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WO1997009039A3 - Composition comprising vitamin f - Google Patents

Composition comprising vitamin f Download PDF

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Publication number
WO1997009039A3
WO1997009039A3 PCT/US1996/015205 US9615205W WO9709039A3 WO 1997009039 A3 WO1997009039 A3 WO 1997009039A3 US 9615205 W US9615205 W US 9615205W WO 9709039 A3 WO9709039 A3 WO 9709039A3
Authority
WO
WIPO (PCT)
Prior art keywords
rxr
vitamin
composition
acid
9cra
Prior art date
Application number
PCT/US1996/015205
Other languages
French (fr)
Other versions
WO1997009039A2 (en
Inventor
Cary Weinberger
Sutisak Kitareewan
Original Assignee
Us Gov Health & Human Serv
Cary Weinberger
Sutisak Kitareewan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv, Cary Weinberger, Sutisak Kitareewan filed Critical Us Gov Health & Human Serv
Priority to AU71160/96A priority Critical patent/AU7116096A/en
Publication of WO1997009039A2 publication Critical patent/WO1997009039A2/en
Publication of WO1997009039A3 publication Critical patent/WO1997009039A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

RXR is a nuclear receptor that plays a central role in cell signaling by pairing with a host of other receptors. Previously, 9-cis-retinoic acid (9cRA) was defined as a potent RXR activator. Here we describe Vitamin F (phytanoic acid), a unique RXR effector identified from organic extracts of bovine serum by following RXR-dependent transcriptional activity, and compositions containing Vitamin F.
PCT/US1996/015205 1995-09-08 1996-09-06 Composition comprising vitamin f WO1997009039A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU71160/96A AU7116096A (en) 1995-09-08 1996-09-06 Composition comprising vitamin f

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US344395P 1995-09-08 1995-09-08
US60/003,443 1995-09-08

Publications (2)

Publication Number Publication Date
WO1997009039A2 WO1997009039A2 (en) 1997-03-13
WO1997009039A3 true WO1997009039A3 (en) 2001-09-13

Family

ID=21705901

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/015205 WO1997009039A2 (en) 1995-09-08 1996-09-06 Composition comprising vitamin f

Country Status (2)

Country Link
AU (1) AU7116096A (en)
WO (1) WO1997009039A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001066080A1 (en) * 2000-03-07 2001-09-13 Avon Products, Inc. Methods using phytol to improve the appearance of skin and compositions for such methods
US6784207B2 (en) 2000-08-04 2004-08-31 Roche Vitamins Inc. Phytanic acid derivative compositions
DE10253042A1 (en) * 2002-11-14 2004-06-03 Wacker-Chemie Gmbh Cosmetic preparation containing a complex of cyclodextrin and vitamin F.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835505A (en) * 1981-08-27 1983-03-02 Masatoshi Takenouchi Mechanism for solar ray inductive device
US5221796A (en) * 1991-02-12 1993-06-22 Fuji Photo Film Co., Ltd. Glycerol derivatives
US5236950A (en) * 1988-02-18 1993-08-17 Toyama Chemical Co., Ltd. Process for hair growth

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835505A (en) * 1981-08-27 1983-03-02 Masatoshi Takenouchi Mechanism for solar ray inductive device
US5236950A (en) * 1988-02-18 1993-08-17 Toyama Chemical Co., Ltd. Process for hair growth
US5221796A (en) * 1991-02-12 1993-06-22 Fuji Photo Film Co., Ltd. Glycerol derivatives

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BARAUD, J. ET AL.: "Rôle de la cha*ne phytyle sur certains symptomes d'avitaminose E chez le poussin.", ARCH. SCI. PHYSIOL, vol. 23, no. 4, 1969, pages 437 - 51, XP000611600 *
BARAUD, J. ET AL.: "Rôle de l'acide phytanique et du phytol chez les poussins en avitaminose e.", C.R.ACAD. SCI. PARIS, SER D, vol. 268, no. 9, 1969, pages 1339 - 41, XP000611606 *
HIDIROGLOU: "Fate of 14C-phytol Administered Orally to Sheep", CAN J. PHYSIOL. PHARM, vol. 50, no. 5, 1972, pages 458 - 62, XP002020042 *
KRYWAWYCH ET AL.: "The Effect of Phytol upon Skeletal Muscle Damage in Vitamin E-Deficient Animals", J. INHER. METAB. DIS., vol. 8, no. suppl 2, 1985, pages 111 - 112, XP002020040 *
WEBER: "Ueber den Mechanismus der Reactivierung der Bersteinsäure-cytochrom-c-Reductase durch die Vitamine E und K.", HELV. CHIM. ACTA, vol. 41, no. 118, 1958, pages 1038 - 1052, XP002020041 *

Also Published As

Publication number Publication date
WO1997009039A2 (en) 1997-03-13
AU7116096A (en) 1997-03-27

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