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WO1996016690A1 - Catheter dote d'un support de cloison destine a empecher son affaissement - Google Patents

Catheter dote d'un support de cloison destine a empecher son affaissement Download PDF

Info

Publication number
WO1996016690A1
WO1996016690A1 PCT/US1995/014865 US9514865W WO9616690A1 WO 1996016690 A1 WO1996016690 A1 WO 1996016690A1 US 9514865 W US9514865 W US 9514865W WO 9616690 A1 WO9616690 A1 WO 9616690A1
Authority
WO
WIPO (PCT)
Prior art keywords
catheter
length
coil spring
passageway
proximal end
Prior art date
Application number
PCT/US1995/014865
Other languages
English (en)
Inventor
Keith Joseph Mcwha
Joseph J. Gregg
Original Assignee
Becton, Dickinson And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton, Dickinson And Company filed Critical Becton, Dickinson And Company
Publication of WO1996016690A1 publication Critical patent/WO1996016690A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0009—Making of catheters or other medical or surgical tubes
    • A61M25/0014—Connecting a tube to a hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M25/005—Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids

Definitions

  • This invention relates to a device for averting the collapse of the walls of a catheter, and more particularly, to a catheter having wall support to prevent collapse or kinking and being adaptable for use with standard medical adaptor and delivery instruments and accessories
  • Catheters are typically elongate tubes formed from medical grade plastics made as polyethylene, polyimide, or even nylon, which define fluid carrying ducts for transporting a medicament from a delivery instrument to body tissue They are typically introduced into the body cavity through the lumen of a needle or introducer device already pierced into the body
  • a catheter is found in providing continuous regional anesthesia, and is exemplified, for instance, by the use of epidural catheters to deliver anesthesia to the epidural space of a patient Catheters are also used for analgesic purposes to provide sustained pain relief following a surgical procedure Here, the catheter is kept in place following the procedure and analgesic medicaments administered intermittently according to the needs of the patient
  • catheters such as intended for epidural anesthesia can be formed from a stiff mate ⁇ al such as nylon or a soft mate ⁇ al such as polyurethane Both types of mate ⁇ als present certain advantages and certain drawbacks In a studv conducted by M Johr, F A Hess, S Balogh and H Gerber, "The choice of the epidural catheter stiff or soft 7 " (Regional Anesthesia. Volume 17, No 3S, May-June 1992 Supplement),
  • kinking also frequently occurs at the proximal end of the catheter when, for instance, a standardized medical connector such as a Tuohy- Borst adapter is attached for mating with a medical deliver/ device such as a syringe
  • the Tuohy-Borst adapter includes a gasket portion which applies pressure about the circumference of the catheter The pressure exerted at or near the proximal end can cause the catheter walls to collapse upon themselves so as to constrict if not eliminate flow of the medicament from the medical delivery device through the catheter.
  • the coil is wound in a section at or near the distal tip of the catheter, while in the '674 patent it appears that the wire coil is displaced along substantially the entire length of the catheter.
  • the '022 patent further employs a "durable catheter" segment proximally of the wire coil catheter segment which has a stainless steel tube formed of a flat wire coil that surrounds the length of the tube A similar approach is taken by Arrow International, Inc. in its "Flex-
  • Tip PlusTM epidural catheter, which features a catheter having a tightly wound wire coil in the fluid duct substantially along the entire length of the catheter and is sold with its own proprietary adaptor device in lieu of a standardized adaptor such as a Tuohy-Borst adaptor. While serving to minimize catheter diameters somewhat and address certain kinking problems along the length of the catheter, none of these approaches is entirely satisfactory.
  • a first problem is that it is believed that the presence of a metallic component throughout substantially the entire length of the catheter contributes to difficulties with paraesthesia in the patient.
  • a further problem is that the presence of a coil along the entire length of a catheter typically necessitates that the catheter be formed with an open distal end
  • Closed-ended catheters are typically provided with circumferential ports adjacent the distal end of the catheter for emitting the fluid medicament into the bodv tissue Practitioners have found that with the latter construction, a more uniform flow is provided and that it is easier to direct the flow of anesthetic to a specific point so as to provide a deeper and more precise block
  • open-ended catheters mav be more traumatic to tissue and. hence, could be more difficult and more painful to place in the tissue than close-ended catheters See, for instance, S Michael, M.N.
  • the catheter may be formed from a soft material such as polyurethane to minimize traumatic effects to the body
  • the catheter features a proximal end adapted to be retained by a medical adapter such as a Tuohy- Borst adapter together with a major length adapted for insertion into the body cavity of a patient
  • the proximal end of the catheter may be configured to resist the pressures exerted by the adapter so as to prevent collapsing or kinking of the catheter
  • a section of coiled wire tubing may be fixedly bonded to the catheter such as by chemical adhesives, ultrasonic welding, heat welding (heat staking) or RF welding
  • the coil is disposed about the interior of the catheter substantially adjacent
  • the diameter of catheter wall section to be strengthened can be configured apart from the rest of the catheter so as to compensate for any diametral or flow constrictions imposed by the presence of the coil about the outer catheter duct.
  • the coil may be formed about the circumference of the catheter, or it may be incorporated as part of the medical adaptor.
  • the remaining length of the catheter may be strengthened by structuring techniques to prevent collapsing and/or kinking during use.
  • the catheter may be strengthened by structuring the interior with a profile to prevent kinking problems along the length.
  • the profile can constitute forming the interior of the catheter with rib elements.
  • the catheter may be structured with a form-specific profile or cross-section such as a star-shaped cross-section.
  • This approach prevents the hindrances of extraneous inserts in the flow of fluid. Because the structuring is largely parallel to the flow path, the probability of turbulent flow is significantly reduced.
  • a closed-ended distal tip may be readily incorporated and circumferential ports provided for the exit of fluids.
  • Fig. 1 depicts a longitudinal cross-sectional view of one embodiment of a catheter according to the present invention.
  • Fig. 2 is a cross-sectional view taken along line 2-2 of Fig. 1 ;
  • Fig. 3 depicts a second longitudinal cross-sectional view of the embodiment of Fig. 1 shown in conjunction with a medical adaptor device;
  • Fig. 4 is a side view of a catheter wall support device as employed in the present invention.
  • Fig. 5 is an end view of the catheter wall support device depicted in Fig. 4;
  • Fig. 6 depicts the catheter of the present invention incorporating a wider-diameter proximal end to accommodate a catheter wall support device;
  • Fig. 7 illustrates a structured cross-section for the interior duct of the catheter of the present invention.
  • Figs. 1-7 depict one embodiment of an anti-kinking catheter 10 in accordance with the present invention.
  • the catheter 10 includes a distal end 12 having a closed end 20, a proximal end 14 having a catheter wall support device 22, and a major length 15 is adapted for insertion into a body cavity during a medical procedure.
  • the catheter 10 may be formed from any number of medical grade materials such as nylon.
  • the catheter 10 is formed from a soft material such as polyurethane so as to minimize traumatic effect to the body and provide the practitioner with a clear view of fluid flow through the catheter 10.
  • a plurality of circumferential side port openings 18 may be formed at or about the distal end 12 of the catheter to provide for the exit of fluid introduced via the proximal end 22 of the catheter
  • the outside diameter (“OD") of the catheter 10 may be dimensioned in any of the standard medical gauges most appropriate or readily used for the intended application. For instance, for an epidural catheter, the OD can be established, as per the conventional sizing typically used by practitioners, to 19 gauge (approximately 0 043"), 20 gauge (approximately 0.035"), or even 24 gauge (approximately 0.022").
  • a catheter wall support device 22 is incorporated at the proximal end 14 of the catheter and is snugly retained about the fluid duct 40, which is defined by an inner diameter "y"
  • the coil spring 22 can be retained to the catheter, inter alia, by chemical adhesives, ultrasonic welding, heat staking or RF welding
  • the support device 22 may have a length "x" of between, for example, 1/8" to 1/2". depending upon the type of adapter such as a Tuohy- Borst adapter 30, which is attached to the proximal end 14 A Tuohy-Borst adapter 30, such as depicted in Fig.
  • a gasket portion 32 having a plurality of threads 36 engageable by a nut 34 actuated by a knob 38
  • knob 38 is rotated, nut 34 is advanced distally along the threads 36 to exert pressure upon the gasket 32.
  • the support device 22 will prevent collapse and/or occlusion of the catheter when the force is applied by the gasket 32, so as not to impede fluid flow through the catheter 10
  • the length "x" of the coil spring 22 should be matched to and be at least as long as the length 32 of the adaptor gasket, lest a portion of the gasket be allowed to exert force upon an unsupported portion of the catheter to cause occlusion or kinking in a manner previously described.
  • the support device 22 may be formed as coil spring, as best depicted in Figs. 4 and 5
  • the spring 22 may be formed, for instance, from AISI Type 304 stainless steel.
  • the spring 22 may be wound from a wire having a diameter "a" of about 0 003" to form a plurality of active coil turns 42.
  • the numbers of active coil turns 42 can be, for instance, 25.
  • the coil spring may define an outer diameter "d" of about 0 016" ⁇ 0 001 " and an inner diameter "c" of about 0 010"
  • the spring 22 may be bonded to the catheter 10 with various medical grade adhesives
  • the spring 22 is heat stake welded or RF welded within duct 40 about the interior of the catheter 10, lessening the possibility that a chemical adhesive bonding element can adversely react with the medicaments introduced through the catheter 10
  • the spring 22 will thus be fixedly secured to the catheter so as to bond the coil spring 22 to the catheter 10
  • the catheter material may flow around the spring coils 42, thereby embedding the coil within the catheter wall, such that the catheter duct 40 will be substantially uniform along its entire length
  • the spring 22 is better able to distribute stresses and forces and can largely avoid the creation of a stress concentrator (for instance, at the interface between the end of the coil and the catheter itself) which could lead to breakage.
  • the coil spring is disposed only adjacent the proximal end of a catheter 10 and in particular, only at the location subject to retention by the adapter 30, so as to provide anti-kink protection in the area where most needed.
  • problems caused by a coil spring disposed throughout the entire length of the catheter in accordance with prior teachings in the art such as traumatic effects, paraesthesia, or the ability to form a closed-end catheter with good strength properties, are largely avoided because no metal is present in the substantial length of the catheter.
  • the proximal end 14 of the catheter can be further minimized, if not completely eliminated, by forming the proximal end 14 of the catheter slightly wider than the rest of the length of the catheter in order to accommodate the diametral width of the coil spring 22 therein.
  • the larger catheter width provides for a substantially smooth interface between the coil spring and the remainder of the duct 40 of the catheter 10.
  • fluid is free to flow without interruption at a stepped interface between the spring and the catheter duct, reducing the instance of turbulent flow characteristics and contributing to laminar flow throughout the length of the conduit of the catheter 10.
  • the spring 22 can be appropriately dimensioned so as to be incorporated about the outside circumference of the catheter 10, rather than in the interior such as within duct 40.
  • the coil can be affixed to the catheter such as by heat welding or RF welding in a manner previously described, so as to enjoy the benefits previously noted. Note here that the presence of an intrusive element within the flow duct is completely obviated.
  • the spring 22 can be incorporated as part of the adaptor 30 itself, for instance, at or about the gasket portion 32, with the proximal end of catheter 10 engaged within the gasket 32/co ⁇ l spring 22
  • the presence of the sp ⁇ ng 22 about the outside surface of the catheter 10 substantially prevents constriction of the catheter in a manner previously noted
  • the length of the catheter 10 and in particular, the major length 15 comprising the portion to be manipulated and/or inserted into the body cavity can be provided with a profiling or structu ⁇ ng treatment along the duct 40 so as to enhance the overall anti-kinkmg properties of the catheter
  • the structuring treatment strengthens the catheter 10 against kinking or occlusion problems while at the same time permitting a softer material to be employed in forming the catheter
  • the catheter 10 may be extruded so as to include a profiling treatment such as longitudinal ribs running along the length of the catheter, either outside the catheter or, so as to minimize trauma to the patient, forming ribs on the interior cross-section of the catheter
  • the catheter 10 may be formed or extruded with a shaped duct cross-section designed to enhance the catheter's ability to resist occlusion if bent
  • the catheter can be formed with a star-shaped cross- section configuration Even if the catheter 10 is bent along its length, the interspaces 60 defined between the star points (or ribs, if so configured) will permit fluid to pass through the duct 40 to the distal end 12 Moreover, because the material can be chosen for its clarity properties, practitioners are still provided with an unimpeded view of the medicament flowing through the catheter
  • the catheter according to the present invention addresses many of the drawbacks exemplified by the prior art approaches
  • the catheter displays anti-kinkmg properties substantially along its entire length, while not obscuring the view of the practitioner during use and permitting the catheter to be formed from a relatively soft mate ⁇ al and with a closed ended construction so as to minimize traumatic effects to the patient
  • the construction also contributes to overall strength and integrity of the catheter along its entire length
  • laminar flow is provided over the length of the duct, permitting the practitioner to better provide a more precise and effective block

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

Cathéter doté d'un support de cloison destiné à empêcher l'occlusion ou l'entortillement, en particulier dus à la constriction provoquée par un adaptateur médical fixé à l'extrémité proximale dudit cathéter. Ledit cathéter peut être constitué d'un matériau mou tel que du polyuréthanne de manière à ce que les effets traumatiques sur le corps soient réduits à un minimum. Un ressort à boudin est placé autour du passage du cathéter à l'extrémité proximale. La longueur du ressort à boudin correspond de préférence à la longueur du cathéter soumis à la constriction par l'adaptateur, ce qui permet de pouvoir toujours bien voir le fluide à travers le cathéter tout en fournissant un support anti-occlusion là où il est le plus nécessaire. Si désiré, la plus grande partie de la longueur du cathéter peut être soumise à un traitement de maintien de structure ou renforcement de manière à obtenir une résistance à l'entortillement sur toute la longueur du cathéter tout en conservant les avantages d'un matériau mou.
PCT/US1995/014865 1994-11-29 1995-11-15 Catheter dote d'un support de cloison destine a empecher son affaissement WO1996016690A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34610194A 1994-11-29 1994-11-29
US08/346,101 1994-11-29

Publications (1)

Publication Number Publication Date
WO1996016690A1 true WO1996016690A1 (fr) 1996-06-06

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5947940A (en) * 1997-06-23 1999-09-07 Beisel; Robert F. Catheter reinforced to prevent luminal collapse and tensile failure thereof
WO2001070322A1 (fr) * 2000-03-24 2001-09-27 Stephen Brushey Catheter pour anesthesie
EP1428545A1 (fr) * 2002-12-11 2004-06-16 Abbott Laboratories Vascular Enterprises Limited Cathéter
US7438711B2 (en) 1999-07-19 2008-10-21 I-Flow Corporation Catheter for uniform delivery of medication
US7547302B2 (en) 1999-07-19 2009-06-16 I-Flow Corporation Anti-microbial catheter
US7569045B2 (en) 1999-07-19 2009-08-04 I-Flow Corporation Catheter for uniform delivery of medication
WO2009097289A1 (fr) * 2008-01-30 2009-08-06 Becton, Dickinson And Company Cathéters résistant à l'occlusion
US20090227987A1 (en) * 2008-03-07 2009-09-10 Howard Singer Device for treating pneumothorax, tension pneumothorax, pleural effusion, and hemothorax in neonates
EP2679268A1 (fr) * 2012-06-27 2014-01-01 Peak Medical Ltd. Système de cathéter de perfusion
US9789279B2 (en) 2014-04-23 2017-10-17 Becton, Dickinson And Company Antimicrobial obturator for use with vascular access devices
US9956379B2 (en) 2014-04-23 2018-05-01 Becton, Dickinson And Company Catheter tubing with extraluminal antimicrobial coating
US10232088B2 (en) 2014-07-08 2019-03-19 Becton, Dickinson And Company Antimicrobial coating forming kink resistant feature on a vascular access device
US10376686B2 (en) 2014-04-23 2019-08-13 Becton, Dickinson And Company Antimicrobial caps for medical connectors
US10493244B2 (en) 2015-10-28 2019-12-03 Becton, Dickinson And Company Extension tubing strain relief
US11357962B2 (en) 2013-02-13 2022-06-14 Becton, Dickinson And Company Blood control IV catheter with stationary septum activator

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1933802A1 (de) * 1968-06-28 1970-01-02 Sherwood Medical Ind Inc Herzkatheter
US4634432A (en) * 1985-05-13 1987-01-06 Nuri Kocak Introducer sheath assembly
FR2607707A1 (fr) * 1986-12-08 1988-06-10 Lpi Embase amovible pour catheter et catheter adapte a celle-ci
US4790831A (en) * 1987-03-30 1988-12-13 Baxter Travenol Laboratories, Inc. Torque-control catheter
FR2655548A1 (fr) * 1989-12-11 1991-06-14 Cleef Jean Francois Van Catheter a parois non lisses, catheter a parois moulurees.
EP0440426A1 (fr) * 1990-01-30 1991-08-07 Bard Connaught Manchette hémostatique pouvant être utilisée avec un cathéter
WO1992007507A1 (fr) * 1990-10-29 1992-05-14 Boston Scientific Corporation Fil transformable en fil de guidage-catheter a extremite souple

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1933802A1 (de) * 1968-06-28 1970-01-02 Sherwood Medical Ind Inc Herzkatheter
US4634432A (en) * 1985-05-13 1987-01-06 Nuri Kocak Introducer sheath assembly
FR2607707A1 (fr) * 1986-12-08 1988-06-10 Lpi Embase amovible pour catheter et catheter adapte a celle-ci
US4790831A (en) * 1987-03-30 1988-12-13 Baxter Travenol Laboratories, Inc. Torque-control catheter
FR2655548A1 (fr) * 1989-12-11 1991-06-14 Cleef Jean Francois Van Catheter a parois non lisses, catheter a parois moulurees.
EP0440426A1 (fr) * 1990-01-30 1991-08-07 Bard Connaught Manchette hémostatique pouvant être utilisée avec un cathéter
WO1992007507A1 (fr) * 1990-10-29 1992-05-14 Boston Scientific Corporation Fil transformable en fil de guidage-catheter a extremite souple

Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5947940A (en) * 1997-06-23 1999-09-07 Beisel; Robert F. Catheter reinforced to prevent luminal collapse and tensile failure thereof
US8328771B2 (en) 1999-07-19 2012-12-11 Roger Dillard Massengale Method for fluid delivery and catheters for use with same
US9084870B2 (en) 1999-07-19 2015-07-21 Avent, Inc. Catheter for uniform delivery of medication
US8628633B2 (en) 1999-07-19 2014-01-14 Kimberly-Clark Worldwide, Inc. Catheter for uniform delivery of medication
US7569045B2 (en) 1999-07-19 2009-08-04 I-Flow Corporation Catheter for uniform delivery of medication
US8043465B2 (en) 1999-07-19 2011-10-25 I-Flow Corporation Catheter for uniform delivery of medication
US7438711B2 (en) 1999-07-19 2008-10-21 I-Flow Corporation Catheter for uniform delivery of medication
US7959623B2 (en) 1999-07-19 2011-06-14 I-Flow Corporation Method of fluid delivery and catheters for use with same
US7547302B2 (en) 1999-07-19 2009-06-16 I-Flow Corporation Anti-microbial catheter
US8343135B2 (en) 1999-07-19 2013-01-01 Kimberly-Clark Worldwide, Inc. Anti-microbial catheter
US7780638B1 (en) 1999-07-19 2010-08-24 I-Flow Corporation Catheter for uniform delivery of medication
WO2001070322A1 (fr) * 2000-03-24 2001-09-27 Stephen Brushey Catheter pour anesthesie
US7462177B2 (en) 2000-03-24 2008-12-09 Micor, Inc. Anesthesia conduction catheter
US6676643B2 (en) 2000-03-24 2004-01-13 Nicor, Inc. Anesthesia conduction catheter
US6689110B2 (en) 2000-03-24 2004-02-10 Micor, Inc. Anesthesia conduction catheter
US8105311B2 (en) 2002-12-11 2012-01-31 Abbott Laboratories Vascular Enterprises Limited Catheter with bendable section
EP1656964A1 (fr) * 2002-12-11 2006-05-17 Abbott Laboratories Vascular Enterprises Limited Cathéter
EP1428545A1 (fr) * 2002-12-11 2004-06-16 Abbott Laboratories Vascular Enterprises Limited Cathéter
US8827950B2 (en) 2002-12-11 2014-09-09 Abbott Laboratories Vascular Enterprises Limited Catheter
US8353876B2 (en) 2008-01-30 2013-01-15 Becton, Dickinson And Company Occlusion resistant catheters
WO2009097289A1 (fr) * 2008-01-30 2009-08-06 Becton, Dickinson And Company Cathéters résistant à l'occlusion
US20090227987A1 (en) * 2008-03-07 2009-09-10 Howard Singer Device for treating pneumothorax, tension pneumothorax, pleural effusion, and hemothorax in neonates
US9033955B2 (en) * 2008-03-07 2015-05-19 Howard Singer Device for treating pneumothorax, tension pneumothorax, pleural effusion, and hemothorax in neonates
EP2679268A1 (fr) * 2012-06-27 2014-01-01 Peak Medical Ltd. Système de cathéter de perfusion
US11357962B2 (en) 2013-02-13 2022-06-14 Becton, Dickinson And Company Blood control IV catheter with stationary septum activator
US10589063B2 (en) 2014-04-23 2020-03-17 Becton, Dickinson And Company Antimicrobial obturator for use with vascular access devices
US10376686B2 (en) 2014-04-23 2019-08-13 Becton, Dickinson And Company Antimicrobial caps for medical connectors
US9956379B2 (en) 2014-04-23 2018-05-01 Becton, Dickinson And Company Catheter tubing with extraluminal antimicrobial coating
US11357965B2 (en) 2014-04-23 2022-06-14 Becton, Dickinson And Company Antimicrobial caps for medical connectors
US9789279B2 (en) 2014-04-23 2017-10-17 Becton, Dickinson And Company Antimicrobial obturator for use with vascular access devices
US10232088B2 (en) 2014-07-08 2019-03-19 Becton, Dickinson And Company Antimicrobial coating forming kink resistant feature on a vascular access device
US10493244B2 (en) 2015-10-28 2019-12-03 Becton, Dickinson And Company Extension tubing strain relief
US11904114B2 (en) 2015-10-28 2024-02-20 Becton, Dickinson And Company Extension tubing strain relief

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