TN2009000135A1 - Use of modified cyclosporins - Google Patents

Use of modified cyclosporins

Info

Publication number: TN2009000135A1
Authority: TN; Tunisia
Prior art keywords: cyclosporins; modified; modified cyclosporins; prevention; treatment
Prior art date: 2006-10-12

Application number

TNP2009000135A

Other languages

English (en)

Inventor

Motoyuki Kohjima

Makoto Nakamuta

Original Assignee

Univ Kyushu

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-10-12

Filing date

2009-04-10

Publication date

2010-10-18

2009-04-10 Application filed by Univ Kyushu, Novartis Ag filed Critical Univ Kyushu

2010-10-18 Publication of TN2009000135A1 publication Critical patent/TN2009000135A1/fr

Links

229930182912 cyclosporin Natural products 0.000 title abstract 2
108010036941 Cyclosporins Proteins 0.000 title 1
102000001493 Cyclophilins Human genes 0.000 abstract 1
108010068682 Cyclophilins Proteins 0.000 abstract 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
230000001506 immunosuppresive effect Effects 0.000 abstract 1
208000019423 liver disease Diseases 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Gastroenterology & Hepatology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Transplantation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

TNP2009000135A 2006-10-12 2009-04-10 Use of modified cyclosporins TN2009000135A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US82922806P	2006-10-12	2006-10-12
PCT/EP2007/060794 WO2008043797A1 (fr)	2006-10-12	2007-10-10	Utilisation de cyclosporines modifiées

Publications (1)

Publication Number	Publication Date
TN2009000135A1 true TN2009000135A1 (en)	2010-10-18

Family

ID=39092021

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TNP2009000135A TN2009000135A1 (en)	2006-10-12	2009-04-10	Use of modified cyclosporins

Country Status (17)

Country	Link
US (1)	US20100130408A1 (fr)
EP (1)	EP2073831A1 (fr)
JP (1)	JP5455632B2 (fr)
KR (1)	KR20090083902A (fr)
CN (1)	CN101557819A (fr)
AU (1)	AU2007306316B2 (fr)
BR (1)	BRPI0719189A2 (fr)
CA (1)	CA2665415A1 (fr)
IL (1)	IL197966A0 (fr)
MA (1)	MA30865B1 (fr)
MX (1)	MX2009003743A (fr)
NO (1)	NO20091694L (fr)
RU (1)	RU2463071C2 (fr)
SG (1)	SG175621A1 (fr)
TN (1)	TN2009000135A1 (fr)
WO (1)	WO2008043797A1 (fr)
ZA (1)	ZA200902300B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20110117055A1 (en)	2009-11-19	2011-05-19	Macdonald James E	Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
CN101843893B (zh) *	2010-05-21	2012-02-01	中国人民解放军第三军医大学	环孢素a在制备抗轮状病毒药物中的应用
EP3351247A1 (fr) *	2010-06-01	2018-07-25	Auspex Pharmaceutical, Inc.	Inhibiteurs benzoquinolone de vmat2
JP6362601B2 (ja)	2012-09-18	2018-07-25	オースペックス・ファーマシューティカルズ・インコーポレイテッドＡｕｓｐｅｘＰｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ．	小胞モノアミン輸送体２の重水素化ベンゾキノリン阻害剤の製剤薬物動態
US9550780B2 (en)	2012-09-18	2017-01-24	Auspex Pharmaceuticals, Inc.	Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
JP6542222B2 (ja)	2013-12-03	2019-07-10	オースペックスファーマシューティカルズインコーポレイテッド	ベンゾキノリン化合物の製造方法
HK1249860A1 (zh)	2015-03-06	2018-11-16	奥斯拜客斯制药有限公司	用於治疗异常不自主运动障碍的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5639724A (en) *	1984-07-24	1997-06-17	Sandoz Ltd.	Cyclosporin galenic forms
US5908621A (en) *	1995-11-02	1999-06-01	Schering Corporation	Polyethylene glycol modified interferon therapy
FR2757521B1 (fr) *	1996-12-24	1999-01-29	Rhone Poulenc Rorer Sa	Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757522B1 (fr) *	1996-12-24	1999-01-29	Rhone Poulenc Rorer Sa	Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
JPH1180026A (ja) *	1997-09-02	1999-03-23	Yoshitomi Pharmaceut Ind Ltd	新規免疫抑制剤、その使用方法およびその同定方法
US20030216303A1 (en) *	1998-03-06	2003-11-20	Michael Ambuhl	Emulsion preconcentrates containing cyclosporin or a macrolide
JP4350898B2 (ja) *	1998-07-01	2009-10-21	デビオファーム・ソシエテ・アノニム	活性の特徴が改善された新規のシクロスポリン
ES2365692T3 (es) *	1999-04-27	2011-10-10	Mitsubishi Tanabe Pharma Corporation	Medicamento para la prevención o tratamiento terapéutico de enfermedades hepáticas.
AU2001292301A1 (en) *	2000-10-11	2002-04-22	Daiichi Pharmaceutical Co., Ltd.	Novel drugs for liver diseases
US20030213603A1 (en) *	2002-05-14	2003-11-20	Fisher David B.	Dual use extension apparatus for a tool
GB0320638D0 (en) *	2003-09-03	2003-10-01	Novartis Ag	Organic compounds
US7079552B2 (en) *	2003-09-09	2006-07-18	Harris Corporation	Mobile ad hoc network (MANET) with quality-of-service (QoS) protocol hierarchy and related methods
EP1802650B1 (fr) *	2004-10-01	2011-10-26	Scynexis, Inc.	Derives de cyclosporine 3-ether et 3-thioether substitues utilises dans le traitement et la prevention d'une infection par hepatite c
ES2357587T3 (es) *	2004-10-01	2011-04-27	Debiopharm S.A.	Uso de (d-meala)3-(etval)4-ciclosporina para el tratamiento de infección por hepatitis c.
WO2006071619A1 (fr) *	2004-12-23	2006-07-06	Novartis Ag	Compositions pour le traitement du vhc
US8512690B2 (en) *	2009-04-10	2013-08-20	Novartis Ag	Derivatised proline containing peptide compounds as protease inhibitors

2007
- 2007-10-10 WO PCT/EP2007/060794 patent/WO2008043797A1/fr active Application Filing
- 2007-10-10 KR KR1020097009615A patent/KR20090083902A/ko not_active Ceased
- 2007-10-10 SG SG2011074572A patent/SG175621A1/en unknown
- 2007-10-10 RU RU2009117699/15A patent/RU2463071C2/ru not_active IP Right Cessation
- 2007-10-10 US US12/444,941 patent/US20100130408A1/en not_active Abandoned
- 2007-10-10 JP JP2009531841A patent/JP5455632B2/ja not_active Expired - Fee Related
- 2007-10-10 AU AU2007306316A patent/AU2007306316B2/en not_active Ceased
- 2007-10-10 CA CA002665415A patent/CA2665415A1/fr not_active Abandoned
- 2007-10-10 BR BRPI0719189A patent/BRPI0719189A2/pt not_active IP Right Cessation
- 2007-10-10 EP EP07821161A patent/EP2073831A1/fr not_active Withdrawn
- 2007-10-10 MX MX2009003743A patent/MX2009003743A/es active IP Right Grant
- 2007-10-10 CN CNA2007800410447A patent/CN101557819A/zh active Pending
2009
- 2009-04-02 ZA ZA200902300A patent/ZA200902300B/xx unknown
- 2009-04-05 IL IL197966A patent/IL197966A0/en unknown
- 2009-04-10 TN TNP2009000135A patent/TN2009000135A1/fr unknown
- 2009-04-28 NO NO20091694A patent/NO20091694L/no not_active Application Discontinuation
- 2009-05-06 MA MA31842A patent/MA30865B1/fr unknown

Also Published As

Publication number	Publication date
MX2009003743A (es)	2009-06-18
ZA200902300B (en)	2010-10-27
IL197966A0 (en)	2011-08-01
EP2073831A1 (fr)	2009-07-01
MA30865B1 (fr)	2009-11-02
WO2008043797A1 (fr)	2008-04-17
US20100130408A1 (en)	2010-05-27
KR20090083902A (ko)	2009-08-04
JP5455632B2 (ja)	2014-03-26
CA2665415A1 (fr)	2008-04-17
AU2007306316A1 (en)	2008-04-17
BRPI0719189A2 (pt)	2018-08-14
SG175621A1 (en)	2011-11-28
AU2007306316B2 (en)	2011-10-27
CN101557819A (zh)	2009-10-14
NO20091694L (no)	2009-07-10
RU2463071C2 (ru)	2012-10-10
JP2010505912A (ja)	2010-02-25
RU2009117699A (ru)	2010-11-20

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