WO1996020595B1 - Modulation du niveau des metabolites toxiques dans les produits de consommation - Google Patents
Modulation du niveau des metabolites toxiques dans les produits de consommationInfo
- Publication number
- WO1996020595B1 WO1996020595B1 PCT/US1995/017049 US9517049W WO9620595B1 WO 1996020595 B1 WO1996020595 B1 WO 1996020595B1 US 9517049 W US9517049 W US 9517049W WO 9620595 B1 WO9620595 B1 WO 9620595B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- carbon atoms
- organic substituent
- mycotoxin
- producing
- cho
- Prior art date
Links
- 239000002207 metabolite Substances 0.000 title 1
- 231100000331 toxic Toxicity 0.000 title 1
- 230000002588 toxic effect Effects 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 16
- 125000001424 substituent group Chemical group 0.000 claims abstract 16
- 238000000034 method Methods 0.000 claims abstract 12
- 239000000203 mixture Substances 0.000 claims abstract 12
- 231100000678 Mycotoxin Toxicity 0.000 claims abstract 11
- 239000002636 mycotoxin Substances 0.000 claims abstract 11
- 241000233866 Fungi Species 0.000 claims abstract 8
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims abstract 4
- 244000005700 microbiome Species 0.000 claims abstract 4
- 150000001875 compounds Chemical class 0.000 claims 6
- 230000009885 systemic effect Effects 0.000 claims 3
- KJPRLNWUNMBNBZ-QPJJXVBHSA-N (E)-cinnamaldehyde Chemical compound O=C\C=C\C1=CC=CC=C1 KJPRLNWUNMBNBZ-QPJJXVBHSA-N 0.000 claims 2
- 208000035240 Disease Resistance Diseases 0.000 claims 2
- AXMVYSVVTMKQSL-UHFFFAOYSA-N UNPD142122 Natural products OC1=CC=C(C=CC=O)C=C1O AXMVYSVVTMKQSL-UHFFFAOYSA-N 0.000 claims 2
- 229940117916 cinnamic aldehyde Drugs 0.000 claims 2
- KJPRLNWUNMBNBZ-UHFFFAOYSA-N cinnamic aldehyde Natural products O=CC=CC1=CC=CC=C1 KJPRLNWUNMBNBZ-UHFFFAOYSA-N 0.000 claims 2
- DKZBBWMURDFHNE-NSCUHMNNSA-N coniferyl aldehyde Chemical compound COC1=CC(\C=C\C=O)=CC=C1O DKZBBWMURDFHNE-NSCUHMNNSA-N 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- 230000001988 toxicity Effects 0.000 claims 2
- 231100000419 toxicity Toxicity 0.000 claims 2
- DKZBBWMURDFHNE-UHFFFAOYSA-N trans-coniferylaldehyde Natural products COC1=CC(C=CC=O)=CC=C1O DKZBBWMURDFHNE-UHFFFAOYSA-N 0.000 claims 2
- -1 R2 represents -H Chemical group 0.000 claims 1
- GUUHFMWKWLOQMM-NTCAYCPXSA-N alpha-hexylcinnamaldehyde Chemical compound CCCCCC\C(C=O)=C/C1=CC=CC=C1 GUUHFMWKWLOQMM-NTCAYCPXSA-N 0.000 claims 1
- GUUHFMWKWLOQMM-UHFFFAOYSA-N alpha-n-hexylcinnamic aldehyde Natural products CCCCCCC(C=O)=CC1=CC=CC=C1 GUUHFMWKWLOQMM-UHFFFAOYSA-N 0.000 claims 1
- 230000000443 biocontrol Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 230000017066 negative regulation of growth Effects 0.000 claims 1
- 238000012794 pre-harvesting Methods 0.000 claims 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 claims 1
- 229930182490 saponin Natural products 0.000 claims 1
- 150000007949 saponins Chemical group 0.000 claims 1
- 235000013311 vegetables Nutrition 0.000 abstract 3
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 2
- 239000003053 toxin Substances 0.000 abstract 2
- 241000196324 Embryophyta Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 abstract 1
- 244000061176 Nicotiana tabacum Species 0.000 abstract 1
- 240000008042 Zea mays Species 0.000 abstract 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 239000004464 cereal grain Substances 0.000 abstract 1
- 235000020971 citrus fruits Nutrition 0.000 abstract 1
- 235000005822 corn Nutrition 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 235000011868 grain product Nutrition 0.000 abstract 1
- 238000003306 harvesting Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 238000012956 testing procedure Methods 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
Abstract
L'invention concerne des méthodes et des compositions qui permettent de contrôler le niveau des métabolites toxiques dans les produits d'origine végétale, pendant et/ou après la récolte et/ou le traitement. Ces moyens permettent de réduire les risques sanitaires liés à l'utilisation de produits de consommation tels que le tabac, les céréales utilisées pour l'alimentation, les produits traités à base de céréales comme le sirop de maïs, ou bien encore les agrumes, les tubercules, les fruits et légumes, les fleurs, les légumes à feuilles et à tiges ou les fleurs coupées, et aussi d'améliorer les procédures de contrôle des animaux en laboratoire, en vérifiant le niveau des mycotoxines associées aux substances qui s'établissent dans les microorganismes producteurs de toxines. Les compositions qui permettent de contrôler les micromycètes producteurs de mycotoxines comprennent l'aldéhyde cinnamique, l'aldéhyde conférylique ou leurs dérivés, selon la formule (I). Dans ladite formule, R1 est -CHO, R2 est -OH ou un substituant organique comportant de 1 à 10 atomes de carbone, R3 est -OCH3 ou un substituant organique comportant de 1 à 10 atomes de carbone, et R4 est -H ou un substituant organique comportant de 1 à 10 atomes de carbone.
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU47442/96A AU4744296A (en) | 1994-12-30 | 1995-12-29 | Modulating toxic metabolite levels in consumable products |
| EP95944684A EP0800345B1 (fr) | 1994-12-30 | 1995-12-29 | Modulation du niveau des metabolites toxiques dans les produits de consommation |
| JP8521176A JPH11501295A (ja) | 1994-12-30 | 1995-12-29 | 消耗製品における有毒代謝産物レベルの調節 |
| AT95944684T ATE215307T1 (de) | 1994-12-30 | 1995-12-29 | Regulierung des gehaltes toxischer metaboliten in nahrungsmitteln |
| NZ301911A NZ301911A (en) | 1994-12-30 | 1995-12-29 | Biocontrol of mycotoxin-producing micro-organisms |
| BR9510180A BR9510180A (pt) | 1994-12-30 | 1995-12-29 | Processo para controlar o crescimento de fungos produzido micotoxinas em uma parte de planta composição uso da mesma plantas ou partes de plantas substancialmente isentas de fungos prouzindo microtoxina e processo para induzir resintênica a fungos produzindo uma miciotoxina |
| DE69526251T DE69526251T2 (de) | 1994-12-30 | 1995-12-29 | Regulierung des gehaltes toxischer metaboliten in nahrungsmitteln |
| MXPA/A/1997/004964A MXPA97004964A (en) | 1994-12-30 | 1997-06-30 | Modulation of the levels of toxic metabolites in consumib products |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36708294A | 1994-12-30 | 1994-12-30 | |
| US08/367,082 | 1994-12-30 | ||
| US48503595A | 1995-06-07 | 1995-06-07 | |
| US08/485,035 | 1995-06-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1996020595A1 WO1996020595A1 (fr) | 1996-07-11 |
| WO1996020595B1 true WO1996020595B1 (fr) | 1996-09-26 |
Family
ID=33302708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US1995/017049 WO1996020595A1 (fr) | 1994-12-30 | 1995-12-29 | Modulation du niveau des metabolites toxiques dans les produits de consommation |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0800345B1 (fr) |
| JP (1) | JPH11501295A (fr) |
| AT (1) | ATE215307T1 (fr) |
| AU (1) | AU4744296A (fr) |
| BR (1) | BR9510180A (fr) |
| CA (1) | CA2208753A1 (fr) |
| DE (1) | DE69526251T2 (fr) |
| NZ (1) | NZ301911A (fr) |
| PL (1) | PL321179A1 (fr) |
| WO (1) | WO1996020595A1 (fr) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6410718B1 (en) | 1996-09-11 | 2002-06-25 | Genesis Research & Development Corporation Ltd. | Materials and methods for the modification of plant lignin content |
| US5850020A (en) * | 1996-09-11 | 1998-12-15 | Genesis Research & Development Corporation, Ltd. | Materials and method for the modification of plant lignin content |
| US7087426B2 (en) | 1996-09-11 | 2006-08-08 | Agrigenesis Biosciences Ltd. | Materials and methods for the modification of plant lignin content |
| US6204434B1 (en) | 1996-09-11 | 2001-03-20 | Genesis Research & Development Corporation Limited | Materials and methods for the modification of plant lignin content |
| US5846812A (en) * | 1996-11-22 | 1998-12-08 | Pioneer Hi-Bred International, Inc. | Zearalenone detoxification compositions and methods |
| US5798255A (en) * | 1996-11-22 | 1998-08-25 | Pioneer Hi-Bred International, Inc. | Beauvericin detoxification compositions and methods |
| PT932663E (pt) * | 1996-11-22 | 2000-12-29 | Pioneer Hi Bred Int | Composicoes e metodos para eliminar a toxicidade da moniliformina |
| AU7983498A (en) * | 1997-06-20 | 1999-01-04 | Applied Phytologics, Inc. | Pathogen-resistant monocot plants and method |
| US6060646A (en) * | 1997-08-12 | 2000-05-09 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture | Tolerance of trichothecene mycotoxins in plants and animals through the modification of the peptidyl transferase gene |
| US6855872B2 (en) | 1997-08-12 | 2005-02-15 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food | Tolerance of trichothecene mycotoxins in plants through the modification of the ribosomal protein L3 gene |
| AU8919098A (en) * | 1997-08-26 | 1999-03-16 | North Carolina State University | Fumonosin resistance |
| US6538177B1 (en) | 1998-07-15 | 2003-03-25 | Pioneer Hi-Bred International, Inc. | Compositions and methods for fumonisin detoxification |
| BR9912076A (pt) | 1998-07-15 | 2002-02-05 | Pionner Hi Bred International | Polinucleotìdeos de amino poliol amina oxidase e polipeptìdeos relacionados e métodos de uso |
| US6943279B1 (en) | 1999-07-12 | 2005-09-13 | Pioneer Hi-Bred International, Inc. | Amino polyol amine oxidase polynucleotides and related polypeptides and methods of use |
| WO2000004160A1 (fr) * | 1998-07-15 | 2000-01-27 | Pioneer Hi-Bred International, Inc. | Polynucleotides d'aminopolyolamineoxydase, polypeptides associes, et leur modes d'utilisation |
| NZ544044A (en) | 1998-10-09 | 2007-12-21 | Genesis Res & Dev Corp Ltd | Materials and methods for the modification of plant lignin content |
| US7129393B1 (en) | 1999-02-22 | 2006-10-31 | Yissum Research Development Company Of The Hebrew University | Transgenic plants and method for transforming carnations |
| AU2687000A (en) * | 1999-02-22 | 2000-09-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Transgenic plants and method for transforming carnations |
| US6074838A (en) * | 1999-05-20 | 2000-06-13 | Pioneer Hi-Bred International, Inc. | Zearalenone detoxification compositions and methods |
| US6388171B1 (en) | 1999-07-12 | 2002-05-14 | Pioneer Hi-Bred International, Inc. | Compositions and methods for fumonisin detoxification |
| EP1196601A1 (fr) * | 1999-07-14 | 2002-04-17 | Pioneer Hi-Bred International Inc. | Compositions et procedes de detoxication de fumonisine |
| JP2003516723A (ja) * | 1999-10-18 | 2003-05-20 | ケリー・スコット・レーン | タバコ製品を加工する間に有害トキシンをアッセイ及び除去する方法及びシステム |
| ES2163999B1 (es) * | 1999-11-11 | 2003-03-01 | Inabonos Sa | Composicion de origen natural para controlar la patologia post-cosecha de frutas y hortalizas y metodo de aplicacion. |
| US6812380B2 (en) | 2001-03-27 | 2004-11-02 | Pioneer Hi-Bred International, Inc. | Compositions and methods of zearalenone detoxification |
| CA2596049A1 (fr) | 2005-01-26 | 2006-08-03 | Emma Kvitnitsky | Compositions et methodes de protection de fruits recoltes contre la pourriture |
| US9988352B2 (en) | 2014-06-06 | 2018-06-05 | Board Of Trustees Of Michigan State University | Compounds for inhibition of fungal toxin production |
| KR101797713B1 (ko) * | 2015-05-14 | 2017-11-16 | 한국과학기술원 | 신남알데하이드의 제조 방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR8206283A (pt) * | 1982-07-06 | 1984-04-17 | Kiyoshi Saotome | Processo para protecao de culturas |
| JPS6165802A (ja) * | 1984-09-10 | 1986-04-04 | Maruzen Kasei Kk | 保存料 |
| JP2621114B2 (ja) * | 1987-04-13 | 1997-06-18 | 清 五月女 | 無毒の組成物による農作物の保護方法 |
| US5149715A (en) * | 1989-02-09 | 1992-09-22 | Monterey Mushroom, Inc. | Control of fungal diseases in the production of mushrooms |
| JPH05139924A (ja) * | 1991-11-25 | 1993-06-08 | Itouen:Kk | 天然成分を有効成分とする植物病害防除剤 |
-
1995
- 1995-12-29 NZ NZ301911A patent/NZ301911A/xx not_active IP Right Cessation
- 1995-12-29 JP JP8521176A patent/JPH11501295A/ja active Pending
- 1995-12-29 AT AT95944684T patent/ATE215307T1/de not_active IP Right Cessation
- 1995-12-29 DE DE69526251T patent/DE69526251T2/de not_active Expired - Lifetime
- 1995-12-29 PL PL95321179A patent/PL321179A1/xx unknown
- 1995-12-29 AU AU47442/96A patent/AU4744296A/en not_active Abandoned
- 1995-12-29 BR BR9510180A patent/BR9510180A/pt not_active Application Discontinuation
- 1995-12-29 WO PCT/US1995/017049 patent/WO1996020595A1/fr active IP Right Grant
- 1995-12-29 CA CA002208753A patent/CA2208753A1/fr not_active Abandoned
- 1995-12-29 EP EP95944684A patent/EP0800345B1/fr not_active Expired - Lifetime
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