UA104738C2 - Композиция для повышения биосовместимости имплантатов и клеток для трансплантации с организмом реципиента и способ ее приготовления - Google Patents
Композиция для повышения биосовместимости имплантатов и клеток для трансплантации с организмом реципиента и способ ее приготовленияInfo
- Publication number
- UA104738C2 UA104738C2 UAA201106240A UAA201106240A UA104738C2 UA 104738 C2 UA104738 C2 UA 104738C2 UA A201106240 A UAA201106240 A UA A201106240A UA A201106240 A UAA201106240 A UA A201106240A UA 104738 C2 UA104738 C2 UA 104738C2
- Authority
- UA
- Ukraine
- Prior art keywords
- composition
- implants
- preparation
- recipient organism
- enhancing biocompatibility
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000002054 transplantation Methods 0.000 title abstract 3
- 230000002708 enhancing effect Effects 0.000 title abstract 2
- 239000007943 implant Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 210000002966 serum Anatomy 0.000 abstract 2
- 102000009027 Albumins Human genes 0.000 abstract 1
- 108010088751 Albumins Proteins 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 102000007562 Serum Albumin Human genes 0.000 abstract 1
- 108010071390 Serum Albumin Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000002513 implantation Methods 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Surgery (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Изобретение относится к медицине и ветеринарии и может быть использовано при трансплантации клеток, а также имплантации разных веществ и устройств органической и неорганической природы. Композиция для повышения биосовместимости имплантатов и клеток для трансплантации с организмом реципиента содержит альбумин сыворотки крови реципиента, а также дополнительно содержит аминокислоты, фосфор и ионы магния, натрия, калия и хлора. Способ получения композиции включает смешивание компонентов с последующим центрифугированием, содержание альбумина обеспечивают введением сыворотки крови реципиента, которая термически обработана при температуре 94-95 °C на протяжении 1-2 минут.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAA201106240A UA104738C2 (ru) | 2011-05-18 | 2011-05-18 | Композиция для повышения биосовместимости имплантатов и клеток для трансплантации с организмом реципиента и способ ее приготовления |
| PCT/UA2011/000045 WO2012158130A1 (en) | 2011-05-18 | 2011-06-01 | Substance enhancing biocompatibility of implants with recipient body and method of its preparation. |
| EP11757689.2A EP2709684B1 (en) | 2011-05-18 | 2011-06-01 | Substance enhancing biocompatibility of implants with recipient body and method of its preparation. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAA201106240A UA104738C2 (ru) | 2011-05-18 | 2011-05-18 | Композиция для повышения биосовместимости имплантатов и клеток для трансплантации с организмом реципиента и способ ее приготовления |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA104738C2 true UA104738C2 (ru) | 2014-03-11 |
Family
ID=44651919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201106240A UA104738C2 (ru) | 2011-05-18 | 2011-05-18 | Композиция для повышения биосовместимости имплантатов и клеток для трансплантации с организмом реципиента и способ ее приготовления |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP2709684B1 (ru) |
| UA (1) | UA104738C2 (ru) |
| WO (1) | WO2012158130A1 (ru) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9606452D0 (en) | 1996-03-27 | 1996-06-05 | Sandoz Ltd | Organic compounds |
| JP2003521351A (ja) * | 2000-02-04 | 2003-07-15 | イソティス エヌ．ブイ． | 蛋白質性コーティング |
| UA56960C2 (en) | 2003-01-30 | 2005-07-15 | Ltd Liability Company Trust Ma | Composition for increasing implant biocompatibility with body of recipient |
| US20060008497A1 (en) * | 2004-07-09 | 2006-01-12 | Shlomo Gabbay | Implantable apparatus having improved biocompatibility and process of making the same |
| UA20638U (en) | 2006-03-28 | 2007-02-15 | Oleh Mykolaiovych Lazarenko | Composition for increasing biocompatibility of implant with recipient's body |
-
2011
- 2011-05-18 UA UAA201106240A patent/UA104738C2/ru unknown
- 2011-06-01 EP EP11757689.2A patent/EP2709684B1/en not_active Not-in-force
- 2011-06-01 WO PCT/UA2011/000045 patent/WO2012158130A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| EP2709684A1 (en) | 2014-03-26 |
| WO2012158130A1 (en) | 2012-11-22 |
| EP2709684B1 (en) | 2016-05-25 |
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