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WO1998008499A1 - Compositions biocides - Google Patents

Compositions biocides Download PDF

Info

Publication number
WO1998008499A1
WO1998008499A1 PCT/IB1997/001068 IB9701068W WO9808499A1 WO 1998008499 A1 WO1998008499 A1 WO 1998008499A1 IB 9701068 W IB9701068 W IB 9701068W WO 9808499 A1 WO9808499 A1 WO 9808499A1
Authority
WO
WIPO (PCT)
Prior art keywords
benzoic acid
derivative
animal
composition
animals
Prior art date
Application number
PCT/IB1997/001068
Other languages
English (en)
Inventor
Johannes Adrianus Cornelis Van Ooyen
Original Assignee
Dsm N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm N.V. filed Critical Dsm N.V.
Priority to BR9711977A priority Critical patent/BR9711977A/pt
Priority to CA2265046A priority patent/CA2265046C/fr
Priority to AU40277/97A priority patent/AU4027797A/en
Priority to EP97937758A priority patent/EP0921792A1/fr
Priority to PL331763A priority patent/PL191241B1/pl
Publication of WO1998008499A1 publication Critical patent/WO1998008499A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 

Definitions

  • This invention relates to the use of compositions comprising benzoic acid for use as a medicament for animals, especially pigs, at the same time promoting growth thereof and improving the digestibility of amino acids fed to such animals.
  • animal feed compositions comprising benzoic acid or salts thereof can be used to minimise the emission of odoriferous ammonia from organic wastes, especially animal excrements and manure.
  • benzoic acid can be used instead of relatively expensive antibiotics for such animals and furthermore, such acid/salts have the advantage of being able to promote growth, decrease feed conversion and improve digestibility of amino acids in animal feeds.
  • the present invention is a composition comprising benzoic acid or a derivative of benzoic acid capable of giving rise to free benzoic acid / ' // vivo for use as a medicament for animals Benzoic acid or a derivative thereof capable of giving rise to benzoic acid
  • benzoic acid and derivatives thereof may be suitably administered to the animals as a component of the animal feed or in their drinking water.
  • Specific examples of derivatives of benzoic acid which can give rise to benzoic acid /// vivo include salts of benzoic acid such as eg the alkali metal- alkaline earth metal- and ammonium benzoates.
  • the amount of benzoic acid oi a derivative thereof administered to the animal is suitably such that ii is sufficient to prevent/cure any infection in the animal in its capacity as a biocide
  • Such an amount is suitably in the range from 0.001 - 5% based on the total weight of each feed fed to the animal.
  • This amount may. however, be higher if the function of benzoic acid or a derivative thereof is not only to act as a biocide but also to control the pH of the animal excreta fed on such a diet in order to suppress the emission of ammonia from the excreta.
  • Such higher amounts are suitably limited to a maximum of about 10% based on the total animal feed composition.
  • the benzo e acid/salt functions inter alia as an antibiotic, promotes growth, decreases feed conversion and improves digestibility of amino acids administered in animal feeds.
  • benzoic acid or a derivative thereof may be used in combination with conventional ingredients present in an animal feed composition (diet) such as calcium carbonates, electrolytes such as eg ammonium chloride, proteins such as soya bean meal, wheat, starch, sunflower meal, corn, meat and bone meal, amino acids, animal fat, vitamins and trace minerals.
  • Diet animal feed composition
  • electrolytes such as eg ammonium chloride
  • proteins such as soya bean meal, wheat, starch, sunflower meal, corn, meat and bone meal
  • amino acids animal fat, vitamins and trace minerals.
  • the ratio of the electrolyte to the benzoic acid or a derivative thereof is suitably in the range from 0.5 : 1 to 5 : 1 w/w, preferably from 1.5 : 1 to 3 : I w/w.
  • Benzoic acid or a derivative thereof is particularly effective as a medicament for animals such as poultry, pigs or cattle, especially pigs.
  • *-lt is a blend of Ca (25%) and a mixture of carboxylic acids (75%) - the acids and their amounts in the mixture being formic (30%). acetic (30%) propionic (30%) and citric (10%).

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)

Abstract

L'invention concerne une composition contenant de l'acide benzoïque ou un dérivé de l'acide benzoïque, pouvant donner de l'acide benzoïque libre in vivo et être utilisée comme médicament pour les animaux. Ledit acide ou dérivé fait fonction d'antibiotique, favorise la croissance, diminue l'indice de transformation et améliore la digestibilité des acides aminés administrés dans les aliments pour animaux. L'acide benzoïque ou son dérivé peut être administré à l'animal soit dans sa composition alimentaire, soit dans son eau de boisson. Il est particulièrement efficace chez les porcs.
PCT/IB1997/001068 1996-08-27 1997-08-19 Compositions biocides WO1998008499A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BR9711977A BR9711977A (pt) 1996-08-27 1997-08-19 Composi-{es biocidas
CA2265046A CA2265046C (fr) 1996-08-27 1997-08-19 Compositions biocides
AU40277/97A AU4027797A (en) 1996-08-27 1997-08-19 Biocidal compositions
EP97937758A EP0921792A1 (fr) 1996-08-27 1997-08-19 Compositions biocides
PL331763A PL191241B1 (pl) 1996-08-27 1997-08-19 Sposób pobudzania przyrostu, zmniejszania przemiany pokarmu i poprawienia strawności aminokwasów u świń

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9618008.8A GB9618008D0 (en) 1996-08-27 1996-08-27 Biocidal compositions
GB9618008.8 1996-08-27

Publications (1)

Publication Number Publication Date
WO1998008499A1 true WO1998008499A1 (fr) 1998-03-05

Family

ID=10799084

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB1997/001068 WO1998008499A1 (fr) 1996-08-27 1997-08-19 Compositions biocides

Country Status (9)

Country Link
EP (1) EP0921792A1 (fr)
KR (1) KR100505971B1 (fr)
CN (1) CN1236314A (fr)
AU (1) AU4027797A (fr)
BR (1) BR9711977A (fr)
CA (1) CA2265046C (fr)
GB (1) GB9618008D0 (fr)
PL (1) PL191241B1 (fr)
WO (1) WO1998008499A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1016974C2 (nl) * 2000-12-22 2002-06-25 Dsm Nv BenzoÙzuurdeeltjes.
WO2007079970A1 (fr) 2006-01-13 2007-07-19 Dsm Ip Assets B.V. Nouvelle utilisation d'une composition nutraceutique dans l'alimentation animale
DE102006021392A1 (de) * 2006-05-08 2007-11-15 Ligrana Gmbh Zusammensetzung
JP2009029789A (ja) * 2007-06-26 2009-02-12 Marubeni Nisshin Feed Co Ltd 家畜の尿路感染症予防・治療用組成物
EP2042041A3 (fr) * 2007-06-29 2009-05-13 DSMIP Assets B.V. Utilisation d'acide benzoique et de thymol, eugénol et piperine dans l'alimentation du bétail
DE102016203477A1 (de) 2016-03-03 2017-09-07 Addcon Europe Gmbh Herstellung und Verwendung von Alkalimetalldiformiaten mit mittelkettigen Fettsäurederivaten
WO2020002595A1 (fr) 2018-06-29 2020-01-02 Dsm Ip Assets B.V. Acide benzoïque à libération rapide dans des aliments pour bétail

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104686814A (zh) * 2015-02-16 2015-06-10 广州英赛特生物技术有限公司 对甲基苯甲酸或其盐作为动物饲料添加剂的应用
DE102016101603B3 (de) 2016-01-29 2017-05-11 Hanon Systems Befestigungselement und Verfahren zur Befestigung von Fluidrohrleitungsenden
CN105661046B (zh) * 2016-02-23 2020-12-18 广州英赛特生物技术有限公司 苯甲酸钙在制备动物饲料添加剂中的应用
CN108617856A (zh) * 2018-03-14 2018-10-09 广州英赛特生物技术有限公司 苯甲酸锌在制备动物饲料添加剂中的应用
KR102703901B1 (ko) * 2023-07-26 2024-09-06 남이현 면역력 증강 및 증체량 향상을 위한 돼지 사료 조성물

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1535233A (en) * 1975-02-19 1978-12-13 Plate Kofasil Gmbh Method for preventing aerobic decomposition processes in fermentated fodder
GB2008381A (en) * 1977-11-19 1979-06-06 Basf Ag Animal Feed supplements
GB2109217A (en) * 1981-08-04 1983-06-02 Nitrokemia Ipartelepek Fodder and fodder additives promoting the weight increase of domestic animals and a process for the preparation thereof
WO1993016611A1 (fr) * 1992-02-27 1993-09-02 Kemira Oy Compositions d'agent de conservation pour des produits vegetaux
JPH06298641A (ja) * 1993-02-19 1994-10-25 Takeda Chem Ind Ltd ペットの尿結石症治療・予防剤および治療方法
JPH07228533A (ja) * 1994-02-17 1995-08-29 Jun Kimura 動物用ドリンク剤
EP0683985A1 (fr) * 1994-05-27 1995-11-29 Verdugt B.V. Contrôle de l'émission d'ammoniac et de l'odeur d'excréments d'animaux
WO1996024247A1 (fr) * 1995-02-06 1996-08-15 Kemira Chemicals Oy Nouvelle composition conservatrice
US5603945A (en) * 1993-02-19 1997-02-18 Takeda Chemical Industries, Ltd. Therapeutic/prophylactic agents and method of treating for urinary calculosis in pets

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1535233A (en) * 1975-02-19 1978-12-13 Plate Kofasil Gmbh Method for preventing aerobic decomposition processes in fermentated fodder
GB2008381A (en) * 1977-11-19 1979-06-06 Basf Ag Animal Feed supplements
GB2109217A (en) * 1981-08-04 1983-06-02 Nitrokemia Ipartelepek Fodder and fodder additives promoting the weight increase of domestic animals and a process for the preparation thereof
WO1993016611A1 (fr) * 1992-02-27 1993-09-02 Kemira Oy Compositions d'agent de conservation pour des produits vegetaux
JPH06298641A (ja) * 1993-02-19 1994-10-25 Takeda Chem Ind Ltd ペットの尿結石症治療・予防剤および治療方法
US5603945A (en) * 1993-02-19 1997-02-18 Takeda Chemical Industries, Ltd. Therapeutic/prophylactic agents and method of treating for urinary calculosis in pets
JPH07228533A (ja) * 1994-02-17 1995-08-29 Jun Kimura 動物用ドリンク剤
EP0683985A1 (fr) * 1994-05-27 1995-11-29 Verdugt B.V. Contrôle de l'émission d'ammoniac et de l'odeur d'excréments d'animaux
WO1996024247A1 (fr) * 1995-02-06 1996-08-15 Kemira Chemicals Oy Nouvelle composition conservatrice
WO1996024248A1 (fr) * 1995-02-06 1996-08-15 Kemira Chemicals Oy Composition microbicide et ses emplois

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 9502, Derwent World Patents Index; Class B05, AN 95-011742, XP002046599 *
DATABASE WPI Section Ch Week 9543, Derwent World Patents Index; Class B05, AN 95-332478, XP002046600 *

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1016974C2 (nl) * 2000-12-22 2002-06-25 Dsm Nv BenzoÙzuurdeeltjes.
WO2002051785A1 (fr) * 2000-12-22 2002-07-04 Dsm N.V. Particules d'acide benzoique
WO2007079970A1 (fr) 2006-01-13 2007-07-19 Dsm Ip Assets B.V. Nouvelle utilisation d'une composition nutraceutique dans l'alimentation animale
DE102006021392A1 (de) * 2006-05-08 2007-11-15 Ligrana Gmbh Zusammensetzung
DE102006021392B4 (de) * 2006-05-08 2013-06-27 Ligrana Gmbh Zusammensetzung
JP2009029789A (ja) * 2007-06-26 2009-02-12 Marubeni Nisshin Feed Co Ltd 家畜の尿路感染症予防・治療用組成物
EP2042041A3 (fr) * 2007-06-29 2009-05-13 DSMIP Assets B.V. Utilisation d'acide benzoique et de thymol, eugénol et piperine dans l'alimentation du bétail
RU2400101C2 (ru) * 2007-06-29 2010-09-27 ДСМ АйПи АССЕТС Б.В. Композиция корма для животных
EP2368440A1 (fr) * 2007-06-29 2011-09-28 DSM IP Assets B.V. Additif pour l'alimentation du bétail comprenant un acide organique et une huile essentielle adsorbée
JP2014057591A (ja) * 2007-06-29 2014-04-03 Dsm Ip Assets Bv 飼料添加剤組成物及びその使用
DE102016203477A1 (de) 2016-03-03 2017-09-07 Addcon Europe Gmbh Herstellung und Verwendung von Alkalimetalldiformiaten mit mittelkettigen Fettsäurederivaten
WO2020002595A1 (fr) 2018-06-29 2020-01-02 Dsm Ip Assets B.V. Acide benzoïque à libération rapide dans des aliments pour bétail

Also Published As

Publication number Publication date
CA2265046A1 (fr) 1998-03-05
PL191241B1 (pl) 2006-04-28
KR20000035832A (ko) 2000-06-26
PL331763A1 (en) 1999-08-02
CN1236314A (zh) 1999-11-24
EP0921792A1 (fr) 1999-06-16
CA2265046C (fr) 2010-05-25
AU4027797A (en) 1998-03-19
GB9618008D0 (en) 1996-10-09
KR100505971B1 (ko) 2005-08-05
BR9711977A (pt) 1999-08-24

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