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WO1996019205B1 - Systeme de liberation transdermique avec opercule adhesif et rondelle pelable - Google Patents

Systeme de liberation transdermique avec opercule adhesif et rondelle pelable

Info

Publication number
WO1996019205B1
WO1996019205B1 PCT/US1995/016498 US9516498W WO9619205B1 WO 1996019205 B1 WO1996019205 B1 WO 1996019205B1 US 9516498 W US9516498 W US 9516498W WO 9619205 B1 WO9619205 B1 WO 9619205B1
Authority
WO
WIPO (PCT)
Prior art keywords
peel seal
backing layer
active agent
seal disc
adhesive
Prior art date
Application number
PCT/US1995/016498
Other languages
English (en)
Other versions
WO1996019205A1 (fr
Filing date
Publication date
Application filed filed Critical
Priority to EP95943869A priority Critical patent/EP0799029A1/fr
Priority to AU45233/96A priority patent/AU695170B2/en
Priority to JP8519931A priority patent/JPH10511353A/ja
Publication of WO1996019205A1 publication Critical patent/WO1996019205A1/fr
Publication of WO1996019205B1 publication Critical patent/WO1996019205B1/fr
Priority to MXPA/A/1997/004291A priority patent/MXPA97004291A/xx

Links

Abstract

Dispositif (10) conçu pour appliquer une substance active sur la peau ou les muqueuses d'un individu, qui est constitué des parties suivantes: un composite laminaire d'un opercule adhésif (26), une couche dorsale (14) sur laquelle repose la partie centrale de l'opercule, une membrane active (16) perméable à la substance administrée, la couche dorsale et la membrane qui délimitent un réceptacle (12) contenant la formulation de la substance active, une rondelle pelable (20) sur laquelle repose la membrane active perméable à la substance, un joint à thermoscellage (22) sur le pourtour de la rondelle pelable. La membrane active perméable à la substance, la couche dorsale et un revêtement intérieur amovible (24) de diffusion sont à la base de la partie exposée de l'opercule et de la rondelle pelable. Le revêtement adhésif est placé au-dessus et en bordure de la trajectoire de la substance active vers la peau et les muqueuses et il est protégé de la dégradation des composants du réceptacle par plusieurs joints à thermoscellage. La rondelle pelable sert de protection contre la diffusion de la substance active contenue dans le réceptacle et le revêtement intérieur de diffusion empêche la partie adhésive d'être exposée à l'environnement extérieur avant toute utilisation.
PCT/US1995/016498 1994-12-21 1995-12-08 Systeme de liberation transdermique avec opercule adhesif et rondelle pelable WO1996019205A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP95943869A EP0799029A1 (fr) 1994-12-21 1995-12-08 Systeme de liberation transdermique avec opercule adhesif et rondelle pelable
AU45233/96A AU695170B2 (en) 1994-12-21 1995-12-08 Transdermal delivery system with adhesive overlay and peel seal disc
JP8519931A JPH10511353A (ja) 1994-12-21 1995-12-08 接着剤オーバーレイおよび剥離性シールディスクを用いた経皮送達システム
MXPA/A/1997/004291A MXPA97004291A (en) 1994-12-21 1997-06-10 System of release transdermica conrecubrimiento adhesivo and disco de selladodesprendi

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36180094A 1994-12-21 1994-12-21
US08/361,800 1994-12-21

Publications (2)

Publication Number Publication Date
WO1996019205A1 WO1996019205A1 (fr) 1996-06-27
WO1996019205B1 true WO1996019205B1 (fr) 1996-08-08

Family

ID=23423499

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/016498 WO1996019205A1 (fr) 1994-12-21 1995-12-08 Systeme de liberation transdermique avec opercule adhesif et rondelle pelable

Country Status (9)

Country Link
US (1) US5662925A (fr)
EP (1) EP0799029A1 (fr)
JP (1) JPH10511353A (fr)
CN (1) CN1170360A (fr)
AU (1) AU695170B2 (fr)
CA (1) CA2208132A1 (fr)
TW (1) TW438607B (fr)
WO (1) WO1996019205A1 (fr)
ZA (1) ZA9510786B (fr)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962011A (en) * 1993-12-06 1999-10-05 Schering-Plough Healthcare Products, Inc. Device for delivery of dermatological ingredients
CA2259370C (fr) 1996-07-02 2007-10-23 Minnesota Mining And Manufacturing Company Element composite adhesif a usage medical et conditionnement
WO1998000118A2 (fr) * 1996-07-03 1998-01-08 Alza Corporation Dispositifs d'administration de medicaments et procede de fabrication
US6007837A (en) * 1996-07-03 1999-12-28 Alza Corporation Drug delivery devices and process of manufacture
US5738647A (en) * 1996-09-27 1998-04-14 Becton Dickinson And Company User activated iontophoretic device and method for activating same
US5797867A (en) * 1996-09-27 1998-08-25 Becton Dickinson And Company Iontophoretic drug delivery system, including method for activating same for attachment to patient
US6174545B1 (en) 1997-07-01 2001-01-16 Alza Corporation Drug delivery devices and process of manufacture
US6086912A (en) * 1998-02-11 2000-07-11 Gilman; Marvin S. Topical drug delivery system
US6120792A (en) * 1998-04-29 2000-09-19 Juni; Jack E. Medicated skin patch and method for its use
US6761896B1 (en) * 1998-10-29 2004-07-13 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Skin cosmetic care system and method
US6475514B1 (en) 1998-12-03 2002-11-05 Andrew Blitzer Athletic patch
US6284941B1 (en) 1999-03-09 2001-09-04 Craig M. Cox Bandage having a scar treatment pad for scar management and scar repair
WO2000054755A1 (fr) * 1999-03-17 2000-09-21 Barbara Sheila Goldberg Distributeur adhesif
US20030102246A1 (en) * 1999-03-20 2003-06-05 Lts Lohmann Therapie-Systeme Ag Method for improving the stability of stored and/or used light-sensitive therapeutic systems or components thereof
MXPA02000053A (es) 1999-07-05 2003-07-21 Idea Ag Un metodo para mejorar el tratamiento a traves de barreras adaptables semipermeables.
DE19943317C1 (de) * 1999-09-10 2001-03-15 Lohmann Therapie Syst Lts Kunststofffolien, insbesondere für die Verwendung in einem dermalen oder transdermalen therapeutischen System und Verfahren zu ihrer Herstellung
US6344021B1 (en) * 2000-03-03 2002-02-05 Robert W. Juster Magnetic therapy patch
JP2003534368A (ja) * 2000-06-01 2003-11-18 ワトソン ファーマシューティカルズ， インコーポレイテッド ラゾフォキシフェンの経皮送達
JP4627582B2 (ja) * 2000-06-23 2011-02-09 ニプロパッチ株式会社 経皮吸収又は経粘膜吸収用の投与デバイス
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
US20040092494A9 (en) * 2000-08-30 2004-05-13 Dudley Robert E. Method of increasing testosterone and related steroid concentrations in women
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
ATE502657T1 (de) 2001-05-01 2011-04-15 Av Topchiev Inst Petrochemical Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
EP1390085B1 (fr) 2001-05-01 2009-08-05 A.V. Topchiev Institute of Petrochemical Synthesis Compositions d'hydrogel
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US6506403B1 (en) * 2001-08-21 2003-01-14 Qi Yu Treatment patch
US6676961B1 (en) 2002-03-06 2004-01-13 Automated Carrier Technologies, Inc. Transdermal patch assembly
US20040105881A1 (en) 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
CA2453013C (fr) 2002-12-13 2011-02-15 Gary W. Cleary Dispositifs d'administration d'ingredients par voie percutanee, transdermique ou transmuqueuse ou par les muqueuses
US20040214215A1 (en) * 2003-03-07 2004-10-28 Yu Ruey J. Bioavailability and improved delivery of alkaline pharmaceutical drugs
US20040220264A1 (en) * 2003-03-17 2004-11-04 Yu Ruey J Bioavailability and improved delivery of acidic pharmaceutical drugs
US7888546B2 (en) 2003-07-03 2011-02-15 Corium International, Inc. Wound dressing, ingredient delivery device and IV hold-down, and method relating to same
US8524272B2 (en) 2003-08-15 2013-09-03 Mylan Technologies, Inc. Transdermal patch incorporating active agent migration barrier layer
AU2005210637B2 (en) 2004-01-30 2010-09-16 A.V. Topchiev Institute Of Petrochemical Synthesis Rapidly dissolving film for delivery of an active agent
US20050196418A1 (en) * 2004-03-04 2005-09-08 Yu Ruey J. Bioavailability and improved delivery of alkaline pharmaceutical drugs
JP5270158B2 (ja) 2004-08-05 2013-08-21 コリウム インターナショナル， インコーポレイテッド 粘着性組成物
JP4933435B2 (ja) 2004-09-14 2012-05-16 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・コロラド，ア・ボディー・コーポレイト 遺伝子ターゲティングに基づくブシンドロール処置方法
US7771342B2 (en) * 2004-09-29 2010-08-10 Patrick J. Rademacher Apparatus and method for reducing vision problems as a result of floaters
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
DK2450041T3 (en) 2005-10-12 2018-11-19 Unimed Pharmaceuticals Llc Enhanced testosterone gel for use in the treatment of hypogonadism
WO2007065428A1 (fr) * 2005-12-08 2007-06-14 Fertin Pharma Timbre transdermique d'alcaloide du tabac a faible resistance a la flexion
CA2667678A1 (fr) 2006-10-25 2008-07-24 Amgen Inc. Agents therapeutiques a base de peptides toxiques
DE102007006244B4 (de) * 2007-02-08 2012-03-15 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System zur Verabreichung wasserlöslicher Wirkstoffe
US8420779B2 (en) * 2007-05-22 2013-04-16 Amgen Inc. Compositions and methods for producing bioactive fusion proteins
JP5603235B2 (ja) * 2007-07-10 2014-10-08 アージャイル セラピューティクス， インコーポレイテッド イン・サイチュシールを有する経皮送達デバイス
US20100178323A1 (en) * 2007-07-10 2010-07-15 Agis Kydonieus Dermal Delivery Device
US20100292660A1 (en) * 2007-07-10 2010-11-18 Agis Kydonieus Dermal delivery device with ultrasonic weld
US20100028413A1 (en) * 2008-08-04 2010-02-04 Aida Picone Skin treatment strip
EP2201941A1 (fr) * 2008-12-29 2010-06-30 UCB Pharma GmbH Technologie de fabrication de pavé
AU2010204986B2 (en) 2009-01-14 2016-06-02 Corium International, Inc. Transdermal administration of tamsulosin
US8920392B2 (en) 2009-05-05 2014-12-30 Watson Laboratories, Inc. Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions
US9512481B2 (en) 2009-09-11 2016-12-06 The Regents Of The University Of Colorado, A Body Corporate Polymorphisms in the PDE3A gene
EP2482774B1 (fr) * 2009-09-30 2018-01-31 Mölnlycke Health Care AB Procédé de fixation de languettes de saisie d'une couche de support de pansement film
ES2587191T3 (es) 2009-12-23 2016-10-21 Arca Biopharma, Inc. Métodos y composiciones para enfermedades y afecciones cardiovasculares
EA026254B1 (ru) 2010-11-23 2017-03-31 Тева Фармасьютикалс Интернешнл Гмбх Активируемая пользователем автономная выполненная в едином корпусе система доставки лекарственного средства посредством ионофореза
PE20140593A1 (es) 2011-03-16 2014-05-10 Amgen Inc Inhibidores potentes y selectivos de nav1.3 y nav1.7
WO2013049507A1 (fr) 2011-09-30 2013-04-04 Perio Sciences, Llc Compositions antioxydantes pour le traitement de l'inflammation ou de dommages oxydatifs
EP2970408B1 (fr) 2013-03-12 2018-01-10 Amgen Inc. Inhibiteurs sélectifs et puissants de nav1.7
WO2015089310A1 (fr) * 2013-12-11 2015-06-18 Atkinson Oscar Revêtement cutané occlusif
US11607026B2 (en) * 2014-05-30 2023-03-21 Johnson & Johnson Consumer Inc. Device for delivery of skin care composition
WO2016107897A1 (fr) * 2014-12-30 2016-07-07 Mactac Europe Sprl Bande adhésive multicouche pour comprimer et contracter une cicatrice
EP3067050A1 (fr) 2015-03-13 2016-09-14 Acino AG Système thérapeutique transdermique avec bande de recouvrement comprenant deux couches adhésives
JP6484502B2 (ja) * 2015-06-09 2019-03-13 新光電気工業株式会社 絆創膏型モジュール
KR101636069B1 (ko) * 2015-12-08 2016-07-11 주식회사 라파스 마이크로구조체 제조방법
JP6833855B2 (ja) 2015-12-30 2021-02-24 コリウム， インコーポレイテッド 長期間経皮投与のためのシステムおよび方法
WO2017223402A1 (fr) 2016-06-23 2017-12-28 Corium International, Inc. Matrice adhésive à un domaine hydrophile, un domaine hydrophobes et un agent thérapeutique
AU2017301928B2 (en) 2016-07-27 2023-04-06 Corium, LLC. Donepezil transdermal delivery system
WO2018022818A1 (fr) 2016-07-27 2018-02-01 Corium International, Inc. Systèmes d'administration transdermique de mémantine
US11318190B2 (en) 2017-05-05 2022-05-03 United States Government As Represented By The Department Of Veterans Affairs Methods and compositions for treating liver disease
GB2561262B (en) * 2017-07-13 2019-03-20 Dentmed Ltd A targeted drug delivery pad
CA3071007A1 (fr) * 2017-07-26 2019-01-31 Corium, Inc. Systeme d'administration transdermique avec une membrane microporeuse ayant des pores remplis de solvant
CA3086163A1 (fr) 2017-12-20 2019-06-27 Corium, Inc. Composition adhesive transdermique comprenant un agent therapeutique liquide volatil a bas point de fusion
US11185287B2 (en) * 2018-06-22 2021-11-30 Vital Connect, Inc. Adhesive overlay

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US4405616A (en) * 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US4316893A (en) * 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
US3989816A (en) * 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
US4060084A (en) * 1976-09-07 1977-11-29 Alza Corporation Method and therapeutic system for providing chemotherapy transdermally
ATE12731T1 (de) * 1979-01-11 1985-05-15 Key Pharma Polymere diffusionsmatrix und verfahren zu deren herstellung.
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
US4650484A (en) * 1983-02-03 1987-03-17 Alza Corporation Method for treating ischemic conditions
ES8608895A1 (es) * 1984-08-17 1986-07-16 Allpack Ind Lohnverpackung Parche adhesivo farmaceutico y procedimiento para su fabri- cacion
US4710191A (en) * 1985-12-16 1987-12-01 Jonergin, Inc. Therapeutic device for the administration of medicaments
US4863970A (en) * 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
US4983395A (en) * 1987-11-12 1991-01-08 Theratech Inc. Device for administering an active agent to the skin or mucosa
US4849224A (en) * 1987-11-12 1989-07-18 Theratech Inc. Device for administering an active agent to the skin or mucosa
US5202125A (en) * 1990-12-10 1993-04-13 Theratech, Inc. Method and systems for administering nitroglycerin transdermally at enhanced transdermal fluxes
WO1993023019A1 (fr) * 1992-05-11 1993-11-25 Sri International Dispositifs d'apport medicamenteux transcutane, compositions qui y sont associees et procedes d'utilisation

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