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WO1997000671A3 - Composition for preparing finely dispersed systems and process for preparing the same - Google Patents

Composition for preparing finely dispersed systems and process for preparing the same Download PDF

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Publication number
WO1997000671A3
WO1997000671A3 PCT/EP1996/002709 EP9602709W WO9700671A3 WO 1997000671 A3 WO1997000671 A3 WO 1997000671A3 EP 9602709 W EP9602709 W EP 9602709W WO 9700671 A3 WO9700671 A3 WO 9700671A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparing
finely dispersed
composition
dispersed systems
same
Prior art date
Application number
PCT/EP1996/002709
Other languages
German (de)
French (fr)
Other versions
WO1997000671A2 (en
Inventor
Guenther Maierhofer
Ensenat Pedro Gonzales
Original Assignee
Dianorm G Maierhofer Gmbh
Guenther Maierhofer
Ensenat Pedro Gonzales
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dianorm G Maierhofer Gmbh, Guenther Maierhofer, Ensenat Pedro Gonzales filed Critical Dianorm G Maierhofer Gmbh
Publication of WO1997000671A2 publication Critical patent/WO1997000671A2/en
Publication of WO1997000671A3 publication Critical patent/WO1997000671A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K23/00Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
    • C09K23/14Derivatives of phosphoric acid
    • DTEXTILES; PAPER
    • D06TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06MTREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
    • D06M13/00Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment
    • D06M13/10Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with compounds containing oxygen
    • D06M13/144Alcohols; Metal alcoholates
    • DTEXTILES; PAPER
    • D06TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06MTREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
    • D06M13/00Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment
    • D06M13/10Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with compounds containing oxygen
    • D06M13/184Carboxylic acids; Anhydrides, halides or salts thereof
    • D06M13/207Substituted carboxylic acids, e.g. by hydroxy or keto groups; Anhydrides, halides or salts thereof
    • DTEXTILES; PAPER
    • D06TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06MTREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
    • D06M13/00Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment
    • D06M13/322Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with compounds containing nitrogen
    • D06M13/44Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with compounds containing nitrogen containing nitrogen and phosphorus
    • D06M13/453Phosphates or phosphites containing nitrogen atoms
    • DTEXTILES; PAPER
    • D06TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06PDYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
    • D06P1/00General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed
    • D06P1/44General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed using insoluble pigments or auxiliary substances, e.g. binders
    • D06P1/64General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed using insoluble pigments or auxiliary substances, e.g. binders using compositions containing low-molecular-weight organic compounds without sulfate or sulfonate groups
    • D06P1/651Compounds without nitrogen
    • D06P1/65106Oxygen-containing compounds
    • D06P1/65118Compounds containing hydroxyl groups
    • DTEXTILES; PAPER
    • D06TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06PDYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
    • D06P1/00General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed
    • D06P1/44General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed using insoluble pigments or auxiliary substances, e.g. binders
    • D06P1/653Nitrogen-free carboxylic acids or their salts
    • DTEXTILES; PAPER
    • D06TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06PDYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
    • D06P1/00General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed
    • D06P1/44General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed using insoluble pigments or auxiliary substances, e.g. binders
    • D06P1/667Organo-phosphorus compounds
    • DTEXTILES; PAPER
    • D21PAPER-MAKING; PRODUCTION OF CELLULOSE
    • D21HPULP COMPOSITIONS; PREPARATION THEREOF NOT COVERED BY SUBCLASSES D21C OR D21D; IMPREGNATING OR COATING OF PAPER; TREATMENT OF FINISHED PAPER NOT COVERED BY CLASS B31 OR SUBCLASS D21G; PAPER NOT OTHERWISE PROVIDED FOR
    • D21H21/00Non-fibrous material added to the pulp, characterised by its function, form or properties; Paper-impregnating or coating material, characterised by its function, form or properties
    • D21H21/14Non-fibrous material added to the pulp, characterised by its function, form or properties; Paper-impregnating or coating material, characterised by its function, form or properties characterised by function or properties in or on the paper
    • D21H21/28Colorants ; Pigments or opacifying agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Textile Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

A composition contains at least one phospholipid, at least one bile acid and/or at least one bile acid derivative, ethanol and water. This composition is useful for preparing finely dispersed systems that remain stable even after a long storage time. The finely dispersed systems are particularly useful for preparing pharmaceutical or cosmetic compositions and have biological activity although they do not contain a usual pharmaceutical active substance.
PCT/EP1996/002709 1995-06-22 1996-06-21 Composition for preparing finely dispersed systems and process for preparing the same WO1997000671A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19522693.3 1995-06-22
DE19522693A DE19522693A1 (en) 1995-06-22 1995-06-22 Composition for the production of finely dispersed systems and process for their production

Publications (2)

Publication Number Publication Date
WO1997000671A2 WO1997000671A2 (en) 1997-01-09
WO1997000671A3 true WO1997000671A3 (en) 1997-02-13

Family

ID=7764997

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1996/002709 WO1997000671A2 (en) 1995-06-22 1996-06-21 Composition for preparing finely dispersed systems and process for preparing the same

Country Status (2)

Country Link
DE (1) DE19522693A1 (en)
WO (1) WO1997000671A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2111488B1 (en) * 1996-01-17 1998-11-01 Lucas Meyer S A USE OF PROLIPOSOMES COMPOSITIONS IN THE DYE, WHITENING AND SOFTENING OF THE TEXTILE INDUSTRY AND PROCEDURE FOR THE PREPARATION OF DYE BANKS FROM THESE PROLIPOSOME COMPOSITIONS.
DE19722831A1 (en) * 1997-05-30 1998-12-03 Univ Halle Wittenberg New vehicle system comprising stable, ternary mixed micelles
AU8285998A (en) * 1997-07-02 1999-01-25 Sdg, Inc. Targeted liposomal constructs for diagnostic and therapeutic uses
DE59914485D1 (en) * 1998-03-30 2007-10-18 Mibelle Ag Cosmetics Use of nanoemulsions to determine the biocompatibility of lipophilic substances in the cell culture test and suitable nanoemulsions
TWI241915B (en) 1998-05-11 2005-10-21 Ciba Sc Holding Ag A method of preparing a pharmaceutical end formulation using a nanodispersion
AU5916900A (en) * 1999-07-06 2001-01-22 Nutricology, Inc. Method for treatment of asthma syndrome
CZ300773B6 (en) * 2007-01-25 2009-08-05 Univerzita Pardubice Textile auxiliary agent liposome, process of its preparation and composition in which the liposome is comprised
CN105203576B (en) * 2015-09-17 2017-07-04 湖南师范大学 A kind of method for positioning spin probe active position in reversed micelle enzyme system

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115313A (en) * 1974-10-08 1978-09-19 Irving Lyon Bile acid emulsions
EP0133258A2 (en) * 1983-07-22 1985-02-20 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Injectable solutions for vitamin E
EP0252004A1 (en) * 1986-06-26 1988-01-07 Ciba-Geigy Ag Pharmaceutical compositions for parenteral application
EP0280887A1 (en) * 1987-02-03 1988-09-07 F. Hoffmann-La Roche Ag Mixed micelle solutions containing non-steroidal anti-inflammatory agents
EP0439042A1 (en) * 1990-01-24 1991-07-31 F. Hoffmann-La Roche AG Use of pharmaceutical and cosmetic preparations with mixed micellen
WO1994001089A1 (en) * 1992-07-08 1994-01-20 Dianorm-Geräte G. Maierhofer Liposomes, method of preparing them and their use in the preparation of drugs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4306475A1 (en) * 1993-03-02 1994-09-08 Ensenat Pedro Gonzalez Liposomes containing chlorhexidine diacetate or chlorhexidine digluconate

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115313A (en) * 1974-10-08 1978-09-19 Irving Lyon Bile acid emulsions
EP0133258A2 (en) * 1983-07-22 1985-02-20 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Injectable solutions for vitamin E
EP0252004A1 (en) * 1986-06-26 1988-01-07 Ciba-Geigy Ag Pharmaceutical compositions for parenteral application
EP0280887A1 (en) * 1987-02-03 1988-09-07 F. Hoffmann-La Roche Ag Mixed micelle solutions containing non-steroidal anti-inflammatory agents
EP0439042A1 (en) * 1990-01-24 1991-07-31 F. Hoffmann-La Roche AG Use of pharmaceutical and cosmetic preparations with mixed micellen
WO1994001089A1 (en) * 1992-07-08 1994-01-20 Dianorm-Geräte G. Maierhofer Liposomes, method of preparing them and their use in the preparation of drugs

Also Published As

Publication number Publication date
WO1997000671A2 (en) 1997-01-09
DE19522693A1 (en) 1997-01-02

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