WO1993018395A1 - Appareil permettant de determiner les proprietes physiques et/ou chimiques d'un echantillon et plus particulierement un echantillon de sang - Google Patents
Appareil permettant de determiner les proprietes physiques et/ou chimiques d'un echantillon et plus particulierement un echantillon de sang Download PDFInfo
- Publication number
- WO1993018395A1 WO1993018395A1 PCT/GB1993/000475 GB9300475W WO9318395A1 WO 1993018395 A1 WO1993018395 A1 WO 1993018395A1 GB 9300475 W GB9300475 W GB 9300475W WO 9318395 A1 WO9318395 A1 WO 9318395A1
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- WIPO (PCT)
- Prior art keywords
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- Prior art date
Links
- 210000004369 blood Anatomy 0.000 title claims abstract description 41
- 239000008280 blood Substances 0.000 title claims abstract description 41
- 239000000126 substance Substances 0.000 title claims abstract description 25
- 238000000034 method Methods 0.000 claims abstract description 57
- 238000005259 measurement Methods 0.000 claims abstract description 43
- 108010049003 Fibrinogen Proteins 0.000 claims abstract description 29
- 102000008946 Fibrinogen Human genes 0.000 claims abstract description 29
- 229940012952 fibrinogen Drugs 0.000 claims abstract description 29
- 210000003743 erythrocyte Anatomy 0.000 claims abstract description 13
- 238000004062 sedimentation Methods 0.000 claims abstract description 12
- 239000000523 sample Substances 0.000 claims description 100
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- 239000013078 crystal Substances 0.000 claims description 12
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- 229910000859 α-Fe Inorganic materials 0.000 description 2
- 239000002028 Biomass Substances 0.000 description 1
- 229910001369 Brass Inorganic materials 0.000 description 1
- 206010011409 Cross infection Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 102000018697 Membrane Proteins Human genes 0.000 description 1
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- 238000012937 correction Methods 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 230000009699 differential effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 239000008151 electrolyte solution Substances 0.000 description 1
- 229940021013 electrolyte solution Drugs 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000002489 hematologic effect Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 239000006249 magnetic particle Substances 0.000 description 1
- 238000007620 mathematical function Methods 0.000 description 1
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- 239000002245 particle Substances 0.000 description 1
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- 230000002441 reversible effect Effects 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/05—Investigating sedimentation of particle suspensions in blood
Definitions
- any of the measuring cells methods, and apparatus referred to herein as belonging to this invention may be operated in a differential mode , i:e using two identical sets of said cells , devices or apparatus with the sample being placed in /measured by one member of said set and a dummy sample, containing for example air, water or electroloyte etc; being placed in /measured by second member of said set.
- a differential mode i:e using two identical sets of said cells , devices or apparatus with the sample being placed in /measured by one member of said set and a dummy sample, containing for example air, water or electroloyte etc; being placed in /measured by second member of said set.
- FIG 9 the block diagram of the aspect of the invention concerned with fibrinogen or protein assessment when a numeric entry parameter (e:g haemoglobin ) is available or known.
- a numeric entry parameter e:g haemoglobin
- Haemoglobin content of blood is known or available from another source such as Coulter or similar cell counter or biochemical optical haemoglobinometer, and is used as the said external entry parameter then the invention configured according to this aspect can be used to provide a simpler and more accurate assessment of fibrinogen level.
- the main component parts of the system 78-81 operate in exactly the same accord as their equivalent parts indicated in figure 2.
- the digital voltmeter 84 is used with a differential input and temperature is compensated for using potentiometer 82.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
L'invention concerne un appareil et un procédé permettant de mettre en corrélation certaines propriétés physiques et chimiques d'un échantillon de sang ou de toute autre substance par la mesure à distance multi-fréquence simultanée du diélectrique, ou lorsqu'une fréquence donnée est appliquée et comparée à un paramètre extérieur proportionnel à l'ampleur d'un paramètre diélectrique sélectionné à une ou plusieurs autres fréquences. L'appareil est utilisé plus particulièrement pour l'évaluation précise instantannée de l'état de sédimentation prévisible de globules rouges ou d'autres paramètres se rapportant aux fibrinogènes ou aux érythrocytes.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93905532A EP0630471A1 (fr) | 1992-03-10 | 1993-03-08 | Appareil permettant de determiner les proprietes physiques et/ou chimiques d'un echantillon et plus particulierement un echantillon de sang |
| AU36429/93A AU677001B2 (en) | 1992-03-10 | 1993-03-08 | Apparatus for determining the physical and/or chemical properties of a sample, particularly of blood |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9205175A GB2260407B (en) | 1991-10-10 | 1992-03-10 | Method and devices for A.C measurement on all electromagnetically permeable matter, preferably liquid blood |
| GB9205175.4 | 1992-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO1993018395A1 true WO1993018395A1 (fr) | 1993-09-16 |
Family
ID=10711820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/GB1993/000475 WO1993018395A1 (fr) | 1992-03-10 | 1993-03-08 | Appareil permettant de determiner les proprietes physiques et/ou chimiques d'un echantillon et plus particulierement un echantillon de sang |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0630471A1 (fr) |
| AU (1) | AU677001B2 (fr) |
| WO (1) | WO1993018395A1 (fr) |
Cited By (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995014224A1 (fr) * | 1993-11-15 | 1995-05-26 | Swelab Instrument Ab | Appareil pour determiner la vitesse de sedimentation des eryhtrocytes |
| US5583432A (en) * | 1994-04-11 | 1996-12-10 | Sci-Nostics Limited | Electrical method and apparatus for non-contact determination of physical and/or chemical properties of a sample, particularly of blood |
| WO1998046985A1 (fr) * | 1997-04-16 | 1998-10-22 | Kaiku Limited | Evaluation de la composition des liquides |
| GB2336685A (en) * | 1998-04-21 | 1999-10-27 | Christopher Barnes | Capacitance measuring system |
| WO2000052453A3 (fr) * | 1999-02-28 | 2001-04-19 | Steag Micro Tech Gmbh | Procede permettant de determiner les proprietes d'un agent |
| WO2002073179A1 (fr) * | 2001-03-13 | 2002-09-19 | Hall Effect Technologies Ltd. | Appareil et procede pour l'analyse de liquides |
| EP1299029B1 (fr) * | 2001-03-06 | 2006-11-22 | Solianis Holding AG | Dispositif destines a determiner la concentration de glucose dans un liquide corporel |
| US7184810B2 (en) | 2002-09-04 | 2007-02-27 | Solianis Holding Ag | Method and a device for measuring glucose |
| KR20070034169A (ko) * | 2005-09-23 | 2007-03-28 | 삼성전자주식회사 | 테라헤르츠파를 이용한 혈중 성분 농도 측정 장치 및 방법 |
| GB2435097A (en) * | 2005-09-30 | 2007-08-15 | Christopher Barnes | Assessing erythrocyte membranes using electromagnetic and ultrasound energy. |
| US7315767B2 (en) | 2001-03-06 | 2008-01-01 | Solianis Holding Ag | Impedance spectroscopy based systems and methods |
| US7534208B2 (en) | 2002-09-24 | 2009-05-19 | Max Link | Device for the measurement of glucose concentrations |
| RU2393476C2 (ru) * | 2008-08-26 | 2010-06-27 | Государственное образовательное учреждение высшего профессионального образования Иркутский государственный университет | Устройство для диагностики функционального состояния крови человека |
| WO2011144511A1 (fr) | 2010-05-11 | 2011-11-24 | Fresenius Medical Care Deutschland Gmbh | Procédé et dispositif pour déterminer des fractions cellulaires et/ou extracellulaires, en particulier macromoléculaires, de liquides, de préférence de liquides organiques d'êtres vivants |
| US8197406B2 (en) | 2003-12-02 | 2012-06-12 | Biovotion Ag | Device and method for measuring a property of living tissue |
| US8200307B2 (en) | 2004-06-07 | 2012-06-12 | Biovotion Ag | Method and device for determining a parameter of living tissue |
| WO2014113333A1 (fr) * | 2013-01-15 | 2014-07-24 | The Regents Of The University Of California | Dispositif portatif d'imagerie par spectroscopie optique diffuse à large bande pour caractérisation non invasive d'un tissu |
| US9179856B2 (en) | 2009-04-17 | 2015-11-10 | Biovotion Ag | Sensing device for body tissue properties |
| US9568449B2 (en) | 2012-01-06 | 2017-02-14 | Bend Research, Inc. | Dielectric spectroscopy methods and apparatus |
| US9713447B2 (en) | 2005-11-10 | 2017-07-25 | Biovotion Ag | Device for determining the glucose level in body tissue |
| GB2547271A (en) * | 2016-02-11 | 2017-08-16 | Barnes Christopher | A contact free blood assessment device and method |
| EP2375244B1 (fr) * | 2009-01-08 | 2019-10-30 | Sony Corporation | Analyseur du système de coagulation sanguine, de même que procédé et programme d'analyse de système de coagulation sanguine |
| US11879860B2 (en) | 2019-06-11 | 2024-01-23 | Fresenius Medical Care Holdings, Inc. | Systems and methods for measuring electrical characteristic of medical fluids |
| US12059519B2 (en) | 2021-01-11 | 2024-08-13 | Fresenius Medical Care Holdings, Inc. | Systems and methods for measuring electrical characteristic of medical fluids |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2400669B (en) * | 2003-04-17 | 2005-12-14 | * Barnes Christopher | A method and device to obtain haematological parameters and indicators by means of harnessing the dynamics of erythrocyte and other aggregation |
| GB2414558B (en) * | 2003-10-10 | 2006-04-19 | Christopher Barnes | Apparatus and method for tracking changes in composition or concentration of a fluid or one or more component parts thereof |
Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB595720A (en) * | 1944-11-06 | 1947-12-15 | Ace Electronics Ltd | Electrical apparatus for measuring the proportions of mixtures and solutions |
| GB1018188A (en) * | 1962-11-01 | 1966-01-26 | Kaiser Nils | Method for testing the chemical and/or physical condition of media |
| GB1084860A (en) * | 1965-08-24 | 1967-09-27 | Kaiser Nils | Improvements in or relating to devices for investigating the chemical and/or physical nature of substance |
| US3483860A (en) * | 1964-11-02 | 1969-12-16 | Norman Stanley Namerow | Method for monitoring intrasomatic circulatory functions and organ movement |
| FR2201762A5 (fr) * | 1972-09-29 | 1974-04-26 | Inst Nat Sante Rech Med | |
| FR2378282A1 (fr) * | 1977-01-22 | 1978-08-18 | Labora Mannheim Gmbh | Dispositif pour determiner la vitesse de sedimentation du sang |
| US4135131A (en) * | 1977-10-14 | 1979-01-16 | The United States Of America As Represented By The Secretary Of The Army | Microwave time delay spectroscopic methods and apparatus for remote interrogation of biological targets |
| US4257001A (en) * | 1979-04-13 | 1981-03-17 | John G. Abramo | Resonant circuit sensor of multiple properties of objects |
| GB2130728A (en) * | 1982-09-23 | 1984-06-06 | De Beers Ind Diamond | Measuring settling rates |
| EP0157496A2 (fr) * | 1984-03-28 | 1985-10-09 | Northern Telecom Limited | Procédé pour mesurer la quantité de particules à forte permittivité dans un matériau porteur |
| DE3637549A1 (de) * | 1986-11-04 | 1988-05-11 | Hans Dr Med Rosenberger | Messgeraet zur pruefung der dielektrischen eigenschaften biologischer gewebe |
| DE3722213A1 (de) * | 1987-07-04 | 1989-01-12 | Klaus Weber | Messverfahren zur bestimmung der konzentration eines mediums |
| WO1991009295A1 (fr) * | 1989-12-13 | 1991-06-27 | Tesi Ab | Procede et dispositif de determination du taux de sedimentation du sang |
| GB2248301A (en) * | 1990-09-12 | 1992-04-01 | Ici Plc | Apparatus and method for the detection of changes in the composition of a material |
-
1993
- 1993-03-08 EP EP93905532A patent/EP0630471A1/fr not_active Withdrawn
- 1993-03-08 AU AU36429/93A patent/AU677001B2/en not_active Ceased
- 1993-03-08 WO PCT/GB1993/000475 patent/WO1993018395A1/fr not_active Application Discontinuation
Patent Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB595720A (en) * | 1944-11-06 | 1947-12-15 | Ace Electronics Ltd | Electrical apparatus for measuring the proportions of mixtures and solutions |
| GB1018188A (en) * | 1962-11-01 | 1966-01-26 | Kaiser Nils | Method for testing the chemical and/or physical condition of media |
| US3483860A (en) * | 1964-11-02 | 1969-12-16 | Norman Stanley Namerow | Method for monitoring intrasomatic circulatory functions and organ movement |
| GB1084860A (en) * | 1965-08-24 | 1967-09-27 | Kaiser Nils | Improvements in or relating to devices for investigating the chemical and/or physical nature of substance |
| FR2201762A5 (fr) * | 1972-09-29 | 1974-04-26 | Inst Nat Sante Rech Med | |
| FR2378282A1 (fr) * | 1977-01-22 | 1978-08-18 | Labora Mannheim Gmbh | Dispositif pour determiner la vitesse de sedimentation du sang |
| US4135131A (en) * | 1977-10-14 | 1979-01-16 | The United States Of America As Represented By The Secretary Of The Army | Microwave time delay spectroscopic methods and apparatus for remote interrogation of biological targets |
| US4257001A (en) * | 1979-04-13 | 1981-03-17 | John G. Abramo | Resonant circuit sensor of multiple properties of objects |
| GB2130728A (en) * | 1982-09-23 | 1984-06-06 | De Beers Ind Diamond | Measuring settling rates |
| EP0157496A2 (fr) * | 1984-03-28 | 1985-10-09 | Northern Telecom Limited | Procédé pour mesurer la quantité de particules à forte permittivité dans un matériau porteur |
| DE3637549A1 (de) * | 1986-11-04 | 1988-05-11 | Hans Dr Med Rosenberger | Messgeraet zur pruefung der dielektrischen eigenschaften biologischer gewebe |
| DE3722213A1 (de) * | 1987-07-04 | 1989-01-12 | Klaus Weber | Messverfahren zur bestimmung der konzentration eines mediums |
| WO1991009295A1 (fr) * | 1989-12-13 | 1991-06-27 | Tesi Ab | Procede et dispositif de determination du taux de sedimentation du sang |
| GB2248301A (en) * | 1990-09-12 | 1992-04-01 | Ici Plc | Apparatus and method for the detection of changes in the composition of a material |
Non-Patent Citations (1)
| Title |
|---|
| PROCEEDINGS OF THE ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY vol. 10, November 1988, NEW ORLEANS pages 761 - 762 J.M. MCKEE ET AL. 'RADIOFREQUENCY FINGER IMPEDANCE MEASUREMENTS' * |
Cited By (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995014224A1 (fr) * | 1993-11-15 | 1995-05-26 | Swelab Instrument Ab | Appareil pour determiner la vitesse de sedimentation des eryhtrocytes |
| US5583432A (en) * | 1994-04-11 | 1996-12-10 | Sci-Nostics Limited | Electrical method and apparatus for non-contact determination of physical and/or chemical properties of a sample, particularly of blood |
| US6511851B1 (en) | 1997-04-16 | 2003-01-28 | Kaiku Limited | Identifying changes in composition of liquids |
| WO1998046985A1 (fr) * | 1997-04-16 | 1998-10-22 | Kaiku Limited | Evaluation de la composition des liquides |
| GB2336685A (en) * | 1998-04-21 | 1999-10-27 | Christopher Barnes | Capacitance measuring system |
| GB2336685B (en) * | 1998-04-21 | 2002-05-15 | Christopher Barnes | A method and device for the measurement of fixed or time varying capacitance |
| WO2000052453A3 (fr) * | 1999-02-28 | 2001-04-19 | Steag Micro Tech Gmbh | Procede permettant de determiner les proprietes d'un agent |
| EP1299029B1 (fr) * | 2001-03-06 | 2006-11-22 | Solianis Holding AG | Dispositif destines a determiner la concentration de glucose dans un liquide corporel |
| US7315767B2 (en) | 2001-03-06 | 2008-01-01 | Solianis Holding Ag | Impedance spectroscopy based systems and methods |
| US7693561B2 (en) | 2001-03-06 | 2010-04-06 | Solianis Holding Ag | Method and device for determining the concentration of a substance in body liquid |
| WO2002073179A1 (fr) * | 2001-03-13 | 2002-09-19 | Hall Effect Technologies Ltd. | Appareil et procede pour l'analyse de liquides |
| US7184810B2 (en) | 2002-09-04 | 2007-02-27 | Solianis Holding Ag | Method and a device for measuring glucose |
| US7534208B2 (en) | 2002-09-24 | 2009-05-19 | Max Link | Device for the measurement of glucose concentrations |
| US8197406B2 (en) | 2003-12-02 | 2012-06-12 | Biovotion Ag | Device and method for measuring a property of living tissue |
| US8200307B2 (en) | 2004-06-07 | 2012-06-12 | Biovotion Ag | Method and device for determining a parameter of living tissue |
| KR20070034169A (ko) * | 2005-09-23 | 2007-03-28 | 삼성전자주식회사 | 테라헤르츠파를 이용한 혈중 성분 농도 측정 장치 및 방법 |
| GB2435097A (en) * | 2005-09-30 | 2007-08-15 | Christopher Barnes | Assessing erythrocyte membranes using electromagnetic and ultrasound energy. |
| GB2435097B (en) * | 2005-09-30 | 2009-08-05 | Christopher Barnes | Method and apparatus for assessment of the state of a collection of erythrocytemembranes |
| US9713447B2 (en) | 2005-11-10 | 2017-07-25 | Biovotion Ag | Device for determining the glucose level in body tissue |
| RU2393476C2 (ru) * | 2008-08-26 | 2010-06-27 | Государственное образовательное учреждение высшего профессионального образования Иркутский государственный университет | Устройство для диагностики функционального состояния крови человека |
| US11067523B2 (en) | 2009-01-08 | 2021-07-20 | Sony Corporation | Blood coagulation system analysis device, and method and program for analysis of blood coagulation system |
| EP2375244B1 (fr) * | 2009-01-08 | 2019-10-30 | Sony Corporation | Analyseur du système de coagulation sanguine, de même que procédé et programme d'analyse de système de coagulation sanguine |
| EP3620780A1 (fr) * | 2009-01-08 | 2020-03-11 | SONY Corporation | Dispositif d'analyse de système de coagulation sanguine et procédé et programme d'analyse de système de coagulation sanguine |
| US9179856B2 (en) | 2009-04-17 | 2015-11-10 | Biovotion Ag | Sensing device for body tissue properties |
| WO2011144511A1 (fr) | 2010-05-11 | 2011-11-24 | Fresenius Medical Care Deutschland Gmbh | Procédé et dispositif pour déterminer des fractions cellulaires et/ou extracellulaires, en particulier macromoléculaires, de liquides, de préférence de liquides organiques d'êtres vivants |
| US9823207B2 (en) | 2010-05-11 | 2017-11-21 | Fresenius Medical Care Deutschland Gmbh | Method and device for determining intracellular and/or extracellular, in particular macromolecular fractions of fluids, preferably of body fluids of living organisms |
| US9568449B2 (en) | 2012-01-06 | 2017-02-14 | Bend Research, Inc. | Dielectric spectroscopy methods and apparatus |
| WO2014113333A1 (fr) * | 2013-01-15 | 2014-07-24 | The Regents Of The University Of California | Dispositif portatif d'imagerie par spectroscopie optique diffuse à large bande pour caractérisation non invasive d'un tissu |
| GB2547271A (en) * | 2016-02-11 | 2017-08-16 | Barnes Christopher | A contact free blood assessment device and method |
| GB2547271B (en) * | 2016-02-11 | 2020-07-22 | Barnes Christopher | A Contact Free Blood Assessment Device and Method |
| US11879860B2 (en) | 2019-06-11 | 2024-01-23 | Fresenius Medical Care Holdings, Inc. | Systems and methods for measuring electrical characteristic of medical fluids |
| US12276628B2 (en) | 2019-06-11 | 2025-04-15 | Fresenius Medical Care Holdings, Inc. | Systems and methods for measuring electrical characteristic of medical fluids |
| US12059519B2 (en) | 2021-01-11 | 2024-08-13 | Fresenius Medical Care Holdings, Inc. | Systems and methods for measuring electrical characteristic of medical fluids |
Also Published As
| Publication number | Publication date |
|---|---|
| AU3642993A (en) | 1993-10-05 |
| EP0630471A1 (fr) | 1994-12-28 |
| AU677001B2 (en) | 1997-04-10 |
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