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WO1988002364A3 - Process for the production of ethane derivatives - Google Patents

Process for the production of ethane derivatives Download PDF

Info

Publication number
WO1988002364A3
WO1988002364A3 PCT/EP1987/000517 EP8700517W WO8802364A3 WO 1988002364 A3 WO1988002364 A3 WO 1988002364A3 EP 8700517 W EP8700517 W EP 8700517W WO 8802364 A3 WO8802364 A3 WO 8802364A3
Authority
WO
WIPO (PCT)
Prior art keywords
production
ethane derivatives
formula
derivatives
compound
Prior art date
Application number
PCT/EP1987/000517
Other languages
German (de)
French (fr)
Other versions
WO1988002364A2 (en
Inventor
Andreas Waechtler
Joachim Krause
Detlef Pauluth
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Priority to DE8787906081T priority Critical patent/DE3775921D1/en
Priority to KR1019880700563A priority patent/KR950005771B1/en
Publication of WO1988002364A2 publication Critical patent/WO1988002364A2/en
Publication of WO1988002364A3 publication Critical patent/WO1988002364A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/32—Non-steroidal liquid crystal compounds containing condensed ring systems, i.e. fused, bridged or spiro ring systems
    • C09K19/321—Compounds containing a bicyclo [2,2,2] octane ring
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/34—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
    • C09K19/3441—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom
    • C09K19/3444—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom the heterocyclic ring being a six-membered aromatic ring containing one nitrogen atom, e.g. pyridine
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/34—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
    • C09K19/3441—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom
    • C09K19/345—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom the heterocyclic ring being a six-membered aromatic ring containing two nitrogen atoms
    • C09K19/3458—Uncondensed pyrimidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Pyridine Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A process for the producing ethane derivatives having the formula (II): R1-(A1-Z1)n-A2-CH2CH2-A-Q, in which R1, A1, Z1, n, A2, Q and A have the meaning given in claim 1. A reactive methylene compound is converted with a compound having the formula (I): CH3-A-Q, in the presence of a base.
PCT/EP1987/000517 1986-09-24 1987-09-12 Process for the production of ethane derivatives WO1988002364A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE8787906081T DE3775921D1 (en) 1986-09-24 1987-09-12 METHOD FOR THE PRODUCTION OF ETHAN DERIVATIVES.
KR1019880700563A KR950005771B1 (en) 1986-09-24 1987-09-12 Process for production of ethane derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863632411 DE3632411A1 (en) 1986-09-24 1986-09-24 METHOD FOR PRODUCING ETHAN DERIVATIVES
DEP3632411.6 1986-09-24

Publications (2)

Publication Number Publication Date
WO1988002364A2 WO1988002364A2 (en) 1988-04-07
WO1988002364A3 true WO1988002364A3 (en) 1988-05-19

Family

ID=6310231

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1987/000517 WO1988002364A2 (en) 1986-09-24 1987-09-12 Process for the production of ethane derivatives

Country Status (6)

Country Link
EP (1) EP0283490B1 (en)
JP (1) JPH01500994A (en)
KR (1) KR950005771B1 (en)
DD (1) DD265619A5 (en)
DE (2) DE3632411A1 (en)
WO (1) WO1988002364A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4423098A1 (en) * 1994-07-01 1996-01-04 Hoechst Ag Use of conjugated compounds containing pyrimidine groups as electroluminescent materials
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
JP5791500B2 (en) 2008-05-23 2015-10-07 パンミラ ファーマシューティカルズ，エルエルシー． 5-lipoxygenase activating protein inhibitor
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2121406A (en) * 1982-05-11 1983-12-21 Secr Defence Liquid crystal cyanophenylethanes
WO1985004874A1 (en) * 1984-04-16 1985-11-07 Merck Patent Gmbh Anisotropic compounds and liquid crystal mixtures therewith
EP0205998A1 (en) * 1985-06-10 1986-12-30 Chisso Corporation Cyclohexane derivative and liquid crystal composition containing same
WO1987004158A2 (en) * 1986-01-03 1987-07-16 MERCK Patent Gesellschaft mit beschränkter Haftung Heterocyclic compounds as components of liquid crystal phases

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2121406A (en) * 1982-05-11 1983-12-21 Secr Defence Liquid crystal cyanophenylethanes
WO1985004874A1 (en) * 1984-04-16 1985-11-07 Merck Patent Gmbh Anisotropic compounds and liquid crystal mixtures therewith
EP0205998A1 (en) * 1985-06-10 1986-12-30 Chisso Corporation Cyclohexane derivative and liquid crystal composition containing same
WO1987004158A2 (en) * 1986-01-03 1987-07-16 MERCK Patent Gesellschaft mit beschränkter Haftung Heterocyclic compounds as components of liquid crystal phases

Also Published As

Publication number Publication date
WO1988002364A2 (en) 1988-04-07
EP0283490A1 (en) 1988-09-28
DD265619A5 (en) 1989-03-08
KR880701705A (en) 1988-11-04
DE3632411A1 (en) 1988-04-07
DE3775921D1 (en) 1992-02-20
KR950005771B1 (en) 1995-05-30
JPH01500994A (en) 1989-04-06
EP0283490B1 (en) 1992-01-08

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