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TW200626136A - Low oil emulsion compositions for delivering taxoids and other insoluble drugs - Google Patents

Low oil emulsion compositions for delivering taxoids and other insoluble drugs

Info

Publication number
TW200626136A
TW200626136A TW094133774A TW94133774A TW200626136A TW 200626136 A TW200626136 A TW 200626136A TW 094133774 A TW094133774 A TW 094133774A TW 94133774 A TW94133774 A TW 94133774A TW 200626136 A TW200626136 A TW 200626136A
Authority
TW
Taiwan
Prior art keywords
taxoids
delivering
oil emulsion
low oil
insoluble drugs
Prior art date
Application number
TW094133774A
Other languages
English (en)
Chinese (zh)
Inventor
Andrew Xian Chen
Original Assignee
Andrew Xian Chen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Andrew Xian Chen filed Critical Andrew Xian Chen
Publication of TW200626136A publication Critical patent/TW200626136A/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113Multiple emulsions, e.g. oil-in-water-in-oil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
TW094133774A 2004-09-28 2005-09-28 Low oil emulsion compositions for delivering taxoids and other insoluble drugs TW200626136A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/952,243 US8557861B2 (en) 2004-09-28 2004-09-28 Low oil emulsion compositions for delivering taxoids and other insoluble drugs

Publications (1)

Publication Number Publication Date
TW200626136A true TW200626136A (en) 2006-08-01

Family

ID=36099405

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094133774A TW200626136A (en) 2004-09-28 2005-09-28 Low oil emulsion compositions for delivering taxoids and other insoluble drugs

Country Status (14)

Country Link
US (1) US8557861B2 (fr)
EP (1) EP1804765A4 (fr)
JP (1) JP2008514720A (fr)
KR (1) KR20070063023A (fr)
CN (1) CN101094646A (fr)
AU (1) AU2005289398A1 (fr)
CA (1) CA2581635A1 (fr)
IL (1) IL182069A0 (fr)
MX (1) MX2007003727A (fr)
NO (1) NO20071651L (fr)
RU (1) RU2007116149A (fr)
TW (1) TW200626136A (fr)
WO (1) WO2006037089A2 (fr)
ZA (1) ZA200702536B (fr)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8557861B2 (en) 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
US20060067953A1 (en) * 2004-09-29 2006-03-30 Conforma Therapeutics Corporation Oral pharmaceutical formulations and methods for producing and using same
CA2620585C (fr) * 2005-08-31 2015-04-28 Abraxis Bioscience, Llc Compositions comprenant des agents pharmaceutiques peu solubles dans l'eau et des agents antimicrobiens
TWI376239B (en) * 2006-02-01 2012-11-11 Andrew Xian Chen Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof
WO2007134354A1 (fr) * 2006-05-23 2007-11-29 Ebewe Pharma Ges.M.B.H. Nfg. Kg Formulation pharmaceutique
JP5571380B2 (ja) * 2006-07-24 2014-08-13 ルミナス バイオサイエンシズ,インコーポレイテッド オストワルド熟成を減少させた水不溶性の医薬品物質の固体ナノ粒子処方物
EP2081562B1 (fr) 2006-09-20 2016-02-24 The Board of Regents of The University of Texas System Procédé pour administrer des anesthésiants volatils pour une anesthésie locale et/ou le soulagement de la douleur
WO2008042841A2 (fr) * 2006-10-02 2008-04-10 Dr. Reddy's Laboratories Limited Compositions du docétaxel
EP2025333A1 (fr) * 2007-08-14 2009-02-18 Pharmatex Italia Srl Formules pharmaceutiques injectables de taxoïdes
CN101396354B (zh) * 2007-09-30 2010-12-01 江苏恒瑞医药股份有限公司 一种稳定的塔三烷类化合物液体组合物及其制备方法和其应用
FR2922107B1 (fr) * 2007-10-10 2010-02-26 Aventis Pharma Sa Nouvelles compositions a base de taxoides
EP2077132A1 (fr) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif distributeur, dispositif de stockage et procédé pour la distribution d'une formulation
ES2765007T3 (es) 2008-01-22 2020-06-05 Univ Texas Composiciones anestésicas volátiles y métodos de uso
EP3581169A1 (fr) 2008-01-22 2019-12-18 The Board Of Regents Of The University Of Texas System Compositions anesthésiques volatiles comprenant des solvants d'extraction pour une anesthésie régionale et/ou un soulagement de la douleur
AU2014277860A1 (en) * 2008-01-22 2015-01-22 Board Of Regents, The University Of Texas System Volatile anesthetic compositions and methods of use
AU2008354007A1 (en) * 2008-04-04 2009-10-08 Robert Rodriguez Lipid-oil-water nanoemulsion delivery system for microtubule-interacting agents
EP2317978A2 (fr) * 2008-07-23 2011-05-11 Bharat Serums And Vaccines Ltd. Nanoémulsion huile dans l'eau injectable stable de docétaxel
FR2934953B1 (fr) 2008-08-14 2011-01-21 Commissariat Energie Atomique Nanoemulsions de nanocristaux
FR2934955B1 (fr) * 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions
FR2934954B1 (fr) 2008-08-14 2011-07-22 Commissariat Energie Atomique Emulsion fluorescente de vert d'indocyanine
EP2204167A1 (fr) 2009-01-05 2010-07-07 Azad Pharma AG Microémulsion pharmaceutique pour la prévention de l'agrégation supramoléculaire de molécules amphiphiles
US20110071090A1 (en) * 2009-03-11 2011-03-24 Stable Solutions Llc Method of mitigating adverse drug events using omega-3-fatty acids as a parenteral therapeutic drug vehicle
US9034389B2 (en) 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US8993625B2 (en) * 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
EP2662472B1 (fr) 2009-03-31 2019-02-27 Boehringer Ingelheim International Gmbh Procédé de revêtement d'une surface d'un composant
CN109394689A (zh) * 2009-05-05 2019-03-01 德州大学系统董事会 挥发性麻醉剂的新型制剂及其用于减轻炎症的使用方法
WO2010133294A2 (fr) 2009-05-18 2010-11-25 Boehringer Ingelheim International Gmbh Adapteur, dispositif d'inhalation et nébuliseur
CN102038635A (zh) 2009-10-23 2011-05-04 天津天士力集团有限公司 一种含有pH值调节剂的紫杉烷类药物溶液及其制备方法
CN102038636B (zh) * 2009-10-23 2014-08-13 天士力控股集团有限公司 一种含有螯合剂的紫杉烷类药物溶液及其制备方法
CN102048688B (zh) * 2009-10-29 2014-03-05 中国医学科学院药物研究所 以胆固醇复合物为中间载体的紫杉醇亚微乳
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
EP2504051B1 (fr) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nébuliseur
MX2012005961A (es) 2009-11-25 2012-06-14 Boehringer Ingelheim Int Nebulizador.
TWI438009B (zh) * 2010-02-19 2014-05-21 Teikoku Pharma Usa Inc 紫杉烷前-乳劑調配物及其製造與使用之方法
US10703722B2 (en) 2010-04-27 2020-07-07 Calcimedica, Inc. Compounds that modulate intracellular calcium
NZ603828A (en) * 2010-05-03 2015-09-25 Teikoku Pharma Usa Inc Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
CN102939077B (zh) * 2010-06-03 2016-04-06 莱迪杜德制药公司 含有维生素k的纳米乳液组合物
US9943654B2 (en) 2010-06-24 2018-04-17 Boehringer Ingelheim International Gmbh Nebulizer
KR101793101B1 (ko) * 2010-08-20 2017-11-02 닥터 레디스 래보러토리즈 에스에이 인지질 데포
JP2012051823A (ja) * 2010-08-31 2012-03-15 Fujifilm Corp 難容性薬物含有水中油型乳化組成物及びその製造方法
CN101926757B (zh) * 2010-09-01 2013-01-02 北京大学 一种难溶性药物的液体组合物及其制备方法
EP2694220B1 (fr) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Appareil médical pourvu d'un récipient
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
US8586527B2 (en) 2011-10-20 2013-11-19 Jaipal Singh Cerivastatin to treat pulmonary disorders
EP2797585A4 (fr) * 2011-12-29 2015-10-07 Latitude Pharmaceuticals Inc Nanoémulsions de glucagon stabilisées
IL286348B2 (en) 2012-01-23 2023-04-01 Sage Therapeutics Inc Pharmaceutical preparations that include allopregnanolone
WO2013127727A1 (fr) * 2012-02-29 2013-09-06 B. Braun Melsungen Ag Émulsion contenant des hormones comprenant des phospholipides de krill
WO2013152894A1 (fr) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Pulvérisateur comprenant des moyens de détrompage
WO2013168172A1 (fr) 2012-05-10 2013-11-14 Painreform Ltd. Préparations de dépôt d'un anesthésiant local et procédés de préparation associés
PL2887944T3 (pl) 2012-08-21 2022-02-21 Sage Therapeutics, Inc. Allopregnanolon do leczenia lekoopornego stanu padaczkowego
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
EP2908838A4 (fr) * 2012-10-16 2016-12-21 Inspyr Therapeutics Inc Compositions anticancéreuses injectables
KR101951933B1 (ko) 2013-03-12 2019-02-25 주식회사 아리바이오 라이소포스파티딜콜린 또는 이의 유도체를 포함하는 지질나노물질 및 이의 제조방법
US20140275261A1 (en) 2013-03-15 2014-09-18 Dr. Reddy's Laboratories, Inc. Diclofenac parenteral compositions
CN103301062A (zh) * 2013-06-03 2013-09-18 四川百利药业有限责任公司 一种中长链脂肪乳注射液的制备方法
EP3030298B1 (fr) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nébuliseur
EP2835146B1 (fr) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Atomiseur
KR101439898B1 (ko) * 2013-08-12 2014-09-17 박승재 상황버섯을 이용한 고품질 코코넛오일의 제조방법
JP6745225B2 (ja) 2014-05-07 2020-08-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 容器、表示デバイス、及びネブライザ
EA032850B1 (ru) 2014-05-07 2019-07-31 Бёрингер Ингельхайм Интернациональ Гмбх Контейнер, небулайзер и способ изготовления контейнера
ES2874029T3 (es) 2014-05-07 2021-11-04 Boehringer Ingelheim Int Nebulizador
CN107106659B (zh) 2014-10-27 2022-07-08 莱迪杜德制药公司 肠胃外胰高血糖素制剂
CN104473869A (zh) * 2014-11-20 2015-04-01 北京京科泰来科技有限公司 一种艾司洛尔脂肪乳及其制备方法
US10413508B2 (en) 2015-02-06 2019-09-17 R. P. Scherer Technologies, Llc Preparation of an oil-in-water emulsion for polymer stabilized pharmaceutical formulations
ES2899197T3 (es) 2015-02-27 2022-03-10 Calcimedica Inc Tratamiento de la pancreatitis
US10500285B2 (en) * 2015-05-15 2019-12-10 Zhuhai Beihai Biotech Co., Ltd. Docetaxel and human serum albumin complexes
MX2018015112A (es) * 2016-06-07 2019-09-09 Targagenix Inc Composiciones de nanoemulsión de fármacos taxoides, y métodos para su uso para actuar sobre células cancerosas y células madre cancerosas.
EP3573610A4 (fr) * 2017-01-26 2021-01-13 Calcimedica, Inc. Compositions d'inhibiteur de canal crac
US20240315968A1 (en) * 2023-03-24 2024-09-26 Insitu Biologics, Inc. Sustained release cancer therapeutics formulations

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1792410B2 (de) * 1967-09-01 1980-03-13 Apoteksvarucentralen Vitrum Apotekareaktiebolaget, Stockholm Arzneimittelzubereitung zur intravenösen Injektion
US4816247A (en) * 1985-09-11 1989-03-28 American Cyanamid Company Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs
KR0154343B1 (ko) * 1990-11-06 1998-11-16 아만 히데아키 동결 건조 제제 및 이의 제조방법
IL101007A (en) * 1992-02-18 1997-08-14 Pharmos Ltd Dry stable compositions prepared by lyophilization
CA2086874E (fr) * 1992-08-03 2000-01-04 Renzo Mauro Canetta Methodes d'administration du taxol
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US5478860A (en) * 1993-06-04 1995-12-26 Inex Pharmaceuticals Corp. Stable microemulsions for hydrophobic compound delivery
US5415869A (en) * 1993-11-12 1995-05-16 The Research Foundation Of State University Of New York Taxol formulation
GB9405593D0 (en) * 1994-03-22 1994-05-11 Zeneca Ltd Pharmaceutical compositions
FR2718963B1 (fr) * 1994-04-25 1996-05-24 Rhone Poulenc Rorer Sa Nouvelle composition pharmaceutique à base de taxoïdes.
US5616330A (en) 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
US5635536A (en) 1994-12-07 1997-06-03 Pharmacia & Upjohn Aktiebolag Emulsion suitable for administering a sphingolipid
US6231600B1 (en) * 1995-02-22 2001-05-15 Scimed Life Systems, Inc. Stents with hybrid coating for medical devices
WO1997009986A1 (fr) * 1995-09-13 1997-03-20 Nippon Shinyaku Co., Ltd. Preparation lyophilisee contenant de la pge1 et son procede de production
US6245349B1 (en) * 1996-02-23 2001-06-12 éLAN CORPORATION PLC Drug delivery compositions suitable for intravenous injection
DE19612566C2 (de) 1996-03-29 1999-02-25 Siemens Ag Vorrichtung zum Verhindern von Doppelabzügen
US5660858A (en) 1996-04-03 1997-08-26 Research Triangle Pharmaceuticals Cyclosporin emulsions
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
GB9715759D0 (en) 1997-07-26 1997-10-01 Danbiosyst Uk New emulsion formulations
US20020006613A1 (en) * 1998-01-20 2002-01-17 Shyjan Andrew W. Methods and compositions for the identification and assessment of cancer therapies
DE69936911T2 (de) * 1998-02-10 2008-05-15 Sicor Inc., Irvine Propofolhaltiges arzneimittel enthaltend sulfite
US6979456B1 (en) * 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
US7030155B2 (en) * 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US7534443B1 (en) 1998-07-16 2009-05-19 Ichiro Azuma Preparations for immunotherapy for cancer having bacterial somatic constituent as the active ingredient
US6277413B1 (en) * 1998-07-17 2001-08-21 Skyepharma, Inc. Biodegradable compositions for the controlled release of encapsulated substances
DE19843968A1 (de) 1998-09-24 2000-04-13 Hans Dietl Taxane enthaltende pharmazeutische Zubereitung zur intravenösen Applikation und Verfahren zu ihrer Herstellung
US6028108A (en) * 1998-10-22 2000-02-22 America Home Products Corporation Propofol composition comprising pentetate
US6140373A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
US6455280B1 (en) * 1998-12-22 2002-09-24 Genset S.A. Methods and compositions for inhibiting neoplastic cell growth
DE19900054A1 (de) * 1999-01-04 2000-07-06 Hans Dietl Taxane enthaltende stabile und sterile Emulsion und Verfahren zu ihrer Herstellung
JP2000212067A (ja) 1999-01-19 2000-08-02 Towa Yakuhin Kk 薬物含有エマルジョン製剤
TW422706B (en) * 1999-07-01 2001-02-21 Wang Iz Rung An oil-in-water emulsion type of paclitaxel
ITMI991483A1 (it) * 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
US6136846A (en) * 1999-10-25 2000-10-24 Supergen, Inc. Formulation for paclitaxel
RU2003119140A (ru) 2000-12-28 2004-12-27 Дайити Фармасьютикал Ко., Лтд. (JP) Эмульсионный препарат
US20030099674A1 (en) * 2001-08-11 2003-05-29 Chen Andrew X. Lyophilized injectable formulations containing paclitaxel or other taxoid drugs
US6858227B1 (en) * 2001-11-21 2005-02-22 Sonus Pharmaceuticals, Inc. Vitamin E conjugates
JP2005249110A (ja) 2004-03-05 2005-09-15 Daijiro Nakamura 回転出力装置
US20050232952A1 (en) 2002-03-01 2005-10-20 Gregory Lambert Self emulsifying drug delivery systems for poorly soluble drugs
AU2003299590B8 (en) * 2002-12-09 2010-04-08 Abraxis Bioscience, Llc Compositions and methods of delivery of pharmacological agents
EP1510206A1 (fr) 2003-08-29 2005-03-02 Novagali Pharma SA Formulation huileuse auto-émulsifiable pour l'administration de principes actifs peu solubles dans l'eau
US7713440B2 (en) * 2003-10-08 2010-05-11 Lyotropic Therapeutics, Inc. Stabilized uncoated particles of reversed liquid crystalline phase materials
AU2004285037B2 (en) * 2003-10-29 2010-07-22 Sonus Pharmaceuticals, Inc. Tocopherol-modified therapeutic drug compounds
WO2005065676A1 (fr) 2004-01-09 2005-07-21 Otsuka Pharmaceutical Factory, Inc. Emulsion grasse contenant paclitaxel ou docetaxel
JP2005225818A (ja) 2004-02-13 2005-08-25 Otsuka Pharmaceut Factory Inc パクリタキセル又はドセタキセルの医薬組成物
US7871632B2 (en) * 2004-07-12 2011-01-18 Adventrx Pharmaceuticals, Inc. Compositions for delivering highly water soluble drugs
RU2007107359A (ru) * 2004-07-28 2008-09-10 ЭсДи ФАРМАСЬЮТИКАЛЗ, ИНК. (US) Стабильная инъецируемая композиция альфа-токоферилсукцината, его аналогов и солей
US8557861B2 (en) 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
TW200731991A (en) * 2005-12-20 2007-09-01 Sonus Pharma Inc Lipophilic di(anticancer drug) compounds, compositions and related methods

Also Published As

Publication number Publication date
US8557861B2 (en) 2013-10-15
MX2007003727A (es) 2007-06-05
IL182069A0 (en) 2007-07-24
JP2008514720A (ja) 2008-05-08
RU2007116149A (ru) 2008-11-10
ZA200702536B (en) 2009-08-26
CN101094646A (zh) 2007-12-26
US20060067952A1 (en) 2006-03-30
NO20071651L (no) 2007-06-21
AU2005289398A1 (en) 2006-04-06
EP1804765A4 (fr) 2012-09-05
EP1804765A2 (fr) 2007-07-11
KR20070063023A (ko) 2007-06-18
WO2006037089A3 (fr) 2007-01-25
WO2006037089A2 (fr) 2006-04-06
CA2581635A1 (fr) 2006-04-06

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