KR20210129508A - Dressig agent for cavity wound treatment - Google Patents

Abstract

The present invention relates to a dressing material for the treatment of pupil wounds.
The dressing material for the treatment of pupil wounds of the present invention has a lattice structure smaller than the diameter of the polyurethane granular balls and the polyurethane granular balls and consists of a mesh surrounding the polyurethane granular balls, so that various depths and shapes of the pupil wounds Accordingly, the polyurethane granular ball can be easily filled and replaced, and it is easy to remove after wound treatment, thereby enabling easy pupil inflow of the polyurethane granular ball and increasing the pupil filling rate, It is effective for excellent healing of pupil wounds by increasing the exudate absorption capacity by increasing the contact area with the wound site.

Description

Dressing material for the treatment of pupil wounds {DRESSIG AGENT FOR CAVITY WOUND TREATMENT}

The present invention relates to a dressing material for the treatment of a hole wound, cavity wound, and more particularly, a polyurethane granular ball and a polyurethane granular ball having a lattice structure smaller than the diameter of the polyurethane granular ball It relates to a dressing material for the treatment of pupil wounds that can be easily filled, replaced, and removed from the polyurethane granular ball according to various depths and shapes of the pupil wound, consisting of a mesh surrounding the pupil.

A typical example of a wound where the pupil is formed is a pressure sore. A pressure sore is any lesion caused by continuous or repeated compression or abrasion of the tissue between the bone protrusion and the epidermis. refers to ulcers.

In general, the deep layer is wider than the shallow layer of the ulcer, and it is characterized by the creation of a pouch-shaped pupil wound. According to one study, the risk of pressure sores in elderly people who lie in bed for a long time is about 38%, and the risk of bedsores increases as the length of bed sickness increases. When the bone is exposed and an infection occurs through this area, various complications such as cellulitis, osteomyelitis, and sepsis occur, which threatens even life.

In particular, the most serious complication of pressure sores is sepsis, which is spread throughout the body by bacteria infiltrating the site of pressure sores, and when the pressure sores cause sepsis, the mortality rate reaches 60%.

In addition, the wound in which the pupil is formed is not limited to a specific part of the body, such as a car accident trauma, diabetic ulcer such as foot ulcer and necrosis, or venous ulcer, and pupil filling is essential for the treatment of the wound in which the pupil is formed.

It is important to treat a wound with a pupil formed so that secretions do not accumulate at the wound site. If secretions such as blood and pustules continue to accumulate at the wound site, an environment is created for bacteria to inhabit, causing further infection, and causing erosion of the tissue adjacent to the wound, which can make the wound larger.

Nevertheless, a suitable environment for healing a wound where the pupil is formed is preferably a state in which the exudate is completely removed and adequate moisture is maintained rather than a dry state.

Therefore, wet dressing methods that prevent the body fluids secreted from the wound from being dehydrated or dried are currently confirmed to facilitate wound healing. and moisture permeability, preventing drying of the wound surface, and preventing maceration (erosion) of surrounding normal skin.

In addition, it should have functions such as exchange of gas and prevention of intrusion of bacteria from the outside, and should not adhere to the wound surface and damage new tissues during exchange. In addition, if the wound healing state can be easily observed, non-irritating, easy to use, and economical, an ideal dressing material is required. Research to develop a dressing material that satisfies all of these ideal conditions is steadily progressing.

The dressing materials that have been used relatively recently are as follows. In the early 1970s, "OpSite™" was introduced as a semi-permeable, transparent film, which promotes wound healing by facilitating dissolution of necrotic tissue and formation of granulation tissue by keeping the wound moist. However, it is pointed out that the excessive amount of exudate accumulates around the wound, causing the surrounding skin to become crushed, and the problem that the exudate leaks out and must be arbitrarily discharged has been pointed out.

Also, in 1982, a product called "DuoDERM™" was introduced in the United States, which is a hydrocolloid dressing that reacts with exudate when attached to a wound and provides a moist environment in the form of a gel to promote wound epithelialization. However, since gases and water vapor such as oxygen and carbon dioxide do not pass, there is still a disadvantage of excessive exudate accumulation, there is another problem that the gel may remain on the wound surface when changing the dressing.

Recently, a dressing material using a polymer has been released, and a foam manufacturing method of forming an open cell by foaming a synthetic polymer such as polyurethane has been proposed.

Polyurethane foam dressing products are composed of foamed urethane or polymers in the form of open cells that contain exudates. It has high absorbency and retention for the price, so it has the advantages of high exudate absorption and maintaining a moist environment conducive to wound healing.

In addition, it enables wound repair through closure and wetting, blocks the wound site from water and bacteria, and in the case of thick foam, it has a cushioning effect and helps to distribute pressure, so it is applied to various types of wounds. It is also diverse. Moisture absorption capacity depends on the size and number of open cells, and the outer surface of the polyurethane foam is covered with a thin film, which controls moisture permeability to maintain a wet environment and prevents adsorption to wounds. Depending on the amount of exudate, various thickness products can be selected.

Patent Document 1 is an invention related to a polyurethane foam dressing material that protects wounds such as wounds and burns and helps wound healing, comprising: a waterproof polyurethane film layer; a foam layer made of polyurethane foam and formed under the polyurethane film layer; It provides a hydrophilic polyurethane foam dressing material comprising a mesh film layer formed under the foam layer. In the present invention, including the mesh film layer formed under the foam layer, the mechanical properties of the foam dressing material after absorbing exudate are reduced, and it is reported that the phenomenon of sticking the foam dressing material to the wound surface can be improved.

In addition, Patent Document 2 is another type of polyurethane foam dressing-related invention, which is a microporous polyurethane foam layer containing a silver-activated carbon complex obtained by impregnating activated carbon in a silver nitrate solution and then heat-treating it under an inert gas as an antibacterial active ingredient. class; a polyurethane film layer attached to the upper surface of the foam layer and being moisture-permeable and waterproof; It provides an antibacterial polyurethane foam dressing material comprising a perforated polyurethane film layer attached to the lower surface of the foam layer and coming into contact with the wound surface.

However, polyurethane foam dressing products have excellent absorbency and retention for their price, so they can be effective for wounds with a relatively large amount of exudate, such as bedsores, but are mainly limited to a form that covers the affected area flat.

Therefore, since it is a method of cutting and using an appropriate size according to the size of the wound, it is impossible to fill the entire pupil for the treatment of a wound in which the pupil is formed.

Conventionally, except for dressing products in the form of gauze, sponge, and some fibers for the treatment of wounds in which pupils are formed, such as bedsores, a vacuum assisted closure (VAC) treatment method using negative pressure has been practiced.

For gauze dressings, the wet gauze must be changed frequently and continuously to moisten the base of the wound and maintain re-wetting. In this process, a sheet of gauze has to be unwrapped by hand, and it is soaked in a liquid such as physiological saline or povidone solution, squeezed out, and then applied to the wound. In addition, if the gauze remaining deep in the pupil cannot be removed, another inflammation may be induced, and tissue regeneration may be delayed due to adhesion to the gauze in the process of healing the wounded area.

In the case of a sponge, an additional cost is incurred because it is accompanied by an essential disinfection process before application to the wound.

In addition, the fiber-type product group fully achieves the purpose of wet dressing by taking advantage of absorbency due to the characteristics of the material. In addition, when the pupil is large, there is a problem in that the filling is incomplete only with a fiber product, so that gauze or the like must be used as an auxiliary.

Currently, in the case of VAC (Vacuum Assisted Closure) using negative pressure, which is the most excellent treatment method in terms of healing results and filling of wounds with pupil formation, it accompanies the machine body that creates negative pressure, and a wide tape is used to maintain the negative pressure. In some cases, treatment itself is refused due to problems such as the need to attach a

Accordingly, the present inventors, as a result of efforts to solve the problems of the prior art, provide a dressing material wrapped with a mesh of a size that the polyurethane granular ball and the polyurethane granular ball will not come out for the treatment of wounds in which the pupil is formed, and the dressing The present invention was completed by confirming that it is easy to fill and replace the ash pupil wound, and it is easy to remove after the wound is treated.

Korean Patent No. 1202875 (Registered on November 13, 2012) Republic of Korea Patent Publication No. 2020-0013449 (published on Feb. 7, 2020)

An object of the present invention is to provide a dressing material for the treatment of pupil wounds.

Another object of the present invention is to provide an individually packaged dressing product in which the above-mentioned dressing material for the treatment of the pupil wound is packaged according to the size of the pupil wound.

In order to achieve the above object, the present invention provides a dressing material for pupil wound treatment consisting of a polyurethane granular ball and a mesh having a lattice structure smaller than the diameter of the polyurethane granular ball and enclosing the polyurethane granular ball. .

In the dressing material for the treatment of pupil wounds of the present invention, the polyurethane granular ball consists of particles having a diameter of 5 to 15 mm.

In addition, in the dressing material for the treatment of pupil wounds of the present invention, the polyurethane granular ball may contain two or more kinds of particles having different diameters mixed, and the two or more kinds of particles having different diameters are agents having a diameter of 5 to 15 mm. It may be included in the form of a mixture between one particle and the second particles of 1 to 4 mm smaller than the first particle diameter.

In the dressing material for treating a pupil wound of the present invention, the mesh is made of a non-degradable material, and an antiseptic agent or a wound healing agent may be further included in the polyurethane granular ball.

Furthermore, the present invention provides an individually packaged dressing product in which the above-mentioned dressing material for treating a pupil wound is packaged for each size of the pupil wound, and a protective film is included.

The dressing material for the treatment of pupil wounds of the present invention has a lattice structure smaller than the diameter of the polyurethane granular ball and the polyurethane granular ball and consists of a mesh surrounding the polyurethane granular ball, so that a conventional flat sheet form is applied. It is effective for difficult concave dented pupil wounds.

In addition, due to the use of the dressing material for the treatment of pupil wounds of the present invention, it is possible to easily fill, replace, and remove the polyurethane granular balls according to various depths and shapes of pupil wounds, thereby reducing concerns about further induced inflammation. minimized, and will be beneficial for tissue regeneration at the wound site.

The dressing material for the treatment of pupil wounds of the present invention is manufactured by adjusting the diameter of the polyurethane granular ball, so that a granular ball corresponding to the pupil wound size can be applied, and easy pupil inflow of the polyurethane granular ball is induced. And, it can increase the pupil filling rate, increasing the contact area with the wound site, increasing the exudate absorption capacity, and maximizing the healing effect of the pupil wound.

1 is a schematic diagram of a dressing material for treating a pupil wound according to a first embodiment of the present invention applied to the pupil wound;
Figure 2 is a schematic diagram applied to the pupil wound dressing material for the pupil wound treatment of the second embodiment of the present invention,
3 is a schematic diagram showing the process in which the dressing material for the treatment of the pupil wound of the present invention is introduced into the pupil wound;
Figure 4 is a schematic view of the application of the protective film to the dressing material for the treatment of pupil wounds of the present invention.

Hereinafter, the present invention will be described in detail.

The present invention provides a dressing material for treating a pupil wound consisting of a polyurethane granular ball and a mesh having a lattice structure smaller than the diameter of the polyurethane granular ball and surrounding the polyurethane granular ball.

1) Polyurethane granular ball

Polyurethane provides a sufficient wet dressing environment due to its excellent absorbency and retention for its price, and can be applied to various types of wounds. In particular, since the exudate does not remain on the wound due to its high liquid absorption capacity, it is effective in treating pupil wounds with a relatively large amount of exudate, such as bedsores.

In particular, it helps to distribute pressure due to the cushioning effect inherent in the material, so it is also useful for treating pressure-induced lesions such as bedsores.

Polyurethane may use dense polyurethane and foamed polyurethane, but more preferably, foamed polyurethane is used. Polyurethane foam is a conventionally known synthetic method of preparing a polyurethane prepolymer by adding isocyanate to a polyol and diol mixed solution and reacting it by a known method, and mixing water, a crosslinking agent and a foaming agent in the foamed form. Manufactured or commercially available products may be used. In the dressing material for treating a pupil wound of the present invention, it is provided in the form of a polyurethane granular ball, thereby increasing the contact area with the exudate and effectively absorbing a large amount of exudate.

In addition, by being provided in the form of a polyurethane granular ball, it can be easily filled in a pupil wound of a concave shape such as a pressure sore, and the polyurethane granular ball can be easily filled, replaced and Since it can be removed, it is possible to minimize concerns about further induced inflammation and to expect an effective wound healing effect.

Therefore, in the dressing material for the treatment of pupil wounds of the present invention, the polyurethane granular ball can be manufactured by adjusting the diameter according to the depth and shape of the pupil wound.

1 is a schematic diagram of the dressing material for treating a pupil wound according to a first embodiment of the present invention applied to the pupil wound, and a polyurethane granular ball made of single-sized particles (1) and a lattice smaller than the diameter of the polyurethane granular ball; It has a structure and provides a dressing material (4') for treating a pupil wound consisting of a mesh (3) surrounding the polyurethane granular ball.

A feature of the first embodiment of the present invention is that the polyurethane granular balls are composed of single-sized particles having a diameter of 5 to 15 mm, more preferably 5 to 10 mm. At this time, if the granules are smaller than 5 mm, the size of the eye of the mesh surrounding the polyurethane granular ball should be small. Since it serves to provide an environment, it is not desirable. On the other hand, if the polyurethane granular ball exceeds 15 mm in diameter, the contact surface with the wound is excessively reduced, resulting in a problem in the wound healing effect.

In the first embodiment, the polyurethane granular ball composed of particles of a single size has a diameter determined according to various depths and shapes of the pupil wound within the range of 5 to 15 mm, but preferably a polyurethane granular ball consisting of 5 mm. it was used However, it will of course be understood that changes may be made in consideration of the manufacturing capability of the company or the environment in actual application in the actual production situation.

At this time, the first embodiment including a polyurethane granular ball made of a single-sized particle (1) can control the voids between the particles, thereby providing moisture permeability and breathability, which will help wound healing.

Figure 2 is a schematic diagram of the dressing material for the treatment of pupil wounds of the second embodiment of the present invention applied to the pupil wound, the first particles (1) of the polyurethane granular balls having different diameters and the second particles of the polyurethane granular balls ( 2) provides a dressing material (4) for the treatment of pupil wounds consisting of a mixed granular ball and a mesh (3) surrounding the polyurethane granular ball.

A characteristic of the first embodiment of the present invention is to use a polyurethane granular ball in which two or more kinds of particles having different diameters are mixed, and more preferably, two or more kinds of particles having different diameters for the purpose of controlling voids between the particles. is made of a mixture form between the first particles having a diameter of 5 to 15 mm and the second particles of particles 1 to 4 mm smaller than the first particle diameter.

At this time, the second particle may be used in a mixture of one or two or more types of various sizes corresponding to the diameter, and it is smaller than the eye of the mesh so that particle dropout should not occur, and the voids between the first particles are arranged too closely. The particle size is not preferred.

Figure 3 is a schematic view showing the process of the pupil wound treatment dressing material of the present invention is introduced into the pupil wound, the pupil wound treatment dressing material of the present invention is wrapped around the polyurethane granular ball with a mesh so as not to fall off, the shape is It can be applied flexibly without being in the form of a film or solidification, so if the dressing material of the first and second embodiments is injected into the pupil wound, the pupil filling is possible regardless of the depth or shape of the wound due to the flexibility of the dressing material of the present invention. Easy.

Moreover, in the case of the dressing material for treating a pupil wound according to the second embodiment, when the pupil entrance is narrow, the small particle diameter is injected first and the space will be filled with its own volume when it is filled in the upper body.

2) netting

In the dressing material for the treatment of pupil wounds of the present invention, the mesh (3) has a lattice structure smaller than the diameter of the polyurethane granular ball, prevents the polyurethane granular ball from leaking out and facilitates the polyurethane granular ball In order to wrap it tightly, it should be a material that has adequate tensile strength that is not easily torn, does not easily decompose even when it comes into contact with a large amount of exudate, has almost no tissue immune response such as foreign body reaction, and does not act as a factor that interferes with wound healing. .

The mesh 3 used in the present invention is preferably a non-degradable material. As a specific example, natural fibers such as cotton and acetate, and synthetic materials such as silicone and nylon may be used. However, in the case of biodegradable materials such as Vicryl, since there is a risk of inflammatory reaction and bacterial infection in vivo, it is not preferable for wound treatment of ulcers caused by tissue necrosis, such as bedsores.

In the dressing material for the treatment of pupil wounds of the present invention, by using the mesh 3, the dressing material of the present invention can be stably seated on the pupil wound through clustering of polyurethane granular balls, and is collected from the wound as well as filling. Make it easy to replace and remove at one time.

In general, dressing material replacement is performed at intervals of 1 to 2 days, and when the amount of exudate is large, it is desirable for pupil wound management to replace it as often as possible. can do.

From the above, the dressing material (4, 4') for the treatment of pupil wounds of the present invention can be customized to various depths and shapes of wounds, and in the case of a severe stage of pressure sores, extensive tissue necrosis of muscles, bones, supporting tissues, etc. As the ulceration occurs, the deeper layer is more widely distributed than the shallow layer of the ulcer, giving it the shape of a pocket, and the surface is uneven. It can be usefully applied to various wounds, such as wound size, pupil depth and shape, which vary depending on the stage and aspect of the process.

In addition, the dressing material for the treatment of pupil wounds of the present invention can be easily filled in pupil wounds of various depths and shapes.

The filling effect of the dressing material for the treatment of pupil wounds of the present invention can shorten the time required for dressing and the problem of having to manually untie a sheet of gauze in the case of a gauze dressing.

In addition, the dressing material for the treatment of pupil wounds of the present invention is easy to replace and remove after filling, so it is possible to solve the inflammation problem that occurs when the gauze remaining deep in the pupil after dressing cannot be removed, and in the process of healing the wound site Adhesion problems with tissue regeneration can be minimized.

Furthermore, the dressing material for the treatment of pupil wounds of the present invention can increase the ability to treat inflammatory wounds by further containing an antiseptic or wound healing agent in the polyurethane granular ball in order to manage the infection of the wound.

At this time, the disinfectant or wound healing agent may include antibacterial and disinfecting substances such as silver ions, povidone iodine, betadine, chlorhexidine, and polyhexamethylene biguanide (PHMB), It can be added when manufacturing a polyurethane granular ball by selecting alone or two or more types.

Therefore, the wound site to which the dressing material of the present invention can be applied is concave with pressure sores, traffic accident trauma, foot ulcers, diabetic ulcers such as necrosis, venous ulcers, ulcers accompanied by exudate, ulcers where granulation tissue grows, ulcers requiring filling, etc. It is useful for the treatment of pitted pupil wounds.

Furthermore, the present invention provides an individually packaged dressing product in which the above-mentioned dressing material for treating a pupil wound is packaged for each size of the pupil wound, and a protective film is included.

Specifically, the polyurethane granular ball wrapped by the mesh in the dressing material for the treatment of pupil wounds of the present invention may be manufactured as a dressing product such as 5cc, 20cc type depending on the loading volume.

When selecting the volume, it is not necessary to fit the size of the pupil wound, but if the total volume of the granular ball cluster is smaller than the volume of the pupil wound, the pupil wound cannot be completely filled, and it has a slight cushioning effect to help distribute the pressure It is preferable to select a granular ball cluster with a volume slightly larger than the volume of the pupil in order to take advantage of the material properties of the polyurethane that gives it.

These examples are for explaining the present invention in more detail, and the technical scope of the present invention is not limited to these examples.

Figure 4 is a schematic view of the application of the protective film to the dressing material for the treatment of pupil wounds of the present invention, it may further include a protective film (5) for covering the pupil wound.

The protective film included in the individually wrapped dressing product may be provided in a size configured to be 1 to 2 cm larger than the individually wrapped dressing, and may be provided as a full paper so that it can be cut and used in the entire area by the size of the dressing.

The protective film 5 serves to block the entrance to the pupil wound area, thereby protecting the wound area from further harm by blocking external infection, alleviating pain, and removing psychological stress, to help you recover quickly.

At this time, the protective film can be stably attached to the wound site because it has excellent elasticity and adhesion as well as a waterproof function. As a material for the protective film, a nonwoven fabric and polyurethane material with excellent ventilation so as not to scorch the wound are also preferable.

In the above, the present invention has been described in detail only with respect to the described embodiments, but it is obvious to those skilled in the art that various changes and modifications are possible within the scope of the technical spirit of the present invention, and it is natural that such variations and modifications belong to the appended claims.

1: First particle of polyurethane granular ball
2: Second particle of polyurethane granular ball
3: mesh
4, 4': dressing material for the treatment of pupil wounds
5: protective film
6: The skin side of the pupil wound
7: Muscular side of the pupil wound
8: Skeletal side of the pupil wound

Claims (7)

polyurethane granulated balls and
A dressing material for the treatment of pupil wounds having a lattice structure smaller than the diameter of the polyurethane granular ball and comprising a mesh surrounding the polyurethane granular ball. The dressing material for treating a pupil wound according to claim 1, wherein the polyurethane granular ball is made of particles having a diameter of 5 to 15 mm. The dressing material for treating pupil wounds according to claim 1, wherein the polyurethane granular ball is a mixture of two or more types of particles having different diameters. The pupil according to claim 3, wherein the two or more types of particles having different diameters are a mixture between a first particle having a diameter of 5 to 15 mm and a second particle having a particle size of 1 to 4 mm smaller than the first particle diameter. Dressing material for wound healing. [Claim 2] The dressing material for treating a pupil wound according to claim 1, wherein the mesh is made of a non-degradable material. The dressing material for treating a pupil wound according to claim 1, wherein an antiseptic agent or a wound healing agent is further included in the polyurethane granular ball. Claims 1 to 6, wherein the dressing material for the pupil wound treatment of any one of claims is packaged for each size of the pupil wound, individually packaged dressing products containing a protective film.

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