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WO1997029077A1 - Derives amides substitues - Google Patents

Derives amides substitues Download PDF

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Publication number
WO1997029077A1
WO1997029077A1 PCT/JP1997/000302 JP9700302W WO9729077A1 WO 1997029077 A1 WO1997029077 A1 WO 1997029077A1 JP 9700302 W JP9700302 W JP 9700302W WO 9729077 A1 WO9729077 A1 WO 9729077A1
Authority
WO
WIPO (PCT)
Prior art keywords
group represented
hydrocarbyl
single bond
sch2
ch2s
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP1997/000302
Other languages
English (en)
Japanese (ja)
Inventor
Yoshikazu Iwasawa
Tetsuya Aoyama
Kumiko Kawakami
Sachie Arai
Toshihiko Satoh
Yoshiaki Monden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Original Assignee
Banyu Phamaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Phamaceutical Co Ltd filed Critical Banyu Phamaceutical Co Ltd
Priority to AU16190/97A priority Critical patent/AU1619097A/en
Publication of WO1997029077A1 publication Critical patent/WO1997029077A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des composés représentés par la formule générale (1), certains de leurs sels ou esters galéniques et des agents antitumoraux les utilisant comme principes actifs. Dans cette formule générale, Ar1 représente un groupe aryle ou un groupe aromatique hétérocyclique. Ar représente un groupe se représentant au moyen des formules spécifiques (A) ou (B), Ar?2 et Ar3¿ représentant chacun un aryle ou hétéroaryle. A1 représente un hydrocarbyle en C¿1-4. A?2 représente un hydrocarbyle en C¿1-8?. m est un entier valant de 1 à 6. n et p sont l'un et l'autre un entier valant de 0 à 3. Q?1¿ représente une liaison simple, un groupe représenté par -CH¿2?O-, -OCH2-, CH2S-, -SCH2- ou un hydrocarbyle en C1-6. Q?2¿ représente une liaison simple ou un groupe représenté par -(CH¿2?)m- ou -(CH2)n-W-(CH2)p. Q?3¿ représente une liaison simple, un oxygène, un soufre, un méthylène, un vinylène, ou un groupe représenté par -CO-, -NH-, -COO-, -OCO-, -CH¿2?CH2-, -OCH2-, -SCH2-, -CH2O-, -CH2S-, -NHCO- ou -CONH-. R?1¿ représente un alkyle inférieur et W représente un oxygène, un soufre, un vinylène ou un éthynylène.
PCT/JP1997/000302 1996-02-07 1997-02-07 Derives amides substitues Ceased WO1997029077A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU16190/97A AU1619097A (en) 1996-02-07 1997-02-07 Substituted amide derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8/45501 1996-02-07
JP4550196 1996-02-07

Publications (1)

Publication Number Publication Date
WO1997029077A1 true WO1997029077A1 (fr) 1997-08-14

Family

ID=12721160

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP1997/000302 Ceased WO1997029077A1 (fr) 1996-02-07 1997-02-07 Derives amides substitues

Country Status (2)

Country Link
AU (1) AU1619097A (fr)
WO (1) WO1997029077A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403818B1 (en) 2000-02-28 2002-06-11 Eisai Co., Ltd. Process for producing α-hydroxy-carbonyl compound
WO2017047594A1 (fr) * 2015-09-14 2017-03-23 国立大学法人岐阜大学 Dérivé de nucléoside et utilisation associée

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07138214A (ja) * 1993-02-12 1995-05-30 Banyu Pharmaceut Co Ltd 置換アミド酸誘導体
WO1996005169A1 (fr) * 1994-08-12 1996-02-22 Banyu Pharmaceutical Co., Ltd. Derive d'acide amique n,n-bisubstitue
WO1996005168A1 (fr) * 1994-08-11 1996-02-22 Banyu Pharmaceutical Co., Ltd. Derive d'amide substitue

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07138214A (ja) * 1993-02-12 1995-05-30 Banyu Pharmaceut Co Ltd 置換アミド酸誘導体
WO1996005168A1 (fr) * 1994-08-11 1996-02-22 Banyu Pharmaceutical Co., Ltd. Derive d'amide substitue
WO1996005169A1 (fr) * 1994-08-12 1996-02-22 Banyu Pharmaceutical Co., Ltd. Derive d'acide amique n,n-bisubstitue

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403818B1 (en) 2000-02-28 2002-06-11 Eisai Co., Ltd. Process for producing α-hydroxy-carbonyl compound
WO2017047594A1 (fr) * 2015-09-14 2017-03-23 国立大学法人岐阜大学 Dérivé de nucléoside et utilisation associée
JPWO2017047594A1 (ja) * 2015-09-14 2018-10-11 国立大学法人岐阜大学 ヌクレオシド誘導体及びその利用

Also Published As

Publication number Publication date
AU1619097A (en) 1997-08-28

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