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SE9901379D0 - Receptor structures - Google Patents

Receptor structures

Info

Publication number
SE9901379D0
SE9901379D0 SE9901379A SE9901379A SE9901379D0 SE 9901379 D0 SE9901379 D0 SE 9901379D0 SE 9901379 A SE9901379 A SE 9901379A SE 9901379 A SE9901379 A SE 9901379A SE 9901379 D0 SE9901379 D0 SE 9901379D0
Authority
SE
Sweden
Prior art keywords
domain
amino acid
acid residues
substitution
receptor structures
Prior art date
Application number
SE9901379A
Other languages
English (en)
Inventor
Charlotta Ljungqvist
Karin Nord
Per-Aake Nygren
Mathias Uhlen
Original Assignee
Pharmacia & Upjohn Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab
Priority to SE9901379A priority Critical patent/SE9901379D0/sv
Publication of SE9901379D0 publication Critical patent/SE9901379D0/sv
Priority to US09/549,441 priority patent/US6602977B1/en
Priority to EP00921293A priority patent/EP1179014B1/en
Priority to PCT/SE2000/000732 priority patent/WO2000063243A1/en
Priority to DK00921293T priority patent/DK1179014T3/da
Priority to AU41624/00A priority patent/AU4162400A/en
Priority to DE60041052T priority patent/DE60041052D1/de
Priority to AT00921293T priority patent/ATE417058T1/de
Priority to JP2000612330A priority patent/JP4578690B2/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SE9901379A 1999-04-19 1999-04-19 Receptor structures SE9901379D0 (sv)

Priority Applications (9)

Application Number Priority Date Filing Date Title
SE9901379A SE9901379D0 (sv) 1999-04-19 1999-04-19 Receptor structures
US09/549,441 US6602977B1 (en) 1999-04-19 2000-04-14 Receptor structures
EP00921293A EP1179014B1 (en) 1999-04-19 2000-04-17 Derivatives of the z domain from staphylococcal protein a (spa) interacting with at least one domain of human factor viii
PCT/SE2000/000732 WO2000063243A1 (en) 1999-04-19 2000-04-17 Derivatives of the b or z domain from staphylococcal protein a (spa) interacting with at least one domain of human factor viii
DK00921293T DK1179014T3 (da) 1999-04-19 2000-04-17 Derivater af Z-domænet fra staphylococcalt protein A (SPA), som interagerer med mindst ét domæne fra human faktor VIII
AU41624/00A AU4162400A (en) 1999-04-19 2000-04-17 Derivatives of the b or z domain from staphylococcal protein a (spa) interactingwith at least one domain of human factor viii
DE60041052T DE60041052D1 (de) 1999-04-19 2000-04-17 Derivate der z-domäne des proteins a von staphylococcus (spa), welche mit mindestens einer domäne des humanen faktors viii interagieren
AT00921293T ATE417058T1 (de) 1999-04-19 2000-04-17 Derivate der z-domäne des proteins a von staphylococcus (spa), welche mit mindestens einer domäne des humanen faktors viii interagieren
JP2000612330A JP4578690B2 (ja) 1999-04-19 2000-04-17 ヒト第ｖｉｉｉ因子の少なくとも１ドメインと相互作用するスタフィロコッカスタンパク質ａ（ｓｐａ）由来のｂまたはｚドメインの誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9901379A SE9901379D0 (sv) 1999-04-19 1999-04-19 Receptor structures

Publications (1)

Publication Number Publication Date
SE9901379D0 true SE9901379D0 (sv) 1999-04-19

Family

ID=20415254

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9901379A SE9901379D0 (sv) 1999-04-19 1999-04-19 Receptor structures

Country Status (8)

Country Link
EP (1) EP1179014B1 (sv)
JP (1) JP4578690B2 (sv)
AT (1) ATE417058T1 (sv)
AU (1) AU4162400A (sv)
DE (1) DE60041052D1 (sv)
DK (1) DK1179014T3 (sv)
SE (1) SE9901379D0 (sv)
WO (1) WO2000063243A1 (sv)

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JP2005504261A (ja) * 2001-01-12 2005-02-10 アフィボディ・アーベー 検出方法
JP4554356B2 (ja) * 2002-04-29 2010-09-29 アフィボディ・アーベー サンドイッチアッセイおよびキット
EP2135879A3 (en) * 2002-06-28 2010-06-23 Domantis Limited Ligand
US9321832B2 (en) 2002-06-28 2016-04-26 Domantis Limited Ligand
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
SE0301936D0 (sv) * 2003-06-30 2003-06-30 Affibody Ab New polypeptide
JP4871126B2 (ja) * 2003-07-04 2012-02-08 アフィボディ・アーベー Ｈｅｒ２に対する結合親和性を有するポリペプチド
SE0301987D0 (sv) * 2003-07-04 2003-07-04 Affibody Ab New polypeptide
GB0524788D0 (en) * 2005-12-05 2006-01-11 Affibody Ab Polypeptides
EP2099932A4 (en) 2006-12-06 2009-11-18 Repligen Corp NUCLEIC ACIDS ENCODING THE RECOMBINANT PROTEIN A
US8198043B2 (en) 2006-12-08 2012-06-12 General Electric Company Two helix binders
US7989216B2 (en) 2006-12-08 2011-08-02 General Electric Company Two helix binders
US7977118B2 (en) 2006-12-08 2011-07-12 General Electric Company Two helix binders
US7981691B2 (en) 2006-12-08 2011-07-19 General Electric Company Two helix binders
WO2008110348A1 (en) 2007-03-12 2008-09-18 Esbatech Ag Sequence based engineering and optimization of single chain antibodies
SI2158315T1 (sl) 2007-06-25 2016-05-31 Esbatech, An Alcon Biomedical Research Unit Llc Postopki za spreminjanje protiteles in spremenjena protitelesa z izboljšanimi funkcionalnimi lastnostmi
ES2532725T3 (es) 2007-06-25 2015-03-31 Esbatech, An Alcon Biomedical Research Unit Llc Modificación por ingeniería genética basada en secuencia y optimización de anticuerpos de cadena sencilla
US8426557B2 (en) 2007-08-03 2013-04-23 Affibody Ab IGF-1R binding polypeptides and their use
GB2453589A (en) 2007-10-12 2009-04-15 King S College London Protease inhibition
BRPI0914666A2 (pt) 2008-06-25 2015-10-20 Esbatech Alcon Biomed Res Unit otimização da solubilidade de ligantes imunológicos
US8592555B2 (en) 2008-08-11 2013-11-26 Emd Millipore Corporation Immunoglobulin-binding proteins with improved specificity
KR101671537B1 (ko) 2008-08-11 2016-11-01 넥타르 테라퓨틱스 다분지형 중합체 알카노에이트 컨쥬게이트
WO2010021720A1 (en) 2008-08-19 2010-02-25 Nektar Therapeutics Conjugates of small-interfering nucleic acids
SG195555A1 (en) 2008-12-24 2013-12-30 Emd Millipore Corp Caustic stable chromatography ligands
AU2011222991B2 (en) 2010-03-05 2015-07-16 Boehringer Ingelheim International Gmbh Selective enrichment of antibodies
SI2591006T1 (sl) 2010-07-09 2019-10-30 Bioverativ Therapeutics Inc Enoverižne molekule, ki jih lahko obdelujemo in polipeptidi izdelani z njihovo uporabo
WO2012088422A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
WO2012088445A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
WO2012166555A1 (en) 2011-05-27 2012-12-06 Nektar Therapeutics Water - soluble polymer - linked binding moiety and drug compounds
SG186552A1 (en) 2011-06-08 2013-01-30 Emd Millipore Corp Chromatography matrices including novel staphylococcus aureus protein a based ligands
JP6094486B2 (ja) 2011-08-11 2017-03-15 小野薬品工業株式会社 Ｐｄ−１アゴニストからなる自己免疫疾患治療剤
PT2802606T (pt) 2012-01-10 2018-07-13 Biogen Ma Inc Melhoramento do transporte de moléculas terapêuticas através da barreira hematoencefálica
WO2013175276A1 (en) 2012-05-23 2013-11-28 Argen-X B.V Il-6 binding molecules
EP2940197B1 (en) 2012-12-27 2019-02-27 National Institute of Advanced Industrial Science and Technology Molecule library constructed on the basis of backbone structure of microprotein
CN105377880B (zh) * 2013-07-10 2020-08-07 通用电气医疗集团生物工艺研发股份公司 突变的免疫球蛋白结合多肽
CN105473606A (zh) * 2013-08-28 2016-04-06 阿菲博迪公司 具有突变的支架的结合多肽
KR20220030956A (ko) 2019-07-05 2022-03-11 오노 야꾸힝 고교 가부시키가이샤 Pd-1/cd3 이중 특이성 단백질에 의한 혈액암 치료
JPWO2021025140A1 (sv) 2019-08-08 2021-02-11
WO2023201339A1 (en) 2022-04-15 2023-10-19 Kyverna Therapeutics, Inc. Methods and compositions for treating autoimmune disease
US20250249112A1 (en) * 2022-04-29 2025-08-07 Craig RAMIREZ Macropinocytosis selective non-binding protein-drug conjugates
US20250223326A1 (en) 2022-05-10 2025-07-10 Institut National de la Santé et de la Recherche Médicale Syncitin-1 fusion proteins and uses thereof for cargo delivery into target cells
TW202525845A (zh) 2023-08-23 2025-07-01 法商賽諾菲公司 基於ｃｔｌａ—４之溶體降解劑及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL74909A (en) 1984-04-20 1992-01-15 Genentech Inc Preparation of functional human factor viii and dna sequences,expression vectors,transformed microorganisms and cell lines used therein
SE8501050D0 (sv) 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
SE465222C5 (sv) 1989-12-15 1998-02-10 Pharmacia & Upjohn Ab Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning
SE468050C (sv) 1991-03-15 1998-04-27 Pharmacia & Upjohn Ab Rekombinant derivat av human faktor VIII
SE9400088D0 (sv) 1994-01-14 1994-01-14 Kabi Pharmacia Ab Bacterial receptor structures

Also Published As

Publication number Publication date
JP2002542259A (ja) 2002-12-10
DE60041052D1 (de) 2009-01-22
ATE417058T1 (de) 2008-12-15
WO2000063243A1 (en) 2000-10-26
AU4162400A (en) 2000-11-02
EP1179014B1 (en) 2008-12-10
DK1179014T3 (da) 2009-04-06
EP1179014A1 (en) 2002-02-13
JP4578690B2 (ja) 2010-11-10

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