TN2018000345A1 - Trispecific and/or trivalent binding proteins - Google Patents
Trispecific and/or trivalent binding proteinsInfo
- Publication number
- TN2018000345A1 TN2018000345A1 TNP/2018/000345A TN2018000345A TN2018000345A1 TN 2018000345 A1 TN2018000345 A1 TN 2018000345A1 TN 2018000345 A TN2018000345 A TN 2018000345A TN 2018000345 A1 TN2018000345 A1 TN 2018000345A1
- Authority
- TN
- Tunisia
- Prior art keywords
- trispecific
- binding proteins
- proteins
- binding
- trivalent
- Prior art date
Links
- 102000014914 Carrier Proteins Human genes 0.000 title abstract 6
- 108091008324 binding proteins Proteins 0.000 title abstract 6
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000009977 dual effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
The disclosure provides trispecific and/or trivalent binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind one or more target proteins, wherein a first pair of polypeptides forming the binding protein possess dual variable domains having a cross-over orientation and wherein a second pair of polypeptides forming the binding protein posscss a single variable domain. The disclosure also provides methods for making trispecific and/or trivalent binding proteins and uses of such binding proteins.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662322036P | 2016-04-13 | 2016-04-13 | |
| US201662331191P | 2016-05-03 | 2016-05-03 | |
| US201662412187P | 2016-10-24 | 2016-10-24 | |
| EP17305298 | 2017-03-17 | ||
| PCT/US2017/027488 WO2017180913A2 (en) | 2016-04-13 | 2017-04-13 | Trispecific and/or trivalent binding proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2018000345A1 true TN2018000345A1 (en) | 2020-06-15 |
Family
ID=69629979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP/2018/000345A TN2018000345A1 (en) | 2016-04-13 | 2017-04-13 | Trispecific and/or trivalent binding proteins |
Country Status (3)
| Country | Link |
|---|---|
| EC (1) | ECSP18084491A (en) |
| TN (1) | TN2018000345A1 (en) |
| ZA (1) | ZA201806629B (en) |
-
2017
- 2017-04-13 TN TNP/2018/000345A patent/TN2018000345A1/en unknown
-
2018
- 2018-10-05 ZA ZA2018/06629A patent/ZA201806629B/en unknown
- 2018-11-12 EC ECSENADI201884491A patent/ECSP18084491A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ECSP18084491A (en) | 2019-01-31 |
| ZA201806629B (en) | 2021-06-30 |
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