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WO1990000179A3 - Nouvelles proteins, adn les codant et leur usage - Google Patents

Nouvelles proteins, adn les codant et leur usage Download PDF

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Publication number
WO1990000179A3
WO1990000179A3 PCT/FR1989/000348 FR8900348W WO9000179A3 WO 1990000179 A3 WO1990000179 A3 WO 1990000179A3 FR 8900348 W FR8900348 W FR 8900348W WO 9000179 A3 WO9000179 A3 WO 9000179A3
Authority
WO
WIPO (PCT)
Prior art keywords
proteins
novel
dna coding
amino
acid sequences
Prior art date
Application number
PCT/FR1989/000348
Other languages
English (en)
Other versions
WO1990000179A2 (fr
Inventor
Armand Tavitian
Veronique Pizon
Pierre Chardin
Original Assignee
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med
Publication of WO1990000179A2 publication Critical patent/WO1990000179A2/fr
Publication of WO1990000179A3 publication Critical patent/WO1990000179A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention a pour objet de nouvelles séquences d'acides aminés contenant l'un au moins des enchaînements d'acides aminés suivants: MREYKLVVL (I), ALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEIL (II), QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPM (III), EDERVVGKEQGQNLARQWCNCAFL (IV), SKINVNEIEYDLVRQINRKTPVEKKKPKKKSCLLL (V), ALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEIL (VII), QFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMI (VIII), EDERVVGKEQGQNLARQWNNCAFL (IX), SKINVNEIFYDLVRQINRKTPVPGKARKKSSCQLL (X), MREYKVVVL (XI), ALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEIL (XII), QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVI (XIII), ESEREVSSSEGRALAEEWGCPFM (XIV), SKTMVDELFAEIVRQMNYAAQPDKDDPCCSACNIQ (XV). Ces séquences d'acides aminés peuvent être utilisées pour le diagnostic in vitro de pathologies liées à des facteurs oncogènes.
PCT/FR1989/000348 1988-07-04 1989-07-04 Nouvelles proteins, adn les codant et leur usage WO1990000179A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8809031A FR2633639B1 (fr) 1988-07-04 1988-07-04 Nouvelles sequences d'acides amines, acides nucleiques codant pour ces sequences d'acides amines et leurs applications, notamment pour le diagnostic, in vitro, de pathologies liees a l'action de facteurs oncogenes
FR88/09031 1988-07-04

Publications (2)

Publication Number Publication Date
WO1990000179A2 WO1990000179A2 (fr) 1990-01-11
WO1990000179A3 true WO1990000179A3 (fr) 1990-03-08

Family

ID=9368043

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1989/000348 WO1990000179A2 (fr) 1988-07-04 1989-07-04 Nouvelles proteins, adn les codant et leur usage

Country Status (4)

Country Link
EP (1) EP0425549A1 (fr)
JP (1) JPH04503054A (fr)
FR (1) FR2633639B1 (fr)
WO (1) WO1990000179A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0496162A3 (en) * 1990-12-24 1993-09-01 Merck & Co. Inc. Peptide inhibitors of ras-gap interaction
US5582995A (en) * 1993-06-11 1996-12-10 The General Hospital Corporation Methods of screening for compounds which inhibit the direct binding of Ras to Raf
JP2001517954A (ja) * 1997-03-21 2001-10-09 ボード・オヴ・リージェンツ，ザ・ユニヴァーシティ・オヴ・テキサス・システム Ｎｏｅｙ２遺伝子組成物およびその使用方法
US5973130A (en) * 1997-04-30 1999-10-26 Incyte Pharmaceuticals, Inc. Ras-like protein

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Annual Review of Biochemistry, Vol. 56, 1987 M. BARBACID: "Ras Genes", pages 779-827 *
Cell, Vol. 44, No. 1, 17 Janvier 1986, Cell Press C.J. DER et al.: "Biological and Biochemical Properties of Human RasH Genes Mutated at Codon 61", pages 167-176 *
Proc. Natl. Acad. Sci. Usa, Vol. 84, Decembre 1987 N. TOUCHOT et al.: "Four Additional Members of the Ras Gene Superfamily Isolated by an Oligonucleotide Strategy: Molecular Cloning of YPT-Related cDNAs from a Rat Brain Library", pages 8210-8214 *
The EMBO Journl, Vol. 5, No. 9, 1986, IRL Press Ltd (Oxford, GB) P. CHARDIN et al.: "The Ral Gene: A New Ras Related Gene Isolated by the use of a Synthetic Probe" pages 2203-2208 *

Also Published As

Publication number Publication date
WO1990000179A2 (fr) 1990-01-11
JPH04503054A (ja) 1992-06-04
FR2633639A1 (fr) 1990-01-05
EP0425549A1 (fr) 1991-05-08
FR2633639B1 (fr) 1991-05-10

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