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KR950700287A - 스테로이드 5알파-리덕타아제 억제제로서의 인돌 유도체(Indole Derivatives as Steroid 5 Alpha-Reductase Inhibitors) - Google Patents

스테로이드 5알파-리덕타아제 억제제로서의 인돌 유도체(Indole Derivatives as Steroid 5 Alpha-Reductase Inhibitors)

Info

Publication number
KR950700287A
KR950700287A KR1019940703018A KR19940703018A KR950700287A KR 950700287 A KR950700287 A KR 950700287A KR 1019940703018 A KR1019940703018 A KR 1019940703018A KR 19940703018 A KR19940703018 A KR 19940703018A KR 950700287 A KR950700287 A KR 950700287A
Authority
KR
South Korea
Prior art keywords
pct
steroid
alpha
reductase inhibitors
indole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019940703018A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR950700287A publication Critical patent/KR950700287A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019940703018A 1992-02-28 1994-08-27 스테로이드 5알파-리덕타아제 억제제로서의 인돌 유도체(Indole Derivatives as Steroid 5 Alpha-Reductase Inhibitors) Ceased KR950700287A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929204365A GB9204365D0 (en) 1992-02-28 1992-02-28 Indoles
PCT/EP1993/000380 WO1993017014A1 (en) 1992-02-28 1993-02-16 Indole derivatives as steroid 5 alpha-reductase inhibitors

Publications (1)

Publication Number Publication Date
KR950700287A true KR950700287A (ko) 1995-01-16

Family

ID=10711259

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940703018A Ceased KR950700287A (ko) 1992-02-28 1994-08-27 스테로이드 5알파-리덕타아제 억제제로서의 인돌 유도체(Indole Derivatives as Steroid 5 Alpha-Reductase Inhibitors)

Country Status (24)

Country Link
US (1) US5767139A (ko)
EP (1) EP0628040B1 (ko)
JP (1) JP2540016B2 (ko)
KR (1) KR950700287A (ko)
CN (1) CN1079465A (ko)
AT (1) ATE164376T1 (ko)
AU (1) AU3497793A (ko)
BR (1) BR9305991A (ko)
CA (1) CA2117610C (ko)
CZ (1) CZ207794A3 (ko)
DE (1) DE69317651T2 (ko)
DK (1) DK0628040T3 (ko)
ES (1) ES2115053T3 (ko)
FI (2) FI943931A7 (ko)
GB (1) GB9204365D0 (ko)
HR (1) HRP930227A2 (ko)
HU (1) HUT71126A (ko)
IL (1) IL104816A0 (ko)
MX (1) MX9301112A (ko)
NO (1) NO943187L (ko)
RU (1) RU94042391A (ko)
SK (1) SK100894A3 (ko)
WO (1) WO1993017014A1 (ko)
ZA (1) ZA931383B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL109728A0 (en) * 1993-05-28 1994-08-26 Pfizer Res & Dev Indoles
ES2099007B1 (es) * 1993-07-16 1997-12-01 Pfizer Res & Dev Derivados de indol.
GB9317096D0 (en) 1993-08-17 1993-09-29 Pfizer Ltd Indoles
GB9403516D0 (en) * 1994-02-24 1994-04-13 Pfizer Ltd Indoles
GB9409583D0 (en) * 1994-05-13 1994-07-06 Pfizer Ltd Indoles
EP0820441B1 (en) * 1995-04-10 2002-06-26 Fujisawa Pharmaceutical Co., Ltd. INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS
ES2263283T3 (es) 1998-08-03 2006-12-01 ELI LILLY & COMPANY Inhibidores de spla2 indol.
FR2796279B1 (fr) 1999-07-16 2001-09-21 Oreal Utilisation de l'acide 4,6-dimethoxy-indole 2-carboxylique ou de ses derives pour le traitement de la seborrhee
FR2796274B1 (fr) * 1999-07-16 2001-09-21 Oreal Utilisation de l'acide 4,6-dimethoxy-indole 2-carboxylique ou de ses derives pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
HRP20050396A2 (en) * 2002-11-07 2005-06-30 Akzo Nobel N.V. Indoles useful in the treatment of androgen-receptor related diseases
UA79504C2 (en) * 2002-11-07 2007-06-25 Organon Nv Indols for treating diseases associated with androgen receptors
TW200602317A (en) 2004-04-23 2006-01-16 Akzo Nobel Nv Novel androgens
GB201102913D0 (en) 2011-02-18 2011-04-06 Univ Birmingham Novel therapeutic

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3557142A (en) * 1968-02-20 1971-01-19 Sterling Drug Inc 4,5,6,7-tetrahydro-indole-lower-alkanoic acids and esters
PH23498A (en) * 1984-08-06 1989-08-16 Sterling Drug Inc 3-carbonyl-1-aminoalkyl-1h-indoles,composition and use thereof
CA2036307C (en) * 1990-03-08 2002-07-09 Susan Jean Ward 3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions and method
GB9011335D0 (en) * 1990-05-21 1990-07-11 Fujisawa Pharmaceutical Co Indolebutyric acid derivatives and process for preparation thereof
IL109728A0 (en) * 1993-05-28 1994-08-26 Pfizer Res & Dev Indoles

Also Published As

Publication number Publication date
CA2117610C (en) 2000-07-18
NO943187L (no) 1994-09-13
FI943931A0 (fi) 1994-08-26
ES2115053T3 (es) 1998-06-16
ATE164376T1 (de) 1998-04-15
WO1993017014A1 (en) 1993-09-02
RU94042391A (ru) 1996-08-10
US5767139A (en) 1998-06-16
CA2117610A1 (en) 1993-09-02
CN1079465A (zh) 1993-12-15
JPH07500347A (ja) 1995-01-12
BR9305991A (pt) 1997-10-21
IL104816A0 (en) 1993-06-10
NO943187D0 (no) 1994-08-29
AU3497793A (en) 1993-09-13
MX9301112A (es) 1994-07-29
HU9402466D0 (en) 1994-10-28
ZA931383B (en) 1994-08-26
EP0628040B1 (en) 1998-03-25
DK0628040T3 (da) 1998-04-27
DE69317651D1 (en) 1998-04-30
CZ207794A3 (en) 1995-01-18
GB9204365D0 (en) 1992-04-08
SK100894A3 (en) 1995-04-12
HRP930227A2 (en) 1996-10-31
DE69317651T2 (de) 1998-07-09
EP0628040A1 (en) 1994-12-14
JP2540016B2 (ja) 1996-10-02
HUT71126A (en) 1995-11-28
FI943931A7 (fi) 1994-08-26
FI20001771A7 (fi) 2000-08-09

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Legal Events

Date Code Title Description
A201 Request for examination
PA0105 International application

Patent event date: 19940827

Patent event code: PA01051R01D

Comment text: International Patent Application

PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19940827

Comment text: Request for Examination of Application

PG1501 Laying open of application
E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19970826

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 19971125

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 19970826

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I