctaag 300 atgccctaaa cccaaacagt tcccattcaa ctgtgcacaa aggtatagat atggaagaca 360 tctcactcca actctcacct ttggaattaa ataaacctgg aacagggaag gtgaactatg 420 gctgaaacca agtgaagatt tttaagaagc tttgacagaa acattaagaa taacacctga 480 atgcanatcc agaaaaaagc gctactgggg gaaaatagtc ttagccaatg ttctaaaaat 540 gctcataagg gagggttggg gaattaccct ttagacacaa gctctaagaa ctctggatac 600 caacggaact tggatggata cagtctgggc ctgctgggnc agatgttccg agggcggccc 660 ggcaagcagc ctgtcttgca catttgcact gactggctta tctacggcag agtcct 716 <210> 580 <211> 332 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(332) <223> N=any base <400> 580 agacagagtc tcgctctatt gcgccactgc actccaggct gggcaacaaa gcgagactcc 60 gcctcaaaaa gaaaaaaaaa agcatgggtt tgtgtaccaa acctcagtcc tccatcatcc 120 tccctgtacc tcctttttcc tttttgttga gacaaggtcc agcctgggtg acagagtgag 180 actccatctg aaaaaaaaaa aaaaaaagca tgggtttttg tgtaccaana cctcagtcct 240 ccatcatcct ccctgtacct cctttttcct tttttgttga gactccatct gaaaaaaaaa 300 aaaaaaaaac gtgggggggg ccctccaaca tc 332 <210> 581 <211> 543 <212> DNA <213> HUMAN <400> 581 gaacccggga ggcgaaggtt gcagtgagcc gagattgggc cactgcactc cagcttgggc 60 aagagcaaaa ctgtctcaaa aaaaaaaaaa aaaaaaaaaa aaaaagctac aatactcccc 120 tcacaaactg gaagcctcaa gctcttcacc ctaaaatagt tctgttgaat tttaccctgg 180 caatgtaaac tgatagctta tctgcacagg tgtgggacag aacccgtccc tctgtacacc 240 tgagtcaaat gcctatctga ctgcttcccc tgccctattt atgtaaaaat tcagagtcaa 300 tgagccagat taaggcataa gtgactattc ctctactccc tctcatatat aaattgtgta 360 ttcagtgaaa ggctgatgag tcactcaaag aatgtgataa tttattatct acctgtgacc 420 cggaagcccc ccaattccag tttttccacc tttccagacc gaattaatgt acatcttata 480 tgtattgatt gatgtctcat gtctctgtaa aatatgtaaa accaaactgc agcctgaaaa 540 cct 543 <210> 582 <211> 471 <212> DNA <213> HUMAN <400> 582 cttcacagat tttcctaaag aaacttctga ctccctttcc cttacccttt cctcttctta 60 atgctctgtt acgaaagaaa aagctgatgt tgctgttgag agtctcatac caggactgga 120 gcccccagtt ccccagcgcc tcccatctca gacggaatct gtgacctcga atcgcacaga 180 ttctctcacc ggggaagatt ccctgcttga ttgctctctg ctctctaacc ctactactga 240 ccttctggaa gagtttgccc ccacagcaat ctctgctcca gtccataaag ctgcagaaga 300 tagtaatctc atctcaggtt ttgatgtccc tgagggctcg gacaaggtgg ctgaagatga 360 gtttgaccct attcctgtat tgataaccaa aaacccacaa ggtgggcact ctagaaacag 420 cagtgggagc tctgagtcca gtcttcccaa cctagccagg tctttactgc t 471 <210> 583 <211> 512 <212> DNA <213> HUMAN <400> 583 gcggccgcaa gacccgccac gacccgctgg ccaaatccaa gatcgagcga gtgaacatgc 60 cgcccgcggt ggaccctgcg gagttcttcg tgctgatgga gcgttaccag cactaccgcc 120 agaccgtgcg cgccctcagg atggagttcg tgtccgaggt gcagaggaag gtgcacgagg 180 cccgagccgg ggttctggcg gagcgcaagg ccctgaagga cgccgccgag caccgcgagc 240 tgatggcctg gaaccaggcg gagaaccggc ggctgcacga gctgcggata gcgaggctgc 300 ggcaggagga gcgggagcag gagcagcggc aggcgttgga gcaggcccgc aaggccgaag 360 aggtgcaggc ctgggcgcag cgcaaggagc gggaagtgct gcagctgcag gaagaggtga 420 aaaacttcat cacccgagag aacctggagg cacgggtgga agcagcattg gactcccgga 480 agaactacaa ctgggccatc accagagagg gg 512 <210> 584 <211> 1172 <212> DNA <213> HUMAN <400> 584 gtgctgactt gcgggaccgc ctggaggagg acccggcgta ggccagacca ggagctgacc 60 gggagctggg gccacgggcc taggagcacc ctggtcaggg ctaaggccat ggccccgccc 120 ccaccgccac tggctgccag caccccgctc ctccatggcg agtttggctc ctacccagcc 180 cgaggcccac gctttgccct cacccttaca tcgcaggccc tgcacataca gcggctgcgc 240 cccaaacctg aagccaggcc ccggggtggc ctggtcccgt tggccgaggt ctcaggctgc 300 tgcaccctgc gaagccgcag cccctcagac tcagcggcct acttctgcat ctacacctac 360 cctcggggcc ggcgcggggc ccggcgcaga gccactcgca ccttccgggc agatggggcc 420 gccacctacg aagagaaccg tgccgaggcc cagcgctggg ccactgccct cacctgtctg 480 ctccgaggac tgccactgcc cggggatggg gagatcaccc ctgacctgct acctcggccg 540 ccccggttgc ttctattggt caatcccttt gggggtcggg gcctggcctg gcagtggtgt 600 aagaaccacg tgcttcccat gatctctgaa gctgggctgt ccttcaacct catccagaca 660 gaacgacaga accacgcccg ggagctggtc caggggctga gcctgagtga gtgggatggc 720 atcgtcacgg tctcgggaga cgggctgctc catgaggtgc tgaacgggct cctagatcgc 780 cctgactggg aggaagctgt gaagatgcct gtgggcatcc tcccctgcgg ctcgggcaac 840 gcgctggccg gagcagtgaa ccagcacggg ggcccgcggg aggactcaga ctccagcact 900 tccagcagcg cctgccctct atggacgaca gcccggagct gcccacgggc tgcagccagt 960 atgccaggga gctgccctct tcttccacaa cagctggctc tggggttctc aagatttatt 1020 caggatcgtg ttaacggagg cggtgggagg atagggtccc tgacgtgccg gggacacaca 1080 cagagaaccc tccccgcccc cgcaagggag gggggaggct cgctttttct taaaaatata 1140 aatgtattta tctgcaaaaa aaaaaaaaaa aa 1172 <210> 585 <211> 648 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(648) <223> N=any base <400> 585 tgacttggcc cacagagctt tattggagag atacacacaa aggctgtcca ctcacttcca 60 taatttcttg atggacatgt ttttctcact gtccttctgc atgaccttgg ctactgccat 120 ctcaaagtcc tcctgagtga catggactcg ccgttctcgc agggcataca tgccagcttc 180 tgtgcacacg cccttcactt cagcccctga tgctcctggc atgagctcag caatttttct 240 caggttgatc ccccgggtca ggttcatctt ccgagaatga atcttcaaaa tgtccagccg 300 ggcctcctca ttggggggtg ggaattcaat ttttctgtca atgcgccctg ggcgaagcag 360 tgccgagtcc aggatatcaa tcctattagt agccatgata accttgatgt tcttggtggc 420 ctcaaagccg tcgagctggt tgagcaactc cagcatcgtg cgctgcactt cactgtcccc 480 tccagaaccc ccctccagcc gcgaggagcc gatggagtcg atttcgtcca tgaagatgat 540 agatggagca tgttcccgtg ccatgacaaa cagctccctc accattcttg ccccttcccc 600 tatgaatttc tgtaccagnt cagagccaga gacacgaaat aacgtaca 648 <210> 586 <211> 471 <212> DNA <213> HUMAN <400> 586 tagcattcca tcatgtttat tgactcctgg gggacaggtc acaaagtcag tttgtgggca 60 ggccagactg ccctagaagg aagtcagggg cctcaagggg tggcactctt ccttaactcg 120 taactcttgg aggcaagctt ggaaggtgct ttatttcccg ctatgattat accaaccctg 180 tggcctgctc caggcttcag gatctttagg gccttcttgc gaacctactg gtggggggtg 240 ctgcaagccc ctccccttgc ccgaaggtgc caagccccat gtgggcaagg cagttgtctg 300 ttgcatagtc aagtagttgt tgtctccaac ttgcacccca gagcagttgt atatgttaac 360 gagcggtcgc cctgttactg gatttggctc cggggtcctg caggaccagt tcatgccttg 420 tctctcagcc ccctgattcc ctcggggtcc aggacttggt gttccagttg a 471 <210> 587 <211> 393 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(393) <223> N=any base <400> 587 tttaaaagaa aagacacctg ggcctggggg accactacca ccaagacgcg gagaccagta 60 gtggccccaa atgccaggct gcactgatat ttattggata taagacaaag gggcagggta 120 aggaatgtga accatctcca ataataggta aggtcacatg ggtcatgtgt ccactggaca 180 gggggccctt ccctgcctgg cagcagaggc agagagagag agaagagaga gagacagctt 240 atgccattat ttctgcatat cagacattta gtactttcac taatttgctc ctgctatcta 300 aaaggcagag ccaggtatac aggatggaac atgaaagcgg actangagcg tgaccactga 360 agcacagcat cacagggaga caggcctctg ata 393 <210> 588 <211> 515 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(515) <223> N=any base <400> 588 ttttttttac ttaaaagata aaacaacttt attatgacat caccattata tacagctgtg 60 cttttcacat caagttggct tagttcttgg aggaaagtct tagtgactaa aattgtacac 120 agatcacaag acaagagaac tagtctaaca aattcaataa gaaatcagga caactgtaga 180 ctatataaaa actgtcttag aaaattattt acaactttat catagtgtaa atactctaaa 240 tgtaaaataa atctatggat tttatacaaa aatactctaa agtacaaatg taagttaaat 300 gctgaataaa acattttcac cttttccagt ggatgctatt actaagacta taatctaggt 360 gtcaaaactt aaagtgataa ccacaaagca atgttttctt aatcactcat aattttacat 420 ttgttagtag tcatcacaag gtttagagtt ccactgaaaa agtctcattt ttacaaatgc 480 aactcataca ctntccttca tggacccttt ctctg 515 <210> 589 <211> 685 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(685) <223> N=any base <400> 589 cagattcctg ggtgcaaggt ggcctcatta gtgcccggag accgccccat ctccagggag 60 cagatagaca gacaaggggg tgatcagggg cacagtgatc caaccctggc ctctgaacgc 120 cgcagcggcc attccttggg cccagcctgg agacggcccc cctgcagcag gctaatctta 180 gacttgcctt tgtctggcct gggtgtggac gcaagtgcct gtcaattccc cgccacctca 240 gagcactata aaccccagac ccctgggagt gggtcacaat tgacagcctc aaggttcctg 300 gctttttgaa ccaccacaga catctccttt cccggctacc ccaccctgag cgccagacac 360 catgaacctt ccttccacaa aggtctcctg ggccgccgtg acgctactgc tgctgctgct 420 gctgctgccg cccgcgctgt tgtcgtccgg ggcggctgca cagcccctgc ccgactgctg 480 tcgtcaaaag acttgctctt gccgcctcta cgagctgctg cacggcgcgg gcaatcacgc 540 ggccggcatc ctcacgcatg ggcaagcgag gtccnggcac cccggcctcc agggtcggct 600 gcagcgccta ctgcaggcca gcggcaacca cgccgcgggc atcctgacca tgggcggncg 660 cgcaagcgca gagcccagcg cgcgc 685 <210> 590 <211> 596 <212> DNA <213> HUMAN <400> 590 tttttttatt ggaagggggg tttaattgtt tagaatttca aaatagtatt gggatgtgaa 60 acaggatgat tatcactctg ataaaaacaa gactgaactg agtccttcac tgtatttttc 120 taaagaactc acttctagtg agtaagtgtt caataacata aagttaggaa atctttatgt 180 tattaaaatt tgaatttttc tttcactgta tcccaatatt ttaaatatgc gcttcaggac 240 atttccagtt aaaataaaag tttaaataat atcctcacta cattaaaaat aagatcttta 300 agtaaacgta tttccaaatc atattgtcat tgtgcactga agttaattct ctgaagacta 360 aattatatgc aattgaggtt ctgtttccct tctaaacgtt cctttactaa tttttccaaa 420 gcgaaaagat gctcatctgc ttcttctggc acaaggttcc taatagaatt tgcaagttca 480 aaaagatatt ctgtatttct tccacttgga ccagctgcat taaaaatttg ttcagcaatg 540 tcttccagag gtgcaggacc aaagatatca ggattatcac atgttccaat atatag 596 <210> 591 <211> 788 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(788) <223> N=any base <400> 591 ttcaataaaa agacagattt tctttacaca gatttaagcc aataattttt agcaaaatga 60 tacaaaactg tcttaaccaa gtagaagatt ggtagttaca gtggaatcgt cagggagtac 120 agggcggcca ccactggagg gagctgaggc cctggaaaag gagtctgatt ctctgcaatt 180 ctctctctgc ttttcttccc agccccgtta caaccgagtt cacgtggggg gccgcagtgc 240 agccccagcg gtggcagctc ttggagtctg tccgtttagt atgtttcccc cacgagcgtc 300 gctgggtgag tggcctggag agctcccggt gttaacattt cgatcctaga ccgggggacg 360 tgtcactagt aaagccattg gtaacagagt agatcagcca tgcattgtct gcccttcaca 420 gcaataagga gagttctcat cggtgcacga cagactgaag accactggaa gccacccgac 480 caggaatcca gtgctgcctt ccgatgggag acgagcagct acttgccgtg gtgttcgaaa 540 ggaatgctat tctgtgaggt ggacatgcga gaggtatctt gtcggcctgt gaggtcggac 600 gaggagatgt tgacgggggc nccgcggtgc agccgcatac tcactttccg ctctctctcc 660 atgccggaga cggggccggg gggggagtgt anccgtgtnt gaaaggtagg ggtanaaggg 720 ttggaatnca cttccaatac tctcctaagc gagtcggaat gtgtaggagg gaatgcgtta 780 gatacagg 788 <210> 592 <211> 494 <212> DNA <213> HUMAN <400> 592 ttctttcttt ttctttttct ttctctctct ctttatcttt gtagctatct tctttaggaa 60 taaaatgtga ggcaaattgt ctgatgcaat tcccaccttg actttttcat ttggcttagt 120 gatttggggg tcctgagatt tattttcctt tcacaccata tacagaagaa gagtaaatat 180 aaaaacactt tcttgaacag caggctagca gcagggaaca ggggcatggg tgtggaaagt 240 tttcaaaaga gtttggcgtg aaagatgcca tatatactgt tccaacactt ggaacacaat 300 aactagagac acagttgtgc atgcgtggtg caatatctgg cctgcaggta ttctcagtga 360 tgatgaagaa caaggtagtg actttgaagg attctgtatg tcaagttgaa aaaaaagtct 420 gacctcctgc catatgtgaa atatacacct tccgagtctg tcagtaggct gaaagaagag 480 gatatggaag aagt 494 <210> 593 <211> 703 <212> DNA <213> HUMAN <400> 593 tctcattatt caggcgctcc agctctgaca cgtgcacttc tttattggaa aagaataaag 60 cagtcactga tgtggcaggg gcaggacacg agcagctgcc gtcctcctcc cagcgtgcct 120 ggcatggtcg caggggagcg ggtgcctgga gtcccggtga caccacgggg cacactgagg 180 gagctgagga gccggggccg cgcagcctcc tggatgctca gcggatcgtg tacttgtccc 240 acttcttttc agggtcgtag ggttcccacc ggctggcggg aaagatgtgc ttgttcttct 300 cgtaccagct cctcagcacc accttgcctg catgggactc atccttctcc acagtggcgt 360 cactgagcaa ccgcacatcg tcatgaacat caaagttgaa gagtggtcca ctcttccccc 420 gtgccttggt gacgatgaag tcgtagaagc tgtgatgctg ggagccaatg gcaggaaagc 480 ggcgtcttga tggtccatct cggtccgtcc ccacaccccc cgactgcgca cactgtcccc 540 atcagcctga gccagagccg aatgtgctgc acccactgca gatactgggg ctgaagggac 600 tcacgtgagg gatgatcaag tcctgctaga tgtacatgag ctgactcacc cctgctgacc 660 tcaggctcac tgagtcttat ccgaagatct cgagcgcctt ctg 703 <210> 594 <211> 782 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(782) <223> N=any base <400> 594 tttacatttt agaccattta atggaggtat ttgttgcaca tgtggtttta gtgtaacgta 60 aacacaacat ctctccccag aaacacttaa cctgagttgg aaatgaaata tgaactgaag 120 agattcttaa ttcacacata cacttctcct caaaatatta gcaatgattc caactgagga 180 ttctgcttga agttcaggac tcggtcccag gacaggaatg aaggaaaact ccgtgcagtt 240 cgaacgctct gctgaagtca aaggactgca cctgcgggct cttaatcaga gctagcttcc 300 tcaaacaccc gcggaacgag gtctggctgc gcaggcattt ttgcttcaca ccagcaggat 360 agccaccaac ataaatggga ttgttggtgt ccactgaggt agactgggtg tgtggacttt 420 cagcgccaac tgcgttccca tcaacaatca gagtgatacg gtgtttgctt ttgttagctt 480 gaagagtgtg ccattntcca tcacagagca cagtggcggt tntgggctca tatgcagctg 540 ttatcctgcc agcaccattg ttgacatgga acaagacctt gccgtccaca agctctagtc 600 caatggcatg cactatggca gtgctgatcc ccaggaagac gccatttctg cgagaggttc 660 gaaacttcca gtgtgatgtc acatctgact ggactttgta gccctctttg acaagagctg 720 catatncgct cccgcaaagt atgttctttc tgggccactg cgtagcacct ggtcaccgtg 780 aa 782 <210> 595 <211> 406 <212> DNA <213> HUMAN <400> 595 gcacgaggat taatggaact acttttgttt tgctatgctt ttaaagttct aagacaaccc 60 tcttctacta ccaggttggt ctagataact gtggtatgtc ttcaagtttc tagatgttca 120 taagttcttt tattacctaa aacttttctt cttaaatttc agaacaaaac agaaaacttt 180 cacagtgcag gttgagtatg ccatatctga aatgtattgg atcagttttt tggattttgg 240 actttttcag attttggaat attcacagag tacataccag ttgagcatcc caaattcaaa 300 atctgaaatg ctccagtgag catttctttt gagcatcacg ttggcatttg aaaaagttat 360 agaccgggca tggtggctca cgcctgtact cccagcactt tgggag 406 <210> 596 <211> 486 <212> DNA <213> HUMAN <400> 596 tttgcttgag aggagtgtgt ggtcattaca cggcctcctg gcccagctgc tgtcacagcc 60 ccccagtgcg agtgcccacg gggctcgggg tgtctacacc tctagccccg ccacctccgt 120 cagcccaagg tgaaaagggc cctgctggcc ctgggcggct gcaccctagg tctccaggta 180 ctggtagagc tcctccgctg ggggcacgag gctcaggtgg accaaaagca caaccaggag 240 ggcggtcagc cgcatggcca aggtctccag cctgagcgcc acttcaaact tgagcatctc 300 ccagacgacc ttggcgtggc gcaggaggct ggtgccgtag acaccccgat acgtggcgcc 360 cgccaggcgg ctccagcccc ggacagccct tttagccata aggaagtagc ggtccacggg 420 ggcgccgagg gccacgttga tagcgcgcac ggtggtgatg ttgcgcagca ccagcagcat 480 gggccg 486 <210> 597 <211> 536 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(536) <223> N=any base <400> 597 cagagtgact caatgtcatg ttcacatgga agacaacaga caatatcgac atagtctaaa 60 acaatacttc cagggcaggt gcagctccct catgggcctg ttctaaacca gcctctagga 120 gttgatccaa acaagacgac tacagaaacc cccaacaaaa cgtgccacga ccacatagca 180 tctgaaaggc aaaacaagac gctggatgtt gactttaaca tataaaaata ctggnaccaa 240 aatgaaatac aaatatatat tagaatctgt aagtattctg tataaagaga tacttttgcg 300 gttaggctac cagcaggcaa agaggagaca aagtccagcc ttttccactt cctgacacct 360 tcaccgggag ccccggccct gttgccagtg gtgttgcaag gccacagctc cctccggacg 420 caccctgctg tatctcttca tgcctaaaat gcagagcgaa ctaggggtct tcacaaaggg 480 ggacaagatg tggagagagg acttctcaga ggggtgattn tgcagtagcc accttc 536 <210> 598 <211> 460 <212> DNA <213> HUMAN <400> 598 atctcctcgt ctgccatttg ctaagactgt gggaaaagca cagtgtttgg gcggggtgta 60 ctgattttcc atgtacagtc tgtcacagct tcccttggct aggaaaggaa aatcccccga 120 cccattgtgc ttcctgggtg aggcgacgcc ctgtcatgct tcaccttgcc ctccgtgggc 180 tgcacccact gtccaaccag tcccagtgag atgaatcagg tacctcagtt ggtgatgcag 240 aaatcacccg tcttctgcgt cgatcactct gggagctgca gaccagagct gttcctattc 300 agctatcttg gaacggaacc cagccatttc tttttaatca tcacatgtta aatttgaagg 360 aactggctta gtttttagaa gagtgatcgg tctcattaaa gtggagggaa aaataggacc 420 cttaaggaaa atcaaaagat agtgacttaa tgtagctaga 460 <210> 599 <211> 407 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(407) <223> N=any base <400> 599 gcttaactat aagaccccaa attataaagc tactgcagga aaacataggg gaaacacttc 60 agaagaatag gcaaatatat tttagataag acctcaaaga tattttcaat aagggtcaac 120 aacaaaaaaa tagacaaatt ggactatatt gaactaaaat gcttctgcac agcaaaggaa 180 acaatcaggc agagtgaaga gacctgtagg aatggggaga aaatatttgc aaactctttc 240 acctgaggaa ggggactaat tntccaggaa tttaacaagg gaaggcaaaa aaactttaat 300 aggcagtgcc cttggcgggc tccttaactg ttattcccca ggcacntggg ggagggccca 360 agttcaggga gggttccant ttgagggcca ggggggtttt ccaagac 407 <210> 600 <211> 540 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(540) <223> N=any base <400> 600 ttaatgttca ccttccatgt attaatttat gtcttngntt ataattncta tctccctaaa 60 atgtataaaa ttaaactata acttgactac ctcgggcact ttctcaggac ctcttgagac 120 tgtacctgag ccatggttat tcatattggc tcagaataaa cctctttaaa tattttacag 180 agtttggctc ctttggtcaa tagctgggtg gtagctggcc aaggtgaatc tgggctgggt 240 aatttactga tttacaggag tcctgttcga cactagattc tcatcttaac agcacagatg 300 cagtgactag ttccagatta atacttgcag ctaacttgga ggtatggctg gccgctagtg 360 cttagctgtg cccttttgca tggcgccatc caggggaagn ccaaagcccc agctcagtcc 420 ccttcctgct tccgtaccct gttgtgncct ctttgaaggg ccttttctgc catgcttcct 480 ccaaggcttc agcctctctc agcctntaaa tctcacctcc tgtnatattt cctcagaggg 540 <210> 601 <211> 411 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(411) <223> N=any base <400> 601 cagggtctct naacagggca ggtcatcata gtacggggan tggtcttnca agagccgaag 60 cattttactg tgagcctgag ggaccaggct ncccatgctc ctgtgacact cagggcctcc 120 ttcgcagaca gaactctggc ctggatctcc cgctgggggc agaagaaact gatctcagcc 180 cccttcctct tttacccnca gagattcttt gaggtgctgc tcctgttcca ggagggaggg 240 ctgaagctgg cgctcaatgg gcaggggctg ggggccacca agcaatgaac cagcaggccc 300 tggagcagct gcggngactc cggatcagtg gaagtatcca gctctactgt gtccactcct 360 naggatggtt ccagggggaa ataccgccca gaaaancaag aaaggtcagc c 411 <210> 602 <211> 352 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(352) <223> N=any base <400> 602 ggagagctgt ctattcagat cctttgccca ttttaaaata aggatgtctt tntattattg 60 aattataaga ntcctttata tagtctaaat acaagtccct tgtcagatat gattggcaaa 120 tatgtnctcc cattctgtgt gttgcctttc cactttcttg atggtgtcct ttacagtaca 180 aaagtnttaa atttncataa agnctaattt gtntttaatt ttntaacttg tgcttttggt 240 gtgataatct gaggaagatg tttttaaccc tactattgag caagaatatg ggatatcaca 300 gttaattcat agtaattggg tataggctcg tgaaatgnat tcggnccttg tc 352 <210> 603 <211> 454 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(454) <223> N=any base <400> 603 agaaacagct tgctaaagcc ctctccactt gcaagataac aaaactgact gaaattggct 60 ggaactaata tgaccaacta gagtctgtgc agactgagct tgctgacatc acagcccaaa 120 tttccacatt tcattccagc tactccagaa tttgcacatg tggcccataa agaggcatga 180 agagacaact gtgcacgtcc aaggactttt cagacttcct ctttccttcc ccagaatcta 240 ccccctaaac ctttcctaat aaacatacta ccttaaggcc aatttgcggg gagacagatt 300 tgagctggac tcctgtcttc cttgttggtt atctaagtaa agctttcctt tcttcaaaaa 360 cctgggtgcc ccctaagttt gggaggtttt gcttgagccc agggagtttt gagatttagc 420 ctgnaggcaa catgggcaaa nccccacggt gtta 454 <210> 604 <211> 432 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(432) <223> N=any base <400> 604 attgaggctt ttttgtggcc tatggtctgg tttatgttta atgtacactt gagtagaatg 60 tgtattgtgc tgttgttgag tggggtgttc tgtaaatgtc tgttaggttt ttagtgtctg 120 ctgatcaagt ttttctaact cctcgttgat cttctgcctc gctctcctgt ctgttaggaa 180 cctggccctg ccaacacctt gattctggac ttccagcctc ccaaactgag acagttaatt 240 tcagtgtgaa accaccccat ttcttctgtt acaaccaccc tgacacaggc tgattgagct 300 taacctactg tgggaaataa gtgggcaacc tcagnatagt gctttgaagg gagggcggga 360 acagattggg ccattttgtg tgagtgcatg tgtgtcgttg tgtgttgcgt gcgtgcgtgt 420 gtgtgtgtng tg 432 <210> 605 <211> 385 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(385) <223> N=any base <400> 605 gaacttccac cttctcactt aaaggaagca cttgacggct tctttttggc acatccgaat 60 tgccggcatc actactctcg ggctttgggg tcattaagaa gtaaaataag ggctccttga 120 acacaagcac tactagacta cgacaattat tgatacgcag agggctcctg agtggctaac 180 aggcagggag tgcagacagt cagcgaatgt agacagacat cgtgaatagc tggacaaagg 240 atgcttctac tctcggatgg tatgagacan caggagattt cattgctctc ctcagaaagg 300 tntgaaattt cgccgggccc agtggcttat gcctgtaatc tcagcacttt ggggagaccg 360 aggtngggca gatcacctga ggtca 385 <210> 606 <211> 405 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(405) <223> N=any base <400> 606 tctctgaaag gagaggaaat cgcctccagg aaccagttcc ttaatgacgt agataggccg 60 tctttgtgtg tgaactccta tacttttgac attactggga tgattatatt gcttgaggat 120 tttggcttct agtaaaaatt ttaatttcag ttcctgggga agacgttctt gacgtgtttt 180 aacagcaaca gcaattttat cctttaatgt gaccttaaat gtggncanca aaattccctt 240 gcctcttgta acgtggcacc tttatgattg agaacccatt tcttattctc ctaatgggcc 300 atactgtgat accatggatg gctctttaat tgggaacatt ggactttttt ttttttttgg 360 caattttaaa caattggggg taaantccat ataacatcaa nttac 405 <210> 607 <211> 349 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(349) <223> N=any base <400> 607 actcttgcaa aaaatttaga acaaacctcc aaattcattt cagaagtcca gcattaccct 60 gataccaaaa tcaggcagat actttaagaa acgaaaacta caaaccaata tccctgatga 120 atgtcgatgc aaaaatcttc agcaaaacac tagcatgctt aattcaacaa cacattaaga 180 gttacaccaa ttacttttag aatgcaagaa gatggttcaa tatatgaaaa tcaaattaag 240 acatcacatt aacaaaataa tgggacaaaa accacatagg gccagggggc agtggcttca 300 tgcctgttaa tttccagtac tttggggagc ccgtgggtgg ggcagnttc 349 <210> 608 <211> 341 <212> DNA <213> HUMAN <400> 608 tcggctcact acaacctcca cctcctgggt tcaagtgatt ctcctgcctc agcttcccga 60 gtagctggga ttacaggcgt gtgccaccac gctgcctaat tttatatttt attagagatg 120 aggtttctcc atgttggtca agctggtctc aaactcctga tctcagctga tccactctcc 180 ttggcctccc aatgtgctgg gaatacacgc gtgagcaccg tgctcagcct aaaatctttt 240 attaccagac tagccaggac agccaatatt tctgggcttt tggaattcta ccacaggtaa 300 acctcccatg tggaaattaa ttacattttt aactaagggt c 341 <210> 609 <211> 367 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(367) <223> N=any base <400> 609 gagactacat agggctcggc gtggctgaga gcagctgtgt cggcagaaag gctcgagggc 60 ttgggcatca ctggggtggc cgctggtggg gggtcaggct ccccggatgt cagcactcag 120 ccggcgncat agtccacttc gctgcgctcc cacccctcct cccggtcttc actgaagctc 180 ctttcagcga aggtaggagt gggctggacg gccagggaac tcagagctgc tgtagacctt 240 gctgaaccgg tgggagcagg aggagaactg ggggatctct gtggacgatt cttcatcatt 300 ggtctcgtcg tcctcggagc ccagatggcc ggtaacgttc cgaacgtgtt tcaaagtagc 360 tggtatc 367 <210> 610 <211> 352 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(352) <223> N=any base <400> 610 ggactttgcc tttttcttcc tataaaaggg acaacagtgc tgtccctgac tactgcaaaa 60 ccagggagac caggaggttc cttcccctgc ccgcttcctg gattcagagt taatttccct 120 gaagtctcct ggtggtagag gggaaggggc tcatttgatg tcagcaggta cgaagggaag 180 ggttggagtg ctgagaactg ccccccactt gctgttcttt ttattgcagt ggagttcaca 240 gggcccccac agaagccccc gaggctngng cgcacagtcc atccagccca cagctaacct 300 gggaccggat tgatgacctg ggtgttacct tcaatgttca tgggagctgg tt 352 <210> 611 <211> 342 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(342) <223> N=any base <400> 611 ccaaatgact taatctagtc tcaaaaaaaa aaaanaaaaa aaaaaaaaag aaatgatcat 60 tgtcagaaaa gacgcttcat taagtagtgc cagtgttttt gtttgcggtc tgcaattgtc 120 agatggtcgg tccctatntt cacagtctcg ggaggcttgg gagatatagg tcancaccct 180 ttgtgctggg ctgctctctc tgtagtcatg cttagctcag ttgttttgtg gggaagttac 240 ttaaacaggg aaattaaagt atttctgtga ctacttctgc tctnactact gcaaaacctt 300 tctcnttata gctctggggc ttatttgggc caaaattttg ac 342 <210> 612 <211> 485 <212> DNA <213> HUMAN <400> 612 tttttttttt ttgggactgt tgaccttgct gggagaaaag agacaacgac tgagcaagca 60 ctaccaccag cactgttact gggaattaga agacctgagt ttctgtccag accctcagtg 120 caaactgagg atgctccatc caaagtgaat tatgtcctgt gcctcctgat tgctgagtgt 180 tcacctggac cttctgacta ccttccctgt gctattccat cagcctacag acctggtacc 240 tggatttttg cccgagatga ttcctaccac cttactactg acgaagacac ccattccagt 300 ggaccactgt gacccaggag gcattcagcc atcatgatgt ggcctttacc tccactcctg 360 tcttgttcta cccagattca gcacagccct ttatagtgaa gtcagagtcc tcaagccaaa 420 tagctaaagc tgttttatca caacaaaggc ctagtttgtt ccatgagtgt gcatttcatt 480 tcttc 485 <210> 613 <211> 736 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(736) <223> N=any base <400> 613 tttccagagt gccttgattc aactgtttac taatcagaaa ggtcggtata gtcggtcctt 60 tttctactgc tggcaagtga tttttgtata ttttattaca aataaaacaa tattgcttga 120 cagcatcatc tgtcatctta caaatataca actacacagt cctaaagtaa tagtatgtct 180 ctagaactga gcttttctta aaaacaaaca ataactatac tattattaag tcctgcaccc 240 taaatctata cagcagcttt aatcaatgtg gaaatgaaat tatgatttat taatttacat 300 aaaattactt tatacattaa agaataattt ttcaaattgt taaaaaaaca aagtctgaag 360 ctgtcattat tgggaatcgt gggacgtggt ttgctcttct atcacctgct tcacaatttc 420 tgccagtttt agtcgatcta ctttatctgt gaatccacga ccattccagc tgaagctctg 480 cagagtatct cttaggagtt tgcattcccg gttatacttc caagcctcct gcattacttc 540 attcagtttc tcatcttcat tctctccttt accagcctgg gggagaatac actgagcaat 600 cacatctcgg agttnttcca aggcaacatt tggaatcctc ggctccattc tcatggtcgt 660 ggatatagac actgtccttt ggcttggtgc ccagtaactt ccttctccgc agaaatgggg 720 tgtcacatga tgccag 736 <210> 614 <211> 459 <212> DNA <213> HUMAN <400> 614 tataacattt taaactactt atttttattt atatcagagt aacaaatact tatgaagtcc 60 tttgaagttc agcgcacaaa tttctcgtgt ggggcggtgg gtgtggccat gttcttgctc 120 ttccttcttt acacatttga gttgtgcctt ctgttcttaa agagattttc ctttgttcaa 180 aggatttatt cctaccattt cacaaatccg aaaataattg aggaaacagg ttacatcatt 240 ccaattttgc cttgggtttg aagagtctct catggtggca cagtcctcca gggtagctat 300 gttgttgggc tcccctacat cccagaagct cagagacttt gtcaaaggtg tgccgtccac 360 ccattgccac tgaccctcga caacctggtc tgacagtcca ataaaaaact ctctcatttt 420 aggtttcttg taggaaagga attcctgctc ctcctgtga 459 <210> 615 <211> 763 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(763) <223> N=any base <400> 615 gcggccgctg ttcctgggac gtccggttga ccgctcgtct gctgcagaga ccatgtctgc 60 cgacggggca gaggctgatg gcagcaccca ggtgacagtg gaagaaccgg tacagcagcc 120 cagtgtggtg gaccgtgtgg ccagcatgcc tctgatcagc tccacctgcg acatggtgtc 180 cgcagcctat gcctccacca aggagagcta cccgcacgtc aagactgtct gcgacgcagc 240 agagaaggga gtgaggaccc tcacggcggc tgctgtcagc ggggctcagc cgatcctctc 300 caagctggag ccccagattg catcagccag cgaatacgcc cacagggggc tggacaagtt 360 ggaggagaac ctccccatcc tgcagcagcc cacggagaag gtcctggcgg acaccaagga 420 gcttgtgtcg tctaatgtgt cgggggccca agagatggtg tctagcgcca aggacacggt 480 ggccacccaa ttgtcggagg cggtggacgc gacccgcggt gctgtgcaga gcggcgtgga 540 caagacatag tccgtagtga ccggcggcgt ncaatcagtc atgggctccc gcttgggcca 600 gatggtgctg agtngggtcg acacggtgct ggggaagtct gaggagtggg cggacaacca 660 cctgcccctt acggatgccg gactggcctc gcatcgcaca tccctggatg gcctcgacct 720 cgcgtccgtg cagcagcagc agcaggaaca gagcctcatc gtn 763 <210> 616 <211> 476 <212> DNA <213> HUMAN <400> 616 gctctcaccc actttctcct gttacggcag gggaccgacc tgtttgccgt ggctgccatg 60 agtttggcca cgccctgggc ctgggccact cctcagcccc caactccatt atgaggccct 120 tctaccaggg tccggtgggc gaccctgaca agtaccgcct gtctcaggat gaccgcgatg 180 gcctgcagca actctatggt agggggagag ggacctgccg cgaaaccatc tttgccccat 240 ccagtgtcct ctgcagcagg gccaggggac gcacacctgc ctgactcttt cctcacaggg 300 aaggcgcccc aaaccccata tgacaagccc acaaggaaac ccctggctcc tccgccccag 360 cccccggcct cgcccacaca caggtgagtc ccccaccaac tcggagacct tgggtgacca 420 gctgcccagc ctcagtgtcc tctgagatgg ggatggtggg ggtccctgcc ttggag 476 <210> 617 <211> 496 <212> DNA <213> HUMAN <400> 617 ttttttgtgt taaaatattt attcttaaag ttcttaaagg tggacatgtt caaggcttaa 60 aaattaactt caaaaagtca agccaattca caaacaccta aattaggtga aggagaatct 120 ctcccaactt taaaatacac attaaatacc ttcccctcat gctgcttcat tattttttat 180 aattatctcc agttgggtgt aggctatgtc ttcttagacc gacagaaaat ttggcttttc 240 tcagaattta tgcagaatag cagaggttaa gtgttagagt ttggaagagg tcagttgttg 300 tataagcagc ttctggatca tcttccagca ctctggagag accaaaatca gaaactttgc 360 atactaagtt gctattgacc agtatattcc gagccgctag gtctcgatga acataaccca 420 tatcagaaag atacttcatg cctgatgcaa tgcctcggag cattccgacc aactggatga 480 ctgtgaagtg gccatc 496 <210> 618 <211> 574 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(574) <223> N=any base <400> 618 acatacgtac taataaacat ggaattctag ggtcttaaga gtgttcaggg gaacaggctt 60 cgctangcta agtgctcatg ggcctccttt tcacttgcgg ttctgcattt ccttttactt 120 atttttttcc caactctatc gaggtgtgat tgacaaatga aattgtaaca aaggtgtaca 180 aagtgctgaa ttgatacatg tatgtattgt gacatgatta ccacacaagt tagtgaacac 240 atctgtcacc tcaccttgtt gcttgtgtgt gtagtgagag cagttgagac ctactgttag 300 cacatttcag gtgtacagta ttgttgactc tagtcacctt gccgtccatt aggagcccca 360 gaacttacct agttcaagta gagaggttgg gctctgcctt ttaacgagtc ttaaccacta 420 ggaggggcat ttctggcatt ttcaggaaca gaattggcat attaggccga nggcttttcg 480 tgttggcatc ntgggggcag cactnctcac ccgnactcct gggaacccnc aggggccggg 540 gtttgcnttc agaggggcag gtgagaccca aaag 574 <210> 619 <211> 491 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(491) <223> N=any base <400> 619 aacagtgtgc ggtttcctca tgggcagatt tgtgtaatct caaccatagt caacaaacag 60 cccatctgca caggatcctt ccagctgctc ttccataact tcatctctcc cctcaacacc 120 tgcaaccact aagccatttt ccccctaccc gtctgtaatt ttgttatttt gagaatgcca 180 ggtaaatgga atcagagcgg ataatctttg gagcatgatt cccttgcatt cacctgtgtt 240 gtttcgtgta tccatagttt attctttttt taatctgggg ctcactggca atctccgcct 300 cctgggnttc aaggcggatt ctcctgtctc aggcctcccc agaagctggg gattacaggg 360 ggncccgnca ccatggcccg gctaaatttt ttttgtattt ttagtagagg ttgggggttt 420 caccngttgg gccagggtgg ggtcttggaa ctcttggacc tcaggtggat cccacccggg 480 tggggcttcc c 491 <210> 620 <211> 492 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(492) <223> N=any base <400> 620 gcaaatgaga cacatataga tactgagacc tgtgtgtaca gtaggaccat gcactcacac 60 ccatctggag agggagcccc cggtatacca agggagccag ttgtgttcag acacacacat 120 cacagcttga ctcactaact gaggcctttc catagctcca cagcttcccc ttctcccctg 180 tcctcaccat atgccttatc cccattctac tcccctgcta tgcaagtgcc cctgtggctt 240 gtccccaacc ccctcagcaa caaagctcag ctggggaacg agagtaattt gaagaatgct 300 tgaagtcagc gtcttccatt ccagaaagac ccccattctt cctttggggg tatgatgtgg 360 gaagctggtt tcagcccagg gacccaccac tgagggagag ggttttagga caggtggggc 420 ttatttccaa ggggnccttt ctggggcttg gagaagggct ttttacacac acacaacaca 480 tacacacaca ca 492 <210> 621 <211> 408 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(408) <223> N=any base <400> 621 ttttnaaaac ggagctcgct ctgtcaccca ggctggagtg cagtggcggg atctctagcc 60 ttcatctttc tcccatgctg gatgcttcct gccctcgaac atcaagaccc cagtgtcttt 120 gggttttgga ccgttggacc tacaccagtg atttgccagg gntcctggga ccttcgacca 180 cagactgaag gccgcactct cagcttgcct acttttgagg ttttgggcct tggactggct 240 tcctgggctc ctcagnttgc agacggccta ttgtggggan tttcaccttg tgatcgtgtg 300 agtcaattat cctagtaaac tccccttcat atacacatca gtcctattcg ttcttgtccc 360 tgtaggatca ccctgacttt gaacaggcat tgaaggaccc aacggttg 408 <210> 622 <211> 408 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(408) <223> N=any base <400> 622 tgacttgtag gctatagggg ctataatata tcaagacaat ctttatcctc atgaagctta 60 cagttaagta agagatagag attaaataat tataacaaca gagtgaagaa cagtgaagaa 120 aaagtacaga gttataatat atataatagg gccaggactg catgaggaag gtaggaaaga 180 catttcggca agaggttgtc agggaaaaga cttgcttgag aaagagccaa gttgtggggg 240 tctggctgct tagcaattga cccttaatac cttaactttt tgcttatttt ttacatggaa 300 gtaactaatt ttaaccctat tgagggaaag tactactacc cttcttaggt ttttacaggt 360 taagtaaggc cggagttacc ggngaaggtt taaaactctt tcacacgg 408 <210> 623 <211> 371 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(371) <223> N=any base <400> 623 gaataatgtc agagaaaata accagaacat tacaaataat actggaagtt gtaccagaag 60 aagataagtt atgaactaat ggncttgaga tcttggcaat ctgcccaagg ggagacacaa 120 aatagggatt ttnacttcat tttctgaaag tctagagaat tacaactttg gtgataaaca 180 aaaggagtca gttattttta ttcatatatt ttagcatatt cgaactaatt tctaagaaat 240 ttagttatan ctctatgtag ttatagaaag tgaatatgca gttattctat gagtcgcaca 300 attcttgagt ctctgatacc taccnattgg ggttaggaga aaagactaga canttactat 360 gtggtcatnt c 371 <210> 624 <211> 519 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(519) <223> N=any base <400> 624 aaaagaccaa gaaacctacc caagattctt gtgagaatac tgaagctcac caaaagaaag 60 ccagtaagaa gaaggcccct cctgtgacta aagatccctc atcattaaag gcaaccccag 120 ggattaagga ttcatcagca gcacttgcca cttctacaag tctttctgca aaaaatgtta 180 ttaaaaagaa gggagaaatt atcattttat ggacaagaaa tgatgaccgg gaaattttat 240 tggagtgtca gaaaagaggg ccatcattta aaacatttgc atatttagcc gccaagttgg 300 ataaaaatcc aaatcaggtc tcagaaagat tccagcagct aatgaagctc tttgaaaagt 360 caaaatgcag ataagttgct gaattcctgg gactcttaac tgatattgca tactacacag 420 gaagccttca aatttcctca tgtttttaaa tgagcactag aggggagggt ttatcaccct 480 ttttgggtta ccagatggat aatcccatan ttggttaat 519 <210> 625 <211> 447 <212> DNA <213> HUMAN <400> 625 aaccatggca gcatagaagt ctctgactgg accaaatgga ctggtgataa agcctaaggt 60 ccagctctgt gatcttggat aaatggttca acccctcatc acctccgtcc cttatctaaa 120 atgcaggtta gactcagtga ttggtaaagg ctctcatagt tcctttttct ctgactctgt 180 acccagactc agggagcaaa actgtcattt gccttggtag gctttttgat atctcctgaa 240 aaagcagctt cgggagggga tttagcttct gctaattctt cttcacaaag acacgtgacc 300 atttctgaat gtctggcttt aaaaagtgta acaggtggtt ggactctgca gagacctcgg 360 gttagtctgg cactgcccct taccacctat atgaccctgg gggaattatt cacctctctg 420 ctcccaagtt ttgtatatta agggtaa 447 <210> 626 <211> 450 <212> DNA <213> HUMAN <400> 626 tttttttttt tttttttttt aaatagaaaa cagctgggcc tgggggacac taccaccaaa 60 acacgaagac cggtagtggc cccgaatggc tgggcgcgct gatatttatt gtatacaaga 120 caagggggac aggcagggta aggaaggtgg gtcgtccaag tcgattgata aggtcaagca 180 agtcacgtga tcataggaca ggggtccctt tccttttagg tagctgaagc agagatggga 240 aggcaagcat acgtcagcgt tttcttctgt gcatttatca gaaattcgat caaagacttt 300 aagattttca ctatttcttc taccgctatc ttctaagaac ttcaaagagg aaccaggagt 360 acgggaagag catgaaagtg gacaaggagc gtgaccatgg aagcacagca ccacagggag 420 gggtttaggc ctccggatga ctgcgggctt 450 <210> 627 <211> 122 <212> DNA <213> HUMAN <400> 627 ggccacatgg tggtctggcc ggtggcaaca aggctataaa tcagttggtc agcattcctt 60 cctgaggtga gacactctgc aaccttggtt ccatattttg gatctcctat ggccaattcc 120 tg 122 <210> 628 <211> 221 <212> DNA <213> HUMAN <400> 628 tctcacctcg gctgccagtc cacagtgaac accaccacag acacagtgaa aggctacttc 60 ctggctggag gggacatggt gtggtggcca gtgggtgcat ccttgtttgc caccaatgtt 120 ggaagtggac atttcattgg cctggcaggg tcaggtgctg ctacgggcat ttctgcacca 180 gctcatgaac ttaatggctt gttttctgtg ctgatgttgg c 221 <210> 629 <211> 475 <212> DNA <213> HUMAN <400> 629 agagaatgta tcttgagcca atgtattaat agtagattgc tttgcttatg tagtaggcaa 60 tatatgggta tacattttcc tgactattat cttaatgact attccaaatt atgactacct 120 taaaaactac caaaatcccc tgctccagaa ttttcagttt cagatgaggt tcataattca 180 tggcctcact tttcccacat tctcctacag gttggacgtg ataagtatga gcctgcagct 240 gtttcagaac aaggtgataa aaagggcaaa aagggcaaaa aagacaggga catggatgaa 300 ctgaagaaag aagtttctat ggtaagtact aggaggaata ttgtattcca tccttattaa 360 aaatccatga tttttaatcc cccaggcctc actgtatctt caaagaactg ctatatatta 420 aaagagatca tagcagctgt acagatctca tctagtcgta gaggttaatg ttgaa 475 <210> 630 <211> 592 <212> DNA <213> HUMAN <400> 630 tttttttcag gttcccacac agtttattga gggagccaaa gccagtgaga ggacgaagga 60 gtcctacttc aacctacttc cttaaagctg tgtgcctcca gcatgaaggg accttcccag 120 agggcagggc ctgccctata aggggccaca tgaagccttg tggagactcc tgcctctcat 180 accacagcct gtcctaccct aaagacccag acatgacagc agacataatc cccaccccag 240 gagggtgctg aggaaacacc cttacccatg cccctcccct agagacctca ggaagaaagg 300 ccaggacacc tgtcctgtga ttggccagtt gaatcctcaa cgtgaagacc tggcaggcct 360 ggctgacagg tctgttcaga tgtggcctca ggcatctact ctaggatcca acccctaaca 420 ttcaaacatg attaaaaaca cccaggacac ttctcttgct ggcagaggcc acaccccaga 480 taatggcagt cctgccaaac tctggccaga gatagggacc caagctgact gggtgtgagc 540 acgtaaggag accactctgc cccatgggga gaatcttcca gggctcagct ga 592 <210> 631 <211> 317 <212> DNA <213> HUMAN <400> 631 tgatacttct gaactggtga ggtgtgctca caatgaggtt tcctcacaat gaggtttcct 60 ctaaaagtta tttttttact ttcttctgtt agcaaagcag ttgccgctac agattgaatg 120 catctgggcc atctgcgggt tactgggtta aggatttttg ataggaaggc tacgggttat 180 cagtggcctc agtgctttca gaatacgccc ttgtttacac tgacaacaaa gtggtattgg 240 agtcttatag ggttatggag aataccttca attatcaatt ataggtttta aatttaccct 300 ggcttttaaa ggaatag 317 <210> 632 <211> 447 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(447) <223> N=any base <400> 632 gagactggtt ttttccagcc ttggtttgga agcttgtctc aaaaaccatt acaaaatctt 60 aaccttcaaa tacattctaa atcactttaa tttagaagat aggtgagcaa cttgagtgat 120 cccaaaccaa actaacagtg ctggtttgtc cgacacccaa agcccacttc acacatttat 180 aaggacagag atttggtaac tcatttgggt attttgtcag ttttaaccct taatatacag 240 gtatcccagc tttgggcaca tgtatgtcca ttcactttca ggaaggggtg tcagtacttt 300 ctttctgtgt ggtgaaaaca taagccatgg tgaactgata atttttgttt ttaaattatt 360 tatattactg aattgggcaa aattacagtt cacactggca gagctagggt tgtccnattt 420 gggccttaaa acaaaccngg caacttt 447 <210> 633 <211> 211 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(211) <223> N=any base <400> 633 aacacacaca cacacacaca cacacacacg tgcacacaca catcccccca caactacagc 60 cgccaaaata accagcatgg ngttgtaaca ttatttctcc atcttgcngt tttctagcct 120 tgagttgggg acatgagtga gaactggggg ttttgaggag taacccttgn gaacacangt 180 actccaggca gccgggnatc ccagatctcc t 211 <210> 634 <211> 388 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(388) <223> N=any base <400> 634 cctaggttgg ccttgaacct cctggcctca aatcattcct cctcagcatc ttgagtaggt 60 gggattgcag ttgtgagcca ctgtgcctgg tcaattttta gttaaacttt tagataagga 120 tatacagggt ttgcatacac aaaaaatgca aataattctt ttgttttaaa tagcttcctt 180 ttccctaaag agattgctgc aagtaactat gtactgtctt atatcttaag tgagctctac 240 ctacttctat tcatgactgt tagttgatac agagtatggg ntttcctaat aagccattat 300 atatttaact ttataggaag gggaataact tgaaggatcc ctgaggatac ttgggggtcc 360 naatttgtag gaaggtgctg ttaaaggg 388 <210> 635 <211> 521 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(521) <223> N=any base <400> 635 ngacaactga ctttctgctt tcacctttgc ttgtcaactc tcccttctcc tcattctctt 60 ttaatgttag gccccttctc cagtcttttc cttttactct ggtcttttac tcgtttttgt 120 atccattttt atttagcccc atcacatcat tgcttaaccg ctgctctcct cccattttcg 180 cttcaccctc tttacagcag cctgtccctc tcccgatctc agtgatgatg ctctaagtgg 240 ttaagagttg attccggagc caggctgcct gggtttgaac ccagatctat ttattagctt 300 ggtgacccag agcaagttat tctgcctgtg actcaatttt cctcaccttt aaactggggg 360 atcatggtta gtttagcatt ttcataggga ttgttgtgaa atttngggtg agtgaatatt 420 tggaaacatt tcatccagtg gnttaggcat atgtagggag agttgggctg tttcacatga 480 ttattncagt cccttagttt tggtccagan ctcatttttt g 521 <210> 636 <211> 386 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(386) <223> N=any base <400> 636 tcataatagc cattctaaca ggtgtgagtt aaagggtctg tagtactctt gcagtgtctt 60 tgctgatatt ctgtgtttgt tttcctgttc tttatttcat ttatttccac tctagtcttt 120 attattnctt cattatttag gagtgttatt taatttccat atatttgtga tttttccntt 180 ctttttttgg tctgtattga gttctacttt tattccattg tggttggaaa acacactttg 240 acntaatcat tttaaattta ttgaggttca ttttatagcc taacatattt gcctgctgga 300 gggatgttcc attanaaccn taagtatgtt acattctggg ccagggcacg gtggccgcac 360 gtctntaaat cccagtcagt ttgggg 386 <210> 637 <211> 317 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(317) <223> N=any base <400> 637 ttggcacagt tgctggtgga ggtccnggct ctggtnggag tgcctccaat tcccttgctt 60 tacgcagctt ctcacgcttt cgctggatgg cagcaacccg ttcacgtact gcacgggcca 120 ctggctggtt aatcggcttc acagaccaag cccagagcca cctggaattg gggtngggga 180 tgaggaacac agcttgggac cccctatcaa agatccatca ggacgccttc ttgggaactc 240 cagtctcgcc tcgggttgca atngacccca actgctcctg tgccnctgca ggtntctcct 300 gcacctgcgt ccanttc 317 <210> 638 <211> 449 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(449) <223> N=any base <400> 638 ggggagaagg tctcactatg ttgcccaggc ttgtctcaaa ctcccgggct catagcaatc 60 ctcccactgt ggcgtcccaa agtgctgggg ttacaggtgt gagccaccac acactgggct 120 ctgctctgcc tttctgagtt tggtttctgc ttatggtggg gagcttgttc ccgttcttcc 180 cacaagaacc caggatgtgg cacagcttcc ctgccgtctt ccttcactca gttggctacg 240 ctncccatcc tagctccact tccagaactg ccttcaccct aggctgggtc cttgttttgt 300 ttttagagac agggtctcac tgtgttctcc caggctggga gtacagtggg cgtgattttc 360 gggttcantg ccaccttcca cctnccgagt ttcaaggcga tttttcctgg ccttcaggcc 420 tncccgagta ggttagggnt ttacagggc 449 <210> 639 <211> 506 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(506) <223> N=any base <400> 639 aaatcgtttc tgttctttta aaattaaatt gtaagacagt tgtttgtcag attttggatt 60 ccatggaaaa agttttgttt agaggtaggt aacacatgaa ctttttaaaa tcaccttaaa 120 taagtagctt cttgcgtaag acaccaaata gtgttccctc ctcatttggg aacatttctt 180 ctgggtactt gactttcttt catatgtttt ttcataataa tagttccagt ttataaaatt 240 acgttctctt ttctagtcgc cgagatgaca tgggaatcat taggatatgt tttgatgtat 300 tttaatagga accagcctgc catggcaagg gctaaagggt aaaccaggac ttcacattta 360 ttcaggtttt tctctctctt ttttaggaat aaaaatatat attgggggga ggntagggtt 420 ttaagggtcc ccttctaggn ctgggggttt ttnccggggt tttaagggnt ttaaccccta 480 ttttacnttt ttaccccttt tncggg 506 <210> 640 <211> 370 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(370) <223> N=any base <400> 640 ttttttttca gctttatctt tttttatttt caaaaatatt tgtttatttt taaaattgac 60 atttaaaatg gtacatattt atcatgtaca gtaccatact gtcagaaaaa cagacacaca 120 gaacaatgga acagaataga gagcccagaa ataaatccac atatttacag ccaacttatt 180 tttgacaagg tgccaagaac acacaaaagg caaaggacag tctctgtaat aaatattgtt 240 gggtacaact gggatatcta catgcaggag gaatgatatc agtctcttac ctttcancat 300 atacaaaant caactcaaac tgggntttaa aggncctgga aactagggna ctactaggag 360 ggnaacatag 370 <210> 641 <211> 168 <212> DNA <213> HUMAN <400> 641 agcctctgaa ccctaggtag agctctttaa atgcttagtc tagctacaga atttgacagt 60 gaatcttaca gtcccacgtg ttactttcta gttatttttg ttattcttgt cttcccaact 120 aaattataag ttccttaagg gcaaggatca catattatat tttattta 168 <210> 642 <211> 143 <212> DNA <213> HUMAN <400> 642 acagcatgga aatatttggg gtagggtggt cattcactct gcttaccact tttggtacta 60 tgtatgtgta cagtgtgtga agtcaagcac agtcacttgc atacgtagag ctactcaaca 120 gtcagtggta aatcatgtgg tct 143 <210> 643 <211> 285 <212> DNA <213> HUMAN <400> 643 gccttcctga gaagatgcaa ccaatcctgc ttctgctggc cttcctcctg ctgcccaggg 60 cagatgcagg ggagatcatc gggggacatg aggccaagcc ccactcccgc ccctacatgg 120 cttatcttat gatctgggat cagaagtctc tgaagaggtg cggtggcttc ctgatacaag 180 acgacttcgt gctgacagct gctcactgtt ggggaagctc cataaatgtc accttggggg 240 cccacaatat caaagaacag gagccgaccc agcagtttat ccctg 285 <210> 644 <211> 132 <212> DNA <213> HUMAN <400> 644 gttcttgaac tcctggcctc aagtgatccg cctacctctg gccttccaga ttgctggaat 60 tacaggtgtg agctaccgcc tctggccagt aagtggattc taaattgctt attgaaatgc 120 aaaggaccta gt 132 <210> 645 <211> 120 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(120) <223> N=any base <400> 645 ccccacccgg ccagaacctt taaatttaaa attgtacagt gtacttgcct ggccaagaag 60 cgtaggacgg angaaggaag taatgttttt acccgtttta cggttaaaga gcttggcttt 120 <210> 646 <211> 219 <212> DNA <213> HUMAN <400> 646 aaagtaaact atgctgtatt aactccatat taggcagcca gtaaaaataa atacaaccac 60 caaaagtaac tcagaaatat gtttaggaaa caatactaat tgaaaaatat agaacttcag 120 gttgtatatc taccatattt ccaatctgta aaatataagt acatttggat caagattgga 180 aaggaagaca aattagaata actcatcaat aacatattt 219 <210> 647 <211> 55 <212> DNA <213> HUMAN <400> 647 agctgcactg cctacctgca agaacttcaa ggcatctaaa cgcaacatcc aacag 55 <210> 648 <211> 263 <212> DNA <213> HUMAN <400> 648 tttagagtac agattttata aacagcttgg cagtgcaggt gaaggtctcc cacaggtgta 60 ttactttgga ccatgtggga aatctaatgc catggcgctg gagctccttg gccctagctt 120 ggaggacttg tttgacctct gtgaccgaac atttactttg aagacggtgt taatgatagc 180 catccagctg ctttctcgaa tggaatacgt gcactcaaag aacctcattt accgagatgt 240 caagccagag aacttcctga ttg 263 <210> 649 <211> 238 <212> DNA <213> HUMAN <400> 649 gcggcggcgt tggcggcttg tgcagcaatg gccaagatca aggctcgaga tcttcgcggg 60 aagaagaagg aggagctgct gaaacagctg gacgacctga aggtggagct gtcccagctg 120 cgcgtcgcca aagtgacagg cggtgcggcc tccaagctct ctaagatccg agtcgtccgg 180 aaatccattg cccgtgttct cacagttatt aaccagactc agaaagaaaa cctcagga 238 <210> 650 <211> 231 <212> DNA <213> HUMAN <400> 650 cggccctagg tcccggcagc ggtggtgacg gcggtgccgg aggttgtcct tggcaggttt 60 tcctcggcgc ttctccatgg aggaggcggt gcgaacggct tcagccccga atgctcgcat 120 ctcccactgg acggcgacga aggcggtggc cgtgcgagcg caggactggg cggcctgtgt 180 gggggtgtga gccgcggtgc ccaaggctgc accggcgagg ggaagccgcg c 231 <210> 651 <211> 376 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(376) <223> N=any base <400> 651 cagaactttc tgcctgggct gccagccccc acttgcctga tacaagatgt acttgatcat 60 gctcaggtgg tcccatggag ttaattgcag cattcttgct cctggaagtg gggttgaggg 120 cccgaggaga agcagaggct gctcggcaga gatcccggaa cactttatcc ctctctcttg 180 cccaggtttt atgccgctga gataatgtgt ggactgcagt ttctacacag caagggcatc 240 atttacaggt gcnggggtga gggcagcggg ggctcttngg aggggaggct ccagccccat 300 catatcttct gaaatgctcc aagcaggatc cccccaactc cagttccttc tctgctggaa 360 atccaatctt tagctg 376 <210> 652 <211> 180 <212> DNA <213> HUMAN <400> 652 taaagtatat tgatgttttt tttattacag ctagtatata tttaagaatg ttagtatagg 60 attttgaata aattttgttt ttaagagaag ttataattta attagatggg gaggaaagtc 120 tttgaagagg aacctctact ttacttttta taaagtgatt ctcctgctca gtctccccag 180 <210> 653 <211> 239 <212> DNA <213> HUMAN <400> 653 agccctttgg aatagcagtg ttccagtgtg tgaacgtgag ttgaaagaac tatgtagttt 60 ggatagctct ccttattttc gttttccagc atgtttttcc gcatggcatc acctgttgtc 120 tagatcttta cttaactaaa ttatggataa aaatacttct ttgttggaag aatttcaaga 180 agggtcttgt aggtcttctc tgacatgtgt ttttgttact aatctgcaaa tcacttagt 239 <210> 654 <211> 334 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(334) <223> N=any base <400> 654 cgggggtgga cctggtttgt ataagtacca tgggtgccac tctagtctcc aggactttct 60 ctagcctaga cctagtaacc actaccagga actgctgggg cncagctctg gttctgtggc 120 atagtgataa caaggactaa ctcgggactt ccaaggaaag ggcgctgtgg tcactgggtg 180 gcagcctcaa atctctgagt cccttcccct tgaccccttg acagtctgtg gtatagctgg 240 ccccagggcc tacttcacag ntgtgtgnaa agagcgtcga angggctggg aatgttgnct 300 gactacactg tctggtccct ccctgccctc agtg 334 <210> 655 <211> 262 <212> DNA <213> HUMAN <400> 655 gaaggcttct caatggttaa aacagctgag ctggaccttc aaagagaagt agcttaccag 60 cagatataga gcattctaag cagaaagaat agcaaggagg gaggcatgca agtgtttggc 120 agggattcag gaaccttgag tcatctctaa gggggctaga gtatagagcg ggggtgtcca 180 agggtcagaa tacagtcgtg ggtgcttagt ttctgtttct ggttgggcca gtaaagcccc 240 ttcctcatcc cggttttcca ct 262 <210> 656 <211> 277 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(277) <223> N=any base <400> 656 ggagccacct ttcaatgacc tcccgcacat aaggtctcag tctacctgta ggaggtcccc 60 tgttcctaat tagctccang aggccaaggg aggagagggc actggccagg gagtctggaa 120 gccagatacc ccttccactg tgtttccata gactgggaag gaaggaggat ggaggggtcc 180 cacccagact gtcccctgag accctggcat gctctgtacc ttgntagcct ggccgaagca 240 gcccttgccc agcacctccc cgtggatgan gtcgacg 277 <210> 657 <211> 361 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(361) <223> N=any base <400> 657 acgtatcagt atttagtcaa ataattgatg agacctcatt acagatcttt ggngctttgt 60 gtgcagttca ctctcctctg atattcagtc ctgcgtattt taacattctt cttccagcaa 120 actctcacct ctgtctcctc aactcagtta gatctgtgga tgctgtttgg gttctctctt 180 ttgttctgta acctggagac tacctccaga cagtaatctg gagcaatcag agggtttgtc 240 tccattgttc cccttctctc agggatcaca gttttgtgct gcctgttgtc ccagtgtctg 300 aaagcttttg ttttacatat atttttccag tattgtagtt ggttatggca gaaggacact 360 t 361 <210> 658 <211> 370 <212> DNA <213> HUMAN <400> 658 atccaggtga acactcattc tggaaactga tcgctttacc caaagttggc cttatagcct 60 tcgtcatcaa ctcactcagc tcgtgttttg gcttcctcga tcctactctg tctctctttg 120 ttttggagaa gttcaattta ccagctggat atgtgggact agtattcctg ggtatggcac 180 tgtcctatgc catctcttca ccactatttg gtctcctaag tgataaaagg ccacctctaa 240 ggaaatggct tctggtgttt ggcaacttaa tcacagccgg gtgctacatg ctcttagggg 300 cctgtcccaa tcttggcata ttaaaagtca gctctgggct gctgggtgct gatattagtt 360 gtaagtgggc 370 <210> 659 <211> 173 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(173) <223> N=any base <400> 659 ctgtagaaaa anaggtctat gttgcccagg ngagatcccg tctcaacaac aacaacaaca 60 gcaacaaacc aacaaaaaac gaaacaaaag antccagata aaacttctag ggacacaaat 120 tatacttgag ataaaaatat gctaggtagg tttattagca gattagacat tac 173 <210> 660 <211> 372 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(372) <223> N=any base <400> 660 agagagaacc caccatggtg ctgtctcctg ccgacaagac caacgtcaag gccgcctggg 60 gtaaggtcgg cgcgcacgtg gcgagtatgg tgcggaggcc ctggagagga tgttcctgtc 120 cttccccacc accaagacct acttcccggt caacttcaag ctcctaagcc actgcctgct 180 ggtgaccctg gccgcccacc tccccgccga gttcacccct gcggtgcacg cctccctggg 240 acaagttcct gggcttctgt gagcaccgtg ctgacctcca aataccgtta agctggagcc 300 tcggtggcca tgcttcttgc cccttgggct tccccccagc ccctcctncc cttcctgcac 360 ccgtgacccc cg 372 <210> 661 <211> 382 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(382) <223> N=any base <400> 661 ttctgcagat ggttatccaa ctttcccggc atcatttatt gaatagaatg ttctttcctg 60 agcatatatt tttgttgact tcatcaaaga tcagttggtt gtaggtatgt ggctctattt 120 ctgggttctc cattgtgttc cattgatcta tgtgactatt tttattttta tactagtacc 180 ttctgtttta gtcactatag cttaggtagg tataattgga aggtcagggt aatataatgc 240 ctccagcatt gttctttttg cttagggatt gctttgacta tttaaggctc ttttttgggn 300 tcccatatta atnttatgga tttattcccc taattctgtg gaaaaatgga cattggggga 360 acncgatagg gggntgccct gg 382 <210> 662 <211> 343 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(343) <223> N=any base <400> 662 atacnaaact atgtcttcaa aagtctgtgt gtattttaca tttatagcgc atctcaattt 60 ggtttagcca cattgcaagt ggtcaatact catttgtggc tagtggctac catattggac 120 agtacagttc tacaggaacc actcaaaaca caattcaccc tgggntagca attttgctac 180 tagtctgcta gtgcttgagt gagctgtttt taaactgctg ttagtgagga ccactaaata 240 ggtgcatctt acttgactcg tgttttccct ctgaggctgt ccngaaggca aagttcagga 300 atttttattt acaggcatga cttggattga ctcaagggtg ggg 343 <210> 663 <211> 560 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(560) <223> N=any base <400> 663 ggagtttcag tctccaactc tcagcccacc aatgaaagcc actctatcaa agccatcctg 60 aaaaatatct cagtcctggc tttctctgtc tgcttcatct tcactatcac cattgggatg 120 tttccagccg tgactgttga ggtcaagtcc agcatcgcag gcagcagcac ctgggaacgt 180 tacttcattc ctgtgtcctg tttcttgact ttcaatatct ttgactggtt gggccggagc 240 ctcacagctg tattcatgtg gcctgggaag gacagccgct ggctgcccaa gcctgggtgc 300 tggcccggct ggtgtttgtg ccactgctgc tgctgtgcaa cattaaagcc ccgccgctta 360 cctgactgtg gtctttcgag cacgatngcc tgggttcatc ttcttcatgg ctgcctttgc 420 cttctccaac ggctacctcg ccagcctttg catgtncttc ggggnccaag aaagtgaagc 480 cagctgaggc agagancgca ggagccattc atgggctttc ttnctgtntt tggggtntgg 540 cantgggggn ttgttttttt 560 <210> 664 <211> 335 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(335) <223> N=any base <400> 664 atatgtttgt tggctgtttg tacancttct tttgagaatt atctattcat gtcctaccca 60 cttttggagg agattgtttt tttcttgctg atttgagttc cttgtagatt ctggatatta 120 gtcctttgta agatgatgat ttgtgaatat tgtctcctac actgtgggtt gtctgtttac 180 tcttctgatt atttcttttg ttgtgaagaa tttttaaaat ttaattagga ncctatttat 240 ttatttttgt ntttgttgca ttngcttttg ggggnctcag gacataaatt ctttgcccag 300 gacccaatgt ccaggaaatg tttttgctag gaatt 335 <210> 665 <211> 423 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(423) <223> N=any base <400> 665 tctgtagcac ttggaattga atttgtgcac aatctaaaac tatagaagga gaaattacag 60 ttggccctct gtatctggat tctgcatctg tggttggttg aatcgaaaat attgggaggg 120 aaaaatggat ggttgtgtct atactgaaca caaagtcttt tttcttgtca ttccctaaac 180 aatacagctt aacgactatt tacgtaggca tttacgtcgt attaggtatt atgagtaatc 240 taggagatga tttaagtata ctgggagggt ctgtgtggga ttatatggca aattcaccac 300 tttatgttag gaggacttga gcctctgtag gattttcgat atccnaggaa cccattcccc 360 ccacaggtgg ccaaagggtg gacngtggcc ntagggtgtt acngttggaa cccgatgttt 420 ttg 423 <210> 666 <211> 384 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(384) <223> N=any base <400> 666 ttgatacaga aatatttctg aaggatttct aatcagaatt gtaaaacaat gtgctatcat 60 gaaatcgcag tcttcacctc atggttcatg gaacatttgg ttagtcccat aaaatcctat 120 gcaaaacaaa gtagttcaag aatttttagg taggtagtca catttataag gtattcctct 180 tactctttgg gctttttcag tctgatttat ttaaattttc atttagttgt tttacttttg 240 gactaaggtg caatacagta gnaggataac ttcgttacat ttatgttgta gggaaactaa 300 ggtgctgtct cctccccctt cccttcccac aaaatctgta ttccccctat tgctgaaatg 360 taacagacac tacaaatttt gtat 384 <210> 667 <211> 446 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(446) <223> N=any base <400> 667 cgcttaacag agcaagtgat gggagccttg ttcctgggtt ctaccatggg agacgctgat 60 cagcaggatn ctggctccct ttcccaaccc actgctccca aggcctccag ggccntgtgt 120 acataaactg gtgggttgga agttgctggg taactctnat ttcagacatg cgtgtggggt 180 accttttctg tgcatgctca gcctgggctc tgtgcgtgtg tgtgtttcta tgattntaga 240 agggtaccag gcacaggttc tgtcctaagg gcacttacca tttagtangg gagatggaac 300 caacccaatt aactctagca atagcctccc taacctgggc tcctccattn gattcagtga 360 accttccaat gcatggctca taatttcaaa atacaggctg gttagttact ccctacctng 420 aaagccttca taaggtgcct ctttgc 446 <210> 668 <211> 467 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(467) <223> N=any base <400> 668 atgctgtcat caccagtaag ataccccagc ccggttggct aacccctagc tcagccctgt 60 ttgtggttag gggagttcta gacagaacat aattagaccc ctgctacttc ctgaaacctc 120 agctaggact gcagggaggg gtgcgaggct agccacgcag gcggggccct gggtcatttt 180 aaactctcag agtgaacgtc ttgataggac cgacaagacg catgacatgt acttagaaag 240 cttatcttag agccacactg agattggaac ccgcaaaata tgccaggaaa cgccacccca 300 gtgaccacca ctgnnccgcg cagggccgtg gggctgagcc acgctctcgt tttgtcaggc 360 agctatgcag ttgctcttcc ttgtttttgt tttttttttt ttttgttttt aatatttatt 420 tttttagaga cagggcttnc ctgttgcctg gnctggagaa cagtggc 467 <210> 669 <211> 430 <212> DNA <213> HUMAN <400> 669 cgtacatggc acgtggacct gcatagacac gtgtttggtg gaggctgtct tatacggatt 60 ctgcacaact caagtcccct aatgggaaca gacttgggga ggtcactctt gaggcttttt 120 gtggtattgt ggctactggg agacctgagg agggttctgg tcactagcag actcatttca 180 ttcacccctt ggaatctgcc caggacttgg acttctgtgt aatagtaact tcacgcccca 240 atgatcctcc acgttccttg ctgatgctgt gattgctcct ccaagttctc cacctatgtc 300 catctgagca cttggtattt ctactctagt gtcaaaaggt cctgttccca agtctcctcc 360 caaacattta ttccaattta tcatccagat gcccgtcctt tgccatccct ctctgttcca 420 gcaaaggaca 430 <210> 670 <211> 546 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(546) <223> N=any base <400> 670 ccangtgaag aggtcattat tcgagacagc cctgttctcc ctgtcaccct gcagtgtaac 60 ctcacctcca gctctcacac ccttacatac agctactgga caaagaatgg ggtggaactg 120 agtgccactc gtaagaatgc cagcaacatg gagtacagga tcaataagcc gagagctgag 180 gattcaggcg aataccactg cgtatatcac tttgtcagcg ctcctaaagc aaacgccacc 240 attgaagtga aagccgctcc tgacatcact ggccataaac ggagtnngaa caagaatgaa 300 gggcaggatc acctatgtat tgcaagtcag ttggctaccc ccacccagac tggatatggc 360 gcaagaagga gaacgggatg cccatggaca ttgtcaatac ctctggcccg cttcttcatc 420 atcaacaagg aaaattacac tgagttgaac attgtgaacc tgcagatcac ggaagaccct 480 ggcgagtatg aatgtaatgc caccaacgcc attggntccg cctctgttgt cactgtcctc 540 agggtg 546 <210> 671 <211> 411 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(411) <223> N=any base <400> 671 actttaaata cttcactgta ctctcttctt gcttgcatgg tttcttaggg gaagttggat 60 ataattttta tttttctcta tacgtaaggt gtttcccccc ctccccagct tctttcagga 120 atgttcttta tctttttatt ttctgtagtt tgaaaatnga aatgcctaca tgtaggtttt 180 gggggcattt atcctgtttg gtattctctg agcttcctgg atctgtggtt tggtgtctga 240 tattaattct gggaatttct cagtcacttg tttcaaatat ttcttatatt attttgtttc 300 ttctctttct ggtgttctta ttacacatgt tacacctttt atttatttta gagacagggt 360 ctcactctta cccaagccgt tctcccacct cagcctccca aataatcggg a 411 <210> 672 <211> 441 <212> DNA <213> HUMAN <400> 672 gctgaggctg gggctcgggc tggggccgcg ctgcgggagc tctggggagc cggcggcccg 60 gccattgcgc ccctccccgg cgagcacacc tgtgtggggc tttccccccc gccccggacc 120 cttctgggct tgatagtgtt ccgggggagg ctggagggtg ttgggggagg acggagaggt 180 catgggagtc cccgctctgc ctcaaccacc tgacccaggc tcccccggtt tctctcctcc 240 ggcggtcgcc cgcgctcggt ggatgtggct ggcagctgcc gccccctccc tcgctcgccg 300 cctgctcttc ctcggccctc cgcctcctcc cctcctcctt ctcgtcttca gcttctagaa 360 ggggggggag agggtgagaa cgagaatgtt aatcccaggc agcctcgctg acttctcccc 420 gcctgctcca gcccaggggc t 441 <210> 673 <211> 293 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(293) <223> N=any base <400> 673 acttctatca cttccttttg attttttctt atagcttcta tctctgctta cgtcacccat 60 cattcttgcg tgttgtatgc ttttcgcatt agagcccttt gcatgttaat cagttatttt 120 aaatttatga tctggtaatt ctaaaatgtc tgccataact gagtctggtt ctgatgcttg 180 ttttcttttc agactgtttt tttgtctttt agcatgcctt gtaatttttt gntgatagct 240 agacatgatg tattgcataa ataaaccagt aaactaaaaa aaaangcaaa tta 293 <210> 674 <211> 262 <212> DNA <213> HUMAN <400> 674 caggaagaca ggtaaattac ccaacctcac acgttaagtc agaactggga gccataattt 60 tgtatccctg gtataaatag acaatctctc gaagaaatga agagatgacc atagaaaaac 120 atcgagatat ctccagctct aaaatccttt gtttcaatgt tgtttggcat atgttatctt 180 tggaatttag tgtctgagcc tctgtctgtt actgtagtat ttaaaatgca tgtattataa 240 tcatataatc ataactgttg tt 262 <210> 675 <211> 251 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(251) <223> N=any base <400> 675 gaaacccact acggcccaga tgggcagcca gtggtgctgg cccccaacca cacggatcat 60 tgccactacc aagggcgagt aaggngcttc cccgantcct gggtagtcct ctgcacctgc 120 tctgggatga ntggcctgat naccctcagc aggaatgcca gctattatct gnntccctgg 180 nnaccccggg gctccaagga cttntnaacc cangagatct ttcggatggn gcagctgctc 240 anntggaaag g 251 <210> 676 <211> 187 <212> DNA <213> HUMAN <400> 676 aaaaaagtta aacacatgac attggacctt atgaaatgtg tttaccctag agctgttgat 60 tgtatgatag gtccctccta gatagtattc aaggtttaat gcagaaacag agcaagactc 120 tgtttcaaaa ataaaataaa ataaaatagc tggccatggt ggcttgcacc tatagtacca 180 gctgctc 187 <210> 677 <211> 212 <212> DNA <213> HUMAN <400> 677 ggcagattga tgacatactc agtgtggcct ccgtgcgtcc agctgtcttg ccacccatac 60 ttggctcaaa atgagctaat tgcccactgc caagcacgtg gcctggaggt aactgcttat 120 agccctttgg gctcctctga tcgtgcatgg cgtgatcctg atgagcctgt cctgctggag 180 gaaccagtag tcctggcatt ggctgaaaag ta 212 <210> 678 <211> 219 <212> DNA <213> HUMAN <400> 678 tgttctctga ctattctttt gtttatcatc ttgctctttt tatgcgaata gtcattcttt 60 tatctctgaa gatagaaact ggaggacatt tgggaaggga tatgtcctgt gcattgtttc 120 ttttctcttg cctattctgt tcgcgtattt aatgttgaca cttttctcca atggcttgag 180 atacatggat gtctgctttt tattttaaga gcaggccac 219 <210> 679 <211> 442 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(442) <223> N=any base <400> 679 gagacaaggt agtggaagtg tgtccctccc attcactgac caaggtgagg ggactctagt 60 cctttgctgc tgaccttcag cctcccttcc tcttaaaaag aggtcctagt tggggagcga 120 tggctgaaga gttaccataa aataccaagt aggnnnnnnn nnnnnnnnnn nnnnnnnnnn 180 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 240 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnngtagggc 300 catttagtat ggtttcatct ttattaaaag tcttaagttt tagatttttg aagttatcac 360 caataaaata tccagttgtg gtcttgtgtt gagtgaaaat gttatttaaa tgcagatatt 420 taaaatatac tacaattttt gt 442 <210> 680 <211> 395 <212> DNA <213> HUMAN <400> 680 cgcctggtta aatatttttg gcaagagtac ttcataggcc accctcaaaa tttcagcatc 60 actcgtacca agtatctatc acaaggcagc atgtgtctac atctccaccc cagtgctgtt 120 acagtgggac agtttctagt gtattgtcat tgcgaccagg cttttaagat tcttagcata 180 tctgtaatat ccacatgcag atgtagaatc caaatcgtat ttacagagaa ctttgcatgg 240 cagcttttat atggtagtga tacattcagt ttcttacatt ctagattatt cagggaggtt 300 ctggagttgg acagatttgg ggttaagcct gatggctagc tgtgtgacct tacacacctc 360 gcttcatctg tttcctatgg gaatttataa tagta 395 <210> 681 <211> 446 <212> DNA <213> HUMAN <400> 681 gggggctgag gagtttggaa aatcttgctg tcagtaggga gccattgagt gttgagttgg 60 ggtgggggtg ttatggttgg cacatttgca tagttactga ggacaggtta ggaggggccc 120 ctttctccct aatgccctac actgttccca accattatag tgaagctctt tgaggtgatt 180 gagactgaga agacgctgta cctggtgatg gagtacgcaa gtgctggtga gccgcccacc 240 ctctccgccc tgcccctgtg ccacctcccc ctgccgctgc acctgaccct gaccccgctc 300 ggcctctgcc ctgcaggaga agtgtttgac tacctcgtgt cgcatggccg catgaaggag 360 aaggaagctc gagccaagtt ccgacaggtt ggggcagggc tgagggtggg gctgactggg 420 tgcctgggtc cctgggaggg cgtctg 446 <210> 682 <211> 281 <212> DNA <213> HUMAN <400> 682 aaaacaaaga aagaaaaagg atgattactt gaagtggtac aaatgacaac caggtaccaa 60 gaaaacagtg agtttgggca agtgtaattt tttagaactc acagtatatc tagaatggga 120 tgaaagggaa gaagatatag gatagtctca ttcatataga aagttatcct aaaatcatgt 180 aacaaagagg ttataaaaac cataaaatca tcacgaaaaa tgacagccac tagccctgaa 240 tgctgatgta gaaaggacat tgatgagaat aaaccttctg t 281 <210> 683 <211> 265 <212> DNA <213> HUMAN <400> 683 cagggactga ccgtgagcct gggtgaaagt gagttccccg ttggaggcaa cagacgagga 60 gaggatggaa ggcctggccc ccaagaatga gccctgaggt tcagggagcg gctggagtga 120 gccggcccca gatctccgtc cagctgcggg tcccagaggc ctgggttaca ctcgcagctc 180 ctgggggagg cccttgacgt gcctcagttc ccaaacagga accctgggaa ggaccagaga 240 agtgcctatt gcgcagggag aggaa 265 <210> 684 <211> 232 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(232) <223> N=any base <400> 684 ttgattggat ctttgaaaag tagaagttta atattagttg aaataattca ttattgcata 60 actttctatt ttgatataat ttcaggctta tgtnnnnnnn nnnnnnnnnn nnnnnnnnnn 120 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn gtggaataat taatttttaa 180 ttaactttgt taggccagtc cctgagacga ataggacctt gtccctggat ga 232 <210> 685 <211> 251 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(251) <223> N=any base <400> 685 anaaaaatta ggttggngtc ctggaacatg gacaatggct atttcttccg gtaattgaag 60 attattaaga acatgaacaa ctagtgtttc atgagcaagt tccttacctt tactgttaaa 120 tagttctcgc tcagcctaaa tttttccaaa tgtatgagat actctgaaag catatttaga 180 gtcagtatag atagttccta cctggttctg taaatatttt agggcctaag tgcgaataac 240 ttgcaagctt g 251 <210> 686 <211> 268 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(268) <223> N=any base <400> 686 ggtgttcgtg tgaaagggta ttgcccttta cacgtgtgct tggttttgcc tttcctatng 60 tctaacacgc tcaccgtgnt ttgcatgcta gtatgntata cangngntgn tgnattatgn 120 tgatttgcat gctgtcttac atgcatgctg ctgcattgtg ttacacacac gagtccatat 180 gttacatgtg ttacgtgctt atttttacta ggtatttatg tttgcatatt atatgtttct 240 gtgtgcatca gcatatcatg gcacatgt 268 <210> 687 <211> 328 <212> DNA <213> HUMAN <400> 687 acggtactgt tttctgtggg acatctgttg gtttttgaga agcacctgct ggcactgacg 60 gcagtcttgg ggaacacagg tgctcctgcc agagtcctca ccttctgctc acattgcaga 120 aggccccctg ctgaggccgg ctggccggag gaccaccccg cagaccacgc gcccggggcc 180 tggcaccaag agggaggccc cgatcagaag ggggagcgga aaccttatta agcttgccca 240 tttcgccgtc gctctggtca tcatttaccg caccctgggg cagctcctgc ccgagcgcta 300 cgaccccgac cgtcgcagcc tccggttg 328 <210> 688 <211> 59 <212> DNA <213> HUMAN; CGGAAGTACCAGCTGCGGGAAGGAGCTGCCCACTGTGCGTCTTCTCAACTTGTTGGGACA ACCTTCCTGCGGAAAGGAGAGACAACCTTCCTGCAGAAAGGAGCTACCTGCTTCAGGTCT ACTGAGAGCTGTTCTGCCACTCAATAAAGTCTTCTCCATCTTGCTAGGNCTCCATTTGT <3721604H1;DNA;HUMAN <400> 688 acagagcatt aagtgcctct taaacttggt ctctctggtt ctgtgggtct ttttggaat 59 <210> 689 <211> 216 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(216) <223> N=any base <400> 689 gcagcccttc ggaaaagtgg ccagactgtt agggtgcctg ttcccatatc tcctcaccag 60 gcaggtcctc caggcctggg cctccaggaa tcncctgcca gagcaattga gtctgtagct 120 ctgctactcc ctggtcagat cccccagggg caaatgaaag cctctctgcc actgtctcta 180 cagtggaatg cccttgctac ccttggataa cnaagg 216 <210> 690 <211> 293 <212> DNA <213> HUMAN <400> 690 gaaggagggg gggaacgaaa caaaggaaaa aaatctaggt ctgcacacaa agaactgctg 60 ggtgaacggc tgtgggcatt tcatggaaat attgcccgct ttcccccttt gaatgcttac 120 ctggcaggag tcgactttgc cttccaggaa gcctgcgcag atcatgcggt ctgtgaggga 180 gaagttgtag agcacactac aggttttctg gtctatgatg cccacggacg ccttctgcag 240 gagctcgggc ttggtggcta ccagggaaag agccagaaag gccacgtgca cag 293 <210> 691 <211> 270 <212> DNA <213> HUMAN <400> 691 aaaaaccccc aaaaccaaaa ccccacaaaa tcagaggctc aagatgactg atgtgaaggg 60 agtggcgttt aagaggccat ttattttgat gacgcagctg cccaggaaca gagaacatgg 120 gagaaggcat agactgacaa ttaggaggag gagaacactt tggaaggaga ctcttatttt 180 ggtggggcag ctgctcagga acaaaggttc ctggtagggg ggcgcaacct gcgggatggg 240 atggagggta ttctgaccaa tgtccctggc 270 <210> 692 <211> 260 <212> DNA <213> HUMAN <400> 692 gttaaaatga aatccagcgc ctttattttg gaaattccat cttgatttga tatttgggat 60 atataaaaaa tgtggttgta atacatctga tgaaatttaa acatcaaaca tactgaagac 120 caaaatgaag ttggaaaggc attagctaaa acaattggca tgtaaataag gatcttagta 180 gtgaattttt tccttggctt tcttcttgat agagttcatt tagaaaactg agtgaactaa 240 gaaattgttt ttgtttgttg 260 <210> 693 <211> 211 <212> DNA <213> HUMAN <400> 693 gctggccagc cacgagtgac cctgctgccc acgcccaacg tcagcgggct gagccaggag 60 tttgaaagcc actggccaga gatcgcagag aggtccccgt gtgtggctgg cgtcatccct 120 gtcatctact acagtgtcct gctgggcttg gggctgcctg tcaacctcct gaccgcagtg 180 gccctggcgc gccttgccac caggaccagg a 211 <210> 694 <211> 271 <212> DNA <213> HUMAN <400> 694 caggaggaag agagaagccg gtagtggctc agttctagtc caaaaggctc agaagtaggg 60 aagttgacag tgcagccttc agcctgtggc cagaggccta ggagcccaag gcaggccacc 120 agtgcaagtc actgagtcca aaggctgaag aacctggaat ctgacgtcca aaggcaggag 180 gaaccacagg agaaagacgg aaaccagaag actcagcagg ccagcacatc cctccttctt 240 ctgcctgttt tgttctagcc gcactggcag c 271 <210> 695 <211> 354 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(354) <223> N=any base <400> 695 caaaaaaaca aaaacaaaaa caaaacaaaa aaaaaacctc agatttcagg gcctcaagcc 60 tacagttttt aggtcaaggt gggatnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 120 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnactcttg gggacccctc cctttacaaa 180 aatgggatgg acatttgagc caagccagac taattgtcct tatctggtat tgtgtcatac 240 tggaattagg aaaagcagcc cttggcttca actggccata taccataagg acatgagacc 300 taaagtgcca tgtactcctg ccatgcagag aagccagatc aaaagaatct aaca 354 <210> 696 <211> 250 <212> DNA <213> HUMAN <400> 696 aattttttga tagagacaga gtctcactat gtagcacagg ctggcctcaa actcctgtgc 60 tccagttatt ctcccacctc aacattaagt acatttttat taaactattc ctaaattaga 120 gctccagttg ggttggcaga agggtccaat attttgacag agaaatctta aagttatttt 180 gatagatgta tgaggagagg ctttaagagt gtctatactt ctcatgaatt ggaaagaaat 240 actttctctg 250 <210> 697 <211> 223 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(223) <223> N=any base <400> 697 gaaagagtag tctcatgttt tcctcaagaa ccaagatgaa tagcaatana attgcttcca 60 aaatgggttc cttctcccaa tcagattctg tagctcttca ccaaagggaa catgttgaac 120 tgcttagagc caggagatta gccaagtcac tggccattct cttaggggtt tttgctgttt 180 gctgggctcc atattctctg ttcacaattg tcctttcatt tta 223 <210> 698 <211> 229 <212> DNA <213> HUMAN <400> 698 cctccctccc ctccatccct ccattcccct ccatcccttc atcccctcca tcccctccat 60 ccctctatgc ccctccatcc cctccatccc tctatgcccc tccatcccct ccatccctcc 120 atgcccctca ccaccacctg agggtctccc accccctcta ccactctgtg tctcctctcc 180 caccctcttc cctggagggc ttacagccgg ctgtgcttcc aggagccct 229 <210> 699 <211> 181 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(181) <223> N=any base <400> 699 gtcagaagga ccatgaagag agagaagagg gcagagccgt gcatggggct gctccccagg 60 acctgagcag gaacctggag ttttcaggtg agaggctcac ctgtgagcag gatacctgcc 120 tgctcgccta ttggnctcca nnttgactag ctacctagct aacatctttc ctagtacctg 180 t 181 <210> 700 <211> 250 <212> DNA <213> HUMAN <400> 700 tgacaacttg acttctctgg ggactctgaa cttccctggt cgaacagttt tttctaatgg 60 ctattcaagg taagatcagt gtttttctgt ttcttaagaa tggtacattt aaggtagatt 120 aatagatgta aatcttcatt gatttatatg tgttctctaa agattcatgt gcttttttat 180 atgaataagt ttaagtggcc ttttgaaagt aggaaaggta gacaacctaa gtgacatctg 240 tacgtaacca 250 <210> 701 <211> 262 <212> DNA <213> HUMAN <400> 701 aaaggttagt aggaaatgtg ttttccccca tggggcattc ctggagaaat ctctagcaat 60 aaaggtactt gtttgactgg acaagttgta aaacagttta ataaggtttt ttttaggtgt 120 catagcatta ggcaaagcta actgaattga ctggattgtc atagtcaaac atattgcaga 180 tccgcttcca atagaagaca atgaaatagt cactggaaag cctgtgctcc taattttaga 240 acctcatgta tcttctgctc ct 262 <210> 702 <211> 175 <212> DNA <213> HUMAN <400> 702 gtatatttta tatattatac tggaacagct cgtgcccttg gtctcttgcc tcagcacctg 60 ggtggcttgc cgcccacaaa ctgctcactg ttcaattacc attttcagaa tgctttttat 120 gtttgtttga tgaattcata aagtctctaa tgtgaaataa gccaagcaca gaaag 175 <210> 703 <211> 206 <212> DNA <213> HUMAN <400> 703 ttgcataatg aaaatccaaa gtaaaactac aatgagaaac tattttatac ctattaaata 60 ttttaaaatt taatgctaac aagattaggt aaagttaata ttcacatgaa attagtagag 120 ctgcttttga aagcagaatg gtagttcatg tcaagagcta tggtaaaaat tgacatttca 180 ttatcctaag ggagtgatta agaaga 206 <210> 704 <211> 78 <212> DNA <213> HUMAN <400> 704 tttgaggcag gactggcact ggggtggggg catggtttgg ggttacctta aggaccctgg 60 atatttctca gataggac 78 <210> 705 <211> 222 <212> DNA <213> HUMAN <400> 705 cgctgggagt cggctgcccg ggctgcgcgg ggaacctgga gggcaggagc aggcgggagt 60 tgttgcttcg gggcgcaggg tccagacctt gccgagaccg gcgttgggag ctagcagaac 120 cgggaagagg ctcgattgtg tccggtgggg ccgccgggag cctcggcgac ctttgtctcc 180 tgcctggctc ctgcactgga gtgtgacccg gggcgctgca gc 222 <210> 706 <211> 206 <212> DNA <213> HUMAN <400> 706 agtgcaggag tgagtaggtc ttttactgac actactctca gtgaggctca gcattcaatg 60 tctatagatg cttaagcagt agtaagaaag gtataagaaa gcagccagaa atcataatga 120 gagctctttc ataccattta tagcgtcctc atgtcactcc taatgttata atttctctgg 180 ttatattaga gaatcttaaa gattgg 206 <210> 707 <211> 243 <212> DNA <213> HUMAN <400> 707 aatacaaaga caacatgggg ccagaactcc agaaaggatg ctgactttaa gaggactcag 60 ccacccatct cagagagcac ttcagaggat ccagtaaggg tcagaaaaga cagtgtaagc 120 tgatatttat ctaatttaag agatgcaagc tcaaatgcct tcctggggca tacaagaata 180 tgtataaaag aaaaactgca aatgtgatga taaaaggcaa ctgacttcca ccctcagttt 240 gag 243 <210> 708 <211> 163 <212> DNA <213> HUMAN <400> 708 tatgaaagac atctgttgtg ttttgtatgt gcacatattg agagacatcc ataaactgaa 60 tagttgtaat attcagccat tctaaaattt atttttaacc acgttactga ggtatgattg 120 acatacaaaa agctgtacat atgtaatgtg taaacttgat gtg 163 <210> 709 <211> 246 <212> DNA <213> HUMAN <400> 709 ggtattttaa aaaactgtgc acgttggggt actagaaacg taatgggctt tggagtacag 60 cacacctggg ttggaattct ggttctacca ctttctgtgc agccttggcc caggtagtta 120 atctttcagt gcaagcagtg ttgtcattca taaacatgga ggtgatgcgg atcatgccag 180 atatgctatg gacattaact gatctgtgat attaaagcat agtcactggt acttggggtt 240 acctaa 246 <210> 710 <211> 149 <212> DNA <213> HUMAN <400> 710 tgggtgtggg tttagaggtc cccaggcggc ctccccctga acgtcccagc gcccccagag 60 caggtgtgcg agcactgatg ggatttcctg catttctgtg ttaagggaaa cagatggcca 120 agcctcgggg ggcagtgatt ctgggactg 149 <210> 711 <211> 570 <212> DNA <213> HUMAN <400> 711 gctctgtgaa ttcccaaaac agcttgaagg ggcaccgtgc cctggttggg gtggggtgag 60 gggcccagtg actcttatgg ggccctcagg ccattccctt catgggaaat ggcagccaag 120 agcatcacca agaatgactg gttcacgtcc ttgctcccag aactttccgg ggctctctgg 180 ctgaccacag gccaagttcc agacccctct gggtggggat gctgagtcag ggagtgaggg 240 gaccagatct gggttttgga agggatggga gggagggagg tggaaagcag ggaggcctgg 300 gagagacgct gagcagtggc tgagggtgtg gtgcaggaca gcaccttttc ccagaggatt 360 ctttcggcgg gggttggttg cggggtggtg ctgcccagtt tctctcaaag tctgccatcg 420 gtcaccagcc ctgggagctg gcaggggctg gggagaagga agagggagga tgttgcccag 480 aatcgccccc acatggccaa gcagttgcct gtcacctcct cttttctccc tcttcagatc 540 ctggtgaaga ccatgatacg taaacgctcc 570 <210> 712 <211> 275 <212> DNA <213> HUMAN <400> 712 cagcaaccct ggtgaagaag gttgaatttg gaactgacac acttaacatt tacttggatg 60 agctcattaa gaacactcag acttacacct tcaccatcag ccaaagtgtg ctggtcacca 120 acttgaaacc agcaaccatc aaggtctatg actactacct accagatgaa caggcaacaa 180 ttcagtattc tgatccctgt gaatgaggat aggagctgga aactcagtta gtcctctgtg 240 acattactgg agggtggaac attcttctgt cgctt 275 <210> 713 <211> 242 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(242) <223> N=any base <400> 713 ccctgggctg ctctgcaccc ggacacttgc tctgtccccg ccatgtacaa cgggtcgtgc 60 tgccgcatcg agggggacac catctcccag gtgatgccgc cgctgctcat tgtggccttt 120 gtgctgggcg cactaggcaa tggggtcgcc ctgtgtggtt tctgcttcca catgacgtcc 180 tggctgccca gcactgtnta ccttttcaat ttggccgtgg ctgatttcct ccttatgatc 240 tg 242 <210> 714 <211> 297 <212> DNA <213> HUMAN <400> 714 gggctacttc acctcccttt ctatgtctgc ttcaggaagg aaagaaagga gaaataaggc 60 ttagggctag aatcaggaaa taaaggcttt cccagaaacc tccacacttg tgcttaggtt 120 gtattagaca gaactgtgtc acatagacac tgctacttgt aagagacact gggaaaccat 180 gtctagcact tacagcctcg aatgttcctg ctgtcctaca ttcaaagaca ttactctgta 240 catattaacc ttcactattc agatgaacta caactggaac tggatctagg atatagg 297 <210> 715 <211> 265 <212> DNA <213> HUMAN <400> 715 gcgagtctcc ggtttccgcc cagtctctgg ggacgcggtg gcggggtctg aatcgcctgg 60 cttccaggga gttttgggcg ggtccccgca cgggagcgtg gcaggcgctg gactcgacag 120 cagatgtgga actggagagc ttggcgcgcc ctcatacttt gtcacacacc tacgccacca 180 gactggggtc gggcccctcc gcgttctgct ctggagggcc tgggtctggg cccagcatag 240 cgcttttaga atctcctcag ctgaa 265 <210> 716 <211> 167 <212> DNA <213> HUMAN <400> 716 ctgcctttat tatttttgtc gcgttattca aaatcagata actgtatgcc tattattatt 60 aagatagggt cttgctatgt tgcctaggct ggccttgagc ttgtgggctc aagggatccc 120 tctcatctta gttttactaa ttactaaggg cacagaccct tgccact 167 <210> 717 <211> 214 <212> DNA <213> HUMAN <400> 717 cgcagcgcag actatagttt cttaaggaag attttcttaa atggggattc accgacccag 60 gcatctagtc cattcttcca gtgtgggaag tatttatttt ccttgaaagg aagtctgtac 120 ataaatggat tctgagaaag ctgtgctaga tctgccgctg cttttttggt tttgggtttt 180 tttgagcctg ggtgacagag cgagactcca tctc 214 <210> 718 <211> 253 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(253) <223> N=any base <400> 718 ctggggcagg caccaggctg tcttcagata cttcatacag aaatggtatc tccctgaccc 60 ttttctgcga tttgcctcat ctgtcttcat ctcatcaagg gtcaggacgt aggagccgac 120 agacccagca cctttctgag tctgtcctgt ccaagtgagg gtgactgggg gcttgttctt 180 cttctcagag cctccctgtg gngttctctt ccctccttca gcctgtccat caacacagca 240 ttgcgggatc ctt 253 <210> 719 <211> 140 <212> DNA <213> HUMAN <400> 719 taagaacgcg gggagatgga ttttcatgcc aatcgttccc cagcgaccca gactcagacc 60 ctggggcatc gggtgtgtgc atagaggggg cagtatatgg gaagggctca atcaggtggc 120 tccacggccc aggaaagagg 140 <210> 720 <211> 60 <212> DNA <213> HUMAN <400> 720 attcagcact ttattgtaaa ataggccttg tgttagaatt caagctgtct aaaccacctt 60 <210> 721 <211> 182 <212> DNA <213> HUMAN <400> 721 aagattttca agacgaactg tgatttgggg agggatggcc atctcagtca actttaactg 60 ataggaggta caacaaattt atagttctga actctgcacc tggagtctgt ctaccgaaat 120 caaaccactt gctgaccagc ataaaaataa ataggaaaat atttcagtgt tttccacaca 180 ac 182 <210> 722 <211> 112 <212> DNA <213> HUMAN <400> 722 gagctgcagg gtctggcatc agctctgtgt cttttccatg gccccaggct ggctcaggtg 60 tgagctgaag aggcaaaact gtctgtttag gttgcattgg gttcccctga aa 112 <210> 723 <211> 169 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(169) <223> N=any base <400> 723 tgcatgcata cgcaaggcag tttgatccca gtgcttttct ttttagcaac tatannnnnn 60 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnntc 120 agatcttaga atctttgcat ttaaaaatgc aaactgattg agcatctga 169 <210> 724 <211> 238 <212> DNA <213> HUMAN <400> 724 ctctgagccc atggggaatc ttcttatctc agcattgcag aattcagaat ccacggtaac 60 ttttcatgtc attttgactg cttgtcatgc atgcacttct tttttagatt tctctcatga 120 aaagtgttga caaatattcc ttttggaaag agctcacttt tccattacac tggttctaag 180 tatcaggaat atatcagagg acatttttat ccacttgtgg gatgcatcca catggcta 238 <210> 725 <211> 290 <212> DNA <213> HUMAN <400> 725 cataacagca ttgtggatga tgagaggatg aagtccactg agtacatcag cacaaaggaa 60 ttcaccagca tcaggatggt cttggtggcc attttcacta gagaagtcct taatataagg 120 ctgctgctgt gaaagtgctg ggagtgcctc tgatgcctgg acaaaagaat gaccatgtat 180 acacttgaga gcagcgtgat tcctatgaag aaggcatctc tggataatga gagcataaga 240 aatagcgtcc tgatgaggac attcattggg aaaaatgtgc aatatttgct 290 <210> 726 <211> 146 <212> DNA <213> HUMAN <400> 726 aaattggctt gatgtaattc tgttccatag aaagaatttt agataagact tttttaaagc 60 tgagcccaac tatgggtttg taacctcaaa tacatatgag ttgggtaaat ttctttcctc 120 ttgaggtcca aaataacttg gggctc 146 <210> 727 <211> 147 <212> DNA <213> HUMAN <400> 727 gaaaatcacc ttcccgagga gcaggcgtgg tgcagaccca caggggtttg tggcgggagt 60 agagggtctg tttggggcga gataagagac tgaacggcag agtagggagt gctggctaag 120 gcagtgctgc agagcgaaac tctagac 147 <210> 728 <211> 153 <212> DNA <213> HUMAN <400> 728 tttaataggt gggatgtggt gctagtccaa catgtgtggg aaatggaaca actttaaaat 60 attctatttg gggtttcaga tattggtatt tacaagacat gtccatattc taatgtagat 120 atcaaaacag tcgatacagg ccaacatcaa aat 153 <210> 729 <211> 283 <212> DNA <213> HUMAN <400> 729 acattgacag ctttgaagag tgcagcctcc agtcagatgg ctctgaggtg ctcctgagtc 60 ctgaagtcac ctgtggtcct ccagacatga tcgtcaccac tccctttgca ttgaccatcc 120 cgcactgtgc agatgtcagt tctgagcatt ggaatatcca tttaaagaag aggacacagc 180 agggcaaatg ggaggaagtg atgtcagtgg aagatgaatc tacatcctgt tactgccttt 240 tggacccctt tgcgtgtcat gtgctcctgg acagctttgg gac 283 <210> 730 <211> 201 <212> DNA <213> HUMAN <400> 730 tgggagagag agtatctagg aggtacctgc gctttctccc caccacggta agtaacgtgc 60 catcattctc ccatttcaca gagggcagac tgaggctctg aacgcggaag ttcttgcaag 120 atatcacgca gcagagcagg gatgtgcacc agatctcctg actttaaaaa gcaccaaaca 180 tagtgattaa gaacaaggac t 201 <210> 731 <211> 337 <212> DNA <213> HUMAN <400> 731 aaatgaaaac tgaaagaggc tcaggtcacc gacttagatc ccaccatcag tcagatgcgt 60 atgtggtgcc aacgctgctg gatgctccaa ccctcttgtc ctccgagctt tgggcttctt 120 cggcccactg ccctgtggct cccatcacct cctgctgtgc cgtggagctg ggcttccctc 180 gcccggggcc gtgtccagct atccagccca cactcagcgc tgtatgcgga tgctgctgcc 240 ttcagtggtc ccaactgcct gccaaccgtc ccaggtggag ccttgctgct ggcggctctt 300 gtggttgggt gctctcgaag gttactgatt cggaaag 337 <210> 732 <211> 180 <212> DNA <213> HUMAN <400> 732 gggtaacaga gcaagactcc gtctcaaaat aaaataaaat aaacattgta tatacttttt 60 taccagtaaa tggtgaaaat atagatgaat tgggtggttt tctaggaaaa tgtaaattac 120 caaagtgact taaggtggga caggaaacct gaataaaatg gaaaagtagg gaagaaactt 180 <210> 733 <211> 199 <212> DNA <213> HUMAN <400> 733 ggggaaacgg aggcatgggc agaggaactg agctgtacct ggaagtggaa gacgcctgcg 60 tagccatgct ggaaatcctg tccaggaggg accacccggc gcaggagccg gggatacaga 120 gtaagggagg cggcggcggc aaggaaccag cagttacctg ggaggagagg ccaggattag 180 gtgaggatgg aaggaggga 199 <210> 734 <211> 70 <212> DNA <213> HUMAN <400> 734 atcctcattg ctactgccct ctgcgctcct gcatctgcct gcccatattc ctcggacacc 60 acaccctgct 70 <210> 735 <211> 412 <212> DNA <213> HUMAN <400> 735 gccaccacgc ccagcctcct atccctactt cttacaggtt atcacataag gaatctgagc 60 cacttcttat tttgaaatta tttcatctgt cttaatgtca gtttagtatc tgtaacaata 120 acttatttca ttttctttcc aatgaaatat atctttatct ccataatact tagtgttcca 180 taatgatatg tggaattgaa gggctctcta caacacaatc tcctcatgcc cacacctacc 240 ttcaacattt atcttaagct aagccactaa gagctttctc aagttgtgct tcctaaagct 300 gcagttctca aaatccaccc cacataccta tgaagcccat ataggaagcc ccattttaga 360 aataattttt gtaatcgaat aaatattaga aacacttcac acctcctctt gg 412 <210> 736 <211> 390 <212> DNA <213> HUMAN <400> 736 ctccccattg ctcctagctc ctgaggctca ggacccctgg cttctgtcct ccctgctcag 60 ggtcctgcag cgttgcctct gctcagccat gctcctgctg ctcgtcccag tgctcgaggt 120 gatttttact ctgggaggaa ccagagccca gtcggtgacc cagcttgaca gccacgtctc 180 tgtctctgaa ggaaccccgg tgctgctgag gtgcaactac tcatcttctt attcaccatc 240 tctcttctgg tatgtgcaac accccaacaa aggactccag cttctcctga agtacacatc 300 agcggccacc ctggttaaag gcatcaacgg ttttgaggct gaatttaaga agagtgaacc 360 tccttccacc tgacgaaacc ctcagcccat 390 <210> 737 <211> 192 <212> DNA <213> HUMAN: GTAAGCATTCGGAGGGCTCTCTGGCTTTCCGATCTTGGGTCGCTGTACTTGGCTCTGAAT ACAGTCACCCCATCAGAGTAGCAAAACACTGTGGNTGTAGTGTGAGAATCCANTGTTAAT GTTGCCGAANCCNNTGNATTTCCTTCCNTGANAACATAGCGCGAGAGAATTGGAATGNGT TCCAAACNTGTGAC <5541621H1;DNA;HUMAN <400> 737 gaattttctt tttttgtttt ggtgaacata tatgttctta tttctgatat tatattgttc 60 ataggaatgt agtcatattt gctactaaaa aacgttcata tggtttgata ccacatttca 120 gcatttcaca atgatctgca acttccaaat gctctgcact agaacaagtc tgaaaatcac 180 tcaactggcc tt 192 <210> 738 <211> 160 <212> DNA <213> HUMAN <400> 738 acaagattct gatataatga acctaaatca aaattcacaa atggtggctg aaatcctgtg 60 agagtacaac ataaatccat agttattgtg cataaacaat tcaaaattag tttataaagg 120 gaacgtcaac aagtcctata accaccacct tattactaat 160 <210> 739 <211> 306 <212> DNA <213> HUMAN <400> 739 ccctaatttc cctaaccagt gctggcccag gtaacagaat attgggttgt gacatactat 60 gttttgtctg acttgctgga ataaaattac ttgagagcat tgaaaccaca caatcagttt 120 tcacctaata tcagcagcgc tcattttccc cgtcttcctt tggaccccag agccacagag 180 acaaccaaca acaagcagat ggcccagtgc cctgcctcag aagatttatg tattcctaag 240 gaatagccag cttaatggag attcacagag agggtttctt tctattctta ttattcagat 300 aattca 306 <210> 740 <211> 371 <212> DNA <213> HUMAN <400> 740 cttgagagga aatgcaaaag tttgaatcca ggactacttc ctaatcaatg ctcaatgcca 60 gtcgatcggt ccacccttgg caagtgtagg tgtgcctttc caggtagctc attgaaaggg 120 gcacttcttt gtagcaggcc cgtggacttg attggcatgt gtgtgacact ttgtggcact 180 catgggtttg tgctagactt tattaggttc catagtcctg taggctctga actctaaaag 240 aatgtgtgag ttacagaaaa gattccacac tggtcataaa agaaccaaat gctaaagatg 300 caaagatagt aaaataggta tatgagtcca ttatatatag gaaggtgatt ccaagaatga 360 aactaccaca t 371 <210> 741 <211> 285 <212> DNA <213> HUMAN: CAGGTGCTCAAAGGAAAATTTAAGACAGTCCATGGAGGAGAAAGGTATAGACAAGGTCAT GCAGATAT <5911413H1;DNA;HUMAN <400> 741 ttattggttt aagttctaag caattgctgc tcttactgat ggcatccgca gcctgtctgg 60 tgcagtcact gcagggatgc cagcttcaac aggggaagtg cagcccggac tgtgcactcc 120 atatagctag caggggccag gaacaggagg gagtcccacc ttctactgaa ttaaaggggc 180 aggagcccca tgcttcccaa cacaaatgca gctgcccaga tgtggctctg gacccaggca 240 tccctgtgct ctcaggaagc ccctccatgc cctcacaggc tccaa 285 <210> 742 <211> 536 <212> DNA <213> HUMAN <400> 742 ggacgggctc ctggtggctg tgctgctgct gtgagcgggc ccctgctcct ccatgccccc 60 agctctccgg ctgggtgggc ttggccatgg tcagcgtgaa cgcgcccctc ggggctccag 120 tggagagttc ttacggtaag tggggctggg ggaagactgg acagggcggg actgcggtca 180 gctttgggag gccatgggac acctccccgt gtgtttctta cgggcccaaa gctcctcctg 240 gagctcctct ggaagggcag gaagccccac ggaggcaatg tgaccgcttc cctaagctct 300 caagccgggg catggcctgc ttggtgcgag aagtgctggg aggggccgag aagccctggg 360 gcagaggctt ggctcatttt gtctgtccag aggccttcct gggaatgcat ctcaggggtc 420 tttccaaaac cccacagagg gtggggcttg gaagcaccgt cctgtttcga tgcggggcaa 480 attgaggtcc accaggagag gcttgctggg cctaggtcac gttgctggtg cattat 536 <210> 743 <211> 253 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(253) <223> N=any base <400> 743 aggngggcna ncaannnncc agggagnagn nctgnnncnt ctctcaggag aggttcctgg 60 gaagaagctt gtcgctttgg atcagtgtaa tttcttccnc cgttcagggc cactcataca 120 gtaatcggaa gtacgagtct gacgaagaca gcctgggcag ctctggacgg gtaatgcgcc 180 ctgaggcacn cttgtctctg cctcttcctg tctcctccag gctctgttgc tgtttctcct 240 gtctcatatc tct 253 <210> 744 <211> 392 <212> DNA <213> HUMAN <400> 744 agccagtggc cagcatgagc cggagggagg gaagtctgga agacccccag actgattcct 60 cagtctcact tcttccccac ttggaggccc agatcccgtc agacacacag ccttgcgcac 120 ctcctcacca aatacgctga gcagctgctc caggaatatg tgagtgggaa tgggggtggg 180 ggtgccgggg gcctggggaa tgggagcaga catcacagag gtcctcgtat cacccattct 240 ctcaacctca ttttccaact gtggaaatca ggggctcctg tagtaggtga cagcaagttg 300 cccctggtca cacagcaaat tggcaggagg accctgtctg tgacccagat gccactctgt 360 cctctccagc ttagaggcac cctcctcagt gg 392 <210> 745 <211> 562 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(562) <223> N=any base <400> 745 ctttgcaaac ataaatctgt tggtgctcag gctagctggt agagccccat caaaaattgg 60 atgcctttga aaagtttgct tagagcaggg gttctaaatt tggtgcgcac aaatctccat 120 ggataaaatn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 180 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 240 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 300 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 360 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ntgttgatat tttaataact gtcttttgat 420 atcattggtt tgccttgtaa tcttatgtat atagatttat taagttttcc ttttcttgcg 480 tgtgagttgt cccccattcc aaagtattcc atctactttt ctaatcgcgt cccctttgca 540 ggcctctctg gggatggact gg 562 <210> 746 <211> 576 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(576) <223> N=any base <400> 746 caagtatcac tgtatttccc tagaaaacct gaaatatcga tgaattttct gtggcactct 60 aggggtccct tggtgcacac tatgggaacc atgggattag gaccattagg atttgattat 120 ggcttcttcc tgcctcagat ctaatcttta cctggcattt ttgccttaaa gatgaaagaa 180 gcatacattt tgatgtattt nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 240 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 300 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 360 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 420 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 480 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnggccctt tttcatttgg ggcttattct 540 ttggagagaa acccggataa aagcctatcc tttaat 576 <210> 747 <211> 519 <212> DNA <213> HUMAN <400> 747 tgaaaacaat aacagcataa ctgagcaaat cactgatgtg gtgaagcaac cagcctttat 60 agctggtatt ggtggtgcct gctgggtaat tctgatgggt tttagcatat ggttgtattg 120 gcgaagaaag aagaggaagg gactcagtaa ttatgctgtt acgtttcaaa gaggagatgg 180 aggactaatg agcaatggaa gccgtccagg tcttctcaat gctggtgatc ccagctatcc 240 atggcttgct gattcttggc cagccacgag cttgccagta aataatagca acagtggccc 300 aaatgagatt ggaaattttg gccgtggaga tgtgctgcca ccagttccag gccaagggga 360 taaaacagca acgatgctct cagatggagc catttatagt agcattgact tcactaccaa 420 aaccagttac aacagttcca gccaaataac acaggctaac ccatatgcca cgacacagat 480 cttgcattcc aacagcatac atgaattggc tgtcgatct 519 <210> 748 <211> 347 <212> DNA <213> HUMAN <400> 748 gagagttata aaaggtttac aagaatctca cctcatgatc aaactgggta agatttgata 60 gaattatctc taaggtttca ttaaaaaagt tggggttgac attaatagta gactaacgca 120 agggtgaaat ttggctttct cctcttgcac aggattttca tgtaacatta aagacagatt 180 gtttggaagc taagtcctcc ctcttaatga gtgaaggttt ttgccttgtt ttaaaatgtt 240 ttggtcatga ctttggctaa aataaatagt ttatagtaat ccgtaattgt acttcataat 300 atcaagtgct ttgaaccgct aacatattta acaggctccc ccaaatc 347 <210> 749 <211> 797 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(797) <223> N=any base <400> 749 ggatttccgg gttgcagtga cctatggttt caccactgct actgcgcctg ggcaacaaat 60 gagaccctgt ctcaacaaaa caaagcaaaa caaaacaagg gcaactatgc catatgacat 120 catcaaatca caggagtgat aactcatcaa attcacaggt cctgttctgt gctgcctaac 180 caatacttgt tattggcagg gttttagggg tctgtatact ttttgtgtta ttatttaaga 240 aatcattttc ggccaggcgc agtggctcac gcctgtaatc ccagcacttt gggaggccga 300 ggtggacgga tcacaaggtc aggagatcga gaccatcctg gctaacacgg tgaaaccccg 360 tctctactaa aatacaaaaa ttagctgggt gtggtggcgg gcacctgtag tcccagctac 420 tcaggaggct gaggcaggag aatggcgtga acccaggagg cggacttgnn cagtgagcaa 480 gatcgcacca ctgcactcta gcgcgggnga cagagtgaga ntccgtctca aaaaaataaa 540 aagaagaaat gatttctcag ccttganggt ctaaaatatt taactttcag cctgggccaa 600 catggggaga actcatctct cccccgcccc ccccccaaaa aaaaaaggct tgggtgcggt 660 gggcccaccc tgttaatccc agacacttgg ggaaggacga ggtggggcgg atcacctgag 720 tttcaggagt ttgtagacca agcctggcca aaatgggtga gaacccgncc tctattaaaa 780 cataacaaaa tttagcc 797 <210> 750 <211> 412 <212> DNA <213> HUMAN <400> 750 tcatcgtcag agtcttttta ttaagataaa tccagtaaaa tttgtgtatt cacatataat 60 caaaactgcc cttctgaaat aaacatttgt atttatttta aaaatgggaa tacaatttca 120 tttttcccaa gctaataata aagttatatt tgggaaagat aagtttaact cttaacatta 180 catgaaaata gttcaccttc tttataaaag caacctgcag aacaagaatg ttggatgaaa 240 ctcttttttt gggatccctc actttatgaa attatcacat gtataaaaga gtaaaattaa 300 aattcaaaga tttgacatat aacttacaca acacgagatt cactcacaaa gttgaaagca 360 tatttttttc tatgtattcc actactataa tcacaagatt tatagataaa tg 412 <210> 751 <211> 381 <212> DNA <213> HUMAN <400> 751 gtcgaccggg atcaggagat tgagaccatc tctgactaac acgatctgcc cgccttggct 60 cccaaagtgc taggattaca ggcacaagct accgcgcccg gccctagcaa ggccattttt 120 acactttctg cagaaagggt acactcccca gcagatttgc catgagagta caccgaacaa 180 aggagacagg ttcatttata acctgacgca tccaccctac tgctgtgtcc agtttccact 240 ggctggaatg gaacctcaca ttttgtactt gttttgattg gcttagaact ttttaaaagg 300 cgtaaaggca gaggagaaga aaggaaggag gaagtaactt gtggaatgct gagaaaggca 360 aaaacatctt caaatgtcga c 381 <210> 752 <211> 330 <212> DNA <213> HUMAN <400> 752 gaggacaaat tattcaactg tttatcatac ataagaccgc atgactataa tacaaagggg 60 ggttcttttt tcatttaacg ttacaatata cacagcaagt ccggactaga tcttacaatc 120 tgaacacagg tatttaacct tttccatgct gtttatgttt acaatgcaca gaaaaaaaat 180 tgacctagtc agccacatgg aattgaccaa tagaatgaaa cgcggtgttc tgctgagtca 240 tcttaaacag gttatcggca gaggtagatt actgcttctt ttctaggctt cttttgatcc 300 tggacaggta aattacttat cttcattctc 330 <210> 753 <211> 896 <212> DNA <213> HUMAN <400> 753 gacgaagcaa ggaaggtgct gtgtaatcat taaggagcgg aggcttttgg agctgctaaa 60 atgccggatt acctcggtgc cgatcagcgg aagaccaaag aggatgagaa ggacgacaag 120 cccatccgag ctctggatga gggggatatt gccttgttga aaacttatgg tcagagcact 180 tactctaggc agatcaagca agttgaagat gacattcagc aacttctcaa gaaaattaat 240 gagctcactg gtattaaaga atctgacact ggcctggccc caccagcact ctgggatttg 300 gctgcagata agcagacact ccagagtgaa cagcctttac aggttgccag gtgtacaaag 360 ataatcaatg ctgattcgga ggacccaaaa tacattatca acgtaaagca gtttgccaag 420 tatgtggtgg accttagtga tcaggtggca cctactgaca ttgaagaagg gatgagagtg 480 ggcgtggata gaaataaata tcaaattcac attccattgc ctgctaagat tgacccaaca 540 gttaccatga tgcaggtgga agagaaaact gatgtcacat acagtgatgt tggtggctgt 600 aaggaacaga ttgagtaact gcgagaagta gttgaaaccc cattactcat ccagagaggt 660 tttgtgaact tggcattgga gctcccaagg gcgtgctgct ctttggtaca gccggtacag 720 gcaggaaact ctgtggcgcg ggcggttgct aatcggacga tggctgcttc attcgaagta 780 tgggattctg agcttgtacc gaaatacgtc cggtgagggg ggccgaattg gttctgaatc 840 ctcttgaatg gccaaaacaa aaaaggcccg cctaatttcc ttggtcgaaa ttgtgc 896 <210> 754 <211> 404 <212> DNA <213> HUMAN <400> 754 tttttttttt tttttttttt ttttgttgta gggatcctaa tgtcttttat catataaata 60 ttacacaaag aaaacttaca ttaggtatca aaaaacttta caatctgtac atttgttttt 120 ttcttgcatt tctatattat acattttgag acagaaattc acaacggtca gtaaaaaggt 180 aagtcagcaa agaaaatgag aagtgaccct gctgttaata caacaagatt tgtccttgtt 240 ttggcagata aatacctggc caaactaaag tcgtgtgaga tgcagaaatt tacactaggc 300 ttgataagcc aaagcctttt tttttttttt ccagatttct gtgatcccac tagccccatg 360 ttgctcaaca caaatactat taacttgtat actatacctc tttg 404 <210> 755 <211> 464 <212> DNA <213> HUMAN <400> 755 tttgtgaatt gagaggtctg ctactttatt ttgataatgc agggatatta tttatctttg 60 cagaatcagg tgactcccaa cgttcccgga atcttctagt ggtctgtgtc aggggtctgg 120 gctggctggg gttcagtgat gtctactgga ggcagcttcc atgccttctg gggtcctgag 180 tctccatggc ttgtggggtc tgggtccccc ctggattagt ggatggccag agtggcatag 240 acactgggct cagctggaga ggccccttcc tgggatggag gaggctcagt tgccttctgt 300 ctgagggtaa agctgtgcag ccgggcgtag gtcacatcct ggggggcttc agatgcagca 360 gcctcagtgt ccatctgtct gtcctcttct gcctgtctgt cctttgtgtc caggaattcc 420 ccagacagtg gggagggagg agaggccatt tctctcctag gtct 464 <210> 756 <211> 487 <212> DNA <213> HUMAN <400> 756 ttttttttta tattattgta aatgaaactg ttttctggat ttctttttca gatacttcac 60 tattactata tagaaatgca gttgattatt tttaccttgc aagtttactg aatttatcag 120 ttctaatagg ttttttttgg tagcatcttt aggattttct atatataaga tcatgtcgtc 180 tgcaaacagg gaaatttgac tttctccttt ttaatttgga tgccttttat ttctttctct 240 tgtctaattg ctctggctag gactatgttg tccttcaaca ttacgttaca tagaagtggt 300 aaaaagtggg catccctgtc tttttcctga tcttagaggg aaagctttca gcttttcccc 360 attcagtatg acgttagctg tggatttgtc atatatggcc tttttttgtg ctgaggtata 420 ttccttttat atataattca ttgagagttt ttatcatgaa ggaatgttga gttttgtcaa 480 atgaatt 487 <210> 757 <211> 467 <212> DNA <213> HUMAN <400> 757 agatggagtc ttgctctgtt gcccaggctg gagctcagtg gcacaatctt agctcacttc 60 aatcttcatc ttttgggttc aagtgattct cttgcctcag tctcccgagt agatgggatt 120 acagttgtgc gccgccatgc ttggctaatt ttggtatttg taatagagac agggtttcgc 180 catgttggcc aggctgatct tgaactctcg acctcaggtg atccaccacc tcggcttctc 240 aaagtgctgg gattacaggc gtgagcatga tgcctggctg gaaagtcact tcttatcttt 300 gagcctaaag acaaattttc ttgtgtgtaa aaccggatca taatatctgc atcctgggtg 360 gctagtggga ataaaatgag atcaggcaag gatctgcttc cgggcaggtg ctcaggaaat 420 gacagctgtt atgattaatg agcatagcag aggacagagg gtcacgt 467 <210> 758 <211> 513 <212> DNA <213> HUMAN <400> 758 taacaaaaac aactctgtat tctcgtcccc accattacca tctctccttt gtgatgtcaa 60 agagaccaga ggaagtggac agactcgggg aagaataggt aagtattaga gacagaaaaa 120 gtatgaagtc ccttctgtga ggactaacaa tagtgatgcc attttacaac cttgatgact 180 gtgttctcaa gaaacaaagc aaatgtcaac cccgtccata gcttcaacag agcataacag 240 ctctaaccgc aacagagcct aacggcccta accacatctg tccccagttg gaaagtgtcc 300 aaacagttcc aactagccag cacttcccca acccctcccc aacagaaact ttattataaa 360 agcctcagct tgtaagcgat caggatctca gccagattcc taactggaac tcttcgcagg 420 cttttcctgt aaataaacct gtttggccgt ggaattgcct cctgttactc gctctctacg 480 tttatatctt cctaacacct tccggctcta atg 513 <210> 759 <211> 378 <212> DNA <213> HUMAN <400> 759 ttttttttgg tattttcagt tagattcttt cttcttagag gtacagagaa agggaggaaa 60 atagctacag acatggtgta agtaggtcac agcagtttca atgcaccaaa aaatgtgaca 120 tctccatcca gtgatatttg tgcattttct cttggtattg caagttggag ttcatctcct 180 tcttccagtt ttgcaatgcc agctgaatag caggaattat tgggtagtgt ttcaggcata 240 ttttgaatac atcgaaacaa agtcaccaga ctcaattcat ccccaaagac atggaccttc 300 ttcctctgaa ttagatgtcc catggcgtag gtcttatcag tatataaaac ctgaccatat 360 ataaaaaagt aaccagtt 378 <210> 760 <211> 349 <212> DNA <213> HUMAN <400> 760 aacattatta atcattagct tttaatatta ctctttgttg cattactaat ataacctagg 60 aataaccagt gggtataggg tcaggtgctg aagggacatt gtgagaagtg acctagaagg 120 caagaggtga gccttctgtc acgcctgcat aagggccgct tgagggctcc ttggtcaagc 180 ggtaacccag tgtctgggaa ggcaccggtt acttagcaga ctgcgagagg gagtctcctt 240 tccttggagg agtcagggaa aactctgctc cagcagcttc ttgtgggagg ctggatattt 300 atcaggcctg cgcgcagtca atccggaggc ctaaaacccc ttccctgtg 349 <210> 761 <211> 437 <212> DNA <213> HUMAN <400> 761 ggtgggtgag cagcatgggc tttgaggagc tgctggagca ggtgggcggc tttgggccct 60 tccaactgcg gaatgtggca ctgctggccc tgccccgagt gctgctacca ctgcacttcc 120 tcctgcccat cttcctggct gccgtgcctg cccaccgatg tgccctgccg ggtgcccctg 180 ccaacttcag ccatcaggat gtgtggctgg aggcccatct tccccgggag cctgatggca 240 cgctcagctc ctgcctccgc tttgcctatc cccaggctct ccccaacacc acgttggggg 300 aagaaaggca gagccgtggg gagctggagg atgaacctgc cacagtgccc tgctctcagg 360 gctgggagta cgaccactca gaattctcct ctaccattgc aactgagtcc caggtcggta 420 tttacataat ccatctg 437 <210> 762 <211> 507 <212> DNA <213> HUMAN <400> 762 ttatttggga caagaaacta aatgcctttt cagtggttca tttgaatcta ccatacttca 60 aaaattataa atctaccatc accaaagaag tacagcgcca tttgtattag ttgcaaaatt 120 aggctattta cttttctgta tgtacttttg tgaggtttaa aacgttaggc ttattacttc 180 tccttggtat gagagaaaaa gcacaggcac tggaaagaaa aaggaatagg tgtgaaatct 240 tgattttgtg aattaggatg aatgtgacct tatgtaaatt acaaagttcc tgaatctgtt 300 tgcgcagatg aaaatggaaa tatactaact gcacctacca aacacggctg actgaggatt 360 aaataaaaca atacatgtaa aggtagtgcc tggtgcacag tagaaactcc aggccgggcg 420 cgatggctca cggctgtgtg ttatcttcta cgccagtttt tctgattctc agtttataga 480 tgggaaagga gacgcttcca gcagcag 507 <210> 763 <211> 681 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(681) <223> N=any base <400> 763 ttttttttct gagtgacaat ccactttaat aatccagctt cagctcagct gagaacttcc 60 cctctcaggt gcaaagggat ggcagagaag tctttccaag agggctcaat ccactaagag 120 attatggctt agagaaggga acagctcaaa gaagcccttg aagagggtga gggtctggag 180 gactcctgtg gtgcaggcca tctcccggat agagtgcatg gccagttggg ggctgcctaa 240 atccagcacc cgcagcccca gccgagaagc caagataggt ccaatggtgg ttccacaggg 300 ggtgtcattc cggaccatga gatcctgcag ggggaccttg actttgttgg ccacctctcg 360 gatcagggcc tctgacaccg cgtttgaagc atagcgttgc ttgctgttca ccttgatcac 420 ggngcccttg tggaataaag gccggtggtt ctcctcatgc ttgtccaggt agttgggatg 480 cacagcatgg gccatgtctg cgctgatcat gaaggacttg ngtatggctt cctcgaaggc 540 tgtcgggtgc tggcacgagg ctgagatccg ccgcagcacc agctctgtca gcagtgactg 600 tgctccctgt gcactctcag accccacctc ttcgttgtca tagagtgtga ccatgcgcac 660 gtgaggctct gtggccaggg a 681 <210> 764 <211> 599 <212> DNA <213> HUMAN <400> 764 gcttgtaatt gctctattta ttaatacata tatcacaaat gttcacaata tcaatgcatt 60 cttgttggca tgctagacag aggcattact tttgaagatc ttttaaaaat attttgactt 120 gttccccctt cacactcatt tttaaattgt ttggatgagg tcctcaatgt ctataatgtc 180 aatgcaagaa aaaatacaga gagaagtagt aaaataacac aatagcaatt aattggggaa 240 aaacaaaata tcatggcctt cacaagaagc aacaacacag ctttgtaaca gggttataca 300 ggtttcaacc gagaggcaaa gatgcactaa actgcctaca catacccagg tatgtaacaa 360 gcaaggaggc cacctcaagt tcagttttcc ttcttgcatg acacatgctt tttttctcct 420 catggacaat tattgaagtg tttcgttaca tgtcttaggc agcctgaaga aggtaggaaa 480 gccttagtag agggaaaatc aaaccaaatg agattaagtc aaaagaacag ataactatcg 540 tctgcttatc tacttaaagg tgtgtggcat ttaccacagt gaggagctaa caggagcct 599 <210> 765 <211> 330 <212> DNA <213> HUMAN <400> 765 gcggccgccc ctgcatgggg aaaggggcca caggaaggcc ctgcgagtgc agctggggcc 60 aacaggaaca gcaggacacc ctccagaggt ggccccagcc tcctctgccc agcccttcct 120 gaactctcca tcatccctgt ctccagtcac tcagtcagca tggctgtgat ggacactgga 180 ccacagggct gaaaagatcc agagaacaca cagaggaata ggccacctta cacaccgatg 240 gggcccctcc tctgggaagg gagcactttg tgcacagaag tttgaggggg aggagctgcg 300 tgtggtggct catgcctgta aacccagcac 330 <210> 766 <211> 496 <212> DNA <213> HUMAN <400> 766 tttttcacct tttatcacaa agtttttatt gaacaaaaat aatatgacag taaaaatgat 60 acataaagtg aagatttgca gtcatagaaa agatgtgtac aaagagacca acattcaggt 120 tatatagttc tataaaactt ttcccatagc agtttaacac tgattaagca gacataaaag 180 ggaaaagaaa gtcattaatg ttctttgaaa cctattttct gagtaaaata cctctgctaa 240 cacacacatg cacacacaca cagaatgagg cagagctata tgactcaggg atgaggtcag 300 gacccgtgtg gctcagaaaa ttctgcgtta gctgccgccc acatgccttc cgcttgtcat 360 ccggggtcac ttcatactcg gccaccccat ccaggaaggc gacgcagcgg ctcagctccg 420 gcctcgtggc acagaactct cggaacagca ggcgcccaat gggctgccgc tcgcacaggc 480 tgtgatagtc acgctc 496 <210> 767 <211> 456 <212> DNA <213> HUMAN <400> 767 ttaagatttc acaaaaaaag tgataaattt tctggggcct acagaagggt aaaggtagaa 60 gtaacacaag atgaatcaag gataaaagga ctccagtggt ccaggaagtc accgcgaggg 120 tgatgcagac tctccaggtc atgatggcca aatatcggag ggggtggcag atggccacgt 180 acagatcata ggacatcacc accaggagga gacattctgt gacagcaaaa gtggaaaaca 240 gaaaggtctg catcatgcgg cccgcaaagg agatgggctt ggctggatgc aggaggttca 300 ccagcatccg gggcaccgtg ttgcaggcgt aggcgatgtc gacgaccgcc aggtgtgaga 360 ggaagaagta catgggggcg tgcagtctgg agtccagtga gatgagcccc agtatggtcc 420 cgttccccag cagggtgaag acgtagaaca gggaga 456 <210> 768 <211> 616 <212> DNA <213> HUMAN <400> 768 tttcttttct tttcttttcg gtctctccct ttctttatgg gcttttccta aacactttct 60 tcttttctta tgacctggat ctcagtttca ctatgcactt ccctaaccta tttctcctaa 120 tttcagttaa ggtaaaaagt ccacaggtat cagaactgga acctgaagtt aggttaaaat 180 gcggtgacaa aagaagcaga cttcattatg ttcttaagag ttcaggctct taagatttat 240 tacccctttc ttttgtcctc tcctggagaa tagaatgagc caagatcagt ccttacttga 300 gcaaatcact ccagcatcct cagcatgatc acagttatgc tttccccatc cttgatgttt 360 gcagttccag agagctgact cattttcggt ggcatataaa atcatcaacc cagattggtc 420 cagagccttc tccaaaatta gatgaaccag agaaactgac agcacttcca cattcaagtt 480 gtctacaaat gacagatgca tgatctatgt tgaagttatc atcacacact gttccccacc 540 gtccttggaa tttgatctct attcttccag aacacatatt ccctccacgc gtcagcctca 600 tttccaaatt ggatcc 616 <210> 769 <211> 455 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(455) <223> N=any base <400> 769 atcagcaata acaaagtctt gaggaatttt gtccttttat ccatataatt ttagccttca 60 tcgtttggca tacaggtagt gacctgcata tcctggcagt ttttgaaatg atagtgactg 120 ttctaggcct ccgctgatgg catagtcaaa caccagattt ccttggagat gattcggaaa 180 tgcctgctgg aagattaatg aagactccat tctgtgtttc ataacagtag cgttgttttc 240 tccatcaaaa acagagggtc acagaaatgt gctgaaaaga tgtggtccag caaggttctg 300 tagtcccacc tcagtgcctg tgggctgtgt ttttcactgt aacaagcact ttggtaaatc 360 actccatggc tntcctcatc ctcctctctt ttttcttctt ggtgggaagc tggatngcgg 420 gcatgcatca atctgtaatc tcagctactc gggag 455 <210> 770 <211> 517 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(517) <223> N=any base <400> 770 gagaggattt ctttatttcg cgttcagacc caacacactc ggacaccttg gggccctgtg 60 agggctaagc agggtggtgg cgtcagctcc cggggaggcc ccactccctg gggaggaaat 120 acacggcagg aggccgcacc cagccccccc acggagggac ccgtgttgct ctaacaggga 180 cactgaagtt gcctctgccg ccccgtgagg ggcctgtggc ggccccagac ccagcccagc 240 caggccagag gagcctccca ggggccctca ggtggtgagg tgggggcttc ccggccccgg 300 tgcccaccgg cccttctagc tgcctgtgct gggccaggtg tcctctgagg ccggcaggag 360 tctggccccc gctgcacctg cgcttggtgg ctggcagggg cggngtaggg aggtcaccct 420 cgaggccggg gtccccatgt gctaggggaa gacctgcctt cccagccagt gtccacaggg 480 cagcaattcc acgctctgag gctcagggac caaggca 517 <210> 771 <211> 451 <212> DNA <213> HUMAN <400> 771 ctggaagtaa tgtctgttta ttgatagaaa acaggccacg tccagagagg cccagggcca 60 aaacctcctt ctggaaggcc gaagtcccac agtgccgggg agcgcaggag tcagctcggc 120 tccgtcttgc cagggctggg gggaccctca tcctcacccg cttccggagc tgcagtggat 180 gtgggggccc ctgcagcctc cagaaccagt tccagggccc cctcgcccgc cacacggtgc 240 acctgctcgc ctctggccgt caggatctct tcgatatttc tcttcccatt caggtccgag 300 aaccagccca ggttgtcagc gatgatatgg tggttctggc agccggggca ggtcacaatg 360 accacgcctt ggtgataggc cagcttggag atgcgcttgg aggacctagt cccgcagacc 420 ttgcaggtgt agacgagctg gtagtgcgcc g 451 <210> 772 <211> 460 <212> DNA <213> HUMAN <400> 772 tttgagatgg ggtctcgctc tgtagcccag gcgcgacctc ggctcactgc aagctctgcc 60 tcccgggctc atgccattct cctgcatcag cctcccgagt agctgggatt acaggcgccc 120 gccaccacgc ctggctaatt ttttgtattt ttagtagaga tgggttttca ccgtgttagc 180 caggatggtc tcaatctcct gacctcatga tccacccacc tcggcctctc aaagtgctag 240 gattaaaggc gtgagccact gcgcccagcc acaaaagatc tgcttttaac aaaaatttgt 300 aatgggttat aaaaagttta tgtgaatctt accttatggt caagcattaa aattgggtag 360 atatgtctat aaggctttct taagaattgg gtgtcacata aatagtacac taattccaag 420 gtaaaatttg gcttatatgg tataaaagtc atacaggaag 460 <210> 773 <211> 393 <212> DNA <213> HUMAN <400> 773 tcgcgtttct cattgtcttg agattctggg aggaagcctc tggggcttca cagaggggct 60 ccctaggggt aagtgcagga ccctttgcag agctaccagg aaagagggct gatcacacct 120 caggcagccg ggttacaatc cgcataaaaa tctgagtctg gggagcgtgc gacagaggca 180 ggcagattgt ttaaggcgtt cgataaagtc ggttgatgac agacacagat gtgtgttccc 240 agccgcattt gtgctctggt gtgtgacagg tctgtccttg cctgctttca gctcccaggg 300 cccctttgag tctgggcagc ccagtcagtc cccgtccatt tttggcctta gcttttcctt 360 ccctggctac atctgggccc agaacaagtc tcc 393 <210> 774 <211> 450 <212> DNA <213> HUMAN <400> 774 aattttagaa acaaatatat atttttgata gaaactgtaa gtaaatattc agtactacca 60 gaaatatact atcttcaact ctcggctttt ttccaaaaga tacagaatca ttttttggaa 120 aagatacaag atgtacagac aaatcacatt cataccttac aatttaaatt cataatgaac 180 aatgaatatt ttcatatttt ccagaagttt gaaatttcaa agttgttagc aaaattattc 240 atttccataa tttttacgag taaaaataga aagagctgat catgtacctt aatattgtca 300 ctttatatat tactcaaaag tacaaataac cctaaaagta gaatcccagg cttatcatat 360 tataaaaata ctgagacatt tatcaaacat aactaatata aatgaaacta catttttaaa 420 aatgtttcac aaacaccagt ccatctttct 450 <210> 775 <211> 543 <212> DNA <213> HUMAN <400> 775 ttacattttc tcagcaaggc aattttactt ctatacaaga gtgcgtctca tggatggtgc 60 aatggcgaga gcacaccgga acaagggagg ggaatgggtt cttatccctg atgcaggtac 120 cccctactgc tgtgttgttc ccctatgggc tagggttgga ccgcacaatc taagctaatt 180 ctgactggct attttaaaga gagcaggggt ataagccaga gtggtggggt gagaagttta 240 gacaggaaag atggttacgg accaggtgac taaaggtgac tcaggtcaga gcaggtgaca 300 gaggctagga ggggattgtt tactgaaact aggggcaagg agacataaag aatgaggaaa 360 ttaaaagtta aaatgaagaa caaagaacag gtgagctgaa catactgata cattggttct 420 ttggagagga tctcagaact caatgtactt aacaaattac aggctaaaac ctttgaagaa 480 gaatttatga tatcctacat tatcatgggg taaacaattc gtccctgaca gaataaggct 540 act 543 <210> 776 <211> 472 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(472) <223> N=any base <400> 776 cggtggtgac gctcagggtg accgcagtga agaggtaaat gactcggagc tgtcccccca 60 gggccctccc gaagcccgtt ttatcccagt ggattccgcc gaccacgtat ccaaagcctc 120 ctccgagacc tgccaggagg gcgtggatgt tcaggcctcg gtcctggtct gcggggctgc 180 acacgtccat catgtaggcg tggctggggt tgtccgccga gtcggcgcta aagtccatca 240 gcaccacacc gcacacggtc agcagcaggc cccacttgtg gttcccggtc acgtcagcca 300 gggcgatgcc aatgtcccgg ccattcagca agagcgagag gcccagcagt gcccctatag 360 ccaggacaag aatgaaaggg cgtctccttc caaaccttga ggtacaccgg tcactccaag 420 cacccaacag aggctgcagt aggaatccga ggatngggct gatgaaccac ac 472 <210> 777 <211> 592 <212> DNA <213> HUMAN <400> 777 cttcttttac tggcttccgg ccgtctccca actcgaaccg ctcccgcggc ggccgaggcg 60 ggctgcgact ccagtggctg gctttcactt tgtcgctgta gtcctctctc atcgttcggt 120 gatgtgcaga cacttccctg cgggcctccc gctccttgcg ccgctcctcc gcccgccgct 180 cgcgctcctt ctgctcccgc tgctccttct gctgctcccg catcttgcgc tcccgctccc 240 gcttcctttc taactgctcc aagcggtccc tttctctcct ggaatgctcc cttgccatct 300 cccttctctt ctgtctttcc cattcccggc gagctttatc ctgttcttct cgatgccgtt 360 tccgacgttc gtgctctctt tctttttctt tcactctagc atgcttcccc ccttctgctg 420 aatggctacg atgcctacgt ttctcttttc tcttttcatc ttttctgtga tgagcttttt 480 ctttccgaga catttgcctg gggtgtttga tggccaaaga atcatcttct tctcctctgt 540 cttccataga gtcttctctt ctatacgggg agttccttat tggatctccc at 592 <210> 778 <211> 649 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(649) <223> N=any base <400> 778 acttgattat aggcagcctt gataacatct ccagcagctg tggcctggga gatagtataa 60 atcccaaaga gtccagaatc tgagtaactg gcattaaatg cagaaacatc aaatggctgc 120 tgagttgcct tggcaacagc ctggtgcaga tggctggtgg tgttgctgcc cctcttgaca 180 tgtggcccag caccgaggac atgctgaaga acactaaatt catttgcctc tgcacttccc 240 gcgacagcac tttctgctac aaaagcagca tggacaagac tgtctccatt ctgttctcgg 300 atttcacctc cacggtagtt ggcctttgca ccagataaac caagcccacc cctcatgttg 360 agaaactgtt cagcaacttg ctttagaaca ggatgactca caccaagtcc aatcaaagcc 420 attcttgcac ttgtgaaatg gttctgaacg aagtaatgta actcctctga tgtcactttt 480 ccaatcctat agtcaggaca atacaaggga ttagccaagg cattccggta agctgctgca 540 tgcaaatttt caatgacatg agtctgcgga ttctgaaagg ccacagctnt gtcaatcttt 600 agctgaggct gaagtcagct acttcccacg acgaaattct ggtgctgtg 649 <210> 779 <211> 348 <212> DNA <213> HUMAN <400> 779 tttttttttt tttttttttt ttggagaagg aagggcttta ttcagctggg agcatcagca 60 ggctactgcc ttaaaatccg agctccccga atgcacaatt tccgtccctt ttaagggctc 120 acaatactaa agatttcaca tgaaagggtc atgattgatt tgagcaagca ggcggtatgt 180 gacaggggct gcatgcaccg gtggtcagag agaaacagaa cagggcaggg agtttcacaa 240 tgttcttcta tacaatgtct ggaatctatg aataacatca gtttctaagt tatgagttga 300 tttttaacta ctgggtttag gccaggcagg cccaggccgg acgcgtgg 348 <210> 780 <211> 575 <212> DNA <213> HUMAN <400> 780 acattttgaa aatttaatgg caattacaca caaattttaa tttaaaataa tattaaggac 60 ttaatctgat ttacagaaat gaaatgcaat gaagagatta agggctaacc tccattacta 120 taaaattctc tggctaccat ctagcacagg agcaactgga ttgctttcag cagtcttgaa 180 gcactaaaat atcttaaaat tcatatggag aaatagtatg tatctctaca ttaaatttag 240 atttgatatt tattctctga cagatcagac ccagaatatt aatttttatg taattgaacc 300 aaaaacattt agcaatcctt catttagtaa tcttttgtat aaatataaaa atctctgata 360 agtgaaatgt tttttcaaat tatacttcta tttttcacag ctttataggt aattataatt 420 ttcaaacttt aaatatttca tgtgatttga tatatctgta cagaaagagt tagataaaaa 480 catttaataa gattaaatct aatttgcaaa aattggtatc tgacatttgt tgtgtgctct 540 tgcaaagagt gcataggaca tttctgcagc aatca 575 <210> 781 <211> 499 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(499) <223> N=any base <400> 781 gacaaagaaa tttattaccc ctgaggcaca aaacaattaa acataattat aattattcct 60 aataatgtat actatgttac attagaatta taggagtttc acataatttt ggaacatgta 120 ctgataacac tttaatcaaa agcagattaa tactttaata aaactatgtt gtgctttaat 180 tccagtgttt atgaataaac tgaataaaag tcctttaatt ttgggtaatt ttcacacata 240 gaatttcttt tataggatta atttttcaca aaccttccac aacttgctca aaccttcagc 300 tttatcctat ctaacataaa acaatccttt aaccctccaa actaggcaaa acttacattc 360 ccataccttc ttacaatctt ttaacaaaag cacattctac tttncctgcg taccttacat 420 gtaagactgc ttttccagta gtctcaagaa catgttacat ggctaactgt tcacaacttt 480 tacttttgcg aaaaacctg 499 <210> 782 <211> 550 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(550) <223> N=any base <400> 782 tttttaaaat taaactgtat tgtttcctgg aatgtaaatt tagctttgct taatagtaaa 60 ataagtgagc catcttgaac actttaagtt tatactatat aatttcttaa tgaacattgg 120 caaatagagt agctaagaga ttgacaagca cattacgttt agataagcat gtgatgcaga 180 agttgattca agcaagtgaa tccctgacat tttgaggatc tcacattaga caccaacaaa 240 ttaaagctcc aaaattattt attttttatg tgttcctcac tttagaaacg tctactgcat 300 attactggat atttgtatac taatacactt acctatttta cattgtgttt taaatttagt 360 taaaacttaa ccgtagaagt ctgttcaaac gcgaaaggtc ttgctttgtt tgttttaaat 420 acatttattt tattagaaag gatgatattt cattgnggaa tagtttcttt catttggggg 480 ctatgtgttt caataacatt cacttggaat cagctganag ctgtaatatg tctttgaaat 540 gagccatgat 550 <210> 783 <211> 385 <212> DNA <213> HUMAN <400> 783 caaactgtaa gtccggtctc tatatatctt tacttcaacc tgattggtcc tgggccaagg 60 ttccgggcca agctaagtca cactttctcc aaaatagccc acaaactaag cacattcctt 120 ccccttccca gtccataaaa accccaaacc cctgcctcat agggggaatt ccatttgggt 180 ccccctctct gctggcaaaa agctttcttc ttttgcttat taaaccttca ctctaacctc 240 acatttctgt ctgcactcat taatcttctt aaaaataaaa caaaaaactc caggtgttat 300 ctcaaacaac agaaaaactg ttacatcttg gtgcattact aaaattacat ttctaaccaa 360 tgtctttttt ttttgagaca gtctc 385 <210> 784 <211> 455 <212> DNA <213> HUMAN <400> 784 atacggagtc tggctttgcc acccaggctg gagtgcagtg gcacgatctc tgctgacggc 60 aagctccgcc tcctgggttc aggcccttct cctgcctcag cctcccgagt agctgggaca 120 ggcgcccact agcacgcccg gctaattttt tgtattttta gtatagacgg ggtttcaccg 180 tgttagccag gatggtcttg atctcctgac ctcgtgatcc gcccgcctta gcctcccaaa 240 gtgctgggat tacaggtgtg agccaccgca cctggccaaa gttatttaat actatacaaa 300 ttgctgttta aattttcgga tatctcttta aacttttatt tttcaagttt tcttggtgaa 360 attagagaat atggtctcta aaattttggc attatggaca aagcgaccat ttaagaactt 420 tcacttttct ttattggctt tctgcatttc cagag 455 <210> 785 <211> 725 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(725) <223> N=any base <400> 785 ttactggtga atcttttatt tggacaagac aaaaacatct ccacactgtt cccttttata 60 cagaaaatgg aacatctcaa atatattagt ttttctcttt ttcaacagaa ttcatttcaa 120 tctggtccca ggaactgctt ctcattttag gattcacgtt ttagtaacac atatgcaccc 180 attacagcca aaagagcata cttgaatttt ggatagtcat tcattattat ggtgaccata 240 ccaacatatg gtaaaaaccc tcttgctctt cccaccacgt ccttcttttc cagccagttc 300 tggccttctt tgtacaagcc tctatcatca acttcattat tatctccttt agtcagaaat 360 ttgatgtctc cattatcttt ttcatgaact ttgattactc tgtgaactat tggaatgtct 420 cgtccttcaa ctttaaaaac aactatttca ccagctctga ttgggtcttc ccggaaattt 480 gtgaggaaca ggaggtctcc tctgtgaaag gccggctcca tactgccact cagcaccacc 540 acgatggggc tctcactgcc tgtgagcacg atcaagcctt tccatatcat gagtgcagaa 600 gacacgatca tggcgaagtt taaaacctgg taatagagct ggcgcttgtt catcttcttc 660 angtccnctg aagatatccc agtccccgac gcggngagat gagcctccac ggcgcccgca 720 cgcac 725 <210> 786 <211> 547 <212> DNA <213> HUMAN <400> 786 ttttgattga tttaacataa atactatggt ttatttctag atggcaagga aaatcacgtg 60 taagaggttt ccatttaaaa gaattccact attcatcaaa attttcatct attctcaaga 120 ctgttgattt caaactaggt ttagagtagc aaagcatatg aattttacag tagaagacat 180 gagaaggata taaaagtttg ttttctgtat tctttcaaaa ttcttatttt gaaggccttc 240 tgggcatata agctattgga acttgtcatc acttaaacta tttcctataa agatgaaaat 300 caggctaata aaaagtattt ttagaaatta ggctgaaaac ctctaagttt ggtaaaagac 360 ataaaactgc aaatttatga attggagcaa attccaaagg gaataaaaca aggaaactca 420 tccccaacat aatgaaatgg ctaaaaacta aagataaaga aaaatacctt gaaatctgac 480 agaaaaatga cacactacat acagggaaac aacaatttga atgactgcag atttctcatc 540 aggaaat 547 <210> 787 <211> 490 <212> DNA <213> HUMAN <400> 787 tttttttgaa tagtttaata gttattattt aagtaaggct ttggcgtgct tttccacatt 60 tttaggtttt tttctctatg tgtacacctt gcaagatgta tcattaactc atgaaaccac 120 cagctcctca ggcaacgaaa agggaggtag aaagaacgcc agaaaggtgg gtctgtgtgt 180 tctggggtgc gtggggcccg cccccgagga aggtgccaac cgtccctgga gagcagaatc 240 accaggcctg ggaaagccat gcgggttcga gagcctgcgc catggccatg ctgggcaggg 300 cccaaggggt gcccaggcgt ctgcccactg agaacactgt tagtgcggag ggatccacag 360 gaggggagag cggcgccagg gtcccggaca caggcaaggg tctctagccc gccacccacc 420 cactgccctg ggggtctctg tcaggcttct aggagacaca gagactctga ggtcatgtct 480 cgagggtggc 490 <210> 788 <211> 812 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(812) <223> N=any base <400> 788 aaaattttaa atctttaatt tccgttttca cgtattttct tcttgcttcc aaaaggaaag 60 gagtgcgtag ctctgttgcc tgtacatcgt ccacagcccc tgggtcgggg cggggtcccc 120 tgggccgccc ggggggtcca catgcagccc ctgggtgggg gccggcgcgg ggtgaggtcc 180 gggggccgcc ttattgctga ggtccggccg gttggggccg ccgctaggcg cgctggctgg 240 gcagctcctg ggagatgaag cgacgcaggc gctccaggta ctggctgtag agctcgatgt 300 cgttgtgccc ggcgccctcc acccacagcg gctccaccgc cttggggcag cgctcgtaga 360 gcgccagccc gtgcgagaag tcgatcacct cgtcctccgt gccgtggatg atgagcacgg 420 gagacgtgat cttggacacc ttctcgatgt tagggaaggc gtcgaagcag taggtcttct 480 tggtgtcggg gaaggcgacg cgcatgcccg aggtgagcgg cgagtgcagc accaccgcgg 540 cacactcgta gcgcgaggcc aggtccacgg tgggcaccgt gccgatgctc tgcccgtaca 600 ggatggatgc tgtccggctg atgccgtacc ctgtgcgcan ggcctgccaa ngcggcgtca 660 tgtcngccat agagttccct ctcgaaggcc tgcccgagct ggcaccgtaa gccggagtag 720 tcgtaggaag agangtgcag tggaggcggg agcccangcc aatgtagaag ctgctcatcc 780 tgggcangtt ccacggccat gccgtgcgag aa 812 <210> 789 <211> 668 <212> DNA <213> HUMAN <400> 789 acggatattg tttcacgatg atagaagagg atgactctgg gttgcctgtg gtcacttctg 60 gttgcctagg actagaaggc tcagattttc agtgtcggga cactcccatt cctcatcaaa 120 gaagatcaat tgaatgctgc acagaaagga acgaatgtaa taaagaccta caccctacac 180 tgcctccatt gaaaaacaga gattctgttg atggacctat acaccacagg gctttactta 240 tatctgtgac tgtctgtagt ttgctcttgg tccttatcat attattttgt tacttccggt 300 ataaaagaca agaaaccaga cctcgataca gcattgggtt agaacaggat gaaacttaca 360 ttcctcctgg agaatccctg agagacttaa ttgagcagtc tcagagctca ggaagtggat 420 caggcctccc tctgctggtc caaaggacta tagctaagca gattcagatg gtgaaacaga 480 ttgcaaaagg tcgctatggt gaagtttgga tgggaaagtg gcgtggcgaa caggtagctg 540 tgaaagtgtt cttcaccaca gaggaagcca gctggttcag agagacagac atatatcaga 600 cagtgtcgat gaggcatgaa gacattctgc gttcattgct gcagatatca aaggtacagg 660 gttcctgg 668 <210> 790 <211> 514 <212> DNA <213> HUMAN <400> 790 gcacgagtct gatggtgtgt tttgctggtt ttaacttaaa agaaaagata tttatttctt 60 ttgcatggct tccaaaggcc acagttcagg ctgcaatagg atctgtggct ttggacacag 120 caaggtcaca tggagagaaa caattagaag actatggaat ggatgtgttg acagtggcat 180 ttttgtccat cctcatcaca gccccaattg gaagtctgct tattggttta ctgggcccca 240 ggcttctgca gaaagttgaa catcaaaata aagatgaaga agttcaagga gagacttctg 300 tgcaagttta gaggaagcgc ggattctatt actggaaact ttgggactga aaggccaaag 360 cttctgggcc caccatcaac gcagctccgc tttcatttct ttcacataca actttccaca 420 taagatttca tgcggaaaaa aaaaaaaaaa ctcacaaagg ttttatactg aaaaaaaaaa 480 aaaaaaaaaa aactcgaggg ggggcccggt ccca 514 <210> 791 <211> 582 <212> DNA <213> HUMAN <400> 791 gcgtcgaccc accccaaatg ggtcctcact gccgcacact gtctaaagga ggggctcaaa 60 gtttacctag gcaagcacgc cctagggcgt gtggaagctg gtgagcaggt gagggaagtt 120 gtccactcta tcccccaccc tgaataccgg agaagcccca cccacctgaa ccacgaccat 180 gacatcatgc ttctggagct gcagtccccg gtccagctca caggctacat ccaaaccctg 240 cccctttccc acaacaaccg cctaacccct ggcaccacct gtcgggtgtc tggctggggc 300 accaccacca gcccccaggt gaattacccc aaaactctac aatgtgccaa catccaactt 360 cgctcagatg aggagtgtcg tcaagtctac ccaggaaaga tcactgacaa catgttgtgt 420 gccggcacaa aagaaggtgg caaagactcc tgtgagggtg actctggggg ccctctggtc 480 tgtaacagaa cactgtatgg catcgtctcc tggggagact tcccatgtgg gcaacctgac 540 cggcctggtg tctacacccg tgtctcaaga tacgtcctgt gg 582 <210> 792 <211> 422 <212> DNA <213> HUMAN <400> 792 tttttttttt tttgagacaa agtcttgctc tgtctcccag gctggagtgc agtggtgcaa 60 tcttggctca ctgtaacctt tgcctcctag gttcaagcaa ttctcctgcc tcagtttccc 120 aagtagctgg gattacaggc atgcaccacc atgcccggct aatttttgta ttattattat 180 tattaattat tacttttagt agagatgggg tttcgctaag ttggccaggc tggtcttgaa 240 ctcctaacct caagtgatct gcctgcctcg gcctcccaaa gcgctggatt tacaggtatg 300 agccatcgcg ctggacccaa agattggatc ttctgagaac atcagagaaa gactgtcctt 360 gccacccaca ttgcagcaaa actttcgaac cttgaactct gggttcataa tctcacaact 420 ga 422 <210> 793 <211> 639 <212> DNA <213> HUMAN <400> 793 acaattttac cagtgatcaa atgcagacaa cttgttgctt tatatatctt ccatttttgc 60 actgattgag aaagccttat actacctagt attttggagt tacatgccca aacataaggc 120 agttcaactc ctttcaattc ttagaggaag aaaccagtac attcttgtcg tcccattctt 180 ttcacatact ctgggtacaa cttgtcttta gatcaagggt aaatctgtga cactctctga 240 ttgatgtcta tgagttaagg caaactgtaa ctggcttaca gattcatctg tagaacaatc 300 tgtttcacaa gcccctcact tttctctgaa tgaaagtagg agttcatgag cccatctgct 360 aaaggatgta agggatttga agttgtgtct cagttgattc atcagcatgt ccctgaagtg 420 atctcccata agaaaataga agacagggtt gatgacactg ttcagaaagg ccaaaggccg 480 tgtcacaatg taaaaggagt tgatgacgac ctgagtgcac tgatactgct ttcaactcac 540 caggcgtgaa gcgatcctca cataccgcat gacgtgatat ggtgttaata gcacagagat 600 aattaccagt gccatgatga ccaagattga gaggcgttt 639 <210> 794 <211> 491 <212> DNA <213> HUMAN <400> 794 aaaagaaaaa gccccctttc ttcccttttc tgttttactt caagggcata ccttggaggt 60 gctcagagaa gcgtgaagtt tgcactatgg tggaggatgg ggaaagagtt ctaaagtgtc 120 tccagctgtg aacccaggag gtcaagtggg ctattaaaat ctaacgttga gtaaatgtga 180 tagtgatgag aaaggaattt tgtgtactgt aaccttgcag tagagatgca gctgtccttc 240 gtgtgtggaa acacacctct cctttacata gttgggaacc tcattagaaa tgacctcagc 300 tgccccatat ctacgttcct ttcagcagtt gtccaagtag gagtgtatcc agtgaagaca 360 tatcaaatca caaagtcatt gtcattagag tgtacttgat tactgggcat ccttgtaata 420 taatttcata ccactgacac atgatacttg taagagaaca tctttcccag agtgcctcag 480 accttattgc t 491 <210> 795 <211> 510 <212> DNA <213> HUMAN <400> 795 acgcgtccgc agcaagtaaa aataggagac tttggtctgg cctgcacaga catcctacag 60 aagaacacag actggaccaa cagaaacggg aagagaacac caacacatac gtccagagtg 120 ggtacttgtc tgtacgcttc acccgaacag ttggaaggat ctgagtatga tgccaagtca 180 gatatgtaca gcttgggtgt ggtcctgcta gagctctttc agccgtttgg aacagaaatg 240 gagcgagcag aagttctaac aggtttaaga actggtcagt tgccggaatc cctccgtaaa 300 aggtgtccag tgcaagccaa gtatatccag cacttaacga gaaggaactc atcgcagaga 360 ccatctgcca ttcagctgct gcagagtgaa cttttccaaa attctggaaa tgttaacctc 420 accctacaga tgaagataat agagcaagaa aaagaaattg cagaactaaa gaagtagcta 480 aacctccttt ctcaagacaa aggggtgagg 510 <210> 796 <211> 521 <212> DNA <213> HUMAN <400> 796 gccaatgatg ttgagcttta ttaatggccc ctctccagag gctgctcagt tgtccccagg 60 gaactcctca gagatcctct gccttcccac atatgagccc gaggacacct cgggagcaga 120 gaagtgaaag ggtttccggg tcagacgctg cactccacgc ctgcgtcctc ctcgtggctg 180 cagtcatgat ggccccagct attcttggtg cagctccaca gggtactctc cgtgccccga 240 cactgaacat tatccagcca gatctgccca gtgccagctc ccactttgta cagggccctt 300 cctttggagt aacccagcat gcggcagaag acaatggcat cagaattttg ccactcgtca 360 tcgcaaattg tcccccaggt accactgtag taaacttcag cccggcctcg gttactactg 420 ccgacaatcc tgacggacac tgagttttca cctctttcac ctttttctcc ctttactcct 480 tgctccccag aagatccttt cactccctgg tctcccttct g 521 <210> 797 <211> 646 <212> DNA <213> HUMAN <400> 797 gtggtgtcta agagtaactt tattgaaaat actaatcctc catgttactt ctgactggcc 60 ctgagtctgg gaaggccgcc aaagtgtcta ggtgatgtat tactctttat ggtagaacac 120 ctattcatta taaacttccc ccaatacaac ccctgttgtt gcagaaatct taggctgtga 180 caaccatagc tgcctacaca ttccttgtat cttggggtaa aagcacacgt gctctggaag 240 gaatgtgtag gtggctatgg gtgcacaatt tcagggggtt cgtgaactcc agttaagact 300 tgccctaatt ataccatgta aataattcaa taatgggcaa ttctgtagta gaaattttat 360 tcccacccat aaaatatatc actaaatagc tgaaaaattt acatattatt ttaaaacata 420 gacttaaaaa atcatattag cttctcctta gcaaaatgct tttgttttat gtatttacaa 480 gaatatactg tacttcaggt acacaattca ctcaagccag cctgagaagg ccttggatgc 540 agatcaatgc tccaataaag ttcattatca gctcctcctg ccttgtgaca ggatgatttg 600 attttacaaa agtccctttg aaaaacagag taaacgcaga cagctt 646 <210> 798 <211> 456 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(456) <223> N=any base <400> 798 tgcttttaca gnatataaaa cacttaaaat acagttgctt atttcatttc ctcagtaatc 60 ctagagagta tttcctgcat cttattgatg aggaattgaa gctgggatag cttctctcct 120 gactcttgaa gtccgaaaac aagtggacgg agctgtagca ctaagcctca gcctgctcgt 180 cttcaacctg ctcctggctg cagagtcttg attgactctg cctgtctcca gtgtgctttc 240 attcccttca gtgggtaact tgtcagacct cgtcttgttt ttgagacttt ggtttctgtc 300 ttgccttctt cctaactttg ggtattctta gttccaaatc ctgaataact cctgtaaatg 360 gggcctccca gtaggggggg ttcctgtatt tatattcaca gatgtacgta ttttaaatag 420 ttaacatctg gaaatcagta ttacatctta aagttg 456 <210> 799 <211> 421 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(421) <223> N=any base <400> 799 ttttttaaat tnaaaggagt ttaattgagc aataaacagt tcaagaattg ggcagccttc 60 ccagccagag taggctcgga cactccagcg cagtcacacg gtggaaggtt tgcggacaga 120 aaatggaagt gaggtacaga aacagctggg cttggctaca gcttggcatt tgccttatct 180 gaacgtggtt tgaacagttg gctacatttg attggccaaa actcagtgat tggcacaagt 240 gtagtctgtt tacacctcca cttgtcacga tatacagaca aacctttagg gccaaactta 300 aatatataag gaggcagctt taggctaaac tttatttcaa tacctgtatt ccaacacttt 360 gggaggccga ggcgggagga tcacttgagc ctaggagtta gagnttcagc ccaagcaaca 420 t 421 <210> 800 <211> 213 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(213) <223> N=any base <400> 800 gnaccaggna actctactat tagnagggac gactgccttc aagcatccct gcaactgcca 60 cagcaggtgg gggcagggct cgtgggaccc tctggacagc caccaagata tctgagcaac 120 caagagtccc agccccacca gtatctgctt ctgtagccca cggcacccca aacttggagg 180 gacctnccca ctcccttncc ccattcccaa agg 213 <210> 801 <211> 392 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(392) <223> N=any base <400> 801 gacagaatct caccctgtcg cccaggctgg agtgtaatgg tgcgatctcg gctcactgaa 60 acctccgtct cctgggttca aacggctctc ctgcctcagc ctcccaagca gccggaatta 120 caggcgcccg cactacaccc agctaatttt tgtgttttta gtagagacga ggtttcacca 180 tgttggccat gctggtctcg aactcctgac ctcatgatcc gcctgcctca gtctcccgaa 240 gtgctgggat tacaggcgtg acacncgtgc ccggcctatt ctcccagtaa ttcttgatgt 300 gtagggtgca tgggaagggc aggatgtttg aaatatgtat atttgtggga atgggttata 360 attgaggcta attaaggtat ggcctcatat ac 392 <210> 802 <211> 341 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(341) <223> N=any base <400> 802 ccaggaagcc cactgtaatt cgaattccag ccaaaccagg aaaatgttta catgaggatc 60 cacaaagtcc acctcctctc cctgctgaaa aacctattgg aaacactttc agtacagtat 120 ctggaaagct cagtaatgtt gagagaacta gaaacttgga atccaaccac ccaggtcaaa 180 caggaggttt tgtgcgagta cccccaaggt tgccaccgag acctgtgaat ggaaaaacca 240 ttccaactca acagcctcca accaaggtgc cccctgagag accacctncc ccaaagcttt 300 ctgcaaccag aagatctaat taaggaaact gcctttttaa t 341 <210> 803 <211> 513 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(513) <223> N=any base <400> 803 ttcccctgac tcccatctcc tagagggaaa cnntcattaa gagactggtg tatatcttta 60 tacattttac tgtcttattt gtagaaacaa atgtttctgt atgaaatcat tttttatatc 120 cttttctacc atttctttta taactcagct ctctctcttg ttctctctct ctgtatgtgt 180 gtgtgtatat atgtgtatat atacatatat atatatacat atactttaaa catcttttta 240 tggtgataga ggtgcatcgt ttttagcaat ttcgtagttg tcccctgtat gaagcagggg 300 gaaaggaagg gctagtttca tgactgaagc agagctgctg tttgggcaag aacatcatct 360 ttatttagct ttcataaacc atcttggttg tggaaaagac agcacagcca ggatgggctg 420 aaagtgcttg gggatgtcta atctgcttag cataagnacc aaccaagatt ctggagaaag 480 tcaggactca agagtatgca aatcaggnag ctt 513 <210> 804 <211> 425 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(425) <223> N=any base <400> 804 atctcttcaa ctggaatgac aacagattaa aaaaaatgtg caaccataag gacaccgtaa 60 cctatgagtg acatgctaaa ccagaaaccc aaaacaatgg gagtgacatg ctaaaccaga 120 aacccaaaac aatgggactg atgtactaaa accggaaccc aaaacaatgg gagtgatgta 180 ctaaaaccag aacccaaaac aatggaagtg acgtgctaaa ccagaaaccc aaaacaatgg 240 gagtaacatg ctaaaaccag aacccaaaac aatgggagtg acgtgctaaa accattaccc 300 aaaacaatgg gagtgatgtg ctaaaccgga aacccaaaac aatnggtaac ttaagagtga 360 ggctaaggcc cttacatttt ggtcacactc tcaactaagt gagaacttga ctgaaaagga 420 ggatt 425 <210> 805 <211> 446 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(446) <223> N=any base <400> 805 aaacatgtaa tcttgctccn tcaaaaacaa tttactctca aatggttcag aaaacaataa 60 cctgtatgta tgtgtgtgta catatatatg tgtgtatata tataggtata tataatgaaa 120 ttacatatat ataattagat atatattaga tctatatata gagatatgta aatgaaattt 180 cattatgtta acaattggtg gatatggaag agtatgaggg ctctttaaac cattcttgta 240 acttttctat aagtttgaga ttatttcaaa ttacgaattt aaagcagttc agtggtagga 300 agtgattttc atcttcactt ggtggtctgt tatgtgcctg cattgcagat atgattttga 360 ttcataagca tagctttgct tttctcagaa atcttttcct gctgagtcct cccttccctg 420 ccatccaagt acagaagaga gcactc 446 <210> 806 <211> 367 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(367) <223> N=any base <400> 806 aaatttcggc angaggtnga gaagagaatg cctgtgtccn gagataattc tgtaagnaaa 60 tgccagtccc taggnagaga gaaccaaaat gtctaccnga ccagatgtca aggctacagt 120 gggggacatt tccagtgatg gcaatttaaa cgtggctcaa gaggaatgct ccaggggaag 180 ggatagtggg atgaattctt cccgctgttg tcaaacttaa tgtatatggg nctcaaccac 240 aggggatatc cccagagctc ctatgnaaca ctaggcaaat tttgtgtttt tgtttcagtc 300 cgccatgggg ctggccctcc atctttgcag ctctgtaatt tttccaattt acaccccccc 360 aaatgga 367 <210> 807 <211> 401 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(401) <223> N=any base <400> 807 tgagccaagc cccacatgtc tgtgaaatgt ggtcttctag ccatagaagt agcttgtgct 60 cctagggtat tccttgaggc tctgtatgaa gaatgtccat ttgtttgagt ccctaaccta 120 cagaatattc ctgaccatgg aaatgtgata gataggagta agcacatgga ccaaaaggcc 180 tggaggctca tcatttaagg tacaagccaa ttatgtagtc tttgaaagaa tgctttgaaa 240 ttcagcttgc ttgattcaat tcccaatatt ttcatttgta ttaaaagatt tggcccttac 300 aggttaaaaa caatgtcagt gtaaccaagt gacatttcaa ntttgggctn cccaacatgt 360 ggatatgaca tcacttcatg tggaaatngg cgangtcccc a 401 <210> 808 <211> 422 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(422) <223> N=any base <400> 808 tnnnntnant agaattgcaa acatacttta gcctaagaag caggaagaga aaattatact 60 attctttaaa aagttcttta gtagcaattg gactactctt tccctattat ctaaatactt 120 cagtagtact tagtacttct ctttctccag aatctaattc acaagtaact atttgcattc 180 tatttccatt caaataaaca cttttacctg atcatattct gaagcaccag gggtaaagag 240 gccatcccag ggnacagctc agctatcaca cagcccagtg accacatatc aatagcttca 300 caaaatgggt aacccaagan taatttcagg agctctaggc aaaaacaaaa aatatccgga 360 ttaaaaanaa aaaaacntta tttgggggaa attaacttca tggncttagg tcccgttttg 420 gg 422 <210> 809 <211> 421 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(421) <223> N=any base <400> 809 aagagcctcc aggacagtaa ttccctgttt aaagcttccc tcttgatgag acattcttac 60 agattgtggt ccacagatga cctgcatcag aattgcttgt gatattgtta aaaatataga 120 ctctcagaga ggattgtagg aagatggcag agtagcaagc accagggaac ttttctcctt 180 acctagacaa taattgcacg ggcagaatct gtctgataca actattttgg agttcaggag 240 tctattgaag gcttgcaaat ttcagggaca gcttgggaca ataaagtaca gttaatttca 300 gtcagtttca ggccttaggc acagtaacag gcttctccat tcttcccngc caaccagccc 360 tggacaggng ctgtgcnatg ttttccccga aaaacttgca cacagcttta ggggccgggt 420 t 421 <210> 810 <211> 455 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(455) <223> N=any base <400> 810 tgattacatt ccagccaggg tgacagagtg agacccttct cagaaaaaag caggggagat 60 cattccctta atctgtgaga caatgacccc catcttccag tttatatcca agaacgaatc 120 aatgtagata caggaacaag gatcccgaat taggctacag gagacacaga tgccagtatt 180 ggntctgctc taattagcta catggcttta agcagtcatg ttacctttct gtctctgtgt 240 cttcaactgt aaaacaaggt gggttcacct ttactttcac accattacac aaaaatttaa 300 cttcagtatg gtattcagag ggctttaaat gcaagagctt aaaacttaac cacttttaaa 360 aaaaaaacag gggaaaaaaa aatcttttca caatgttngg ggttaggtta aaggntttct 420 ttagggatta ccaacaccca aagggcaaat tccat 455 <210> 811 <211> 386 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(386) <223> N=any base <400> 811 gcccaccttn gcctnccaaa gtnctggcat tgcaggctga gcacggtgcc cagcctgaac 60 accctttcct ggtaaaacac tccaaaacca ggaaaagaag gaatgtacag caacaaaata 120 aaggccagtc atgcaaggcc catggctgaa agtctttcag tcattttagg tgaaagactg 180 aantctttgc ctccaagatc aggaataaga gaaggatgcc cgatctcact acttctattc 240 aacacaggnt ttgaagtcag gctggtcaca gtggctcaca nctgtaatnc caggcncttt 300 tccggnagtt cgagggcagg tgggatttac atggaggctc ttgagtttgc agnaccaccc 360 tgggccnaca tgggccaana accccg 386 <210> 812 <211> 456 <212> DNA <213> HUMAN <400> 812 aaagacacag ttgtgcatgt ctggcacaac ctctcggcct gcaactgtgt ttagtgataa 60 tgatgaactg tgtgtgtgtg actttgaagg attctgtatg tcaagtgaaa aaaaatgatg 120 tctgacctcc ttacatatgt aaaaaatata ccttcagagt tcagcagtaa gctggaagaa 180 gtagatgtca aagaagtttt gaactttgat aataatgctt cagttattca ttcattgact 240 cggtggtaaa atagtcgaaa tggttttgaa tcagggttat gatagtgatg aagaaggtca 300 agataacacc acagaaaagg tgcttataga agaagacatg gtgaaaatgt atggtgggca 360 tattgaagga ttacggcagc gtgcattaac aacagaattg aaaaaccatg tcagttttta 420 aaattgaaga gagacttctg agctaaaaac catgtt 456 <210> 813 <211> 652 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(652) <223> N=any base <400> 813 gagaaaagga aaaatcaaat gagattccca ctaaaaatat cngaaggtca gatgacacca 60 tactatcctg tgggaatggg aaatggtaca ccttgtagtt tgaaacagaa ccggcccaga 120 tcaagtactg tgatgtacat atgtcatcct gaatctaagc atgaaattct ttcagtagct 180 gaagttacaa cttgtgaata tgaagttgtc attttgacac cactcttgtg cagtcatcct 240 aaatataggt tcagagcatc tcctgtgaat gacatatttt gtcaatcact gccaggatct 300 ccatttaagc ccctcaccct gaggcagctg gagcagcagg aagaaatact aagggtgcct 360 tttaggagaa ataaagaggg tgtcggttgg tggaaatatg aattctgcta tggcaaacat 420 gtacatcaat accatgagga caaggatagt gggaaaacct ctgtggttgt ccgggacatg 480 ggaanccaag aagagcatat tgaatgggct aagaagaata ctgctagagc ttatcatctt 540 caagacgatg gtacccagac antcaggatg gtgtncattt ttatgggaat ggngatattt 600 gtgatatant gacaacccag acaggtgact gtaaactaag tgcaagatcc gt 652 <210> 814 <211> 492 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(492) <223> N=any base <400> 814 acattctgag gtcctgcant tcagtgttaa catgtgaatt ttggggatac acaactgaac 60 cataacacaa actgtgaatt cttagcacct taagttgtag aagagaacag agccactcct 120 ccagccattg ctccaatggc tctggttaag ttgtagctca gtagagagca tgaatgctct 180 caaaaaagca ctacagttgt cctcggtatc cacagggggt tgcttcctgg atcccctcag 240 acaccaaaat gcacagacat tcaagtccct ggtaaaaaat ggtgtagcat ttatgtataa 300 catatgcaca tcctccccgt gtactttaca tcatctctac attacttgta atacctaata 360 aagtgtagat gctatnggag gatagttgga tataccggna attggttttt tnaaaattta 420 aggngaattt tttnaatggn ttgggggttt tttttccccc cgaaaaattt ttggggncca 480 tggaattgtg ga 492 <210> 815 <211> 458 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(458) <223> N=any base <400> 815 ctcactgaac aatgagacaa tgttgaggac tcaaatgaat caaaccccgt gganatgaca 60 gaagtgaaga atctggtccc tgtctttaag gagtttgcac tccagtagaa gacagaagga 120 acgtatgttt acaaaccact tcactggaag acgtcaaaca agctgaatga aggggcgctt 180 agaaaacgtt aatagaagtt ctaagcggga gatgactccc tactgggatg atgaaggatg 240 gcatcctagt gaagaagcag ctcaaacatt ttgataaaat ggcaacaaaa tgcagacacc 300 ctgctccagg tattatttca ggtttagtac aagtctgtta ataccctatg tggtttcatt 360 aggataactt tttacctatc cttgaggtca tccatattct tacaggcctt ccagtcaata 420 atggaagagc tcactctata caaaaccaat atgcaagg 458 <210> 816 <211> 453 <212> DNA <213> HUMAN <400> 816 aaggaatcgc ctccggaatg gtgagtccca ccaacaaacc tgccagcagg gcgagagtag 60 ggagaggtgt gagaattgtg ggcttcactg gaaggtagag accccttcct atgcaacttg 120 tgtgggctgg gtcagcagct attcattgag tttgtctgtg tcactgaaac tgaccccagc 180 caactgttct cagttcacag ccctgttttc aaagaattac acatctctaa aggcaaacag 240 ggcacggaca aggcaaactg gagaggcaaa ctgtagcctg agatggcctg ggcttgccat 300 cacaggtatt caggtgctga gggcccttag accaactaga gcacctcact gcctaggaaa 360 tcaatgaagg ggaaatgagt tctagcggac cctgaaggat cagaattgga taaagttctt 420 attggcagag aggcaccagg attgaagtga cag 453 <210> 817 <211> 260 <212> DNA <213> HUMAN <400> 817 gcacccacac tggcgagcgg ccctacaaat gtccccgttg cggcaaggcc ttcgccgaca 60 gctcttacct gcttcgccac cagcgcactc actctggcca gaagccctac aagtgcccac 120 attgtggcaa ggccttcggc gacagctcct acctcctgcg acaccagcgc acccacagcc 180 acgagcggcc ctacagctgc accgagtgcg gcaagtgcta tagccagaac tcgtccctgc 240 gcaccatcag agggtgcaca 260 <210> 818 <211> 473 <212> DNA <213> HUMAN <400> 818 caaattcctg actataatgt agcataagaa ttggtttttt atgccccaga gagaactcat 60 cagtgaaatt aacaaaactt acatttaaaa taattagtat gaatgttaat gatcccaagt 120 aaagttttta aacaaaataa gcaaacattt gggcctcaga ataagcaaat ttaatacatg 180 gacattcaca attagaatat aagttcattc tgagatattt atttactttg cagaaaattc 240 ccttccccat ggaattgctt ttgaaaatgt gatctcttca agcatttgaa gtataatttc 300 attaaacaca cataaccaac ttatattgtg taaattaggg ccttcctgac taggcacaaa 360 actacctgca tttagtttaa atatgatctc tttaaaaatt tgtaaattag gcacctgccc 420 tcccccaaac acctttactt accccagctt gtggaattga ttccctctgg ctc 473 <210> 819 <211> 151 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(151) <223> N=any base <400> 819 gttctttgca gggctattaa tatctaaatg attattaatg caaggatggt aaatatttgc 60 tcaataatat attaaattac aatgagggat gaagttctct anagatcgta gaagtggcac 120 ttcttatgac ctctggtttg caacttttaa g 151 <210> 820 <211> 465 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(465) <223> N=any base <400> 820 ttccttttca gttgtgtgtc ttatcttgat tgggtcatga gaaagttnca tcttagtgct 60 actgtgtctt gaacgcctct gggtgggaga acaggcctta ggcttagagc ctgcagcagg 120 cagcagtatc ttgctgggtc ttaataacat tgttttgctt ttatctttat agttaccttg 180 tgtttatgac aaaccttcaa aaagttttaa attttgaaac attgcataat ataaaaatgt 240 ttttatttaa gaaggtgagt agatttgaag aaaatacaca ttgagtatta tctaaaatgc 300 ttgggacaag aagtgtttca gattttggat tttttttttt tgattttgta atatttgctg 360 tggagcgttc cctaatctga aaatccagaa tgcnccagtg aacatttact ttgaccatgc 420 ctggctaggt tttttttttt ttggaatttt nannagaaan ggggt 465 <210> 821 <211> 129 <212> DNA <213> HUMAN <400> 821 aaccaactca gaccagaact gttttctcaa cctgggactt cctaaacttt ccaaaacctt 60 cctcttccag caactgaacc tcgccataag gcacttatcc ctggttccta gcacccctta 120 tcccctcag 129 <210> 822 <211> 201 <212> DNA <213> HUMAN <400> 822 ccgggagcag cgccggcaag tggagtcgtc gtattccggg cggcccgcgg cccacgggga 60 tgggacgtcc cggggctgtg ctgaccccaa aacccttcca cactttatta gcctgtcgcc 120 cttctttcat gtttacagca aatattttcc gagtgcctaa tgtgtcccac ttactgtgcc 180 acgtgcgagg gtgcacgtgt c 201 <210> 823 <211> 136 <212> DNA <213> HUMAN <400> 823 ggatgaattc agaatctttt tcattccaaa acttcctgca tataatggta gcaacccaca 60 atgagacatt cttttagttt ctaaaagcag gaaataagca ttttcctgaa agtttcctca 120 tctcttcatc atacac 136 <210> 824 <211> 109 <212> DNA <213> HUMAN <400> 824 ataagacact gtactttgac gtggagccgt tcgtctttta catcctgact gaggtggacc 60 ggcagggggc ccacattgtt ggctacttct ccaaggagaa ggagtcccc 109 <210> 825 <211> 329 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(329) <223> N=any base <400> 825 gtcagatgga ggaggctcag aaaagggaag ggggtcatat agaggaggcg caganaaggg 60 aaggggctca gatggaggag gtgcagatnn ngggaggngg tcanatggag gaggctcaga 120 gaagggaagg gactcagatg gnggaggggg cgcagagaag agaaggggct canatggagg 180 aggaggcgca ganaagggaa ggggctcaag atgggaaggg ggccctggaa ngtctcggct 240 ctncttctgt aaaatcnggg gagttttcag ggtgaaggga ntncagtctg cangctggga 300 tcccccctaa tttncnancc ggcttgctc 329 <210> 826 <211> 248 <212> DNA <213> HUMAN <400> 826 gtggggctgg tgcccgtggt gggcggcgaa gagagctggg ggggtcccct gctggccgcg 60 gctgtggcct atgggctgag cgcggggagt tacgccccgc tggttttcgg tgtactcccc 120 gggctggtgg gcgtcggagg tgtggtgcag gccacagggc tggtgatgat gctgatgagc 180 ctcggggggc tcctgggccc tcccctgtca ggcttcctaa gggatgagac aggagacttc 240 accgcctc 248 <210> 827 <211> 228 <212> DNA <213> HUMAN <400> 827 ccagtgggga gaaagtcggc cagacatcac tggaggaaga aagaggaggg gggcccctat 60 taaccctggg cctcctggct tctctgtcgt caccgcagag ggagtgtggt gattgagaaa 120 caagacagct tcaacaagac cggcagtggg gtatgactca ccttccagaa gccaaaggca 180 aagaccagac cgctccccaa tactctccta aaataaacat gaagcact 228 <210> 828 <211> 424 <212> DNA <213> HUMAN <400> 828 tgcaaagttc agagatcaaa aatgtctccc aagttttccg gcaacaaatt gccgaggttg 60 tatttgagtc agttacttaa ggtgttttgg tccccacagc catgccagta gcaacttgct 120 tgtgagcagg cctcagtgca gtgggaatga ctctgccatg caccgtgtcc ccggccgggc 180 ctgtgttgtg caatgctgta catcacaaca ggagggtagg gggacaagag agcacaggtc 240 ctggcagctg ccacagtctc caggggcttt tgcgtttctc tccagatttc taaggttaac 300 atggggatta gctgttttgc aatgaataaa aggtaacatt gcctggaatg ttgcttaaag 360 acactttttt aaagctagtt gattgttaag ctgttgctac ttaaattgaa aaactacttt 420 tggg 424 <210> 829 <211> 209 <212> DNA <213> HUMAN <400> 829 ggagcattcc aggagagaaa ggtgagtggg ctgggtcagt tgaggacttt atgaaagggc 60 cgtggtagtg tgtcctgtca cagcaatgaa gaagaatttg gcaatagaag tcacatttgg 120 tgcagaagtg gtagacatgg aaacagcaca gtgaacagct ggacgaggct gaccaagaga 180 actgtcctga gggagtgagt tttcactgc 209 <210> 830 <211> 211 <212> DNA <213> HUMAN <400> 830 cctacttgcg acaaggtgga cttgggagga aagccgtctg ccaaagcctg aagcctccaa 60 gttctgtagt tcaggaacct tgtctgttgt agcagggata aaacccacaa gaacatggat 120 acagaacagt tttggaatga acattgccag tgctacaatt gcactagtgg ggactgcttt 180 tctctcacta aatatagcag ttaatatcca g 211 <210> 831 <211> 308 <212> DNA <213> HUMAN <400> 831 gtcgggcttt acggcgccgg atggctctgg acgtgaagtc tcgggcaaag cgttatgaga 60 actggattcc ttggggaggg acagtttgcc accgtttaca aggccagaga taagaacacc 120 aaccaaattg tcgccattaa gaaaatcaaa cttggacata gatcagaagc taaagatggt 180 ataaatagaa ccgccttaag agagataaaa ttattacagg agctaagtca tccaaatata 240 attggtctcc ttgatgcttt tggacataaa tctaatatta gccttgtctt tgattttatg 300 gaaactga 308 <210> 832 <211> 240 <212> DNA <213> HUMAN <400> 832 cgtcaagacg ggacccagcc agcatgcgtc gtgacagctt ggggcattgg aggtgggtgt 60 tagtggttag aagaaacttc ccagcagagc gggttgctgg agccaagcgc gcatctgtca 120 agaatgctct ctgggcgctg ttcttgcaag gatcctctgt tgaacctcga gtgcagtaga 180 tgtggaaagg aagcgaaggt ttgtgcatct aacagctaac gctgagggcc ctttggaatc 240 <210> 833 <211> 381 <212> DNA <213> HUMAN <400> 833 aaactttact gaaataaaca aacaagaaaa ctggatgagg tctccatctt gttttatgtc 60 ctcgggaatt tgactttgtg agaacatggc ggtactttct cttggtctcc ggcttccaag 120 gaagaagaat tttaaagttc atgtcatagt taactctaaa aattacctta agtagttaaa 180 agcctttaca agctcaaaat taactactct agactccttc cggaaagggc aatataaacc 240 acccagtgct gtaactcagt aactaagatt ttgtcctttc atagtgacag cccaggttca 300 attcctgact taggaaataa gtcctttctt gtttaatatc tgcataacca ttaccatttg 360 ttgattgtct tccccttctg t 381 <210> 834 <211> 164 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(164) <223> N=any base <400> 834 tgctgtgtca ctggccatgg ttactcatat ttggcttaga ataaatctct tcaaannnnn 60 nnnnnnnnnn nnnnnnnnnt aaaggaaaaa caaatgcttt tgcagaagcc aagaagaaag 120 tgaagggaaa taaatgagag tggaaaaacg agagatcaat tgtg 164 <210> 835 <211> 324 <212> DNA <213> HUMAN <400> 835 atcctgatac ttcgctccta aatcatcttt ttttccctaa gtcttttgta tgcaccacta 60 aaaaaaaaaa aagccatttt tcctgcatga cccaacagaa tgggctgtaa ttagcttgta 120 atatatgcaa atgtccatct ggattctgac ttcccaagct gcatggctgc cttcatttgc 180 aggggggagg tttgctgcag aggggggcag catcagcagg cgtgtggagt gagtgagccc 240 cgtcctcccc ctcctcctga cattggctct cattgcctaa cccccttgtg tcttggcccc 300 aggttgattt tccgggggta ccgc 324 <210> 836 <211> 295 <212> DNA <213> HUMAN <400> 836 ggatggactc ccagcaggta tgggacaggt gccaggtgtg tggtggggac aacagcacgt 60 gcagcccacg gaagggctct ttcacagctg gcagagcgag aggtaggcgg cctccctcgg 120 ggcagaagct gggcttcccc cagcctccaa gatggccaca gcccagagcg ttggtgcagg 180 ggctgctcag gtcacagggc ctgcacactc actcagccct ggatgcctcc tgtggtgtca 240 gcgtctccct cttccacttc gccacccttc tgtggcaggc tcaggttttg gcctt 295 <210> 837 <211> 375 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(375) <223> N=any base <400> 837 tggagaacag gtgtgagaat ggcatggcat atacagggag ggaaggatgt attaaagaag 60 annnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 120 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 180 nnnnncatgt acaacattgc ccatgatgtg gaagtcaagg ggcaggtcag cgctgtaggc 240 cacataggct atggcaatgg atgattagta ggtgcccact accgggagat gggagctgca 300 ggtggagaag gctttggagc gtccttcttg ggagttaatg cgaacgaccg aggtcaagat 360 gtgggcatag gagag 375 <210> 838 <211> 221 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(221) <223> N=any base <400> 838 gaggtttcac agcaaaggcc ccaccctcaa gcctggaaac ctgcagccct aaatgagaac 60 aggcattcct gtttttgcgg ccaaannnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 120 nnnnnnnnnn nnnnnnnnnn nnnnnnnnag ctccactggc agagcancaa aatggtncag 180 cagngaaata gngaagaggn gaagcntntn aacatgaaga a 221 <210> 839 <211> 150 <212> DNA <213> HUMAN <400> 839 gcccccaaca actgaatgga cccccttgcg gtcaagggga caccagtggc aataagatac 60 caaattatga ataggaccta aggtcatgcc aggcaagggt taagtcacac accctacatt 120 taaactatat tcctactgcc acactgcttt 150 <210> 840 <211> 78 <212> DNA <213> HUMAN <400> 840 aagtccccca cccttggaca tttagatttt ttccatcttt ctgtatttgc agatatgctt 60 ctacgtacac ctttattc 78 <210> 841 <211> 117 <212> DNA <213> HUMAN <400> 841 acacacatgg agctgtcatc gcctgtggta acaatgcctt ctacagtact tcccaaaggg 60 cctgctagtt cacttaattc ttttatagag agaaggagta cactctaaca ctgatca 117 <210> 842 <211> 126 <212> DNA <213> HUMAN <400> 842 gcagtttgcc ctccgctcac gcagagcctc tccgtggctt ccgcaccttg agcattaggc 60 cagttctcct cttctctcta atccatccgt cacctctcct gtcatccgtt tccatgccgt 120 gaggtc 126 <210> 843 <211> 443 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(443) <223> N=any base <400> 843 ctccagacag catgaggctc cctcgaaccg cccccatcaa atgctcatgt caggaaatca 60 tctgatatat gaattcacat cgagttggca atgcctgata aggcttgggg tgacctctcc 120 ataggggatg aagtcaagat ggcagtcaga accacaaggg aatggctcag ggataggtgc 180 ctggaaaggg tcacattttc ggaaatccta gtcttcagtg tcctggatct gtatgcctta 240 ccattttcca ttcccagcca gaaatgctca aactttgctg tgttcctgat cttgctcctg 300 actcgtatga gtgtgtctgt gaaagccaag attaactcct ttgattttgt agactgatgt 360 gcnaatctgg caggtctgac tttcttagct gtgaagatgc ttgggcacaa gtaccaagac 420 tgatctgctt nctgcgtgtg aca 443 <210> 844 <211> 91 <212> DNA <213> HUMAN <400> 844 caaccatcag gagtgcctca agggagaaat atcctctgag aatagccaca gacaaagtgg 60 ggaggtggga ctacaatccc cagccctgga a 91 <210> 845 <211> 245 <212> DNA <213> HUMAN <400> 845 aaactaaaga gagaggatag ataagacatg ctgcagttct tgccctaact ttcaatccca 60 acaactgaaa tgtcttccag agaagtaact ccccccggta gggatgtagc gcggtcccta 120 cgtgggtcta agggatctga cccacgacgc actgcactgg gttcacgaag cgcctcctcg 180 caggcggtta tctcggtatc tctgagagcg gcgggctctc gctcccgctc cagggattcg 240 gggca 245 <210> 846 <211> 355 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(355) <223> N=any base <400> 846 atgtgagctc tcctccagct tcccagcagc aaccactgag cacttaccct gtgctgggtg 60 cttgctaaac actttacatg catgatctca cagaattcta ataataatcc ttcacttatt 120 atcaacttcc cgagaaagga aagtttaagc agctaaccct tggtcctaca gctggatggc 180 agctggtaga gttgagacat ctctcttgcg ctagacaggg aatgaatctg agtgaaggct 240 aagaggatgt ctgcnnnnnn nnnnnnnnnn nnnngacata aactaatgcc tacagctagc 300 taattaacca atcaccatca gttaaataac ttttagcaag aaattaacca gtcca 355 <210> 847 <211> 432 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(432) <223> N=any base <400> 847 gtggtgtggc tgcagtggag agttcccaac aaggctacgc agaagacccc ccttgactga 60 agcaatggag gggggtccag ctgtctgctg ccaggatcct cgggcagagc tggtagaacg 120 ggtggcagcc atcgatgtga ctcacttgga ggaggcagat ggtggcccag agcctactag 180 aaacggtgtg gaccccccac cacgggccag agctgcctct gtgatccctg gcagtacttc 240 aagactgctc ccagcccggc ctagcctctc agccaggaag ctttccctac aggagcggcc 300 agcaggaagc tatctggagg cgcaggctgg gccttatgcc acggggcctg ccagccacat 360 ctccccccgg gcctggcgga gccncacatc gagtcccacc acgtggccat ctcagatgca 420 gaggactgcg tg 432 <210> 848 <211> 456 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(456) <223> N=any base <400> 848 aattgccagc ctatcgaggc taganatatc tcctgatcct tgggaatgcc tttactgcct 60 gggttgaagc ctctcatact agaatagaaa agattcaggt agttgtcaag atcattctga 120 aaganattat ctctttgagc ctccacagtc ttcacaaagt aacaatggcc tatattttat 180 ttcacaaact acccaaacng tggcaaaagc cctagggata taatactttt cacactcctc 240 ctgaaancca caatcttcca ggaaggtaga naggactaat caagctatta aaaggacctc 300 gagcaaatga tgccaggnag cctctttacc atggctaaaa cttctaccca tggcacttct 360 tcagatcaga acagccctta aattacgcta tggctagttc tttgaagcct atactggaga 420 cctttctaca tgcnaancta tattataccc agaggt 456 <210> 849 <211> 474 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(474) <223> N=any base <400> 849 aagataccca gattgtcact gaaagagact caccgtctat ccttatctac ctttttaagt 60 ccttttaggc agtattataa agcactaaat ctctaattaa agnnnnnnnn nnnnnnnnnn 120 nnnnnnnnnn nnnnnnnnnn nnnnnnnncc tcagattcca aatccagaca ctcaaatccc 180 ttatataaaa ttgtatagta tttacataca atctatgaac atcctcccat agacnnnnnn 240 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 300 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 360 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nngattagga aagacaaaag 420 tccgtgatat gagataatac ctcaattttt taagtggttc tgaacattcc tgag 474 <210> 850 <211> 529 <212> DNA <213> HUMAN <400> 850 taccctgctt cacgtgccta agtctggggt cttttctcat aacccctcct ggaatctgag 60 ggagaatcca ggccagctcc agtaaatccc acccatgtat ccttttattt ccatctgaaa 120 agagtttgga atgaaacaag cgttttcaga atgagcttcc tcacaggact ttgtgcttat 180 catgctgctg ttttagcttc tccagtcctt tctcactcta tccctcaccc tttctgggtc 240 actgacagtc cagcttcccc ctgcaaagca tcctgggaaa acttgagttg tgttcccaga 300 gttgacaagt cctttctgat ttcagatacg tcacactgtc aaatggaacc tgcattttta 360 cccccctttt cagctggcgt tggacatctt tgaggtgtcc tgaagaggag ggtggttatt 420 tggagactat cagtggaaat gaagagctca gctgatggct gtagatcctc acccacatgg 480 tccctcagcc ccgaaaggtt ttacttgagg gctggttcct atttgataa 529 <210> 851 <211> 402 <212> DNA <213> HUMAN <400> 851 aggaattaaa agaaaatatg atttaaatga cttgacaaat agggaatcta aatagtgaaa 60 tacaaactat aaaaagaatt aaatggaaat tctggagttg gaaggtacag ttaccaaaat 120 taagaattca ctagatgggc tcaatagcag attttaagat agtggaagaa ccagtgaaca 180 tgaaaataga ccaatagaaa tgatccaatt tgaaaaacag agagaaaaaa atgaagacaa 240 atgaacagac cttcagacac acataggatg atgttaaatg tccccacata catgtaatgg 300 gagccccaaa aagggagaga caaaaatatt gatgaaaaat attgaattgc agattttttt 360 aaaaaaagct caaccaacac tgacttttat aaaacagaaa ga 402 <210> 852 <211> 216 <212> DNA <213> HUMAN <400> 852 attaggtggc agagccagct ccactctgcg tgtgcccccg actctattcc gcttgtgagc 60 cccactcgga aagtaggcag cggtccggac ttcccttaga gtcttctaac ttaaaaatcg 120 ggcggcggca cattcctggg aaagggaatg tgtcttccct gtgaatgtgt ctttcctgtg 180 aatgttctct gcaaaagtca gatagcttaa tcagac 216 <210> 853 <211> 278 <212> DNA <213> HUMAN <400> 853 cctcgccagc acagggtggg atcagacggt ctgatctgtg ccagtcaggt ggaagagtcc 60 tctcgtaggt ttgcttggca tctttctgtt taaagtcaca ttgggtggtt aaggagccac 120 caaacgggct gcccatctcc tctgctggac tggagccaag gcaagagacc tggctgtgtt 180 gggcatgtcc tttctgtagc taaagtccct ggagacccca gtgacctgag agtcgggcag 240 atcccaggag gtcttctggg gtggtctctg ttcaaggg 278 <210> 854 <211> 497 <212> DNA <213> HUMAN <400> 854 ataaaaaatg ggtctctgat gacgaatctg gttatatggc accagcagct gaggccaaaa 60 gcctggtagc ctgccaccaa gtgtaccccg aaagaggggt gtgtgggccc gagtcacctg 120 ggtggtcctt tcaggatttg tggctctgag gtggcccctg gtgctggcat ttggggaggt 180 ggaggggata gagggaagac attctgggcg aagagtggaa gatccatagg ttcctcggtg 240 accctcatgg ggacagtaca cccgggagat tcatgttctc caggtacccg gagctcacgg 300 actgaccctc ttctcctgcc tcctctggcc tacgtgctcc gggtagatcc actttccttg 360 aaggtggggg tggtggctgt tgggcctggg gaatcttttg ctgtttactt ggggaggctc 420 aggctctcac ggttgacctc tgcccagtta gtttcatgta agtagagcaa cctagtttca 480 cgaaggaagc accaggc 497 <210> 855 <211> 353 <212> DNA <213> HUMAN <400> 855 aaaataggta ttaataagaa aaagtgatga gtaaagtgcc agtgaccaga aatgggctcc 60 tgtgtaggct gccagctgga taataaagcc ctgaataacc aataagtgag catgaaagta 120 aaattttgaa tgttcattat gtgtgactag cttacaactg gccttttcaa gacaatatga 180 tagttttaaa tctttatttt tcttttattt acaaacttat ttacttttca ggtgtatgaa 240 atctgaagag aagtcccttg gtgtgggatt acatacattt tgcacaagag tatttggtaa 300 aaatagttat tttttcccac atcctatcag aacaatatta ttcttattat ttt 353 <210> 856 <211> 421 <212> DNA <213> HUMAN <400> 856 cgtggacatc gtgggcccca ctgggggcat catccactcc tgccaccgga ctgaggagaa 60 cgtgaccggg gagcaagggg ggccagatgt ggtacaaccc tatgctgcct atgctccttc 120 tggaacccca cagggcctcc tcgtctatgc caaccggggc gcggaagaag actttaagga 180 gctacagact cagggcatca aacttgaagg caccattgcc ctgactcgat atgggggtgt 240 agggcgtggg gccaaggctg tgaacgctgc caagcacggg gtagctgggg tgctggtgta 300 cacagaccct gccgacatca acgatgggct gagctcaccc gacgaaacct ttcccaactc 360 ctggtacctg cccccctcag gagtggagcg aggctcctac tacgagtatt ttggggaccc 420 t 421 <210> 857 <211> 276 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(276) <223> N=any base <400> 857 ggtgcacgca tctcatgtct gaatctcctc tttctccctt ctttctttcc tccctcccaa 60 gcttacatac ctttgttacc ggctggtgtt gtgaagtcnn nnnnnnnnnn nnnnnnnnnn 120 nnnnnnnnnn nnnnnnnnnn nnnnnntgta gcaatgcagc aagagactta ttaagcacag 180 taacactctc agagagggga gaacgggctg acttctgcaa aatgggatca gcgtcagttt 240 ggtgaacttt gggctttggg tctttttaca tgtttt 276 <210> 858 <211> 102 <212> DNA <213> HUMAN <400> 858 gcgttctcct agaagacaga attcttacat gccccgtctc catctagcag gaaaagccat 60 atcttgcacc agcagcatga atggtccctc cacactctgg gc 102 <210> 859 <211> 236 <212> DNA <213> HUMAN <400> 859 attctgtggt atccatcttc tgaagctgaa cttggtcgct aagcaacaaa gcagatgtga 60 aactgtgtgt cccttattag gtgtctccta ttaggcagaa aggagttgta aataagcaaa 120 atagtggtaa aaatttttgg tagcagttta gtagcacagc atcttcataa tgctatatgt 180 tttttaaaat agtattttat ccatagcaca aaaggtgcct aagataagaa tttctg 236 <210> 860 <211> 192 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(192) <223> N=any base <400> 860 gaanaagtaa cagacaccat cagcaggtgc ctcactcctg atgtggaagc tcgtccagat 60 attgtagaag tcagttcgat gatatcagat gtcatgatga aatatttaga caacttatct 120 acatcccagt tgtccttgga aaagaagcta gaacggganc gaagacgcnc acaaaggtat 180 tttatggaag cc 192 <210> 861 <211> 185 <212> DNA <213> HUMAN <400> 861 gcccgtgggg tgcaaaagat cctgcaggtg agtatattac tatgtgggat cagtgtctcg 60 aaagtcaaaa agagggcctg tggggactat atgaggactg gatctttctt tgtgatttgt 120 tttggagcaa ggaaagttga ggctggcaat tgctagtgag agctaatgag gtctcttgag 180 tttcc 185 <210> 862 <211> 541 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(541) <223> N=any base <400> 862 gggtacctgc ccatttctgg gcttttacat aaaaccctgt aagtgggttn tggggacagc 60 tgtgtaacat gcacaaaaaa taaatggagg aagaatgcat tatctaaata ggcactgact 120 tgcgtgattg aagctgtaac catcctttgc agcccagagt tgctgtgacc tgtgtggaga 180 ggtgggaggg ccaggcagag agtgggtgtg aaagccacgg aggatcccag ggagtggatt 240 cctaagtagg aggcgaggca ggtcatcagt gaggatccca gggagtggat tcctaagtag 300 gaggagaggc aggtcatcag tgaggatccc agggagtgga ttcctaagta ggaggcgagg 360 caggtcatca gtgaggatcc cagggagtgg attcctaagt aggaggcgag gcaggtcatc 420 agtgaggatc ccagggagtg gctgcagtga ctgtgcccag caaacctcct taaggccctg 480 ccctggtgcc tgcggctcta ggagattccc tgggtagtcc cagcacacgc aacctgttca 540 g 541 <210> 863 <211> 150 <212> DNA <213> HUMAN <400> 863 ctgaataagc ctctgatccc gcctgcatgg gccagccccc taagccatct gtgccctgca 60 ggccacactg ggatccaatg tcccactctg aaccccagat atcaagctcc acagcagaac 120 agatttatag taattctgaa acttttcaag 150 <210> 864 <211> 483 <212> DNA <213> HUMAN <400> 864 gcaggcccgt ggctctcctg ccctctgcat gcatcgcgag tactgccgga ggaggcccct 60 ttggctttca gagcccagag cgcccgacct cctccaggag tctgcagatc cacaggcctc 120 agatgctgcc acacccaccc agcacacacc caggtctctg acacgccagc cgcacacagc 180 ggtggggttc aggcgaaggt ttcttccaca gtgcagagta gaagagccgg gaaggacccc 240 atcaccatca gatgcatcag agcttcaaag gcccgcccat caagacgctg ccaaggagca 300 tgaggccagc caggctgggg aggacgttgg cgagcatccg cctgcccgtc agggagccac 360 agctggatga tacatcgaca gacagcagag ggacggtgta gcacacaggc gagggcttgt 420 ccccctcagc ctgggggagc gccgctcagt gcttggtggt cagcacgtga ctgacacttt 480 gcc 483 <210> 865 <211> 218 <212> DNA <213> HUMAN <400> 865 gagccaggga gagtgctttt gggctccagc cccatggtaa cgtctaggag tgtgttacaa 60 ttaatgctct tttagtagtt gccatctaca gatggctaag tgtgtaagtc agagtgaagc 120 cttttacact ctgccctctt gttacctgag tccttgtctg gcatccagga aggataaggt 180 cacacatgga cttgagggtg gtgaatgcag aggtttta 218 <210> 866 <211> 519 <212> DNA <213> HUMAN <400> 866 atttatttca gtcttctgtg tctggcttgt ttggttttca gtgggtatgt ttgattagag 60 attgtttgta atttacctgt ttaatttctt ttttgttctc ctgctatgtg gctgcctcct 120 ttttggcact agatggtgct ttaatccctg gttcatcttg gctctagtaa acctttctct 180 tgctctctca atctctctct ttctctctaa tcttttatgt tttctactaa attatgagca 240 ccaggggcca tgttattagg tattttttta tgcttggtaa atatgtcttg ataattacat 300 gtgggtgtat tgtataataa gtatgattta agtcaccaag gtaagggttc ttaagctggg 360 tcccataaac tccttgacat gttgtgtaaa gttgtatgtt atatgcatgt atgcattttc 420 tggggtgtag gtctgtgact ttcattacta cctacttcat gttcatactg tggttaagaa 480 ctatggtagc aagacaatat cagacatatt ataaatact 519 <210> 867 <211> 491 <212> DNA <213> HUMAN <400> 867 acaaatcttt ctcttagaaa aatatgttct taatattgca tgggatatac ttatactaaa 60 aaattatttg ttgtttttct gaaattgaaa tctaactcgg agtcctgtat tttatctgag 120 agccccagct ggggacgggc gcggggccaa gagagctgcg agggaggagg ggttgcaagc 180 ttctttcggg cggaggggtc acaaggcgaa tggagaaggt gacaaggagc atggagaaac 240 caagaaaagg gctaacgctt ggagagcaag gatggaaaga cgctcaaagc ggaggcggaa 300 cggtctgagt gattccaaaa ctagtgtgtc caagctggtt agaactcagg caggcgggtc 360 cagaagccga ggggcctgac agatacgcag gtgaagtcca tctgtggtcc gcgtgctggg 420 cgtgggcacc gggctagtcc aagcattcct ggtaaaggct cctccagagt ggtaccacag 480 cgctctatta a 491 <210> 868 <211> 465 <212> DNA <213> HUMAN <400> 868 ggaggcacaa aggtgaataa actcatcaag gagcttacag tttaatgggg aagacagaga 60 cattatcagg tacttaaaaa atatgctgaa gaccttagct aaagaaactt tagaaatcaa 120 taatatggag ttttccccaa aactaaaaat actctgcccc cactgtgttc acaagatcag 180 catcaagcaa agattaatct caagacttgt tgtttttctt gttgggtttt ggacttactt 240 gcaacccctt tcttcttatt tctccctttt ggaatgggaa catctatcct atacatgtcc 300 caccattgta ttttggaagc acattaactt gtttgatttc atgggttcac agctggagag 360 cagtttgcct caggatgaaa caaacctttg agtctcatct gtgtctggtt tagatgagat 420 tctggttttt ggacttttga gttggtgctg gaagaagtta agact 465 <210> 869 <211> 515 <212> DNA <213> HUMAN <400> 869 ttttaaacat gaattttcta aatattatgc caagtaaaat gagctagaca caaagggaca 60 aatatcagcc aggcgctatg gctcaagcct gtaatctcag cacattggga gactgaggca 120 ggtggattgc ttggattgct taagtccaga agtttgagac tttacaagaa atacatatat 180 tagccaggca tgcaccttgc taatagtccc agctacttgg gaggctgaga tggaaggatc 240 accttgagcc tgggaggtcg aggatgcagt gagccgagat tgcacccctg cactccagca 300 tcctgggaaa cagagtaaga ctctgtctta aacaaacaaa caaccaaaaa aaaccccaaa 360 aagctaagaa ggctcggctg ggcacggtgg cacacgcctg taagtcccaa cacttcggga 420 aggccaaggt ggatggatca cttgaggtca ggagtttgag accagcttgg ccagctggtt 480 tgagaccagc tcattttgta cttttaggta gagat 515 <210> 870 <211> 543 <212> DNA <213> HUMAN <400> 870 ttgatggcca aacaggttta tttacaagaa taagcctgtg aggggtccca gtcaggaatg 60 tggctgagac cctgtcactt agaaactgag gtttttataa taaagtttct ataggggagg 120 gtttgcgtaa gtgctggcag gttggaactg ttgggggctg gagaaggatg tggtaagggc 180 catcaggctc tgttgtggtt agggttgtta tgctctatta aaagtatggg caaggttgac 240 acctgctttg tttctgggaa caccgtcacc aaggtagaaa acagtcacca atgtagagaa 300 atggcatcgc tcttgttagt ccccacattt ctttacagca ttgtgagaag ggacgaatac 360 aggagccata gatttcaagg gtcctccctt acccctcctc agcccacgtc tgcagggcct 420 ccgtgctgca ggcaaacata ggcccctgaa ggagatcaca tcagacatag gcagacaggc 480 acatggtcca aataagtgcc tgtccaccag tggggacctg atgttccagg cccagtggct 540 gca 543 <210> 871 <211> 372 <212> DNA <213> HUMAN <400> 871 aactttttaa aaagcaaatg tattcttcct ccattatcta aaaaagattg gcaaaaagtt 60 aaatctcctt ttacttcaaa agtaaagaaa atcatgcaat gagatgatcc tgttgggcct 120 tcagcacaga cccatcctct cttccccggc tcccagcagt ccagggcagg tttctgtcct 180 cagcaggctg agttttgttc agtccattcg ttccttgctg gatcagcaca ctctggattt 240 ctcagccctt tcagtctgag tgttcctccc tcatggcctt cacaagccag tcctgttctg 300 tcccctgctc agagtcactg gtgtcactca cctccatgga cagcagcttc gagtacttga 360 ttttccgctc tc 372 <210> 872 <211> 380 <212> DNA <213> HUMAN <400> 872 tttttttttt tttttttttc cggattgagg aactctctgg aactgtcttt cttcaagaga 60 gcatttctta taatacagat ctggtagtgg tgaattctct ctgcttttat ttgggaaaaa 120 ctttatctct tcttcatatt tgaataatag ctttgcttga tacagtattc ttgtatggcc 180 ttcatggttt tgattgagaa gtctgtggcc aggtaaatta gagctctttt aagtgttatt 240 tccttctttt ctcttactgt ttctaggatc ctctctttgt tcttgacctt tgagagtttg 300 attattatat gccttggggt aatcaaatct atttggtgtt ctctggcctt tctgtacctg 360 gatatttgca atttttgaat 380 <210> 873 <211> 13509 <212> DNA <213> HUMAN <400> 873 ggggcatttc cgggtccggg ccgagcgggc gcacgcgcgg gagcgggact cggcggcatg 60 gcgggctccg gagccggtgt gcgttgctcc ctgctgcggc tgcaggagac cttgtccgct 120 gcggaccgct gcggtgctgc cctggccggt catcaactga tccgcggcct ggggcaggaa 180 tgcgtcctga gcagcagccc cgcggtgctg gcattacaga catctttagt tttttccaga 240 gatttcggtt tgcttgtatt tgtccggaag tcactcaaca gtattgaatt tcgtgaatgt 300 agagaagaaa tcctaaagtt tttatgtatt ttcttagaaa aaatgggcca gaagatcgca 360 ccttactctg ttgaaattaa gaacacttgt accagtgttt atacaaaaga tagagctgct 420 aaatgtaaaa ttccagccct ggaccttctt attaagttac ttcagacttt tagaagttct 480 agactcatgg atgaatttaa aattggagaa ttatttagta aattctatgg agaacttgca 540 ttgaaaaaaa aaataccaga tacagtttta gaaaaagtat atgagctcct aggattattg 600 ggtgaagttc atcctagtga gatgataaat aatgcagaaa acctgttccg cgcttttctg 660 ggtgaactta agacccagat gacatcagca gtaagagagc ccaaactacc tgttctggca 720 ggatgtctga aggggttgtc ctcacttctg tgcaacttca ctaagtccat ggaagaagat 780 ccccagactt caagggagat ttttaatttt gtactaaagg caattcgtcc tcagattgat 840 ctgaagagat atgctgtgcc ctcagctggc ttgcgcctat ttgccctgca tgcatctcag 900 tttagcacct gccttctgga caactacgtg tctctatttg aagtcttgtt aaagtggtgt 960 gcccacacaa atgtagaatt gaaaaaagct gcactttcag ccctggaatc ctttctgaaa 1020 caggtttcta atatggtggc gaaaaatgca gaaatgcata aaaataaact gcagtacttt 1080 atggagcagt tttatggaat catcagaaat gtggattcga acaacaagga gttatctatt 1140 gctatccgtg gatatggact ttttgcagga ccgtgcaagg ttataaacgc aaaagatgtt 1200 gacttcatgt acgttgagct cattcagcgc tgcaagcaga tgttcctcac ccagacagac 1260 actggtgacg accgtgttta tcagatgcca agcttcctcc agtctgttgc aagcgtcttg 1320 ctgtaccttg acacagttcc tgaggtgtat actccagttc tggagcacct cgtggtgatg 1380 cagatagaca gtttcccaca gtacagtcca aaaatgcagc tggtgtgttg cagagccata 1440 gtgaaggtgt tcctagcttt ggcagcaaaa gggccagttc tcaggaattg cattagtact 1500 gtggtgcatc agggtttaat cagaatatgt tctaaaccag tggtccttcc aaagggccct 1560 gagtctgaat ctgaagacca ccgtgcttca ggggaagtca gaactggcaa atggaaggtg 1620 cccacataca aagactacgt ggatctcttc agacatctcc tgagctctga ccagatgatg 1680 gattctattt tagcagatga agcatttttc tctgtgaatt cctccagtga aagtctgaat 1740 catttacttt atgatgaatt tgtaaaatcc gttttgaaga ttgttgagaa attggatctt 1800 acacttgaaa tacagactgt tggggaacaa gagaatggag atgaggcgcc tggtgtttgg 1860 atgatcccaa cttcagatcc agcggctaac ttgcatccag ctaaacctaa agatttttcg 1920 gctttcatta acctggtgga attttgcaga gagattctcc ctgagaaaca agcagaattt 1980 tttgaaccat gggtgtactc attttcatat gaattaattt tgcaatctac aaggttgccc 2040 ctcatcagtg gtttctacaa attgctttct attacagtaa gaaatgccaa gaaaataaaa 2100 tatttcgagg gagttagtcc aaagagtctg aaacactctc ctgaagaccc agaaaagtat 2160 tcttgctttg ctttatttgt gaaatttggc aaagaggtgg cagttaaaat gaagcagtac 2220 aaagatgaac ttttggcctc ttgtttgacc tttcttctgt ccttgccaca caacatcatt 2280 gaactcgatg ttagagccta cgttcctgca ctgcagatgg ctttcaaact gggcctgagc 2340 tataccccct tggcagaagt aggcctgaat gctctagaag aatggtcaat ttatattgac 2400 agacatgtaa tgcagcctta ttacaaagac attctcccct gcctggatgg atacctgaag 2460 acttcagcct tgtcagatga gaccaagaat aactgggaag tgtcagctct ttctcgggct 2520 gcccagaaag gatttaataa agtggtgtta aagcatctga agaagacaaa gaacctttca 2580 tcaaacgaag caatatcctt agaagaaata agaattagag tagtacaaat gcttggatct 2640 ctaggaggac aaataaacaa aaatcttctg acagtcacgt cctcagatga gatgatgaag 2700 agctatgtgg cctgggacag agagaagcgg ctgagctttg cagtgccctt tagagagatg 2760 aaacctgtca ttttcctgga tgtgttcctg cctcgagtca cagaattagc gctcacagcc 2820 agtgacagac aaactaaagt tgcagcctgt gaacttttac atagcatggt tatgtttatg 2880 ttgggcaaag ccacgcagat gccagaaggg ggacagggag ccccacccat gtaccagctc 2940 tataagcgga cgtttcctgt gctgcttcga cttgcgtgtg atgttgatca ggtgacaagg 3000 caactgtatg agccactagt tatgcagctg attcactggt tcactaacaa caagaaattt 3060 gaaagtcagg atactgttgc cttactagaa gctatattgg atggaattgt ggaccctgtt 3120 gacagtactt taagagattt ttgtggtcgg tgtattcgag aattccttaa atggtccatt 3180 aagcaaataa caccacagca gcaggagaag agtccagtaa acaccaaatc gcttttcaag 3240 cgactttata gccttgcgct tcaccccaat gctttcaaga ggctgggagc atcacttgcc 3300 tttaataata tctacaggga attcagggaa gaagagtctc tggtggaaca gtttgtgttt 3360 gaagccttgg tgatatacat ggagagtctg gccttagcac atgcagatga gaagtcctta 3420 ggtacaattc aacagtgttg tgatgccatt gatcacctat gccgcatcat tgaaaagaag 3480 catgtttctt taaataaagc aaagaaacga cgtttgccgc gaggatttcc accttccgca 3540 tcattgtgtt tattggatct ggtcaagtgg cttttagctc attgtgggag gccccagaca 3600 gaatgtcgac acaaatccat tgaactcttt tataaattcg ttcctttatt gccaggcaac 3660 agatccccta atttgtggct gaaagatgtt ctcaaggaag aaggtgtctc ttttctcatc 3720 aacacctttg aggggggtgg ctgtggccag ccctcgggca tcctggccca gcccaccctc 3780 ttgtaccttc gggggccatt cagcctgcag gccacgctat gctggctgga cctgctcctg 3840 gccgcgttgg agtgctacaa cacgttcatt ggcgagagaa ctgtaggagc gctccaggtc 3900 ctaggtactg aagcccagtc ttcacttttg aaagcagtgg ctttcttctt agaaagcatt 3960 gccatgcatg acattatagc agcagaaaag tgctttggca ctggggcagc aggtaacaga 4020 acaagcccac aagagggaga aaggtacaac tacagcaaat gcaccgttgt ggtccggatt 4080 atggagttta ccacgactct gctaaacacc tccccggaag gatggaagct cctgaagaag 4140 gacttgtgta atacacacct gatgagagtc ctggtgcaga cgctgtgtga gcccgcaagc 4200 ataggtttca acatcggaga cgtccaggtt atggctcatc ttcctgatgt ttgtgtgaat 4260 ctgatgaaag ctctaaagat gtccccatac aaagatatcc tagagaccca tctgagagag 4320 aaaataacag cacagagcat tgaggagctt tgtgccgtca acttgtatgg ccctgacgcg 4380 caagtggaca ggagcaggct ggctgctgtt gtgtctgcct gtaaacagct tcacagagct 4440 gggcttctgc ataatatatt accgtctcag tccacagatt tgcatcattc tgttggcaca 4500 gaacttcttt ccctggttta taaaggcatt gcccctggag atgagagaca gtgtctgcct 4560 tctctagacc tcagttgtaa gcagctggcc agcggacttc tggagttagc ctttgctttt 4620 ggaggactgt gtgagcgcct tgtgagtctt ctcctgaacc cagcggtgct gtccacggcg 4680 tccttgggca gctcacaggg cagcgtcatc cacttctccc atggggagta tttctatagc 4740 ttgttctcag aaacgatcaa cacggaatta ttgaaaaatc tggatcttgc tgtattggag 4800 ctcatgcagt cttcagtgga taataccaaa atggtgagtg ccgttttgaa cggcatgtta 4860 gaccagagct tcagggagcg agcaaaccag aaacaccaag gactgaaact tgcgactaca 4920 attctgcaac actggaagaa gtgtgattca tggtgggcca aagattcccc tctcgaaact 4980 aaaatggcag tgctggcctt actggcaaaa attttacaga ttgattcatc tgtatctttt 5040 aatacaagtc atggttcatt ccctgaagtc tttacaacat atattagtct acttgctgac 5100 acaaagctgg atctacattt aaagggccaa gctgtcactc ttcttccatt cttcaccagc 5160 ctcactggag gcagtctgga ggaacttaga cgtgttctgg agcagctcat cgttgctcac 5220 ttccccatgc agtccaggga atttcctcca ggaactccgc ggttcaataa ttatgtggac 5280 tgcatgaaaa agtttctaga tgcattggaa ttatctcaaa gccctatgtt gttggaattg 5340 atgacagaag ttctttgtcg ggaacagcag catgtcatgg aagaattatt tcaatccagt 5400 ttcaggagga ttgccagaag gggttcatgt gtcacacaag taggccttct ggaaagcgtg 5460 tatgaaatgt tcaggaagga tgacccccgc ctaagtttca cacgccagtc ctttgtggac 5520 cgctccctcc tcactctgct gtggcactgt agcctggatg ctttgagaga attcttcagc 5580 acaattgtgg tggatgccat tgatgtgttg aagtccaggt ttacaaagct aaatgaatct 5640 acctttgata ctcaaatcac caagaagatg ggctactata agattctaga cgtgatgtat 5700 tctcgccttc ccaaagatga tgttcatgct aaggaatcaa aaattaatca agttttccat 5760 ggctcgtgta ttacagaagg aaatgaactt acaaagacat tgattaaatt gtgctacgat 5820 gcatttacag agaacatggc aggagagaat cagctgctgg agaggagaag actttaccat 5880 tgtgcagcat acaactgcgc catatctgtc atctgctgtg tcttcaatga gttaaaattt 5940 taccaaggtt ttctgtttag tgaaaaacca gaaaagaact tgcttatttt tgaaaatctg 6000 atcgacctga agcgccgcta taattttcct gtagaagttg aggttcctat ggaaagaaag 6060 aaaaagtaca ttgaaattag gaaagaagcc agagaagcag caaatgggga ttcagatggt 6120 ccttcctata tgtcttccct gtcatatttg gcagacagta ccctgagtga ggaaatgagt 6180 caatttgatt tctcaaccgg agttcagagc tattcataca gctcccaaga ccctagacct 6240 gccactggtc gttttcggag acgggagcag cgggacccca cggtgcatga tgatgtgctg 6300 gagctggaga tggacgagct caatcggcat gagtgcatgg cgcccctgac ggccctggtc 6360 aagcacatgc acagaagcct gggcccgcct caaggagaag aggattcagt gccaagagat 6420 cttccttctt ggatgaaatt cctccatggc aaactgggaa atccaatagt accattaaat 6480 atccgtctct tcttagccaa gcttgttatt aatacagaag aggtctttcg cccttacgcg 6540 aagcactggc ttagcccctt gctgcagctg gctgcttctg aaaacaatgg aggagaagga 6600 attcactaca tggtggttga gatagtggcc actattcttt catggacagg cttggccact 6660 ccaacagggg tccctaaaga tgaagtgtta gcaaatcgat tgcttaattt cctaatgaaa 6720 catgtctttc atccaaaaag agctgtgttt agacacaacc ttgaaattat aaagaccctt 6780 gtcgagtgct ggaaggattg tttatccatc ccttataggt taatatttga aaagttttcc 6840 ggtaaagatc ctaattctaa agacaactca gtagggattc aattgctagg catcgtgatg 6900 gccaatgacc tgcctcccta tgacccacag tgtggcatcc agagtagcga atacttccag 6960 gctttggtga ataatatgtc ctttgtaaga tataaagaag tgtatgccgc tgcagcagaa 7020 gttctaggac ttatacttcg atatgttatg gagagaaaaa acatactgga ggagtctctg 7080 tgtgaactgg ttgcgaaaca attgaagcaa catcagaata ctatggagga caagtttatt 7140 gtgtgcttga acaaagtgac caagagcttc cctcctcttg cagacaggtt catgaatgct 7200 gtgttctttc tgctgccaaa atttcatgga gtgttgaaaa cactctgtct ggaggtggta 7260 ctttgtcgtg tggagggaat gacagagctg tacttccagt taaagagcaa ggacttcgtt 7320 caagtcatga gacatagaga tgatgaaaga caaaaagtat gtttggacat aatttataag 7380 atgatgccaa agttaaaacc agtagaactc cgagaacttc tgaaccccgt tgtggaattc 7440 gtttcccatc cttctacaac atgtagggaa caaatgtata atattctcat gtggattcat 7500 gataattaca gagatccaga aagtgagaca gataatgact cccaggaaat atttaagttg 7560 gcaaaagatg tgctgattca aggattgatc gatgagaacc ctggacttca attaattatt 7620 cgaaatttct ggagccatga aactaggtta ccttcaaata ccttggaccg gttgctggca 7680 ctaaattcct tatattctcc taagatagaa gtgcactttt taagtttagc aacaaatttt 7740 ctgctcgaaa tgaccagcat gagcccagat tatccaaacc ccatgttcga gcatcctctg 7800 tcagaatgcg aatttcagga atataccatt gattctgatt ggcgtttccg aagtactgtt 7860 ctcactccga tgtttgtgga gacccaggcc tcccagggca ctctccagac ccgtacccag 7920 gaagggtccc tctcagctcg ctggccagtg gcagggcaga taagggccac ccagcagcag 7980 catgacttca cactgacaca gactgcagat ggaagaagct catttgattg gctgaccggg 8040 agcagcactg acccgctggt cgaccacacc agtccctcat ctgactcctt gctgtttgcc 8100 cacaagagga gtgaaaggtt acagagagca cccttgaagt cagtggggcc tgattttggg 8160 aaaaaaaggc tgggccttcc aggggacgag gtggataaca aagtgaaagg tgcggccggc 8220 cggacggacc tactacgact gcgcagacgg tttatgaggg accaggagaa gctcagtttg 8280 atgtatgcca gaaaaggcgt tgctgagcaa aaacgagaga aggaaatcaa gagtgagtta 8340 aaaatgaagc aggatgccca ggtcgttctg tacagaagct accggcacgg agaccttcct 8400 gacattcaga tcaagcacag cagcctcatc accccgttac aggccgtggc ccagagggac 8460 ccaataattg caaaacagct ctttagcagc ttgttttctg gaattttgaa agagatggat 8520 aaatttaaga cactgtctga aaaaaacaac atcactcaaa agttgcttca agacttcaat 8580 cgttttctta ataccacctt ctctttcttt ccaccctttg tctcttgtat tcaggacatt 8640 agctgtcagc acgcagccct gctgagcctc gacccagcgg ctgttagcgc tggttgcctg 8700 gccagcctac agcagcccgt gggcatccgc ctgctagagg aggctctgct ccgcctgctg 8760 cctgctgagc tgcctgccaa gcgagtccgt gggaaggccc gcctccctcc tgatgtcctc 8820 agatgggtgg agcttgctaa gctgtataga tcaattggag aatacgacgt cctccgtggg 8880 atttttacca gtgagatagg aacaaagcaa atcactcaga gtgcattatt agcagaagcc 8940 agaagtgatt attctgaagc tgctaagcag tatgatgagg ctctcaataa acaagactgg 9000 gtagatggtg agcccacaga agccgagaag gatttttggg aacttgcatc ccttgactgt 9060 tacaaccacc ttgctgagtg gaaatcactt gaatactgtt ctacagccag tatagacagt 9120 gagaaccccc cagacctaaa taaaatctgg agtgaaccat tttatcagga aacatatcta 9180 ccttacatga tccgcagcaa gctgaagctg ctgctccagg gagaggctga ccagtccctg 9240 ctgacattta ttgacaaagc tatgcacggg gagctccaga aggcgattct agagcttcat 9300 tacagtcaag agctgagtct gctttacctc ctgcaagatg atgttgacag agccaaatat 9360 tacattcaaa atggcattca gagttttatg cagaattatt ctagtattga tgtcctctta 9420 caccaaagta gactcaccaa attgcagtct gtacaggctt taacagaaat tcaggagttc 9480 atcagcttta taagcaaaca aggcaattta tcatctcaag ttccccttaa gagacttctg 9540 aacacctgga caaacagata tccagatgct aaaatggacc caatgaacat ctgggatgac 9600 atcatcacaa atcgatgttt ctttctcagc aaaatagagg agaagcttac ccctcttcca 9660 gaagataata gtatgaatgt ggatcaagat ggagacccca gtgacaggat ggaagtgcaa 9720 gagcaggaag aagatatcag ctccctgatc aggagttgca agttttccat gaaaatgaag 9780 atgatagaca gtgcccggaa gcagaacaat ttctcacttg ctatgaaact actgaaggag 9840 ctgcataaag agtcaaaaac cagagacgat tggctggtga gctgggtgca gagctactgc 9900 cgcctgagcc actgccggag ccggtcccag ggctgctctg agcaggtgct cactgtgctg 9960 aaaacagtct ctttgttgga tgagaacaac gtgtcaagct acttaagcaa aaatattctg 10020 gctttccgtg accagaacat tctcttgggt acaacttaca ggatcatagc gaatgctctc 10080 agcagtgagc cagcctgcct tgctgaaatc gaggaggaca aggctagaag aatcttagag 10140 ctttctggat ccagttcaga ggattcagag aaggtgatcg cgggtctgta ccagagagca 10200 ttccagcacc tctctgaggc tgtgcaggcg gctgaggagg aggcccagcc tccctcctgg 10260 agctgtgggc ctgcagctgg ggtgattgat gcttacatga cgctggcaga tttctgtgac 10320 caacagctgc gcaaggagga agagaatgca tcagttattg attctgcaga actgcaggcg 10380 tatccagcac ttgtggtgga gaaaatgttg aaagctttaa aattaaattc caatgaagcc 10440 agattgaagt ttcctagatt acttcagatt atagaacggt atccagagga gactttgagc 10500 ctcatgacaa aagagatctc ttccgttccc tgctggcagt tcatcagctg gatcagccac 10560 atggtggcct tactggacaa agaccaagcc gttgctgttc agcactctgt ggaagaaatc 10620 actgataact acccgcaggc tattgtttat cccttcatca taagcagcga aagctattcc 10680 ttcaaggata cttctactgg tcataagaat aaggagtttg tggcaaggat taaaagtaag 10740 ttggatcaag gaggagtgat tcaagatttt attaatgcct tagatcagct ctctaatcct 10800 gaactgctct ttaaggattg gagcaatgat gtaagagctg aactagcaaa aacccctgta 10860 aataaaaaaa acattgaaaa aatgtatgaa agaatgtatg cagccttggg tgacccaaag 10920 gctccaggcc tgggggcctt tagaaggaag tttattcaga cttttggaaa agaatttgat 10980 aaacattttg ggaaaggagg ttctaaacta ctgagaatga agctcagtga cttcaacgac 11040 attaccaaca tgctactttt aaaaatgaac aaagactcaa agccccctgg gaatctgaaa 11100 gaatgttcac cctggatgag cgacttcaaa gtggagttcc tgagaaatga gctggagatt 11160 cccggtcagt atgacggtag gggaaagcca ttgccagagt accacgtgcg aatcgccggg 11220 tttgatgagc gggtgacagt catggcgtct ctgcgaaggc ccaagcgcat catcatccgt 11280 ggccatgacg agagggaaca ccctttcctg gtgaagggtg gcgaggacct gcggcaggac 11340 cagcgcgtgg agcagctctt ccaggtcatg aatgggatcc tggcccaaga ctccgcctgc 11400 agccagaggg ccctgcagct gaggacctat agcgttgtgc ccatgacctc caggttagga 11460 ttaattgagt ggcttgaaaa tactgttacc ttgaaggacc ttcttttgaa caccatgtcc 11520 caagaggaga aggcggctta cctgagtgat cccagggcac cgccgtgtga atataaagat 11580 tggctgacaa aaatgtcagg aaaacatgat gttggagctt acatgctaat gtataagggc 11640 gctaatcgta ctgaaacagt cacgtctttt agaaaacgag aaagtaaagt gcctgctgat 11700 ctcttaaagc gggccttcgt gaggatgagt acaagccctg aggctttcct ggcgctccgc 11760 tcccacttcg ccagctctca cgctctgata tgcatcagcc actggatcct cgggattgga 11820 gacagacatc tgaacaactt tatggtggcc atggagactg gcggcgtgat cgggatcgac 11880 tttgggcatg cgtttggatc cgctacacag tttctgccag tccctgagtt gatgcctttt 11940 cggctaactc gccagtttat caatctgatg ttaccaatga aagaaacggg ccttatgtac 12000 agcatcatgg tacacgcact ccgggccttc cgctcagacc ctggcctgct caccaacacc 12060 atggatgtgt ttgtcaagga gccctccttt gattggaaaa attttgaaca gaaaatgctg 12120 aaaaaaggag ggtcatggat tcaagaaata aatgttgctg aaaaaaattg gtacccccga 12180 cagaaaatat gttacgctaa gagaaagtta gcaggtgcca atccagcagt cattacttgt 12240 gatgagctac tcctgggtca tgagaaggcc cctgccttca gagactatgt ggctgtggca 12300 cgaggaagca aagatcacaa cattcgtgcc caagaaccag agagtgggct ttcagaagag 12360 actcaagtga agtgcctgat ggaccaggca acagacccca acatccttgg cagaacctgg 12420 gaaggatggg agccctggat gtgaggtctg tgggagtctg cagatagaaa gcattacatt 12480 gtttaaagaa tctactatac tttggttggc agcattccat gagctgattt tcctgaaaca 12540 ctaaagagaa atgtcttttg tgctacagtt tcgtagcatg agtttaaatc aagattatga 12600 tgagtaaatg tgtatgggtt aaatcaaaga taaggttata gtaacatcaa agattaggtg 12660 aggtttatag aaagatagat atccaggctt accaaagtat taagtcaaga atataatatg 12720 tgatcagctt tcaaagcatt tacaagtgct gcaagttagt gaaacagctg tctccgtaaa 12780 tggaggaaat gtggggaagc cttggaatgc ccttctggtt ctggcacatt ggaaagcaca 12840 ctcagaaggc ttcatcacca agattttggg agagtaaagc taagtatagt tgatgtaaca 12900 ttgtagaagc agcataggaa caataagaac aataggtaaa gctataatta tggcttatat 12960 ttagaaatga ctgcatttga tattttagga tatttttcta ggttttttcc tttcatttta 13020 ttctcttcta gttttgacat tttatgatag atttgctctc tagaaggaaa cgtctttatt 13080 taggagggca aaaattttgg tcatagcatt cacttttgct attccaatct acaactggaa 13140 gatacataaa agtgctttgc attgaatttg ggataacttc aaaaatccca tggttgttgt 13200 tagggatagt actaagcatt tcagttccag gagaataaaa gaaattccta tttgaaatga 13260 attcctcatt tggaggaaaa aaagcatgca ttctagcaca acaagatgaa attatggaat 13320 acaaaagtgg ctccttccca tgtgcagtcc ctgtcccccc ccgccagtcc tccacaccca 13380 aactgtttct gattggcttt tagctttttg ttgttttttt ttttccttct aacacttgta 13440 tttggaggct cttctgtgat tttgagaagt atactcttga gtgtttaata aagttttttt 13500 ccaaaagta 13509 <210> 874 <211> 481 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(481) <223> N=any base <400> 874 aatgctaatg ataacccact aagctgattt tgtgacccat taattgtctt gatccagttt 60 gaaaaactct gaattatagg ctgtgagcac tcgctattgt tagggttagg ataatctaat 120 aagcatgagg taatggctga tgcaaggaaa agactggtta atccagaatg gctgataatt 180 tttcaaaaag ggaaacaaag ctggcaataa agggaatggt tagcaggaaa gcaaataatt 240 gaagacagca acagatgtag gtttgttggg agcgtgaggc tccaggaata aataggtgga 300 gagggcaatg ggcatggtgg ggctctcacc cggatgggna tgatgtggct ggggcagggg 360 atgacaggaa ggcccctgtc catgagtaga ctggccatgt gcttgacatt gcgctggtgg 420 gctcgctcag ggcttggaca cctctccctt gagcagccgc cagattctag agctccagag 480 a 481 <210> 875 <211> 462 <212> DNA <213> HUMAN <400> 875 attattaaaa ataataataa atatggaaca catcataaat ttatgtgtca tccttgtgca 60 gggaccatga aaatcttctc tgcatcgttc caattttagt atatgtgctg ctgaagcaag 120 cactatacta ctaattattt tttcctctgt ttggatacat gggaagtgct gtggaaataa 180 aggattccag gagtcagaag gggctataca tccaaaaccg ttatcataat gagaagaatt 240 gacctaattc caaagttcag tactgtaatt ttacaaccac ctcagtctct acatgcacag 300 aatgggtgca ttaaagacag gtatcacagt gtcatctacc cacctccttt aaagaatcac 360 tactataggc tgggcgcagt ggcttatacc tgtaatctca gcactttggg agggcaaggt 420 gggcagatca cttgaagtca gaagttggag accagcctag cc 462 <210> 876 <211> 544 <212> DNA <213> HUMAN <400> 876 agaaaaaact ggctgcttct aagtgcgaag ccggctgggc gggctggtgc cagaaagggt 60 gtgtcttcac tgccctaaga tggcctttaa ggtatacttt tgagggcttt cttgggccac 120 tttccgtaaa cacaggatgc accgatggca actggagttg tcatccgatg gtggggagag 180 gcgtgcagat tttttttgaa gggacgagcc ctgaaggagg ataggcagac ccaccagggc 240 ctcagggtac aagaaacccg aaaaaggact ggaggctgca ggcaatacgg tggtaggaat 300 ctctgccggt ttccagcgtc gcggaagcac caaagggcgg tccctgaagg aaacgagggg 360 tcttggggct ggagagcggc gcggagcgtg gtgggaatat cgtcacaacg ccgctgtcct 420 acatttctgt agcgaagact tgattacccc tagctattac ccgtgcagga gactgggccc 480 tggaccccaa atgagccaaa gtctagttga gaaaaattta cacagaataa cctcggagtt 540 catg 544 <210> 877 <211> 462 <212> DNA <213> HUMAN <400> 877 actttagaca aaaatatttt attttttttt tgacttgtta ttttgagagt ataaaagtga 60 tcatattttc ctctcttaat gagagcttat atgtaattgc ctgctgtcag tgaatcttgg 120 gtttaaggcc cattagaaaa atagcaggct ttagtagagt ggttttttcc agtgagtact 180 tttcagtcaa caggtttatt gggaggtggc taaaatgcac atggaggtga gcccttccct 240 gccagacaag caaagaatca agctgtatat ttaaaacttg gctgttaacc caaaggattt 300 ctacaggaag tttttttctc ctttgatgtt tgtagagggg ttttttttcc cctcccgaca 360 aaatcaatac acagaaaacc caaagctctt aatttgcaaa actgaatgga tttgtgaaaa 420 tagatacctt tttggcagaa atgcaatttg gcattaatcc ct 462 <210> 878 <211> 782 <212> DNA <213> HUMAN <400> 878 tttttttttt ttcaacctga cctgaggcat caattcaggc acagtataac tctgaccagt 60 aagcggaagt aacccaaatg ctttccaggg ctgaggggac atcatgagag ttgtggtcat 120 gtacagaagc acagtcccag gggcacaggt ggtacccctg taaacaaaga atttgcaata 180 ttagggcacc tcaagcagga catccattag gctgtacagg tgaacagacc tcctaccagg 240 ggaactcctg cccaagtgtt tccagtccca tctgaaaagt tcccagagtc cttggcttcc 300 aagggactgc ctgaaggcag tgagtcccaa acagttttgc ttgttcagga tacaagttga 360 tccatctcat gagcatggat gacatttgtg ggagatcttc atggaaagca tagaagctag 420 acccactctg ttgtcagtct gaactcaaag cactcacagc acatggaaag gcagcactgg 480 gaattttcct tcagcaagag gaggcttcca gggatcaagc ctccccaggt gccaggcttt 540 aattattttc tccaatatta caaaaacagt cgtgccccgt tcagcaatca taacattgca 600 ttttttcaac catctcttac tctcagctag ggcctttctc tggaagggtt gtatgtaaga 660 ggcacaaaag cattcttgta gataaacttt tttttttttt ttttggagaa agggtcgggc 720 ctgttggccc agccagagtg gcgtgggcaa attttgggct actggcaacc cccgcccctg 780 gg 782 <210> 879 <211> 356 <212> DNA <213> HUMAN <400> 879 ggggtgagag ggaagtagaa agggcaggaa gcaggatcac caaggggcaa caaggaaatt 60 ttttgggagg atggctttct tcactatctt gattgtgata atgatttcag ctgtatacta 120 aggctcagat attatcaaat tgtaatctct aggcagttta ttatatgtca atacctcaat 180 aaatctgcct aaaatgttca aaaattactg taattacaca aaatacattt tataaaaagg 240 aagtcatgag tggagcatgg ttgagaaccc cagcatctgg tagattcaga agtggggaaa 300 agcatctctc acttccgctt tttcaggccg gcgtgctgtg caatttatcc agtggc 356 <210> 880 <211> 3410 <212> DNA <213> HUMAN <400> 880 gtaccggttc ggaattcccg ggtcgaccca cgcgtccgga aggctacaga gagagccagg 60 ttttggtgcc atgcacacag ggaaacttag agttcagaga gggggtgtga tttgcctgac 120 ctcacacagc aagttagaga cccagctcca cgactcattg tcttgctgcc cagagctgct 180 ggctcccctg tttactctga gctgatcgat caccttagca cacagctggc taggagagaa 240 ccatgcagtc acttcggcca cacctgcccg ttgacccttg ctacctcggc aggctttgat 300 cccttctgac ctggaggcca gaggctaggc tgaggtcact cagcagacat caaggacctg 360 ggcagatggg ccggctggga tggtggcgag ctgtacagat aaaaagggac atgaaaatga 420 aaagcccgag cctgagtttt catcacggtt ccactcctga gtggtcttgg gtgaatcact 480 tcatctgcca aggcctggat ttcctcatct gcaaactcag aaaactaagg ctttggccct 540 cgtcatcctg cccacccagc ggggcttccc aacccaccac acagccatgg acgggaaggt 600 ggcagtgcaa gagcgtgggc ctcctgcggt ctcctgggtc cccgaggagg gagagaagtt 660 ggaccaggaa gacgaggacc aggtgaagga tcggggccaa tggaccaaca agatggagtt 720 tgtgctgtca gtggccgggg agatcattgg gctgggcaat gtctggaggt ttccctatct 780 ctgctacaaa aacggaggtg gagccttctt catcccctac ttcatcttct tctttgtctg 840 cggcatcccg gtgttcttcc tggaggtggc gttgggccaa tacaccagcc aagggagtgt 900 cacagcctgg aggaagatct gccccctctt ccagggcatt ggtctggcat ctgtggtcat 960 cgagtcatat ttgaatgtct actacatcat catccttgcc tgggctctct tctacctgtt 1020 cagctccttc acttctgagc tgccctggac gacctgcaac aacttttgga acacagagca 1080 ttgcacggac tttctgaacc actcaggagc cggcacagtg accccatttg agaattttac 1140 ctcacctgtc atggaattct gggagagacg agttctgggc atcacctcgg gcatccatga 1200 cctgggctcc ctgcgctggg agctggccct gtgcctcctg ctcgcctggg tcatctgcta 1260 tttctgcatc tggaaggggg tcaagtccac aggcaaggtg gtttatttca cagccacgtt 1320 tccgtacctg atgcttgtca ttttgctgat cagaggtgtc acccttcccg gagcctacca 1380 gggcatcatc tactacttga agccagattt gttccgcctc aaggaccctc aggtgtggat 1440 ggatgcgggc acccagatct tcttctcctt tgccatctgc caggggtgcc tgacagccct 1500 gggcagctac aacaagtatc acaacaactg ctacaaggac tgcatcgccc tctgcttcct 1560 gaacagtgcc accagctttg tggctgggtt tgttgtcttc tccatcctgg gcttcatgtc 1620 ccaagagcaa ggggtgccca tttctgaagt ggccgagtca ggtcctgggc tggccttcat 1680 cgccttcccc aaggctgtga ctatgatgcc cttatcccag ctgtggtcct gcctgttctt 1740 tatcatgctc atattcctag ggctggacag ccagtttgtc tgtgtggagt gcctggtgac 1800 agcctccata gacatgttcc ccaggcagct ccggaagagc gggcggcgcg agctcctcat 1860 cctcaccatc gccgtcatgt gctacctgat agggcttttc ctggtcaccg agggcgggat 1920 gtacatcttc cagctgtttg actactatgc ttccagtggc atatgcctgc tgttcctgtc 1980 attgtttgaa gtggtctgca taagctgggt gtatggggcg gaccgtttct atgacaacat 2040 tgaggacatg attggctacc ggccatggcc cctggtgaag atctcctggc tcttcctgac 2100 ccctggactt tgcctggcca ctttcctctt ctccttgagc aagtacaccc ccctcaagta 2160 caacaacgtc tatgtgtacc cgccctgggg atactccatt ggctggttcc tggctctgtc 2220 ctccatggtc tgtgtcccac tcttcgtcgt catcaccctc ctgaagactc ggggtccttt 2280 caggaagcgt ctgcgtcacg tcatcacccc tgactccagt ctgccacagc ccaagcaaca 2340 tccctgcttg gatggcagtg ctggccggaa ctttgggccc tccccaacaa gggaaggact 2400 gatagccggg gagaaggaga cccatttgta gggtgtggcc agagcgaggc ggctcctaag 2460 ccgggaacct aggtcagggc caccctccat tctcagcgga cagcctctgc ctctgtctcc 2520 tgccacaatc ctgctgggaa ctctggagag ccacaggcac ccccagctgg aggccagact 2580 cctctcttgt gctagctgga gcagctcctt cccctttgct gataacacca ccactgggac 2640 gtgccatgtt gggacgccac tccctgtgga aggcaccatc gtttttataa aggggggtct 2700 ttttggaggc cgccatctga ttgcaacacc tcgagttatg aggattccac tgtggggatg 2760 cctcttgtta gagcgtactg catttgtaca cggggagagg agctataatt ggaacgcaca 2820 ctgccgtcca atgtggagag cctgatggga caataccctg ttggaagtga caactgaaca 2880 cactgtgttg gatcggaggt tccgttaggg gatccttcct taggcttaac gacagaggca 2940 agcctttgca tgccgtcagt ctggagtttc ctccgagtct ctcatggcat ctccagctcc 3000 tgccctagtt ccgcactgtt cttgcagtgt ttcatcaact cctggagcat tggaatggaa 3060 ggggcttggg agatgattcc tagacttcac aaacactcgg catgcctccc tgcactgtcc 3120 gttcctctgc ccaaggccga tattgctaac tgatcacaga ttctttccca cctcacaatc 3180 ctccgaatgt gctccaggcg acaccatttg ccatcctgct tctaacgcaa acccctgact 3240 tcatggatga ggaacctgga gaccaaagag acaaagggac tttttcaagt tcacatgggg 3300 acccccttct tgggggccag agatatgact aaaaccttat ctccttgtgc tcaggccagt 3360 gtcttcccat taaccccctg ccttagttaa caagtgtgta tggattgcca 3410 <210> 881 <211> 454 <212> DNA <213> HUMAN <400> 881 tttttttttt tttttttttg aactcgagat tatttttatt atagtcaatg tttttcacac 60 acacacacat atatatacac acacacacac atctaaaatg agtcagattc tctgattact 120 cttatgttca ttatgtaaac tccagtttag aatatttcat ctatttaatc tgcaatttct 180 agtatattgg cataggtttg ccgcctgttc cattgttagt tttggaaaac gtgtgtacga 240 tctgtagggc tgtctgctgg ctcactccca tatggaaatg catgcctgct ctttctttct 300 ctttttcatt gtagttagaa ttcatgagtg tgattcatgt tttcaagaat gagcttcact 360 ggctttgttg aattttcaag ctttggtttt tcctcatgaa caactcctct tattattgtt 420 attattccct ttcttacgcc ttcatttgga ataa 454 <210> 882 <211> 339 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(339) <223> N=any base <400> 882 tttgtattca attttattgg atataaattc cacatcagta aacctgattc tcttaaaaat 60 ctacacagaa aaaaaaaaag agagagaggt tgagttgggt agttgttggt atttttgttt 120 ttgtttcttt gcttattcag ttgaggttta ttgtaaaact tgacaccaga aaaaggaaga 180 agtggcgttt ttgtgctgtg agcgtgtgac gtgtgtcctt tccagagaaa ggacagtcat 240 ggtgcttttt tatcctctct gcccaaagaa ggaaagctct taacagccag caggaggctt 300 tgtagggacc agcgttatca ncgccagtcg cgctgacca 339 <210> 883 <211> 1013 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(1013) <223> N=any base <400> 883 tttggattat atcataagtg taataggtga cagcctgctg aaacatttta ggggcattcc 60 ttgtacaaaa cgtacacata aattaaaaaa tcaatttagc tttctacaac ggtggatgcc 120 aacccaaaca catttccagg gagaatattt cagttagatg tagatcttct tcatcttgca 180 aattgacttc tgaggtacat gacagtgaat gtcattccag ccccattcgt ctgaagaacg 240 gaaatttatt atcgcacaac gctcatcaag gttattgggt tcacctgagt gccagaatgt 300 gacaagttca ttgtatggtg tctggtcaac ccattgccaa tgtcgccgac cccctggatc 360 tgacagcccc agaaaataag aagaatttct tttcagattc tgaatgatga aatcctgttc 420 ttccctgggg gtgatcacca ccagatcagc tcacatcaca gaagaggtgc tttgactctt 480 agtccaagat gcatcccagt agaaatatag tagcaactag gactgaatga agtccagggg 540 ttgggcagca gctccaatct tctatgtact tatcttacag gacgcaggtc ggcttgagtg 600 agaccgttga actccgtaac ttggacgacc tctggacgtt ttgcatacat aaaattgtga 660 ggcactcggt cctgaggctc tcttcaggca acaatgtgtg ggcgcacaca cttggacatt 720 ctctatcagg tgggtgcgaa gcgactggta aaactttctc caaagatggt gacttgcgga 780 gttgtggttg tatgctaaac aggccaagcc tcgagagccc ttcgcgtcta ggcctgaggc 840 angtaggggc atcgcacacc aatgtcaggt cagcacgaga gtagcaactt ggaggagaag 900 ttgatacgtg ggagcacgtg actgccagcg cggtagttac gagcatatag aatgggtacg 960 ctcgaaggtt acgacggttt cgtcgcgcag gcgtgtgggt gtctgctaga gtc 1013 <210> 884 <211> 486 <212> DNA <213> HUMAN <400> 884 gagtgagcca gatgaagagg agctttattg agtgacagaa cagctctgag gaaacccaca 60 ggggggcagc tcctttctgc agccagggtg tcccaacgtc tgttcagctc ctagcagaaa 120 gggttaggca agtcgtccca acaagtgttc agctatcagt agagagggta gctcctctct 180 gcagctggtc gtcccatcat ctccctgtca tctttccatc atctctgcag ctttcagcaa 240 agagggggcc ctagagtggg ttgctcctgt ctgcaggtgg tcatcccaac atttgcccag 300 ctctggctga gcctggggct tttatgggcc tcaaagggga ggaagtgcat gctgtgccaa 360 ctggtccaag ggtggccatg ggcaggcccg aaaaaggcac cataagttcc cactccagtc 420 cacaggactg gcagcctggc ccccagcctt caagcccttc ttggcctgaa ggtggggcct 480 caccaa 486 <210> 885 <211> 448 <212> DNA <213> HUMAN <400> 885 cttttttcgc tctatgccct cctggcccct tctccacttt ccatggtccc tccaactcaa 60 agaactcaat tatctgcctg cagatttccc cttcccctcc tcgcagcctg ccctaaacac 120 accctcctcc caagcccatg cagaggcaca gaaggaaggc caagccaggg ctcggaaggg 180 ctgctgccag gcctcctcca gcctcaacta tgtgttcccc gggcttggct gcctcggccg 240 actctcttag gcccaacgat ggaaatgggg acgtttccag ggcaatgaca gttaacagct 300 aagaggagtg acaggaagga agatgtattc ttcaatcctt cagtcccaac tgccccacag 360 ggaggtgctt cagaaggccc aggcctcaga gcctcccatc tccctgaggt gccaggtgga 420 cctcccgtaa tgcagttctt agaatcag 448 <210> 886 <211> 513 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(513) <223> N=any base <400> 886 atctttttgt caatttatta ttattatggg ctcatgaatt cctattccat tcaatgtata 60 atctgttact atcatctatt ttgatggtct aatagtccca gattaccttg gaaaccatta 120 tgcaatgatt tcttagatat gacaccaaaa gcacatgcaa caaaaggaaa aatagataaa 180 ttgcatatca tcaaaattaa aaactttggg gcttcaaaga acaccaccaa gaaagtgaaa 240 ggcaacccac agaatgggaa aaaatatctg ccatatatct gctgctggtc tagtatccag 300 aatatataaa gaacacttcc aactcagtaa taaaaagaaa actcaatttt aaactgggca 360 aaagtttggg aaaatagcta ttttcccaaa gatatacaat ggccaataag cacatgaaag 420 taaaatcaac attcataacc atccaggaaa tgccaatcna aaccacaaaa tggataccag 480 ttcacaccca ctaggagaac ttttgtccag gaa 513 <210> 887 <211> 420 <212> DNA <213> HUMAN <400> 887 tggcaatgaa agaaggcaag tttattagag caacagtgta tggcaaagtg gctgctcccc 60 agagcagggt tctttcatag gcagagctgc ccagagcaca gcagcagcag cagcagcagt 120 ccttatggat tgctggctag ctatatttat acacagtctt cgttatatgc tatttaagga 180 gtaggttatt cagaattttc tagaaaaggg gtgggggagt tcctggaacc atataaggaa 240 acttctgggt tgttgccatg gcatttgtaa actgtcatgg cactggtggg actgtcttta 300 tgcttattag cagtgagggc aagagggtca cttttggttg ctatccgctg gtttcggctg 360 gtgtctttgc tgcatcctgc tttgattagt agggtcatga tcggtgctcg gaatataagt 420 <210> 888 <211> 484 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(484) <223> N=any base <400> 888 tttttttttt tttttttttt tttttttttt tttttttttt tttttttttt ttggggaggg 60 gcccacccaa tgtttattga acagcgaaaa caaaaaaaac agcccctgga gccctatatg 120 gggaaaggac cccttctgga caaaaaaaat attcggggcc catggggttt gagtctgtta 180 aaaaggaccc taaggcccat gggtggggat ctttgcgtca taaacacggg ggagcccatg 240 ggggaacccc cccttgtctg taggtttcca ggctgggccc aaaggggagg gcaaaaagtt 300 gggggtccca agggatctcc ccacaacttc ctccagggca ggatttccac ccaggcccag 360 gctgcccgtt cctttccttt tccgccagtt tgggctgggg gtgccacggg tcacacccaa 420 aggagggggg taggaggcca aggcccccan ccccccatgt ttcttccccg ccccgaaaga 480 ggaa 484 <210> 889 <211> 6817 <212> DNA <213> HUMAN <400> 889 cagctccgag gggagtcgga ccggagcaaa cagccacccc cggcttcgtc ccccacgaag 60 aggaagggca ggagccgtgc cctcgaggcc gtgcccgccc cgcccgccag cggcccccgg 120 gctcccgcca aggagtcccc acccaagagg gtgcccgatc ccagcccagt caccaagggc 180 actgcggccg agagcgggga ggaggcggcg cgggccatcc cccgcgagct cccggtcaag 240 agcagctcgc tgctgccgga gatcaagccc gagcacaaga ggggcccgct ccccaaccac 300 ttcaacggcc gggcagaggg aggtcgaagc agagagctgg gcagagcggc cggagcgcct 360 ggagcttctg acgccgacgg cttgaagccc aggaaccatt tcggcgtggg caggtcgaca 420 gtgaccacta aagtgaccct ccctgccaag cccaaacatg tggaactaaa tcttaaaacc 480 cctaagaatc ttgacagttt gggaaatgag cacaatccat ttagccagcc agttcacaaa 540 ggcaacactg ccaccaaaat ctccttattt gaaaacaaac ggacaaacag tagcccaaga 600 cacactgaca ttcgaggccc aaggaatact cctgcctcta gtaaaacgtt tgttgggagg 660 gcaaagctga atttagccaa aaaagccaaa gaaatggagc aacctgaaaa gaaagtaatg 720 ccaaacagtc cccagaatgg tgtgctggtt aaggaaactg ctatagaaac caaagttacc 780 gtctcggaag aagagattct gccagcaacc agaggaatga atggagactc ttctgagaat 840 caagctcttg gtcctcagcc taaccaagat gataaagcag atgtacaaac agatgctggc 900 tgcctttcag aaccagtggc ttctgctctg attcctgtca aggatcataa gctcttagag 960 aaggaggact cagaggctgc agacagcaaa agccttgtac ttgaaaatgt aaccgataca 1020 gcacaagaca tccccaccac tgtggatacc aaagatttac ctccaacggc catgccaaag 1080 ccacagcata cattttctga ctcacagtcc cctgctgagt catctcctgg gccttctctt 1140 tcactgtctg cacccgctcc tggggatgtt cccaaagaca catgtgttca atcacccata 1200 agcagtttcc catgcactga tctaaaagtg tcagaaaacc ataaaggatg tgttttgcct 1260 gtgtctcgtc agaacaatga gaaaatgcca cttttagaac ttggaggaga aacaacccct 1320 cctttgtcca cagagcgtag tccagaagct gtgggaagtg agtgtccatc cagagtcctc 1380 gtccaggtca ggtccttcgt gctccccgtg gagagcaccc aggatgtgag ctcccaggtc 1440 atcccagaga gctctgaagt tagagaagtg cagttgccaa cttgtcacag taatgaacct 1500 gaagtggttt ccgttgcaag ttgtgctccc ccacaagagg aagtactggg caatgaacac 1560 tctcattgca cagcagagct cgcggcaaaa tctggcccac aagtcatacc gccagcatca 1620 gagaaaactc tgcctattca ggctcaaagt cagggcagca gaacacccct gatggctgaa 1680 tccagtccca ccaactctcc cagcagcgga aatcacttag ccactcctca aaggccagat 1740 cagactgtta caaatggcca ggatagccct gccagccttt tgaacatttc tgctggtagt 1800 gatgatagtg tatttgattc ttcttctgat atggaaaaat tcactgaaat tataaaacag 1860 atggatagcg cagtttgtat gcccatgaaa agaaagaagg ccaggatgcc aaactctcct 1920 gctcctcact ttgccatgcc tcctattcac gaagaccatt tagaaaaggt gtttgatccc 1980 aaagtgttta cctttggttt ggggaagaag aaggaaagtc agccagaaat gtcaccggct 2040 ttacatttga tgcagaacct tgacacaaaa tccaaactga gacccaaacg tgcatctgct 2100 gaacagagcg tcctcttcaa gtccctgcac accaacacta atgggaacag tgagcctctg 2160 gtgatgccgg aaatcaatga caaagagaac agggacgtca caaatggtgg cattaagaga 2220 tcgagactag aaaaaagtgc acttttctca agcttgttat cttctttacc acaagacaaa 2280 atcttttctc cttctgtgac atcagtcaac actatgacca cggctttcag tacttctcag 2340 aacggttccc tatctcagtc ttcagtgtca cagcccacga ctgagggtgc cccgccctgt 2400 ggtttgaaca aagaacagtc aaatcttctg cccgacaact ccttaaaggt cttcaatttc 2460 aactcgtcaa gtacatcaca ctccagtttg aaaagtccaa gccacatgga aaaatacccg 2520 caaaaagaga aaaccaaaga agatctggat tcacgaagca acctacactt gccagaaact 2580 aaattttctg aattgtcaaa actgaagaat gatgatatgg aaaaggctaa tcatattgaa 2640 agtgttatta aatcaaactt gccaaactgt gcaaacagtg acaccgactt catgggtctt 2700 ttcaaatcaa gccggtatga cccaagcatt tctttttctg gaatgtcatt atcagacaca 2760 atgacactta gaggaagtgt ccaaaataaa ctcaatcccc gacctggaaa ggtagtgata 2820 tatagtgaac ccgacgtctc tgagaagtgc attgaagttt tcagtgacat tcaggattgc 2880 agttcttgga gcctctctcc agtgatactc ataaaagttg ttagaggatg ttggattttg 2940 tatgagcaac caaattttga agggcactcc atccccttag aagaaggaga attggaactc 3000 tctggtctct ggggtataga agacattttg gaaaggcacg aagaagcaga gtctgataag 3060 ccagtggtga ttggttccat cagacatgtg gttcaggatt acagagttag tcacattgac 3120 ttatttactg aaccagaagg gttaggaatc ctaagttcct actttgatga tactgaagaa 3180 atgcagggat ttggtgtaat gcagaagact tgttccatga aagtacattg gggcacgtgg 3240 ctgatttatg aagaacctgg atttcagggt gttcctttca tcctggaacc tggtgaatac 3300 cctgacttgt ccttctggga tacagaagca gcgtacattg gatccatgcg gcctctgaaa 3360 atgggtggcc gtaaagttga attccctaca gatccaaagg tagttgttta tgaaaagcct 3420 ttctttgaag gaaaatgtgt ggaactagaa acaggaatgt gtagttttgt catggaggga 3480 ggtgaaacag aagaggcgac tggagacgat catttgccgt ttacgtcagt ggggtctatg 3540 aaagttctaa gaggcatttg ggttgcatat gagaagcctg gatttaccgg tcatcagtat 3600 ttgctagaag aaggagaata cagggactgg aaagcctggg gaggttacaa tggagagctt 3660 cagtctttac gacctatatt aggtgatttt tcaaatgctc acatgataat gtacagtgaa 3720 aaaaactttg gatccaaagg ttccagtatt gatgtattgg gaattgttgc taatttaaag 3780 gagactggat atggagtgaa gacacagtct attaatgtac tgagtggagt atgggtagcc 3840 tatgaaaatc ctgacttcac aggagaacag tatatactgg ataaaggatt ttataccagt 3900 tttgaggact ggggaggcaa aaattataag atctcttctg ttcaacctat atgtttggat 3960 tctttcactg gcccaaggag acgaaatcag attcacttgt tttcagaacc acagtttcaa 4020 ggtcacagtc aaagttttga agaaacaaca agtcaaattg atgattcatt ttctaccaag 4080 tcttgcagag tttcaggagg cagctgggtt gtatatgatg gagaaaattt cactggtaat 4140 caatacgtgt tggaagaagg ccattatcct tgtctgtctg caatgggatg cccgcctgga 4200 gcaactttca agtctcttcg ttttatagat gttgaatttt ctgaaccaac aattattctc 4260 tttgaaagag aagacttcaa aggaaaaaag attgaactta atgcagaaac tgtcaatctc 4320 cgatccctgg gattcaacac acaaatacgc tctgttcagg ttattggtgg catatgggtt 4380 acttatgaat atggcagtta cagagggcga cagttcctat tgtcacctgc agaagtacct 4440 aattggtatg aattcagtgg ctgtcgccaa ataggttctc tacgaccttt tgttcagaag 4500 cgaatttatt tcagacttcg aaacaaagca acagggttat tcatgtcaac caatggaaac 4560 ttagaggatc tgaagcttct gaggatacag gtcatggagg atgtcggggc cgatgatcag 4620 atttggatct atcaagaagg atgtatcaaa tgcaggatag cagaagactg ctgcctgacg 4680 attgtgggca gcctggtaac atctggctcc aagctaggcc tggccctgga ccagaatgct 4740 gacagccagt tctggagctt gaagtccgat ggcaggattt acagcaagtt gaagccaaat 4800 ttagttttag acattaaagg gggcacacag tatgatcaaa atcacattat cctcaacact 4860 gtcagcaaag agaagtttac acaagtgtgg gaagccatgg tcctatatac ctgaacaaag 4920 aaggaagaag aatcttctgg aggtccttcc agccacctta tttcttaaaa aggacaatgc 4980 tgatggaaga ccagactgga aagtggatcg actcctcctt cattgattct aaattcaacc 5040 ttaaatcatg ctgccatgac tcagagaact tactcatcgt ttcaaaagac tatcatagct 5100 ttaaaccaat aatttgtcct cctttcattt cttgcctttc atttttggta gctgcttaaa 5160 caggttgcct aattagcagc ttttgggtga ttttgtaaaa tgttatatca agatttcaag 5220 actgtgtaca ttttaaatta tttccaaaga tagtgacagg agagaactgg aacaaattta 5280 ccaactttgt ggacctacaa agcccttaca ctttaaaggg taagacaaag gcttaagttt 5340 gaaaggtaga gaactgttta gcatctgaga agaaatactt tattaggcct gtaattttgg 5400 ttcttggcct taaacacttt ctggaacctt taaatatgct gcatagcaca atgggaaagc 5460 cttaggtatt cacacattta aggaactcta aacaaaatac tattttcctt tagttcatat 5520 taaaaattaa tacattttaa aaatttaatg tcaaagtctg gtaacatttg ttagtaggat 5580 ttgagttatt attttttgag acaggatctc aggctggagt gcagtggcac aatcacggct 5640 cactgcagcc tctacctccc caggctcagg tgatcctccc acctcagcct cccaagtagc 5700 tgggactata ggcacacatc accaagccca gccaaatttt gttttttttt tgtagagatg 5760 gggtttcatc acgttgccca ggctgatctc gaacctctgg gctcaagcaa ttcactcgcc 5820 tcggcctccc aaaatgctgg gattacaggc ctgagccact gcgcccagcc aggatttgaa 5880 ttattttaac tcatccatgg gctgccctag aatgtcacaa atgagggttg tttaatgcct 5940 ttcttatagc tgctactgga acactattat gacctaattt atgagccatc cttactcatc 6000 tacaagtgct gaagcaatgt tacatacttt tttgctaaac tcagattttt tagcctaatt 6060 tcttgtcctc ctatccacct gcatccacac atggcctgca tggggctgcc ttccctgcag 6120 tgttctgcag ccatgcttca gggtatagct gttggtggac agcctcaggt cttgggggca 6180 ctatagccac taaacgaggt gtgaaaggct caagaggatg accagcaatt aattatcccc 6240 agaaagtgaa ggaaaagaga cctttaggga tgttgctggt caagtcttga tttgaccgga 6300 gtcaaatcaa tcttcaagca atcttggaat cctcaactgc agtaagcatt tcaaaatgca 6360 aacaaactgc ttaacaactg acaagacacc agcccatatg ctgctcttcc aacagtgggt 6420 tctagctttg aacaaaagtg ctaaacattt ccttgaatat attcttcctc tttttgtcct 6480 catcactcaa tactggtgct cttgtcacag gtagaacagc ttgtttcttt tccatctatt 6540 caagtgtgtt tctaattcta aaatgctgat cttctctgga gtctatggta ggcaattatg 6600 gtcactggaa tagtttgtct tgttttaaaa tattattggt gcatgtacaa cagcatccaa 6660 catatctgtc ttgttcctag atatatagct ctgattttag gccttttgtg cataccatta 6720 caatatggtg gggtaagaca ttctacagta gcctgtgctg aactgatctc ttaaataaac 6780 ttgcttctgg ttaactaaaa aaaaaaaaaa aaaaaaa 6817 <210> 890 <211> 291 <212> DNA <213> HUMAN <400> 890 gagaagacga cagaagggag ttccaaatag gcagtttgtg actgatgatg agcatgttga 60 tgataaagtc tcctttatat aacagccggc agacgacttg gtcacgccca cacattttaa 120 attcacataa aggtaaatat atggtcaggc gtggtggccc acacctgtag tctcagcacc 180 ttgggaggcg aaggcgggtg gatcatttga ggtcaggagt tcaagaccag tctggccaac 240 atggtgaaac tctatctcta ccaaaataca aaaaaaaaaa agtcgtatcg a 291 <210> 891 <211> 450 <212> DNA <213> HUMAN <400> 891 agttcaaata tataccttta tttgaacaag agaatggagg actaggataa aacctacctg 60 ggtgaggcag ccaaatccat ggtgccttgg tgggggcaga cagttcctgg gggataacac 120 tgaatcccac aaaggcagaa acaatccaca cacaggccac tgggatcagc acctgagggg 180 cgagactgag aaaagaactc ctcccccaaa accttctgag ccagccttgc aggggtagac 240 agaagccaaa aggtagggga tggagtgagc actccaggcc agcccttctg acctctactg 300 ccctgcccag acccacacat accgaaagga gccggaagac agggagagga gtgtgagttg 360 atgacgttga agctcgcctc caggggcaca catgaaactg gcaggagccc aggtgctgag 420 aacagaccac catgagcagg ataaccctag 450 <210> 892 <211> 401 <212> DNA <213> HUMAN <400> 892 ttttaaaatg ttttattttt atttcaccta atatgtacac atagttatat aattttgctt 60 agtgaaaagt tcatgtttta ggttccaaga acttggccaa acttgaacgc tggagagaag 120 cgaaattcac tccctagctc tggaaagggg aatttggtag aagacggatc tcatccttcc 180 aatttcttcc cctcaggtag ttttctgtaa ataattttat gaaaagtata gcaggattct 240 ctgttccagt ggttatagac aatgggattg acaatcaaat ttgcatgtga caagagaatg 300 gtcatcttcc ttgcccactt gggcttatct ttagcctgag ctagctgaaa aagagtgaca 360 cagtccatgg tgcgcactgg tagcgagcac agagcaaaca t 401 <210> 893 <211> 3176 <212> DNA <213> HUMAN <400> 893 tgataaccca aggtattcac agcaagatac agtgagtctt aaagttaagc accgtgcaat 60 tagctttgct tccttgggtt tttgaaacat gcatctgtat aaacctgcct gtgcagacat 120 cccgagcccc aagctgggtc tgccaaaatc cagtgaatcg gctctaaaat gtagatggca 180 cctagcagtg accaagactc agcctcaggc ggcctgcaaa cctgtgaggc ccagtggagc 240 agccgaacag aaatatgtgg aaaagtttct acgtgttcat ggaatttcgt tgcaggaaac 300 caccagagca gagacgggca tggcatacag gaatcttgga aaatcaggac tcagagtttc 360 ttgcttgggt cttggaacat gggtgacatt tggaggtcaa atttcagatg aggttgctga 420 acggctgatg accatcgcct atgaaagtgg tgttaacctc tttgatactg ccgaagtcta 480 tgctgctgga aaggctgaag tgattctggg gagcatcatc aagaagaaag gctggaggag 540 gtccagtctg gtcataacaa ccaaactcta ctggggtgga aaagctgaaa cagaaagagg 600 gctgtcaaga aagcatatta ttgaaggatt gaagggctcc ctccagaggc tgcagctcga 660 gtatgtggat gtggtctttg caaatcgacc ggacagtaac actcccatgg aagaaattgt 720 ccgagccatg acacatgtga taaaccaagg catggcgatg tactggggca cctcgagatg 780 gagtgctatg gagatcatgg aagcctattc tgtagcaaga cagttcaata tgatcccacc 840 ggtctgtgaa caagctgagt accatctttt ccagagagag aaagtggagg tccagctgcc 900 agagctctac cacaaaatag gtgttggcgc aatgacatgg tctccacttg cctgtggaat 960 catctcagga aaatacggaa acggggtgcc tgaaagttcc agggcttcac tgaagtgcta 1020 ccagtggttg aaagaaagaa ttgtaagtga agaagggaga aaacagcaaa acaagctaaa 1080 agacctttcc ccaattgcgg agcgtctggg atgcacacta cctcagctag ctgttgcgtg 1140 gtgcctgaga aatgaaggtg tgagttctgt gctcctggga tcatccactc ctgaacaact 1200 cattgaaaac cttggtgcca ttcaggttct cccaaagatg acatcacatg tggtaaatga 1260 gattgataac atactgcgca acaagcccta cagcaagaag gactatagat cataaggcaa 1320 tgcatgaacc acagaagctg catggttaaa atagcggcct gtgcccagta cagaaaggtg 1380 ttactaacca gtcttttgaa tcacttagca gcttgctcgt caacctctag tgtccctccc 1440 tggattcttt gaggtgtctg ctgtcgctac cactgtgcac atctgaaaac tcacaaccaa 1500 gaaaatccat tctattttct tatcttggac tggagtcacc tattcttgca ttgctgtata 1560 cacctcatgc ttatgcaatg ggaagaatat gggggccagg gggtgtggta ctaccttcag 1620 gcatttggta actcaaagaa ggctgtacag atatattttt tcaaaaagaa caaaatccac 1680 agatgcaatg tgagttgcgt aagaaacaga gtagatagac taaattcagt gaaggaaagg 1740 aattgagaga tttttcttag taaatagatt attgttaagt aaatagttat taaaaatata 1800 tctcactgca aaaaaaaaaa aagcagtatc ttcactcaaa agtcttgctt ggaagaataa 1860 gcagaaagaa ttttatatat tttttttcta ttttcacatt catactaaca agttttgttc 1920 catttgttat tcaataaaac aaaaatttct aggtatttgc tttattacct ttcaaatatt 1980 tactgttgct tggccccaag aatggccttg tacaacttat ccagaatgtc tattaggatt 2040 ctaatgttat gtccacttac aagtagagac agtaaaagga tgaataccca atctttagtg 2100 acaatgcagc tgatttatga aagagagggc tacactgcta tggaaactta gcttcaaaga 2160 aaatgcaatg tatctgcaat taggtgttca ttttttacta cattttatta aaacctgctt 2220 tatactttca actgcttgta ggcacaactt ctgcaagttt aaatatttga gctttacaaa 2280 taaacataca catgctcagt ttttttaagt aaacctgtaa aatacccagg aaggcaaatg 2340 ttcattgttt aattagcact gggattttat aatataatgt ttggtatttt tgaggcattg 2400 ttaacatgaa agtcaaccac tggctttgtg aaaaatgcta tgtcactatt cagaatatgc 2460 tgggtaaatt aacttgccta gtgaaaagca aaatgttaaa gaaagaactt ctggttctat 2520 aatcatatta tatgcactaa actatatgca tgaaagttct ttgcatggat taatggggct 2580 tacccttgtt gcactcgaaa tctgaggtgt atctagccct gccactattg gctacttacc 2640 ctcattaata tcccacttga gaaaaattgt gagactatac tgtgtcaata tctgtaaaaa 2700 gagagaaaac atgttttttt ttttttgaag ggggtggtgt gggagtggcc ctttaactcc 2760 tatttggcta tctgaggatg tacaaaattc tcatttaatt ttctggtcag caagttcccc 2820 acacagaaat cactctgagg tttacagaag aactgtaata ttattttaaa atgcgatttt 2880 ctgtcattag ttctagatat gtacttcatg gttaaattct aaatctgaaa atgctagtgg 2940 gagatatcaa gaaattttct ttttgattac tagtacctgt attctaacag agagtttgaa 3000 ttttttgccc gtgttatcag aatgatggaa attgatcatt ttcagttgtt cattgtgtat 3060 tcaatccagc tgaactgctg tatgtataga ggagcttgag gtgctgtcta atgggaaatg 3120 tgatttgatt gatttatttg cttagagtaa taaaagcatt ttgtgcattc aatctt 3176 <210> 894 <211> 979 <212> DNA <213> HUMAN <400> 894 atggctctgc agatccctgg aggcttttgg gcagcagctg tgaccgtgat gctggtgatg 60 ctgagcaccc cagtggctga ggccagagac tttcccaagg atttcttggt ccagtttaag 120 ggcatgtgct acttcaccaa cgggacagag cgcgtgcgcg gtgtggccag atacatctat 180 aaccgcgagg agtacgggcg cttcgacagc gacgttgggg agttccaggc ggtgaccgag 240 ctggggcgga gcatcgagga ctggaacaac tataaggact tcttggagca ggagcgggcc 300 gcggtggaca aggtgtgcag acacaactac gaggcggagc tgcgcacgac cttgcagcgg 360 caagtggagc ccacagtgac catctcccca tccaggacag aggccctcaa ccaccacaac 420 ctgctggtct gctcagtgac agatttctat ccagcccaga tcaaagtccg gtggtttcgg 480 aatgaccagg aggagacagc cggtgttgtg tccacctccc tcattaggaa tggtgactgg 540 accttccaga ttctggtgat gctggaaata actccccagc gtggagacat ctacacctgc 600 caagtggagc accccagcct ccagagcccc atcaccgtgg agtggcgggc tcagtctgaa 660 tctgcccaga gcaagatgct gagtggcatt ggaggcttcg tgctggggct gatcttcctc 720 gggctgggcc ttatcatccg tcacaggggt cagaaaggac ctcgagggcc tccaccagca 780 ggtcaccttc tgtgatcccc atcccaaggc actggtggtg actctgcttc ctgcactgac 840 ccagagcctc tgcctgtgca ctgcaagctg tgtctactca ggccccaagg ggactctctg 900 tttccattct ccccccacag acctgtcaag agaagcatga caaacaaaat catttaccga 960 ctttagtgct tttttccat 979 <210> 895 <211> 458 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(458) <223> N=any base <400> 895 caatagttcc tttccttatt tattagattc cagatacatg ggaccaggat ggaagcatcc 60 tagggcattt gatttacatg ggggtttctg ggagaacata tacagaggca gaaagacata 120 caagtaggtg atgctgcaat ggggaactgc cattttaaaa aatatataca tcttaagaag 180 ccattccagc catattatca ttattagaaa ataaaacaat ctttccacat agtgcttttc 240 tttggtgctg ttccgtgagc atggactctg gacccttcag tcttcttgtc acaagctggt 300 caccctcccc tgccacttcc atctgcacag agggagggca gagtctatgg ggaaaggagg 360 ccccccccac cgacacaggt gggtngcagg ttccagctcc tctaaggcgc tgccatnggc 420 cttcccgact ctggctggag tcttgagagc ctcttact 458 <210> 896 <211> 556 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(556) <223> N=any base <400> 896 tttttgtctt gcctgttatt tttattattt gacattcttt aattttgaaa agacacactg 60 gacttgatta agatctggct cttcattgtc tccagtcaaa tgtcctgtgg cgactctctg 120 tggtactgac ccttcacatc ttggtttgat atggcttact ttgtgcaaag agagggtaca 180 gtggagggag tgtatggcgg tggactccca ggtgcaggct gcataaactt tggtcaagtc 240 tgaagcttct acatcttcat tctgtggctc tcttaaggcc atcaggcaag cttctgtgca 300 gattgccttg atgtcagcac caaagaggtc atctttagtc attatcaagt cgttcaggtt 360 tacatcatcg gccagtgtca tcatgcttgt atgcatctga aagatgctct tcttagtatg 420 ttcattacgg aggggaatgc cgatcttcct gtcagtgcag gctcgcctgc taagggctgn 480 atacaaaatt ctgtttggtt gccgcatgat aactttacat gtnctctaga tcaaatccat 540 caactgttcg cagttc 556 <210> 897 <211> 716 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(716) <223> N=any base <400> 897 tttttttttc caaattatta aattttttta attaaaaaat tttttaaaat tatatttgca 60 tatatgaagg taagtaagac actggacaaa ttatagagtc tcaggcttat gtggaattat 120 gactgctctc aacaattact gaaatcccct ttcaaagaaa atcttcacat aaacctatgt 180 ttgactatgt aatagaatga agacagccac agatctggca ttctcaaaac atcacacaag 240 tactgcatgt aatgctgcaa aataactgtt ttcctctaaa atttcactaa acaacctcag 300 gcagtacaat aaaacaaaac attaagacct cccagtggtc atcctaagaa ttagacagat 360 ttctttgatt ttttcttctc tgcttcttcc ttttcctttt ctatttcagt tacatataat 420 tcaacttctt ttgcactaaa catcttcaaa ggttgatttc ttcttattat agcaagttca 480 atgttttttc caccagactg gacaacttct agcaaagctt ttattgctaa cttgatagct 540 tcactgtcac ttgctatggc atcttctgtg taattctttt ctagaaattc tcgaacagtt 600 ttagcacttc ggcctattgc atttgccttc caagcatgat aagtaccaaa aggatctgtc 660 tgatacaatc ttggagatnc attattattc aaaccctcca attaaggcgg aatacc 716 <210> 898 <211> 439 <212> DNA <213> HUMAN <400> 898 tatttgcatt attttttact gttgtcttgt tcttttttat gttttgcatc ctgaatatat 60 ttgctccaca gttggttgac cctacgtaat tccatggatg caggacccac aaatgtggat 120 ggccgaccgc acttagagaa tgctcacctg tctgcagcca agggctggaa tcacacatct 180 ggctgactca ctgaaccaca ggtgtagctc tcagagcctc cgggttggac cgaaagaaca 240 cagcgtggag taggctccac ggactacctc atgggaccac tcctcaggga aagcctctgg 300 aaaatatcgc gccccccaag aagggaaaag gaggagtgca ggagggtggc gcacccacaa 360 aggacccaac gccgggaaga ggcagaggat gctgggaaga gagaagcctc cttgccctga 420 cacagatatt tcttcctct 439 <210> 899 <211> 327 <212> DNA <213> HUMAN <400> 899 taaaatttat actatcaata attgagttta tttcaattaa taatgttaac aatgacacat 60 ttaacattat gttagagctc aatttgtata tattaacatg tatttttaaa taatttacgt 120 atttatcgtc gaatcatgta ttttttttaa agggggatgc tcaactctct caggcaaaaa 180 tgagcacctt tccgaacacc gtggggagag gcagggatgc aggcagacat atcctaaact 240 caccctcccg gcagcatcaa agtagccttc ggcagggatt tgttataatc agataaggat 300 tcgggaaggc cctttgagcc atgacgc 327 <210> 900 <211> 450 <212> DNA <213> HUMAN <220> <221> misc_feature <222> (1)..(450) <223> N=any base <400> 900 ggcaatagaa cctagaagtc agggaagctc atcccccaag gctcaggaaa gctcccaggn 60 aantggaatc ttatctgcat gtccctactt gcactcagca gagggccgca gaaggatcct 120 gttcagggct ttaaggaact aaagcattgg aaggcatccc atttctacgg gagattggaa 180 tagagccctg gctgttctgg ccagtccctg tctcagatgt tgcacttcca gcacattcta 240 cagttattct agagagctac aagcaagaaa gaggggagtc tgtgttggta caaggccacc 300 tggggagctg tccctcagag ctatcccagt actcaggaga agttacaaat gtggataagt 360 ccagagtttg aatcaagata gacctccaag ataatgtctt tttgtgagga tttgaagnta 420 gtcttgaaan caaattagtt ctttttaaaa 450

Claims (24)

  1. FTI 존재하에서 분별적으로 조절되는 유전자의 발현을 분석함으로써 환자가 FTI 치료에 반응할 것인지를 결정하는 방법.
  2. 제1항에 있어서, 상기 분별적 조절은 1.5 배이상인 것을 특징으로 하는 방법.
  3. 제1항에 있어서, 상기 분별적 조절은 1.7 배이상인 것을 특징으로 하는 방법.
  4. 제1항에 있어서, 상기 분석은 2이상의 유전자의 발현을 분석하는 것을 특징으로 하는 방법.
  5. 제1항에 있어서, 상기 유전자는 표 1-3의 하나이상의 핵산 서열과 상관되어 있는 것을 특징으로 하는 방법.
  6. 제1항에 있어서, 환자의 치료를 모니터링하기 위하여 사용되는 것을 특징으로 하는 방법.
  7. 제5항에 있어서, 상기 FTI는 (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)인 것을 특징으로 하는 방법.
  8. 제1항에 있어서, 상기 분석은 표 1-3의 핵산 서열과 상관된 유전자 군의 발현을 분석하는 것이고, 상기 FTI는 (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)인 것을 특징으로 하는 방법.
  9. a) 환자의 유전자 발현 프로필을 분석하여 상기 환자가 FTI 치료에 반응할 것인지를 결정하는 단계; 및
    b) 상기 분석 결과가 상기 환자가 반응할 것으로 나타나면, 상기 환자를 상기 FTI로 치료하는 단계를 포함하는 환자를 치료하는 방법.
  10. 제9항에 있어서, 상기 분석은 2이상의 유전자의 발현을 분석하는 것을 특징으로 하는 방법.
  11. 제9항에 있어서, 상기 FTI는 퀴놀린 또는 퀴놀린 유도체로 이루어지는 군으로부터 선택되는 것을 특징으로 하는 방법.
  12. 제11항에 있어서, 상기 FTI는
    7-(3-클로로페닐)-9-[(4-클로로페닐)-1H-이미다졸-1-일메틸]-2,3-디히드로- 1H,5H-벤조[ij]퀴놀리진-5-온,
    7-(3-클로로페닐)-9-[(4-클로로페닐)-1H-이미다졸-1-일메틸]-1,2-디히드로- 4H-피롤로[3,2,1-ij]퀴놀린-4-온,
    8-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일),메틸]-6-(3-클로로페닐)-1,2-디히드로-4H-피롤로[3,2,1-ij]퀴놀린-4-온,
    8-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-6-(3-클로로페닐)-2,3-디히드로-1H,5H-벤조[ij]퀴놀리진-5-온, 및
    (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)으로 이루어지는 군으로부터 선택되는 것을 특징으로 하는 방법.
  13. 제12항에 있어서, 상기 FTI는 (B)-6-[아미노(4-클로로페닐)(1-메틸-1H-이미다졸-5-일)메틸]-4-(3-클로로페닐)-1-메틸-2(1H)-퀴놀리논)인 것을 특징으로 하는 방법.
  14. 제10항에 있어서, 상기 유전자는 표 1-3의 하나이상의 핵산 서열과 상관되어 있는 것을 특징으로 하는 방법.
  15. 제9항에 있어서, 상기 치료는 FTI와 다른 치료용 조성물의 투여를 포함하는 것을 특징으로 하는 방법.
  16. 제15항에 있어서, 상기 다른 치료용 조성물은 MAPK/ERK 신호전달 경로, TGFβ, WNT 또는 세포자가사 경로를 조절하는 것을 특징으로 하는 방법.
  17. 제16항에 있어서, 상기 다른 치료용 조성물은 티로신 키나제 저해제, MEK 키나제 저해제, PI3 키나제 저해제, MAP 키나제 저해제, 세포자가사 조절인자, 및 그의 조합물로 이루어지는 군으로부터 선택되는 것을 특징으로 하는 방법.
  18. FTI 반응성을 지시하는 환자 유전자 발현 프로필이 결정되는 매체를 포함하는 FTI 환자 치료의 효율을 검사하는 물품.
  19. 제18항에 있어서, 상기 유전자 발현 프로필은 표 1-3의 2이상의 핵산 서열과 상관된 유전자 군으로부터 얻어지는 것을 특징으로 하는 물품.
  20. 제19항에 있어서, 상기 핵산 서열은 표 3에 나타낸 것임을 특징으로하는 물품.
  21. 제18항에 있어서, 매체에 고정된 유전자 발현 프로필의 표현물을 포함하는것을 특징으로 하는 물품.
  22. 제18항에 있어서, 상기 매체는 컴퓨터 판독가능한 것을 특징으로 하는 물품.
  23. FTI 치료에 대한 반응성을 결정하기 위한 유전자 발현 프로필을 얻기 위한 물품을 포함하는 키트.
  24. 제23항에 있어서, 지침서를 더 포함하는 것을 특징으로 하는 키트.
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