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WO1999037759A3 - Live attenuated salmonella vaccine - Google Patents

Live attenuated salmonella vaccine Download PDF

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Publication number
WO1999037759A3
WO1999037759A3 PCT/BE1999/000007 BE9900007W WO9937759A3 WO 1999037759 A3 WO1999037759 A3 WO 1999037759A3 BE 9900007 W BE9900007 W BE 9900007W WO 9937759 A3 WO9937759 A3 WO 9937759A3
Authority
WO
WIPO (PCT)
Prior art keywords
seq
live attenuated
attenuated salmonella
salmonella vaccine
animal
Prior art date
Application number
PCT/BE1999/000007
Other languages
French (fr)
Other versions
WO1999037759A2 (en
Inventor
Elina Gubbels
Greve Henri De
Jean-Pierre Hernalsteens
Original Assignee
Univ Bruxelles
Elina Gubbels
Greve Henri De
Hernalsteens Jean Pierre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP98870019A external-priority patent/EP0943681A1/en
Application filed by Univ Bruxelles, Elina Gubbels, Greve Henri De, Hernalsteens Jean Pierre filed Critical Univ Bruxelles
Priority to AU21444/99A priority Critical patent/AU2144499A/en
Publication of WO1999037759A2 publication Critical patent/WO1999037759A2/en
Publication of WO1999037759A3 publication Critical patent/WO1999037759A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/255—Salmonella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention is related to a vaccine for inducing an immune response to a Salmonella strain in an animal, including a human, characterised in that it comprises a pharmaceutically acceptable carrier and a genetically modified Salmonella strain which is in an amount effective to produce an immune response in said animal, including human, and comprises a modification in its wild type DNA sequence SEQ ID NO 09, any of the DNA sequences from the same operon as a wild type DNA sequence selected from the group consisting of SEQ ID NO 01, SEQ ID NO 14, SEQ ID NO 15 and SEQ ID NO 16, and/or any regulatory sequences of any of the said DNA sequences.
PCT/BE1999/000007 1998-01-22 1999-01-22 Live attenuated salmonella vaccine WO1999037759A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU21444/99A AU2144499A (en) 1998-01-22 1999-01-22 Live attenuated salmonella vaccine

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP98870019A EP0943681A1 (en) 1998-01-22 1998-01-22 Live attenuated salmonella vaccine
EP98870019.1 1998-01-22
EP98870202.3 1998-09-24
EP98870202 1998-09-24

Publications (2)

Publication Number Publication Date
WO1999037759A2 WO1999037759A2 (en) 1999-07-29
WO1999037759A3 true WO1999037759A3 (en) 1999-10-14

Family

ID=26152226

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BE1999/000007 WO1999037759A2 (en) 1998-01-22 1999-01-22 Live attenuated salmonella vaccine

Country Status (2)

Country Link
AU (1) AU2144499A (en)
WO (1) WO1999037759A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1252180A2 (en) * 2000-02-03 2002-10-30 Microscience Limited Virulence genes, proteins, and their use
UA100370C2 (en) 2006-12-11 2012-12-25 Мериал Лимитед METHOD OF VACCINATION OF BIRDS AGAINST SALMONELL
CN103197078B (en) * 2013-03-28 2015-04-08 扬州大学 Application of salmonella pullorum secreted protein SpiC
CN112546210A (en) * 2020-12-15 2021-03-26 南京农业大学 Preparation method and application of salmonella inactivated vaccine

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996017951A2 (en) * 1994-12-09 1996-06-13 Rpms Technology Limited Identification of genes responsible for in vivo survival of microorganisms
WO1997029768A1 (en) * 1996-02-15 1997-08-21 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Salmonella typhimurium vaccine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996017951A2 (en) * 1994-12-09 1996-06-13 Rpms Technology Limited Identification of genes responsible for in vivo survival of microorganisms
WO1997029768A1 (en) * 1996-02-15 1997-08-21 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Salmonella typhimurium vaccine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
E. HOHMANN ET AL.: "Evaluation of a phoP/phoQ-deleted, aroA-deleted live oral Salmonella typhi vaccine strain in human volunteers.", VACCINE, vol. 14, no. 1, January 1996 (1996-01-01), AMSTERDAM, NL, pages 19 - 24, XP002068852 *
R. CURTISS III ET AL.: "Nonrecombinant and recombinant avirulent Salmonella vaccines for poultry", VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, vol. 54, no. 1-4, November 1996 (1996-11-01), AMSTERDAM, NL, pages 365 - 372, XP002068851 *
S. MILLER ET AL.: "A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE U.S.A., vol. 86, no. 13, July 1989 (1989-07-01), WASHINGTON, DC, USA, pages 5054 - 5058, XP002068853 *

Also Published As

Publication number Publication date
AU2144499A (en) 1999-08-09
WO1999037759A2 (en) 1999-07-29

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