[go: up one dir, main page]

WO1999038547A3 - Revetements pour implants medicaux presentant une biocompatibilite amelioree - Google Patents

Revetements pour implants medicaux presentant une biocompatibilite amelioree Download PDF

Info

Publication number
WO1999038547A3
WO1999038547A3 PCT/US1999/001766 US9901766W WO9938547A3 WO 1999038547 A3 WO1999038547 A3 WO 1999038547A3 US 9901766 W US9901766 W US 9901766W WO 9938547 A3 WO9938547 A3 WO 9938547A3
Authority
WO
WIPO (PCT)
Prior art keywords
coatings
medical implants
compound
anticlotting
enhanced biocompatibility
Prior art date
Application number
PCT/US1999/001766
Other languages
English (en)
Other versions
WO1999038547A2 (fr
Inventor
Michael Helmus
Michael J Scott
Original Assignee
Baxter Int
Michael Helmus
Michael J Scott
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Michael Helmus, Michael J Scott filed Critical Baxter Int
Priority to CA002318736A priority Critical patent/CA2318736A1/fr
Priority to AU24765/99A priority patent/AU2476599A/en
Priority to BR9908533-0A priority patent/BR9908533A/pt
Priority to EP99904351A priority patent/EP1051210A2/fr
Priority to JP2000529278A priority patent/JP2002501789A/ja
Publication of WO1999038547A2 publication Critical patent/WO1999038547A2/fr
Publication of WO1999038547A3 publication Critical patent/WO1999038547A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0017—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using a surface active agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

On décrit des revêtements pour implants médicaux présentant une biocompatibilité améliorée, des dispositifs médicaux à irradiation aiguë et des procédés de production desdits éléments. Ces revêtements biocompatibles sont particulièrement avantageuses lorsqu'ils sont utilisés en association avec des matériaux ayant une étendue de la surface élevée (résines poreuses, tissus et textiles, par exemple), et comprennent des complexes liés par migration des ions d'au moins un composé anticoagulant et d'au moins un composé d'ammonium quaternaire présentant plus de 0,15 et moins de 40 IU du composé anticoagulant par cm2. Ces sont produits par formation d'une solution du complexe ayant une concentration supérieure à 0,005 et inférieure à 1,5 p/v qu'on applique sur la surface et laisse sécher. Ces revêtements réduisent la propension au dépôt de thrombus sans nuire à la guérison ou à la croissance interne du tissu à l'intérieur du dispositif.
PCT/US1999/001766 1998-01-30 1999-01-28 Revetements pour implants medicaux presentant une biocompatibilite amelioree WO1999038547A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002318736A CA2318736A1 (fr) 1998-01-30 1999-01-28 Revetements pour implants medicaux presentant une biocompatibilite amelioree
AU24765/99A AU2476599A (en) 1998-01-30 1999-01-28 Enhanced biocompatibility coatings for medical implants
BR9908533-0A BR9908533A (pt) 1998-01-30 1999-01-28 Revestimento de biocompatibilidade melhorada para implantes médicos e dispositivos médicos de exposição aguda, processo para produção de um revestimento de biocompatibilidade melhorada, e, implante médico ou dispositivo médico de exposição aguda
EP99904351A EP1051210A2 (fr) 1998-01-30 1999-01-28 Revetements pour implants medicaux presentant une biocompatibilite amelioree
JP2000529278A JP2002501789A (ja) 1998-01-30 1999-01-28 医療用インプラントのための生体適合性を増強したコーティング

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1614798A 1998-01-30 1998-01-30
US09/016,147 1998-01-30

Publications (2)

Publication Number Publication Date
WO1999038547A2 WO1999038547A2 (fr) 1999-08-05
WO1999038547A3 true WO1999038547A3 (fr) 1999-09-23

Family

ID=21775639

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/001766 WO1999038547A2 (fr) 1998-01-30 1999-01-28 Revetements pour implants medicaux presentant une biocompatibilite amelioree

Country Status (6)

Country Link
EP (1) EP1051210A2 (fr)
JP (1) JP2002501789A (fr)
AU (1) AU2476599A (fr)
BR (1) BR9908533A (fr)
CA (1) CA2318736A1 (fr)
WO (1) WO1999038547A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060257355A1 (en) * 2005-05-10 2006-11-16 Abiomed, Inc. Impregnated polymer compositions and devices using them

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993005825A1 (fr) * 1991-09-20 1993-04-01 Baxter International Inc. Procedes permettant de reduire la thrombogenicite de biomateriaux
WO1993021860A1 (fr) * 1992-05-07 1993-11-11 Intervascular, Inc. Prothese vasculaire non thrombogene
US5679400A (en) * 1993-04-26 1997-10-21 Medtronic, Inc. Intravascular stent and method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993005825A1 (fr) * 1991-09-20 1993-04-01 Baxter International Inc. Procedes permettant de reduire la thrombogenicite de biomateriaux
WO1993021860A1 (fr) * 1992-05-07 1993-11-11 Intervascular, Inc. Prothese vasculaire non thrombogene
US5679400A (en) * 1993-04-26 1997-10-21 Medtronic, Inc. Intravascular stent and method

Also Published As

Publication number Publication date
EP1051210A2 (fr) 2000-11-15
WO1999038547A2 (fr) 1999-08-05
AU2476599A (en) 1999-08-16
JP2002501789A (ja) 2002-01-22
CA2318736A1 (fr) 1999-08-05
BR9908533A (pt) 2000-11-28

Similar Documents

Publication Publication Date Title
CA2194462A1 (fr) Agent activant la regeneration de tissu dur
RU97102352A (ru) Агент, стимулирующий твердую ткань
WO1994007432A3 (fr) Implants vasculaires poreux
CA2183263A1 (fr) Procede ameliore de fixation d'un tissu biologique resistant a la calcification
EP2407135A3 (fr) Structures absorbantes de fibres cellulosiques traitées chimiquement
SE9901973D0 (sv) Implantat för applicering i ben och förfarande och användning vid sådant implantat
FI952701A0 (fi) Metallisen kirurgisen istukkaan käsittelymenetelmä
CA2158638A1 (fr) Composition et methode d'augmentation tissulaire
MY121999A (en) Inclusion complexes of aryl-heterocyclic salts
NO2014010I2 (fr)
WO2002035988A3 (fr) Greffe comportant une region de formation de fermeture biologique
ATE281804T1 (de) Korbartiger behälter zum implantieren von knochengewebe
CA2261806A1 (fr) Dispositifs medicaux renfermant des composes medicaux generes in situ
WO2000032247A3 (fr) Tissu antimicrobien et greffe medicale constituee de ce tissu
EP1712228A3 (fr) Derivées de l' acide hyaluronique destinées au traitement des cicatrices de la peaux
CA2332532A1 (fr) Biomateriaux a base de derives d'acide hyaluronique sous forme de structures tridimensionnelles depourvues de composants cellulaires ou de produits de ces derniers pour la regeneration in vivo de cellules tissulaires
EP0328971A3 (fr) Méthode de préparation des fibres cellulosiques ayant eine absorption modifiée
De Groot Hydroxylapatite coatings for implants in surgery
WO1999038547A3 (fr) Revetements pour implants medicaux presentant une biocompatibilite amelioree
EP0475383A3 (en) Polysaccharide composition or polysaccharide having heparinoid activity, process for producing the same, and anticoagulant containing the same as active ingredient
CN110772662A (zh) 一种抗菌膨体聚四氟乙烯面部植入材料及其制备工艺
EP1157708A3 (fr) Articles chirurgicaux antimicrobiens
ES2062896T3 (es) Material implantable biodegradable y procedimiento de fabricacion.
YU17002A (sh) Upotreba deksrazoksana u lečenju psorijaze
HUT59011A (en) Process for producing composition, and its active ingredient, suitable for inactivating or removing harmful compounds in blood and other extracellular liquids

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
ENP Entry into the national phase

Ref document number: 2318736

Country of ref document: CA

Ref country code: CA

Ref document number: 2318736

Kind code of ref document: A

Format of ref document f/p: F

ENP Entry into the national phase

Ref country code: JP

Ref document number: 2000 529278

Kind code of ref document: A

Format of ref document f/p: F

NENP Non-entry into the national phase

Ref country code: KR

WWE Wipo information: entry into national phase

Ref document number: 1999904351

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1999904351

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 1999904351

Country of ref document: EP