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WO1996011027A1 - Dispositif d'administration de liquides chauffes a un patient a l'aide d'une injection intraveineuse - Google Patents

Dispositif d'administration de liquides chauffes a un patient a l'aide d'une injection intraveineuse Download PDF

Info

Publication number
WO1996011027A1
WO1996011027A1 PCT/EP1995/003895 EP9503895W WO9611027A1 WO 1996011027 A1 WO1996011027 A1 WO 1996011027A1 EP 9503895 W EP9503895 W EP 9503895W WO 9611027 A1 WO9611027 A1 WO 9611027A1
Authority
WO
WIPO (PCT)
Prior art keywords
flexible tube
dissipative element
delivery
patient
power supply
Prior art date
Application number
PCT/EP1995/003895
Other languages
English (en)
Inventor
Michele Gazzano
Original Assignee
Cerrutti, Aldo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerrutti, Aldo filed Critical Cerrutti, Aldo
Publication of WO1996011027A1 publication Critical patent/WO1996011027A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance

Definitions

  • the present invention relates to a device for administering to a patient warmed liquids such as plasma, physiological and medical fluids, etc..
  • the blood is usually stored at about 4°C, while the physiological and medical fluids are stored at room temperature.
  • the patient's blood is mixed with the infusion fluids and is cooled by these latter.
  • the patient is often under anhestesia or unconscious so that the organism is unable to activate the usual defensive reactions with a consequent state of general hypothermia which in addition to being uncomfortable for the patient can severely interfere with other clinical aspects such as the reaction to drugs, hemorrhage, the cardiac rhythm, etc.
  • EP-A-0 528 437 discloses an electric heater surrounding a section of the delivery line for pulsed heating the fluid at a place of the line, with the energizing duty cycle that is controlled by a monitoring unit incorporating a microprocessor and connected to temperature sensors.
  • EP-A-0 501 179 provides for a U-shaped container in which a medical fluid flows, connected to a source of electric energy for maintaining a constant temperature of the fluid.
  • EP-A-0 247 989 provides for a disposable tubular heat exchanger that is supplied with a warming fluid.
  • DD 213 352 discloses a blood warming equipment comprising a heater element having good heat conductivity and following the path of the blood flow in a blood-heating bag.
  • Additional known devices provide for local heating of blood or plasma in a bag by using microwaves (EP-A-0 307 895) , or by means of electrically heated plates, with a portion of the delivery tube arranged to form labyrinthine passageways and in relation of thermal exchange with the plates (EP-A-0 292 076) , or for the injection of sterilized fluids (FR-A-2 403 082) .
  • Another known device such as that disclosed in EP-A-0 256 653 provides for a distributed heating by using a heat exchanger having an inner tube for the blood flow and an outer tube providing a flow path for a heating fluid.
  • a distributed warming system comprising a three-way delivery tube, i.e. having a central circular portion in which the fluid to be infused flows and two separate semi-annular portions for the flow ⁇ delivery and return, respectively) of a heating liquid such as water at about 40°.
  • the above distributed warming system is capable of preventing a thermal shock to the patient since the warming can be controlled up to the patient's arm, i.e. at the entrance into the body.
  • the systems providing a circulation of a liquid in thermal exchange relationship with the fluid to be infused require a pump for keeping the liquid circulating, usually water.
  • Such a pump is noisy and cumbersome and moreover requires a periodic maintenance, including the replacement of the heating water even for sanitary reasons, and is nevertheless subjected to malfunctions .
  • the object of the present invention is to overcome the above mentioned limitations and shortcomings, and more particularly to provide a device for administering to a patient warmed liquids such as plasma, physiological and medical fluids and the like, wherein the temperature of the liquid is easily and precisely controlled, without appreciably increasing the diameter of the delivery tube, or increasing its stiffness. Moreover the construction of the device is simple and not expensive, and its working is reliable.
  • Fig. 1 schematically illustrates the overall construction of the system for administering warmed liquids according to the invention
  • Fig. 2 is a more detailed partial cross-section of an embodiment of the device according to the inven ion,*
  • Fig. 3 is a cross-section view along lines III-III of Fig. 2;
  • Fig. 4 illustrates a connector for the electrical coupling to the heating means,*
  • Fig. 5 illustrates another embodiment of the device according to the invention.
  • Fig. 6 is a cross-section view of another embodiment of the delivery flexible tube.
  • the illustrated administering system comprises a container 1, e.g. a bottle or a plastic bag containing the infusion fluid, for example a physiologic solution, plasma or other fluid to be injected, which is mounted on a holder 2, such as for example a vertical metal post resting on a base 3.
  • a container e.g. a bottle or a plastic bag containing the infusion fluid, for example a physiologic solution, plasma or other fluid to be injected
  • a holder 2 such as for example a vertical metal post resting on a base 3.
  • the drip chamber 4 allows a visual checking of the flow rate and its outlet is connected to delivery flexible tube or a hose 7, usually of plastic material, extending up to the patient's bed and connected to a needle 6 inserted into a vein of the patient.
  • the plastic delivery flexible tube 7 is made for example of PVC and/or polyurethane, and has a length of a couple of meters. A relatively rigid portion of the tube (not shown) can be employed for joining together flexible tubes 5 and 7.
  • electrical heating means in form of one or more distributed dissipative elements (i.e. capable of turning electrical power into heat) .
  • at least one electrical conductive means or conductor 12 is embedded or incorporated within the inner surface of the plastic wall 14 of the flexible tube 7.
  • the above conductor is completely merged within the wall 14 of the delivery flexible tube, however the conductor could be only partially embedded within the wall 14, or in case merely made to adhere to the inner surface of the delivery flexible tube (see Fig. 6) , and suitably covered by a protective coating of plastic material.
  • the electrical (linear) resistivity can be in the order of a few ⁇ /cm, and is a function of the cross-section area of the conductor (s) 12.
  • the overall required electric power is not greater than 200 Watts, aven in case the fluid to be heated is just thawed blood.
  • the conductor 12 is a metal one, having a flat cross-section and substantially laid along an helical path.
  • the conductor 12 forms two helical paths each having one end connected together (i.e. shortcircuited) inside the flexible tube at 12A, with the other ends being electrically connected to the power supply means 9.
  • dissipative elements are biologically compatible and adapted to realize distributed dissipative means, such as for example a metal foil, a deposition of metallic (or at least conductive) material, etc.
  • delivery flexible tube 7 is formed by extrusion of plastic material .
  • a further embodiment of the dissipative means provides for two low-resistance electrical conductors that are substantially parallel to each other, and concentrated resistive elements, e.g. of resistive inks or other material having an appreciable resistivity are connected between said two conductors at regular intervals, with all such conductors and resistive elements being completely embedded within the thickness of the wall 14 of the flexible tube 7.
  • concentrated resistive elements e.g. of resistive inks or other material having an appreciable resistivity
  • the power supply means 9 is capable of applying to the distributed heater formed by the conductor (s) 12 a voltage that varies with time, preferably -a sinusoidal voltage having an amplitude not higher than 20-30 V.
  • the power supply means 9 includes a male connector member 11A mechanically fastened to the tube 7 and provided with at least two terminals 31, 32 that are electrically connected to the ends of conductor (s) 12.
  • a corresponding female connector member 11B is fastened to the control unit 10 or in case to the rod 2 , and is connected to the male connector 11A, as shown in Figure 2.
  • Connector 11A can include additional terminals, shown at 33, 34, and 35, 36 for being connected to additional sensors that might be located along the delivery flexible tube 7, as will be illustrated later on.
  • the delivery flexible tube 7 according to the invention can further incorporate auxiliary electrical conductors (22A, 22B in Figure 3) for temperature sensors 21 and 22, preferably thermocouples located upwards and downwards the heater.
  • the two sensors 21 and 22 are connected to the control unit 10 that in turn, using known techniques and a microprocessor or the like, adjusts the supplied power for keeping the fluid output temperature within a prescribed range.
  • the control unit 10 is connected through a cable 18 and a plug 19 to the mains and preferably further includes a keybord 26 and a display 25.
  • the voltage control can change the amplitude of the supplying voltage, or even supply a portion of a sinusoidal waveform by using tyristors or similar controlled switching devices, or generate a train of voltage pulses having a duration - e.g. a duty cycle - that is variable, and so on.
  • the flexible tube-connector assembly is realized as an integral and sterilized component to be disposed after use.
  • the power tranfer takes place inductively and the means 9 includes a transformer with a primary winding connected to the unit 10 and the secondary winding electrically connected to the distributed dissipative element 12.
  • such windings are in form of coaxial coils wound on substantially cylindrical supports that are not shown, with the secondary winding 16 surrounding a portion of the delivery flexible tube 7 and secured thereto, in case in a not permanent manner.
  • the coil is slightly forced over the tube in correspondence of external contact-s (not shown) leading to the conductor 12.
  • the coil 15 of the primary winding has an inner diameter substantially corresponding to the outer diameter of the secondary coil 15, still allowing an axial movevent in respect of the former.
  • the support of this coil 15 is provided with a lower supporting portion having a reduced diameter to support the coil 15 of the primary winding together with the tube 7 secured thereto.
  • the tube-coil assembly can be formed as a single inseparable component to be disposed of after a predetermined number of uses.
  • the device of the invention through relatively simple and easy calibration and data storage operations, can be used for determining the flow rate of the injected fluid from the power supplied to the fluid under steady conditions.
  • the device of the invention does not increase the filling volume, i.e. that portion of the fluid which remains in the tube at the end of the infusion) , ad eliminates any risk of thermal shock since it allows for a progressive and controlled warm up of the fluid to a desired temperature at the point the fluid enters the patient's circulatory system.
  • the delivery flexible tube 7 substantially maintains its flexibility and the original diameter, with an additive cost which is in practice negligible.
  • the device of the invention eliminates all moving parts and allows an extremely precise and quick control of the temperature of the fluid being injected.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Ce dispositif d'administration de liquides chauffés à un patient, à l'aide d'une injection intraveineuse, comprend un tube d'apport (7) flexible conçu pour être chauffé de manière répartie au moins sur une longueur de celui-ci. Un élément (12) dissipatif électriquement est encastré dans la paroi (14) du tube (7) flexible et est relié à des moyens (9) d'alimentation d'énergie destinés à appliquer audit élément (12) une tension qui varie avec le temps en réponse à la température du liquide en cours d'injection. En outre, le tube flexible peut incorporer des conducteurs (22A, 22B) électriques auxiliaires connectés à des capteurs (21, 22) de température placés le long du tube. L'élément (12) dissipateur peut être alimenté soit par l'intermédiaire d'un connecteur (11A, 11B), soit de manière inductive par l'intermédiaire d'un transformateur.
PCT/EP1995/003895 1994-10-05 1995-10-02 Dispositif d'administration de liquides chauffes a un patient a l'aide d'une injection intraveineuse WO1996011027A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI94A002029 1994-10-05
ITMI942029A IT1270126B (it) 1994-10-05 1994-10-05 Dispositivo per somministrare liquidi riscaldati ad un paziente per via endovena

Publications (1)

Publication Number Publication Date
WO1996011027A1 true WO1996011027A1 (fr) 1996-04-18

Family

ID=11369653

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1995/003895 WO1996011027A1 (fr) 1994-10-05 1995-10-02 Dispositif d'administration de liquides chauffes a un patient a l'aide d'une injection intraveineuse

Country Status (2)

Country Link
IT (1) IT1270126B (fr)
WO (1) WO1996011027A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1066844A1 (fr) * 1999-07-06 2001-01-10 Respiratory Support Products Inc. Dispositif de chauffage du fluide de perfusion pour intraveineuse par chauffage du fluide dans le tube de perfusion
US6641556B1 (en) 1999-07-06 2003-11-04 Respiratory Support Products, Inc. Intravenous fluid heating system
EP1779883A1 (fr) * 2005-10-27 2007-05-02 Hotwatch ApS Appareil portatif pour le chauffage des fluides intraveineux
EP1624910A4 (fr) * 2003-05-01 2010-12-22 Thermics Llc Procede et systeme de chauffage d'un liquide
DE102014105808A1 (de) * 2014-04-24 2015-10-29 Olympus Winter & Ibe Gmbh Vorrichtung zum Erwärmen einer dem menschlichen Körper zuzuführenden Flüssigkeit
EP1750793A4 (fr) * 2004-05-28 2017-11-15 Carefusion Corporation Regulation de l'ecoulement, detection du gaz et extraction du gaz present dans un systeme d'administration de fluide intraveineux.
WO2019023047A1 (fr) 2017-07-27 2019-01-31 Scott Norman Ensemble de tube patient chauffé

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH198839A (de) * 1937-10-30 1938-07-15 Alois Schuler Vorrichtung zum Einführen von flüssigen Stoffen in den menschlichen oder tierischen Körper.
DE2454349A1 (de) * 1973-11-15 1975-07-03 Rhone Poulenc Sa Biegsames heizrohr
US5319170A (en) * 1992-10-20 1994-06-07 Belmont Instrument Corporation Induction fluid heater utilizing a shorted turn linking parallel flow paths

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH198839A (de) * 1937-10-30 1938-07-15 Alois Schuler Vorrichtung zum Einführen von flüssigen Stoffen in den menschlichen oder tierischen Körper.
DE2454349A1 (de) * 1973-11-15 1975-07-03 Rhone Poulenc Sa Biegsames heizrohr
US5319170A (en) * 1992-10-20 1994-06-07 Belmont Instrument Corporation Induction fluid heater utilizing a shorted turn linking parallel flow paths

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1066844A1 (fr) * 1999-07-06 2001-01-10 Respiratory Support Products Inc. Dispositif de chauffage du fluide de perfusion pour intraveineuse par chauffage du fluide dans le tube de perfusion
US6641556B1 (en) 1999-07-06 2003-11-04 Respiratory Support Products, Inc. Intravenous fluid heating system
EP1624910A4 (fr) * 2003-05-01 2010-12-22 Thermics Llc Procede et systeme de chauffage d'un liquide
EP1750793A4 (fr) * 2004-05-28 2017-11-15 Carefusion Corporation Regulation de l'ecoulement, detection du gaz et extraction du gaz present dans un systeme d'administration de fluide intraveineux.
EP1779883A1 (fr) * 2005-10-27 2007-05-02 Hotwatch ApS Appareil portatif pour le chauffage des fluides intraveineux
WO2007048414A1 (fr) 2005-10-27 2007-05-03 Hotwatch Aps Dispositif portable pour chauffer des fluides intraveineux
DE102014105808A1 (de) * 2014-04-24 2015-10-29 Olympus Winter & Ibe Gmbh Vorrichtung zum Erwärmen einer dem menschlichen Körper zuzuführenden Flüssigkeit
WO2019023047A1 (fr) 2017-07-27 2019-01-31 Scott Norman Ensemble de tube patient chauffé
EP3658216A4 (fr) * 2017-07-27 2021-07-21 Neonatal Product Group, Inc. Ensemble de tube patient chauffé

Also Published As

Publication number Publication date
ITMI942029A0 (it) 1994-10-05
IT1270126B (it) 1997-04-28
ITMI942029A1 (it) 1996-04-05

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