WO1998003510B1 - - Google Patents

Info

Publication number: WO1998003510B1
Authority: WO; WIPO (PCT)
Prior art keywords: compound; stereoisomeric forms; ome; isomers; dimethyl
Prior art date: 1997-07-23

Application number

PCT/US1997/013072

Other languages

English (en)

Other versions

WO1998003510A1 (fr

Filing date

1997-07-23

Publication date

1998-04-02

1997-07-23 Priority to HU0500549A priority Critical patent/HU229024B1/hu

1997-07-23 Priority to EA199900158A priority patent/EA004403B1/ru

1997-07-23 Priority to DE69738197T priority patent/DE69738197T2/de

1997-07-23 Priority to NZ333777A priority patent/NZ333777A/en

1997-07-23 Priority to SK97-99A priority patent/SK286461B6/sk

1997-07-23 Priority to HU0102187A priority patent/HU228962B1/hu

1997-07-23 Priority to IL15016397A priority patent/IL150163A0/xx

1997-07-23 Priority to JP50723398A priority patent/JP4704521B2/ja

1997-07-23 Priority to BR9710544A priority patent/BR9710544A/pt

1997-07-23 Priority to UA99010100A priority patent/UA73913C2/uk

1997-07-23 Priority to DK97936222T priority patent/DK0915880T3/da

1997-07-23 Priority to EP97936222A priority patent/EP0915880B1/fr

1997-07-23 Priority to KR1019997000568A priority patent/KR100548853B1/ko

1997-07-23 Priority to CA002259583A priority patent/CA2259583C/fr

1997-07-23 Priority to PL97331523A priority patent/PL195762B1/pl

1997-07-23 Priority to SI9720045A priority patent/SI9720045B/sl

1997-07-23 Application filed filed Critical

1997-07-23 Priority to RO99-00078A priority patent/RO121272B1/ro

1997-07-23 Priority to AU38942/97A priority patent/AU747708B2/en

1997-07-23 Priority to EEP199900019A priority patent/EE04316B1/xx

1997-07-23 Priority to IL12787197A priority patent/IL127871A0/xx

1998-01-29 Publication of WO1998003510A1 publication Critical patent/WO1998003510A1/fr

1998-04-02 Publication of WO1998003510B1 publication Critical patent/WO1998003510B1/en

1998-12-30 Priority to IL127871A priority patent/IL127871A/en

1999-01-20 Priority to LVP-99-13A priority patent/LV12292B/en

1999-01-21 Priority to NO19990264A priority patent/NO315610B1/no

2002-03-12 Priority to AU23236/02A priority patent/AU773039C/en

2002-06-11 Priority to IL150163A priority patent/IL150163A/en

2004-10-12 Priority to IL164513A priority patent/IL164513A/en

Priority Applications (26)

Application Number	Priority Date	Filing Date	Title
PL97331523A PL195762B1 (pl)	1996-07-24	1997-07-23	Związki [1,5-a]pirazolo-1,3,5-triazynowe, środek farmaceutyczny i zastosowanie związków [1,5-a]pirazolo-1,3,5-triazynowych do wytwarzania leku
DE69738197T DE69738197T2 (de)	1996-07-24	1997-07-23	Azolotriazine und pyrimidine
NZ333777A NZ333777A (en)	1996-07-24	1997-07-23	(1,5-a) pyrazolo and triazole triazines and pyrimidines
SK97-99A SK286461B6 (sk)	1996-07-24	1997-07-23	[1,5-a]-Pyrazolo-1,3,5-triazíny, ich použitie a farmaceutické kompozície na ich báze
HU0102187A HU228962B1 (en)	1996-07-24	1997-07-23	Azolo triazines, pharmaceutical compositions containing them and use of the compounds
IL15016397A IL150163A0 (en)	1996-07-24	1997-07-23	Azolo triazines and pyrimidines
JP50723398A JP4704521B2 (ja)	1996-07-24	1997-07-23	アゾロトリアジン類およびアゾロピリミジン類
BR9710544A BR9710544A (pt)	1996-07-24	1997-07-23	M-todo de tratamento composto e composi-Æo farmac-utica
UA99010100A UA73913C2 (en)	1996-07-24	1997-07-23	Azolo triazines and pyrimidines
DK97936222T DK0915880T3 (da)	1996-07-24	1997-07-23	Azolotriaziner og pyrimidiner
EP97936222A EP0915880B1 (fr)	1996-07-24	1997-07-23	Azolo triazines et pyrimidines
KR1019997000568A KR100548853B1 (ko)	1996-07-24	1997-07-23	아졸로 트리아진 및 피리미딘
CA002259583A CA2259583C (fr)	1996-07-24	1997-07-23	Azolo triazines et pyrimidines
HU0500549A HU229024B1 (en)	1996-07-24	1997-07-23	Azolo-pyridimidines, pharmaceutical compositions containing the same and use thereof
EEP199900019A EE04316B1 (et)	1996-07-24	1997-07-23	Asolotriasiinid ja -pürimidiinid, neid sisaldavadfarmatseutilised kompositsioonid ning nende kasutamine ravimite valmistamiseks
SI9720045A SI9720045B (sl)	1996-07-24	1997-07-23	Azolo triazini in pirimidini
RO99-00078A RO121272B1 (ro)	1996-07-24	1997-07-23	Azolotriazine şi pirimidine
AU38942/97A AU747708B2 (en)	1996-07-24	1997-07-23	Azolo triazines and pyrimidines
EA199900158A EA004403B1 (ru)	1996-07-24	1997-07-23	Производные пиразолотриазинов, фармацевтические композиции, содержащие их, способы лечения
IL12787197A IL127871A0 (en)	1996-07-24	1997-07-23	Azolo triazines and pyrimidines
IL127871A IL127871A (en)	1996-07-24	1998-12-30	PHARMACEUTICAL COMPOSITIONS CONTAINING CRF ANTAGONIST 3-ARYL-PYRAZOLO (AND 1,2,3-TRIAZOLO) [1,5-a]-1,3,5-TRIAZINE DERIVATIVES AND SOME NEW SUCH DERIVATIVES
LVP-99-13A LV12292B (en)	1996-07-24	1999-01-20	TRIANGLE AND PYRIMIDINES AZOL-DERIVATIVES
NO19990264A NO315610B1 (no)	1996-07-24	1999-01-21	Azolotriaziner og -pyrimidiner
AU23236/02A AU773039C (en)	1996-07-24	2002-03-12	Azolo triazines and pyrimidines
IL150163A IL150163A (en)	1996-07-24	2002-06-11	PHARMACEUTICAL COMPOSITIONS COMPRISING PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AND SOME NOVEL SUCH COMPOUNDS
IL164513A IL164513A (en)	1996-07-24	2004-10-12	Pyrazolopyrimidines, pharmaceutical compositions containing them and their use in the preparation of medicaments

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US2329096P	1996-07-24	1996-07-24
US68604796A	1996-07-24	1996-07-24
US08/686,047		1996-07-24
US60/023,290		1996-07-24

Publications (2)

Publication Number	Publication Date
WO1998003510A1 WO1998003510A1 (fr)	1998-01-29
WO1998003510B1 true WO1998003510B1 (fr)	1998-04-02

Family

ID=26696934

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PCT/US1997/013072 WO1998003510A1 (fr)	1996-07-24	1997-07-23	Azolo triazines et pyrimidines

Country Status (17)

Country	Link
EP (2)	EP0915880B1 (fr)
KR (1)	KR100548853B1 (fr)
AR (1)	AR007994A1 (fr)
AT (1)	ATE375344T1 (fr)
AU (1)	AU747708B2 (fr)
CZ (1)	CZ2005613A3 (fr)
DE (1)	DE69738197T2 (fr)
DK (1)	DK0915880T3 (fr)
EA (1)	EA006626B1 (fr)
ES (1)	ES2294800T3 (fr)
HK (1)	HK1052693A1 (fr)
HU (2)	HU228962B1 (fr)
LV (1)	LV12292B (fr)
PT (1)	PT915880E (fr)
RO (1)	RO121272B1 (fr)
TW (2)	TWI238164B (fr)
WO (1)	WO1998003510A1 (fr)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7094782B1 (en)	1996-07-24	2006-08-22	Bristol-Myers Squibb Company	Azolo triazines and pyrimidines
JP2001511813A (ja)	1997-02-18	2001-08-14	ニューロクラインバイオサイエンシーズ，インコーポレイテッド	Ｃｒｆレセプターアンタゴニストおよびそれらに関連する方法
JP4228332B2 (ja) *	1998-01-28	2009-02-25	ブリストル−マイヤーズスクイブファーマカンパニー	アゾロトリアジン類およびアゾロピリミジン類
AU2931099A (en) *	1998-03-06	1999-09-20	Janssen Pharmaceutica N.V.	Crf antagonistic pyrazolo(4,3-b)pyridines
US6509338B1 (en)	1998-06-22	2003-01-21	Bristol-Myers Squibb Company	Pyrazolo[1,5-A]triazine corticotropin releasing factor antagonists
AU755552B2 (en)	1998-11-12	2002-12-12	Neurocrine Biosciences, Inc.	CRF receptor antagonists and methods relating thereto
DK1129096T3 (da)	1998-11-12	2003-09-15	Neurocrine Biosciences Inc	CRF-receptorantagonister og fremgangsmåder, der er relateret dertil
WO2000059907A2 (fr)	1999-04-06	2000-10-12	Du Pont Pharmaceuticals Company	Pyrazolotriazines antagonistes de corticoliberine (crf)
AU4203500A (en)	1999-04-06	2000-10-23	Du Pont Pharmaceuticals Company	Pyrazolopyrimidines as crf antagonists
US6432989B1 (en)	1999-08-27	2002-08-13	Pfizer Inc	Use of CRF antagonists to treat circadian rhythm disorders
ATE318267T1 (de)	1999-09-30	2006-03-15	Neurogen Corp	Einige alkylendiamin-substituierte heterocyclen
HUP0202678A3 (en)	1999-09-30	2004-06-28	Pfizer	Certain alkylene diamine-substituted pyrazolo[1,5,-a]-1,5-pyrimidines and pyrazolo[1,5-a]-1,3,5-triazines, pharmaceutical compositions containing them and their use
CN1377355A (zh) *	1999-09-30	2002-10-30	纽罗杰有限公司	氨基取代的吡唑并[1,5－a]－1,5－嘧啶和吡唑并[1,5－a]－1,3,5－三嗪
EP1293213A1 (fr) *	2000-02-14	2003-03-19	Japan Tobacco Inc.	Agents prophylactiques/therapeutiques contre le stress postoperatoire
US6589952B2 (en)	2000-07-14	2003-07-08	Bristol-Myers Squibb Pharma Company	Imidazo[1,2-a]pyrazines for the treatment of neurological disorders
EP1305637A2 (fr) *	2000-08-02	2003-05-02	Malope Company Limited	Diagnostic et traitement de la dyspepsie non ulcereuse fondes sur l'anomalie de l'axe hypothalamo-hypophyso-surrenalien
EP1368094B1 (fr)	2001-03-13	2007-02-28	Bristol-Myers Squibb Pharma Company	4-(2-butylamino)-2,7-dimethyl-8-(2-methyl-6-methoxypyrid-3-yl) pyrazolo- 1,5-a\|-1,3,5-triazine, ses enantiomeres et sels pharmaceutiquement acceptables en tant que ligands du recepteur de la corticoliberine
KR20030094410A (ko)	2001-05-14	2003-12-11	브리스톨-마이어스 스퀴브 파마 컴파니	부신 피질 자극 호르몬 방출 인자 리간드로서 치환된피라지논, 피리딘 및 피리미딘
AU2002354575A1 (en)	2001-07-12	2003-01-29	Bristol-Myers Squibb Pharma Company	Tetrahydropurinones as corticotropin releasing factor
US7276526B2 (en)	2001-07-13	2007-10-02	Bristol-Myers Squibb Pharma Company	Substituted thiazoles and oxazoles as corticotropin releasing hormone ligands
AU2002340405A1 (en)	2001-11-20	2003-06-10	Bristol-Myers Squibb Pharma Company	3,7-dihydro-purine-2,6-dione derivatives as crf receptor ligands
ES2245772T3 (es)	2002-03-07	2006-01-16	Smithkline Beecham Corporation	Derivados de pirazolopirimidina y pirazolotriazina y composiciones farmaceuticas que los contienen.
PL212090B1 (pl) *	2002-04-26	2012-08-31	Lilly Co Eli	Pochodna triazolu
FR2842809A1 (fr) *	2002-07-26	2004-01-30	Greenpharma Sas	NOUVELLES PYRAZOLO[1,5-a]-1,3,5-TRIAZINES SUBSTITUEES ET LEURS ANALOGUES, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, UTILISATION A TITRE DE MEDICAMENT ET PROCEDES POUR LEUR PREPARATION
FR2850653A1 (fr) *	2003-02-04	2004-08-06	Univ Pasteur	Derives de pyrazolotriazine, procede de preparation et utilisations
US7329658B2 (en)	2003-02-06	2008-02-12	Pfizer Inc	Cannabinoid receptor ligands and uses thereof
US7030145B2 (en)	2003-04-18	2006-04-18	Bristol-Myers Squibb Company	Pyridinyl derivatives for the treatment of depression
US7112585B2 (en)	2003-04-18	2006-09-26	Bristol-Myers Squibb Company	Pyrimidine derivatives as corticotropin releasing factor inhibitors
US7208596B2 (en)	2003-11-25	2007-04-24	Bristol-Myers Squibb Pharma Company	Processes for the preparation of pyrazolo[1,5-a]-1,3,5-triazines and intermediates thereof
US7153961B2 (en)	2003-11-25	2006-12-26	Bristol-Myers Squibb Pharma Co.	Salt and crystalline form thereof of a corticotropin releasing factor receptor antagonist
JP4926720B2 (ja)	2003-12-22	2012-05-09	スミスクラインビーチャム（コーク）リミテッド	Ｃｒｆ受容体アンタゴニストおよびそれらに関連する方法
GB0519957D0 (en)	2005-09-30	2005-11-09	Sb Pharmco Inc	Chemical compound
US20100216798A1 (en) *	2005-07-29	2010-08-26	Astellas Pharma Inc	Fused heterocycles as lck inhibitors
EA015179B1 (ru) *	2006-09-20	2011-06-30	Эли Лилли Энд Компани	Тиазолпиразолопиримидин в качестве антагониста рецептора крф1
AU2007297481B2 (en)	2006-09-20	2012-03-08	Eli Lilly And Company	Thiophene pyrazolopyrimidine compounds
EP2114941B1 (fr)	2006-12-22	2015-03-25	Astex Therapeutics Limited	Composés hétérocycliques bicycliques servant d'inhibiteurs des fgfr
HRP20151398T1 (hr)	2006-12-22	2016-02-12	Astex Therapeutics Limited	Tricikliäśni derivati amina kao inhibitori protein tirozin kinaze
CA2692039C (fr) *	2007-06-13	2019-07-02	Research Development Foundation	Procedes pour le traitement et la prevention de tauopathies et l'amyloidose de beta-amyloide en modulant la signalisation de recepteur crf
GB0720041D0 (en)	2007-10-12	2007-11-21	Astex Therapeutics Ltd	New Compounds
GB0720038D0 (en)	2007-10-12	2007-11-21	Astex Therapeutics Ltd	New compounds
GB0810902D0 (en)	2008-06-13	2008-07-23	Astex Therapeutics Ltd	New compounds
WO2010118207A1 (fr)	2009-04-09	2010-10-14	Schering Corporation	Dérivés pyrazolo[1, 5-a]pyrimidine en tant qu'inhibiteurs de mtor
GB0906472D0 (en)	2009-04-15	2009-05-20	Astex Therapeutics Ltd	New compounds
GB0906470D0 (en)	2009-04-15	2009-05-20	Astex Therapeutics Ltd	New compounds
EP2264035A1 (fr) *	2009-06-04	2010-12-22	Merz Pharma GmbH & Co. KGaA	B antagonistes de la glycine
US9309250B2 (en)	2011-06-22	2016-04-12	Vertex Pharmaceuticals Incorporated	Substituted pyrrolo[2,3-b]pyrazines as ATR kinase inhibitors
AU2012314035B2 (en)	2011-09-30	2016-12-15	Oncodesign S.A.	Macrocyclic LRRK2 kinase inhibitors
GB201210686D0 (en)	2012-06-15	2012-08-01	Holsboermaschmeyer Neurochemie Gmbh	V1B receptor antagonist for use in the treatment of patients having an elevated AVP level and/or an elevated copeptin level
EP2919788A4 (fr)	2012-11-14	2016-05-25	Univ Johns Hopkins	Méthodes et compositions pour le traitement de la schizophrénie
US8871754B2 (en)	2012-11-19	2014-10-28	Irm Llc	Compounds and compositions for the treatment of parasitic diseases
PL2925757T3 (pl)	2012-11-19	2018-06-29	Novartis Ag	Związki i kompozycje do leczenia chorób pasożytniczych
SMT202100425T1 (it)	2012-12-07	2021-09-14	Vertex Pharma	2-ammino-n-(piperidin-1-il-piridin-3-il) pirazolo[1,5alpha]piirimidina-3-carbossiammide come inibitore di atr chinasi
WO2014144663A1 (fr)	2013-03-15	2014-09-18	The Johns Hopkins University	Procédés et compositions pour améliorer la fonction cognitive
ES2881081T3 (es)	2013-03-15	2021-11-26	Agenebio Inc	Procedimientos y composiciones para mejorar la función cognitiva
GB201310782D0 (en)	2013-06-17	2013-07-31	Max Planck Innovation Gmbh	Method for predicting a treatment response to a CRHR1 antagonist and/or V1B antagonist in a patient with depressive and/or anxiety symptoms
SG11201604519PA (en)	2013-12-06	2016-07-28	Vertex Pharma	2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as atr kinase inhibitor, its preparation, different solid forms and radiolabelled derivatives thereof
PL3152212T3 (pl)	2014-06-05	2020-06-15	Vertex Pharmaceuticals Inc.	Radioznakowane pochodne związku 2-amino-6-fluoro-n-[5-fluoro-piridyn-3-ylo]-pirazolo[1,5-a]pirymidino-3-karboksamidu przydatne jako inhibitor kinazy atr, wytwarzanie tego związku i jego różnych postaci stałych
HUE044280T2 (hu)	2014-06-17	2019-10-28	Vertex Pharma	Rosszindulatú daganatok kezelése Chk1- és ATR-gátlók kombinációjával
DK3194405T3 (en)	2014-09-17	2019-04-15	Oncodesign Sa	MACROCYCLIC LRRK2 KINase INHIBITORS
RU2713937C2 (ru)	2014-11-03	2020-02-11	Байер Фарма Акциенгезельшафт	Пиперидинилпиразолопиримидиноны и их применение
CN112843005B (zh)	2015-05-22	2023-02-21	艾吉因生物股份有限公司	左乙拉西坦的延时释放药物组合物
MX395066B (es)	2015-09-30	2025-03-24	Vertex Pharma	Método para tratar cáncer usando una combinación de agentes que dañan el adn e inhibidores de proteína relacionada con ataxia telangiectasia y rad3 (atr).
TWI778050B (zh) *	2017-04-21	2022-09-21	美商醫肯納腫瘤學公司	吲哚ahr抑制劑及其用途
CA3064464A1 (fr)	2017-08-14	2019-02-21	Spruce Biosciences, Inc.	Antagonistes du recepteur du facteur de liberation de la corticotropine
WO2019154294A1 (fr) *	2018-02-06	2019-08-15	江苏恒瑞医药股份有限公司	Dérivé de pyrazolo[1,5-a][1,3,5]triazine-2-amine, son procédé de préparation et son utilisation médicale
PE20212196A1 (es)	2018-10-30	2021-11-16	Kronos Bio Inc	Compuestos, composiciones, y metodos para modular la actividad cdk9
IL300478A (en)	2020-08-12	2023-04-01	Spruce Biosciences Inc	Methods and preparations for the treatment of polycystic ovary syndrome
US11708372B2 (en)	2021-11-19	2023-07-25	Spruce Biosciences, Inc.	Crystalline composition of tildacerfont and methods of use and preparation thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE786611A (fr) *	1971-08-16	1973-01-22	Int Chem & Nuclear Corp	Nouveaux inhibiteurs de xanthine-oxydase et leur procede de preparatio
US3910907A (en) *	1973-07-09	1975-10-07	Icn Pharmaceuticals	Pyrazolo(1,5-a)-1,3,5-triazines
US3995039A (en) *	1975-05-27	1976-11-30	Merck & Co., Inc.	Pyrazolo [1,5-a] [1,3,5] triazines
JPS6157587A (ja) *	1984-08-29	1986-03-24	Shionogi & Co Ltd	縮合複素環誘導体および抗潰瘍剤
US4824834A (en) *	1986-10-31	1989-04-25	Otsuka Pharmaceutical Company, Limited	Pyrazolotriazine compounds
DE3722072A1 (de) *	1987-07-01	1989-01-12	Schering Ag	6,7-dihydro-pyrazolo(1,5-a)(1,3,5) triazin-2-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung als mittel mit herbizider und pflanzenwuchsregulierender wirkung
JP2585462B2 (ja) *	1989-10-25	1997-02-26	株式会社大塚製薬工場	ピラゾロ［１，５―ａ］ピリミジン誘導体
EP0503099A4 (en) *	1990-10-09	1993-12-01	Otsuka Pharmaceutical Co., Ltd.	Pyrimidine derivative, production thereof, and androgen inhibitor
US5484760A (en) *	1990-12-31	1996-01-16	Monsanto Company	Herbicide antidotes as safeners for reducing phytotoxicity resulting from synergistic interaction between herbicides and other pesticides
EP0591528B1 (fr) *	1991-04-22	1998-12-23	Otsuka Pharmaceutical Factory, Inc.	DERIVE DE PYRAZOLO[1,5-a]PYRIMIDINE ET AGENT ANTI-INFLAMMATOIRECONTENANT CE DERIVE
US5356897A (en) *	1991-09-09	1994-10-18	Fujisawa Pharmaceutical Co., Ltd.	3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines
PL176526B1 (pl) *	1992-12-17	1999-06-30	Pfizer	Pirolopirymidyny jako związki o działaniu antagonistów czynnika uwalniającego kortykotropinę
WO1995035298A1 (fr) *	1994-06-21	1995-12-28	Otsuka Pharmaceutical Factory, Inc.	DERIVE DE PYRAZOLO[1,5-a]PYRIMIDINE
EP0770080B1 (fr) *	1995-05-12	1999-07-14	Neurogen Corporation	Derives nouveaux de deazapurine; une nouvelle classe de ligands specifiques de crf1
EE04282B1 (et) *	1996-02-07	2004-04-15	Janssen Pharmaceutica N.V.	Pürasoolpürimidiinid, nende valmistamine ja kasutamine ravimina ning neid sisaldav kompositsioon

1997
- 1997-07-23 HU HU0102187A patent/HU228962B1/hu unknown
- 1997-07-23 HU HU0500549A patent/HU229024B1/hu unknown
- 1997-07-23 AU AU38942/97A patent/AU747708B2/en not_active Expired
- 1997-07-23 KR KR1019997000568A patent/KR100548853B1/ko not_active Expired - Fee Related
- 1997-07-23 EA EA200301042A patent/EA006626B1/ru not_active IP Right Cessation
- 1997-07-23 CZ CZ2005-613A patent/CZ2005613A3/cs unknown
- 1997-07-23 EP EP97936222A patent/EP0915880B1/fr not_active Expired - Lifetime
- 1997-07-23 PT PT97936222T patent/PT915880E/pt unknown
- 1997-07-23 EP EP07015514A patent/EP1908764A1/fr not_active Withdrawn
- 1997-07-23 DE DE69738197T patent/DE69738197T2/de not_active Expired - Lifetime
- 1997-07-23 DK DK97936222T patent/DK0915880T3/da active
- 1997-07-23 WO PCT/US1997/013072 patent/WO1998003510A1/fr active IP Right Grant
- 1997-07-23 AT AT97936222T patent/ATE375344T1/de active
- 1997-07-23 ES ES97936222T patent/ES2294800T3/es not_active Expired - Lifetime
- 1997-07-23 RO RO99-00078A patent/RO121272B1/ro unknown
- 1997-07-24 AR ARP970103368A patent/AR007994A1/es unknown
- 1997-07-25 TW TW092105694A patent/TWI238164B/zh not_active IP Right Cessation
- 1997-07-25 TW TW086110640A patent/TW542827B/zh not_active IP Right Cessation
1999
- 1999-01-20 LV LVP-99-13A patent/LV12292B/en unknown
2003
- 2003-07-02 HK HK03104703.7A patent/HK1052693A1/zh unknown

Publication	Publication Date	Title
WO1998003510B1 (fr)	1998-04-02
EP1008342A3 (fr)	2004-12-29	Composés pharmaceutiquement actifs et liposomes, et leur application
CA2169719A1 (fr)	1995-12-28	Derive de pyrazolo[1,5-a]pyrimidine
CA2017252A1 (fr)	1990-11-23	Composes inhibiteurs de la protease des retrovirus
CA2079703A1 (fr)	1993-04-05	9-amino-6-demethyl-6-desoxytetracyclines substituees en 7
CA2171275A1 (fr)	1996-09-08	Derives du stilbene et compositions pharmaceutiques qui en renferment
KR960702464A (ko)	1996-04-27	Dc-89 유도체[dc-89 derivative]
CA2079692A1 (fr)	1993-04-05	Amino-6-demethyl-6-desoxytetracyclines substituees en 7 et en 9
CA2254833A1 (fr)	1997-12-04	Produit pharmaceutique pour le traitement de troubles neurologiques et neuropsychiatriques
CA2448602A1 (fr)	2002-12-12	Derives de pyrimidine, triazine et pyrazine, recepteurs du glutamate
PL323152A1 (en)	1998-03-16	Derivatives of 1,3-propanodiole as biologically active compounds
CA2195964A1 (fr)	1996-02-08	Pesticides
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CA2181665A1 (fr)	1997-01-22	Melange stabilisateur synergiste
AU3949889A (en)	1990-02-22	The reductive amination of hydroxy-containing compounds
ZA85327B (en)	1985-12-24	Therapeutic compounds
EP1026162A4 (fr)	2001-01-17	Agent anti-rhumatismal
CA2083361A1 (fr)	1993-05-27	Production piscicole
ATE192927T1 (de)	2000-06-15	Neue cephem-derivate
CA2229892A1 (fr)	1997-12-24	Preparations liposomes de derives indolocarbazole
AU1925392A (en)	1993-01-12	A process for the preparation of n-(2,6-dichlorophenyl)-n-phenyl-n-(chloroacetyl)-amine
CA2193348A1 (fr)	1995-12-28	Derives d'alkyldiamines substituees et leur utilisation en tant qu'antagonistes de la tachykinine
CA2302412A1 (fr)	1999-04-08	Derives d'amino-alkylphenols et composes associes
EP0663816A4 (fr)	1996-04-03	Classe nouvelle de derives de phosphocholine a activite fongicide.