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WO1993018802A1 - Systeme de regulation de debit et de pression de liquide - Google Patents

Systeme de regulation de debit et de pression de liquide Download PDF

Info

Publication number
WO1993018802A1
WO1993018802A1 PCT/US1993/001261 US9301261W WO9318802A1 WO 1993018802 A1 WO1993018802 A1 WO 1993018802A1 US 9301261 W US9301261 W US 9301261W WO 9318802 A1 WO9318802 A1 WO 9318802A1
Authority
WO
WIPO (PCT)
Prior art keywords
chamber
fluid flow
fluid
accumulator
pressure
Prior art date
Application number
PCT/US1993/001261
Other languages
English (en)
Inventor
Erik W. Peterson
Original Assignee
Alcon Surgical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Surgical, Inc. filed Critical Alcon Surgical, Inc.
Publication of WO1993018802A1 publication Critical patent/WO1993018802A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71Suction drainage systems
    • A61M1/77Suction-irrigation systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71Suction drainage systems
    • A61M1/72Cassettes forming partially or totally the fluid circuit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/02Enemata; Irrigators
    • A61M3/0201Cassettes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/00736Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/12General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3379Masses, volumes, levels of fluids in reservoirs, flow rates
    • A61M2205/3382Upper level detectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0612Eyes

Definitions

  • the present invention relates to microsurgical equipment and, in particular, to ultrasonic microsurgical handpieces, irrigation/aspiration handpieces and control systems.
  • a typical (anterior chamber) ultrasonic surgical device consists of an ultrasonically driven handpiece with attached cutting tip and irrigating sleeve and an electronic control console.
  • the handpiece assembly or probe is attached to the control console by an electric cable and flexible tubings. Through the electric cable, the console varies the power level transmitted by the handpiece to the attached cutting tip and the flexible tubings supply irrigation fluid to and draw aspiration fluid from the eye through the handpiece assembly.
  • a typical posterior segment surgical tool consists of a handpiece having a long, hollow outer needle or probe with a cutting port and a reciprocating or rotating hollow inner cutting needle. As the inner cutting needle cuts tissue through the cutting port, the severed tissue is aspirated into the inner needle through the cutting port and out of the handpiece by a flexible tube connected to a source of reduced pressure at the surgical tool control console. Material aspirated from the surgical site is replaced by an infusion fluid, such as saline solution, generally dispensed within the surgical site by a second, hollow infusion needle or probe.
  • Posterior segment surgical tools are more fully described in U.S. Patents Nos. 3,996,935, 4,200,106, 4,696,298, 4,850,354 and 4,867,155, the entire contents of which are incorporated herein by reference.
  • the fluid handling connections have come to be centralized in a "cassette" which contains in one unit connections for the aspiration and irrigation lines, internal conduits for directing the flow of fluids and a collection container for aspirated fluid and tissue.
  • the cassette typically is supplied in a sterile package with the connecting tubing already attached.
  • the receptacle contains a device or devices to exercise control over the flow of fluids through the fluid conduits within the cassette.
  • the cassette usually is discarded after a single use but also may be reusable if made from autoclavable materials.
  • Ophthalmic surgeons generally prefer to use the type of vacuum pump on which they were trained. Many cataract surgeons are trained on peristaltic pumps and, accordingly, they tend to prefer these pumps. On the other hand, a significant number of posterior segment surgeons are trained on venturi or diaphragm pumps and, of course, such systems tend to be preferred. However, pump preferences are based not only on these training factors, but equally significantly to pump selection are the different performance characteristics for each type of pump. For example, when performing anterior segment surgery (e.g. cataract surgery), most surgeons prefer the constant flow characteristics of a peristaltic pump that help to prevent chamber collapse upon the break-up of any occluding tissue. On the other hand, during posterior segment surgery (e.g. vitrectomy surgery), surgeons prefer the constant pressure of a diaphragm or venturi pumping system.
  • U.S. Patent No. 3,496,878 to Hargest, et al includes a peristaltic pump and a sensor that monitors the flow of fluid into a chamber to trigger operation of the pump.
  • this system does not contain a fluid flow controller and does not have the capability of alternatively providing constant flow or constant pressure.
  • U.S. Patent No. 4,385,630 to Gilcher, et al. discloses a blood donation unit that includes a peristaltic pump and a pressure bag that monitors blood flow and actuates the pump. This system likewise does not have the capability of alternatively providing constant flow or constant pressure.
  • the system disclosed in U.S. Patent No. 4,604,089 to Santangelo, et al. includes a pressure accumulator that allows the surgeon to vary the pressure level within the irrigation system between one of two preselected pressures by opening and closing two push button valves.
  • This system does not contain any means for alternately providing constant fluid flow or constant fluid pressure.
  • the present invention improves upon prior art fluid flow control systems by providing a system having an accumulator in fluid communication with a surgical handpiece and a volume sensor responsive to changes in fluid volume within the accumulator. Sensed volume changes are transmitted to a pressure controller and a flow controller through a microcomputer that adjusts the controllers to provide either a desired flow rate or a desired pressure level at the surgical handpiece.
  • one objective of the system of the present invention is to provide an improved fluid flow control system for use in surgical procedures requiring irrigation or aspiration.
  • FIG. 1 is a schematic illustration of a first embodiment of the fluid flow and pressure control system of the present invention for use in surgical procedures requiring aspiration.
  • FIG. 2 is a schematic illustration of a second embodiment of the fluid flow and pressure control system of the present invention for use in surgical procedures requiring irrigation.
  • FIG. 3 is a plan view of the fluid accumulator used in the system of the present invention.
  • FIG. 4 is a cross-sectional view of the fluid accumulator used in the system of the present invention taken at line 4-4 in FIG. 3.
  • FIG. 5 is a schematic illustration of a third embodiment of the fluid flow and pressure control system of the present invention.
  • FIG. 6 is an enlarged, fragmentary, cross-sectional view of the accumulator/sensor of the present invention taken at circle 6 in FIG. 5.
  • fluid flow and pressure control system 10 of the present invention generally contains fluid accumulator 3, pressure controller 29, fluid flow controller 21, volume sensor 13 and computer 17.
  • Pressure controller 29 may be any suitable vacuum-type pump such as a diaphragm or venturi pump.
  • Computer 17 preferable is an embedded controller such as the INTEL ® model 80196.
  • Accumulator 3 generally is located within cassette portion 45 of system 10 and contains first chamber or portion 7 and second chamber or portion 9. As can be seen in FIGS. 5 and 6, accumulator 3 may be placed near outside wall 47 of cassette portion 45 so as to be proximate sensor 13, which is contained within console portion 49 of system 10. First chamber 7 and second chamber 9 may be separated by fixed, resilient membrane 11.
  • accumulator 3 may be divided into first chamber 7 and second chamber 9 by filling accumulator 3 with two immiscible fluids, such as a liquid and a gas.
  • First chamber 7 communicates with pressure controller 29 through conduit 31 and second chamber 9 communicates with fluid flow controller 21 through conduit 23 and with tool or handpiece 5 through flexible conduit 1.
  • membrane 11 is preferably made from silicone rubber or other suitably compliant elastic material .
  • volume sensor 13 may consist of a pair of concentric electrode plates 37 and 39 either proximate to (FIG. 6) or contained within (FIG. 4) first chamber 7 of accumulator 3 and connected to an oscillator circuit (not shown) in the console through cable 15.
  • electrode plates 37 and 39 may be located directly on circuit board 69. Electrode plate 37 and the liquid in second chamber 9 opposite electrode plate 37 form two plates of a capacitor. Likewise, electrode plate 39 and the liquid in second chamber 9 opposite electrode plate 39 form two plates of a second capacitor.
  • volume sensor 13 can detect minute volume changes in the liquid in second chamber 9 and communicates this information to computer 17 through cable 19. While volume sensor 13 as described above is preferred, other volume sensors 13, such as electrode or probe systems, photoelectric-cell systems, floats systems or thermo-hydraulic systems may also be used. As can be seen in FIG.
  • system 10 when system 10 is used to control aspiration fluid flow and pressure, system 10 further includes aspiration fluid collection container 27 that communicates with fluid flow controller 21 through conduit 24.
  • Container 27 may be integrally formed in cassette chamber 45 of system 10 or may be a separate container.
  • Fluid flow controller 21 may be any suitable pump but a peristaltic pump is preferred.
  • system 10 when system 10 is used to control irrigation fluid flow and pressure, system 10 further includes an irrigation fluid source 25 that is connected to fluid flow controller 21a through conduit 55 and flow sensor 57.
  • Fluid flow controller 21a may be a peristaltic pump or, if fluid source 25 is pressurized, fluid flow controller 21a may be a variable orifice valve or a valve having a variable on/off cycle.
  • Flow sensor 57 through cable 59, provides computer 17 with the fluid flow data necessary to calculate the fluid flow rate through conduit 1 and permits computer 17 to calculate the pressure drop across conduit 1.
  • Flow sensor 57 can be any sensor suitable for measuring fluid flow in a closed conduit and can be contained within the console of system 10 or be part of fluid source 25 and conduit 55 (i.e.. a drop counter). If a peristaltic pump is used as fluid flow controller 21a in an irrigation fluid flow system, the flow rate through the system can be determined from the pump speed and flow sensor 57 may be omitted.
  • Second chamber 9 is filled with fluid and system 10 is zeroed. If the surgeon has selected a target fluid flow rate, computer 17 activates fluid flow controller 21 through cable 35 and fluid flow controller 21 begins to draw fluid from second chamber 9 through conduit 23 and discharges the fluid into container 27 through conduit 24. Computer 17 adjusts the speed of fluid flow controller 21 to achieve the approximate desired flow rate. However, if the flow of fluid from the surgical site through handpiece 5 and conduit 1 is too low, fluid flow controller 21 will begin to draw down the volume of fluid in second chamber 9. This volume change is detected by volume sensor 13 and is communicated to computer 17.
  • computer 17, through cable 33 directs pressure controller 29 to reduce the absolute pressure in first chamber 7.
  • This reduced pressure in first chamber 7 is communicated to second chamber 9, reducing the pressure in second chamber 9 and causing increased fluid flow at the operative site through handpiece 5 and conduit 1 and into second chamber 9.
  • computer 17 directs pressure controller 29 to increase the pressure in accumulator 3, thereby reducing the flow rate at the operative site through handpiece 5 and conduit 1 and into second chamber 9.
  • the flow rate through handpiece 5 and conduit 1 is controlled by pressure controller 29 varying the pressure within accumulator 3, and fluid flow controller 21 operates at essentially a constant speed.
  • second chamber 9 is filled with fluid and system 10 is zeroed.
  • Computer 17 activates pressure controller 29 to reduce the absolute pressure in first chamber 7 to approximately the target pressure and this reduced pressure level is communicated to second chamber 9, thereby causing fluid to flow into second chamber 9.
  • computer 17, through cable 35 activates fluid flow controller 21. If the amount of fluid drawn from second chamber 9 by fluid flow controller 21 is too great, the volume of fluid in second chamber 9 will decrease, and this volume decrease will be detected by sensor 13 and transmitted to computer 17.
  • Computer 17 will reduce the speed of fluid flow controller 21 so that the volume of fluid in second chamber 9 remains constant.
  • fluid flow controller 21a is a valve instead of a peristaltic pump
  • the liquid level in accumulator 3 is adjusted by opening and closing fluid flow controller 21a or variably throttling fluid flow controller 21a so as to maintain a constant volume of liquid in accumulator 3.
  • system 10 can be adapted to hybrid modes of operation combining aspects of both.
  • the surgeon might select, in addition to a target flow rate, a minimum absolute pressure level (maximum vacuum level).
  • System 10 will respond in a constant flow mode as long as the pressure level within the system did not reach the minimum level but respond in a constant pressure mode once the minimum pressure level was reached.
  • the surgeon can select a target pressure and a maximum flow rate level.
  • System 10 will respond in a constant pressure mode as long as the flow rate does not exceed the maximum level but respond in a constant flow rate mode once the maximum flow level is reached.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • External Artificial Organs (AREA)

Abstract

Système (10) de régulation du débit et de la pression d'un liquide doté d'un accumulateur (3) possédant une première chambre (7) et une seconde chambre (9) séparées par une membrane souple (11), un diaphragme ou une pompe venturi (29) en communication liquide avec la première chambre (7), une pompe ou soupape péristaltique (21) en communication liquide avec la seconde chambre (9), un détecteur de volume (13) communiquant avec l'accumulateur (3), destiné à détecter les modifications de volume dans la seconde chambre (9), un instrument chirurgical (5) en communication liquide avec la seconde chambre (9) et un ordinateur (17) destiné à commander le fonctionnement du diaphragme ou de la pompe venturi (29) et de la pompe péristaltique (21) en réponse à une signal produit par le détecteur de volume (13).
PCT/US1993/001261 1992-03-20 1993-02-12 Systeme de regulation de debit et de pression de liquide WO1993018802A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85600392A 1992-03-20 1992-03-20
US07/856,003 1992-03-20

Publications (1)

Publication Number Publication Date
WO1993018802A1 true WO1993018802A1 (fr) 1993-09-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/001261 WO1993018802A1 (fr) 1992-03-20 1993-02-12 Systeme de regulation de debit et de pression de liquide

Country Status (2)

Country Link
AU (1) AU3665193A (fr)
WO (1) WO1993018802A1 (fr)

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003047652A1 (fr) * 2001-11-30 2003-06-12 Bausch & Lomb Incorporated Reservoir de collecte s'utilisant avec un regulateur de debit
WO2003047653A1 (fr) * 2001-11-30 2003-06-12 Bausch & Lomb Incorporated Detecteur et regulateur de debit d'aspiration
US6986753B2 (en) * 1998-05-21 2006-01-17 Buivision Constant ocular pressure active infusion system
JP2008149148A (ja) * 2006-12-18 2008-07-03 Alcon Inc 吸引室内の流体流を制御するためのシステム及び方法
JP2008543487A (ja) * 2005-06-21 2008-12-04 アルコン,インコーポレイティド 流量監視による吸引制御
JP2009530048A (ja) * 2006-03-20 2009-08-27 アルコン,インコーポレイティド 多領域の流体室を有する手術カセット
WO2010059760A1 (fr) * 2008-11-21 2010-05-27 Bausch & Lomb Incorporated Appareil et procédé de commande d'une source de vide pour établissement d'un écoulement de fluide
US7775780B2 (en) 2006-01-24 2010-08-17 Alcon, Inc. Surgical cassette
US8006570B2 (en) 2006-03-29 2011-08-30 Alcon, Inc. Non-invasive flow measurement
DE102010010336A1 (de) * 2010-03-04 2011-09-08 Geuder Ag Steuer-/Versorgungseinheit zum Betreiben eines medizinischen Handgeräts
DE102010010335A1 (de) * 2010-03-04 2011-09-08 Geuder Ag Steuer-/Versorgungseinheit zum Betreiben eines medizinischen Handgeräts und dazu passende Kassette
US8079836B2 (en) 2006-03-01 2011-12-20 Novartis Ag Method of operating a peristaltic pump
US8251944B2 (en) 2006-03-29 2012-08-28 Novartis Ag Surgical system having a cassette with an acoustic coupling
US8343100B2 (en) 2006-03-29 2013-01-01 Novartis Ag Surgical system having a non-invasive flow sensor
US8465467B2 (en) 2006-09-14 2013-06-18 Novartis Ag Method of controlling an irrigation/aspiration system
US8545198B2 (en) 2005-11-17 2013-10-01 Novartis Ag Surgical cassette
CN104168933A (zh) * 2012-03-12 2014-11-26 弗雷泽纽斯医疗保健控股有限公司 用于从液体中排出气体的装置和方法
US20150164690A1 (en) * 2013-12-17 2015-06-18 Medical Instrument Development Laboratories, Inc. Diaphragm-position-controlled, multi-mode ocular fluid management system and method
DE102016201297B3 (de) 2016-01-28 2017-03-30 Carl Zeiss Meditec Ag Ophthalmochirugisches System
CN109922764A (zh) * 2016-11-03 2019-06-21 This股份公司 无菌的文丘里吸出
US10722619B2 (en) 2016-01-28 2020-07-28 Carl Zeiss Meditec Ag Method for operating an ophthalmosurgical system
US11110218B2 (en) 2012-09-06 2021-09-07 D.O.R.C. Dutch Ophthalmic Research Center (International) B.V. Surgical cartridge, pump and surgical operating machine
US11116878B2 (en) 2017-11-16 2021-09-14 Alcon Inc. Fluidics aspiration system
US20230256165A1 (en) * 2022-02-16 2023-08-17 Medtronic, Inc. Optionally pulsatile flow generating implantable pump

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3812855A (en) * 1971-12-15 1974-05-28 Surgical Design Corp System for controlling fluid and suction pressure
EP0037992A1 (fr) * 1980-04-14 1981-10-21 Thomas Jefferson University Liquide cérébrospinal, méthode de fabrication d'un tel liquide et appareil destiné à sa mise en oeuvre
EP0154681A1 (fr) * 1983-12-20 1985-09-18 International Business Machines Corporation Régulation d'une pompe péristaltique
EP0156974A2 (fr) * 1983-12-08 1985-10-09 Cordis Corporation Régulateur de débit à trois conditions de fonctionnement pour fluides corporels
DE3441893A1 (de) * 1984-11-16 1986-05-28 Walter Küsnacht Beck Verfahren und vorrichtung zum absaugen von sekretfluessigkeit aus einer wunde
WO1986006964A1 (fr) * 1985-05-21 1986-12-04 Coopervision, Inc. Cassette pour irrigation et aspiration chirurgicales
GB2176717A (en) * 1985-06-25 1987-01-07 Cobe Lab Fluid flow transfer and apparatus and methods associated therewith

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3812855A (en) * 1971-12-15 1974-05-28 Surgical Design Corp System for controlling fluid and suction pressure
EP0037992A1 (fr) * 1980-04-14 1981-10-21 Thomas Jefferson University Liquide cérébrospinal, méthode de fabrication d'un tel liquide et appareil destiné à sa mise en oeuvre
EP0156974A2 (fr) * 1983-12-08 1985-10-09 Cordis Corporation Régulateur de débit à trois conditions de fonctionnement pour fluides corporels
EP0154681A1 (fr) * 1983-12-20 1985-09-18 International Business Machines Corporation Régulation d'une pompe péristaltique
DE3441893A1 (de) * 1984-11-16 1986-05-28 Walter Küsnacht Beck Verfahren und vorrichtung zum absaugen von sekretfluessigkeit aus einer wunde
WO1986006964A1 (fr) * 1985-05-21 1986-12-04 Coopervision, Inc. Cassette pour irrigation et aspiration chirurgicales
GB2176717A (en) * 1985-06-25 1987-01-07 Cobe Lab Fluid flow transfer and apparatus and methods associated therewith

Cited By (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6986753B2 (en) * 1998-05-21 2006-01-17 Buivision Constant ocular pressure active infusion system
CN100479870C (zh) * 2001-11-30 2009-04-22 博士伦公司 使用流量计控制系统的收集容器
WO2003047653A1 (fr) * 2001-11-30 2003-06-12 Bausch & Lomb Incorporated Detecteur et regulateur de debit d'aspiration
EP1642604A1 (fr) * 2001-11-30 2006-04-05 Bausch & Lomb Incorporated Réservoir de collecte s'utilisant avec un régulateur de débit
AU2002357750B2 (en) * 2001-11-30 2007-03-15 Bausch & Lomb Incorporated Aspiration flow meter and control
WO2003047652A1 (fr) * 2001-11-30 2003-06-12 Bausch & Lomb Incorporated Reservoir de collecte s'utilisant avec un regulateur de debit
CN100479871C (zh) * 2001-11-30 2009-04-22 博士伦公司 抽吸流量计及控制
US8246580B2 (en) 2005-06-21 2012-08-21 Novartis Ag Aspiration control via flow or impedance
JP2008543488A (ja) * 2005-06-21 2008-12-04 アルコン,インコーポレイティド 吸引制御
JP2008543487A (ja) * 2005-06-21 2008-12-04 アルコン,インコーポレイティド 流量監視による吸引制御
AU2006262932B2 (en) * 2005-06-21 2012-03-15 Alcon Inc. Aspiration control via flow or impedance
EP1893250A4 (fr) * 2005-06-21 2009-04-29 Alcon Inc Regulation de l'aspiration par surveillance du flux ou de l'impedance
US8545198B2 (en) 2005-11-17 2013-10-01 Novartis Ag Surgical cassette
US7775780B2 (en) 2006-01-24 2010-08-17 Alcon, Inc. Surgical cassette
US8079836B2 (en) 2006-03-01 2011-12-20 Novartis Ag Method of operating a peristaltic pump
JP2009530048A (ja) * 2006-03-20 2009-08-27 アルコン,インコーポレイティド 多領域の流体室を有する手術カセット
US8006570B2 (en) 2006-03-29 2011-08-30 Alcon, Inc. Non-invasive flow measurement
US8251944B2 (en) 2006-03-29 2012-08-28 Novartis Ag Surgical system having a cassette with an acoustic coupling
US8343100B2 (en) 2006-03-29 2013-01-01 Novartis Ag Surgical system having a non-invasive flow sensor
US8465467B2 (en) 2006-09-14 2013-06-18 Novartis Ag Method of controlling an irrigation/aspiration system
EP1935440A3 (fr) * 2006-12-18 2008-09-03 Alcon, Inc. Système et procédé de contrôle de débit de fluide dans une cuve d'aspiration
JP2008149148A (ja) * 2006-12-18 2008-07-03 Alcon Inc 吸引室内の流体流を制御するためのシステム及び方法
WO2010059760A1 (fr) * 2008-11-21 2010-05-27 Bausch & Lomb Incorporated Appareil et procédé de commande d'une source de vide pour établissement d'un écoulement de fluide
US8439874B2 (en) 2008-11-21 2013-05-14 Bausch & Lomb Incorporated Apparatus and method for controlling a vacuum source to establish fluid flow
DE102010010336A1 (de) * 2010-03-04 2011-09-08 Geuder Ag Steuer-/Versorgungseinheit zum Betreiben eines medizinischen Handgeräts
DE102010010335A1 (de) * 2010-03-04 2011-09-08 Geuder Ag Steuer-/Versorgungseinheit zum Betreiben eines medizinischen Handgeräts und dazu passende Kassette
CN104168933A (zh) * 2012-03-12 2014-11-26 弗雷泽纽斯医疗保健控股有限公司 用于从液体中排出气体的装置和方法
US11110218B2 (en) 2012-09-06 2021-09-07 D.O.R.C. Dutch Ophthalmic Research Center (International) B.V. Surgical cartridge, pump and surgical operating machine
US10285854B2 (en) 2013-12-17 2019-05-14 Medical Instrument Development Laboratories, Inc. Integrated oclular fluid management system
US20150164690A1 (en) * 2013-12-17 2015-06-18 Medical Instrument Development Laboratories, Inc. Diaphragm-position-controlled, multi-mode ocular fluid management system and method
WO2015094736A1 (fr) * 2013-12-17 2015-06-25 Medical Instrument Development Laboratories, Inc. Système de gestion de fluide oculaire multi-mode à position de membrane commandée et procédé
US10022268B2 (en) * 2013-12-17 2018-07-17 Medical Instrument Development Laboratories, Inc. Diaphragm-position-controlled, multi-mode ocular fluid management system and method
DE102016201297B3 (de) 2016-01-28 2017-03-30 Carl Zeiss Meditec Ag Ophthalmochirugisches System
JP2019022715A (ja) * 2016-01-28 2019-02-14 カール・ツアイス・メディテック・アーゲー 眼科手術システム
US10639196B2 (en) 2016-01-28 2020-05-05 Carl Zeiss Meditec Ag Ophthalmosurgical system
US10722619B2 (en) 2016-01-28 2020-07-28 Carl Zeiss Meditec Ag Method for operating an ophthalmosurgical system
JP2017131649A (ja) * 2016-01-28 2017-08-03 カール・ツアイス・メディテック・アーゲー 眼科手術システム
CN109922764A (zh) * 2016-11-03 2019-06-21 This股份公司 无菌的文丘里吸出
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