WO1998018491A1 - Procedes et compositions pour la complementation alimentaire - Google Patents
Procedes et compositions pour la complementation alimentaire Download PDFInfo
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- WO1998018491A1 WO1998018491A1 PCT/US1997/019564 US9719564W WO9818491A1 WO 1998018491 A1 WO1998018491 A1 WO 1998018491A1 US 9719564 W US9719564 W US 9719564W WO 9818491 A1 WO9818491 A1 WO 9818491A1
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Classifications
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/32—Thymopoietins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Definitions
- suppressor T-lymphocytes block the development of effector B and T lymphocytes.
- Specific suppressor T-lymphocytes have now been demonstrated to play a large role in tolerance to many proteins, both in antibody and cell-mediated immune responses.
- genetic unresponsiveness to some antigens is due to the greater stimulation of suppressor T-lymphocytes than of helper T-lymphocytes by these antigens.
- the present invention provides a composition consisting essentially of thymus enzymatic polypeptide fractions, thymus extract, raw spleen, raw lymph, raw bone marrow, raw pituitary, vitamins A, D, C, E, B-l, B-2, B-6 and B-12, folic acid, niacinamide, biotin, pantothenic acid, calcium, iodine, magnesium, copper, zinc, selenium, potassium, manganese, chromium, boron, hesperidin, inositol, citrus bioflavinoid, choline, betaine HC1, octacosanol, para amino benzoic acid, rutin, trypsin, bromelain, papain, Echinacea angustifolia extract, Iris versicolor extract, Hydrastis canadensis extract, L-lysine, L-arginine, L-cysteine, L-hist
- the present invention also provides methods for enhancing athletic performance in a subject, comprising administering the composition of the present invention to the subject.
- the administration of the composition of the present invention to a subject results in an increase in total red blood cells in the subject, as demonstrated by increased hematocrit, thereby providing increased oxygen transport in the subject.
- administration of the compositions of the present invention to a subject results in a more rapid flushing of lactic acid from the muscles, providing a shorter recovery time after athletic activity. The increase in red blood cells and shorter recovery time allow for enhancement of the subject's athletic performance.
- compositions of the present invention provide components in combinations that are different from previously known compositions, in a delivery system for faster absorption by the body.
- Vitamin B-l Thiamine Mononitrate 10 mg
- Example 1 The composition in the dosage amounts of Example 1 is used to supplement the diet of a patient chronically infected with Hepatitis C virus. After continued dietary supplementation, the patient no longer tests positive for active Hepatitis C virus infection.
Landscapes
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Abstract
L'invention concerne une composition comprenant des facteurs dérivés du thymus et des cofacteurs enzymatiques, lesdits facteurs dérivés du thymus pouvant être de l'extrait de thymus, des facteurs polypeptidiques enzymatiques thymiques, de la thymosine, de la thymopoïétine et le facteur humoral thymique et les cofacteurs enzymatiques pouvant être les vitamines A, C, D, E, B-1, B-2, B-6, B-12, des minéraux. Ladite composition peut également comprendre des acides aminés tels que l'arginine, la cystéine, l'histidine, l'ornithine, l'isoleucine, la leucine, la thréonine, la tyrosine, la valine, la phénylalanine et la méthionine. Elle peut également contenir des facteurs glandulaires tels que la rate brute, la lymphe brute, la moelle osseuse brute et l'hypophyse brute. L'invention porte aussi sur des méthodes d'augmentation des taux sériques de thymosine alpha 1 chez un sujet; d'activation du système immunitaire d'un sujet par l'augmentation des taux sériques de thymosine alpha 1 chez un sujet; de traitement d'une maladie auto-immune tels que le lupus érythémateux, la sclérose en plaques et la polyarthrite rhumatoïde chez un sujet; de traitement d'une infection virale induite par un virus tel qu'un virus de l'hépatite A, un virus de l'hépatite B, l'herpèsvirus, le virus de l'hépatite C et un virus de l'immunodéficience humain; et d'augmentation des performances athlétiques chez un sujet par l'augmentation de l'hématocrite et la réduction du temps de guérison, tous ces procédés consistant à administrer au sujet les compositions de l'invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002270223A CA2270223A1 (fr) | 1996-10-28 | 1997-10-28 | Procedes et compositions pour la complementation alimentaire |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2940396P | 1996-10-28 | 1996-10-28 | |
| US60/029,403 | 1996-10-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO1998018491A1 true WO1998018491A1 (fr) | 1998-05-07 |
Family
ID=21848824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US1997/019564 WO1998018491A1 (fr) | 1996-10-28 | 1997-10-28 | Procedes et compositions pour la complementation alimentaire |
Country Status (2)
| Country | Link |
|---|---|
| CA (1) | CA2270223A1 (fr) |
| WO (1) | WO1998018491A1 (fr) |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000025764A3 (fr) * | 1998-10-30 | 2000-07-13 | Merck Patent Gmbh | Compositions de traitement et de prevention de maladies cardio-vasculaires |
| US6180139B1 (en) * | 1998-12-04 | 2001-01-30 | Viva America Marketing, Inc. | Composition and method for treating nonalcoholic steatohepatitis |
| EP1146878A4 (fr) * | 1998-02-26 | 2002-12-04 | Timothy Cochran | Compositions biochimiques utilisees dans des traitements pour l'homme |
| EP1127572A3 (fr) * | 2000-02-25 | 2003-05-02 | Basf Aktiengesellschaft | Utilisation de flavones dans le traitement de maladies induites par cyclooxygenase-2 |
| JP2004002284A (ja) * | 2001-11-30 | 2004-01-08 | Ezaki Glico Co Ltd | リウマチの症状改善用飲食品および医薬 |
| KR100420560B1 (ko) * | 2001-03-10 | 2004-03-02 | 임시웅 | 포도당과 아미노산의 상승작용에 의한 관절염 및관절손상의 예방 및 치료제 |
| GB2396809A (en) * | 2003-01-03 | 2004-07-07 | Vitabiotics Ltd | Composition for the treatment of HIV and AIDS |
| WO2005000331A3 (fr) * | 2003-06-04 | 2005-05-26 | Mucosal Therapeutics Inc | Methodes et compositions permettant de traiter et de prevenir des troubles degeneratifs des articulations |
| WO2008050363A3 (fr) * | 2006-10-27 | 2008-06-26 | Sigma Tau Ind Farmaceuti | Utilisation de thymosine alpha 1 pour la préparation d'un médicament destiné au traitement thérapeutique et préventif de maladies autoimmunes |
| US7452916B2 (en) | 1993-06-11 | 2008-11-18 | The Board Of Trustees Of The Leland Stanford Junior University | Enhancement of vascular function by modulation of endogenous nitric oxide production or activity |
| US7618941B2 (en) | 1999-04-23 | 2009-11-17 | Rhode Island Hospital | Treating degenerative joint disorders with tribonectins |
| US7910092B2 (en) | 2006-03-10 | 2011-03-22 | Tecnogen S.P.A. | Use of the long pentraxin PTX3 for the prevention or treatment of viral diseases |
| US8337828B2 (en) * | 2006-05-02 | 2012-12-25 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of thymosin alpha 1, alone or in combination with PTX3 or ganciclovir, for the treatment of cytomegalovirus infection |
| US8557764B2 (en) | 2007-01-26 | 2013-10-15 | The Regents Of The University Of Colorado, A Body Corporate | Methods of modulating immune function |
| US8957031B2 (en) | 2007-10-23 | 2015-02-17 | Regents Of The University Of Colorado, A Body Corporate | Competitive inhibitors of invariant chain expression and/or ectopic clip binding |
| US9359404B2 (en) | 2011-12-01 | 2016-06-07 | Scott & White Healthcare | Methods and products for treating preeclampsia and modulating blood pressure |
| JP2016198052A (ja) * | 2015-04-10 | 2016-12-01 | 味の素株式会社 | アミノ酸含有組成物 |
| US10716821B2 (en) | 2013-07-22 | 2020-07-21 | Université Du Québec A Chicoutimi | Use of plant extracts against herpes simplex virus |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4698221A (en) * | 1982-11-06 | 1987-10-06 | Bayer Aktiengesellschaft | Vaccines containing fat soluble vitamins, zinc compounds and selenium compounds |
| US4826680A (en) * | 1985-10-23 | 1989-05-02 | Dr. Kurt Mulli Nachf. Gmbh & Co. Kg | Pharmaceutical composition containing thymus extract fractions |
| US4863898A (en) * | 1986-02-06 | 1989-09-05 | Albion International, Inc. | Amino acid chelated compositions for delivery to specific biological tissue sites |
-
1997
- 1997-10-28 CA CA002270223A patent/CA2270223A1/fr not_active Abandoned
- 1997-10-28 WO PCT/US1997/019564 patent/WO1998018491A1/fr active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4698221A (en) * | 1982-11-06 | 1987-10-06 | Bayer Aktiengesellschaft | Vaccines containing fat soluble vitamins, zinc compounds and selenium compounds |
| US4826680A (en) * | 1985-10-23 | 1989-05-02 | Dr. Kurt Mulli Nachf. Gmbh & Co. Kg | Pharmaceutical composition containing thymus extract fractions |
| US4863898A (en) * | 1986-02-06 | 1989-09-05 | Albion International, Inc. | Amino acid chelated compositions for delivery to specific biological tissue sites |
Cited By (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7452916B2 (en) | 1993-06-11 | 2008-11-18 | The Board Of Trustees Of The Leland Stanford Junior University | Enhancement of vascular function by modulation of endogenous nitric oxide production or activity |
| EP1146878A4 (fr) * | 1998-02-26 | 2002-12-04 | Timothy Cochran | Compositions biochimiques utilisees dans des traitements pour l'homme |
| WO2000025764A3 (fr) * | 1998-10-30 | 2000-07-13 | Merck Patent Gmbh | Compositions de traitement et de prevention de maladies cardio-vasculaires |
| US6180139B1 (en) * | 1998-12-04 | 2001-01-30 | Viva America Marketing, Inc. | Composition and method for treating nonalcoholic steatohepatitis |
| US7018652B2 (en) | 1998-12-04 | 2006-03-28 | Viva America Marketing, Inc. | Composition and method for treating nonalcoholic steatohepatitis |
| US7618941B2 (en) | 1999-04-23 | 2009-11-17 | Rhode Island Hospital | Treating degenerative joint disorders with tribonectins |
| US8680057B2 (en) | 1999-04-23 | 2014-03-25 | Rhode Island Hospital | Tribonectins |
| US8026346B2 (en) * | 1999-04-23 | 2011-09-27 | Rhode Island Hospital | Tribonectins |
| EP1127572A3 (fr) * | 2000-02-25 | 2003-05-02 | Basf Aktiengesellschaft | Utilisation de flavones dans le traitement de maladies induites par cyclooxygenase-2 |
| KR100420560B1 (ko) * | 2001-03-10 | 2004-03-02 | 임시웅 | 포도당과 아미노산의 상승작용에 의한 관절염 및관절손상의 예방 및 치료제 |
| JP2004002284A (ja) * | 2001-11-30 | 2004-01-08 | Ezaki Glico Co Ltd | リウマチの症状改善用飲食品および医薬 |
| GB2396809A (en) * | 2003-01-03 | 2004-07-07 | Vitabiotics Ltd | Composition for the treatment of HIV and AIDS |
| WO2005000331A3 (fr) * | 2003-06-04 | 2005-05-26 | Mucosal Therapeutics Inc | Methodes et compositions permettant de traiter et de prevenir des troubles degeneratifs des articulations |
| US7910092B2 (en) | 2006-03-10 | 2011-03-22 | Tecnogen S.P.A. | Use of the long pentraxin PTX3 for the prevention or treatment of viral diseases |
| US8268304B2 (en) | 2006-03-10 | 2012-09-18 | Sigma-Tau Industrie Farmaceutiche Riunite Spa | Use of the long pentraxin PTX3 for the prevention or treatment of viral diseases |
| US8337828B2 (en) * | 2006-05-02 | 2012-12-25 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of thymosin alpha 1, alone or in combination with PTX3 or ganciclovir, for the treatment of cytomegalovirus infection |
| JP2010507650A (ja) * | 2006-10-27 | 2010-03-11 | シグマ − タウ インデュストリエ ファーマシューティッツェ リウニーテ ソシエタ ペル アチオニ | 自己免疫疾患の予防及び治療用の薬剤を調製するためのチモシンアルファ１の使用 |
| WO2008050363A3 (fr) * | 2006-10-27 | 2008-06-26 | Sigma Tau Ind Farmaceuti | Utilisation de thymosine alpha 1 pour la préparation d'un médicament destiné au traitement thérapeutique et préventif de maladies autoimmunes |
| US8557764B2 (en) | 2007-01-26 | 2013-10-15 | The Regents Of The University Of Colorado, A Body Corporate | Methods of modulating immune function |
| US8957031B2 (en) | 2007-10-23 | 2015-02-17 | Regents Of The University Of Colorado, A Body Corporate | Competitive inhibitors of invariant chain expression and/or ectopic clip binding |
| US10420813B2 (en) | 2007-10-23 | 2019-09-24 | The Regents Of The University Of Colorado, A Body Corporate | Competitive inhibitors of invariant chain expression and/or ectopic clip binding |
| US9359404B2 (en) | 2011-12-01 | 2016-06-07 | Scott & White Healthcare | Methods and products for treating preeclampsia and modulating blood pressure |
| US10716821B2 (en) | 2013-07-22 | 2020-07-21 | Université Du Québec A Chicoutimi | Use of plant extracts against herpes simplex virus |
| JP2016198052A (ja) * | 2015-04-10 | 2016-12-01 | 味の素株式会社 | アミノ酸含有組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2270223A1 (fr) | 1998-05-07 |
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