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WO1992009309A3 - Method of liquid sterilization - Google Patents

Method of liquid sterilization Download PDF

Info

Publication number
WO1992009309A3
WO1992009309A3 PCT/US1991/008900 US9108900W WO9209309A3 WO 1992009309 A3 WO1992009309 A3 WO 1992009309A3 US 9108900 W US9108900 W US 9108900W WO 9209309 A3 WO9209309 A3 WO 9209309A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
medical devices
sterilizing
polyepoxy compounds
liquid sterilization
Prior art date
Application number
PCT/US1991/008900
Other languages
French (fr)
Other versions
WO1992009309A2 (en
Inventor
Roger Tu
Kalathi Thyagarajan
Harriet Chan Myers
Original Assignee
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int filed Critical Baxter Int
Priority to JP4502817A priority Critical patent/JPH06503018A/en
Publication of WO1992009309A2 publication Critical patent/WO1992009309A2/en
Publication of WO1992009309A3 publication Critical patent/WO1992009309A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/20—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom three- or four-membered rings

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicinal Preparation (AREA)

Abstract

A method is provided for sterilizing medical devices using a solution of polyepoxy compounds, particularly glycidyl ethers such as those registered under the trademark name Denacol R. These polyepoxy compounds are especially effective at concentrations as low as 2 to 4 volume percent in aqueous solution for sterilizing biologic medical devices, such as tissue heart valves or vascular grafts, without causing damage to the tissue of the implant and without leaving a residue on the device that is toxic to the tissue of the patient.
PCT/US1991/008900 1990-11-28 1991-11-25 Method of liquid sterilization WO1992009309A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4502817A JPH06503018A (en) 1990-11-28 1991-11-25 Liquid sterilization method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62022290A 1990-11-28 1990-11-28
US620,222 1990-11-28

Publications (2)

Publication Number Publication Date
WO1992009309A2 WO1992009309A2 (en) 1992-06-11
WO1992009309A3 true WO1992009309A3 (en) 1992-07-09

Family

ID=24485072

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1991/008900 WO1992009309A2 (en) 1990-11-28 1991-11-25 Method of liquid sterilization

Country Status (4)

Country Link
EP (1) EP0559819A1 (en)
JP (1) JPH06503018A (en)
CA (1) CA2095253A1 (en)
WO (1) WO1992009309A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4225795C2 (en) * 1992-07-31 1994-09-01 Schuelke & Mayr Gmbh Disinfectant based on carboxylic acid
DE4317083A1 (en) * 1993-02-11 1994-08-18 Menno Chemie Vertrieb Gmbh Parasiticidal disinfectant
US5679122A (en) * 1993-08-14 1997-10-21 Minnesota Mining & Manufacturing Company Filter for the filtration of a fluid flow
US5674298A (en) * 1994-10-21 1997-10-07 The Board Of Regents Of The University Of Michigan Calcification-resistant bioprosthetic tissue and methods of making same
US6379615B1 (en) 2000-02-24 2002-04-30 St. Jude Medical, Inc. Methods of sterilizing articles
DE10060660A1 (en) 2000-12-06 2002-06-20 Frey Rainer Preservation of biological prostheses comprises treating the prosthesis with a solution containing a mixture of epoxy compounds of different lengths and then with a solution containing an antithrombotic agent
US6468660B2 (en) 2000-12-29 2002-10-22 St. Jude Medical, Inc. Biocompatible adhesives
DE10317932A1 (en) * 2003-04-17 2004-11-18 Schülke & Mayr GmbH Chemothermal disinfection process
DE10317931A1 (en) * 2003-04-17 2004-11-11 Schülke & Mayr GmbH Chemothermal disinfection process
CN110475600B (en) 2017-04-11 2021-10-22 康明斯过滤Ip公司 Plate Filter Elements

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394370A (en) * 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
WO1984001894A1 (en) * 1982-11-12 1984-05-24 American Hospital Supply Corp Chemical sterilization of implantable biological tissue
EP0306256A2 (en) * 1987-08-31 1989-03-08 Koken Co. Ltd. Bioprosthetic valve

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394370A (en) * 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
WO1984001894A1 (en) * 1982-11-12 1984-05-24 American Hospital Supply Corp Chemical sterilization of implantable biological tissue
EP0306256A2 (en) * 1987-08-31 1989-03-08 Koken Co. Ltd. Bioprosthetic valve

Also Published As

Publication number Publication date
WO1992009309A2 (en) 1992-06-11
JPH06503018A (en) 1994-04-07
CA2095253A1 (en) 1992-05-29
EP0559819A1 (en) 1993-09-15

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