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WO1992014847A3 - Detection of high risk and low risk human papillomavirus by enzymatic amplification of dna - Google Patents

Detection of high risk and low risk human papillomavirus by enzymatic amplification of dna Download PDF

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Publication number
WO1992014847A3
WO1992014847A3 PCT/NL1992/000031 NL9200031W WO9214847A3 WO 1992014847 A3 WO1992014847 A3 WO 1992014847A3 NL 9200031 W NL9200031 W NL 9200031W WO 9214847 A3 WO9214847 A3 WO 9214847A3
Authority
WO
WIPO (PCT)
Prior art keywords
dna
human papillomavirus
high risk
risk
detection
Prior art date
Application number
PCT/NL1992/000031
Other languages
French (fr)
Other versions
WO1992014847A2 (en
Inventor
Israel Nur
Thierry Paper
Max Herzberg
Original Assignee
Orgenics International Holding
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orgenics International Holding filed Critical Orgenics International Holding
Publication of WO1992014847A2 publication Critical patent/WO1992014847A2/en
Publication of WO1992014847A3 publication Critical patent/WO1992014847A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A method for the identification of high risk and low risk human papillomavirus (HPV) types in a sample including the steps of hybridizing the sample with a consensus primer pair for amplifying DNA sequences of high risk and low risk HPV types, amplifying by an enzymatic reaction the DNA sequences which hybridize to the consensus primer pair and detecting amplified DNA sequences. A method for increasing efficiency and sensitivity of enzymatic DNA amplification by using primers having a sulfonated polycytidylic acid tail attached to them.
PCT/NL1992/000031 1991-02-13 1992-02-12 Detection of high risk and low risk human papillomavirus by enzymatic amplification of dna WO1992014847A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL97226A IL97226A0 (en) 1991-02-13 1991-02-13 Detection of high and low risk human papillomavirus by enzymatic amplification of dna
IL97226 1991-02-13

Publications (2)

Publication Number Publication Date
WO1992014847A2 WO1992014847A2 (en) 1992-09-03
WO1992014847A3 true WO1992014847A3 (en) 1993-01-21

Family

ID=11062099

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL1992/000031 WO1992014847A2 (en) 1991-02-13 1992-02-12 Detection of high risk and low risk human papillomavirus by enzymatic amplification of dna

Country Status (2)

Country Link
IL (1) IL97226A0 (en)
WO (1) WO1992014847A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07508891A (en) * 1993-05-06 1995-10-05 デイド、インターナショナル、インコーポレイテッド Human papillary species virus detection assay
SE9402518D0 (en) * 1994-07-18 1994-07-18 Pharmacia Biotech Ab Processing system
CA2237891C (en) 1995-11-15 2013-07-30 Gen-Probe Incorporated Nucleic acid probes complementary to human papillomavirus nucleic acid and related methods and kits

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006634A1 (en) * 1987-02-26 1988-09-07 The University Of Sydney A method of detection of carcinogenic human papillomavirus
WO1990001065A1 (en) * 1988-07-26 1990-02-08 Genelabs Incorporated Rna and dna amplification techniques
WO1990002821A1 (en) * 1988-09-09 1990-03-22 Cetus Corporation Detection of human papillomavirus by the polymerase chain reaction
EP0402132B1 (en) * 1989-06-08 1994-12-21 Takara Shuzo Co. Ltd. Method for the detection of human papilloma-virus

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006634A1 (en) * 1987-02-26 1988-09-07 The University Of Sydney A method of detection of carcinogenic human papillomavirus
WO1990001065A1 (en) * 1988-07-26 1990-02-08 Genelabs Incorporated Rna and dna amplification techniques
WO1990002821A1 (en) * 1988-09-09 1990-03-22 Cetus Corporation Detection of human papillomavirus by the polymerase chain reaction
EP0402132B1 (en) * 1989-06-08 1994-12-21 Takara Shuzo Co. Ltd. Method for the detection of human papilloma-virus

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Ann. Biol. Clin., vol. 47, 1989, Paris, FR; I. Nur et al.: "Chemiprobe TM, a nonradioactive system for labeling nucleic acid - Principles and applications", pages 91,92, see the whole article *
Gene, vol. 103, 1991, Elsevier Science Publ. B.V., Amsterdam, NL; T. Paper et al.: "Use of sulfonated primers to detect and type papillomavirus in cell cultures and cervical biopsies", pages 155-161, see the whole article *
Gene, vol. 108, 1991, Elsevier Science Publ. B.V., Amsterdam, NL; Yuka Uchimura et al.: "Nonradioactive labeling with chemically modified cytosine tails by the polymerase chain reaction", pages 103-108, see the whole article *
Journal of Medical Virology, vol. 27, February 1989, Alan R. Liss, Inc. P.B. Dallas et al.: "Polymerase chain reaction for fast, nonradioactive detection of high- and low-risk Papillomavirus Types in routine cervical specimens and in biopsies" pages 105-111, see abstract *
Journal of Medical Virology, vol. 27, no. 4, April 1989, Alan R. Liss, Inc., W. Melchers et al.: "Increased detection rate of human Papillomavirus in cervical scrapes by the polymerase chain reaction as compared to modified FISH and southern-blot analysis", pages 329-335, see page 330 *
Nucleic Acids Research, Symposium Series, no. 20, 1988, IRL Press Ltd, Oxford (GB), Akio Yamane et al.: "Rapid detection of specific gene sequences", pages 91,92 *

Also Published As

Publication number Publication date
WO1992014847A2 (en) 1992-09-03
IL97226A0 (en) 1992-05-25

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