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WO1998024812A3 - Polypeptides et polynucleotides a6la5a12 et procedes en relation avec leur utilisation - Google Patents

Polypeptides et polynucleotides a6la5a12 et procedes en relation avec leur utilisation Download PDF

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Publication number
WO1998024812A3
WO1998024812A3 PCT/US1997/022403 US9722403W WO9824812A3 WO 1998024812 A3 WO1998024812 A3 WO 1998024812A3 US 9722403 W US9722403 W US 9722403W WO 9824812 A3 WO9824812 A3 WO 9824812A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
a6la5a12
methods
polynucleotides
use therefor
Prior art date
Application number
PCT/US1997/022403
Other languages
English (en)
Other versions
WO1998024812A2 (fr
Inventor
Gregory S Kelner
Derek Thomas Chalmers
Richard A Maki
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Priority to AU55950/98A priority Critical patent/AU5595098A/en
Publication of WO1998024812A2 publication Critical patent/WO1998024812A2/fr
Publication of WO1998024812A3 publication Critical patent/WO1998024812A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne des compositions et des procédés permettant de renforcer la survie des cellules. De telles compositions comprennent des polypeptides A6LA5A12, et certaines de leurs variantes, qui inhibent la dégénérescence neuronale provoquée par le stress. Ces polypeptides conviennent, par exemple à la prévention et au traitement de divers états liés aux délabrements oxydatifs et à la dégénérescence neuronale.
PCT/US1997/022403 1996-12-03 1997-12-03 Polypeptides et polynucleotides a6la5a12 et procedes en relation avec leur utilisation WO1998024812A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU55950/98A AU5595098A (en) 1996-12-03 1997-12-03 A6la5a12 polypeptides and polynucleotides and methods of use therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76000496A 1996-12-03 1996-12-03
US08/760,004 1996-12-03

Publications (2)

Publication Number Publication Date
WO1998024812A2 WO1998024812A2 (fr) 1998-06-11
WO1998024812A3 true WO1998024812A3 (fr) 1999-08-05

Family

ID=25057752

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/022403 WO1998024812A2 (fr) 1996-12-03 1997-12-03 Polypeptides et polynucleotides a6la5a12 et procedes en relation avec leur utilisation

Country Status (2)

Country Link
AU (1) AU5595098A (fr)
WO (1) WO1998024812A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111748015B (zh) * 2020-05-25 2022-04-22 昆明医科大学 一种活性多肽os-ll11及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995026363A1 (fr) * 1994-03-29 1995-10-05 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Neurotrophine-6: un nouveau membre de la famille des neurotrophines
WO1995033480A1 (fr) * 1994-06-07 1995-12-14 The Government Of The United States Of America, Re Facteur derive de l'epithelium pigmentaire: caracterisation, organisation genomique et sequence de son gene
WO1996014083A1 (fr) * 1994-11-04 1996-05-17 Polymun Scientific Immunbiologische Forschung Gmbh Application de superoxide dismutase dans des liposomes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995026363A1 (fr) * 1994-03-29 1995-10-05 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Neurotrophine-6: un nouveau membre de la famille des neurotrophines
WO1995033480A1 (fr) * 1994-06-07 1995-12-14 The Government Of The United States Of America, Re Facteur derive de l'epithelium pigmentaire: caracterisation, organisation genomique et sequence de son gene
WO1996014083A1 (fr) * 1994-11-04 1996-05-17 Polymun Scientific Immunbiologische Forschung Gmbh Application de superoxide dismutase dans des liposomes

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
EMBL Nucleotide Database IBI Hinxton, Cambridge, acession number D81002, 06/02/1996, Fujiwara T., 'large scale sequencing project at Otsuke GEN Research Institute' *
EMBL Nucleotide Database IBI Hinxton, Cambridge, acession number D81594, 07/02/1996, Fujiwara T., 'large scale sequencing project at Otsuke GEN Research Institute' *
EMBL Nucleotide Database IBI Hinxton, Cambridge, acession number W02135, 25/04/1996, Hillier et al. 'The WashU-Merck EST Project' *
EMBL Nucleotide Database IBI Hinxton, Cambridge, acession number W32450, 13/05/1996, Hillier et al. 'The WashU-Merck EST Project' *
EMBL Nucleotide Database IBI Hinxton, Cambridge, acession number W40991, 21/05/1996, Marra M. et al, 'The WashU-HHMI Mouse EST Project' *
EMBL Nucleotide Database IBI Hinxton, Cambridge, acession number W55796, 06/06/1996, Marra M. et al, 'The WashU-HHMI Mouse EST Project' *
EMBL Nucleotide Database IBI Hinxton, Cambridge, acession number W71836, 20/06/1996, Marra M. et al, 'The WashU-HHMI Mouse EST Project' *
EMBL Nucleotide Database IBI Hinxton, Cambridge, acession number W82193, 27/06/1996, Marra M. et al, 'The WashU-HHMI Mouse EST Project' *

Also Published As

Publication number Publication date
AU5595098A (en) 1998-06-29
WO1998024812A2 (fr) 1998-06-11

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