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SG11201600048VA - Novel fused pyrimidine compound or salt thereof - Google Patents

Novel fused pyrimidine compound or salt thereof

Info

Publication number
SG11201600048VA
SG11201600048VA SG11201600048VA SG11201600048VA SG11201600048VA SG 11201600048V A SG11201600048V A SG 11201600048VA SG 11201600048V A SG11201600048V A SG 11201600048VA SG 11201600048V A SG11201600048V A SG 11201600048VA SG 11201600048V A SG11201600048V A SG 11201600048VA
Authority
SG
Singapore
Prior art keywords
salt
pyrimidine compound
fused pyrimidine
novel fused
novel
Prior art date
Application number
SG11201600048VA
Inventor
Satoru Iguchi
Fumihito Hosoi
Takeshi Sagara
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of SG11201600048VA publication Critical patent/SG11201600048VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SG11201600048VA 2013-08-12 2014-08-11 Novel fused pyrimidine compound or salt thereof SG11201600048VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013167600 2013-08-12
PCT/JP2014/071158 WO2015022926A1 (en) 2013-08-12 2014-08-11 Novel fused pyrimidine compound or salt thereof

Publications (1)

Publication Number Publication Date
SG11201600048VA true SG11201600048VA (en) 2016-03-30

Family

ID=52468312

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201600048VA SG11201600048VA (en) 2013-08-12 2014-08-11 Novel fused pyrimidine compound or salt thereof

Country Status (22)

Country Link
US (1) US9580432B2 (en)
EP (1) EP2947086B1 (en)
JP (1) JP6035423B2 (en)
KR (1) KR101828187B1 (en)
CN (1) CN105452257B (en)
AU (1) AU2014307437B2 (en)
BR (1) BR112016002069B1 (en)
CA (1) CA2921208C (en)
DK (1) DK2947086T3 (en)
ES (1) ES2661733T3 (en)
HU (1) HUE036834T2 (en)
MX (1) MX360498B (en)
MY (1) MY171831A (en)
NO (1) NO2947086T3 (en)
PH (1) PH12015502737B1 (en)
PL (1) PL2947086T3 (en)
PT (1) PT2947086T (en)
RU (1) RU2666349C2 (en)
SG (1) SG11201600048VA (en)
TR (1) TR201802875T4 (en)
TW (1) TWI585089B (en)
WO (1) WO2015022926A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3035936T3 (en) 2013-08-23 2019-08-30 Neupharma, Inc. Certain chemical entities, compositions, and methods
BR112017016318B1 (en) * 2015-01-30 2023-09-26 Taiho Pharmaceutical Co., Ltd FUMARIC ACID SALT, BTK INHIBITOR, PHARMACEUTICAL COMPOSITION AND ANTITUMORAL AGENT COMPRISING SAID SALT AND USE OF SAID SALT
MX381234B (en) * 2015-01-30 2025-03-12 Taiho Pharmaceutical Co Ltd PREVENTIVE AND/OR THERAPEUTIC AGENT OF IMMUNE DISEASE.
PL3345907T3 (en) * 2015-09-01 2020-09-07 Taiho Pharmaceutical Co., Ltd. Pyrazolo[3,4-d]pyrimidine compounds or salts thereof
MA41559A (en) * 2015-09-08 2017-12-26 Taiho Pharmaceutical Co Ltd CONDENSED PYRIMIDINE COMPOUND OR A SALT THEREOF
TWI642671B (en) * 2015-10-28 2018-12-01 台灣神隆股份有限公司 Process for preparing ibrutinib and its intermediates
MY199511A (en) 2016-02-23 2023-11-02 Taiho Pharmaceutical Co Ltd Novel condensed pyrimidine compound or salt thereof
CA3033370A1 (en) * 2016-08-15 2018-02-22 Neupharma, Inc. Certain chemical entities, compositions, and methods
AU2018228114B2 (en) * 2017-02-28 2022-04-07 Taiho Pharmaceutical Co., Ltd. AGENT ENHANCING ANTITUMOR EFFECT USING PYRAZOLO[3,4-d]PYRIMIDINE COMPOUND
MY201941A (en) 2017-08-21 2024-03-25 Taiho Pharmaceutical Co Ltd Fusion protein of dctn1 protein with ret protein
MX2021008252A (en) * 2019-01-11 2021-08-16 Taiho Pharmaceutical Co Ltd PYRIMIDINE COMPOUND OR SALT THEREOF.
WO2020188015A1 (en) 2019-03-21 2020-09-24 Onxeo A dbait molecule in combination with kinase inhibitor for the treatment of cancer
EP4054579A1 (en) 2019-11-08 2022-09-14 Institut National de la Santé et de la Recherche Médicale (INSERM) Methods for the treatment of cancers that have acquired resistance to kinase inhibitors
US20230064254A1 (en) * 2019-12-19 2023-03-02 Taiho Pharmaceutical Co., Ltd. Therapeutic agent containing fused pyrimidine compound as active ingredient
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
TW202216151A (en) * 2020-07-15 2022-05-01 日商大鵬藥品工業股份有限公司 Pyrimidine compound-containing combination to be used in tumor treatment
WO2022140246A1 (en) 2020-12-21 2022-06-30 Hangzhou Jijing Pharmaceutical Technology Limited Methods and compounds for targeted autophagy
CN114736207B (en) * 2022-04-28 2023-03-31 武汉九州钰民医药科技有限公司 Preparation process of small molecule HER2 inhibitor

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007509939A (en) 2003-10-27 2007-04-19 ジェネラブズ テクノロジーズ インコーポレーティッド Nucleoside compounds for treating viral infections
EP1968979A2 (en) 2005-12-08 2008-09-17 Abbott Laboratories 9-membered heterobicyclic compounds as inhibitors of protein kinases
CN101460161A (en) 2006-03-29 2009-06-17 弗尔德里克斯制药股份有限公司 Inhibition of alpha-synuclein toxicity
US8987233B2 (en) 2006-11-03 2015-03-24 Pharmacyclics, Inc. Bruton's tyrosine kinase activity probe and method of using
EP2560007A1 (en) * 2007-03-28 2013-02-20 Pharmacyclics, Inc. Identification of bruton's tyrosine kinase inhibitors
WO2009057733A1 (en) * 2007-10-31 2009-05-07 Santen Pharmaceutical Co., Ltd. Novel indole derivative having anti-angiogenic activity
NZ603525A (en) 2008-06-27 2015-02-27 Celgene Avilomics Res Inc Pyrimidine based compound and uses thereof
US8338439B2 (en) 2008-06-27 2012-12-25 Celgene Avilomics Research, Inc. 2,4-disubstituted pyrimidines useful as kinase inhibitors
CA2841080A1 (en) * 2011-07-13 2013-01-17 Pharmacyclics, Inc. Inhibitors of bruton's tyrosine kinase
CN105771039B (en) * 2011-07-15 2020-01-10 赛诺菲-安万特德国有限公司 Drug delivery device
ES2516392T3 (en) 2012-01-19 2014-10-30 Taiho Pharmaceutical Co., Ltd. 3,5-disubstituted alkynylbenzene compound and salt thereof
CN104250250A (en) * 2013-06-25 2014-12-31 苏州科捷生物医药有限公司 4-aromatic aminopyrimidine compound and anti-tumor use thereof

Also Published As

Publication number Publication date
CA2921208C (en) 2018-02-20
US20160115168A1 (en) 2016-04-28
PL2947086T3 (en) 2018-06-29
PT2947086T (en) 2018-03-09
TW201536786A (en) 2015-10-01
EP2947086A4 (en) 2016-06-22
JPWO2015022926A1 (en) 2017-03-02
AU2014307437B2 (en) 2016-12-15
MY171831A (en) 2019-11-01
BR112016002069A2 (en) 2017-08-01
KR20160038891A (en) 2016-04-07
PH12015502737A1 (en) 2016-03-07
MX360498B (en) 2018-11-05
KR101828187B1 (en) 2018-02-09
CA2921208A1 (en) 2015-02-19
HK1217703A1 (en) 2017-01-20
CN105452257B (en) 2017-09-05
AU2014307437A1 (en) 2016-01-21
TWI585089B (en) 2017-06-01
BR112016002069B1 (en) 2020-08-18
RU2666349C2 (en) 2018-09-07
JP6035423B2 (en) 2016-11-30
DK2947086T3 (en) 2018-03-19
ES2661733T3 (en) 2018-04-03
HUE036834T2 (en) 2018-08-28
MX2016001845A (en) 2016-05-16
TR201802875T4 (en) 2018-03-21
EP2947086A1 (en) 2015-11-25
RU2015156524A (en) 2017-09-14
CN105452257A (en) 2016-03-30
WO2015022926A1 (en) 2015-02-19
EP2947086B1 (en) 2018-01-03
NO2947086T3 (en) 2018-06-02
PH12015502737B1 (en) 2018-08-31
US9580432B2 (en) 2017-02-28

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