US20030013683A1 - Method of treating body insect infestation - Google Patents
Method of treating body insect infestation Download PDFInfo
- Publication number
- US20030013683A1 US20030013683A1 US10/232,472 US23247202A US2003013683A1 US 20030013683 A1 US20030013683 A1 US 20030013683A1 US 23247202 A US23247202 A US 23247202A US 2003013683 A1 US2003013683 A1 US 2003013683A1
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- Prior art keywords
- lice
- silicone
- shampoo
- treatment
- minutes
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 241000238631 Hexapoda Species 0.000 title claims abstract description 21
- 238000000034 method Methods 0.000 title claims abstract description 11
- 206010061217 Infestation Diseases 0.000 title claims description 13
- 241001674048 Phthiraptera Species 0.000 claims abstract description 34
- 239000000314 lubricant Substances 0.000 claims abstract description 16
- 241000238876 Acari Species 0.000 claims abstract description 14
- 208000028454 lice infestation Diseases 0.000 claims description 16
- 238000011282 treatment Methods 0.000 claims description 13
- 241000517307 Pediculus humanus Species 0.000 claims description 11
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims description 8
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 8
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 8
- 241000517324 Pediculidae Species 0.000 claims description 3
- 241000517305 Pthiridae Species 0.000 claims description 2
- 241001465754 Metazoa Species 0.000 claims 1
- 241000258242 Siphonaptera Species 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 description 42
- 239000002453 shampoo Substances 0.000 description 22
- 238000002474 experimental method Methods 0.000 description 12
- 239000003921 oil Substances 0.000 description 12
- 235000019198 oils Nutrition 0.000 description 12
- 238000012360 testing method Methods 0.000 description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 150000001875 compounds Chemical class 0.000 description 6
- -1 pyrethrun Chemical compound 0.000 description 6
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- 229940057995 liquid paraffin Drugs 0.000 description 4
- 239000002480 mineral oil Substances 0.000 description 4
- 235000010446 mineral oil Nutrition 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000004006 olive oil Substances 0.000 description 3
- 235000008390 olive oil Nutrition 0.000 description 3
- 229920002367 Polyisobutene Polymers 0.000 description 2
- 239000003225 biodiesel Substances 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000000446 fuel Substances 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 235000010746 mayonnaise Nutrition 0.000 description 2
- 239000008268 mayonnaise Substances 0.000 description 2
- 239000010702 perfluoropolyether Substances 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 241000238682 Amblyomma americanum Species 0.000 description 1
- 241001480824 Dermacentor Species 0.000 description 1
- 229920004511 Dow Corning® 200 Fluid Polymers 0.000 description 1
- 239000005949 Malathion Substances 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- 235000019486 Sunflower oil Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- 239000002283 diesel fuel Substances 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- JXSJBGJIGXNWCI-UHFFFAOYSA-N diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate Chemical compound CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC JXSJBGJIGXNWCI-UHFFFAOYSA-N 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
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- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- JLYXXMFPNIAWKQ-GNIYUCBRSA-N gamma-hexachlorocyclohexane Chemical compound Cl[C@H]1[C@H](Cl)[C@@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H]1Cl JLYXXMFPNIAWKQ-GNIYUCBRSA-N 0.000 description 1
- JLYXXMFPNIAWKQ-UHFFFAOYSA-N gamma-hexachlorocyclohexane Natural products ClC1C(Cl)C(Cl)C(Cl)C(Cl)C1Cl JLYXXMFPNIAWKQ-UHFFFAOYSA-N 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 229960002809 lindane Drugs 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 229960000453 malathion Drugs 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000002969 morbid Effects 0.000 description 1
- 230000001473 noxious effect Effects 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 239000003090 pesticide formulation Substances 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N61/00—Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
Definitions
- This invention relates to the safe and effective treatment of lice, nits (and other infestational insects) by using low surface tension lubricants.
- the invention compromises the direct treatment of body insect infestation with a synthetic lubricant, such as food grade silicon, to effectively kill infesting insects such as lice, and nits, as well as fleas, ticks and other insects.
- a synthetic lubricant such as food grade silicon
- the synthetic lubricant is applied directly to the insects, or is provided as a major (more than 50 volume percent) of a shampoo formulation. If added to a shampoo, the exact effective concentration level above 50% is determined based on both the nature of the synthetic lubricant, and the nature of the shampoo used.
- Silicone was directly applied to the hair of three school children, each of which had been infested with lice and nits. Each of the children applied the silicone directly to his or her hair and left it on for five minutes. After five minutes, the hair was washed first with Prell® shampoo and then with Johnson's Baby Shampoo®. In all three cases the infestation was successfully ended with one application.
- the preferred embodiment for use as a head lice treatment is to use the Silicone in its pure state, that is Dow Coming 200 fluid, 350 CST. Which is a silicone fluid termed Dimethyl polysiloxane.
- the Silicone is water white and has a consistency of light syrup. This form is preferred as it clings easily to the hair.
- the Silicone is applied to the entire head, left on for at least ten minutes, and then washed off with any standard shampoo. Within a short time after application of the shampoo, the area is free of any live lice. Any nits do not mature.
- Other embodiments include the processing of synthetic lubricants into a shampoo that effectively kills ticks, fleas, and other insects.
- concentration of such lubricants, and the amount of time they must remain on the affected area is above 50% by volume and is adjusted depending on the type of insect being treated.
- the ticks took longer to die than the lice did in the prior experiments using pure Silicone treatment.
- ten Amblyomma Americanum ticks were coated with Silicone, and ten were coated with Prell® Shampoo. After ten minutes, both sets of ticks were washed with water and Prell® Shampoo for five minutes, until all of the Silicone and shampoo were removed.
- Silicone and more particularly Dimethylpolysiloxane (or Polydimethylsiloxane) has a far lower surface tension than other oils.
- Surface tension is a measure of the stretching force required to form a liquid film, and is equal to the surface energy of the liquid per unit length of the film at equilibrium: the force tends to minimize the area of a surface. Surface tension is caused by the attraction of molecules to each other.
- the surface tension of polydimethylsiloxane at about 20.9 dynes/cm is about 50% lower than the surface tension of most natural oils and is believed to account for its greater ability to penetrate and induce morbidity in insects.
- Krytox® 1514 a fluorinated oil PerFluoroPolyEther (PFPE), with a surface tension of 18, we found that it was also effective in killing lice but slightly less effective than Dow Coming 200 fluid, 350 CST .
- the greater effectiveness of the Dow Corning 350 CST material is very likely due to the its greater viscosity.
- Viscosity or kinematic viscosity is measured in stokes, and is defined to be the dynamic viscosity divided by the density of the liquid; this gives a quantity which depends only on the type of the liquid. independent of its concentration or density.
- Krytox1514 has a viscosity of 142 centistokes (cst)
- Dow Corning 200 fluid, 350 CST has a viscosity of 350 cst. The viscosity adds to the effectiveness by creating better adhesion of the lubricant to the insects.
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Described is a safe and effective method for treating lice and nits (fleas, ticks and other insects) with a low surface tension lubricant.
Description
- This invention relates to the safe and effective treatment of lice, nits (and other infestational insects) by using low surface tension lubricants.
- For centuries, people have been plagued by head lice, body lice, and pubic lice, which appear in numerous species all having similar physiological characteristics. Over the years, people have expended tremendous efforts and resources to develop a safe and effective method for eliminating the problem of lice and nits. To date, the only patented processes for killing lice and nits involve the use of poisons, pesticides or noxious soaps with numerous side effects and cautionary uses. These pediculicides, such as lindane, pyrethrun, or malathion, are not optimal for the treatment of lice or nits because they are not healthful, and because, over time, lice tend to develop a natural resistance to poison or pesticide formulation.
- It is accordingly an object of the present invention to provide a method and chemical formulation for effective yet safe treatment for body insect infestation such as lice, fleas, and the like.
- Generally present the invention compromises the direct treatment of body insect infestation with a synthetic lubricant, such as food grade silicon, to effectively kill infesting insects such as lice, and nits, as well as fleas, ticks and other insects. In Accordance with the present invention, the synthetic lubricant is applied directly to the insects, or is provided as a major (more than 50 volume percent) of a shampoo formulation. If added to a shampoo, the exact effective concentration level above 50% is determined based on both the nature of the synthetic lubricant, and the nature of the shampoo used.
- In order to illustrate the efficacy of the present invention the following test examples are presented.
- Two tests were conducted using a compound containing 60% silicone-based oil. In the first test the compound was placed on a louse on a paper towel. After 5 minutes, the louse washed off with Prell® shampoo and water. The louse was observed one minute later and was dead. In the second test using the same compound, the compound was applied to the long, thick hair of a school girl, which had been infested with lice for several months. After five minutes, the compound was removed by several washes with Prell® shampoo, with the compound being otherwise difficult to extract from the hair. The infestation was successfully treated and no lice or nits returned.
- Additional tests were conducted using a 100% concentration of Dow corning Fluid Food Grade silicone (350 CST) (the “silicone”). These tests also revealed that, in addition to killing lice, the silicone was effective at preventing nits from maturing. In these tests, silicone was applied directly to head lice, body lice, and to the hair of several children infested with head lice.
- In the first Silicone experiment three head lice were collected from school children. The lice were placed on the hand of a subject and they attached themselves to the hair on the subject's hand. After five minutes, the lice were gently washed off with Prell® shampoo and then water.
- Although there appeared to be mortality within minutes, the lice were left on the hand for further examination (they were covered with a loosely fitting bandage to make sure they did not fall off). During the following six hours, the lice were checked periodically and all were found to be dead.
- In a further Silicone experiment, Silicone was directly applied to the hair of three school children, each of which had been infested with lice and nits. Each of the children applied the silicone directly to his or her hair and left it on for five minutes. After five minutes, the hair was washed first with Prell® shampoo and then with Johnson's Baby Shampoo®. In all three cases the infestation was successfully ended with one application.
- In a continuing experiment, Silicone was directly applied to the hair of twenty school children, each of which had been infested with lice and nits. Each of the children applied the silicone directly to his or her hair and left it on for ten minutes minutes. After ten minutes, the hair was washed with a shampoo of the parent's choice. In all twenty cases the infestation was successfully ended with one application.
- In another experiment ten adult lice were immersed in the Silicone for ten minutes, then washed and rinsed for one minute each in water. A set of ten control lice were immersed in water for ten minutes and then also washed and rinsed for one minute. The lice were then held in an incubator. A review of the lice after one hour, and again after twenty-four hours, revealed a 100% morality of those who had been immersed in Silicone. There was no morality among the controls.
- In an additional experiment, ten adult lice were immersed in the Silicone for ten minutes, and subsequently washed in a dilution of 50:50 Johnson's Baby Shampoo® and tap water. To test the effectiveness at different concentrations of Silicone, four mixtures were made using the Silicone with Johnson's Baby Shampoo® with the following concentrations:
- a. 100% Johnson's Baby Shampoo
- b. 3% Silicone and 97% Johnson's Baby Shampoo
- c. 15% Silicone and 85% Johnson's Baby Shampoo
- d. 40% Silicone and 60% Johnson's Baby Shampoo
- e. Control with water
- The results of the test after 24 hours were that for samples a and c, one louse was dead; for samples b and e, no lice were dead. The one louse being dead was considered not statistically significant. In sample d, containing 40% Silicone, four lice were dead, indicating that at this concentration there is some effectiveness of the Silicone in killing lice but not a fully useful concentration. It is believed that other ingredients may interfere with the effectiveness of the Silicone, and accordingly it is preferred to use the Silicone in a high concentration or in a pure state.
- In another experiment to determine the effect of lubricants of various surface tensions, a test was done using 10 adult lice immersing them into one of three solutions for ten minutes and then washing them of with a soapy water solution. The three lubricants used were Johnson's baby oil a mineral oil, Ultra pure lamp oil 99% pure liquid paraffin, and Krytox® 1514 Vacuum pump fluid, produced by Dupont®. The lice were then observed after one hour, and three hours and the amount dead were the same at both intervals in all tests. The mortality rate was highest for the Krytox® 1514 with nine of ten dead within one hour, lowest for the liquid paraffin with three of ten dead within one hour, and moderate for the mineral oil with four of ten dead within one hour. In a repeat of the experiment for the Krytox, seven out of ten where dead within one hour, for liquid paraffin two out of ten, and for mineral oil five out of ten.
- The preferred embodiment for use as a head lice treatment is to use the Silicone in its pure state, that is Dow Coming 200 fluid, 350 CST. Which is a silicone fluid termed Dimethyl polysiloxane. The Silicone is water white and has a consistency of light syrup. This form is preferred as it clings easily to the hair. The Silicone is applied to the entire head, left on for at least ten minutes, and then washed off with any standard shampoo. Within a short time after application of the shampoo, the area is free of any live lice. Any nits do not mature.
- Other embodiments include the processing of synthetic lubricants into a shampoo that effectively kills ticks, fleas, and other insects. The concentration of such lubricants, and the amount of time they must remain on the affected area, is above 50% by volume and is adjusted depending on the type of insect being treated. Thus, for example, in two experiments conducted on ticks, the ticks took longer to die than the lice did in the prior experiments using pure Silicone treatment. In the first tick experiment, ten Amblyomma Americanum ticks were coated with Silicone, and ten were coated with Prell® Shampoo. After ten minutes, both sets of ticks were washed with water and Prell® Shampoo for five minutes, until all of the Silicone and shampoo were removed. While all of the “Silicone” ticks were alive after one hour, after six hours three of the ticks were dead, five were morbid, and two were alive. After twenty-four hours, all of the “Silicone” ticks were dead, whereas only two of the “Prell®” ticks were dead.
- In a second tick experiment, ten Dermacentor Varibilis ticks were coated with Silicone. After ten minutes all of the ticks were still alive. After ninety minutes, all of the ticks were dead.
- While Silicone has been used for many years as a hair-bodying agent, and there are many patents (U.S. Pat. No. 3,964,500, U.S. Pat. No. 4,427,557, U.S. Pat. No. 4,465,619, U.S. Pat. No. 4,704,272, U.S. Pat. No. 5,728,457, U.S. Pat. No. 4,749,732, U.S. Pat. No. 4,842,850, U.S. Pat. No. 5,015,415, U.S. Pat. No. 5,034,218, U.S. Pat. No. 5,063,044, U.S. Pat. No. 4,902,499, U.S. Pat. No. 4,906,459, U.S. Pat. No. 5,554,313, U.S. Pat. No. 577,644) that focus on using silicone, and some specifically polysiloxanes, for various benefits to the hair. Such use levels have always been at concentrations below 50% wherein effectiveness for insect control was not evident. For actual effectiveness use in the range of 50-100% concentration is required.
- It is believed that the lubricating properties of the silicone provide a morbidity passageway for interfering with insect respiratory and possibly digestive functions, and accordingly other similar lubricants and Silicone derivatives are effective in such insect control.
- With regard to head lice, the point of entry where the silicone permeates the head lice is very likely the thoracic spiracle, the honeycomb structure which creates maximum surface area and efficient exchange of air and moisture. The nits are likely affected via the head louse nit operculum which contain doughnut shaped holes. See Meinking, T. L.Current Problems in Dermatology 11 (3) pp 73-120 May/June 1999.
- With regard to head lice many natural oils treatments have been attempted but with limited efficacy. In a school based study to evaluate alternative treatments, children with head lice were treated with olive oil, mayonnaise, or Vasoline® petroleum jelly overnight under a shower cap. They came to school the next day with their greasy hair still covered by shower caps. After a shampoo rinse, the lice from heads treated with olive oil or mayonnaise were found to still be alive. The children who used Vasoline® had many dead nymphs stuck to the scalp or hair but some adult lice were still alive. See Meinking, T. L., ibid.
- The efficacy of silicone based lubricants over other oils appears to be related to the lubricity of silicone. Silicone and more particularly Dimethylpolysiloxane (or Polydimethylsiloxane) has a far lower surface tension than other oils. Surface tension is a measure of the stretching force required to form a liquid film, and is equal to the surface energy of the liquid per unit length of the film at equilibrium: the force tends to minimize the area of a surface. Surface tension is caused by the attraction of molecules to each other.
- Below is a list of the surface tension of a variety of polymers and oils at 20° C.
Polymer/oil system Surface Tension (dynes/cm) Polydimethylsiloxane (PDMS) 20.91 Polyisobutylene (PIB) 35.61 n-alkanes 37.81 n-fluoroalkanes 25.91 diesel fuel 252 deodorized sunflower oil 332 crude soybean oil 322 refined soybean oil 322 cottonseed oil 35.43 coconut oil 33.43 olive oil 33.03 corn oil 33.44 peanut oil 35.54 mineral oil (MWP paraffin) 28.84 mineral oil-baby oil 30.85 liquid paraffin 26-285 Krytox 1514 186 - The surface tension of polydimethylsiloxane at about 20.9 dynes/cm is about 50% lower than the surface tension of most natural oils and is believed to account for its greater ability to penetrate and induce morbidity in insects. In our experiment with Krytox® 1514 a fluorinated oil PerFluoroPolyEther (PFPE), with a surface tension of 18, we found that it was also effective in killing lice but slightly less effective than Dow Coming 200 fluid, 350 CST . The greater effectiveness of the Dow Corning 350 CST material is very likely due to the its greater viscosity. Viscosity , or kinematic viscosity is measured in stokes, and is defined to be the dynamic viscosity divided by the density of the liquid; this gives a quantity which depends only on the type of the liquid. independent of its concentration or density. Krytox1514 has a viscosity of 142 centistokes (cst), while Dow Corning 200 fluid, 350 CST has a viscosity of 350 cst. The viscosity adds to the effectiveness by creating better adhesion of the lubricant to the insects.
- Attempts have been made to modify vegetable oils thru processes such as transesterification in order to lower their surface tensions and thus make them usable as biodiesel fuels. See Cecil, A. W.; Allen, K.; Watts. C. and Ackman R. G. in “Predicting the Surface Tension of Biodiesel Fuels from Their Fatty Acid Composition”,JAOCS 76(3), pp. 317-323 (March ,1999). It is probable that if vegetable or other oils were processed to lower their surface tension close to the surface tension found in polydimethylsiloxane i.e. less than about 25 dynes/centimeter, it would have the same effect on the lice.
Claims (5)
1. A method of treatment of body insect infestation comprising the step of topically applying a lubricant with a surface tension below about 25 dynes/centimeter (at 20° C.) to the body insect infestation and allowing the lubricant to remain on the insect infestation for a time sufficient to allow for complete killing of all insects.
2. A method of treatment of body insect infestation where the lubricant claimed in claim 1 , has a viscosity above about 200 centistokes (at 20° C.).
3. A method of treatment of body insect infestation as claimed in claim 1 where the lubricant comprises dimethylpolysiloxane.
4. A method of treatment as claimed in claim 1 where the infestation is any form of pediculosis including head, body or pubic lice.
5. A method of treatment as claimed in claim 1 where the infestation are lice, ticks and fleas in animals.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/232,472 US20030013683A1 (en) | 1999-08-19 | 2002-08-30 | Method of treating body insect infestation |
US10/889,717 US20040242541A1 (en) | 1999-08-19 | 2004-07-12 | Method of treating body insect infestation |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14947199P | 1999-08-19 | 1999-08-19 | |
US09/937,627 US6683065B1 (en) | 1999-08-19 | 2000-08-17 | Method of treating body insect infestation |
US10/232,472 US20030013683A1 (en) | 1999-08-19 | 2002-08-30 | Method of treating body insect infestation |
Related Parent Applications (2)
Application Number | Title | Priority Date | Filing Date |
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US09/937,627 Continuation US6683065B1 (en) | 1999-08-19 | 2000-08-17 | Method of treating body insect infestation |
PCT/US2000/022577 Continuation WO2001013954A1 (en) | 1999-08-19 | 2000-08-17 | Method of treating body insect infestation |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
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US10/889,717 Continuation US20040242541A1 (en) | 1999-08-19 | 2004-07-12 | Method of treating body insect infestation |
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US20030013683A1 true US20030013683A1 (en) | 2003-01-16 |
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Application Number | Title | Priority Date | Filing Date |
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US09/937,627 Expired - Lifetime US6683065B1 (en) | 1999-08-19 | 2000-08-17 | Method of treating body insect infestation |
US10/232,472 Abandoned US20030013683A1 (en) | 1999-08-19 | 2002-08-30 | Method of treating body insect infestation |
US10/889,717 Abandoned US20040242541A1 (en) | 1999-08-19 | 2004-07-12 | Method of treating body insect infestation |
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US09/937,627 Expired - Lifetime US6683065B1 (en) | 1999-08-19 | 2000-08-17 | Method of treating body insect infestation |
Family Applications After (1)
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US10/889,717 Abandoned US20040242541A1 (en) | 1999-08-19 | 2004-07-12 | Method of treating body insect infestation |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070266749A1 (en) * | 2006-05-15 | 2007-11-22 | Jason Rader | Pesticidal compositions for treating anthropods and methods for the use thereof |
US20080221223A1 (en) * | 2006-05-15 | 2008-09-11 | Oms Investments Inc. | Methods for treating arthropods |
WO2009105617A1 (en) * | 2008-02-22 | 2009-08-27 | Host Pharmaceuticals, Llc | Method of treating body insect infestation |
US20140073605A1 (en) * | 2012-09-13 | 2014-03-13 | Maria Beug-Deeb Inc. Dba T&M Associates | Method for the removal and control of arthropod infestation in interior dwellings |
US8734821B2 (en) | 2006-05-15 | 2014-05-27 | Oms Investments, Inc. | Silicone surfactant-based agricultural formulations and methods for the use thereof |
US20150258006A1 (en) * | 2012-11-30 | 2015-09-17 | Henkel Ag & Co. Kgaa | Three-phase hair conditioner |
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US6683065B1 (en) * | 1999-08-19 | 2004-01-27 | Host Pharmaceuticals Llc | Method of treating body insect infestation |
US20080137670A1 (en) * | 2005-06-09 | 2008-06-12 | Whirlpool Corporation | Network System with Message Binding for Appliances |
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US7604814B2 (en) * | 2006-08-29 | 2009-10-20 | Karykion Inc. | Method of removing ticks from the epidermal tissue of humans and other mammals |
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GB2470208B (en) | 2009-05-14 | 2014-01-29 | Thornton & Ross Ltd | A method and composition for the control of ectoparasites |
DE102009034704A1 (en) * | 2009-07-24 | 2011-01-27 | G. Pohl-Boskamp Gmbh & Co. Kg | Agent for combating ectoparasites |
US8844193B2 (en) * | 2010-10-19 | 2014-09-30 | Joseph Luongo | Apparatus for killing and removing ticks |
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US6663876B2 (en) * | 2002-04-29 | 2003-12-16 | Piedmont Pharmaceuticals, Llc | Methods and compositions for treating ectoparasite infestation |
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- 2000-08-17 US US09/937,627 patent/US6683065B1/en not_active Expired - Lifetime
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US4155995A (en) * | 1973-03-23 | 1979-05-22 | Witco Chemical Corporation | Petroleum based mosquito larvicide |
US4146619A (en) * | 1977-05-31 | 1979-03-27 | Block Drug Company Inc. | Siloxane toxicants |
US5045536A (en) * | 1986-06-07 | 1991-09-03 | Baker Ivor P | Liquid formulations |
US5288483A (en) * | 1990-04-18 | 1994-02-22 | The Procter & Gamble Company | Anti-lice treatment compositions |
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Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070266749A1 (en) * | 2006-05-15 | 2007-11-22 | Jason Rader | Pesticidal compositions for treating anthropods and methods for the use thereof |
US20080221223A1 (en) * | 2006-05-15 | 2008-09-11 | Oms Investments Inc. | Methods for treating arthropods |
US8734821B2 (en) | 2006-05-15 | 2014-05-27 | Oms Investments, Inc. | Silicone surfactant-based agricultural formulations and methods for the use thereof |
US8790673B2 (en) | 2006-05-15 | 2014-07-29 | Oms Investments, Inc. | Methods for treating arthropods |
US10299481B2 (en) | 2006-05-15 | 2019-05-28 | Oms Investments, Inc. | Methods for treating arthropods |
US12349678B2 (en) | 2006-05-15 | 2025-07-08 | Oms Investments, Inc. | Methods for treating arthropods |
WO2009105617A1 (en) * | 2008-02-22 | 2009-08-27 | Host Pharmaceuticals, Llc | Method of treating body insect infestation |
US8097602B1 (en) | 2008-02-22 | 2012-01-17 | Host Pharmaceuticals, Llc | Method of treating body insect infestation |
US20140073605A1 (en) * | 2012-09-13 | 2014-03-13 | Maria Beug-Deeb Inc. Dba T&M Associates | Method for the removal and control of arthropod infestation in interior dwellings |
US10015969B2 (en) * | 2012-09-13 | 2018-07-10 | Maria Beug-Deeb | Method for the removal and control of arthropod infestation in interior dwellings |
US20150258006A1 (en) * | 2012-11-30 | 2015-09-17 | Henkel Ag & Co. Kgaa | Three-phase hair conditioner |
Also Published As
Publication number | Publication date |
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US6683065B1 (en) | 2004-01-27 |
US20040242541A1 (en) | 2004-12-02 |
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Owner name: HOST PHARMACEUTICALS, LLC, NEW JERSEY Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:HOLZER, DAVID;REEL/FRAME:013773/0575 Effective date: 20030203 |
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