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WO1998017804A3 - ANTIGENE D'HELICOBACTER (η-GLUTAMYLTRANSFERASE) ET SEQUENCES CODANT CE DERNIER - Google Patents

ANTIGENE D'HELICOBACTER (η-GLUTAMYLTRANSFERASE) ET SEQUENCES CODANT CE DERNIER Download PDF

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Publication number
WO1998017804A3
WO1998017804A3 PCT/EP1997/005727 EP9705727W WO9817804A3 WO 1998017804 A3 WO1998017804 A3 WO 1998017804A3 EP 9705727 W EP9705727 W EP 9705727W WO 9817804 A3 WO9817804 A3 WO 9817804A3
Authority
WO
WIPO (PCT)
Prior art keywords
glutamyltransferase
same
sequences encoding
helicobacter antigen
helicobacter
Prior art date
Application number
PCT/EP1997/005727
Other languages
English (en)
Other versions
WO1998017804A2 (fr
Inventor
Catherine Chevalier
Jean-Michel Thiberge
Agnes Labigne
Original Assignee
Pasteur Institut
Inst Nat Sante Rech Med
Catherine Chevalier
Jean-Michel Thiberge
Agnes Labigne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut, Inst Nat Sante Rech Med, Catherine Chevalier, Jean-Michel Thiberge, Agnes Labigne filed Critical Pasteur Institut
Priority to EP97945852A priority Critical patent/EP0939800A2/fr
Priority to AU51199/98A priority patent/AU5119998A/en
Publication of WO1998017804A2 publication Critical patent/WO1998017804A2/fr
Publication of WO1998017804A3 publication Critical patent/WO1998017804A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Cette invention concerne un polynucléotide purifié d'hélicobacter qui se caractérise par le fait qu'il comprend dans sa structure une séquence de codage destinée à une protéine chargée d'une activité catalytique de transfert, par exemple une activité de transfert des restes de η-glutamyl ou pour ses fragments; ou bien qu'il est capable d'être hybridé avec la séquence nucléotidique d'environ 2Kb qui est introduite dans le plasmide pILL308.
PCT/EP1997/005727 1996-10-17 1997-10-17 ANTIGENE D'HELICOBACTER (η-GLUTAMYLTRANSFERASE) ET SEQUENCES CODANT CE DERNIER WO1998017804A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP97945852A EP0939800A2 (fr) 1996-10-17 1997-10-17 ANTIGENE D'HELICOBACTER (gamma-GLUTAMYLTRANSFERASE) ET SEQUENCES CODANT CE DERNIER
AU51199/98A AU5119998A (en) 1996-10-17 1997-10-17 A (helicobacter) antigen (gamma-glutamyltransferase) and sequences encoding the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2866496P 1996-10-17 1996-10-17
US60/028,664 1996-10-17

Publications (2)

Publication Number Publication Date
WO1998017804A2 WO1998017804A2 (fr) 1998-04-30
WO1998017804A3 true WO1998017804A3 (fr) 1998-07-16

Family

ID=21844747

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1997/005727 WO1998017804A2 (fr) 1996-10-17 1997-10-17 ANTIGENE D'HELICOBACTER (η-GLUTAMYLTRANSFERASE) ET SEQUENCES CODANT CE DERNIER

Country Status (3)

Country Link
EP (1) EP0939800A2 (fr)
AU (1) AU5119998A (fr)
WO (1) WO1998017804A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6190667B1 (en) 1998-06-30 2001-02-20 Institut Pasteur Methods of inhibiting Helicobacter pylori
WO2000001825A1 (fr) * 1998-07-01 2000-01-13 Institut Pasteur ANTIGENE D'HELICOBACTER (η-GLUTAMYLTRANSPEPTIDASE) ET SEQUENCES CODANT POUR CET ANTIGENE
AU3205000A (en) * 1999-02-19 2000-09-04 Astrazeneca Ab Expression of helicobacter polypeptides in pichia pastoris
DE10020034A1 (de) * 2000-04-22 2001-10-31 Fischer Peter Mittel zur Diagnose und Therapie von Karzinomen
CN1321652A (zh) * 2000-04-29 2001-11-14 上海博德基因开发有限公司 一种新的多肽——人含gamma－谷氨酰转肽酶特征序列片段的蛋白10和编码这种多肽的多核苷酸
JP3823268B2 (ja) * 2002-05-30 2006-09-20 独立行政法人科学技術振興機構 ヘリコバクター・ピロリの細胞死誘導剤
EP1789094B1 (fr) 2004-08-13 2014-12-10 MARSHALL, Barry J. Vecteur d'administration bactérien
US8029777B2 (en) 2004-08-13 2011-10-04 Marshall Barry J Helicobacter system and uses thereof
AU2013273605B2 (en) * 2006-10-19 2016-04-14 Hepyvaxx Gmbh Novel method for treating H.pylori infections
EP1913955A1 (fr) 2006-10-19 2008-04-23 Gerhard, Markus Nouveau méthode pour le traitement des infections par H. pylori

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MEGRAUD F. ET AL: "Characterization of 'Campylobacter pyloridis' by culture. Enzymatic profile, and protein content", J. CLIN. MICROBIOL., 1985, 22/6 (1007-1010), USA, XP002062104 *
PIETROKOVSKI S: "Searching databases of conserved sequence regions by aligning protein multiple-alignments [published erratum appears in Nucleic Acids Res 1996 Nov 1;24(21):4372]", NUCLEIC ACIDS RES, OCT 1 1996, 24 (19) P3836-45, ENGLAND, XP002062262 *
TOMB JF ET AL: "The complete genome sequence of the gastric pathogen Helicobacter pylori [see comments]", NATURE, AUG 7 1997, 388 (6642) P539-47, ENGLAND, XP002062106 *

Also Published As

Publication number Publication date
AU5119998A (en) 1998-05-15
WO1998017804A2 (fr) 1998-04-30
EP0939800A2 (fr) 1999-09-08

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