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WO1999060989A2 - Preparation pour le traitement de la peau humaine et des cheveux contenant une combinaison speciale de principes actifs, et utilisation de cette combinaison de principe actif - Google Patents

Preparation pour le traitement de la peau humaine et des cheveux contenant une combinaison speciale de principes actifs, et utilisation de cette combinaison de principe actif Download PDF

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Publication number
WO1999060989A2
WO1999060989A2 PCT/EP1999/003362 EP9903362W WO9960989A2 WO 1999060989 A2 WO1999060989 A2 WO 1999060989A2 EP 9903362 W EP9903362 W EP 9903362W WO 9960989 A2 WO9960989 A2 WO 9960989A2
Authority
WO
WIPO (PCT)
Prior art keywords
preparation according
hair
glycoprotein
active ingredient
ingredient combination
Prior art date
Application number
PCT/EP1999/003362
Other languages
German (de)
English (en)
Other versions
WO1999060989A3 (fr
Inventor
Detlef Hollenberg
Ullrich Bernecker
Original Assignee
Henkel Kommanditgesellschaft Auf Aktien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Kommanditgesellschaft Auf Aktien filed Critical Henkel Kommanditgesellschaft Auf Aktien
Priority to EP99953283A priority Critical patent/EP1079795A2/fr
Priority to AU42625/99A priority patent/AU4262599A/en
Priority to CA002333544A priority patent/CA2333544A1/fr
Priority to JP2000550450A priority patent/JP2002516263A/ja
Publication of WO1999060989A2 publication Critical patent/WO1999060989A2/fr
Publication of WO1999060989A3 publication Critical patent/WO1999060989A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988—Honey; Royal jelly, Propolis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures

Definitions

  • the invention relates to preparations with a special combination of active ingredients consisting of biotin and at least one glycoprotein for the treatment of human skin and hair and the use of this combination of active ingredients.
  • an active ingredient combination consisting of biotin and at least one glycoprotein increases protein production in human cells when administered topically.
  • an active ingredient combination consisting of biotin and at least one glycoprotein increases protein production in human cells when administered topically.
  • a first subject of the invention is therefore preparations for the treatment of human skin and hair, characterized in that they contain an active ingredient combination consisting of biotin and at least one glycoprotein.
  • the first component of the active ingredient combination according to the invention is biotin.
  • Biotin means (3aS, 4S, 6aR) -2-oxohexahydrothienol [3,4 - ⁇ - t] -imidazole-4-valeric acid.
  • the compound is also called vitamin H or vitamin B 7 .
  • the active ingredient combination according to the invention contains at least one glycoprotein.
  • Glycoproteins are compounds that contain carbohydrates and protein in the same molecule.
  • glycoproteins of plant origin are preferred according to the invention, the glycoprotein in particular originating from a primary plant cell wall.
  • glycoproteins from soybeans, rice, oats, wheat, potatoes, peaches, almonds, mushrooms and peas have proven to be particularly suitable according to the invention.
  • Glycoproteins from soybeans are particularly preferred according to the invention. Hydroxyproline-rich glycoproteins or extensins, arabinogalactan proteins and proline-rich proteins can be obtained from the primary cell wall of soybeans be won. About 20-30% by weight of the dry mass of the primary soybean cell wall consists of these three components.
  • glycoproteins used according to the invention preferably contain arabinose, galactose, mannose, glucose and fucose as the carbohydrate component.
  • Arabinose and galactose are preferred carbohydrates.
  • An inventively particularly suitable glycoprotein is obtainable under the name Phytodermin ® commercial product.
  • the preparations according to the invention preferably contain biotin in amounts of 0.000001-0.5% by weight, based on the entire preparation. Amounts of 0.000005-0.05% by weight, in particular 0.00001-0.01% by weight, are particularly preferred.
  • glycoproteins are contained in the preparations according to the invention preferably in amounts of 0.0001-5% by weight, in particular 0.001-1% by weight, also based on the entire preparation.
  • the active ingredient combination according to the invention can in principle be incorporated into all customary hair and skin treatment compositions, provided that this is not precluded by known instabilities.
  • the biotin is unstable in combination with strong oxidizing agents.
  • Preparations with such incompatibilities should not be excluded in principle in the context of the present invention. Rather, according to the invention, it may well be possible in this case to pack one of the incompatible components separately and to add them to the preparation only immediately before use.
  • the preparations according to the invention also contain at least one penetration aid.
  • Penetration aids which can be used according to the invention are, for example, polyethylene glycols with molar masses of about 200 to 45,000, in particular about 400, Glycols, urea and glucose as well as glycerin, propylene glycol monoethyl ether, carbonates, hydrogen carbonates, guanidines, as well as primary, secondary and tertiary phosphates.
  • Preferred penetration aids are the polyethylene glycols, propylene glycols, butylene glycols, urea and glucose.
  • the preparations according to the invention preferably contain the penetration aids in amounts of 0.1-15% by weight, based on the entire preparation. Quantities of 0.1-10% by weight are preferred for the skin application area and amounts of 0.1-15% by weight are preferred for the hair application area. In both cases, amounts of approximately 0.1-5% by weight are particularly preferred.
  • the agents according to the invention contain a protein hydrolyzate.
  • this includes both the protein hydrolyzates themselves and their condensation products with fatty acids and quaternized protein hydrolyzates.
  • Preferred protein hydrolyzates are elastin, collagen, keratin, milk protein, soy protein, almond protein, pea protein, rice protein and wheat protein hydrolyzates. Vegetable protein hydrolyzates are particularly preferred.
  • those protein hydrolyzates which have a high proportion of the amino acids hydroxyproline and proline are particularly suitable according to the invention.
  • the protein hydrolyzates are preferably present in the agents according to the invention in amounts of 0.05-5% by weight, based on the total agent.
  • the preparations according to the invention contain a further vitamin component selected from panthenol, tocopherol and vitamin A and their precursors and derivatives.
  • panthenol which can be used according to the invention are, in particular, the esters and ethers of panthenol and cationically derivatized panthenols.
  • Individual representatives are, for example, panthenol triacetate, panthenol monoethyl ether and its monoacetate and the cationic panthenol derivatives disclosed in WO 92/13829.
  • Panthenol itself is preferred within this group.
  • Panthenol and its derivatives are preferably present in the agents according to the invention in amounts of 0.05-10% by weight, based on the total agent. Amounts of 0.1-5% by weight are particularly preferred.
  • Tocopherol and its derivatives which include in particular the esters such as the acetate, the nicotinate, the phosphate and the succinate, derivatives are preferably contained in the preparations according to the invention in amounts of 0.05-1% by weight, based on the preparation as a whole .
  • vitamin A acid and its esters vitamin A aldehyde and vitamin A alcohol and its esters such as palmitate and acetate are suitable as vitamin A components.
  • the preparations according to the invention preferably contain the vitamin A component in amounts of 0.05-1% by weight, based on the entire preparation.
  • the preparations according to the invention contain a plant extract.
  • extracts are usually produced by extracting the entire plant. In individual cases, however, it may also be preferred to produce the extracts exclusively from flowers and / or leaves of the plant.
  • the extracts from almond, aloe vera, coconut, mango, apricot, lime, wheat, kiwi, melon and green tea are particularly suitable for the use according to the invention.
  • Water, alcohols, water-alcohol mixtures and CO 2 can be used as extractants for the production of the plant extracts mentioned.
  • the alcohols lower alcohols such as ethanol and isopropanol, but in particular polyhydric alcohols such as ethylene glycol and propylene glycol, are preferred, both as the sole extracting agent and in a mixture with water.
  • Plant extracts based on water / propylene glycol in a ratio of 1:10 to 10: 1 have proven to be particularly suitable.
  • the plant extracts can be used both in pure and in diluted form. If they are used in dilute form, they usually contain about 2 to 80% by weight of active substance and, as a solvent, the extractant or mixture of extractants used in their extraction.
  • mixtures of several, in particular two, different plant extracts in the agents according to the invention may be preferred.
  • Honey extracts are obtained in an analogous manner to the plant extracts and usually contain 1 to 10% by weight, in particular 3 to 5% by weight, of active substance.
  • Water / propylene glycol mixtures can also be preferred extraction agents here.
  • Plant extracts are used in agents according to the invention preferably in amounts of 0.1-20% by weight, in particular in amounts of 0.2-8% by weight. Amounts of 0.5-5% by weight can be very particularly preferred. These quantities are on the one hand based on the total agent according to the invention, on the other hand on the plant extract in the form in which it is added to the agent. As already stated above, this can be both a pure plant extract and a solution with usually 2-80% by weight of active substance.
  • the preparations according to the invention preferably also contain a film former.
  • Ionic and in particular nonionic polymers are particularly suitable as film formers.
  • Preferred nonionic polymers are polyvinyl pyrrolidone and vinyl pyrrolidone / vinyl acetate copolymers (for example the products Luviskol ® K 30, K90, NA 64 and VA 37), and polysiloxanes (such as the commercial products Dow Corning 345, 190, 193, 200, 245, 246 , 1401 and 1403).
  • preferred cationic polymers are quaternized cellulose ethers such as for example the commercial product Polymer JR ® 400, polysiloxanes with quaternary groups such as Dow Corning DC ® 929, dimethyldiallylammonium chloride polymers such as Merquat ® 100, acrylamide-dimethyl diallyl ammonium chloride copolymers, such as Merquat ® 550, quaternized with diethyl sulfate dimethylaminoethyl Vinylpyrrolidone copolymers such as Gafquat ® 734 and 755, vinylpyrrolidone-imidazolinium methochloride copolymers such as the commercial products of the Luviquat ® series and quaternized polyvinyl alcohol.
  • quaternized cellulose ethers such as for example the commercial product Polymer JR ® 400, polysiloxanes with quaternary groups such as Dow Corning DC ® 929, dimethyldiallylammonium chlor
  • Suitable zwitterionic and amphoteric polymers are, for example, acrylamido- propyl-trimethylammonium chloride / acrylate copolymers, octylacrylamide / acrylate Methylmeth- / tert.Butylaminoethylmethacrylat / 2-hydroxypropyl methacrylate copolymers such as the product Amphomer ® and dimethyl diallyl ammonium chloride-acrylic acid copolymers such as the product Merquat ® 280th
  • Anionic polymers preferred according to the invention are polyacrylic acids and crosslinked polyacrylic acids such as, for example, the commercial products of the Carbopol ® series, in particular Carbopol ® ETD 2020, vinyl acetate / crotonic acid copolymers and terpolymers such as the products of the Luviset ® series, vinylpyrrolidone / vinyl acrylate copolymers, Vinyl acetate / but
  • the preparations according to the invention can be formulated on an aqueous, aqueous-alcoholic or alcoholic basis.
  • Lower alcohols such as ethanol and isopropanol are particularly suitable as alcohols.
  • Aqueous-alcoholic bases can preferably contain water and alcohol in a ratio of 1: 5 to 5: 1.
  • the active ingredient combination according to the invention can be applied to the hair both in the form of a separate formulation or as an additional component in other agents.
  • the preparations according to the invention are formulated as a hair tonic, hair conditioner or as a hair treatment.
  • Hair tonics usually remain on the hair until the next hair treatment, e.g. daily shampooing.
  • Hair rinses are generally formulated in such a way that the active ingredients are rinsed out with water or an at least predominantly water-containing agent after the desired exposure time.
  • the contact time with the hair is usually short.
  • Hair treatments contain the active ingredient combination in a higher concentration than hair rinses and are intended for intensive treatment of the hair and possibly the scalp.
  • the exposure time can be short, for example in the order of the exposure time of hair rinses, but it can also be up to 20 minutes depending on the degree of damage to the hair.
  • the hair treatments according to the invention can also be rinsed out with water or an at least predominantly water-containing agent; but you can also on the Hair left.
  • these agents can be formulated as foam aerosols.
  • the agents can contain propellant gases.
  • the formulation as a pump spray with air as the blowing agent is preferred.
  • the agents according to the invention can include, for example, cleaning agents such as shampoos, setting agents such as hair setting agents, hair sprays and blow dryer waves, permanent shaping agents such as permanent wave and fixing agents, color-changing agents such as bleaching agents, oxidation dyes and tinting agents based on direct dyes, hair lotions and Trade tip fluids.
  • cleaning agents such as shampoos
  • setting agents such as hair setting agents, hair sprays and blow dryer waves
  • permanent shaping agents such as permanent wave and fixing agents
  • color-changing agents such as bleaching agents, oxidation dyes and tinting agents based on direct dyes, hair lotions and Trade tip fluids.
  • the preparations according to the invention can be packaged, for example, as skin care agents and skin cleansers. Particularly in the case of skin treatment agents, those preparations are preferred according to the invention which remain on the body, here the skin, after application.
  • the preparations can be formulated as solutions, oil-in-water emulsions, water-in-oil emulsions, nanoemulsions, microemulsions, in particular those of the PIT type, gels, creams, aerosols or lotions.
  • the preparations can also be in encapsulated form, for example in gelatin or polyvinyl alcohol, as well as in the form of liposomes, e.g. with lecithin.
  • the preparations according to the invention may contain the further constituents customary in these agents.
  • Further common constituents of the preparations according to the invention can thus be: anionic surfactants such as, in particular, alkyl sulfates, alkyl polyglycol ether sulfates and ether carboxylic acids with 10 to 18 carbon atoms in the alkyl group and up to 12 glycol ether groups in the molecule, and also sulfosuccinic acid and dialkyl esters with 8 to 18 carbon atoms in the alkyl group and sulfosuccinic acid mono-alkyl polyoxyethyl ester 8 to 18 carbon atoms in the alkyl group and 1 to 6 oxyethyl groups.
  • anionic surfactants such as, in particular, alkyl sulfates, alkyl polyglycol ether sulfates and ether carboxylic acids with 10 to 18 carbon atoms in the alkyl group and up to 12 glycol ether groups in
  • nonionic surfactants such as, in particular, adducts of 2 to 30 mol of ethylene oxide and / or 0 to 5 mol of propylene oxide with linear fatty alcohols with 8 to 22 C atoms, with fatty acids with 12 to 22 C atoms, with alkylphenols with 8 to 15 C atoms in the alkyl group and corresponding fatty acid amides and fatty amines, -C 22 -C fatty acid mono- and diesters of adducts of 1 to 30 mol ethylene oxide with glycerol, C 8 -C alkyl mono- and oligoglycosides and their ethoxylated analogs, fatty acid N-alkylglucamides , Addition products of 5 to 60 moles of ethylene oxide with castor oil and hardened castor oil, polyol fatty acid esters, sugar esters, sorbitan esters and polysorbates.
  • nonionic surfactants contain polyglycol ether chains, they can have a conventional or narrow homolog distribution.
  • zwitterionic surfactants in particular the so-called betaines such as the N-alkyl-N, N-dimethylammonium glycinate, for example the coconut alkyl dimethylammonium glycinate, N-acylaminopropyl-N, N-dimethylammonium glycinate, for example the coconut acylaminopropyl dimethylammonium glycinate, and 2-alkyl-3-carboxylmethyl-3-hydroxyethyl-imidazolines each having 8 to 18 carbon atoms in the alkyl or acyl group and the cocoacylaminoethylhydroxyethylcarboxymethylglycinate.
  • betaines such as the N-alkyl-N, N-dimethylammonium glycinate, for example the coconut alkyl dimethylammonium glycinate,
  • ampholytic surfactants such as N-alkylglycine, N-alkylpropionic acid, N-alkylamino-butyric acid, N-alkyliminodipropionic acid, N-hydroxyethyl-N-alkylamido propylglycine, N-alkyltaurine, N-alkyl sarcosine, 2-alkylaminopropionic acid and alkylaminoacetic acid each with about 8 to 18 C atoms in the alkyl group, cationic surfactants of the quaternary ammonium compound type, preferably ammonium halides, in particular chlorides and bromides, such as alkyltrimethylammonium chlorides, dialkyldimethylammonium chlorides and trialkylmethylammonium chlorides, for.
  • ammonium halides in particular chlorides and bromides
  • 2-Dihydroxypropyldialkylaminen on the one hand and fatty acids such as caproic acid, caprylic acid, capric acid, lauric acid, myristic acid, palmitic acid, isostearic acid, stearic acid, oleic acid, elaidic acid, arachidic acid, behenic acid and erucic acid or their technical mixtures, as they occur, for example, in the pressure and oil splitting of natural fats such as those available under the trademark Dehyquart® ® and Armocare® ® available products as well as the type of Alkylamidoamine as Stearamidopropyldimethy obtainable under the name Tegoamid ® S 18.
  • fatty acids such as caproic acid, caprylic acid, capric acid, lauric acid, myristic acid, palmitic acid, isostearic acid, stearic acid, oleic acid, elaidic acid, arachidic acid, behenic acid and erucic acid or their
  • dialkyl ethers with a total of between 12 to 36 carbon atoms, in particular 12 to 24 carbon atoms, for example di-n-octyl ether, di-n-decyl ether, di-n-nonyl ether, di- n-undecyl ether and di-n-dodecyl ether, n-hexyl-n-octyl ether, n-octyl-n-decyl ether, n-decyl-n-undecyl ether, n-undecyl-n-dodecyl ether and n-hexyl-n-undecyl ether as well Di-tert-butyl ether, di-isopentyl ether, di-3-ethyl decyl ether, tert-butyl-n-octyl ether
  • Thickening agents such as agar agar, guar gum, alginates, xanthan gum, gelatin, pectins, hydroxyethyl cellulose and polyacrylamides and their copolymers, structurants such as maleic acid,
  • Mono-, di- and oligosaccharides such as glucose, galactose, fructose, fructose and lactose, ceramides, vegetable oils such as jojoba oil, sunflower oil, orange oil, almond oil, wheat germ oil and peach seed oil as well as paraffin oils, saturated and unsaturated, linear and branched fatty alcohols with 8 to 22 carbon atoms and their mixtures, which are reduced by naturally occurring Triglycerides such as beef tallow, palm oil, peanut oil, rape oil, cottonseed oil, soybean oil,
  • Soy lecithin, egg lecithin and cephaline Soy lecithin, egg lecithin and cephaline
  • Solubilizers such as ethanol, isopropanol, ethylene glycol, propylene glycol,
  • Anti-dandruff agents such as piroctone olamine, zinc omadine and climbazole, other substances for adjusting the pH value
  • Active ingredients such as allantoin, pyrrolidone carboxylic acids and bisabolol,
  • Consistency enhancers such as sugar esters, polyol esters or polyol alkyl ethers,
  • Fats and waxes such as walrus, beeswax, montan wax and paraffins,
  • Opacifiers such as latex, styrene / PVP and styrene / acrylamide copolymers
  • Pearlescent agents such as ethylene glycol mono- and distearate and PEG-3 distearate,
  • Complexing agents such as EDTA, NTA, ß-alaninediacetic acid and phosphonic acids, direct dyes so-called coupler and developer components as oxidation dye precursors,
  • Reducing agents such as Thioglycolic acid and its derivatives, thiolactic acid,
  • Oxidizing agents such as hydrogen peroxide, potassium bromate and sodium bromate
  • Blowing agents such as propane-butane mixtures, N 2 O, dimethyl ether, CO 2 , N 2 and air as well
  • the pH of the preparations according to the invention can in principle be between 4.5 and 7, the instabilities known to the person skilled in the art, for example the base body panthenol in an alkaline environment, being taken into account.
  • the pH of the agents according to the invention is preferably between 6 and 6.5. Virtually any acid that can be used for cosmetic purposes can be used to adjust this pH.
  • Food acids are usually used.
  • Edible acids are understood to mean those acids that are ingested as part of normal food intake and have positive effects on the human organism. Examples of edible acids are acetic acid, lactic acid, tartaric acid, citric acid, malic acid, ascorbic acid and gluconic acid. In the context of the invention, the use of lactic acid and citric acid is particularly preferred.
  • Further objects of the invention are the use of a combination of active ingredients, consisting of biotin and at least one glycoprotein, for the treatment of human skin and hair, and the use of this combination of active ingredients for increasing protein production in human cells.
  • Mixture VI is a physiological saline solution diluted by a factor of 10. Unless otherwise noted, all quantities are parts by weight.
  • Phenoxyethanol (and) methylparaben (and) propylparaben) (HENKEL)
  • Polyacrylic acid copolymer (INCI name: Acrylates / C 10-30 alkyl acrylates

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Cosmetics (AREA)

Abstract

L'invention concerne des préparations qui contiennent une combinaison de principe actif, à savoir de biotine et d'au moins une glycoprotéine. Ces préparations augmentent la vitalité cellulaire. Par application d'un agent correspondant sur la peau ou sur les cheveux on a obtenu des accroissements correspondants de la vitalité qui ont eu pour résultat une meilleure élasticité de la peau.
PCT/EP1999/003362 1998-05-27 1999-05-15 Preparation pour le traitement de la peau humaine et des cheveux contenant une combinaison speciale de principes actifs, et utilisation de cette combinaison de principe actif WO1999060989A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP99953283A EP1079795A2 (fr) 1998-05-27 1999-05-15 Preparation pour le traitement de la peau humaine et des cheveux contenant une combinaison speciale de principes actifs, et utilisation de cette combinaison de principe actif
AU42625/99A AU4262599A (en) 1998-05-27 1999-05-15 Preparation for treating human skin and human hair comprising a special active ingredient combination, and the use of this active ingredient combination
CA002333544A CA2333544A1 (fr) 1998-05-27 1999-05-15 Preparation pour le traitement de la peau humaine et des cheveux contenant une combinaison speciale de principes actifs, et utilisation de cette combinaison de principe actif
JP2000550450A JP2002516263A (ja) 1998-05-27 1999-05-15 ヒトの皮膚および毛髪を手入れするための活性成分組み合わせを含有する製剤、並びに該活性成分組み合わせの使用

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823552.6 1998-05-27
DE1998123552 DE19823552A1 (de) 1998-05-27 1998-05-27 Zubereitung zur Behandlung der menschlichen Haut und der menschlichen Haare mit einer speziellen Wirkstoffkombination sowie Verwendung dieser Wirkstoffkombination

Publications (2)

Publication Number Publication Date
WO1999060989A2 true WO1999060989A2 (fr) 1999-12-02
WO1999060989A3 WO1999060989A3 (fr) 2000-03-02

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PCT/EP1999/003362 WO1999060989A2 (fr) 1998-05-27 1999-05-15 Preparation pour le traitement de la peau humaine et des cheveux contenant une combinaison speciale de principes actifs, et utilisation de cette combinaison de principe actif

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EP (1) EP1079795A2 (fr)
JP (1) JP2002516263A (fr)
AU (1) AU4262599A (fr)
CA (1) CA2333544A1 (fr)
DE (1) DE19823552A1 (fr)
WO (1) WO1999060989A2 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001068040A3 (fr) * 2000-03-17 2002-05-16 Oreal Utilisation de sucres et d'extraits vegetaux pour la protection d'un tissu keratinique
WO2001089459A3 (fr) * 2000-05-23 2002-05-23 Oreal Utilisation d'extraits de plantes dans une composition cosmetique pour proteger les fibres cornees
FR2824476A1 (fr) * 2001-05-14 2002-11-15 Clarins Lab Composition cosmetique permettant a la peau de s'adapter aux conditions de stress thermique
GB2402676B (en) * 2003-06-13 2007-11-21 Coletica Cosmetic use by topical application of the lysyl oxidase-like (LOXL) enzyme to stimulate formation of skin elastic fibres
US8691194B2 (en) 2002-12-12 2014-04-08 R.B.T (Rakuto Bio Technologies) Ltd. Methods of producing lignin peroxidase and its use in skin and hair lightening
DE202016003916U1 (de) 2015-06-29 2016-10-11 Hans Werner Bierganns Emulsion

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1318784A1 (fr) * 2000-09-11 2003-06-18 Industria E Comércio de Cosméticos Natura Ltda. Composition de vitamine c et/ou de vitamine a
FR2813789B1 (fr) * 2000-09-11 2003-05-02 Ind E Com De Cosmeticos Natura Nouvelle composition cosmetique ou pharmaceutique comprenant une association de vitamine c et/ou avec un composant fucose, et utilisation de cette association en cosmetique ou pharmacie
JP2002308746A (ja) * 2001-04-05 2002-10-23 Dongsung Pharm Co Ltd 毛髪染色剤の組成物
EP1398019A1 (fr) 2002-09-13 2004-03-17 Cognis France S.A. Procédé pour protéger et moduler la jonction dermo-épidermique
ES2375365T3 (es) * 2004-05-21 2012-02-29 Furusatomura Development Center Co., Ltd. Composición para el cuidado del cabello y del cuero cabelludo.
KR100784486B1 (ko) * 2007-01-08 2007-12-11 주식회사 에스티씨나라 피부 타이트닝용 화장료 조성물 및 이를 이용한 피부타이트닝 방법
JP6185372B2 (ja) * 2013-11-21 2017-08-23 ポーラ化成工業株式会社 皮膚外用剤

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WO2001068040A3 (fr) * 2000-03-17 2002-05-16 Oreal Utilisation de sucres et d'extraits vegetaux pour la protection d'un tissu keratinique
US6861077B1 (en) 2000-03-17 2005-03-01 L'oreal S.A. Use of plant extracts in a cosmetic composition to protect keratinous fibers
WO2001089459A3 (fr) * 2000-05-23 2002-05-23 Oreal Utilisation d'extraits de plantes dans une composition cosmetique pour proteger les fibres cornees
FR2824476A1 (fr) * 2001-05-14 2002-11-15 Clarins Lab Composition cosmetique permettant a la peau de s'adapter aux conditions de stress thermique
US8691194B2 (en) 2002-12-12 2014-04-08 R.B.T (Rakuto Bio Technologies) Ltd. Methods of producing lignin peroxidase and its use in skin and hair lightening
US9693946B2 (en) 2002-12-12 2017-07-04 R.B.T. (Rakuto Bio Technologies) Ltd. Methods of producing lignin peroxidase and its use in skin and hair lightening
GB2402676B (en) * 2003-06-13 2007-11-21 Coletica Cosmetic use by topical application of the lysyl oxidase-like (LOXL) enzyme to stimulate formation of skin elastic fibres
US8906425B2 (en) 2003-06-13 2014-12-09 Basf Beauty Care Solutions France S.A.S. Stimulation of the synthesis of the activity of an isoform of lysyl oxidase-like LOXL for stimulating the formation of elastic fibers
DE202016003916U1 (de) 2015-06-29 2016-10-11 Hans Werner Bierganns Emulsion

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DE19823552A1 (de) 1999-12-02
WO1999060989A3 (fr) 2000-03-02
AU4262599A (en) 1999-12-13
EP1079795A2 (fr) 2001-03-07
JP2002516263A (ja) 2002-06-04
CA2333544A1 (fr) 1999-12-02

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