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WO1999066966A1 - Revetement de type film fin pour implant osseux - Google Patents

Revetement de type film fin pour implant osseux Download PDF

Info

Publication number
WO1999066966A1
WO1999066966A1 PCT/EA1998/000002 EA9800002W WO9966966A1 WO 1999066966 A1 WO1999066966 A1 WO 1999066966A1 EA 9800002 W EA9800002 W EA 9800002W WO 9966966 A1 WO9966966 A1 WO 9966966A1
Authority
WO
WIPO (PCT)
Prior art keywords
layer
bioactive
titanium
sublayer
bioactive layer
Prior art date
Application number
PCT/EA1998/000002
Other languages
English (en)
Russian (ru)
Inventor
Anatoly Dosta
Evgeny Ksenevich
Vadim Savich
Original Assignee
Anatoly Dosta
Evgeny Ksenevich
Vadim Savich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anatoly Dosta, Evgeny Ksenevich, Vadim Savich filed Critical Anatoly Dosta
Priority to PCT/EA1998/000002 priority Critical patent/WO1999066966A1/fr
Publication of WO1999066966A1 publication Critical patent/WO1999066966A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/06—Titanium or titanium alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material

Definitions

  • the claimed invention is not available for medical purposes, and the name for the devices that are used may be used to endanger the use of devices and remote devices.
  • a well-known metal oxide treatment of a cementless endoprosthesis / 2 / performed in two ways. In this case, on a metallic basis from the Soy-Sg- technically the alloy, it is first caused by plasma spraying that is the last from the presence of metal impurities, which is suitable for the elimination of problems
  • the metal oxide coating is applied by plasma spraying with a layer of hydroxyapatite (Ca ⁇ ( ⁇ ) b ( ⁇ ) 2 ), which facilitates the implant integration.
  • a known two-sided metal implant is received / 3 /, which is a combination of a base metal and a non-ignition system.
  • the collection may only be applied to metallic implants from a limited range of metals.
  • this type of implementation does not completely '-' there is a good adhesion of a layer of biologically active material to the core due to varying thicknesses and obstructions ugly charac- teristics, as well as thermal expansions of a tense and difficult-to-accrue word of mouth.
  • the accessibility of the device can be reduced due to a decrease in the speed of acquisitions and the implant, as a whole, due to the fact that the Short-circuited, in the meantime, due to fatigue stresses, expand to the titanium term. In this case, in addition, it is difficult to maintain good bio-mix and an equal area of biological activity. ⁇ . ⁇ . Inevitably involved in the sale of direct contact with the consumer market or even (at home and in the kitchen), there is a need for quick tissue and biological fluids.
  • the claimed invention had the task of creating a joint implant, which would ensure a better adhesion to the substrate, an increase in the adhesion rate. speed, biocompatibility and biological activity, and, at the end of the year, the accelerated integration of the implant in the ⁇ state>
  • P ⁇ s ⁇ avlennaya purpose s ⁇ glasn ⁇ iz ⁇ b ⁇ e ⁇ eniyu ⁇ eshae ⁇ sya on account ⁇ g ⁇ , ch ⁇ in ⁇ n ⁇ len ⁇ chn ⁇ m ⁇ yg. ⁇ i, s ⁇ de ⁇ zhaschem bes ⁇ is ⁇ y ⁇ i ⁇ an ⁇ vy ⁇ dsl ⁇ y, ⁇ ilegayuschy ⁇ ⁇ sn ⁇ ve, bi ⁇ a ⁇ ivny sl ⁇ y and ⁇ mezhu ⁇ chny sl ⁇ y, s ⁇ s ⁇ yaschy from ethyl ma ⁇ e ⁇ ial ⁇ v, v ⁇ dyaschi ⁇ in s ⁇ s ⁇
  • the latter is made from titanium with a number not lower than 99,999 and has a thickness in the range of 0.02-1, 0 ⁇ m.
  • the concentration of oxides of titanium, in the interim, is increasing in the direction of the latter, in the case of biological, which is close to the latter and is very close to the terminal.
  • the content of aluminum and zinc oxides in the intermediate layer does not increase 2–7%, and their concentration decreases the actual biocomplex.
  • the bioactive layer has a thickness of 0.8-1, 1 ⁇ m, the concentration of oxides of titanium is in this range of 93-98%, and the integral thickness is at a rate of 0-3.
  • the biologically active layer in the specified products ensures an optimal combination of speed and biological adhesion.
  • concentration of oxides of titanium in this case in the range of 93-98% also ensures an optimal combination of speed and biocompact.
  • the above-mentioned limits of the integral thickness of the event are also achieved.
  • the last of titanium and the active layer of titanium is performed by the simple and safe all over the base, independently of the world of the past and the middle.
  • the bioactive layer is good even on the inside of the place where the implant and the receiver are located. mi ⁇ - and ma ⁇ she ⁇ ⁇ ⁇ va ⁇ s ⁇ ey, ⁇ azme ⁇ y ⁇ y ⁇ s ⁇ s ⁇ avimy with ⁇ lschin ⁇ y ⁇ y ⁇ iya.
  • the bioactive layer contains the essential oxides of titanium, has grown compound ⁇ .
  • the bioactive layer does not contain nitrogen, hydrogen, carbon and other compounds with other elements, which reduce the rate of adhesion and its adhesion. in a number of cases, the loss of rapid tissue.
  • Bases 1 has an excessive number of active atoms.
  • the content of aluminum and zinc oxides does not increase 2–7% at the same time, and their concentration decreases only in fact, the actual base price is
  • the bioactive layer has a thickness of 0.8-1.1 ⁇ m, the concentration of oxides of titanium in this case is in the range of 93-98%. and the integral thickness of the inventory is in the range of 1, 0-3.0 microns.
  • the bioactive layer contains the proprietary oxides of titanium, has lost the composition of the South 2 .
  • the bioactive layer contains nitrogen, hydrogen, carbon and their compounds with other elements.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Ceramic Engineering (AREA)
  • Prostheses (AREA)

Abstract

Cette invention se rapporte au domaine des techniques médicales, et peut être utilisée en traumatologie et en orthopédie lors de la pose d'endoprothèses pour l'articulation coxo-fémorale. Ce revêtement de type film fin comprend une sous-couche non poreuse en titane qui repose sur une base, une couche bioactive, ainsi qu'une couche intermédiaire qui se compose d'un mélange des matériaux entrant dans la composition de la sous-couche et de la couche bioactive. Cette invention se caractérise en ce que la couche bioactive se compose principalement d'oxydes de titane ayant une composition stoechiométrique différente, par exemple du TiO2, du TiO ou du Ti2O3. La surface de la base possède un nombre excédentaire d'atomes actifs, tandis que la concentration des oxydes de titane dans la couche intermédiaire s'accroît depuis la sous-couche vers la couche bioactive. Des oxydes de d'aluminium et de zirconium sont en outre disposés entre les oxydes de titane selon une concentration qui décroît depuis la sous-couche vers la couche bioactive. L'utilisation, en traumatologie et en orthopédie, d'un implant osseux comportant ce revêtement de type film fin permet d'augmenter la force d'adhérence à la base et d'accroître la densité du revêtement, la résistance à la corrosion, la compatibilité biologique ainsi que l'activité biologique.
PCT/EA1998/000002 1998-06-22 1998-06-22 Revetement de type film fin pour implant osseux WO1999066966A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/EA1998/000002 WO1999066966A1 (fr) 1998-06-22 1998-06-22 Revetement de type film fin pour implant osseux

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EA1998/000002 WO1999066966A1 (fr) 1998-06-22 1998-06-22 Revetement de type film fin pour implant osseux

Publications (1)

Publication Number Publication Date
WO1999066966A1 true WO1999066966A1 (fr) 1999-12-29

Family

ID=8161522

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EA1998/000002 WO1999066966A1 (fr) 1998-06-22 1998-06-22 Revetement de type film fin pour implant osseux

Country Status (1)

Country Link
WO (1) WO1999066966A1 (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1806154A1 (fr) * 2006-01-05 2007-07-11 Howmedica Osteonics Corp. Technique de pulvérisation à vitesse élevée pour des composants d'implants médicaux
US7785317B2 (en) 2006-03-29 2010-08-31 Codman & Shurtleff, Inc. Joined metal tubing and method of manufacture
US7867176B2 (en) 2005-12-27 2011-01-11 Cordis Corporation Variable stiffness guidewire
US8118859B2 (en) 2006-05-26 2012-02-21 Codman & Shurtleff, Inc. Occlusion device combination of stent and mesh having offset parallelogram porosity
US8585732B2 (en) 2006-06-14 2013-11-19 DePuy Synthes Products, LLC Retrieval device with sidewall grippers
US8690938B2 (en) 2006-05-26 2014-04-08 DePuy Synthes Products, LLC Occlusion device combination of stent and mesh with diamond-shaped porosity
US8916198B2 (en) 2006-04-25 2014-12-23 Washington State University Mesoporous calcium silicate compositions and methods for synthesis of mesoporous calcium silicate for controlled release of bioactive agents
JP2015506736A (ja) * 2011-12-22 2015-03-05 デントスプリー・アイエイチ・エービーＤｅｎｔｓｐｌｙ Ｉｈ Ａｂ 酸化チタンによる金属インプラントのブラスト
US9028871B2 (en) 2006-04-25 2015-05-12 Washington State University Resorbable ceramics with controlled strength loss rates
US9327056B2 (en) 2006-02-14 2016-05-03 Washington State University Bone replacement materials

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3722410A1 (de) * 1986-07-21 1988-02-04 Karl Marx Stadt Tech Hochschul Verschleissfeste hueftgelenkpfanne
WO1991003266A1 (fr) * 1989-08-31 1991-03-21 Böhler Ag Prothese
US5192323A (en) * 1990-11-05 1993-03-09 Zimmer, Inc. Method of surface hardening orthopedic implant devices
RU94045951A (ru) * 1992-04-23 1996-09-20 Аксиденталь Ой (FI) Покровный материал и способ его получения, имплантант для биомедицинского использования
RU94046003A (ru) * 1992-05-19 1996-09-27 Вестейм Текнолоджиз Инк. (CA) Модифицированный материал, модифицированный антимикробный материал, способ получения модифицированного материала, способ формирования антимикробного покрытия на устройстве и медицинское устройство, которое предполагается использовать в контакте с электролитом на основе спирта или воды, имеющее на своей поверхности антимикробное покрытие

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3722410A1 (de) * 1986-07-21 1988-02-04 Karl Marx Stadt Tech Hochschul Verschleissfeste hueftgelenkpfanne
WO1991003266A1 (fr) * 1989-08-31 1991-03-21 Böhler Ag Prothese
US5192323A (en) * 1990-11-05 1993-03-09 Zimmer, Inc. Method of surface hardening orthopedic implant devices
RU94045951A (ru) * 1992-04-23 1996-09-20 Аксиденталь Ой (FI) Покровный материал и способ его получения, имплантант для биомедицинского использования
RU94046003A (ru) * 1992-05-19 1996-09-27 Вестейм Текнолоджиз Инк. (CA) Модифицированный материал, модифицированный антимикробный материал, способ получения модифицированного материала, способ формирования антимикробного покрытия на устройстве и медицинское устройство, которое предполагается использовать в контакте с электролитом на основе спирта или воды, имеющее на своей поверхности антимикробное покрытие

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7867176B2 (en) 2005-12-27 2011-01-11 Cordis Corporation Variable stiffness guidewire
EP1806154A1 (fr) * 2006-01-05 2007-07-11 Howmedica Osteonics Corp. Technique de pulvérisation à vitesse élevée pour des composants d'implants médicaux
US10661390B2 (en) 2006-02-14 2020-05-26 Washington State University Bone replacement materials
US9327056B2 (en) 2006-02-14 2016-05-03 Washington State University Bone replacement materials
US7785317B2 (en) 2006-03-29 2010-08-31 Codman & Shurtleff, Inc. Joined metal tubing and method of manufacture
US8916198B2 (en) 2006-04-25 2014-12-23 Washington State University Mesoporous calcium silicate compositions and methods for synthesis of mesoporous calcium silicate for controlled release of bioactive agents
US9028871B2 (en) 2006-04-25 2015-05-12 Washington State University Resorbable ceramics with controlled strength loss rates
US9539359B2 (en) 2006-04-25 2017-01-10 Washington State University Mesoporous calcium silicate compositions and methods for synthesis of mesoporous calcium silicate for controlled release of bioactive agents
US9795716B2 (en) 2006-04-25 2017-10-24 Washington State University Resorbable ceramics with controlled strength loss rates
US8690938B2 (en) 2006-05-26 2014-04-08 DePuy Synthes Products, LLC Occlusion device combination of stent and mesh with diamond-shaped porosity
US8118859B2 (en) 2006-05-26 2012-02-21 Codman & Shurtleff, Inc. Occlusion device combination of stent and mesh having offset parallelogram porosity
US8585732B2 (en) 2006-06-14 2013-11-19 DePuy Synthes Products, LLC Retrieval device with sidewall grippers
JP2015506736A (ja) * 2011-12-22 2015-03-05 デントスプリー・アイエイチ・エービーＤｅｎｔｓｐｌｙ Ｉｈ Ａｂ 酸化チタンによる金属インプラントのブラスト

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