[go: up one dir, main page]

WO1999024070A3 - Derives esters d'acide hyaluronique a proprietes viscoelastiques et leur utilisation dans les domaines biomedical et sanitaire - Google Patents

Derives esters d'acide hyaluronique a proprietes viscoelastiques et leur utilisation dans les domaines biomedical et sanitaire Download PDF

Info

Publication number
WO1999024070A3
WO1999024070A3 PCT/EP1998/007020 EP9807020W WO9924070A3 WO 1999024070 A3 WO1999024070 A3 WO 1999024070A3 EP 9807020 W EP9807020 W EP 9807020W WO 9924070 A3 WO9924070 A3 WO 9924070A3
Authority
WO
WIPO (PCT)
Prior art keywords
hyaluronic acid
biomedical
ester derivatives
viscoelastic properties
healthcare field
Prior art date
Application number
PCT/EP1998/007020
Other languages
English (en)
Other versions
WO1999024070A2 (fr
Inventor
Davide Renier
Alessandra Pavesio
Lanfranco Callegaro
Original Assignee
Fidia Advanced Biopolymers Srl
Davide Renier
Alessandra Pavesio
Lanfranco Callegaro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Advanced Biopolymers Srl, Davide Renier, Alessandra Pavesio, Lanfranco Callegaro filed Critical Fidia Advanced Biopolymers Srl
Priority to AU15598/99A priority Critical patent/AU1559899A/en
Publication of WO1999024070A2 publication Critical patent/WO1999024070A2/fr
Publication of WO1999024070A3 publication Critical patent/WO1999024070A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

L'invention concerne des compositions viscoélastiques comprenant des esters d'acide hyaluronique qui présentent des avantages spécifiques liés à des propriétés viscoélastiques qui varient en fonction de l'effort de cisaillement et de la température.
PCT/EP1998/007020 1997-11-06 1998-11-05 Derives esters d'acide hyaluronique a proprietes viscoelastiques et leur utilisation dans les domaines biomedical et sanitaire WO1999024070A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU15598/99A AU1559899A (en) 1997-11-06 1998-11-05 Ester derivatives of hyaluronic acid with viscoelastic properties and their use in the biomedical and healthcare field

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97PD000253A IT1296689B1 (it) 1997-11-06 1997-11-06 Derivati esterei dell'acido ialuronico aventi proprieta viscoelastiche e loro uso in campo biomedico-sanitario
ITPD97A000253 1997-11-06

Publications (2)

Publication Number Publication Date
WO1999024070A2 WO1999024070A2 (fr) 1999-05-20
WO1999024070A3 true WO1999024070A3 (fr) 1999-07-15

Family

ID=11391956

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/007020 WO1999024070A2 (fr) 1997-11-06 1998-11-05 Derives esters d'acide hyaluronique a proprietes viscoelastiques et leur utilisation dans les domaines biomedical et sanitaire

Country Status (3)

Country Link
AU (1) AU1559899A (fr)
IT (1) IT1296689B1 (fr)
WO (1) WO1999024070A2 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984623B2 (en) 1993-12-07 2006-01-10 Genetics, Institute Institute, LLC. Tendon-inducing compositions
US7091007B2 (en) 1993-09-17 2006-08-15 Genetics Institute, Llc DNA molecules encoding BMP receptor proteins
US7189392B1 (en) 1999-10-15 2007-03-13 Genetics Institute, Llc Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins
US7217691B2 (en) 1986-07-01 2007-05-15 Genetics Institute, Llc Methods of treatment of periodontal disease
US7226587B2 (en) 2001-06-01 2007-06-05 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
US7323445B2 (en) 1999-02-01 2008-01-29 Genetics Institute, Llc Methods and compositions for healing and repair of articular cartilage
US7413753B2 (en) 2001-06-08 2008-08-19 Wyeth Calcium phosphate delivery vehicles for osteoinductive proteins
US9144631B2 (en) 2003-01-27 2015-09-29 Benedicte Asius Ceramic-based injectable implants which are used to fill wrinkles, cutaneous depressions and scars, and preparation method thereof

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1302534B1 (it) * 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per
FR2794763B1 (fr) * 1999-06-08 2001-08-24 Centre Nat Rech Scient Nouveaux derives de l'acide hyaluronique, leur preparation et leur utilisation
EP1454640A3 (fr) * 1999-10-15 2004-09-22 Genetics Institute, LLC Formulations d'acide hyaluronique pour la libération de protéines osteogéniques
US20040037810A1 (en) * 2000-05-03 2004-02-26 Dennis Von Heimburg Biomaterials comprised of preadipocyte cells for soft tissue repair
MXPA03004025A (es) * 2000-11-06 2003-08-19 Alcon Inc Viscoelasticos transitorios no aspirantes para su uso en cirugia.
US7820194B2 (en) 2001-12-21 2010-10-26 Alcon, Inc. Combinations of viscoelastics for use during surgery
TW200638946A (en) 2002-05-17 2006-11-16 Wyeth Corp Injectable solid hyaluronic acid carriers for delivery of osteogenic proteins
US20100098772A1 (en) * 2008-10-21 2010-04-22 Allergan, Inc. Drug delivery systems and methods for treating neovascularization
IT1395392B1 (it) * 2009-08-27 2012-09-14 Fidia Farmaceutici Geli viscoelastici come nuovi filler
CN104725529A (zh) * 2013-12-19 2015-06-24 上海建华精细生物制品有限公司 一种透明质酸衍生物的合成方法
CZ307158B6 (cs) * 2016-12-23 2018-02-07 Contipro A.S. Oftalmologický prostředek
IT201900019762A1 (it) * 2019-10-24 2021-04-24 Fidia Farm Spa Composizione farmaceutica per uso nel trattamento della cistite di varia eziologia

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0216453A2 (fr) * 1985-07-08 1987-04-01 FIDIA S.p.A. Esters de l'acide hyaluronique et leurs sels.
EP0341745A1 (fr) * 1988-05-13 1989-11-15 FIDIA S.p.A. Polysaccharides carboxylés réticulés
WO1996037519A1 (fr) * 1995-05-22 1996-11-28 Fidia Advanced Biopolymers S.R.L. Hydrogel polysaccharide, son procede de preparation et son utilisation en medecine, en chirurgie, en cosmetique et pour la preparation de produits d'hygiene
WO1997049412A1 (fr) * 1996-06-21 1997-12-31 Fidia S.P.A. Acide hyaluronique autoreticule et compositions pharmaceutiques associees pour le traitement des arthropathies

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0216453A2 (fr) * 1985-07-08 1987-04-01 FIDIA S.p.A. Esters de l'acide hyaluronique et leurs sels.
EP0341745A1 (fr) * 1988-05-13 1989-11-15 FIDIA S.p.A. Polysaccharides carboxylés réticulés
WO1996037519A1 (fr) * 1995-05-22 1996-11-28 Fidia Advanced Biopolymers S.R.L. Hydrogel polysaccharide, son procede de preparation et son utilisation en medecine, en chirurgie, en cosmetique et pour la preparation de produits d'hygiene
WO1997049412A1 (fr) * 1996-06-21 1997-12-31 Fidia S.P.A. Acide hyaluronique autoreticule et compositions pharmaceutiques associees pour le traitement des arthropathies

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 9739, Derwent World Patents Index; Class B04, AN 97-418785, XP002102269 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7217691B2 (en) 1986-07-01 2007-05-15 Genetics Institute, Llc Methods of treatment of periodontal disease
US7300772B2 (en) 1986-07-01 2007-11-27 Genetics Institute, Llc BMP products
US7091007B2 (en) 1993-09-17 2006-08-15 Genetics Institute, Llc DNA molecules encoding BMP receptor proteins
US6984623B2 (en) 1993-12-07 2006-01-10 Genetics, Institute Institute, LLC. Tendon-inducing compositions
US7365052B2 (en) 1993-12-07 2008-04-29 Genetics Institute, Llc. Tendon-inducing methods
US7323445B2 (en) 1999-02-01 2008-01-29 Genetics Institute, Llc Methods and compositions for healing and repair of articular cartilage
US7189392B1 (en) 1999-10-15 2007-03-13 Genetics Institute, Llc Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins
US7226587B2 (en) 2001-06-01 2007-06-05 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
US7413753B2 (en) 2001-06-08 2008-08-19 Wyeth Calcium phosphate delivery vehicles for osteoinductive proteins
US9144631B2 (en) 2003-01-27 2015-09-29 Benedicte Asius Ceramic-based injectable implants which are used to fill wrinkles, cutaneous depressions and scars, and preparation method thereof

Also Published As

Publication number Publication date
AU1559899A (en) 1999-05-31
IT1296689B1 (it) 1999-07-14
ITPD970253A1 (it) 1999-05-06
WO1999024070A2 (fr) 1999-05-20
ITPD970253A0 (it) 1997-11-06

Similar Documents

Publication Publication Date Title
WO1999024070A3 (fr) Derives esters d'acide hyaluronique a proprietes viscoelastiques et leur utilisation dans les domaines biomedical et sanitaire
EP0265116A3 (fr) Esters réticulés d'acide hyaluronique
DE60024612D1 (de) Verfahren zur herstellung von konditionierten zellkulturmedium-zusammensetzungen
MY127430A (en) Solid lipid formulations comprising an inhibitor of lipases and a fatty acid ester of polyols
AU7442398A (en) Glucosamine fatty acid compositions and their use
AU9164298A (en) Use of organic acid esters in food products
DE69534669D1 (de) Nukleinsaeure enthaltende zusammensetzungen, herstellung und verwendung
DE69635609D1 (de) Nukleinsäure enthaltende zusammensetzung, herstellung und verwendung
WO1997042975A3 (fr) Compositions a base de chitosane et procedes de diffusion d'acides nucleiques dans une cellule
BRPI0210011B8 (pt) cateter com septo de arrasto reduzido.
CA2282183A1 (fr) 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines hydroxy substitue
MY130670A (en) 4-carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
MY121838A (en) 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines
BR9908578A (pt) Composição cosmética
WO1991005754A3 (fr) Derives des alcools gras a longue chaine, leurs applications, notamment en tant que molecules cytotrophiques et cytoprotectrices, et compositions pharmaceutiques les contenant
DE69031732D1 (de) Verfahren zur herstellung von glykosid-estern und zusammensetzungen daraus
WO2001040240A3 (fr) Dérivés de monosaccharides et de disaccharides
EP1219636A3 (fr) Mutéines d'érythropoiétine (EPO) modifiées, produites par des systèmes d'expression microbiologiques in vitro ou in vivo
CA2022177A1 (fr) Arginine deiminase, methode de production, et agent anti-cancereux contenant cette enzyme comme ingredient efficace
DE69635670D1 (de) Threitol-buttersäureester-enthaltende zusammensetzungen und ihre verwendung
WO2003008457A3 (fr) Esters polysaccharidiques d'acide retinoique
HK1040402A1 (zh) 使用乳粘素(lactadherin)或其變體的的方法及其組合物
WO2005107828A3 (fr) Articles médicaux inserables ou implantables ayant des surfaces biocompatibles modifiees covalentes
WO1999038821A3 (fr) Composes transfectants sensibles aux conditions reductrices, compositions pharmaceutiques les contenant, et leurs applications
EP1066816A4 (fr) Agents favorisant la production de laminine dans les cellules de la peau

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
NENP Non-entry into the national phase

Ref country code: KR

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA