[go: up one dir, main page]

WO1999051744A3 - Antagoniste du recepteur de l'interleukine-1 et ses utilisations - Google Patents

Antagoniste du recepteur de l'interleukine-1 et ses utilisations Download PDF

Info

Publication number
WO1999051744A3
WO1999051744A3 PCT/US1999/004291 US9904291W WO9951744A3 WO 1999051744 A3 WO1999051744 A3 WO 1999051744A3 US 9904291 W US9904291 W US 9904291W WO 9951744 A3 WO9951744 A3 WO 9951744A3
Authority
WO
WIPO (PCT)
Prior art keywords
interleukin
receptor antagonist
nucleic acids
polypeptide sequences
polynucleotide
Prior art date
Application number
PCT/US1999/004291
Other languages
English (en)
Other versions
WO1999051744A2 (fr
Inventor
John Ford
Ann Pace
Original Assignee
Hyseq Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hyseq Inc filed Critical Hyseq Inc
Priority to IL13857699A priority Critical patent/IL138576A0/xx
Priority to CA002326066A priority patent/CA2326066A1/fr
Priority to JP2000542457A priority patent/JP2002510492A/ja
Priority to AU34495/99A priority patent/AU769262B2/en
Priority to EP99916115A priority patent/EP1068321A2/fr
Priority to US09/348,942 priority patent/US6337072B1/en
Publication of WO1999051744A2 publication Critical patent/WO1999051744A2/fr
Publication of WO1999051744A3 publication Critical patent/WO1999051744A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention porte sur de nouveaux acides nucléiques, sur les nouvelles séquences de polypeptides codées par eux, et sur leurs utilisations. Ces nouveaux polynucléotides et ces nouvelles séquences de polypeptides se sont avérées constituer un nouvel antagoniste du récepteur de l'interleukine-1.
PCT/US1999/004291 1998-04-03 1999-04-05 Antagoniste du recepteur de l'interleukine-1 et ses utilisations WO1999051744A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IL13857699A IL138576A0 (en) 1998-04-03 1999-04-05 A novel interleukin-1 receptor antagonist and uses thereof
CA002326066A CA2326066A1 (fr) 1998-04-03 1999-04-05 Antagoniste du recepteur de l'interleukine-1 et ses utilisations
JP2000542457A JP2002510492A (ja) 1998-04-03 1999-04-05 インターロイキン−１レセプターアンタゴニストおよびその使用
AU34495/99A AU769262B2 (en) 1998-04-03 1999-04-05 A interleukin-1 receptor antagonist and uses thereof
EP99916115A EP1068321A2 (fr) 1998-04-03 1999-04-05 Antagoniste du recepteur de l'interleukine-1 et ses utilisations
US09/348,942 US6337072B1 (en) 1998-04-03 1999-07-07 Interleukin-1 receptor antagonist and recombinant production thereof

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US5501098A 1998-04-03 1998-04-03
US09/055,010 1998-04-03
US7990998A 1998-05-15 1998-05-15
US09/079,909 1998-05-15
US8236498A 1998-05-20 1998-05-20
US09/082,364 1998-05-20
US9981898A 1998-06-19 1998-06-19
US09/099,818 1998-06-19
US12769898A 1998-07-31 1998-07-31
US09/127,698 1998-07-31
US22959199A 1999-01-13 1999-01-13
US09/229,591 1999-01-13
US25137099A 1999-02-17 1999-02-17
US09/251,370 1999-02-17

Publications (2)

Publication Number Publication Date
WO1999051744A2 WO1999051744A2 (fr) 1999-10-14
WO1999051744A3 true WO1999051744A3 (fr) 2000-03-30

Family

ID=27568093

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/004291 WO1999051744A2 (fr) 1998-04-03 1999-04-05 Antagoniste du recepteur de l'interleukine-1 et ses utilisations

Country Status (6)

Country Link
EP (1) EP1068321A2 (fr)
JP (1) JP2002510492A (fr)
AU (1) AU769262B2 (fr)
CA (1) CA2326066A1 (fr)
IL (1) IL138576A0 (fr)
WO (1) WO1999051744A2 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ505881A (en) 1998-01-09 2003-05-30 Immunex Corp IL-1 delta DNA and polypeptides
US6541623B1 (en) * 1998-04-03 2003-04-01 Hyseq, Inc. Interleukin—1 receptor antagonist and uses thereof
AU6296899A (en) * 1998-10-08 2000-04-26 Zymogenetics Inc. Interleukin-1 homolog
EP2319929A1 (fr) * 1998-12-23 2011-05-11 Genentech, Inc. Polypeptides de type IL-1
US6339141B1 (en) 1999-05-20 2002-01-15 Hycey Inc. Interleukin-1 Hy2 materials and methods
ATE390482T1 (de) 1999-05-20 2008-04-15 Nuvelo Inc Interleukin-1 hy2. mittel und verfahren
US6627199B1 (en) 1999-07-09 2003-09-30 Amgen Inc Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family
AU6219400A (en) * 1999-07-16 2001-02-05 Interleukin Genetics, Inc. The il-1l1 gene and polypeptide products
AU6517800A (en) 1999-08-04 2001-03-05 Amgen, Inc. Ntr3, a member of the tnf-receptor supergene family
MXPA02001264A (es) 1999-08-04 2002-07-22 Amgen Inc Fhm, nuevo miembro de la familia de supergenes de ligando de factor de necrosis tumoral.
WO2001089549A2 (fr) * 2000-05-22 2001-11-29 Hyseq, Inc. Utilisations therapeutiques d'antagoniste du recepteur de l'il-1
CA2454824A1 (fr) * 2001-07-25 2003-02-06 Nuvelo, Inc. Traitement de troubles concernant les cellules immunitaires et les cellules b
CN1960744A (zh) * 2004-02-27 2007-05-09 瓦克斯咨询公司 肽IL1β和TNFα以及应用其治疗的方法
WO2009062339A1 (fr) 2007-11-14 2009-05-22 General Regeneratives, Ltd. Procédés d'utilisation d'un antagoniste des récepteurs de l'interleukine 1 en tant qu'un agent myéloprotecteur
CN101690801B (zh) 2009-10-26 2012-08-01 上海交通大学 白细胞介素-1受体拮抗剂的用途及其药物组合物
US20160000936A1 (en) 2014-06-10 2016-01-07 Abbvie Inc. Biomarkers for inflammatory disease and methods of using same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991017249A1 (fr) * 1990-05-01 1991-11-14 Cetus Corporation Antagoniste d'interleucine-1 et utilisation de celui-ci
WO1998047921A1 (fr) * 1997-04-21 1998-10-29 Schering Corporation Cytokines de mammifere; reactifs et procedes connexes
WO1999035268A1 (fr) * 1998-01-09 1999-07-15 Immunex Corporation Adn codant il-1 delta et polypeptides il-1 delta

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148009B1 (ko) 1988-05-27 1998-08-01 그래고리 비. 아보트 인터루킨-1 억제제

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991017249A1 (fr) * 1990-05-01 1991-11-14 Cetus Corporation Antagoniste d'interleucine-1 et utilisation de celui-ci
WO1998047921A1 (fr) * 1997-04-21 1998-10-29 Schering Corporation Cytokines de mammifere; reactifs et procedes connexes
WO1999035268A1 (fr) * 1998-01-09 1999-07-15 Immunex Corporation Adn codant il-1 delta et polypeptides il-1 delta

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J.J. MULERO ET AL: "iL-1HY1: A novel Interleukin-1 Receptor Antagonist gene", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 263, no. 3, 5 October 1999 (1999-10-05), ACADEMIC PRESS INC. ORLANDO, FL., US, pages 702 - 706, XP002126222, ISSN: 0006-291X *

Also Published As

Publication number Publication date
AU3449599A (en) 1999-10-25
EP1068321A2 (fr) 2001-01-17
IL138576A0 (en) 2001-10-31
CA2326066A1 (fr) 1999-10-14
JP2002510492A (ja) 2002-04-09
AU769262B2 (en) 2004-01-22
WO1999051744A2 (fr) 1999-10-14

Similar Documents

Publication Publication Date Title
WO2001053312A8 (fr) Nouveaux acides nucleiques et polypeptides
WO2001053455A3 (fr) Nouveaux acides nucleiques et polypeptides associes
WO2001075067A3 (fr) Nouveaux acides nucleiques et polypeptides
WO2001057188A3 (fr) Nouveaux acides nucleiques et polypeptides
WO2001057190A3 (fr) Acides nucleiques et polypeptides
WO2002022660A3 (fr) Noveaux acides nucleiques et polypeptides
WO2001066689A3 (fr) Nouveaux acides nucleiques et polypeptides
WO2002031111A3 (fr) Acides nucleiques et polypeptides
WO2002059260A3 (fr) Nouveaux acides nucleiques et polypeptides
WO2001002571A3 (fr) Nouvel antagoniste du recepteur d'interleukin-1 et ses utilisations
WO2003054152A3 (fr) Nouveaux acides nucleiques et polypeptides
WO1999051744A3 (fr) Antagoniste du recepteur de l'interleukine-1 et ses utilisations
WO2002081731A3 (fr) Nouveaux acides nucleiques et polypeptides
WO2004080148A3 (fr) Nouveaux acides nucleiques et polypeptides
EP1162264A3 (fr) Récepteur de l'hormone chimérique
WO2003029271A3 (fr) Nouveaux acides nucleiques et polypeptides
ZA988675B (en) Amino-terminally truncated rantes as chemokine antagonists.
WO2002018424A3 (fr) Nouveaux acides nucleiques et polypeptides
WO2001079449A3 (fr) Acides nucleiques et polypeptides nouveaux
WO2002044340A3 (fr) Nouveaux acides nucleiques et polypeptides
WO2001055339A3 (fr) Nouveaux acides nucleiques foetaux et polypeptides
WO2001075093A8 (fr) Nouveaux acides nucleiques et polypeptides
WO2002077180A3 (fr) Nouveaux acides nucleiques et nouveaux polypeptides
AU8953401A (en) A novel polypeptide, a human protein 16.83 ftsh and the polynucleotide encoding the polypeptide
EP1591448A3 (fr) Nouveaux acides nucleiques et polypeptides

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 138576

Country of ref document: IL

WWE Wipo information: entry into national phase

Ref document number: 09348942

Country of ref document: US

AK Designated states

Kind code of ref document: A2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 09576008

Country of ref document: US

ENP Entry into the national phase

Ref country code: JP

Ref document number: 2000 542457

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: PA/a/2000/009515

Country of ref document: MX

ENP Entry into the national phase

Ref document number: 2326066

Country of ref document: CA

Ref country code: CA

Ref document number: 2326066

Kind code of ref document: A

Format of ref document f/p: F

NENP Non-entry into the national phase

Ref country code: KR

WWE Wipo information: entry into national phase

Ref document number: 1999916115

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 34495/99

Country of ref document: AU

WWP Wipo information: published in national office

Ref document number: 1999916115

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWG Wipo information: grant in national office

Ref document number: 34495/99

Country of ref document: AU