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SE8902257D0 - A process for the preparation of drug particles - Google Patents

A process for the preparation of drug particles

Info

Publication number
SE8902257D0
SE8902257D0 SE8902257A SE8902257A SE8902257D0 SE 8902257 D0 SE8902257 D0 SE 8902257D0 SE 8902257 A SE8902257 A SE 8902257A SE 8902257 A SE8902257 A SE 8902257A SE 8902257 D0 SE8902257 D0 SE 8902257D0
Authority
SE
Sweden
Prior art keywords
drug
preparation
aqueous phase
particles
emulsifying
Prior art date
Application number
SE8902257A
Other languages
English (en)
Other versions
SE464743B (sv
SE8902257L (sv
Inventor
B Sjoestroem
Original Assignee
Ytkemiska Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ytkemiska Inst filed Critical Ytkemiska Inst
Priority to SE8902257A priority Critical patent/SE464743B/sv
Publication of SE8902257D0 publication Critical patent/SE8902257D0/sv
Priority to AU59375/90A priority patent/AU5937590A/en
Priority to PCT/SE1990/000426 priority patent/WO1990015593A1/en
Publication of SE8902257L publication Critical patent/SE8902257L/sv
Publication of SE464743B publication Critical patent/SE464743B/sv

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE8902257A 1989-06-21 1989-06-21 Foerfarande foer framstaellning av laekemedelspartiklar SE464743B (sv)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SE8902257A SE464743B (sv) 1989-06-21 1989-06-21 Foerfarande foer framstaellning av laekemedelspartiklar
AU59375/90A AU5937590A (en) 1989-06-21 1990-06-15 A process for the preparation of drug particles
PCT/SE1990/000426 WO1990015593A1 (en) 1989-06-21 1990-06-15 A process for the preparation of drug particles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8902257A SE464743B (sv) 1989-06-21 1989-06-21 Foerfarande foer framstaellning av laekemedelspartiklar

Publications (3)

Publication Number Publication Date
SE8902257D0 true SE8902257D0 (sv) 1989-06-21
SE8902257L SE8902257L (sv) 1990-12-22
SE464743B SE464743B (sv) 1991-06-10

Family

ID=20376358

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8902257A SE464743B (sv) 1989-06-21 1989-06-21 Foerfarande foer framstaellning av laekemedelspartiklar

Country Status (3)

Country Link
AU (1) AU5937590A (sv)
SE (1) SE464743B (sv)
WO (1) WO1990015593A1 (sv)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
AU642066B2 (en) * 1991-01-25 1993-10-07 Nanosystems L.L.C. X-ray contrast compositions useful in medical imaging
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
DE69309056T2 (de) * 1992-06-10 1997-09-18 Nanosystems L.L.C., Collegeville, Pa. Oberflaechenmodifizierte nsaid nanopartikeln
US5346702A (en) * 1992-12-04 1994-09-13 Sterling Winthrop Inc. Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization
US5352459A (en) * 1992-12-16 1994-10-04 Sterling Winthrop Inc. Use of purified surface modifiers to prevent particle aggregation during sterilization
DE4308121A1 (de) * 1993-03-15 1994-09-22 Rhone Poulenc Rorer Gmbh Wäßriges Liposomensystem sowie Verfahren zur Herstellung eines derartigen Liposomensystems
JPH09511520A (ja) * 1994-04-11 1997-11-18 マリンクロッド・メディカル・インコーポレイテッド カルシウム/オキシアニオン含有粒子の微流体化
FR2721510B1 (fr) * 1994-06-22 1996-07-26 Rhone Poulenc Rorer Sa Nanoparticules filtrables dans des conditions stériles.
SE9403846D0 (sv) * 1994-11-09 1994-11-09 Univ Ohio State Res Found Small particle formation
GB0008411D0 (en) * 2000-04-05 2000-05-24 Vectura Ltd Pharmaceutical preparations and their manufacture
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US6884436B2 (en) 2000-12-22 2005-04-26 Baxter International Inc. Method for preparing submicron particle suspensions
US6951656B2 (en) 2000-12-22 2005-10-04 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US6977085B2 (en) 2000-12-22 2005-12-20 Baxter International Inc. Method for preparing submicron suspensions with polymorph control
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US7037528B2 (en) 2000-12-22 2006-05-02 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US7193084B2 (en) 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
WO2003013683A1 (en) 2001-08-08 2003-02-20 Brown University Research Foundation Methods for micronization of hydrophobic drugs
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
BR0212833A (pt) 2001-09-26 2004-10-13 Baxter Int Preparação de nanopartìculas de tamanho submìcron através de dispersão e de remoção de solvente ou de fase lìquida
US7112340B2 (en) 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
WO2003059319A1 (en) * 2002-01-14 2003-07-24 Dow Global Technologies Inc. Drug nanoparticles from template emulsions
ATE343376T1 (de) * 2002-03-20 2006-11-15 Elan Pharma Int Ltd Nanopartikelzusammensetzungen von angiogeneseinhibitoren
US20080220075A1 (en) * 2002-03-20 2008-09-11 Elan Pharma International Ltd. Nanoparticulate compositions of angiogenesis inhibitors
EP1800666A1 (en) * 2002-03-20 2007-06-27 Elan Pharma International Limited Nanoparticulate compositions of angiogenesis inhibitors
WO2003103632A1 (en) * 2002-06-10 2003-12-18 Elan Pharma International, Ltd. Nanoparticulate polycosanol formulations and novel polycosanol combinations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2348334C2 (de) * 1973-09-26 1982-11-11 Boehringer Mannheim Gmbh, 6800 Mannheim Neue Zubereitungsform des N-4-[2-(5-Chlor-2-methoxybenzamido)äthyl]- phenyl-sulfonyl-N'-cyclohexylharnstoffs
DE2817453A1 (de) * 1978-04-21 1979-10-31 Rohner Ag Verfahren zur herstellung von in waessrigen medien dispergierbaren, konzentrierten praeparaten in form von rieselfaehigen staubarmen pulvern oder granulaten ausgehend von in wasser schwerloeslichen bis unloeslichen wirksubstanzen
US4826689A (en) * 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
CA1282405C (en) * 1984-05-21 1991-04-02 Michael R. Violante Method for making uniformly sized particles from water-insoluble organic compounds

Also Published As

Publication number Publication date
SE464743B (sv) 1991-06-10
AU5937590A (en) 1991-01-08
WO1990015593A1 (en) 1990-12-27
SE8902257L (sv) 1990-12-22

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