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WO1998011927A1 - Organe d'expulsion destine a faire avancer le bouchon d'une ampoule d'injection et bouchon correspondant - Google Patents

Organe d'expulsion destine a faire avancer le bouchon d'une ampoule d'injection et bouchon correspondant Download PDF

Info

Publication number
WO1998011927A1
WO1998011927A1 PCT/CH1996/000325 CH9600325W WO9811927A1 WO 1998011927 A1 WO1998011927 A1 WO 1998011927A1 CH 9600325 W CH9600325 W CH 9600325W WO 9811927 A1 WO9811927 A1 WO 9811927A1
Authority
WO
WIPO (PCT)
Prior art keywords
stopper
output member
plug
ampoule
connection
Prior art date
Application number
PCT/CH1996/000325
Other languages
German (de)
English (en)
Inventor
Jürg Steck
Christoph Renggli
Original Assignee
Disetronic Licensing Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Disetronic Licensing Ag filed Critical Disetronic Licensing Ag
Priority to PCT/CH1996/000325 priority Critical patent/WO1998011927A1/fr
Publication of WO1998011927A1 publication Critical patent/WO1998011927A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31515—Connection of piston with piston rod

Definitions

  • Output element for feeding a stopper of a spray ampoule and stopper for this.
  • the invention relates to an output member for advancing a stopper of a spray ampoule according to the preamble of claim 1 and a matching stopper according to the preamble of claim 10.
  • Injection vials are essentially hollow cylindrical containers which are closed on one side with a movable piston and on the other side by an outlet piece.
  • Infusion systems are known from the prior art which store the medicament to be administered in a spray ampoule in which the medicament is located between a movable stopper and a piercing membrane.
  • An output member moves the stopper in the direction of the needle, as a result of which medicine is pushed into the catheter through a connecting needle.
  • Stopper retainers for infusion devices are also known in which the driven member can be connected to the stopper in such a way that the stopper has, for example at its rear end, a cylindrical opening into which the driven member can be inserted and connected.
  • the cylindrical opening is a drilled thread so that the ampoule can first be filled using a pull-up rod.
  • the pull-up rod is unscrewed and the ampoule is inserted into the infusion device (pump) and connected to the output member.
  • the dispensing mechanism works in such a way that the threaded rod is rotatable and axially displaceable, while the threaded nut is non-rotatable and axially fixed.
  • the rotating threaded rod is connected to the plug in such a way that a connecting element is placed on the threaded rod, which is rotatable relative to the threaded rod but is axially fixed, so that the threaded rod rotates but not the connecting element in the plug.
  • ampoules which are inserted into an injection device. These ampoules are usually pre-filled, so there is no reason to provide the stopper with a threaded hole for a pull-up rod. If such a prefilled ampoule is now to be inserted into an infusion device, there is no possibility of connecting the output member stopper.
  • the invention seeks to remedy this.
  • the invention has for its object to provide an output member for a stopper, so that a non-positive and / or positive locking connection can be established between the stopper of an ampoule and an output member.
  • the invention has for its object to provide a stopper for non-positive and / or positive connection with an output member according to the invention.
  • the invention solves the problem with an output member having the features of claim 1 and a stopper which has the features of claim 10.
  • FIG. 1 shows a longitudinal section through a prefilled spray ampoule with a stopper without a threaded bore
  • FIG. 2 shows an output member according to the invention with a mandrel for the plug of the spray ampoule according to FIG. 1;
  • FIG. 2a shows an output member according to the invention with a roof-shaped needle for the stopper of the spray ampoule according to FIG. 1; 3 shows a variant of the output member according to the invention with a suction cup;
  • Fig. 4 shows a variant of the inventive output member with an adhesive
  • FIG. 5 shows a partial longitudinal section through a prefilled spray ampoule with a stopper with a magnet
  • FIG. 6 shows an output element according to the invention with a magnet for the plug of the spray ampoule according to FIG. 5;
  • FIG. 7 shows a partial longitudinal section through a prefilled spray ampoule with a stopper with Velcro fastener
  • FIG. 8 shows an output element according to the invention with a Velcro fastener for the stopper of the spray ampoule according to FIG. 7;
  • FIG. 9 shows an output element according to the invention with a self-tapping screw for the stopper of the spray ampoule according to FIG. 1;
  • FIG. 10 shows a partial longitudinal section through a prefilled spray ampoule with a stopper with click closure; and 11 shows an output element according to the invention with a click closure for the stopper of the spray ampoule according to FIG. 10.
  • the output member 1 shown in FIG. 2 is used to advance a stopper 2 shown in FIG. 1 of a spray ampoule 3 for dispensing a liquid medicament 4, the stopper 2 having no bore with an internal thread for receiving a pull-up rod.
  • the end of the output member 1 intended for abutment on the stopper 2 is provided with means 5 which permit a non-positive and / or positive connection to the stopper 2, with the exception of a threaded connection.
  • Elements 5 with a tip are very generally suitable as means 5.
  • the stopper 2 of the spray ampoule 3 is normally made of rubber. It is therefore possible to penetrate the rubber with a pointed object. If the dispensing mechanism is designed in such a way that the threaded rod is non-rotatable and axially displaceable, only the end of the output member facing the plug 2 has to be designed with a tip and the tip pushed into the plug 2. If the delivery mechanism of the infusion system is configured in such a way that its threaded rod is rotatable and axially displaceable, the tip for connecting the output member to the stopper 2 is located at the end of the connecting element facing the stopper 2.
  • the shape of the pointed object is preferably a roof-shaped needle (FIG. 2a).
  • the shape of the roof makes it possible for the needle not to slide in a certain direction when it enters the stopper 2, as would be the case with a one-sided bevel cut.
  • the force that drives the mandrel out of the plug (V) must therefore be smaller than the friction (R ⁇ ) that exists between the mandrel and the rubber compound.
  • the friction must also withstand a water column (W) of a certain size.
  • the power of the water column (W) and displacement of the cathedral (V) are to be added and must be less than the friction between the outer surface of the dome and the rubber stopper (R d ) and between the rubber stopper and the inner wall of the ampoule (R a ):
  • the friction between the rubber stopper and stopper 2 is additionally increased when the outer diameter of the pointed object - as is usual with a tip - increases below the tip, in order then to decrease against the connecting element (FIG. 2a).
  • a roof-shaped needle is ideal, the outside diameter of which decreases below the roof, towards the end opposite the tip.
  • a screw 12 can be provided as a means for connection to the stopper 2.
  • the advantage of a self-tapping screw corresponds to that of a nail compared to a screw, - a separation of the parts connected thereby requires a greater effort.
  • Such a screw connection is expediently primarily used together with a non-rotatable threaded rod, because in the case of a rotatable threaded rod, the screw 12 is welded to a rotatable connecting element, so that in the latter embodiment, the screw 12 could only be screwed into the stopper 2 with additional auxiliary elements.
  • a suction cup 6 can be provided as a means for connection to the plug 2 instead of a Do s or a needle 5.
  • the advantage of this solution compared to a pointed object or a screw is that neither the plug 2 is injured nor the user can injure himself.
  • Another advantage of this type of connection is that the suction cup 6 and thus, depending on the type of connection suction cup threaded rod, the threaded rod (in contrast to solutions which require adhesive) can be reused.
  • the maximum outside diameter of the suction cup 6 is somewhat smaller than the inside diameter of the ampoule.
  • the surface of the stopper 2 should be as smooth as possible.
  • an adhesive 7 can also be provided as a means for connection to the stopper 2.
  • An adhesive 7 is preferably used, which can be connected to different materials.
  • the drug resistance should be guaranteed.
  • the threaded rod will not be used again because a release from the plug 2 is not possible or only under difficult conditions.
  • the adhesive 7 can already be attached to the threaded rod (or on the stopper 2) and secured against drying out with a cover.
  • a magnet 8 can also be provided as a means for connection to the stopper 2. Basically, it is sufficient if either the threaded rod or the plug 2 is magnetic, while the remaining part can be magnetic or just a piece of metal.
  • the magnet 8 - or just a piece of metal - can be in or on the plug 2.
  • the advantage of this version is that the threaded rod can be reused.
  • the threaded rod itself can be magnetic or can be provided with a further magnet 9 (FIG. 5).
  • a Velcro fastener 10, 11 can also be provided as a means for connection to the stopper 2.
  • the advantage of this version is that the threaded rod can be reused.
  • the adhesive mentioned above can be used to attach the two parts of the Velcro fastener 10, 11 to the stopper 2 and to the threaded rod.
  • Common Velcro fasteners are sold under the VELCRO TM brand.
  • a click closure 13, 14 can also be provided as a means for connection to the stopper 2.
  • the threaded rod can also be reused in this embodiment.
  • the click fastener 13, 14 can be realized in various ways. When decoupling plug 2 and threaded rod, it should not be forgotten that plug 2 is at the lowest end of the ampoule when the threaded rod is to be decoupled. It is therefore primarily an axial movement through which the plug 2 and the threaded rod are separated.
  • the click lock 13, 14 consists of a spherical body 13 attached to the threaded rod and a concave receiving body 14 for the spherical body 13 attached to the stopper 2.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un organe d'expulsion (1) destiné à faire avancer le bouchon (2) dans une ampoule d'injection (3) pour administrer un médicament (4) liquide. Le bouchon (2) ne dispose d'aucun orifice avec filetage intérieur destiné à recevoir une tige de traction. L'extrémité de l'organe d'expulsion (1) destinée à être appliquée sur le bouchon (2) est pourvue de moyens (5, 6, 7, 8, 10, 12, 13) permettant une liaison de force et/ou de forme, à l'exception d'une liaison filetée, avec le bouchon (2). Grâce à cette conception, on peut également utiliser sans difficulté, dans un appareil de perfusion, des ampoules préalablement remplies, dont le bouchon (2) est pourvu d'un orifice fileté destiné à recevoir une tige de traction.
PCT/CH1996/000325 1996-09-20 1996-09-20 Organe d'expulsion destine a faire avancer le bouchon d'une ampoule d'injection et bouchon correspondant WO1998011927A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CH1996/000325 WO1998011927A1 (fr) 1996-09-20 1996-09-20 Organe d'expulsion destine a faire avancer le bouchon d'une ampoule d'injection et bouchon correspondant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CH1996/000325 WO1998011927A1 (fr) 1996-09-20 1996-09-20 Organe d'expulsion destine a faire avancer le bouchon d'une ampoule d'injection et bouchon correspondant

Publications (1)

Publication Number Publication Date
WO1998011927A1 true WO1998011927A1 (fr) 1998-03-26

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CH1996/000325 WO1998011927A1 (fr) 1996-09-20 1996-09-20 Organe d'expulsion destine a faire avancer le bouchon d'une ampoule d'injection et bouchon correspondant

Country Status (1)

Country Link
WO (1) WO1998011927A1 (fr)

Cited By (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1078643A1 (fr) * 1999-08-13 2001-02-28 CANE' S.r.l. Appareil pour administrer des médicaments aux malades
WO2002096487A1 (fr) * 2001-05-30 2002-12-05 Acist Medical Systems, Inc. Systeme d'injection medicale
EP1455870B1 (fr) * 2001-12-06 2007-08-08 Novo Nordisk A/S Systeme d'apport medical
EP1897575A3 (fr) * 2000-07-20 2008-03-19 ACIST Medical Systems, Inc. Mécanisme de blocage de piston de seringue
WO2008103175A1 (fr) * 2007-02-22 2008-08-28 M2 Group Holdings, Inc. Pompe pour perfusion portable et à tige de piston souple
US7534226B2 (en) 2005-09-26 2009-05-19 M2 Group Holdings, Inc. Dispensing fluid from an infusion pump system
WO2009153544A1 (fr) * 2008-06-19 2009-12-23 Cilag Gmbh International Auto-injecteur avec moyen de remplissage
US8118781B2 (en) 2006-04-19 2012-02-21 Novo Nordisk A/S Fluid infusion system, a method of assembling such system and drug reservoir for use in the system
US8277414B2 (en) 2004-05-28 2012-10-02 Cilag Gmbh International Injection device
US8313464B2 (en) 2004-05-28 2012-11-20 Cilag Gmbh International Injection device
US8313463B2 (en) 2004-05-28 2012-11-20 Cilag Gmbh International Injection device
US8313465B2 (en) 2004-05-28 2012-11-20 Cilag Gmbh International Injection device
US8317751B2 (en) 2005-04-06 2012-11-27 Cilag Gmbh International Injection device
US8343110B2 (en) 2004-05-28 2013-01-01 Cilag Gmbh International Injection device
US8366669B2 (en) 2005-04-06 2013-02-05 Cilag Gmbh International Injection device
US8551045B2 (en) 2006-04-19 2013-10-08 Novo Nordisk A/S Fluid infusion system, a method of assembling such system and drug reservoir for use in the system
US8834419B2 (en) 2008-06-19 2014-09-16 Cilag Gmbh International Reusable auto-injector
US8834420B2 (en) 2007-05-21 2014-09-16 Asante Solutions, Inc. Illumination instrument for an infusion pump
US8852141B2 (en) 2007-05-21 2014-10-07 Asante Solutions, Inc. Occlusion sensing for an infusion pump
US8852152B2 (en) 2011-02-09 2014-10-07 Asante Solutions, Inc. Infusion pump systems and methods
US8870853B2 (en) 2007-09-06 2014-10-28 Asante Solutions, Inc. Operating a portable medical device
US8894628B2 (en) 2007-09-07 2014-11-25 Asante Solutions, Inc. Activity sensing techniques for an infusion pump system
US8905995B2 (en) 2005-04-06 2014-12-09 Asante Solutions, Inc. Medicine dispensing device
US8939958B2 (en) 2008-06-19 2015-01-27 Cilag Gmbh International Fluid transfer assembly for a syringe
US8945044B2 (en) 2012-07-19 2015-02-03 Asante Solutions, Inc. Infusion pump system and method
US8968236B2 (en) 2005-04-06 2015-03-03 Cilag Gmbh International Injection device
US9028453B2 (en) 2008-06-19 2015-05-12 Cilag Gmbh International Reusable auto-injector
US9028451B2 (en) 2006-06-01 2015-05-12 Cilag Gmbh International Injection device
US9072833B2 (en) 2006-06-01 2015-07-07 Cilag Gmbh International Injection device
US9114209B2 (en) 2005-11-08 2015-08-25 Bigfoot Biomedical, Inc. Method and system for manual and autonomous control of an infusion pump
US9295777B2 (en) 2002-11-05 2016-03-29 Bigfoot Biomedical, Inc. Disposable wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device
US9308319B2 (en) 2002-11-05 2016-04-12 Bigfoot Biomedical, Inc. Wearable insulin dispensing device, and a combination of such a device and a programming controller
US9358346B2 (en) 2005-08-30 2016-06-07 Cilag Gmbh International Needle assembly for a prefilled syringe system
US9381302B2 (en) 2007-09-07 2016-07-05 Bigfoot Biomedical, Inc. User profile backup system for an infusion pump device
US9415158B2 (en) 2007-09-07 2016-08-16 Bigfoot Biomedical, Inc. Power management techniques for an infusion pump system
US9427523B2 (en) 2012-12-10 2016-08-30 Bigfoot Biomedical, Inc. Infusion pump system and method
US9440021B2 (en) 2007-05-21 2016-09-13 Bigfoot Biomedical, Inc. Removable controller for an infusion pump
US9446186B2 (en) 2013-03-01 2016-09-20 Bigfoot Biomedical, Inc. Operating an infusion pump system
US9446187B2 (en) 2013-06-03 2016-09-20 Bigfoot Biomedical, Inc. Infusion pump system and method
US9457141B2 (en) 2013-06-03 2016-10-04 Bigfoot Biomedical, Inc. Infusion pump system and method
US9517301B2 (en) 2005-09-26 2016-12-13 Bigfoot Biomedical, Inc. Operating an infusion pump system
US9517300B2 (en) 2012-07-20 2016-12-13 Bigfoot Biomedical, Inc. Pump system and method
US9539388B2 (en) 2005-09-26 2017-01-10 Bigfoot Biomedical, Inc. Operating an infusion pump system
US9561324B2 (en) 2013-07-19 2017-02-07 Bigfoot Biomedical, Inc. Infusion pump system and method
US9610404B2 (en) 2011-09-07 2017-04-04 Bigfoot Biomedical, Inc. Method for occlusion detection for an infusion pump system
US9629901B2 (en) 2014-07-01 2017-04-25 Bigfoot Biomedical, Inc. Glucagon administration system and methods
US9649441B2 (en) 2005-04-06 2017-05-16 Cilag Gmbh International Injection device (bayonet cap removal)
US9675758B2 (en) 2004-05-28 2017-06-13 Cilag Gmbh International Injection device
US9675757B2 (en) 2004-05-28 2017-06-13 Cilag Gmbh International Injection device
US9682194B2 (en) 2008-06-19 2017-06-20 Cilag Gmbh International Re-useable auto-injector with filling means
WO2017134144A1 (fr) 2016-02-02 2017-08-10 Novo Nordisk A/S Procédé de formation d'une cartouche de médicament et cartouche de médicament formée par le procédé
US9731080B2 (en) 2005-04-06 2017-08-15 Cilag Gmbh International Injection device
US9757520B2 (en) 2006-06-01 2017-09-12 Cilag Gmbh International Injection device
US9770558B2 (en) 2005-09-27 2017-09-26 Cilag Gmbh International Auto-injection device with needle protecting cap having outer and inner sleeves
USD809134S1 (en) 2016-03-10 2018-01-30 Bigfoot Biomedical, Inc. Infusion pump assembly
US9878097B2 (en) 2015-04-29 2018-01-30 Bigfoot Biomedical, Inc. Operating an infusion pump system
US9895493B2 (en) 2004-05-28 2018-02-20 Cilag Gmbh International Injection device
US9919096B2 (en) 2014-08-26 2018-03-20 Bigfoot Biomedical, Inc. Infusion pump system and method
US10064993B2 (en) 2005-09-26 2018-09-04 Bigfoot Biomedical, Inc. Dispensing fluid from an infusion pump system
US10137246B2 (en) 2014-08-06 2018-11-27 Bigfoot Biomedical, Inc. Infusion pump assembly and method
USD836769S1 (en) 2016-12-12 2018-12-25 Bigfoot Biomedical, Inc. Insulin delivery controller
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IT201700090397A1 (it) * 2017-08-04 2019-02-04 Medesy Srl Siringa per odontoiatria
US10426896B2 (en) 2016-09-27 2019-10-01 Bigfoot Biomedical, Inc. Medicine injection and disease management systems, devices, and methods
US10449294B1 (en) 2016-01-05 2019-10-22 Bigfoot Biomedical, Inc. Operating an infusion pump system
US10569015B2 (en) 2013-12-02 2020-02-25 Bigfoot Biomedical, Inc. Infusion pump system and method
US10709849B2 (en) 2013-06-11 2020-07-14 Cilag Gmbh International Guide for an injection device
US10799646B2 (en) 2013-06-11 2020-10-13 Cilag Gmbh International Injection device
US10987468B2 (en) 2016-01-05 2021-04-27 Bigfoot Biomedical, Inc. Operating multi-modal medicine delivery systems
US11096624B2 (en) 2016-12-12 2021-08-24 Bigfoot Biomedical, Inc. Alarms and alerts for medication delivery devices and systems
US11123492B2 (en) 2013-06-11 2021-09-21 Cilag Gmbh International Injection device
US11173255B2 (en) 2013-06-11 2021-11-16 Cilag Gmbh International Injection device
US11260169B2 (en) 2013-03-14 2022-03-01 Bigfoot Biomedical, Inc. Infusion pump system and methods
US11389088B2 (en) 2017-07-13 2022-07-19 Bigfoot Biomedical, Inc. Multi-scale display of blood glucose information
US11865299B2 (en) 2008-08-20 2024-01-09 Insulet Corporation Infusion pump systems and methods
US12106837B2 (en) 2016-01-14 2024-10-01 Insulet Corporation Occlusion resolution in medication delivery devices, systems, and methods

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CH268694A (de) * 1950-04-17 1950-05-31 Ag Mediglass Injektionsspritze und Verfahren zur Herstellung derselben.
DE874506C (de) * 1951-10-23 1953-04-23 Bodo Engelberts Injektionsspritze
US2706984A (en) * 1953-03-19 1955-04-26 Gloacchino Lipari Plunger assembly and disposable medicament cartridge for use therewith
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GB2202747A (en) * 1987-01-17 1988-10-05 Dr William Ducat Syringes
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Cited By (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1078643A1 (fr) * 1999-08-13 2001-02-28 CANE' S.r.l. Appareil pour administrer des médicaments aux malades
EP1897575A3 (fr) * 2000-07-20 2008-03-19 ACIST Medical Systems, Inc. Mécanisme de blocage de piston de seringue
US7566326B2 (en) 2000-07-20 2009-07-28 Acist Medical Systems, Inc. Syringe plunger locking mechanism
WO2002096487A1 (fr) * 2001-05-30 2002-12-05 Acist Medical Systems, Inc. Systeme d'injection medicale
US7308300B2 (en) 2001-05-30 2007-12-11 Acist Medical Systems, Inc. Medical injection system
US9901671B2 (en) 2001-05-30 2018-02-27 Acist Medical Systems, Inc. Medical injection system
EP1455870B1 (fr) * 2001-12-06 2007-08-08 Novo Nordisk A/S Systeme d'apport medical
US9308319B2 (en) 2002-11-05 2016-04-12 Bigfoot Biomedical, Inc. Wearable insulin dispensing device, and a combination of such a device and a programming controller
US9295777B2 (en) 2002-11-05 2016-03-29 Bigfoot Biomedical, Inc. Disposable wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device
US9757512B2 (en) 2002-11-05 2017-09-12 Bigfoot Biomedical, Inc. Wearable insulin dispensing device, and a combination of such a device and a programming controller
US9675758B2 (en) 2004-05-28 2017-06-13 Cilag Gmbh International Injection device
US9675757B2 (en) 2004-05-28 2017-06-13 Cilag Gmbh International Injection device
US8277414B2 (en) 2004-05-28 2012-10-02 Cilag Gmbh International Injection device
US8313464B2 (en) 2004-05-28 2012-11-20 Cilag Gmbh International Injection device
US8313463B2 (en) 2004-05-28 2012-11-20 Cilag Gmbh International Injection device
US8313465B2 (en) 2004-05-28 2012-11-20 Cilag Gmbh International Injection device
US9895493B2 (en) 2004-05-28 2018-02-20 Cilag Gmbh International Injection device
US8343110B2 (en) 2004-05-28 2013-01-01 Cilag Gmbh International Injection device
US10105483B2 (en) 2005-04-06 2018-10-23 Bigfoot Biomedical, Inc. Medicine dispensing device
US9649441B2 (en) 2005-04-06 2017-05-16 Cilag Gmbh International Injection device (bayonet cap removal)
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