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WO1999037778A3 - Compositions and methods for detecting and treating prostate cancer - Google Patents

Compositions and methods for detecting and treating prostate cancer Download PDF

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Publication number
WO1999037778A3
WO1999037778A3 PCT/US1999/001721 US9901721W WO9937778A3 WO 1999037778 A3 WO1999037778 A3 WO 1999037778A3 US 9901721 W US9901721 W US 9901721W WO 9937778 A3 WO9937778 A3 WO 9937778A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
methods
prostate cancer
detecting
treating prostate
Prior art date
Application number
PCT/US1999/001721
Other languages
French (fr)
Other versions
WO1999037778A2 (en
Inventor
Nan Zhang
Paul B Fisher
Neil I Goldstein
Fei Huang
Jennifer R Adelman
Original Assignee
Genquest Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genquest Inc filed Critical Genquest Inc
Priority to AU24746/99A priority Critical patent/AU2474699A/en
Publication of WO1999037778A2 publication Critical patent/WO1999037778A2/en
Publication of WO1999037778A3 publication Critical patent/WO1999037778A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5156Animal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Compositions and methods for the detection and therapy of prostate cancer are disclosed. The compounds provided include tumor-associated proteins, and portions and variants thereof, as well as polynucleotides that encode such polypeptides. Vaccines and pharmaceutical compositions comprising such compounds are also provided and may be used, for example, for cancer prevention and treatment. The polypeptides may also be used for the production of antibodies, which are useful for diagnosing and monitoring cancer progression in a patient.
PCT/US1999/001721 1998-01-26 1999-01-26 Compositions and methods for detecting and treating prostate cancer WO1999037778A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU24746/99A AU2474699A (en) 1998-01-26 1999-01-26 Compositions and methods for detecting and treating prostate cancer

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7254298P 1998-01-26 1998-01-26
US7329598P 1998-01-26 1998-01-26
US60/072,542 1998-01-26
US60/073,295 1998-01-26

Publications (2)

Publication Number Publication Date
WO1999037778A2 WO1999037778A2 (en) 1999-07-29
WO1999037778A3 true WO1999037778A3 (en) 1999-11-11

Family

ID=26753473

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/001721 WO1999037778A2 (en) 1998-01-26 1999-01-26 Compositions and methods for detecting and treating prostate cancer

Country Status (2)

Country Link
AU (1) AU2474699A (en)
WO (1) WO1999037778A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994009820A1 (en) * 1992-11-05 1994-05-11 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen
WO1996021671A1 (en) * 1995-01-11 1996-07-18 The Trustees Of Columbia University In The City Of New York Development of dna probes and immunological reagents specific for cell surface-expressed molecules and transformation-associated genes
WO1997008318A2 (en) * 1995-08-25 1997-03-06 Corixa Corporation Compounds and methods for treatment and diagnosis of prostate cancer
WO1997033909A2 (en) * 1996-03-15 1997-09-18 Corixa Corporation Compounds and methods for immunotherapy and immunodiagnosis of prostate cancer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994009820A1 (en) * 1992-11-05 1994-05-11 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen
WO1996021671A1 (en) * 1995-01-11 1996-07-18 The Trustees Of Columbia University In The City Of New York Development of dna probes and immunological reagents specific for cell surface-expressed molecules and transformation-associated genes
WO1997008318A2 (en) * 1995-08-25 1997-03-06 Corixa Corporation Compounds and methods for treatment and diagnosis of prostate cancer
WO1997033909A2 (en) * 1996-03-15 1997-09-18 Corixa Corporation Compounds and methods for immunotherapy and immunodiagnosis of prostate cancer

Also Published As

Publication number Publication date
WO1999037778A2 (en) 1999-07-29
AU2474699A (en) 1999-08-09

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