[go: up one dir, main page]

UA102254C2 - Жидкий состав для деферипрона с приятным вкусом - Google Patents

Жидкий состав для деферипрона с приятным вкусом

Info

Publication number
UA102254C2
UA102254C2 UAA201013859A UAA201013859A UA102254C2 UA 102254 C2 UA102254 C2 UA 102254C2 UA A201013859 A UAA201013859 A UA A201013859A UA A201013859 A UAA201013859 A UA A201013859A UA 102254 C2 UA102254 C2 UA 102254C2
Authority
UA
Ukraine
Prior art keywords
heading
deferiprone
effective amount
taste
liquid formulation
Prior art date
Application number
UAA201013859A
Other languages
English (en)
Ukrainian (uk)
Inventor
Майкл Спино
Анита Хви
Цихуа Янг
Мохамед Н. Кабир
Original Assignee
Апотекс Технолоджис Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Апотекс Технолоджис Инк. filed Critical Апотекс Технолоджис Инк.
Publication of UA102254C2 publication Critical patent/UA102254C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение касается негорького и приятного на вкус жидкого перорального фармацевтического состава, который включает деферипрон и композицию, которая маскирует вкус, причем указанная композиция, которая маскирует вкус, включает эффективное количество высокоинтенсивного искусственного подсластителя на литр состава, эффективное количество гидроксиэтилцеллюлозы на литр состава, и эффективное количество глицерина на литр состава, и эффективное количество, по меньшей мере, одного ароматизирущего средства.
UAA201013859A 2008-04-25 2008-04-25 Жидкий состав для деферипрона с приятным вкусом UA102254C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CA2008/000784 WO2009129592A1 (en) 2008-04-25 2008-04-25 Liquid formulation for deferiprone with palatable taste

Publications (1)

Publication Number Publication Date
UA102254C2 true UA102254C2 (ru) 2013-06-25

Family

ID=41216357

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201013859A UA102254C2 (ru) 2008-04-25 2008-04-25 Жидкий состав для деферипрона с приятным вкусом

Country Status (24)

Country Link
US (1) US8703156B2 (ru)
EP (1) EP2268282B1 (ru)
KR (1) KR101490721B1 (ru)
CN (1) CN102014904B (ru)
AP (1) AP2010005454A0 (ru)
AU (1) AU2008355464C1 (ru)
BR (1) BRPI0822206B8 (ru)
CA (1) CA2722393A1 (ru)
CR (1) CR11744A (ru)
CY (1) CY1116146T1 (ru)
DK (1) DK2268282T3 (ru)
EA (1) EA022751B1 (ru)
ES (1) ES2539414T3 (ru)
HR (1) HRP20150083T1 (ru)
IL (1) IL208876A (ru)
MX (1) MX2010011701A (ru)
NZ (1) NZ588602A (ru)
PL (1) PL2268282T3 (ru)
PT (1) PT2268282E (ru)
RS (1) RS53689B1 (ru)
SI (1) SI2268282T1 (ru)
UA (1) UA102254C2 (ru)
WO (1) WO2009129592A1 (ru)
ZA (1) ZA201008374B (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2246044A1 (en) * 2009-04-21 2010-11-03 Pierre Fabre Dermo-Cosmétique Paediatric solutions comprising a beta-blocker
SG177462A1 (en) 2009-07-03 2012-02-28 Apotex Technologies Inc Fluorinated derivatives of 3-hydroxypyridin-4-ones
US20150246027A1 (en) 2012-11-12 2015-09-03 Cipla Limited Fixed dose pharmaceutical composition comprising deferasirox and deferiprone
WO2017199073A1 (en) * 2016-05-18 2017-11-23 Karimian, Khashayar Effervescent deferiprone tabelt
GR1009462B (el) * 2017-10-05 2019-02-15 Laboserve Φαρμακευτικη Βιομηχανια Α.Ε. Ποσιμο φαρμακευτικο διαλυμα με συγκαλυμμενη γευση
MY204588A (en) 2017-10-25 2024-09-05 Chiesi Farm Spa Delayed release deferiprone tablets and methods of using the same
CN113543652B (zh) * 2019-03-14 2024-07-05 神经活力投资公司 用于酮体化合物的掩味制剂
US12053447B2 (en) 2019-06-25 2024-08-06 NuBioPharma, LLC Oral solution and powder to liquid compositions of balsalazide
NL2024161B1 (en) * 2019-11-05 2021-07-20 Mperium B V Pharmaceutical liquid composition, kit of parts comprising the pharmaceutical liquid composition, and method for preparing the pharmaceutical liquid composition
US12016851B2 (en) 2022-04-11 2024-06-25 Chiesi Farmaceutici S.P.A. Modified release pharmaceutical formulations comprising deferiprone
US12016850B2 (en) 2022-04-11 2024-06-25 Chiesi Farmaceutici S.P.A. Modified release pharmaceutical formulations comprising deferiprone
MA71627A (fr) 2022-07-29 2025-05-30 Drotastar Llc Formulation pharmaceutique liquide orale stable d'un agent antispasmodique

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2918402A (en) * 1958-07-29 1959-12-22 Dodge Chem Co Bactericidal-fungicidal compositions
BE639493A (ru) * 1962-12-20
CA1095921A (en) 1976-08-02 1981-02-17 Thomas M. Brennan Preparation of gamma-pyrones
GB8308055D0 (en) 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
GB8308054D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
USRE34313E (en) * 1983-09-23 1993-07-13 National Research Development Corporation Pharmaceutical compositions
GB8325496D0 (en) 1983-09-23 1983-10-26 Hider R C Pharmaceutical compositions
GB8329043D0 (en) 1983-10-31 1983-11-30 Hider R C Pharmaceutical compositions
EP0336369A1 (en) 1988-04-04 1989-10-11 E.R. Squibb & Sons, Inc. 3-Acylamino-1-[[[(substituted sulfonyl)amino]carbonyl]amino]2-azetidinones
DE3826846A1 (de) 1988-08-06 1990-02-08 Goedecke Ag Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
JPH0714872B2 (ja) * 1990-02-06 1995-02-22 昭和薬品化工株式会社 シロップ剤組成物
GB9100465D0 (en) 1991-01-09 1991-02-20 Hider Robert C Pharmaceutical compositions
US5624807A (en) * 1992-07-22 1997-04-29 The Mclean Hospital Corporation Methods for detecting Alzheimer's disease by measuring ratios of calcium-activated neutral protease isoforms
FI941777A7 (fi) * 1993-04-16 1994-10-17 Mcneil Ppc Inc Vesipitoinen farmaseuttinen suspensio ja menetelmä sen valmistamiseksi
EP0741717A1 (en) 1994-01-31 1996-11-13 Cultor Ltd. Method of synthesizing gamma pyrones
WO1995027485A1 (en) * 1994-04-08 1995-10-19 The Procter & Gamble Company Methods of using iron chelating compounds to reduce free radical damage in mammals
AU3154895A (en) * 1994-08-01 1996-03-04 Kv Pharmaceutical Corporation Tastemasked liquid pharmaceutical delivery system
US5616621A (en) * 1995-01-30 1997-04-01 American Home Products Corporation Taste masking liquids
JPH0925234A (ja) 1995-07-12 1997-01-28 Wakunaga Pharmaceut Co Ltd 脳疾患改善剤
US5763449A (en) * 1996-08-07 1998-06-09 Ascent Pediatrics, Inc. Pleasant-tasting aqueous liquid composition of a bitter-tasting drug
GB9711093D0 (en) * 1997-05-29 1997-07-23 British Tech Group Novel orally active iron (III) chelators
WO2000012135A1 (fr) 1998-08-28 2000-03-09 Eisai Co., Ltd Compositions medicales presentant une amertume, etc., reduite
US6472378B2 (en) * 1998-08-31 2002-10-29 Pro-Neuron, Inc. Compositions and methods for treatment of mitochondrial diseases
US6133322A (en) * 1998-10-29 2000-10-17 Institut National De La Sante Et De La Recherche Medicale (Inserm) Quinone derivatives for treating or preventing diseases associated with iron overload
US6933104B1 (en) * 1999-04-23 2005-08-23 Shiva Biomedical, Llc Diagnosis and treatment of human kidney diseases
IL130324A0 (en) * 1999-06-07 2000-06-01 Yeda Res & Dev Pharmaceutical compositions comprising iron chelators for the treatment of neurodegenerative disorders and some novel iron chelators
AUPQ262499A0 (en) 1999-09-02 1999-09-23 University Of Queensland, The Novel iron chelators
CA2313270C (en) 2000-06-30 2011-09-13 Apotex Inc. Use of deferiprone in treating and preventing iron-induced cardiac disease
JP2004535370A (ja) * 2001-03-05 2004-11-25 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 味をマスクした液体製薬学的組成物
AU2003222513A1 (en) 2002-03-08 2003-09-22 Protemix Corporation Limited Preventing and/or treating vascular disease, cardiomyopathy and/or associated heart failure
CN100337630C (zh) * 2002-03-12 2007-09-19 布里斯托尔-迈尔斯斯奎布公司 可口的口服悬浮液及其制备方法
WO2004006856A2 (en) * 2002-07-12 2004-01-22 The Buck Institute For Research On Aging Iron sequestration or elimination to reduce neurodegeneration or parkinsons disease progression
JP4757024B2 (ja) * 2002-11-07 2011-08-24 テクニオン リサーチ アンド ディベラップメント ファウンデイション リミテッド 神経保護鉄キレート剤及びそれを含む医薬組成物
DE10336497B4 (de) 2003-08-08 2007-04-05 Freie Universität Berlin Substituierte Pyridine und ein Verfahren zur Herstellung von substituierten Pyridinen
US20050250738A1 (en) * 2004-05-06 2005-11-10 Mosher Gerold L Taste-masked formulations containing sertraline and sulfoalkyl ether cyclodextrin
JP2008500347A (ja) * 2004-05-24 2008-01-10 ニュー・ヨーク・ユニヴァーシティー 高血糖症による血糖の急激な増加及び／又は急激な遊離脂肪酸流動の増加の病理学的影響の治療方法又は予防方法
US9737511B2 (en) * 2004-05-24 2017-08-22 Geoffrey C. GURTNER Method of treating or preventing pathologic effects of acute increases in hyperglycemia and/or acute increases of free fatty acid flux
US7728038B2 (en) * 2004-08-04 2010-06-01 University Of Utah Research Foundation Methods for chelation therapy
US20060093630A1 (en) * 2004-10-29 2006-05-04 Buehler Gail K Dye-free pharmaceutical suspensions and related methods
US20070197469A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V Fluoroquinolone carboxylic acid salt compositions
CN101420954A (zh) 2006-02-22 2009-04-29 阿诺德·明尼希 去铁酮的用途以及治疗和/或预防由细胞内铁的处理不当引起的弗里德赖希共济失调的方法
EP2134688B1 (en) * 2007-03-28 2016-10-05 Apotex Technologies Inc. Fluorinated derivatives of deferiprone
GB0803019D0 (en) 2008-02-19 2008-03-26 Btg Int Ltd Fluorinated compounds

Also Published As

Publication number Publication date
AU2008355464C1 (en) 2014-11-20
US20110039897A1 (en) 2011-02-17
ES2539414T3 (es) 2015-06-30
CN102014904B (zh) 2013-02-06
RS53689B1 (en) 2015-04-30
SI2268282T1 (sl) 2015-01-30
EP2268282A1 (en) 2011-01-05
DK2268282T3 (en) 2014-11-24
CY1116146T1 (el) 2017-02-08
CA2722393A1 (en) 2009-10-29
MX2010011701A (es) 2010-12-06
AU2008355464A1 (en) 2009-10-29
PT2268282E (pt) 2015-02-05
AU2008355464B2 (en) 2014-04-10
PL2268282T3 (pl) 2015-04-30
KR20100135316A (ko) 2010-12-24
HRP20150083T1 (hr) 2015-03-13
WO2009129592A1 (en) 2009-10-29
BRPI0822206B8 (pt) 2021-05-25
KR101490721B1 (ko) 2015-02-06
BRPI0822206A2 (pt) 2015-06-23
HK1152871A1 (en) 2012-03-16
EA022751B1 (ru) 2016-02-29
ZA201008374B (en) 2012-01-25
BRPI0822206B1 (pt) 2019-03-19
CR11744A (es) 2011-01-10
EP2268282A4 (en) 2011-06-22
AP2010005454A0 (en) 2010-12-31
IL208876A0 (en) 2011-01-31
EA201071235A1 (ru) 2011-06-30
CN102014904A (zh) 2011-04-13
NZ588602A (en) 2012-08-31
US8703156B2 (en) 2014-04-22
IL208876A (en) 2015-02-26
EP2268282B1 (en) 2014-10-29

Similar Documents

Publication Publication Date Title
UA102254C2 (ru) Жидкий состав для деферипрона с приятным вкусом
UA103906C2 (ru) Жидкая фармацевтическая композиция, которая содержит парацетамол
MX2009000722A (es) Composiciones liquidas de acetato de calcio.
MY147994A (en) Azabiphenylaminobenzoic acid derivatives as dhodh inhibitors
TW200716202A (en) Pediatric formulation of topiramate
SG171649A1 (en) Dpp iv inhibitor formulations
WO2007098128A3 (en) Phenylephrine-containing liquid formulations
WO2006099941A8 (de) Aminocarbonyl substituierte 8-n-benzimidazole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
MX2010003923A (es) Formulacion farmaceutica de valsartan.
WO2011017502A3 (en) Linaclotide-containing formulations for oral administration
WO2010021607A3 (en) Pharmaceutical formulation
WO2008042944A3 (en) Non-irritating oral care formulations
PT2459153E (pt) Composição farmacêutica ou cosmética ou dietética tendo o efeito de favorecer a pigmentação capilar
WO2010090494A3 (ko) 5-벤질아미노살리실산 유도체 또는 이의 염의 의약 용도
WO2009064681A3 (en) Liquid compositions comprising valsartan
WO2011011351A3 (en) A stable pharmaceutical omeprazole formulation for oral administration
WO2011076209A3 (en) Pharmaceutical composition comprising solvent mixture and a vitamin d derivative or analogue
WO2007146293A3 (en) Improved composition and method for taste masking
WO2008074833A3 (en) Compounds
MA32406B1 (fr) Composés contenant de l'azote tricyclique et utilisation de ceux-ci comme antibactériens
UA96794C2 (ru) Глюкокортикоиды, способ их применения, способ лечения и фармацевтическая композиция на их основе
WO2009142428A3 (en) Pharmaceutical composition for the treatment of premature ejaculation
WO2004091591A3 (fr) Composition nutritionnelle ou therapeutique contenant le compose oleurofeine ou l'un de ses derives
WO2010121213A3 (en) Antibacterial compositions
WO2006060681A3 (en) Pharmaceutical composition containing an anti-nucleating agent